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                  <text>December 27, 1968

Dr. E.S. Paykel
Yale University School of Medicine
New

Haven. Connecticut

Dear Dr. Paykel,

I have recently read the report 'Trial of Imipramine
Patients' with considerable interest.
In re«read1ng the retort, I eannot find the data of the clinical response
of the subjects, 1.e., t*teets for the poat~pae drug conditions
for the behavieral measures. Table III indicatea that the differences
between drugs were not aignifiaant-~ but did the drugs affect the
clinical symptoms in the dosages given?
and Chlorpromazina 1n Depressed

appeared elsewhere, and if so, I
the tables. It may be that tha
the drugs or the sub—groups may
clinical change. partially related
to the dosages of chlorpromazine and imipramine selected; dosages
which you indicate are much lower than our own.

this ﬁata has
grateful far a copy of
lack of differentiation between
have haen the result of limitad

would be

Perhaps

It was a pleasure to read the report, and I look ﬁctward
to hearing of equally interesting studies from New ﬁaven.
Sincerely yours.
Fink, M.D.
Professor of ?sychiatry

Max

mil

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              <text>Correspondence to: Paykel, E.S.</text>
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              <text>1968 </text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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