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                    <text>‘lﬂr'r'xr

-

-:

-,._

:r-rvmn-

or-

{If-"nun;

M1:

‘

"Wi‘ruwarmt

rr,

'w-Jr-

733:032

January 23, 1973

Giles, M.D.
N.V. Organon

Alan

Oss, Holland
Dear Alan,

I returned to New York Saturday evening~~ tired but most
enthusiastic with the progress of your units. I am confident that the
center in London will develop nicely under Leo Lange, and an scheduling
a study of GB~9h to begin in April.
Yesterday, I discussed the potential studies of GB—9h and 01-63
with Dr. Joyce Small: I found her interested in both studies and I believe
she will write to Hank shortly, to indicate that she can begin the study
of GI—9h as soon as all the papers are approved; and of OI~63, when she
has developed some tests of memory loss after a single siezure. This
problem is more difficult, and will take some time to unravel.

latter

I have taken the liberty of writing a note to Professor
Vossensar, and to Derek and Hank. I would be remiss if I didn‘t tell
you, that I have already expressed my gratitude to them for their
welcome and to you for your many courtesies, enthusiasm, and soaperation
in these studies. I do hope that you maintain your interest in CNS
methods, for you have a remarkable grasp of the issues, despite your
short acquaintance.
My very best thanks for your tender nursing care. I
I will find in opportunity to reciprocate soon.

my

best to

Leo when

next you

visit

him, and

hope

to Hillary.

Sincerely yours,
Mex

Fink,

M.D.

that

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                    <text>an

-:

.V‘uem'n-wn-w -prqun=umsw~ "n,

Jar-Wm

«mew-«nuns:

ww- \' T‘Y“?“Wi~e' -I:'.'1"" 4-”, ma»... '-'v4~.‘ .7”-

&gt;-—W

—.-~-.——w---.-,&lt;-~,- “ya—vav

W

.

nwr.-..q....

-

,7“.

MW"

1,

733-031

January 23, 1973
Dr. T. Vossenaar

.q

1
H
.

.;.

N.V. Organon

Oss, Holland

"a

,7,

pp,

Dear Prof. Vossenaar,

"vas-

4?"?-

rm

v.3.

3mm

w-.,.

Ina-m7»

”my

I very much chatted my visits to Gas and to London, and
take this occasion to congratulate you and your staff for having achieved
so much in so little time. It was regarding to find that the complete
data analytic system was in Operation; to find that the data recording
system was well thought out and should be operational within a few months
in London; and to have an opportunity to discuss a series of novel and
interstting conpotnds, as GB—9h, 01-63, 01-30 and the many others in the

'pipe-line'.

visit to London, I was impressed by Prof. Lange and his
technician, his facilities, and his caution and Judgement. I believe I
can work well with him, and vs will cooperate in setting up his facility.
In

As

soon as he

my

is ready,

we

will carry out parallel studies of

GB~9h.

are continuing our increasing dose studies of 01—63. I
also have met with Dr. Joyce Small and discussed with her. studies of
01—63 (a replication in man of the memory studies of van Riesen) and
of GB~9h (rapid dose increases in a few days in patients who have
been recommended for ECT). I believe she is interested in both studies,
and has agreed to write to Dr. van Riesen.
We

I have sent the sample or 01-30 to Dr. William Martin at
our national narcotic addiction research center in Lexington, Kentucky.

I should be remiss if I didn't express my sincere thanks to
Drs. Giles, van Riesen, Porsack and their associates, for making my visit
so fruitful for me and so comibrtable. While they kept me busy, I enjoyed
every minute, and returned to New York, somewhat tired, but most enthused.
I look forward to another visit and the results of the ongoing syndies.
My

best regards.
Sincerely yours,
Max

P.S. Because I could not combine this

Fink,

trip with a visit to

M.D.

Athens, I

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                    <text>..,-

Wuxvr—v,v

733:030

January 23, 1973
Dr. H. van Riesen
H.V. Organon

Oss, Holland
Dear Hank,

during

my

brnught back many new thoughts.

Joyce Small flew to new York yesterday, but her plane had
and we could not meet. Instead, we chatted on the
phone for more than an hour. I brought some of your thoughts to her
attention; assured her that I would be most cooperative with my IND,
and when she asked whether she could obtain her own, assured her that
such a procedure could be accomplished with little effort as derivative
from the one I now hold (and for GB-9h, for that one as well).
many

difficulties

.~

We

“'1"

'

WWW'VIWWW

war-x.

i-wywv-Nv'.

.-v-.1

'-““'«&gt;'m-jl""‘"l"

:.
-

:wmr

W

wunmkuv

w—yr

w:m~wwm

First, let me thank you for the many courtesies you extended
visit: a visit which I thoroughly enjoyed and from which I

ECT

discussed the study of

in severely depressed subjects,

should be

GB-Qh

and she

relatively easy to accomplish.

in the first few days before
indicated that such a study

We discussed 01-63, and the replication in man of the
studies already accomplished in the animal in your laboratory. As we
discussed, the problem is not the subjects or the ECT, but the selection
of mempry tasks that would be sensitive to the degradation of a single
siezure. Many tests would have to be done first to establish a prOper
test system, and then it (a proper, sensitive test) could be used in
an assay of 01—63. I have already asked my co-worker, Dr. Dornbush to
outline the tests we have used in our ECT studies, and I will send some
notes to Dr. Small.

She

nor some of the

indicated she had not received the basic data on GB—9h;
latest data on OI~63. She said she would write to you,

describing her questions, her interest, and requesting these documents.

I trust our discussions

our next meeting, in Gas,

New

were helpful; and
York, New Orleans, or ?

I look forward to
7 My best regards.

Sincerely yours,

'rl-V'“

"1

amateur—pr

in:
mm

Max

Fink,

M.D.

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7)

.

..

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,

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73KY-028

January 23, 1973
Mr. James Lewis
Elmwood Hall
New

York Medical College
New York

Valhalla,

Dear Mr. Lewis,

on

it

is no longer possible to set aside funds fbr TIAA
a tax deferral basis. I would upprecitto your cancelling payments to

TIAA

Since

on my bohnlf,

effective January 1,

1973.

Thank you.

Sincerely yours,
Mn:

Fink,

M.D.

Protector of Psychiatry

v

a,

�</text>
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pm

F'vv’rl-,‘p,""v:'4‘vv-

,.\d.f"1n[lpa‘rrmfhs

1w

qr
nu:

733:029
January 22, 1973
Derek Quantock, M.D.

N.V. Organon

Oss, Holland
Dear Derek,

week, but I

I regret that

trust that

we

were unable to meet during

you are

my

visit last

sufficiently recovered to accept

my

congratulations on two accounts: your new position, for which I
wish you all success; and the remarkable progress your unit has made in
developing the methodology of drug assessment. It was a remarkable
achievement which the staff demonstrated, when they replicated our studyof doxepin: the conversion, analyses, and the statistics yielded the same
data which we had achieved. It is clear that your unit in Gas is now
fully equipped to analyse records.

the extent that the first goal set in our initial discussions,
you to establish an analytic facility, has now been set,
we can now take comfort and some pride in setting the goal and its achievement.
In my discussions with Drs. Vossenaar, Bpilvogel, and Overboeck, I was
pleased to bring this success to their attention.
To

that of assisting

The next goal, that of establishing an operational test
seems well in hand. I met Dr. Leo Lange, and visited his
also
facility
You have equipped it well (Mr. v. Lierop is most
London.
in
facility
capable in seeing to the equipment needs) and I am impressed by Leo and
by his technician. We had a fruitful discussion and it should be possible
for him to replicate our methods during the next few months; and for
us to carry out a study in parallel.

I agreed to monitor his development; to agree to a common
protocdl fer the study of GB—9h; to carry out one study in New York, and
to supply a set of tapes for analysis in Gas; and to analyse the London
tapes in New York, so that two comparisons can be made: of the recording
units and of the analytic units.
Finally, on my return to New
Dr. van Riesen of Dr. Joyce
by
requested
New York. I was able to communicate the
of 01-63, as presented to me by Alan and

York,

I discussed the studies

Small with Dr. Small who was in
needs of the studies of GB—9h and
Hank, and I believe she will

�."rrﬁw‘i ,.
,

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v-7

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submit protoclla for your consideration.
This report would be incomplete without a note of
gratitude to Alan Giles, for the many courtesies he showed me, and fer
the planning that went into this visit. I very much enjoyed the discusaions
and hope that I was able to show, by my efforts, how stimulating the
many questions were. Considering the short time he has looked at EEG
issues, Alan is a remarkable young man, and I hope that he will continue
his interest in this problem.

I trust these lines find

you

well,

and hope

that

you

will

be as successful in your new position as you have been fOr Orgenon.
My very best wishes for your success.

Sincerely yours,
Ml: Fink, M.D.

�</text>
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                  <elementText elementTextId="106623">
                    <text>v—‘v

"

"N“ '7 Au" “‘nsﬁw‘rt

was

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73SB~027A

January 21, 1973
William R. Martin, M.D.
Chief, NINE Addiction Research Center

P.0.

Box 2000

Dear

Bill,

Lexington, Kentucky

It

was

hOSOT

kind of you to express an interest in

01—30.

(n-cyclopropylmethylnoroxycodone). I have Just returned from
London enﬂ under seperete cover, am sending you 1.9 grant, for
your evaluations.

Should the compouna exhibit characteristics that
would stimulate our interest in clinical trials, I have been
ensured by the research stuff at Orgenon that they would be prepared

to engage in additional studies and production.

I
,.

hope something comes of

Many

thanks for your

this.

interest.

‘
V

_

...&lt;,

“H.

Sincerely yours,

,.,,

t

wmwrrtxwwrvwghyw

«w

WWW",

”WWWMV-vmwu

Fink, M.D.
Professor of Psychiatry

Mex

V

v

.

�</text>
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                    <text>Docsﬁber 18th, 1972

Jaaeph 1. English, H.D., Prosidonz.

Hetlth and Hocpitala’CGrporat1an;
125 Wbrth

new York

Dcar

Street,

City,

R. Y.

nectar English,
As you know,

the resonrah

1nd

treatnant stud1es

1n apiuto

dapendaneo vh1eh haw! bucn 1n progruau at 1h. Metropolitan
Houyita1 Center s1nc¢ 1961 have been ohJoinad tram
continuation. Since #3 banana 1nteratt¢d 1n phnrancoloz1a
approsehul to opiate dupcnacnae. an extenn1v¢ ser1cs of studio:
have been canp1cbed.1ndaod, it 1. sure ta any that outsidn
the Htt1ons1 Instituto of Mental 30:1th 1tborttor1es 1n
Lea1ngtan. no othor centcr hm: contributedso extens1vnly to
tn. clinlcul ntud1ol of‘nnrcotic antagonists (an cyclaaoeina
1nd naloxnne), the neurophwa1alosy of anthadone and heroin.
tha eliniaal pharmacology of levcnnthadyl, and avan the
touting a! sane "unsueecaaful" thorupie: as tybalnte.
¢Cu$rophanox1na, and unloxone pgnoste.
‘

It 1: to be rogrcttod that the staff unnuﬂblud and 1r§1ncd
so painfully should b0 dissipated; thnt the offartn on behtlt
of pa11enﬁu :hnu11.bo endnd; and tha research tarn1nated.
Ferhnpm,
lint at thcpgﬁbl1ctt1ans tram this program and 1
far of the rogent reprints any inf1ucnee the ﬂostruntive
eaﬂrio vh1eh the 106.1 uu1haritios at Mbtropolitnn have pursund
no aznunuy (and so tweenmlly) .

t

Sinaaroly yourt.

