http://exhibits.library.stonybrook.edu/mfp/files/original/9c89fb0a03822ceaf83aa75e0b25f8ab.pdf 5d2c231c569267d6b6684a8de5944e26 PDF Text Text 5 I . ”viva”, .VV._;.,.,.,. 3...... {Yr—”u... ,.., u, » June 20, 1967 u w“...- wwmmm <- vw-v—wn Dr. Jmsthan 0. Cole, Chief, PR3 Barlow Building Avenue susu Wimin Room 10C01 Chevy Chem, Maryland Dear Jonathan, I ' as: Isl-1256742 - uniting to request your permission for the allocation to $3, 700 from Mil—12567 to support special animal pharmacology studies of cyolazocine by Dr. Richard P. Irmite of the University of Termssee. am of fmds The up clinical studies with cyclszocine in the treatment of narcotic addicts have gone very well. The initial studies denomtmted a satisfactory dosage schedule and we are new cyolazocine oxgmizing the comparative rs‘ndm methadone transients in volunteer narcotic addicts. Concmmntly, our EEG assth studies demonstrated a spectrum of activity similar to imiprsmine and a clinical stung of cyclasooine in the of depression undertaken in St. mum. The results of the first eleven depressive patients are being presented at the Montreal ECDEU meetings, and mess demnstrste clearly that Cyclezocins has antiéspressant activity. At the same time, we have hem studies in the Mental Hygiene Clinic at Metropolitan Ibsfiitel and these too are showing unusual clinical results. mm " Under project WI~13358, the EEG latmtory in New York is re-established for quantitative analysis and I am devoting the next few mnths to an intensive analysis of the dose response of cyclazooine and heroin in postmamotic addicts. The animal studies of heroin and cyclszocine are very limited. Dr. Richard P. Emits of the University of Temessse, a. sophisticated aminel phamecologist, with a sincere interest in EEG, has indicated that he would be willing to carry out some additional studies in his laboratory during the next's to 12 months. He has some time available because the proposed sabbatical in England has been deferred for one year since Dr. Bradley is to he may in Palo Alto. m �:a4 law) 1..., - 4v» ~ -.- m“. Cole A A ~2- June 20, 1967 -‘ , My”... .4“ ...,_ "Wu—v”; -.1—wwvmp—g-.~ After some discussion, Dr. White has submitted the attached protocol and has indicated that these studies could be supported by a budget of $3,700. This own is available in the present grant by the transfer of personnel costs to our clinical funds . Dr. Preednan has concurred in them mmndations. Play we have your approval for the allocation of funds up to $3,700 from I‘m—12567 for consultationtfees to Dr. Richard P. White of the University of Tennessee in line with the attached protocol? ‘4 "< V- Many ‘ - z-r ' ; thanks for your assistance. Sincerely yours , :v“?-w-<". . pmwmmwwxlquv-m Pink, M.D. Professor of Psychiatry Max, MF':kp cc: Dr. White ' zen": W'Wwa aammawww. 15v ".79.". -; n u» .r. uranwm. -».- .. , u . rmrw4lr-lufii � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Cole, Jonathan O. Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-021-5-245 Date A point or period of time associated with an event in the lifecycle of the resource 1967 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence