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July 10, 1970
Mr. Joseph

Lelyvald

The New York Times
229 was: 43rd

New

York,

New

Street

York

Dear Mr. Lelyveld:

I was pleased to have the opportunity today to continue our
conversation, although, I must admit, that I was distressed by
the turn of events.
of the June 4 meeting on Mucous Antagonists in
Opiate Dependence is enclosed, with s list of participants. This
summary has been accepted for publication in Science.
The summary

We

have been

notified by representatives of the

Endo

Division

of DuPont — Mr. Joseph Conlon, Vice~President of DuPont and two
associates — that they would no longer support studies of naloxone
in the therapy of opiate dependence; specifically, they would not
approve studies under

tion) before the

clinical trials.

FDA,

their

IND

(Investigational

nor would they

make

New Drug Applica—

supplies available for

I indicated that we were prepared to purchase a supply sufficient
for our immediate needs, 6 kilograms, at an approximate price of
$10,000 per kilogram - a price suggested in 1969 by Mr. David Kline

of Endo Laboratories.

since

,um‘u

"W”,hwm‘

”new: rnmmm-qvvv-mqu-"w-,m-.-.._.....,

a

.

it

was

Mr. Conlon asked us

unlikely that they

would honor

Our request was sent today, and a copy

copy of a

not to

it.

make

this request

is enclosed. Also, a

letter sent to other participants of the

June

4

meeting.

is to obtain supplies of naloxone for clinical trial.
either Endo or DuPont in their une
Any
decision.
help
you can give us to attain our primary
fortunate
be
that, we will cooperate fully
Failing
appreciated.
goal will
American
Our aim

We

have no need to embarrass

to make the complete antagonist story available to the
press - a story with many strange and sordid elements.

�~2‘

Hr. Lclyvnld

hnvc 1130 brought this issue to tho attcntton
CBS Noun, a friend and follower of our work,
havc Icrvcd an ad hoe consultant: on nu-crous occasions.

Incidcntclly, ﬂ!

chll

of Mr. Burl
and for whom

v.

of

Thluk you in advance for your holp.

Sinccrcly yours,
Pink. M.D.
Professor of Paychiatry

Max

ﬁrzkt

July 10, 1970

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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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