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                  <text>February

9,

1967

Dr. Richard Abrams
10%

Childress

Sheppard AFB, Texas 76311
Dear Dr. Abrams:

I have read your letter and your report with interest. I
found the review of focal seizures quite good and you confirm
the need for a definitive EEG, behavioral and
study. The

my

data demonstrates clinical equivalents for unilateral
and bilateral BUT, the more important a definitive study becomes not only for the practical aspects but the theoretical as well.
For this reason, I regret very much that the EEG material
was not collected. However, you indicate that you may be able
to collect EEG records in the remaining subjects. If this is
so, for comparability it would be very helpful to have records
collected 2M to 30 hours after a seizure so that comparisons
can be made with my earlier studies.

more the

In reading the paper, which appears to be mislabeled, I am
impressed with the equivalents of the mennry tasks. However,
why were the clinical results not included? Surely, since these
patients were receiving treatment the records must show whether
symptom relief occurred, or whether there were changes in global
aspects of behavior, or whether there were some other secondary
effects, Perhaps you wish to wait until you have completed the

additional thirty subjects. But if you believe that this data
is sufficient for the menory results, it should be as sufficient
for the behavioral data. Incidentally, I think the title should
more properly be related to the detailed analysis of memory
changes than as a general statement of the daily administration
of unilateral BCI‘.
In your letter you indicate hat you have collected the
data at each five treatment intervals. It would be
helpful to exandne these as carefully as the results after

memory

twenty

treatxents because

give an idea as to whether
it will
two
differ.

the rate of change between the

groups may

'

�-2-

Dr. Abrams

he

February 9, 1967

Your question regarding Dr. Abood

is

either interested or has the

is

good, but

I

doubt

that

facilities to undertake these
clinical and our experimental

However, cnoe the
aspectsaredefinedIoancallsaneofthepeopleinNewYorklﬂce

deteminations.

Dr. Abood.

literature review sounds good and I will make available
to New York. As to the statistician who
my files
can perform the tests you require, if you will lay out the numbers
on sheets identifying the variables, I can try to get the work
The

done

in

when you come

New

York.

I have recently re-read the BOP studies of Dr. Paul Blachly
of the University of Oregon. He describes the administration of
multiple treatment in one day with EEG control and argues that
with proper ventilation the memory changes are minimal and the
clinical improvement enhanced. He has a single report which
appears in Compaehmiue PAchy, Volume 7, g: 100-107, April,
1966. As part of your reading I suggest you become acquainted
with this article. He too has theoretical suggestions which
warrant testing.
Keep up

the

good work.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

,

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