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                  <text>September 26, 1968
Dr. Alain Sanaeigne

Squibb International
460 Park Avenue
New York, New York
Dear Alain,

Enclosed is a final copy of the report "Depot Pluphenarine
in the Treatment of Psychosis in a Community Mental Health Clinic."
we would be pleased to have you conaider this for publication with
the other reports from Sitgea. In the event that this publication
is not forthcoming or inordinately delayed, I would appreciate your
release of this draft for aubnieaion for publication elsewhere.
As I indicated to Dr. Morkel. we are discontinuing all
administration of fluphenarine decanoate and are transferring
patients to the ananthate form. he soon as the transfer is
complete the remaining supplies of decanoate will be destroyed.
As you know, fluphanarine enahthata is now available for clinical
use in our Center.

again, I want to thank you for the opportunity to have
and to provide both our Division and the
Department with a new and useful form of treatment.
Once

carried out this study
my

beat personal regards.
Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max

MF:kp
013C 0

P.S.

I think if you read this draft carefully you will find
that the difference in incidence in extrepyramidal
effects is probably as much related to dosage problems
as to the drug since we believe we used too high initial
dosages too frequently in the early (FD) phases of the study.

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