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                  <text>w

w

:w-—-

(IIIwrﬁwﬁm‘nmwvwvvldnwv—mraa

20, l969

TO:

A. M. Freedman, M.D.

FROM:

Mo

SUBJECT:

Collaborative Project with Dre. C. Miras and C. Stefanie,
University of Athens

DATE:

May

F‘i‘nk' MOD.

'Avgr‘I-WN‘W

mﬂ-‘wmwmwhwpfmwfuir-V'IVW-w-Ir

V‘r—-

w”

-———~w

-nw~w‘

Attached is my report of the facilities at the University of
Athens. These are ideal to answer certain important public health
problems.
Do Chronic marijuana users exhibit a syndrome of
organic mental changes related to this use?

Can a withdrawal

characteristics

What

state

be Induced?
in behavior and in

What
EEG?

are

its

are the physiologic and neurophysiologic
smoking in these subjects?

effects of marijuana

relationships can be defined, and
are these related to differences in response?

What dose

Assuming radioactive THC may be used in man,
what is its distribution and fate in human
tissues, compared to available animal Species?
in View of the active Public Health and Department of Justice interests
in marijuana, it may be appropriate to undertake a pilot study this
summer. Funding for a trial would include:

�.W

rwwhmw-WVWv-u-

-

W‘Plvr»

Dr. Freedman

~2—

Personnel

May

Supplies

U. S.

Psychiatrist

Greek

Psychiatrist

(SIBOOO/yr.)

5

20, i969

Salary

Travel

-

$I000

2,500

Maintenance
$

800

~

—

Laboratory Support
‘

Chemistry ($2000/mo)

$4000

-

—

-

(SiOOO/mo.)

52000

~

—

-

EEG

Travel: Additional for
2 American Supervisors

$2000

Volunteer fees

$l000

Telephong! cable

S

300

$7000

contract request

5

2500

$3000

S

800

be negotiated with the NINH (Dr. Yoiles);
and failing that, the Federal Bureau of Narcotics and Dangerous Drugs, the
Ford Foundation or the Foundation's Fund for Research in Psychiatry. Since
an NiM‘i contract is more likely, i would suggest we call first, then write
to Dr. Yoiios promptly.
Such a

may

This'hontract" is best presented separately from the proposed Kaéler-typo
application, although collaboration with Dr. eras should be included in that
application. This may present special problems and could best be handled
as a separate, concurrent application, possibly even one submitted through
the international Association for Psychiatric Research, which may be more
flexible in its fund management than the College.
Mszp

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