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                  <text>”r.‘me-WVM7

-

yam

w-

March 26, 1970

Dr. E. Leong way

Department of Pharmacology
University of California Medical Center
San

Francisco. California 94122

Dear Ed,

interested in the catechol amine theory of
Opiate dependence, and read your 1969 NRC report with interest.
In discussing the possible mechanisms with Doris Clouet, the
reed from your review for her book, and I am writing to ask if
you can make a capy of this summary as well as other relevant
reports available to me.
I have become

Your data suggests that serotonin antagonists, like
cinanserin, may reduce opiate dependence (and opiate drive?)
in post addicts, and if this is possible, it should be tested
in men. Have serotonin antagonists been given to post addicts?
With what results?
Many

thanks.
Sincerely yours,
Max

Fink,

%

D

Professor of Psychiatry

Mszp

�</text>
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