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                  <text>m.

J'V'nvy

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7
A

‘

‘1‘-”mew'r'

-.

.

as.

Leo Winter;

New

York,

.July 17;

JrQ, President]
130 Winter Associates, Inc.
211 East 43rd Street

a;

4,"..-

n.

-_,._.u.

Dear

:w-Wnrqwr

New

York 10017

Dr Winter:

'rI have read the date onnghezoxine (hiker ~5738),.with a
great deal of interest. As! is usual. for such presentation,
game of the essential human data which provides the basis for ,
the remndetim that the drug be essegsec! es “en {anti-depressant

.

-

.vn-smr

is. ledcing .

v
-—

vuﬁrrrﬁ'"

flaw-Acme

am

.v—w

I

have read most oloeeiy the

initial

'

We

ere'ihterested in assessing

'

oanpouhds 'of

With regard
barbiturates and
With regard

‘

,

”aqua-312m:

viva-3v

Wm.

.
way-r

~7r—uWr-nrnwww—vv

wave-9*?

mum-true?

qmmum.wmn

Qkun and

and

Baltes

this class.

'

'

Mohhemayhavegumitted.' "

...

data reports

Before undertaking a review of a protocol, I would. ask that
of the additiohal data available to you be stared with my
aesociateg and myself. W5thregem! to Carl Pfeiffer' 5 date, I
wand be interested in transport itself and any Em samples
game

‘
.

;:-

hmnan

particularly interesteq in those of Pfeiffer,

(D02; 005);.‘

,_

«;

1967

'

E

,
g

his method been applied
similar’
or different?
30, 183438

to Dr.

if

'

'

Ohuh. has

'

to Dr Balms" study

to

002-, he may have concluded
1

that. Ila-7.38 Ind some ahtichinergio activity. Is this true? In
his other studies (00% 906)17the date is Measures to wluther
depression and stimlant mivity occurred in the same Subject
or .different and whether he interpreted the data as eonsistent
with an antidepmgsant,
’

....

'

'

'

'

=

.

My

present laboratories.

heVe two

populations available - the

mre usual out—patients. of largely a lower. class origin, emiihiting
treicarqplex psydwtic and neumtic (iiegmeeg. In addition, were
is e specialized. population of substance abusers , mostly nmotic
addicts who provide” the basis. for epeeialized studies of new corpounds
which may be useful in; the treetmnt of substance abuse. I am
_

’

va

«wan .- mlu-

�It
or, Winter

«2»

'
.

July 17,

1967

particularly interested if: central nervws system stimlants and
change which may have an antidepressant quality, since clinical

depression

is a mun manifestatim of narcotic addiction .

In addition to clinical studies , we have been interested in
the use of the electroemephalogmm as
an index to new
studies .
It is for this reason that I am particularly interesteddrug
in the data
collected by Carl Pfeiffer.
‘

'Ihank you very much for the opportunity to read the data of
fenazoxine. If the additional infatuation is available , I would
be pleased to meet with you after we have had a chance to read
it.

Sincerely yams ,
Fink, M.D.
Professor of Psychiatry

Max

Mftkp

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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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