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                  <text>November

4,

1969

Dr. S. Clyde Strickland

Merch Sharpe 8 Dohme
West Point, Pennsylvania 19486

Dear Clyde,

Since 1966 we have been active in assessing various
treatments in Opiate dependence. Rather than relying on
clinical criteria alone, we have developed the technique
of progressive heroin challenges to determine the duration
of methadone, cyclazocine, naloxone, and now centrophenoxine
in treatment.
At the recent methadone conference I was reminded by
Paul Blachly (Portland) and Jerome Jeffe (Chicago) that a
long acting form of methadone has been resurrected from

laboratory shelves for clinical trial. They suggested that
may make new supplies of the active forms of e long~
acting methadone available for study.

nerck

Our recent studies indicate that presently available
methadone is effective against 25 mg intravenous heroin

(-

$15~25

be of

When

street heroin) for

hours.

such compounds are available for

interest to test

My

60

them in

this

model.

trial, it

would

best regaras.
Sincerely yours,
nax Fink, M.D.

Professor of Psychiatry

MF:kp

cc:
3110.

A. M.

Freedman

�</text>
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              <text>Correspondence to: Strickland, S. Clyde</text>
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              <text>1969 </text>
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              <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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