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                  <text>Msy

25, 1969

Dear Alex,
By now you should have received my note shout my
visit to
Athens and Bro. Mites and Stefania. The remainder of my trip was
as interesting, if not meta so, than tho first part. The meetings in
Liege were exoellent, with some presentations by biochemists and
pharmacologists from scsndioovis that were relevsny to our interests.
Much of the emphasis was on dopamine and noradrenalin, however,
,and in one discussion, when I asked about the role of acetylcholino.
I was told that it was indeed important but that the absence of a

suitable biochemical assay bed limited the studios to the oeurohumors
that could be studied easily. (Thio was also stated by Dr. Eunnoy of

EIHH who

spoke

at our College this post week.)

I so still interested, however, and so taking the opportunity
to enclose coma reprints of my studies. It seams to me that the
convulsive therapy is the most specific and the best treatment of
severe depressions in men; and that the study of its central effects
should contribute so much or more to our understanding of deprassion‘
as the study of other oeurohuoors affected by imipramino and MAO inhibitors.
In my earlier review I was impressed with sostylcholine, but this
may have boon related as much to the available studios so to any
relevant theory. The same study should be applied to the other
ooutohumors, especially oorepinsphrins and dopamine.
are treating ospreseive patients with induced convulsions,
and bilateral elect rode placements. There are
significant differences in EEG and in memory effects of the two types
of treatment, and while those may be principally matters of degree rather
than kind, it does.provide tho oppoortunity to study two éiffetent
CS? psttsrns. we should be able to obtain CS? before and during the
treatuont process.
We

competing

unilateral

‘

.

Have a good time in Greece. It is possible, though remote.
that I may be back there in August. so pleaoo send me your Greek address.
If not, perhaps you will write when you return to Chicago sad we can

discuss thui further.
Agsin,

my

thaoks for your

»

hospitality.
Sincerely yours,
Max

Fink, M.D.

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              <text>1969 </text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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