Fink, M.D.
Professor of Puyeh1ntry
Max

ac. “130: John

87/13

V. Lindsay

�</text>
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                    <text>731-026E

January 15, 1973
Turan

Itil,

Missouri

M.D.

Institute of Psychiatry

shoe Arsenal Street
St. Louis, Missouri

63139

Dear Turen,
We

very much enjoyed your

visit to

our laboratories

these past few days, and wish to thank you for all your assistance in
the critiqic of our ongoing drug research program. Both Don Shapiro
and I appreciate your taking the time from your busy schedule to
review our ongoing research in new drugs and cannabis.

I shall be leaving for
my return.

or write to you on
Again,

my

Amsterdam tomorrow, and

will call

thanka.
Sincerely yours,

Max

Fink,

M.D.

Executive Director

mf/

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                    <text>W

~

NWmn-Wﬂamzwanww

nun-m:

,Miamvmw—ww*w.ww

g».

mmmu—wumvme

~; a

'-&gt;’1!‘A.*

“1 :www- yam—cw,- t‘um

...

nay”;-

Wn -Wg-qmmw,~,

TBSB»0214ME

Jonathan 0. Cole,
Chairmen,

CHE

anusry 13.

M.D.

1973

Resesrch Committee

ﬁetionsl Institute of Mental Health

Roehville, Maryland 20852

Re:Mﬁ

28323-01

Site Visit, 1/12/73

Beer Dr. Cole,
In response to the questions regarding the use of EEG
measures as predictors end criteris for change in the proposed
study, Activated EEG and DPH Response of'thale Delinquents, I
pertieipsted in the site visit on January 12. Prior to the visit,
we had the Opinion of Dr. Joyce Snell to sugplement our questions.

1. The qusntitstive EEG methods for the evslustion or
the slphs~chlorslose response are not yet available; nor ere they
likely to be svsilsble In the forseeshle future, thus slloving the
sdditionsl funds in the second year (pg h) to be deleted.
2. The technique was described, end the evelustion of the
records by members of the clinical steff st the University of Maryland
will provide, using simple deseriptise eriteris. ressonshle estimstes
of the ehsnges induced by the drug. While the test is to be repested.
neither the investigators nor the superintendent know whether the
patients will cooperste. In response to the question of testretest reliebility. Dr. Monroe indiested that these dots are not
“-

available.

('r.-&lt;A

..
mw

r—

w»..—

guy

”wow.

vwwr

m»wm~1W.*"w~»W-‘x

wwrr

.

.v’twcmm’XTKFI’W-

While the test may have some merit, Dr. Monroe did
not make clear whet was the basis {hr the choice of this test, lesving
us with the‘distinet impression that the inclusion.vss in the
nature of s 'fish—ing' expedition.

is much eonfusion seong the psrtieipsnts as to
DPH,
of
the rslstion to blood levels, and the symytoms thst
the dosage
(sad
the
ere
the evslustioo eriteris) of this therspy. In
targets
oontrsst to the specific nature of the EEO test and its evelustion.
the psychistrio—psyehophsrmscologie aspects of the study seeeei so
poorly aoeueentsd. that the recommendation of the site visit teem,
srrived st unsninously, was Dsfbrral, with advice. The advice is
to include some pilot work to define drug dossge, acceptance of
3. There

criteris and ratings; and also, stteepts to test and
repeat testing in s smell group of suhégctgethaetermine if the
'
pstients' cooperation can he assured:

blood sampling,

‘

-mmwa-m~.n,

wvnrrr

Azumww

Sincerely yours,
Me: Fink, M.D.

7—,

'vr".sv

u" :

�</text>
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                    <text>”"n'

"-'

r

7......

'

'

'7

WWW!“

.-

i,

.

.

.

._. "'«x‘ﬁnux~v---\;v-m&lt;qr.r-wm~m.-.....v

.

a—ws-m-wmv—vw

“rvn -_.~,,.

73B~02BE

January 11, 1973
Peter Fell, M.B.B.S.
Head of Medical Affairs
Fisons Limited

Leicestershire
England
Deer

-

mmvvrrvﬂ

mr‘w

w
.

Horn-.4.

_‘

”Va—u.

A-w..,_

,.—qv

”an:

Peter,

the year end sent me to my files
requested. As I re-read it
after a lapse of 16 months, I found that my ideas about many of
the suggestions were still the same. I am not sure whether to be
pleased (assuming that the ideas were good then) or displeased
(that I had learned so little in the time that has gone by),
but it seemed wothhwhile to edit the copy and update it a bit.
Enhlosed is a revised version for your use.
and

v

LE11 66Y

Your kind

I extracted the

letter at

memorandum you

The work with Derek is going well. We have not been
as successful with 01-63 as Turan has been with GB—Qh, but there
seems to be en added effort to set up some additional laboratories and
we are cooperating in this endeavor. I should be in Europe again
soon, and will write to you, should a visit be of some use to you.
my

best to Vi,

and congratulations on your

latest offspring.

mun-a»:

.w-

”via-&gt;11.“

Sincerely yours,

ru

Max

“wnwv-t

'

'

Fink,

M.D.

_

l

y

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                    <text>731—022CT

January

ll,

1973

mm'wr

n‘ﬂwrwwr'wmwmw

'WW

4..

v

w;—

‘."'1wIIv&lt;/"Y'V;w"wr-w‘"r

7-“—

WWW."

"*rr'rw

*7m;W.-'

~wrmvr‘x'lr

Dear Jim,

It is

to be back at work again. I very much appreciate
your optimistic letter, and hope that we can do as well.
good

Enclosed is the Dornbush and Williams report. They have
been writing to each other and shared a number of drafts. This one
is still in need of some assistance, and any suggestions you care
to make will be appreciated.
many

thanks.
Sincerely yours,
Max

Pink,

M.D.

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                    <text>W-“N‘Ih'

.-

.7!‘-=:IJ' ~;'L:"‘

,,,_.

