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                  <text>Pebmary

2M.

1968

Br. Craig D. Burmll
Meal Services Director

muticala
Jersey 07936

Sande:
Hanover.

Dr.

Dear-

Now

Emil:
Itil

Fallowing yum letter of Jammy 21, Dr.
and I mqmsted
Dr. Holden to review the data or: those patients who had rammed
an thior-iduim or
ﬂaioridazine and dulordmmpoxide for
estimates of the prolonged changes in hemoglobin.

mm

5Wof the average Mmglobin
Within
sway
vﬂmsfuroadaofﬂnsubjcminﬂmstudydurin’geamofﬂm
Dr. Holden has submitted
February 11.

and

patina. In the

W

statements.

The

first,

plambo',
3mm
daaIma,mthVisthioz-idazimalmxe
dnina
anddmgIIisaeombinatimcfﬁxetw.
drug

w

statemnt, dmg II is

forhemglobinmd
mmngivommmvalms
far the eight patients who were maintained m «timer!
WW1:
the cmbirution or placebo beymd the study period. WWely,
this group of patiantzs appears too small to contribute to m
undamtmding of the hemoglobin
with Nor-manna .
Sinilmly, fbn‘tha

W
We in Whoa-it.

Howevur, them have been additional measurements made of
hauntocrit. homglobinanddmmgesinmight. Theseappawon

ﬁnfoursubsaqmntpagas. MemtatimafordrugsII,IIIand
Nmﬁusmasinﬂmprwimmamy. Minamtocritand
hmglobin m the diffomnt moms between the masuremnts

dimingﬁulutfiwweelmofmiastataaperiodandmpmvious

dmgperiod. Inthisway.thefimtm1mnofﬁuhmtocritmd

Wtdmccmbemadﬁmtﬁnmtocritshomda2gmm
diffmmbomnﬂmdmgﬂ periodmdﬂmepmmdingtmmm
pagodforﬁsaubjeetmdmmnﬂythaweigﬁalm
by
mud: mmperioda‘.0mangdmgﬂwiththev:
pmoadﬂudmgﬂperiodmcwﬂlmforﬂxispatimtmatthe

thmdbylmmﬂnmighthmmdbyTpom.

�m. Craig D.

Emil

Hazwver, New Jamey

~2-

man the patient waived drug II again the hematocrit increased

byagmamdﬁnmightdemwedbylpmmd.

Reviuwing this data it seem that there is an inverse relationand Mmglobin on the one hand
ship between dung“ in
and weight on tha other. As the hmtocrit and hemoglobin demand,
the weight increases, and (mammal)! as mmtmit and hemglobin
the weight falls. Pom, the marked changes in weight

Weak

We»,
mﬂeetﬂnmmgaa inbodyﬂuida. Mpossibilityothem—

dilutim being a factor in the damages in hemtocrit and hemoglobin
is an interesting idca, al‘tmugh I would be Miami!) expressing
this generally.
to

We have not yet heard from our cardiac omsultant, but hope
have some data shmly.

Imttl'ﬂaisofintemstmyw.
‘

Simemly yams,
Fink, HID.
m
Pxofessor of Psycmatxy

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              <text>1966 </text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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