http://exhibits.library.stonybrook.edu/mfp/files/original/05081ae6f433cf8e856a632ed863891b.pdf ae1ed145b5dc240f50f5ab28d92f8b0a PDF Text Text .m_ww.m mmwm'wm n—wrwaw 4‘: «2-— March 20, 1970 Mr. Max Singer, Prosident Hudson Institute Quaker Ridge Road Crotcn—on~Hudson, New York 10520 Dear Mr. Singer: ouch has happened sinco I received your interesting letter of notch 12. I appeared beforo Senators Hughes and Javits in support of a proposed bill (S~3562) to establish a division of HEW dedicated to a national effort in treating and studying drug depondonce. Mr. Javita became interested in antagonists and when his office called NINE, they were told that our was rejected. contract for a long acting naloxone is to your questions. present Facts or dogma; but unsolicited Most are unanswerable according to here are some tries. ”Craving“ after detoxification as a metaphor, “there is nothing in his body which one can hope to influence”: There is that tissue cells change when exposed to opiates, and a single exposure, are long lasting. When animals are exposed to an opiate days or weeks after the initial exposure, their response (however measured) is significantly altered from the response of unexposed animals. Thus, opiates are a some evidence that such changes, even after potent signal and ono~trial [or fow~trial1 learning occurs ~ with consolidation of “learned“ behavior very rapid and persistent. Such evidence supports the view of opiate dependence as a biological How to induce “unloarning” or forgetting is our problem. problem. We need means to enable selective forgetting (g;g;, in such diverse illnesses an phobias, allergies. penicillin and rfi sensitivity, 935;), and the “cure” of opiate dependence may be viewed in this framework. By the dictionary, it may not be a ”medical“ problem, but it is a biologic, not a aociologic, problem. �nw-w-v—IVWW »V..-———-.wW——n..—..w ‘W~WW WWW—“WW""a... ,_ . Mr. w. . . ,7 Wwe... 1.. pm_—w.wwmmm. Maw—.wm. .. . -2- Singer March 20, 1970 The problem with methadone maintenance (and 2 ’ . heroin maintenance) is that these agents consolidate learning. A principal hone of treatment by antagonists is that they may serve to reduce opiate "memories.” . H of ldroin Addiction: A spontaneous cure reflects some subjects to resist tissue demands for opiates fer sufficiently long periods to reduce tissue changes by disuse atrophy. Whether the drive to withstand tissue demands is socially determined (as in asceticism), physically (as in incarceration) or biologically (antagonists) may be irrelevant to the outcome of discontinued addiction. RAV is an interesting term that needs clearer definition. The Nature the ability of ._m.ww_,m,uus WV. “Wu—A .« Hwy «r -. ..v7-—.r‘—vr”mMW-Irmv-——M Heroin Use and Disease: Some interesting ideas, I have responded with marginal notes, agreeing with most, and disagreeing with some. 1. A reason for reducing a habit may be expense and strain, but this sounds like a rationalization. Perhaps, a reduction in drive for opiates occurs because of hormonal changes (stress, age) or after an illness which may alter tissue responsiveness. 2. Like with other addictions, as alcohol, tobacco or barbiturates, seems necessary to assure availability of the drugs. social participation shawl- cw,- :wgq.;n~v Perhaps contagion is re—enforced in opiates because users know To assure an adequate supnly, they wish to increase their connections, so that if one connection is disrupted, others will be available to sustain the dependence. 3. it is illegal, ”pr w— ., 4. Theoretically balanced, but is there any evidence? had apple in the barrel analogy is applicable. 5. Surely, [repeated] exposure to opiates is the necessary likely, the ,wvwwrwrwmwl and sufficient causal factor. These are .‘y ”.7,” More my responses. Perhaps I am over-emphasizing the biological bases of addiction, but this model seems to provide a better theoretical framework for the study of your questions than sociologic or psychologic theories. I look forward to your recommendations - which I hope will some other techniques balance the psycho-mania and methadone-mania with for study. Sincerely yours, rwfiwww :‘zax Fink ’ :51. D a Professor of Psychiatry Mszp � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Singer, Max Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-024-3-099 Date A point or period of time associated with an event in the lifecycle of the resource 1970 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. 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