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                  <text>....

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July 9. 1969
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York Modical Collogo

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ROOM,

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Profoaaor and Chair-an
nopartoant of Payohiatry
5 Eaat

Now

lOan Stroot

York.

Now

York 10029

Door Al.

It givoa no groat ploaauro to trananit tho oncloood roport
of atudioo cooplotod by our third yoar roaidonta during thoir
oloctivo in Biological Paychiatry. 1968-1969. Dru. Richard
Abrooa, Rohort Lavina and Michoal Taylor hora boon unusually
productivo.
Tho ropOrto rotloct divoroo intoroota. Bra. Taylor and
lovino have collaboratod in atndioa of oar rotio and ochiaophronio.
Ihoir firot roport. "Tho Intoractivo Effooto of Matornal Schiaophronia
and Oliaprins Sax" haa boon publiahod in Science (164: 723-726,
1969), and a aocond. "Pnorporal Schiaophrooia - A Phyaiological
Intoraction borvoan Hothor and rotua" in in proao in Biological

.,

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Po chiot . You know that thia work rocoivod ouarda both locally
Nov York lonrological Socioty) and nationally (A.B. lonnott
Clinical scionoo Award of tho Bocioty for Biological Paychiatry).
Tho atudioo hora boon follouod by an additional report on "Tho

Influonoo of tho 8a: of Hoopitoliaod Schiaophronica on Thorapoutic
of Ronroloptica" which haa boon oubnittod to tho
Bullish Jaunnal 0‘ Rsychiattg. Ho hora ainco proparod otudy
protocola to contirn and oxtond thoao chaorvotiona by oooaya
in tho thorapy of achiaophronio.uith penicilloaina and with

Dooogo Loyola

atoroida.

Dr. Abra-a haa collaboratad with anobora of tho ataft in
atudioa of nnilataral convulsivo thorayy, confirming tho difforoncoa
in nooory function and aioilarity in clinical roaponoo to bilatorol
convuloivo thorapy. A opocial loatnra of thia work haa boon tho
dotinition of oaynaatric BEG pottorna which aro rolatod to tho

difforant hohowioral roopanaoa.

'h’u‘h.

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Dr. Freedaan

July 16, 1969

earlier studies of the California I scale as a
of
therapy choice in mental illnesses , Dr. Levine
predictor
examined the role of socio—psychologic factors in the diagnostic
and therapy practices in our psychiatric service (Effect of
Social Attitude on the Ireatnsnt of Psychiatric Patients).
Based on

also replicated a study of the effects of Cogentin
on both EEG and behavior of psychiatric patients receiving
convulsive therapy, observing that this anticholinergic drug
He

slow wave activity following EC! and elicited
m
the pre-treataent behavioral syndrome, suggesting that cholinergic

reduced the

activity increases during the inter-ictal period of
reported is to be completed.)

301‘.

(This

viable experimental view of the precipitation of anxiety
is encoapassed in the lactate studies of Pitts and Molnre
(New Eng. J. Med” 2778 1329-1336. 1967). Dr. Taylor replicated
their study, verifying that infusions of lactate precipitated
sysptone in anxiety neurotic patients and not in nomls; and that
these precipitated synptoes can be blocked by intravenous calcium
The study was extended to demonstrate EEG changes with lactate
and to pioneer the use of this nodal to define the activity of
new psychoactive anti-anxiety drugs (the Precipitation of Anxiety
Symptom by Lactate Infusions).
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These are only a few of the studies that have been done.
Dr. Taylor with Dre. Spero and Sisson also coupletsd a review
of the clinical effects of chlordiasepoaids in our clinic,
suggesting that adaptation (tolerance) does develop with this

drug.

“I“

(CUMe "imp. Rue, ,139‘1‘,
“.3
mush“
Abrams also completed "A Manual of Convnlsive Therapy"

ha.

1969). Dr.
which described the
and

varieties of techniques for inducing seisnres
is being distributed to residency training programs in

various psychiatric centers.

year has been productive. challenging and stimulating
and ny associates join no in expressing our appreciation for
this opportunity to participate in the training program.
The

Sincerely yours .
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4.,

.lwmwfwaﬂﬂm'rr

Fink, um.
Professor of Psychiatry

Mar
M! :kp

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              <text>Correspondence to: Freedman, Alfred M.</text>
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              <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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