-*

-r

~~~&lt;&gt;

v-

--.,~m:.-.-=u-rv~&lt;

m-z—

—»-V:IOI'1‘IK€'VV'-

.

’vr‘n‘uv

,

'Wevw-'

—-v.r~.

«cw-W2

w-aqm-

-

a." :hm,--rs m,

mqu~ m. 9.. n"

~—,

- 3—,.-

»g——:.

~

-.-

v..'»""1—V?"Y~ 72w“

7383—021A

January 11; 1973
Sanders, Esq.
Contracts Management Branch
Rational Institute of Mental Health
Rockville, Maryland 20852'

Leo

Dear Leo,

_

In discussing the equipment allowances 1n the negotiated
contract for the study of narcotic antagonists at this University,
Dr. Ycllec reviewed his copy of the contract and tcund a possible
basis for the nisucderstanding discussed last week. When you read
the list of approved amounts fer non-personnel costs. I was surprised that the amounts did not match those in my file.
Perhaps the basis for the error lies in the typographical
error-- note that the equipment item is typed.as 2,000, when checking
the sum ($29,892) would indicate an omission or $10,000- which we
believe was approved in the equipment category.

grateful if your records were reviewed and
the error appears in your copies. it it were corrected.
I

would be

Many

if

thanks.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

max

,7"

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TBB-OBBMF

January 10, 1973
Poster Place
32 West 53

New

Street

York City

10019

Gentlemen:
Today, I delivered three posters for 'framing', and I
enclosing our check for $50. as a deposit. I understand that
the framing will be done this month and will cost $30 each, with
a special charge of $3. for one special painting of one frame
(that of the Magritte).
am

"w

when

Please call my office at
the posters are ready.

212—369

7900 x2h5 or 2&amp;6

Thank you.

n

Sincerely yours,

v,,-~

,.,

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r.

-

mum-m

‘Jqﬁmfiii'n'twigs“?

:9"

mwa'r-‘U-

MW"

'W’Sm,yﬁ"'.Lv

V‘l'f’ﬂ"

73SB~017A

January 10, 1973
Maxwell Gordon, Ph.D.

Bristol Laboratories

PO

Box 657

Syracuse,

New

York 13201

Dear Max,

Enclosed are two copies of the report EEG Applications in
Psychopharmaoology, for your consideration for the third volume or
Pryohopharmaaologiaal Agents.

I trust the report meeta the standards and the goals of
the volume, Should there be moditicationa that may improve the
report, I should welcome your suggestions.
that

on

I would appreciate your changing the address of record to

this stationery.
My

best regards.
Sincerely yours,

Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>"W'm-“m‘mrﬁ-"J‘.

WWW-m.

m»

-

,

.7- ‘;':;W'rzﬁ_

'14‘”; ”up .1 W~F¢y

,

.

“7,.

93“.”? yr.—

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1v

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Ma,.w‘.w~ 1‘

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1»

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.7.

r

r'vvv"

...-..~

mg." n

"av-r

.

w" w,

TSSB~015AO

January 9. 1973
Robert C. Tucker, Ph.D.

Drug Dependence Institute
Yale University
98 Park street
Haw Haven, Connecticut 06511
Dear Dr. Tucker,
Thank you for the invitation to participate in the
graduate seminar round table on nev directions in treatment in
New Haven on March 7. 1973. I would be pleased to participate,
and look forward to the opportunity to visit your center.

I have marked my calendar and will anticipate further
details as the final program is prepared.

wv-w'nﬂn‘

‘w

-

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>w.

"*‘qvlwrmw‘nﬁ‘mmrrﬂ-w-‘guowas-w-wawvvm'twmmnw,m&gt;wmm«an vrw-ws:

rune-u- ,

-=

7-29)»:

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. "swam,

3....7.’

-,

var-r ' w- when mr

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2"}:

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.~n_

73 SB-OQO~0

January 8, 1973
"w

“mar?!

WI-rwr

Robert L. DuPont, M.D.
Washington, D.C. 20001

"-

Dear Dr. DuPont,

There has been so much discussion and some controversy

about the safety and efficacy of the acetylmethedols, particularly
levomethedyl, that it seems likely that a discussion of the present
data should be of interest to the participants at the next methadone

conference.

is a summary and a list of participants. Each has
already agreed to participate, should it be possible to include this
Enclosed

subject in the 1973 program.
Good

luck in yout program.
Sincerely yours,

~

vmw

v
w

x&lt;5.r-c

(VI'"-wm'

""‘."1‘

‘vwm;mw'l'

Pink, M.D.
Professor of Psychiatry
Max

--.,v:»-r~—

v

V

r

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                    <text>January 8, 1973
Charlad E. ﬁhllg,“ﬁ.3.

‘

Cooréinato: of ﬁﬁsiduncy Training
Vandcrbilt Unzinraity
Hcpartmant 9f Psychiatry
aashvilln, Ienn9guee 37232
133: 13:. haywood w. Z§1dman
'

Beat

9:. Hana:
Laxly in his school career at mew lurk dadical College. ﬁr.
Zdidman app1£éd far summer work in this division. At that time we
.

,

were invulved with the study of novel narcotic antagcnista and he
carried out chmmicsl assays and alao interviewed patients. Haring
the subsequent years, he volunteered for a number 91 experiments as
a subject, in our ass¢y of nan psychotrapic drugs.

In his relationship: I have always found him to be bright,
cooperativa, enthusiantic, and éepandnble. do worked well with my
Vitaff and with the patiantn. I believe he would make an industrious.
and

cnthuaialtic‘trnince.
&amp;3 hi expressed an interaat 1n

paychOpharmacblogy and because

high opinion of tho program It your Univerﬁity, I
in suggesting that he apply for further study with you.

of

my

was

Sincerelyyyours,
ﬂax Fink, 3.0.
.Profosuor 9f Psychiatry

Ming

instrumental

�</text>
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                    <text>u

.»n-.-:-nnu-W~&lt;.¢u

“mn1'-an&gt;-M-1mzw~warr

x

-va-—r tw’gr.

_—&lt;»

.'~."".!‘ 7 urn-w. '1WV“?"JW"‘¢’q-Nx~ ”w "any-4F“

73SB~01hA
Mr. R.

J.

GradweIl, Contracting Officer

-.—.

”rm”.

rur.‘

WV-.—

.»1-

e

.

.w.v'-"

g

y

.

y

,.

.‘

-

&lt;2&lt;

w

January 6, 1973

Contracts Management Branch
National Institute of Mental Kealth
Rockville, Maryland 20852

.~

“w

run-r,

I an.vriting with regard to the equipment needs of the
contract, Antagonists 3.3 Qgiates (31-6068A) at this University. The
proposal calls for an evaluation of the efficacy of eyelasocine and
methadone in the treatment of opiate dependence. Among the criteria
are those for an adequate dose or methadone (tolerance to high doses),
and e blackening dose of cyclesocine. defined by its blockade of an
administered dose of an opiate, usually diaoetylnorphine (heroin).
The criteria for blockade are subjective reports, chooses in behavior.
respiratory rate, papillary size, and EEG. While no single criterion
is essential, none alone are satisfactory, for expectation and set are
important aepects of an addict's response to an injection.
_

In the negotiations in June, we indicated that some equipment
for the study program would be avialable, including an EEG, but not the
tape recorder necessary to provide the interface between the EEG and
the computer analytic facility at the university. Nor are we able to
provide the equipment for pupillonetry.
Should objective measures for the effects or eyelasoeine be
pupilloneter and a tape recorder should be
provided. Should subJeetive criteria be sufficient for the evaluations,
these requests thould be denied.
deemed important, both a

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

,

3mm

1'qu

n.5-

(wwa-wwgw

W‘Wwvmu‘w'

-

Dear Mr. Gradwell,

cc: Alon Ramsay, M.D.

�</text>
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                    <text>H

menu“,

(\é

7—.

1w.

“mu-(we r‘vvr w".-

q-r-u—v

wv'w‘arv’ug-w»wa;' ,‘ 1F.—.~.-N. -‘..

"aw.—

.,.,

‘WW-m-ll’ 7.53“” w./,..,‘._.y.—..‘.,r&lt;r—.~— her—WW...“ ~;--'-—.-'va- Qwv~4un "In
V

wan-nu-

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-

-

\

7383—01333

January 6, 1973
Janice Stevens,

M.D.

Massachusetts General Hospital
Boston, Massachusetts OEllh
Dear Jan,

It is good to have the opportunity to review an ECT
and one that seems well founded and well designed.
again,
project
months ago, I received the engineers report fer review-by Weaver, Rvaris, Rush and Peananen which described the
parameters of the seizure stimulus in exquisite detail. At that time

the report

Some

I found the report fascinating reading-- a bit too long for the

Journal, and recommended approval with a suggestion that the number of

tables be reduced.

Apparently, these authors have interested a young psychiatrist
in the problem, and the design of the experiment, the selection of
cases, the intent, and the methods are all good. The project needs
doing, for as the recent report and editorial intthe Archives indicated,
the machines we now use are faulty. and the parameters of the stimulus
are poorly defined. Indeed, in the engineers report, they refer to
the best papers in the field, including that done by my associate
(Green, 1960) and Maxwell (1968).

If there are flaws in the application, they are trifling.
for example, is the emphasis on producing a stimulus which
is minimal in intensity (see page 17, last paragraph, "It would seem
almost a prime fhcie case that the use of the least effective energy
dbse would result in less short—range and long-range morbidity."),
when what they really wish to define are the relation between the parameters
of the current and the therapeutic effect (measured as changes in
behavioral scores) and the morbidity (measured as changes in the
Reitan battery). The latter emphasis is more mature and more in keeping
with an academic need and tradition, but the other View is not one
that is easily criticized.
One,

I would also question the sequence of problems they wish to
attack»~ but that too is a matter of style and not a criticism.
application asks for little
principal question of cost is the item of administration of
the Halstead tasks. This is a complex test, and if done by rote, by
a psychologist paid by the session, the results may very velllbe of

extra.

The

They are well equipped, and the

5--

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. .

I, ,7 .

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V

,

,

c

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mu. ~,-‘,‘,w..,..,”manqﬁrﬂe.

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Janice Steven'oaooaso...oooseoeceaa.o

7.,

2

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limited value. Taking measurements in depressed patients before
treatment is difficult; and taking them after treatment may be
confusing. I would hazard a guess that this expenditure will be
wasted. The solution is to recommend the appointment of a psychologist
(even at an increased cost) who could attend to the measurement
of memory test changes. From our work, the memory tests (only some
of which are in the Reitan battery) are the best indices of the
differences betveen unilateral and bilateral seizures, and
between single and multiple seizures. If they follow the usual
'consultation'method, these data will probably be useless.

If

to save money, you could ask whyﬂush is
should have already been given (and
advice
being paid-~ his
Paanenen is not, yet he will build the instruments ).
proposal;

&lt;

W'-

‘

'

'
rw-

~

~

one wanted

of detail and tactics. I like the
field; there is little similar work

But these are matters

it

is

needed in the

going on that I know of; and these non do haves prior experience in
animals upon which they are building. In the site visit, I would
be most interested in whether the P.I.. Dr. Nies, seems capable of
bringing the talents of a psychiatric nature that are sorely needed
in the evaluation to the setting; and also would ask about the

test battery.

mxxr-rr-mvmwm-v—v-wr

thanks for letting me read this prOposal.It is
interesting rollerbup to the report I read earlier by the
