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                  <text>ﬂay

i, |970

Dear fir. Refer: :
On

ihe advice of Professor Danlal Efren 0f fhe National insilfufe
i am
adﬂresslng lhls lefler f0 ask whefher your

of Manfal Healfh,

laboraforles

can produce

clinical quanfilles of Naioxono,

narcnflc anlaganisf, for our sfudlas.

a

Naioxone (l~n~aliyl~7,8-dlhydrn—l4~hydr0xynormorphlnone
hydrochloride) is useful in freatlng
dependence,
but The clinical irlals have been law,opiate
llmlfnd by an lnadequafe
supply. As l understand the problem, naloxona is produced from
Thebaine, and if is The prescription of lhls compound which
curfalls

producllon.
We

have found That 3.0

oral naloxone a day are naeded +0
and would lika f0 verify fhis
observation in a clinical lrlal. wﬁ need 2-4 kilograms naloxone,
and i am wriflng f0 inquire whether Maker Chemical
produca
lhls cempcund in fhis quanfify; and if 30, a? whaf can
and in
ccsi
whai lime. WE are capable of wrlfing a
contract
60 days,
wilhin
and wmuld hmpe lo d0 5G as soon as a bid is received. While
is on fhe narcoflc iisTs-of This caunfry, we have haen assurednaloxona
nf fhe necassary impart llcansas; and as fhls supply will
net be
sold, are assured of fhe coop@ra+lon mi The licensee.

sustain antagonism

i

To

Gms

cplafes,

look forward To hearing from you.

Sincarely yours,

m1wwarumw.

Max Flak, M.D.
Professor of Psychiafry

Mfzkp

cc: Dr.

A. M. Freedman
Dr. 3. Efren

“‘th-

r
-

7.-:I.k.-a

AIR LETTER:

Dr. Z. Rofen

Direcfor

Chemical Lfd.
6570

MAKOR

PO

Jerusalem, lsratl

f
my!

SW!)

15%

‘

-.-an

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              <text>Correspondence to: Roten, ?</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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