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                  <text>April 17,

1964

Dr. Max Pollack

Killsids Hospitsl

Po 0s 30! 38
Glen Oaks, New York

Dost Msx:

is the history and present ststus of my attsmpts to discriminate bstwnsn schizophrenics sud depressivss, using the EEG frequsncy

Tbs folluwing

snslyssr dsts.

Estly lsst winter. John Stern ptssentad a paper in St. Louis showing the
diffsrsucs batwssn achisophrenic patients and s control group, in a cross
torrslstion analysis of EEG signals. His study was wall dons sad it canfirnsd the findings of Kennttd. Partly as s lstk, we obtainsd s distrimin~
sts function snslysis for tbs lib pstisnts, using tho EEG bands of delta,
theta, stc. The F ratio was 3.08. with a significant P at the .01 lowsl.
Hhsn looking at the discriminate function cosfficients, the dsts bscsns
quite pussling. Tbs msjor tantribution was wads by delta activity sud
bets two. Howsvst, instesd of having an increased snount of bsts and
lsss dslts in the sehisOphranits st every ans sxpacted. our dsts shownd
that tbs schiIOphtcnit group had more delta sud lsss bets tﬁt thsu the
deprsssives.

that point. I called and asked that you send us the records of the
pstisnts who wsrs st tbs two entrants of the distribution.

At

42

Reviewing ths diagnoses, it beeswc obvious first that of the first 25
patients at the schisophtsuic and of the diserininsts functien analysis.
9 had been lsbslsd childhood schizophrenia, and 8 undifferentistsd schizophrsnis in our early elasaificstious. The asst age for ths 20 schizophrsnic pstients was 22.9. and the meta ass for the E0 dsptsssivss st the
other and of the snslysis wss 43.5 years. Thus. tbs diffsrentistion was
not bstwtsu sthitophrsuis sud its dtpretsion, but childhood schiIOphrsnis
sad deprsstivs disordsrs.

Nsvsrthsloss, this was not s sufficient explanation so I asked Dr. Itil to
rswisw the_rstords with as. we snalytad such record scaording to the form
ontlotad with this lsttst. The records were placed in alphabeticsl order by
my sscretaty, and ws disrsgsrdsd the nets sud sgs of ths subjact. The records
wars tsviswsd. sspstislly the tasting psriad, the psgss analysed by the
frsqusncy analyssr, syn—opening sud sys~closurs. and hypervsntilstion. When
this wss done. the dsts wss summaritsd according to tha rstssrch diagnosis,
thst is, dsptsnsivs disorder, childhood schisophtonis, sud schizophrenia.

�Dr. Ha: Pollack
4-17—6‘

Page Two

Thsre were 12 doprcsslvos. 9 ohlldhood schisophrenlcs, and 21 achlaophranlca
among the records which you sent‘ne.
Following this analysis, chloh I will summarize lo a moment, wo further sub—
divided tho achiaoyhraolc patients into those who wore 25 years and younger,
and than: 26 and oldar. Thus, on havo.£oor groups.
Beta dominant records more soon in the dsprasslve patients and the oldar

aohlaophrenlco only.

whlla there were no differences in alpha dominance in the records. there was
a pradonlnsnt number of theta dominant rocords in tho childhood oohiaophtanio

group, and the gunman: schizophrenics.

la the tamalnlng'chatscterlstlcs, the four groups could not be distinguishad.
In reviewing the general rsoarﬁs, Dr. Itll noted that we had much morn alpha
and grastet amplitudas, greats: degrees of synchronisation. than he
was aocustnmsd to seeing in the schizoohranlc gatients in Erlaqgen and that
we are accustomed to oozing to our patients in St. Loulxl no asked if I had
any psychopathologloal~aymptom data for these patlaots. and slots John had
taut ms the $228 profiles. I called those as a rapid approximation of the
predominant psychopathologlc state of our subjects. The sheet is snolosad,
and shes: little differenco in agitation, apathy. delusions, and oven daprssn
alon among the four groups. Indeed. tho only distinctlvn dlffarsnsa appaara
to ha in hallucinations. and those are only occasional to the sohlsophranlc

activity

patients.

His response, and my own from having worked here to: the past two goats. in
to say that tho alllalda papulatlon is an extraordinarily unique one. As no
foané when aux Hamilton roviewod our patients. the sub-divisions into depras~
alva dlsordsr. sohlaophrenla. st¢., are guegsss with regard to the oventual

cutout. a

I

I ballavo this data to be quite important because it shows that can can
daaoaIttats tho diffsranccs bstween the sohlaophranlos and tho dapraaaed
patlants using frequency analyser EEG data. However. the diffsteooos are not
in tho usual dlraotlon and ara relatad to the fact that you hava collactsd a
unions group of brain damaged or otherwise EEG unique patients in this spacial
sample. Sotaly, tho futthat analysis of a largo: group of adolescents, and
tho young disturbad patients. using EEG asthoda 1s raquirad. It was with this
data haally to also. that l ancouragcd Dave Eogslhatdt to contaot you and aug-

gastad that he undartake such a study. Since then, I havo had the opportunity
to most with tho Chlldhood novalooment Rassatch Cantor group under Janos
Anthony. and have encouraged thou to allow an and my aasoclataa to undsrtake
such a study in that: population. Va have our own youth cantor with 50
patlonta, and a study has bean launched in that group as wall.
A

conflrmatlonnof these observations regarding the diagnosis of tho patlaots

�Dr. "‘3 P1311161!
‘-17~64
Pug: Turn:

come from your fellas up data. If the informa‘2
avntltblo for these
tion
paticats. it would he must helpful to know
havu
bcen rohonpienliued; their lator diagnoais. uspscinlly
which, if any.
1f 1: was and: by you: and thair predominant paychapathologieal symptoms
lone yuars after out obsorvation. If tbs: information is avnilable fat
than: pae1¢nca, it would ho helpful :0 clar1£y the pro-ant poultion at aha
ﬁnd

their clinical stat. can
13

Itudy.

not sure what I can do with the immadiata data of thts discriminate
function. I haw: an opportunity 1n-Loa Angola. to diucuua John Stern's
:cpart.n1nd may take occasion than to make some commnnta. Kauuvar. I éo not
know haw ova can pub11sh th1s kind of material ainca 1t nay be a ruflcction
at the uniqua papulatlon chattcteristien of Hillside.

I

am

Thank yvu very much for your halp, and I would be
you can mtka on chain remarks. no you want me to

grttciul for

any «caucus:

return the record: promptly.
am
hold
with to look a: than
than-far sang longar yeriod in case
or may I
Any
other nuggaatiout?
again?
sending Dan the max! version at the depression paper, and
of
the way, I should ltkc to writ: a more formal nunmaty of
is out

Sepsrately, I

whan zhnt

thc

EEG

am

matartal.

Sinaernly yours.
?1nk.‘¥,
Director
Max

2427/5»

Inc.

D.

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              <text>1964 </text>
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              <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
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              <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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