engineers in this team !
My

..

My

an

best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max

w»

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.
_
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um.

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.5.

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�</text>
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                    <text>73I—0121

January 5, 1973

“ull”-xa

an

'm'w

«w.

‘r‘l—

,

Greenville Industries Inc.
Bancroft Estate Road

PO

2312

Wilmington, Delaware

19899

Gentlemen:
A

few years ago,

at

in e 10 inch length, in

my

former

institution,

we

purchased

which have been most useful. These came
two 'widths', and many colors.

plastic binders for reports,

If you still manufacture these, would you please send me
a page from your catalog with the prices and ordering information, for
the narrow (?k inch) and wide (78 inch) widths.
Thank you.

Sincerely yours,

Max

Fink,

M.D.

Executive Director

�</text>
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                    <text>._,..,

w-.."

.1,Vg.._.r—.—wvm

:gvv -,—nm a

9. q

—

‘

‘pm ”‘7 ..

1

"g.,w'rmva,‘Wu.-W~‘w-»«'Ww‘m""

,.

.v

’-r~w’='

,

.-

:‘r-‘vra‘lwws

.7:

-

rwv- 'ir " "t"

731—011-JV

January 5. 1973
Aﬂvanced Products
Hewlett Packard Corp
10900 Wolfe Road

Caper-tine, California

95011;

Gentlemen:

the

list

He

would

price of

like to order

3395.

one

HP-BS

Please ship to:

Fink. M.D.
IAPR, Inc.
PO Box 269

pocket calculator at

Max

Great Neck, R.Y.

This Association

is tax

11022

exempt and the appropriate

submitted with this order.

TE

forms are

Sincerely yours,

Max

Fink,

M.D.

Executive Director

�</text>
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                  <elementText elementTextId="106632">
                    <text>n-u-w—a. ..

t

v

wy-w-mvunwwz—m—nwmw

A

,

..-,...V—

r.

_

.

_

,

_

wwwgmwx—M

V‘m’vwmmmwmwvﬂﬂ'u“yr.

‘34,." .-

nu.

u—Wnr—zwvy m

. L~1Wm~~--~q.vux\a'" -

N73—009AP

Alfred Freedman,

.

4“,..wmﬂvrﬂu'ln‘wu'1‘y-

.ml,

.

New
New

M.D.

York Medical College
York City

Dear Al,

E.

o

I

have reviewed the records of the
suggestions for 1973-7h come to mind:

,
"'7.”

on

gum-k

A_

APPA

and

the rolloving

President Elect: Ch. Shngnna
Vice-President : A. Priodhoff
:
J.O. Cole
Secretary
:
DJ‘. Klein
Treasurer
Councillors

:

Gerald Klerman,

M.D.

rv-rrm

gm.-

Both Friedhoff and Klermnn have served the Association well. Should
you wish to consider other: who have served the Association, both
Ron Ficve and 8y Fisher should be considered. As an alternate,
chrman could be asked to serve as treasurer IDr 1-2 years, and Klein

could be considered for Councillor.

is one other maneuver: increase the number
by rc~nominating Fisher and adding Fievc.

There

councillors
I

hope

these

comments

of

are helpful.
Sincerely.

'"WTWWw,

5"

'
mm

n

i
-‘

mm‘rv

mwm'wu-wrvﬂ'w

Max

Fink,

M.D.

�</text>
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                    <text>-~-vVI'”FA.-7'I(4—

,,. ..~—..\....g..

,

r'wvuw- "W“;

gm.

.—..—~..r; ,‘mw—

z-Wm—q-q—‘vw-“aw—Amean». gawk-m.» .m .~-.—’V"r

..

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:,

...

in,”

N 73 oafﬂ/

73N-od8m

‘

January 5. 1973
Mr.

Arthur J.

Lunny

Grace Instrument Co.

Quincy, Massachusetts 02169
Dear Mr. Lunny,
Thank you for clarifying the remaining order for EEG chart
which
I have with Grace Instrument Co. In the ensuing weeks,
paper
my staff will call and ask that the remaining boxes be shipped to
one of my two laboratories, at the New York Medical College, or

Building Surge

I,

Room

2310, Health Sheencee Center,

Brook, Stony Brook. ﬂew York 11790.

that are
result of our split shipping.
charges end service charges

H

g
5

,

We

SUHY

at

Stony

will defray all shipping

due or may become due no a

With regard to purchase order

516318 dated 11/29/72,

I have asked the purchasing department to cancel the item #2,
"50 packs EEG paper. 10", at 3.75, $187.50"; but to retain the
other 3 items, for electrode cream, pens, and IF 100. If not yet
shipped, I vould appreciate your sending these items to my attention
at:
Department of Psychiatry

5 East 102 Street
New York City 10029

I em most grateful for your cooperation, end wish
your associates the beat of health and success in 1973 l

you and

Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max

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                    <text>run-v

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I73 007I
73I—OOTI

January
Jersey Tab

5 e 3-973

Co.

6&amp;9 Runway Ave

Union, new Jersey 07083
Gentlemen:

to

my

Enclosed please find payment for e shipment of cards sent
attention at BURY at Stony Brook. Note, for your records.

that the purchasing organization is cited on this stationery, and
the organization is tax exempy. The appropriate certificates are
submitted for your

files.

'

Please honor future orders submitted by my stuff in my name,
shipping to the address at Stony Brook, end bill to this organization.
.

’

Thank you.

Sincerely yours,
Max

Fink.

M.D.

Executive Director

-~-.

wv—uw

�</text>
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                    <text>STATE UNIVERSITY OF NEW YORK AT STONY BROOK

HEALTH SCIENCES CENTER
School of Medicine
Stony Brook. N. Y. 11790
Phone: 5164444413

Department of Psychiatry

January h, 1973
TO:

Dr. Morton

FROM:

Dr. Max Fink

SUBJECT:

Psychiatry Electives, 2nd Year Students

G.

Miller

//

I have read the five proposals, and
cannot attend the January 5th meeting.

am

writing because I

For students to do an overseas elective without local
experience is like serving champagne without the dinner. But
if such electives are fostered, I would rank the requests,
for justification and enthusiasm as:

l. Geisinger

MF:ml

- suggest at C.I.

2.

Garber

-

ok

3.

‘Webb

-

seems

h.

Seltzer

- supervisor?

5.

Murray

—

first

for Israel (Supervisor?)
best for England
seems too vague

should do work in

New

York

in Guadalahara

first

�</text>
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                    <text>J

.1
m

"my-u-

vv-wwwm-

w"

'W-'.1u':wr1;wvrv-

”.rr

N”

7.

‘vamw-

m-

mummy

“NV -_ “W7

H,

mm

7388—006Sc

January 3, 1973
Mr. Herman Heisman
Hofmsnn—Ls Roche
Rutlcy, Rev Jersey

Dear Hank,

I very much enjoyed my visit to Nutley and I hope the
discussions were as profitable for you as interesting for me. I
will collect some samples from the next subject or two at 9 and
mg bromsacpsn, and call you when those are available.

12

Perhaps you would do as s favor. I found the discussions
interesting but at this momsnt have difficulty in noting the
names and identification or the many newborn of the staff that
I met. Could you send me s 'scorencsrd' 1
Many

thanks.
Sincerely yours,
,8)

rink,
m
Professor

McD-

of Psychiatry

�</text>
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                    <text>T3SB-005NY

January 2, 1973
Charles E. Wells, M.D.

Vanderbilt University
Department of Psychiatry
Nashville, Tennesee 37232

Re: Heywood E. Zeidman

Dear Dr. Wells,

Early in his school career at the New York Medical College,
applied for summer work in the Division of Biologﬁcal
Psychiatry at the College. At that time we were involved with the
study of novel narcotic antagonists and he carried out chemical assays
and also interviewed patients. During the subsequent years of his
training, he volunteered for experiments as a subject.

Mr. Zeidman

In these relationships, I have found him.bright,
cooperative, enthusiastic and dependable. He worked well with my
staff and with the patients. I believe he would make an industrious

and

enthusiastic trainee.

expressed an interest in psychopharmacology, and because
of my high opinion of the program at your University, I was instrumental
in suggesting that he apply for further study with you.
As he

‘1

.WI’V”

Sincerely yours,
.

'

1/
‘,-

x)

1:-

W'Igcmrwu'"

m"

marmwr

Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>“mailman

run-1

.

(01‘!

3.,

up.“

73;%}¢9o/ 50’

zmzﬁmrz".mv"“r&gt;"w

January 2, 1973

wvm&lt;m"’-vrm"

mr’q‘wum'xr

Martin Katz, PH.D.
Clinical Research Branch
National Institute of Mental Health

Fishers Lane
Rockville, Maryland
5600

'I"‘M}WW.WI

x

Dear Martin,

~

rump—ruin.

.,

a
a
5
mm)!

swmwm

T"
.
~v

row

&lt;

awn,"

Anticipating the needs of the APPA for 1974, I recalled
discussion
in San Juan with some special interest. If I understood
our
the thrust of your remarks, the Association might attend to the new
methods of studying psychopathology, both for the insights they may
elicit, as for the research models and methods they represent.
Cross-cultural studies, family and sibling studies, treatment
response for diagnostic classification, genetic typing are some
approaches that were mentioned.

V‘Wﬁ,wr‘7

some

'WWH'W’HW'

‘W'mrIK-‘smv

JW"

'

interested in such a program, and would like to provide
basis for discussion at the Council meeting at the end of
I

am

February.

I would be grateful if you would put your suggestions down,
perhaps including some nominees for participation. The meeting will
be held in Boston, and we may wishto take advantage of the intellectual

diversity of

my

its scientists.

best wishes for a healthy

and happy 1973

!

Sincerely yours,
u

var?

imww’w

var"

&lt;

-'

MW

'

“mu-pmr'cx-xw

«
&gt;

v"

«r-nr‘

’1‘"

Fink, M.D.
Professor of Psychiatry

Max

'

�</text>
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                    <text>“PWW‘F,” 1

.7

Tut—m;,was.W—r‘

rpm

mu ,
.
:u‘wfw'mu

: as

l

.

.

,1:

m

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Wuhan-~11

731:00hI

January 2, 1973
M8.

C.J. Varin

Abbott Labels Unlimited
79

Mill

Road

Freeport, L.I.

New

York

Dear Ms. Varin,

I have received your brochure and samples and wish to
ask your bid on the following perma-stik labels, to be used to mark
equipment for identification. The labels can be in silver, or if
color is no additional charge, in blue.

size of the

The

sample submitted

is satisfactory.

request sequential numbering in the following series:

We

72-100 to 72-299
73-300
7h-hoo

to
to

75-500 to

The

73-399
7h-h99
75-599

text to read:
##-###

Inc.
P.0. 269

IAPR,

Great Neck, N.Y.

delivery.

I

would appreciate a

bid price

and approximate time

for

Thank you.

Sincerely yours,
Mex

Fink,

M.D.

Executive Director

P.S.

If there

are questions, please call at

Sl6—hhh 2hh7.

.z—Lr—g._q_._,_..

Mr “ﬁg—"wwvrmn.

�</text>
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“In...“ .

731:003CT

January 1. 1973
James HcGaugh, Ph.D.

Profeeeor of Psychobiology
University of California

Irvine, California

92666

Dear Jim,

sent the enclosed contract for the publication
royalties, I opted for the lower
market price for the volume, allowing for some return for the editors
by using grant funda for editing. The Association can make $1,500
available for editing, thereby aubventing the voluae'o coat to the reader.
of the

Mr. Erlbaum

ECT

volume. In diacueaing

The

contract includes our connittuent to deliver the manuscripts

by the end of February, with the volume to be issued in September. Mr.
Erlbauu sent me a sample cepy of a book ieaued by his group and
compares favorably with recent psychiatric volumes. Furthermore, the volume
will require no typing by my staff, for the text will he not by linotype.

it

If the contract in satisfactory, please sign and return to me.
As to what has to be done this month. there are three things

that are required:
soon as

1. Your report to the Conference should be submitted as
practicable, but no later than nid~February.

2. Your review and editing of the reports sent to you, for
such comments as you may wish to make, particularly to avoid inconsiat~

encies in the volume.

3. An overall summary of the meeting wee part of our committment
Such a summary was requested for the use of the various NINE
committees and for publication. It is my understanding that Dan Fteedman
has agreed to review these summaries for the Archives of’GoneraZ Paychiatry.
Although we have agreed to publish the summaries separately,
may be
advisable to include them in the volume as well. I believe this would
be most useful, and while
will require special permission from both
Mr. Erlbaum and from Dan Freedman (should he accept), I would like your
permission to make such an effort.

to

NIHH.

it

it

Despite our individual busy schedules, I hope we can make these
committnente -~ the report for the volume, the edited manuscripts. and
the summaries, all by the end of January. My best wishes for a healthy

and happy 1973

I

Sincerely yours,
Max

Fink, M.D.

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                    <text>731:00202'

Januart

1, 1973

Seymour S. Kety, M.D.

Professor of Psychiatry

Harvard Medical School
Boston, Massachusetts 02114
Dear Seymour,

sent the enclosed contract for the publication
volum.
In
discussing
royalties, I opted for a lower market
of
volume,
the
allowing
for some return for the editors by using
price for
The
Association
can make $1, 500 available for
funds
editing.
for
grant
volume
'8
the
cost to the reader.
subventing
thereby
editing,
the

Mr. Erlbaum has

ECT

The

contract includes our comrittmsnt to deliver the muscripts

by the end of February, with the volume to be issued in September. Mr.
comErlbaum sent me a sample copy of a book issued by his group and
volume
the
volumes.
Fwﬂzermre,
with
recent
psychiatric
pares favorably
will require no typing by my staff, for the text will be set by linotyps.

it

If the contract is
that will

As

be

to

satisfactory, please sign and return to

me.

what has to be done this month, there are three things

required:

report to the conference should be submitted as soon
but
no later than mid—February.
as practicable,
2. Your review or editing of the reports sent to you, for such
comments as you may wish to make, particularly to avoid internal incon—
1. your

sistencies.

'

overall sumry of the meeting was part of our
£11743.
Such a sumsary was requested for the use of the
to
comitmnt
various NIMH cosmittees and for publication. It is my understanding
that Dan Freedman has agreed to review these swmardes for the Archives
to publish the summaries
of General Psychiatry. Although we have agreed
them
in the volume as well.
include
be
advisable
to
may
separately, it
and while
will
be
the
volume,
would
in
most
believe
useful
this
I
Dan
Freedman
Erlbaum
and
Mr.
with
with
both
require special negotiation
(should he accept), I would like your agreement to make such an effort.
3. An

it

Despite our individual busy schedules, I hope we can make these
commitments «- the report for the volume, the edited manuscripts, and
the sunnaries, all by the end of January. My best wishes for a healthy
and happy 1973 I

Sincerely yours,
Max

Fink,

M. D.

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                    <text>7383-658

April 30. 1973

:v—vz-v

“gram-v

.

3.8.

Dawnrtasnx of

P.0.

Box 28083,

Bureau

Justice.

at narcotics

and Dnngcroun Drugs.

Central Btdiion.
Hinhington, D.C. 20005.
Gentlunnn.
Enclosed is an tpglieution for rogistruiion uﬂﬁer
uontrollud substance: act a! 1970 an cayertcr.
ﬂinae 1970 I have been project director or KIME
damn-net I38! hears-98, study of Rankin}: Ham in Grace.
During this timn wn have brought into thn United States
aanplau of hashiuh for assay (DEED P?0080527).
hsvu ulna been shipping supplies of marijuana
obtained from the HIKE to the University of
Axhcnn undnr thc study program. A shipment sent in
Deecﬂber has boon held in dugtaus in Athann. The
university of Athena has obtained a legal impart permit.
They have requested that 1% obtnin an export license,
und sitar some enquiry, I find that an arc to apply
dh nova. Enclouod is a request for ragiatratien as an
exporter. Since 1% in irrelevant to an whether this
licenae be issund to my ofriee tt 5 East 102nd Street.
9r at Stony Brook, I an bringing to ynur nttention that
I already hold In import license at 5 Butt 102nd Strect.
I! it is gullible to it'd. an export lictnse tram that
site pinata do so. If it in not. enclosed in an
and

Vb

THC

application fur registration tram this site.
Fbr your infornntion, VI hare been

fully inspected

tn; stste of New York at this location, and the
invactigtting ottiacr. Mr. John Cotsolinn, has assured us
thnﬁ Vi mach thy rogulntioaa of the stain far the management
or eautrollad subatnnces. I would b. grataful for any
dilintancc in this muttqr.

by

Sincerely yours.
w‘

.

Fink, M.D.
?rofcnsor of Psychiatry
Mb:

ml 1.1
Ens.

�</text>
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                    <text>‘
,4
A

am

um

w“

“-2.47

‘lwv‘lrv’wvmwvmv‘n-vrvvr'l'!

7383-637

April 30’ 1973
IBM

Corporation,

Program Informatian Da’%..
h6 Industrial Ave..

Mhhwnh,

H.J. 07h30.

Re: 6&amp;16208~§§§gh233;;

Gentlemen,
The IBM 1800, which gravioualy was at 5 East 102nd
New York City, is now located at The ﬁtata
Uhivarsity of Saw York at Stony Brook. we would

Street in

apprecia$e receiving further intbrmation about tha
that your rccords be

prograna tn: the 1800, and ask
changad to:

H3: Fink. Mano

Health sciencal Genﬁer,

Departmant or Plyahiatry.

The

State university of

at steny Brook,

8“” Wk. 3.3.

Haw

York

117909

Sincerely yours.

Hi: Pink. K.D.
Profs-so: of Psychiatry
Mllid

Eta.

�</text>
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                    <text>7M6”
Dr. E. 3. Terry.

Nadia-.1

Dinner

911m. Rum]: (Guam) Ltd”
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W: Blvd. ,

wink-.0131”,

mutt.“

73°.

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um. «king 1! we would1nbe tutu-outed in undertaking
«tutu-s of mpmlol
opiate addicticn. Enclosed
this woman. It in
an three men rolmnt to
that snow bu decided to take aux-tonal:
”punt
the work of Dr. Kama ﬁrst: or Indimpolia. My own
or Dr. Grou’
in that it doe: not Justify
“that.
extensive work at this time. I believe that he should
be same“ to do some “tench. audits to Justify
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anemia afﬂmy.

I trust thia is of tone tutu-Mt.
Binamly yam-I ,
Fink. Md).
m
Professor of thutry
30/13

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April 3°, 1973
Maven

Elm.

H.123...

Heme]. amen,
mum
5600 Fishers Lane.
mmue. Minna 20852.

Beer

Inititute or

8%,!

m

I vould appreciate
help in getting ewe
ta Dr. steam: in Athens. In his latent
letter he elk: for en “Maul 500 we of 2.5}
momma-9 «121mm.

mum

In December, renewing mar usual custom. we
chipped «stigma. and was at his request. Although
he be: e valid import pet-lit, he in mble to get the
Muriel releued free Greek Guam because we have
not submitted a valid export Home. Since January
and have not been
I have written numerous times to

m.

eble to obtain an export license. The material in
still impounded,- md time we are nations that he
emanate with hie 9M1», Misuse-1y u pert of the
withdraw-.1 study it I. an
to determine 1:
can
substitute
for
I vmzld
mean,
serum
from this
in
uterine).
the
help
your
setting
emanate
address
to
in:
his.
an
«entry

new

”up.
W13.
a!
Dome thietry‘
CCU“.

He

(Inﬁnity Medical school.
Hospital,
Vuiliuie Sophie: Av. .

Athena

35111114101:

Th.

“hm.
I

Greece.

enclosing an amen]. order form for 500 area.
(or wrong”). 81:91:14! 1% be feasible, I
2M
mama.
am

�8W Sm. IN).
would

on

-2.

April 30, 1973

that this be «mm directly to Dr.
2%“
or 0th.! malt-bl. export Home.

m

31mm:

W thanks.
81mm]; you”,

it: Fink. 24.13.
manor of Psychiatry
10/13

M.

�</text>
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Tam-655

April 30. 1973

gyv—gmzmr

.

.

1,

-

‘5‘mn’a7'w7—vy-Juew4’:

,

Ms. Linda

Stein.

Membership secretary.
250 West 57 Straw. Room 1201,
1!“ York, NJ. 10019‘

It is difficult for we to decide on whether my
activities in the rmmmm your: V111 be in Suffolk

a

county, where I haw
office. a: in Hanan County,
I have my ham. I m not enthusiastic about
making that choice at 131“ mount um, and ﬁhoreforo

where

this ”quest for tmafer of membership
snub a use an I «a
Until
magma.
that
decision, I with to resign from the Rev York County
District Branch, without specifyim Mattie Branch
an returning

m

Membership.

Binenraly your: ,

Fm. “CD.
m
Professor of

thu‘bry

lit/13

Em .

�</text>
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                    <text>w-p‘

v-..

7388-653

Ayrtl 30, 1973

Joya: Lavinson,

M.D.,

Rational Assoc. far the ?ravantion of
Addietion ta Ehreotiaa.
175

Fifth Awu..

new York. N.Y. 10010.

Dcur Joyce,

Fallawing our letters of curly March, I hnve not
heard fron.you regarding the wanting: in Yugoslavia.
There 13 a possibility that I
during that ﬁlms. If it is at some

will be in Europe

interest. I

would

uppreciata any inrbruatian regarding the meeting which
you may hnve awnildble.
my

best rognrds,
Sincerely yours.

Nb: Fink, M;D.

Profonlor or Payehigtry

MFIIJ

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April 30, 1973
n

..

v

,

.A.-,

‘1’

l'vpv-Ir

wJVy-nz-I—J'n‘

Gerald L. Kliiﬁhn, M.D..
Professor of Psyuhiatry,
Harvard Mbdical School.

Musstchuaettn General Hbspital,
Boston, ﬁnes. 0211h.
Dear Gerry,

I

grataful that you urn willing to mar?! an
of the Myabaruhip Oommittea fbr the AP?A.
I discussad with Jon tha addition ta the Maﬁbership

Chnirman

am

Committee of members from Boston and washington, and
ha agreed to ask yuur advice the next ttme he chatted
with you.

ﬁbula you poll the Madbarahip Cummittee sud be
prepared at the Council maetins to make a fbrusl
suggestion regarding an increase in maﬁberahtp, both
in number and in elasnitieution! (Perhaps one way of
gutting sround the foclins or elitism in to create tun
cllﬂl0l of numbers. such an tha ACHP did. I am not
reeounnndtns this, but suggesting it an a nutter fbr

discussion.)

I lack forward to neatng yen at the

and

of

Mhy.

Eincerely yours.

Mn:

rink, m.n.

Prafclsor of Psychiatry
MF/ij

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                    <text>7383—613

April 9th, 1973
W-

~

-

u¢rwm~r—.-.

my.“

Gerald L. Elurmen, M.D.,

Hhssaehnsetta General Hospital.

Boston, Hess. 0211h.
Deer Gerry,

Fbllawing our discussion in Kev Orleans, I
reached Jon two days after he bed seut out the list
of invitations fur the Heatership Committee. He
van therefore unable to make the corrections that you
suggested.

I think it would be epproyriete for you to
frame a series of recommendations regarding an
increase in membership in the APPA. and the constitutional
changes that would be necessary to accomplish this
mission. These should be presented at the next meeting
at Council, and the group's opinion determined. I
believe yen will get a favorable response.
As for the Arrangements Committee, Jon suggested
Jim Barrett , me you suggested c. Pierce. mania}; mm
Jon should invite either or bath to work 171th yen.

wheat you for your kind thoughts. Much of the
motivation for expeneion of participation by the members
in the APPA cane tram cur discussions and your letters.
I an. as always, grateful fur yuur advice.

Bineerely yours.

Mb: Fink. M.D.
Professor of Peynhietry
rum/1.1

�</text>
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                    <text>mTJﬂVW

wan;

J:wm&amp;m

7383-582
Miran 213%, 1973

Gerald Klermnn. M.D.,

Profaauor or Paychiutry,
Harvard Mbdiaal School.
Erich Lindemsnn ﬁhntal Health Ccntar
ﬂovarnnunt Center.
Bosﬁon, ”has. 0211h.
Dear Gerry,

Follawing are coma comments on tbs ACﬂF task force notes of
6th deruary. 1973 regarding both the ganoral connidcrations and
tbs proposal for evaluating antideyrcnsnnt drugs. my comment:
may also be relevant to the notes by Uhlcnhuth and Wittenborn.

l

D

While

etio of base of at
the general utnxamnnts

alicit

criticism. I am confused by the mission.
safety are different tram guidelines fbr
necessary differences in rules :0: phase
by «aperioncad clinicians from rulaa for

approval and little
Guidelines for testing

efficacy. There are
I and donatinding studicl

phase III general clinical
surveys by an army of technicians. and phase IV clinical trials by

hosts of practitioners.

I read the guncrnl eonsidnrations, these seem recanted on
utudics - varifieatien a! efficacy in small tangles
II»!!!
phll.
A:

by techniainns. What or tbs apoainl issues of
(9.)

identifying clinical populations (phase I)

(b) doslgc usasuruuent

(a) plmiologiou affects including toxicity?
In the guidelinoa. the seloetion of degraaaod patients is
sacred no a lymgtau, cauglcx. and a diseasa. and rouolvuu tbs
dilamms by approving all ﬁbula. I belicve these distinction. to
be inpartanm,and while thn identification of homogeneous yopulaiiona
for phnso III-IV studio: in a difficult chore, it is any that neeaa
eumhnsia. Thane diltinetions are Ivan were important in phage I
trials. where hnt¢ro§enaona populations should be encouraged, and
thc data presented not as atumiaticul "salamia" but an eaaa roeords.

t

�‘Dr.

Gerald Klernen

~2~

Mirth

alet.

1973

interrelation of eymptem, syndrome, or disease end
intervention. (The eeee‘studiee by Klein make e unique contribution
in this regard, and eupport for such studies is warranted). Again,
the distinction of goele of eeeh study dictates distinction es to
methods, and I suggest that the guidelines than: on different
”phases" with different guidelines. (Fer another opinion, see
focueaed en the

Ballister Iencloeed)).
23

Digtineticn of dogaae

Differences in dbeervetiene. particularly as to efficacy.
are related not only to the tergut symptom and population seleeted,
but delivery of adequate doses of the agent to target urgent.
Repcrts of wide differeneee in blood levels with thymoleptiel and
lithium, when patients ere given the same dosages, has led to
Ipeeuletion (bout genetic differences in metabolite effecting
therepeutie results. While genetic and metabolic differences may
indeed operete, the inteke, ebeorption, and the influenee of feeding
éoeege ere eimpler. more mechanical issues that reqtire study. As
with the utility of blood lithium, and blood DPH levels, perhaps
the recommendations should include comments that where physiologic
indieee exist, therapeutic studies should include concurrent
dosage—index measures: at e minimum, daily (or more frequent) urine
end'blood levels; and, so frequent heart rate. EKG, or cerebral
bioelnetric measures where these may reflect tissue levels. Cerebral
bioeleetrie measures, reflecting the effect or an agent on e target
argue most directly in antidepressant therapy, are the best index
of changes in cerebral aetivity, end here wider a plieatione than
the guidelines reflect. (Cerebral potential [EEG studies also ellov
en identification and classification of antidepressant, thymoleptie,
end euphorient drugs, peovidins a guideline as to the related

_

comparison treatment).
31_Heeeg;ee of
To

some eecegtenee of e new antidepressant, only
some cardiotemicity or to effect the lens of the

gain

it to have
wuuld

toxigity
to find

eye,
serve eoeiety little. I have been coneerned by the neglect
er eerdiec toxicity in early eveluetiens. for example, with
thioridesine and meeoridesiae. An evaluation that does not coetraet
e profit-east eeeounting is e poor evaluation: to estimate effieeey
is limited if it does not eentrest with the esteblished, "effective“
standard. Thus. the guidelines may suggest that change scores of
behaviortl measures ehauld be evelueted in the same net as ehensee
in blood. cardiac, cerebral, ete. memes. (m. after item: 1 and 2
[page h], there should be en eeseeeuent of "neeendary" effects).

(In this regard. item: h, 5, 6, 7 ere clearly poet~eveluetion
indiees, useful to the technicians and elinical researchers, but net
relevent to evaluation in pheneIIIIII efficacy and safety).

-

�“It:

wanna

—

1mw—

r,..,w.°4-1,‘

'

wm‘7e&lt;»-.‘

varnn—s

‘E‘F'V-W

Dr. Gerald

new

~3—

march

21».

1973

There is a particular prdblan in assessing antidepreeaants:
the ”standard" is not well aeeepted. fer imiyremine and amitriptyline,
MAO. and EGT are each queted by different evaluator! far different
purposes. Fbr a "unJor" antidepressant. it may have he be contrasted
with ECT. Fer the othere,'with imipramine. The guidelines might
auggeet when to use which contrast. and perhaye discard any continued
use of MAO inhibitors aa a standard.
The eeparation

of phaae of atuiy and heterogeneous, case studies

fer phase 13 emphasis on homogeneous population: fur phase II, III;
distinctions of dosage and physiologic indieee; and eoetuprofit
analyses fer toxic ayumtome are questions that are alto lacking in
the antiwanxiety guidelines. ﬁne notes by Vitteﬁborn reflect an
interest in a very late phase of clinical testing. and.yet he attempts
to approach the relevant inauea. .Aa I read his eaten. hie emphasis
is on phase III, large aeele testing ~ he netee the frequent
diffieulty in dosage. washout, etc. that are also relevant to the
issue a! antidayreaeente.

Perhaps the guidelines are only focuaeed on phase III~IV testing
these notee are inappropriate. Perhape
phase I trials require different guidelines, and such a separation
an Wittenborn suggests; then

be useful in separating and clarifying the guidelines.
er the Cenmittee vieh an elaboration of these thoughts.
I will try to amplify than with more specific suggestions.

of goal

may

Sheuld you

aincerely yours.

w&lt;.z-¢nuv.v.-ur~vrr

r-uv

‘1’\“-r_""l7

ﬁnk . Md).
N
Protester of Psychiatry

"var-qr.

MF/iJ
3Q. To B. WittOnbOm. Ph.D.

�</text>
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                    <text>Downbeat-221m, 1972
Dr. Btruld

chrnan.
Prettisor or Pnyeh111ry

ﬁ:rvnrd utdaonl ﬂannel.

ﬂnuu¢¢huaoﬁtn ﬂannr&amp;l Eosp1tgl,

30‘th .

m. i

own I

Dour‘aorxy,»

_

.‘I an 9101306 to accond 1h. non1ngtion of Dr,
nthXbors tbr*IIIbnruhip 1n the APRA. '-

I

bit: for wort thﬁn A decade, and
rbllavca his rcaaareh efforts in pnrnhothnruny.
and LED v1th arugt 1ntcrcut. For 1 auﬁbor of yoars
he crou$od paaiant: in ca expor1nmntal frcnn 51v1ns
than ctpsulca containing 18». nuphotu-incl. or pluocbo.
Eh. study v1. conglax. bat he carrted it out wall.
ham.

h1vn known

‘

.

K. 1: n town 1nvwnt£gutor and hns Hunk intcrcct
1n‘al1nionl uad cap¢r1nnnttl tupoat: of pnynhiutry.
I in plensod ta roeunuand him tor nunberrh1p.
‘

'

‘

sincerely ynﬁrn.

uh: Fink.

N.D.

Professor of Payehintry

was

an. to Dr. qucph 31!:new

tart $1.1: Puyuh1ntqli-Instituto

�</text>
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                    <text>7%3—612

April 9th. 1973
351mm:

8. Kline. Mm...

Boseurah ﬂenter,
Ruckland State Hospital.
Orangdburg. N.Y. 10962.

Dear Hate,

is ccnvenient.

I
I m guest of the Jansen
family. I found their hospitality macadamia. and.
the occasion is mmble.
I look forward to Joining the comittee 1n

was

Augmt 29th in Beer“

last in

Baez-so,

Became on August

29th.

a.

When

-

Sincerely yours .

m Fink.
Proteuor of Psychiatry
24.13.

EN13

v

HAI‘WKW‘WJB

”/5;

n

�</text>
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gut

wrizgtm"

We

GIVWVK'M“

T"

an

TBSB—SSS

March

5th,

1973

Nathan 8. Elias, M.D.,
Renoarch Canter.
Roeklsnd State Hospital,
Granadburg. R.Y.
Dear Kata.

I would 11k. to he in Mirueillel an the cvuning

of August Slat. I could be in svitscrlnnd
the yrscoding two or three dtya with easy.

on

;ny of

Congr:tu1ctions on you» anniversary celebration.
W

hm 2‘08““.
Sincerely yearn,

Fink, M;n.
Profbssar of Psychigtry
Mn:

MP/iJ

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February 16th, 1973

Kathan S. Kline. M.D..
Research Canter,
Roeklnnd state ﬁcnpital,
OrQngcburg, H.Y.

Boar Hate,
You 3:: asking ‘ difficult qnettion when.you enquire
my schedule this aunmar. ﬁlth some luck I will be
to
as
in ﬁning in August. but should lean. fbr Europe in zinc
to be in Hurseillan septanbcr 1»?.
I will prdbably'be in Europe also during the month
of June. pmobdbly lata; and a third trig will be late in
Getober as I mutt be in Amaterdnm on.0ctoher 27th.

Sinoorely yours,

Fink. M.D.
Profcsaor of Psychiatry
Mix

MF/iJ

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                    <text>7383—515

February 6th, 1973

mew 8.

K111». $1.1)...

numb (hater;
Becpital,
Roam 8?.th
LY.
Gaucher-s,

M an,
your

been 20 no”? I commute you an
rally
to
“19¢qu growthYour
w any unique contributions
been

Ru

1!:

m.

contributions
a credit
ﬁnd
forward
look
I
state.
to our
.
to the unnamed Mmtiﬂw from your hbmtoria.

pmhwmmaloy.
ﬁnd
1m: York

to

Although

I cannot Join
in Gamma.
Ky

boat

I

mum“

would vary much wish

m.

as

'13th

I

for

have
u.

mud

to do w. I ram-vet
to ski with my family

wanna mung.
Simucly yours.
Fink.
m
Professor at Psychiatry
11.13.

149/15

�</text>
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                    <text>vw'r»9-I‘IV‘W",7

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7383~6h8

Ayril 27. 1973
urn. Carol Levin.

President,

Matrapolitcn EEG Society,
Méd1¢al Science Building.

550 First £39..
new York City, E.Y.

Duar'uhw. Levin,

the

Enclosed

"Handboak

is u check for $5.00 for a copy of
EEG"

of

Thank you

of the Society.

for

prepared by

making

Beckmnn

Instrumnnta.

this available to

members

Sincerely yours,

"on.
m
m.
aillusnor of Plyehiatry

ﬁllid
Ena.

..

V

.47...,..

.

.

�</text>
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                    <text>7383~6hh

April 27. 1973
Cruig H. Procario.

"www.mw—y—

Public Defendnr Proaoet,
333 What

A.

First Street.

Dayton. Ohio E5303.

W"'.)‘

5““,

Dear Mr. Procario.

I read yam: letter of April 11th,w1th interest.
rbr s morn datinitivn ropiy than the tailoring, I have
sent your letter on to my autocista, Dr. Rhea Dornbuah.
And I trust thaz she will answer in seat detail.

F

I belicva you nru corrcet in your anaeslnent of
the reports that lav $0.93 of unrijunnn do not result
in hallueinntions ind illusions. Indeed. even it high

it

have
doses, sunk phonauons art turn. In our work
given acne: of marijuann aontainina 10»20 tins. the
euctanary amount or rcactivv prineipnl ‘nd have not

elicited hallucinatory or illnsary royorta.

sincercly yuurn.

ﬁt: rink.

M.D.

Professor of Pcyehintry

Hrlij
cc. to Dr.

Khan norahuah

�</text>
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                    <text>73SBw6h983

April 27. 1973

m:

”Orton 9.

F203:

Max

SUBJECT:

Psychopharmacology

Fink,

Mill”.

Md).

M.D.

Fbllowing your request of April 18th. I upoko
with Dr.
dar Klaat, and VII untoninhad to find
thsk while the studnutn have had introductory pharmacology
(15 lectures), they have had limited exparience vith
drugs affecting the autaaamic nervous syntem. but g3.

th

exposure to ysychopharmacology. Should it be the policy
of the department to provide a background in basic
psychopharmncology? This is a very larga subject,
encompassing, at a minimum, the following topics:
1. Mbdo of action of OHS drugs;
2. Blood#bra1n

barrier

and

its effects;

3. Cerdbrnl neurohmuara. theories of mode

of uction;

h. Neuraphyulologicnl hypotheses, drug

effects;

5. sedatives und hyyuotien;
6. Analgesics, narcotics and
T. Psychotrbp1cu

anxiolytics;

their untagonlats;

(antlplyehntic drugs) and

8. atiuuluntn, nuttdaprenlgnts and thyaolupeiau;
9. Hallueinoganu and dolirisntn;
10. Alcohol, catttino, thaobroulnc.

ctc.;

�\/
Mbrton G.

Miller,

K.D.

~2~

April 27. 1973

