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                  <text>Dsoember 23, 1955

Dr. Neonattin Polvan
[martin Cad. 8mm Apt. 17/1
Taksim

-—

Talinham

Istanbul, Turkey
Dear Hr. Polvsn:

I regret very mush the musual oomplioatims with Dr. Crane.
that he would be able to make a site visit and
It
provide a visual image of your facilities. However, since there
are now very heavy restrictions in mm grant wards because of
the oomittments of the war in Viet Ham, I believe the best
strategy would be to mdertake a pilot study using such funds as
you may have available and attempt to obtain sou-1e small support
from plummutioal houses. It shmzld be possible to select
oummds which are still of interest to various drug companies
was our hope

TA

-A.

.

law”.--

uu'f‘wwwzerrl

»-:-anm-

sothattmymaymakethedrugsavailableatnooost.

"WWW"

letter you raised three questions. lbs first ,
the
testing of new «rounds in untreated schizophrenic
relates to
This
is a very important question and if you were
patients.
interested in most-taking studies of butaperusine, for owls ,
this study would be very Mlpful in answering questions which
In your

wm'.lwtc.Au-v

mpuszlingtoday. mismdisalmadyaooeptedinfimpe.
"new”

uncover, you were interested in testing
minds,
there are my that have been momtly proposed which we are
studying here. Parellel investigations mderteken in your
(Pfizer)
facility and in ours of such oanpoma as thiothirene
would
both
(Squibb)
enmthete
the
fltsabenuine
noting
long
or
be supportable studies.

If,

~—mW~chr4'erijwrrr4-1W

lbs second question, whether schizophrenia is reversable,
is a very ignorant me. Hmover, it does not lend itself to
an early simle mower. If we are anxious to obtain support
at own future time, it would be more helpful to mdertake a
study of shorter duration.

.

third question, of activating chronic schizophrenia
by hallucinogmio drugs, is a study which also has much merit.
However, we have many chronic schizophrenic: patients treated
Your

_

wpwv._r,,wnm,f

m,”

�Ir.

Polvm

-2~

December 28, 1965

for long periods available and such studies are

in progress hem.
Ifyeueouldmdertahetwopmm—thestudyofnewdmgsin
untreated schizophrenics and a semnd study - then such activation
projects would be of merit. Perhaps they should be planned in a
fashion parallel to our present pmjeete.
mm

-

-

mileyouesktheeethreeqmtima,my1poseefmmﬂﬁ

are the effects of new drugs in meted depressive cases?
Is them a difference in treatment results between: psycmtzwic
drugs and ECT in mtreeted depmssim? These two questions
mounting mtmeted depmsaives parallel the questions asked
in the drug and schizophmie study. me results of these studies
aould be of help in substantiating the value of such a study unit
What

Ietmbul.

If

any

the next

few weeks.

forﬁueﬂewYear.
Myouverymdlforyourkindmgm
wife
and
my best wishes for
Happy

Fleece

and

we mld be pleased
and working out the details in

of these projects interest you,

to assist in planing the protocol

mp1:

Prospem

1966.

you

your

for a

Sincerely yours ,
Max

Fink. Md).

Professor of Psymietry

MPucp

�</text>
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              <text>Correspondence to: Polvan, Necmettin</text>
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              <text>1965 </text>
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              <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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