http://exhibits.library.stonybrook.edu/mfp/files/original/4b0110c5de4bbe263d5bc9ed7b39a4dc.pdf 8fb66c7cfc07eced258520268456a514 PDF Text Text MAILED T0: DR. DOROTHY DOBBS 1600 s. Eads Arllngton, Virginia 22202St . ’ Apt' 432N _ July 23, 1970 Dr. Dorothy Dobbs Section of Neuropharmacology Food and Drug Administration Washington, D.C. Dear Dorothy, It was a pleasure talking with you today, and finding that views on the proposed guidelines for drug evaluations were our essentially in agreement, reassured me. Thanks. Enclosed is a copy of the summary of the June 4 meeting on Narcotic Antagonists in Opiate Dependence. It will be published in Science. The participants included clinicians, pharmacologists and chemists with experience in the antagonists. We concluded that: (l) The antagonist model was both clinically useful and theoretically interesting; (2) Available antagonists, cyclazocine and naloxone, were safe and further studies should continue; (3) A long-acting antagonist was the ideal immunizing agent and every effort should be made to enhance such a development. We are continuing our clinical studies of cyclazocine; have been reassured (after much difficulty [see New Yerk Times, August 14]) of our supplies of naloxone for one year; and have contract support from the New York State Narcotic Addiction Control Commission to develop a long acting antagonist. (We also are continuing a methadone maintenance program and are studying the duration of L-alpha—acetylmethadol, using heroin challenges as our index of duration of cross—tolerance.) FDA It would be an honor, and committee program. There interesting, to participate in the is surely need for continuing evaluations of the methadone and other opiate treatment programs. My curriculum and I have been cleared for U. S. governmental vitae is enclosed; activity. My best regards. Sincerely yours, Max Fink, M.D. Professor of Psychiatry MF:kt enc. � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Dobbs, Dorothy Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-024-7-314 Date A point or period of time associated with an event in the lifecycle of the resource 1970 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence