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                  <text>July 1,

1964

Miroelav Posedel, H.D.
3950 Kelsey Place
Colombia 4, Ohio

Dear Dr. Posedel:

for your inquiry. The Missouri Institute of
Psychiatry is the research and training center of the Division of
Mental Diseases of Missouri. It was established in October, 1962,
with laboratories and clinicsl facilities for research. At the
present time, of 150 beds, we are utilising 70 for research pur—
poses. Laboratories are established in pharmacology, psychology,
and electroencephalography. as well as a computer center for both
Thank you very much

statistical and BBC analyses. There is a specialised psychiatric
reseerch library as a component pert of the Institute. Animal
facilities are now being built and will be completed by the end of
the year.

there are a number of research programs in
progress. These include Lithium as e therapy for mania; the use
of Yohiubine an a precipitant of snxiety and the deveIOpment of
anti-anxiety agents; relation of EEG patterns and organic factors
in the treatment of therapy resistant psychotics; computer analysis

At the_present time,

of the electroencephalogram; the effects of drug withdrawal on
behavior in the chronically ill; the evaluation of new psychotrOpic
drugs is part of a national early clinical drug evaluation program.

.c‘

..v.‘--.,.oq-,~.

.

In neurophysiology, we have the following major programs: evaluating
the 330 changes with psychotropic drugs and relating these to the
behavioral results; a study of the cortical averaged evoked potential
and determining the stability of this method in our patients; and in
determining the interrelationship between different methods of EEG
analysis and efforts to quantify these, and to relate these changes
to behavioral changes as reflected in psycholinguistic methods.

m,—

awdqfw

wiw

At the

present time. the Institute is planning to expend these pro~
We are inviting the collaboration of scient-

stems in the coming year.

ists

whose

intereste are compatible to our

tunity such as this institute provides.
applications.

.
..

A

"mas-Farmy—

own and who wish on oppor~
and are pleased to consider

�Miroslav Poocdal. H.D.
7-1—64
Tho

Pas:

I

uuuld apyrnclata a copy_o£ your curriculum vitae. listing
chronologically your .ducatlonal and professional experience.
In addition. a small photograph and thc n1mea cf at least two
rcferuas to whan us may write would be moat helpful.

Sincercly youro,
Mu Pink, Md).
Dirnctor
luv/1b

�</text>
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              <text>Correspondence to: Posedel, Miroslav</text>
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              <text>1964 </text>
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