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                  <text>September 30, IQot
Dr. Carl Salzman
National Institute of Mental Health
5454 Wisconsin
Chevy Chase, Maryland
Dear Carl,

data.

that

HIP

Enclosed are copies of sample out—puts of our laboratory
These samples are selected from the butaperazine study
we recently completed. The output is based on the l966

laboratory data scale.

In working with that form for the past year, we have learned
both that there are important omissions, and that the form lists
many tests rarely or never performed. Based on this experience,
we have modified the form and enclose our sample copies of our

present effort.

I would ghke to suggest that duplicate outoputs and
laboratOry forms be sent to the ECDEU investigators and that
this become a subject for discussion at a meeting of the
investigators. In the event that any investigator or you
would wish to have a demonstration of the application of the
form to a definite set of data, we will be pleased to supply
the test forms and carry out the analyses.
I am

also enclosing a reprint of the controlled laboratory
As I
my associates and I completed in Hissouri.

study which

indicated, I have been concerned with the seeming peremptory
dismissal of iproniazid for the alleged effects on liver function.
The data is not too clear in this regard and much of it is
without sufficient control. If a central laboratory review
were established for a variety of new drugs, for standard drugs
and for different pOpulations under no drug conditions. then the
experience might be broad enough to provide a firmer basis for
such decisions in the future. he would like to suggest that
such a record facility be established.
Ron

I look forward to visiting you, Jerry, Bill Guy and
Sonata in hashington. hopefully on October l8. My best

regards.

Sincerely yours.
Max

Fink.

M.D.

Professor of Psychiatry

Mszp

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              <text>1968 </text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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