http://exhibits.library.stonybrook.edu/mfp/files/original/c0f523564106685f5802ee04b85b5bc5.pdf 04174893e630fecafe177c91e30d9ff3 PDF Text Text . July 20, 1965 Dr. Alfred M. Freedman York lidicel college 5th Avenue at 106th Street New York, Hm York 19029 New DeerAl: I do Inpeymrtr'iptommpe m esuooeesful one, despite the treneetlmtio telephone oella which you rent have received became of the homing problems in the Depertnent. I an in the midst of completing a report on oholimrgio in convulsive timepy end while reviewing the literature, om eoroea the moloeed two articles which brought mechanism to mind the usage of possibilities for studies in the drug addiction populatim. Reno, e1: 111, reported that a single dose of norphim inoreeeed oe‘fibfil eoetyloholine in mtmeted mimele, huthednoeffeotinohmniomorphinizedmimle. The oholineetemee activity appeared to be the some in both sets of animals. They concluded that eoetyloholine metabolism in brain may be involved in the mediation of demlopment of toleranm to morphine . This observation is of special interest when joined to the cursory Rueeien report by Denisenko who remanded central oholinolytio agents for weakening the dew/element of tolera‘me to mphine md its substitutes. From our point of View, we know that cholinolytio agents produce EEG deeynohronizetion. It is also probable. although for from pmven, that drug addicts tend to develop highly EEG patterns Ming the course of dependence . these observetime warrant further study. it would be If advisable to replicate Dmieenko's report, with EEG omtrols. eyndxmnized Iwillbe ooufingEest formyveoetiondm‘ingmguet and will take the liberty of oelling your office after you have had eohmoetoedjuettohewYork livinginAugust. Hybest regards. Sincerely yours , Fink, M.D. Professor of Psychiatry Hex enclosure � Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correspondence to: Freedman, Alfred M. Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context mfp-05-00-019-5-427 Date A point or period of time associated with an event in the lifecycle of the resource 1965 Creator An entity primarily responsible for making the resource <a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a> Subject The topic of the resource Correspondence -- Correspondence Relation A related resource The Max Fink Collection Description An account of the resource Rights Information about rights held in and over the resource <a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a> Source A related resource from which the described resource is derived Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York). Language A language of the resource en-US Format The file format, physical medium, or dimensions of the resource application/pdf Publisher An entity responsible for making the resource available Contributor An entity responsible for making contributions to the resource Correspondence