11. saisureuproduaing ngentu and antinupileptic

drugs;

12. Ant1~Purk1naon agents;
13. All the can: an missud.
This could be argumiseﬁ by Harlin, Wbrtia. Klein, and
myself, requiring 9~12 hours if done wall» 3-6 hours

with

MF/iJ

same

difficulty.

�</text>
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            <name>Description</name>
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              <elementText elementTextId="55751">
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            <name>Rights</name>
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              <elementText elementTextId="55752">
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          <element elementId="48">
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              <elementText elementTextId="55753">
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                  <elementText elementTextId="103746">
                    <text>a~mm&gt;‘-5.

..

.

.. “my...

.HV—pw‘

‘7:

n/‘v‘

-

..

.v‘.

.-.,.,;

....

.

1.

raven-u

—-y.~nw."(‘~

April 27. 1973
Dr. Gra¢o Pierce,
Orthe Research Foundation,
Route 202,

Barihan, R.J. 08869.
Dear Grace.

Enclosed is a signed FDA 1572 fbr the OR? 8063
Itudy in Ankara; and the anrricula vitae of Dr. Itil

anﬂ munelf.

'

For shipmsnt of supplies. and far record purposes.
the aﬂdrens of the project officer in Ankara is:
Albuy Dr. Sevket Akpinnr,

Celikkala sokak,

3/10 X13113: ~ Ankura.

Mk3?»
A",

v
:r.

my

A

v
w

best resurdn.

'?r'.-Wnrw

Binneroly yours.

r
:z-x-rs-vu

uh: rink.

M.D.

Prorontqr of Puyuhiatry

ur/id
aunt.

�</text>
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                    <text>7385-65}:
Ami}. 30, 197 3
".x“

-

V,

.

‘:
_,

Dr. Ward

Rev York

vumu.

Pim.

Meal
Her!

College.

10595.

,—..

Re:
:v'mmmumwgrweve.“ourr.,v;4..u«

Deer Doctor

I

Volevke,

3g

ﬂaw.

M,

.

Pim,

pleased to reconend the mutation of Jen
, when: I have known for more than five

am

1-1.1).

yearn.

In 1967 I visited Prague and became acquainted
work and that of his Chief, Jiri Boubicek.
A1 Freedman end I invited both or them to Join our
Department end in 1969 they both cm to work.

V1151:

his

During the“ were Dr. Velevhe has made
eignifieent contributiane to our study 121-0ng in the
effects of psychoactive drug: an brain function,
Mleuerly in our studies of ambit, heroin. and

”ﬁnk“.
He

worker.

in

I

e.

am

reeponnible meetigetor, and a diligent
pleased to recmend him for promotion.
Sincerely yours .

ﬂex Fink, MD.

Mfeemr of Psychietry
WI 13

�</text>
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                    <text>7333.592
Herch 26th. 1973

ma

PM,

HID.

g

Cheirmnn, T.A.P. Comeittee,
New York Medical College.
Greenland: Hospital Genpue.

Valhalla.

N.Y.

RE: Dr

Durﬂb

Deer Doctor Fianna,

I take greet pleeeure in reacunending the promotion or
Dr. Rhee Dorebueh from her present poeitioa, Anni-tent
Professor, #0 Aeloeiete Professor, in the Department of
Peyehieﬁry.
Dr. Dornhueh has worked'vith we fbr
years. During this time I heve antten to
es e researcher end en e teeeher.
As

more than
know

her

five

ability

e teacher, the he: tenant cleeees in the reeideney

treinina progren. in experimental peyehology, epplieetion
of eteiietice to peyehietry, end seeeione in neurophereeeology.
I have exvuye been pleased ta cell on her end heve fauna thet
she in well prepared enn well liked by the students.

In her research ehe has made significant contributions
in underetending ot’meeery function as eltered by electroconruleive therepy (30?). About three yeere ego Dr. Freeémen

end

I

asked her $0 help an with our etudiee of eenndbie. Eur

oontributionein this work have been significant end the is
the principal inventieetor in her etudy program.

new

She is qnelified for the rank at Asunciete Professor‘by
her training, experienee. yublieetiane, teaching dbility end
experience, and releerch leaderehip. I heartily reeamnend
her fer proactien at this time.

Sineerely yours,

ﬁnk. MID.
m
Proteeeor of Psychiatry

“Ilia

�</text>
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                    <text>738B~6h2

Dr. E. H. Terry.
Pharna Research Canada.
250 Hymns Boulevard.

Ltd..

Potato Claire 730.

Fqu .
Dear

Mt

Skitch,

It

was a pleasure

talking to

ynu yectcrduy.

In 1971. and again in January of this ynar,
was asked by the Directer of Beaaareh at another
Enropoan company to put-my thoughts an the needs
psychaphnrlncalosy on paper. I did so, and the

I
or

enclosed notes reflect my thtpking o! a ten’months
use. In rouregding this, I would mats so few amend~
manta that tha text is easenticlly my present Opinion.

I trust this in useful.
aincorQly yours,

Fink, 3.9.
Professor of Payuhiatry
Mun

Hr/id
Rue.

�</text>
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                    <text>7353~6h3
A13141

Mr. Jonathan
Box 8&amp;3,

2?. 1973

Fink,

Rabat. Union,

Colby College,
Httarville, Mhina oh901.

Dm Jon.
(lain;

Maw months ago

some

studies of

of ”1.1mm.

M.

are enclosed. and

TM

Peter
as u

Crown was

interested in

emu-1m to the effects

tint time he wrote up the not» which
“muted the weanpanying papers.

A: man knew, I am not enthusiastic about
encouraging you in m. but if yon are reading the
perhaps mien notes would be of me help.

51m erely ,

uflid

he.

literature.

�</text>
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                    <text>7383.6”
Avril

27 . 1973

Hilton Hawaiian Village.

Rcmlulu,
HON8.11 0

Gentlmen ,

I regret that I an unable to attend the
APA meeting. and wish to anneal the
math on my behalf for arrival May 5th.

forthawing
reservation

I as: «winning I. copy or the prepayment voucher
whmh may
checking yaw rewards mier.

we

Thank you

far your cooperation.
sinceroly yours,

Mu Fink. Md).
Pratt-sew or

thntry

19/13

we.

ea. to Tran. Consultant... Inc.
1025

Comticut An. mm.

mmmn,

13.0. 20036.

�</text>
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                    <text>731-6501

Ayril 27. 1973
we cmmeﬁ May,
06st lavieory Brunch,
lGASS.

p

'Vlg—w

Plrklcvn Building,
5600 Fishers Lens.
Rockville, ﬂhrylend 20852.

A‘I'I’l'T'AIK"":;-1‘n‘.

v:-

n

Dear Hr. Ehrdy,

ﬁt

.
:nﬁn,‘

«iv-w:

my

me

y
tan.-

7-5".,7'r

var-we?-

7
WV

w".

.
w

V”

are vritina in reeponee to e letter from Mr. C. J.
ﬁeretton. Deﬁed April 23rd. Previeuely. we have submitted the
l9Yl-72 fineneiel statement end e schedule of eelery rates
we

(115m

1, 3).

2. The Aeeoeietion'n policy regarding subsietenee
allowance while employees are an travel statue follows the
prevailing policies of the New York Medienl College. Thie

provides full reiabureement fer ell necessary costs at bohel,
meals. and bunineee telephone. Fer hotel neeoumodetione
exceeding $28 per day. or a daily meel ellowenee greater than
#18, prior pea-mission

.r-mmn’z

2-

*- required.

1b: edbeietenee on oversee: tripe. the policy has been 325
a day. at iteeieed reeeipted expenditures. Effective January 1,
1973, this basic daily rate was increased to $35 e day to account
the changes in exchange rates.
under the reqneeted extension of the contract
are requesting funds fur h visits to Athens
1 viait ta Kev York by Iﬂbcontreetor. All
end
by consultants,
New
York and Athens. (In eetehlishing travel
between
tripe are
haste, 1e note that effective may let, the round trip air fare, J?K
ta Athens. in .805 until may Slat; and $927 from June 1 to
h.

Han k2-70~98. we

seatedber 30th). we entieipete
and 2 after septeﬁber 30th.

2

tripe during the

summer

period

5. we have processed phyeiolosiael ante sent by the
1972. This processing includes:
eubeonlreetor beginning Deceﬁber

l,

(a) Date reduction end primary ennlyeie ueing an

IBM

1800, situateﬁ in Stony Brook. 3.Y. which is funded by this
Association. The Associexien he: submitted monthly statements
fur the personnel tine end identifieble euppliee need, and has
to 1 mm rate of $150/mth or sac/hour. vhiehever 1:
lower. fbr the ansoing analyses. At present. ohergel will be
$600 for the period January 1 to Avril 30. nnﬁ.we hi?! eneuubered
$300 to June 25.

mm

�Mr. Clarence Hardy

April 27. 1973

~2—

(b) Ststisticel moccasins of the large dete matrices
been carried out at the Biomedical Intonation
he:
produced
Center
of the Rev York medical College in Valhalla, NJ.
Processing
In this processing we have niacin-sod the Rear York Medics]. College
for time on their IBM 370-” ct hoe/how.
(e) Wins the next 8 weeks, edditionel computations
cede
be
will
at the Few York Medical College, and sdditionsl
statistical programing will be needed. Additional help will be
provided by prom-mere at 8'0!!! at Stony Brook, or e private
consulting firm in New York.
For the mining period or the contract end specificsily
with 1‘05er. to the extension, we are requesting additional funds
to continue siniler expenditures. We nnticipste incrmed hours
on the IBM 3007‘136 es the fine]. ststistioel analyses are requested
by the ecientists. In our celeulstione ve ere entice. 10 hours
machine time st $100 an hour; 3750 for programing services; and
$1250 for personnel costs and
1800 cm.

m

To

utilise the facilities of the subcontractor et the
we have provided a. full library of

University of Athens,

stetisticsl programs usable on the 01114300 computer st that
University. Bone statistics]. enelyses of the behavioral date will
be done by the cubcontrector under our supervision st hourly retes
equal or less than the rates noted shove.
I trust this information is helnml. end I look forward to
meeting with the contracting officero on Key 2nd.
Sincerely yours ,

Mex

Fink,

14.13.

hecctive Director

RIP/13

�</text>
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            <elementTextContainer>
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            <elementTextContainer>
              <elementText elementTextId="55822">
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              <elementText elementTextId="55823">
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                    <text>7383~639

April 26, 1973
$0:

Arik Brisaennan. H.D.

FRQM:

Nix

rink.

M.D.

aunJECT: Viﬁ Drug Dupendenae ﬁrentnent Center: Opening

of ndbulatory treatunnt programs

The Dare, outablishnd in July. 1972, first developed an
inpatient treatnnnt unit with «aphasia on the grentmnnt of
opiaxo dependent vutcrnns. ‘Effﬁﬂti?! Ayril 23in, 1973. the
name

is

new oxp¢ndin5

it: program

fully ambulatory basis.

to trett

auch

patient:

on

s

(a) aggggitien awnilnbla.
The staff naw offers intoxirication. psychiatric
counselling, group thcrupy and vocitienal counselling. mathndone

and lavamathadyi unintenanca. and dcaonditioning therapy axing

eyelalocinn.

to the

DDTC.

On

Thane

services urn afterad to patients admitted

a fully ambulatory bani: tho

DDTC

will accept veterans

tar adbulatory detoxification, induction in

nathndone. psyuhistric
and vuontionnl eounuelling, and genial can. work.
(b) Admisaian ggggegpro.

to the

Vctaranu may be ancaptea to thc progran.by application
at ﬁbrthyort, by calling:

V13

or.

261-hhao x 22h? (Dr. Brissendcn)
269—6600 x 2285 (Dr. amazon)

Paticnts will be such by a phyiieian, and an anaesumnnt
of their drug depandanny made on the basin of history. physical
examination. and, where appropriate, urine sunny and nalaxonc
(or nnlarphine) challango. Admission to outpatient or inpatient
pragrun will be maﬁa by the admitting physician.

�</text>
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            <elementTextContainer>
              <elementText elementTextId="55832">
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            <elementTextContainer>
              <elementText elementTextId="55833">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                  <elementText elementTextId="103751">
