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                  <text>Homer u,
Dr. R. Cooper
Burden Neurological

Bristol, England

196:;

Institute

Dear Dr. Cooper:

It was

a pleasure meeting you in Santa Fe. As I
left with Grey Walter, we had the opportunity to discuss your studies with implanted electrode and multi—
focal frontal leukctomy in psychiatric patients.
You may

recollect that during the meeting

Dr.

Brazier's paper was read and she reported finding spike
activity in certain depth electrodes when surface elec—
trodes dmmstrated a desynchronization of rhythms. Her
surface frequency Spectra clearly demonstrated patterns
midi were remarkably similar to the results of the
intravenous or oral adnu'nistration of imipramine.
In your work, have you had the opportunity to
administer imipranﬁne to one of your subjects with depth
electrodes in locations similar to those described by
Dr. Brazier, and if so, are the observations in the

public

domain?

I would be grateful for copies of your reprint
in this area especially that of the Journal of Neurology,

Neurosurgery and Psychiatry of 1961.
Thank you very mch

for your cooperation.
Sincerely yours ,
Max

mf ; ls

Fink,

Director

M.D.

�</text>
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              <text>Correspondence to: Cooper, R.</text>
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              <text>1964 </text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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