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                  <text>"’f‘mm’w" 'un-W‘

:r’alww .mu-zw—a—wwq-p-mvm

w-“

July 3, 1970
President
Mallinckrodt Chemical works

St. Louis, hissouri
Dear

Sir,

Since 1968, we have carried out clinical studies of
naloxone in the treatment of’opiate dependence. Supplies have been
provided by Endb Laboratories, but they have been unable to
make sufficient nalosone available for oral studies. In December
we requested additional supplies and these have not been forthcoming;
they have indicated that the supplies are male in your laboratories.

In discussing this with the officials of the New York State
Narcotic Addiction Cbntrol commission, they offered to make funds
available for our independent purchase of'naloxone; and such a
contract has been received by this Department.
would like to purchase 3 kilograms of'nalcxone; preferably
in 300 or 500 mgm tablets or capsules. Is it possible for
your laboratories to make such a quantity available? At what cost
we

made up

and with what delivery schedule ?

are unable to supply this quantity, can you direct
If youlaboratories
either here or abroad that can ?
other
to
us
an...

We

am..-

'1

--

either

U.S. customs,

have

or can obtain the necessary

etc. clearances.

FDA, BNDD,

my".

Thank you.

Sincerely yours,
Max

Fink,

M. D.

Professor of Psychiatry

mf/
cc:

Endb

Laboratories

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