                    <text>w.~&lt;v

E

1

.

a

....

.,

.-‘-..-.~

\

‘

...

.,.,,

v.

.

v;

vv- ~wwm._v.wu-.._w.. .... 7‘«ﬁnivmwvnwwuwﬁw..-w-\4»,v.«.h.v

.

‘

r.,

u.

-V.»~..m.

7333-630

,

‘

(.7-

.

“Tn,“

,..t,.;.

”7

..ﬂ.

,_.

.

.7,

_

r:_,‘.,..vriv ..r“

April 26, 1973
Dr.

a.

C.

Lairy,

Hopital ﬁanri Boungella.
1, run cabanis,

75-min 1”.

France.

Din: Banter nniry.
Enclosed

1n Mhrncillo.

is

my

ragiatrntian far the fartheoaing matting

I submitted un ubstrsnt to Profeutcur
J. Cudilhac. unﬁicipn$1ng tn axhibit. A: the onclnued
latter indicakos, I have had to «hangs my plans becnusc tho
exhibit in no longer tangible. I vuuld be grateful if you
aan still coaaidor thin dbstrnct for ; yrescntszion in
Btytuubar; I rcccgnizc that tbs deadline data at April 5th
has already passed. but I trust an cxneptioa can be mada
sinao this dbntract was actually submitted many months ago.
Same month: can

Truating to your 59nd officcn,

I remain,
Sincerely youra.

”at. ”CD.
m
Prnfccuar or Psyahintry
33/14
Eha.

,

.7}.

.7

.

�</text>
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                    <text>7333~5h2

To:

Stanley F. Kellen.

FRQM:

Mix

3mm:

Visit to ma. Central onion, yak/73

mhe

Fink,

M.D.

M.D.

I

met with Mr. ﬂbxhisht. Dr. Kata. and Dr. Tucker.
following ia a tununry cf vast I believe VI: 3 most

turntable wasting.

l.
levwls

basis

The funains

until June 30th.

mi 20 9T8.

for the
and

nnwc

will remain at present

is refunded on a sustaining

2. The Central Office naaunns that this allocation
is anyplanaatary to the‘basiu funding for a ward. fur

22 bad: they ﬁbula assume 20 FTR. or which 10 would be
"visible" and 10 "invisible". It is thnir imgression that
an allocation from the Director ai Harthport or 10 3T8,

it visible, is

country.

above the average of ather units in the

3. Our procedures fur admission of patients on an
ouﬁpctiant basis, using either 3 F38, at a short form
admission and an innsdiatc page. arc both acceptdble
procedures to tbs VA.
h. Flbr alcohol pragranm, the Ecrthport van is
.111th tax funding in fiscal 1975 (July 197%). Ram.
because 71 Korthport and ho othcr cantor: htwa bcen clamoring
for support before 197h, tho Central Office has proposed
ihnt $2 million dollars be allocated at $50.000 per unit

for progrmn and pilot work, effectivu July 1. 1973. Should
this rcquont be approved, Horthport should be notified by
thn middle of may.

5. Th: dclay in the construetion of facilities in
ceasiionnd by tbs lute dotignniion at V1 Ncrthport an a
DDTO; and tho unnsunlly largc reqnnnﬁ. When the modified
roqunat van ravicvad in withington, it vns approvnd. sad
they know a! no doterrant t0 tho caupletion of the renovutiona.

�Bunnlay F. Yellos Men.

Aywil 25, 1973

~2~

6. Bath Kr. McKnight and Dr. Tuckar emphasized that
they ware very much interested in having units exporinant
with naw ways of tronﬁiag Viterana. Thay'vure partieularly
intaracted in a halfway house. and noted that thnyrhud
aahievad an interprttation by thn VA Couasul that VA funds
aould he used to dcvnlap a halfway house. @hay are
preyared to fund such a program, SV3y tram the central VA
installation, as a "aclfnregulating therapeutia cantor" up
to a level of a m. caemtca $6,900 per you for 1m
oquvnlunt at 20 beds. or $120,000; plus an initial menu
rueurriag cent of $20,000 tbs runovution. (Both ﬁr. thhight
and Dr. Tuakor separately «urbanized their internut in such
a davulopnnnt. and than I asked Br¢ Tucker vhathar he thought
va shoula embark on Iucﬁﬁa program, ha indientod Shut he
would be delighted).

a

7. In our ditcuasion, Mr. benight led me to
undarstﬁnd that in determining our budget far the DBTC
thny ware using as guidslinas h—G detomiriantion beds at
$35 a any, or $12,225 per annum; in tbs outpatient dapartmnnt
$5-8 a visit up to 20,000 visits per year, with aa additional
allowance a! one stuff position far every eight visits per
Guy. These enlaulations bring our allocation to $2h7,000
a; a recurring budget attentive July 1.

MiliJ

93. t6 Dru Shaman

Na

Kiaffer

�</text>
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                    <text>TSSB-éhl

April 25. 1973
Dr. Herbert G. Quushan. Jr..
Degsrtunnt of Haurology.
Albcrt Einstein Gallant at Mbdtcinc,
1825 Eustchastor Bond,

Bronx. a.Y.

Inn: Doctor Viuahan.
announeeunnt in Biamadioal Nave of rdbrusry. 1973
reported that ”Shock £harnpy aan produce tons cellular
disruption-tullawing largc uuuhcrs of sneaks. according to
Dr. ﬁafbert G. Vaughun, Jr.. associate prafesaor or
nourology at Einltcin Modictl Eahool. Bronx. N.Y. Same
eonsider 100 a large number. ethars stop at 12”. I an
editing tbs pwouaeding: at a eenfaraane on the Paychdbiology
a! 30?. nnﬂ.vnu1d like to auannnt tbs reports with any
dﬁxn 13 this rosnrd. I am writing to tax far the citation
uyon which the quatatioa is btsod; or. if it 1: unpublished.
I vauld,)9 grateful for a summary 9r description of the
proaeat Iueh as any be available.
An

Thsnk you

for your autistcnna.
aincarely yours,

Mb: Fink. 3.9.
Professor of Puychintry

HF/ij

�</text>
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                    <text>731~6h0

Avril 25. 1973

mm Chung.

V.A.

Hoepitel,

Deer

Art,

aepnlvede. Celitbrnie 913h3.

I received your letter Just on I we: signing the
enoloeea letter to so to oil the participants in the
conference. I think it will answer your Question regarding

the publioetion.

I en not em all surprised theo EIMH hes reacted as
they have with regard to your grant eppliontion. I am
sure it in no eoaaoleoion. out Halter Bremen and Richard
Abrams who also submitted applications as e result of the
stimulation of our conterenoe. also home had approvals
without funding. Somehow one reacts with more feeling
eboum eueh a response than one does to a rejection.
I would not know of the specific reference to the
or Dr. Vinahen, although I do know him personally.
I me writing to him to eat for the citations no that I
any try to underetend the relevanoe of his observation: to
clinical convulsive therapy; You may be pleased to know
that Just e few days before your letter I was invited by
the eaitor of the Journal Biotagianz Phyakiatry to submit
en editoriel on e motto: of my choosing. The editorial in
"How Shocking is ahook Therapy!” and ethemptn to bring to
the attention of the reﬁners the unusual consequences of
our language, pertioulerly when the phrase "shock therapy"

work

1' made

It

ﬁnk,
“I
Exeoutive Director
H.139.

n:
u:
‘a'n'

-

-1»7&gt;'W

:enmpz.

36—1,

“A;

best resents,
sincerely yours,

m.

:ﬁ‘1'2r‘““‘v:“

in alweyo e pleasure to hear from you.
My

'

‘1'

“MD. .

Psyohobiology Research Leboretory.

MFI13

Rae

�</text>
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                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                    <text>ram.

&lt;

L-a

wv

amp:-

run-var

:w

:91va

Wr‘ﬁrﬁrx'

Arm-w

73513-638

April 2”, 1973
Professeur J. Cadilhae,
Faculte de Medecine d9 Montpallicr,
Pathologie at Therapeutiquc Gannrulcs,
Institut de Biologie,
Mbntpellier, France.
Dear Frofelaaur Osdilhne,

Since receiving your letter of Januury 22nd, I
have fbund that it would be too difficult to provide
the exhibit which I baa planned to make at the
International Congress in Septeﬂber, an&amp; I am writing
to ask tau to withdruw the abstract and the ezh1b1t¢

I look

Harseille.

forward to meeting you nevertheless, in

Sinceruly'yours.

MAX Fink. M.D.
Professor of Psychiatry

NF/id

�</text>
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                    <text>7383—637

April 2h, 1973
Mr. James

J. Eberlein.

Pfizer IMug

235 East hand Street,
York. R.Y. 10017.

New

Dear Jim.

It is with rcgrct that I reqnnut withdrawal of
thn exhibit ”Drugs, EEG. and Behavior” tram the APA
ﬁhia year. In reviewing tbs material which we have
submitted, I have bacon. concerned that the information
praaented could be misinterpreted, and not enhance
our pwogran.
I

am

moat

grateful for your

many

excellent

suggestions 5nd the support whieh yen have given

prosoet.

this

I hnvc taken thn liberty of notifying the APA
ottiee and am analosing a copy of my letter to them.

Again,

my

thanks fbr your cooperation.

sincerely youri.

Fink, M.D.
Professor of Plyohiatry

Mix

ur/id
Ens.

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April 2”, 1973
‘1.’

Mumzv—P‘C-

E

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K.
MW
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W

Hernia, Ina...

Avenue,

N" Tart. 8.1.

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Wm,

difﬁcultiu with
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maimed and
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Bonnier”,
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the
«£15306. Booth 320
man.
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V111 be unable to
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‘51.

ambit

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UM).

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�</text>
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«W‘~«.

v-Iwmt -,

me...

».n;, n

w

-

1-...

7313:09601'

April
Alin Giles,

2%

. 1973

M.B.

Scientific Development Group
E.V. Orgsnon
Oss, Holland
Dear Alan,

I have the two tapes and have put them sside until
data for you.
record
can

we

Dr. Lange's problem with subjects becoming so sleepy with
the low doses of dissepan is most interesting. In our heads, doses
up to 10 25 here been well tolerated and only rarely have we had
subjects descend into stage 3~h sleep, to be undisturbed by the
buzzer. Usually we have allowed these periods to continue to the
end of the fifth minute, when the subject is alerted by verbal
cues, with the request to open his eyes for ho seconds. If this
is unsuccessful, we have allowed another period (up to 5 minutes,
but this has occurred only ones) when verbal questions are again
tried-~ if unduecessful, the experiment was terminated and the
session repeated a week later. My staff can recall only a few
such occasions-— with dissepsn 10 mg; doxepingHCl, 25 mg; and 20
mg imiprsnine.

ours,

we

Should it prove that his subjects are more sensitive than
should investigate the phenomenon further. (What is the

ambient temperature of the room 1 How active is the air circulation
during these experiments~~ could the room he considered 'stuffy'.
encouraging sleep 2)

we

I have already cabled my willingness to use 10
have already carried out some pilot studies without

mg

amitriptyline--

difficulty.
trip is as yet

are you coming to the U.S. ? My own
Shapiro is leaving this week~end for s meeting in
when
and
we reached Jim Porsek, he indicated he would
Switzerland,
meet Don there. I am awaiting approval from HIMH for our Greek
extension before scheduling a return visit. Will write as soon as
when

unscheduled.

I

know.

,

My

Don

best regards.

Sincerely yours,
Max

Fink,

M.D.

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                    <text>"Tamar-n

._

non-um.rn.-acxuw

.
—

.

,

7383—6336

April 2h. 1913
Richolas A. Face, M.D..
250 East 73rd Street,
ﬂew York, N.Y. 10021.

Dear Boater Paee.
n

‘
.

an;

.m;r4vnnwxl

Your lettar is in error a I have not acccgted an
invitation to participate in a meeting st Dr. Campbell's
hamo; and t: I am not a voting residsnt in New York city,
suggest you not list me as a participant, supporter,

contributor, or cantultant to the

Biaggi.

campaign

of

Mk.

Sincerely yours,
r'

~

:—-7—

"-wn—I-u-

Mn: Fink, M.D.
Professor of Psychiatry
HIP/13

�</text>
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                    <text>m...

War:

a:

.--.;...As.,;:»

g.e-

Trim-63h

Hodical Lieansing Basra.
atate a: New York.
Twin Tavuru. 18th Flaor.
99 Wishinsten Avenuc,

Albany. R.Y. 12210.

Re:

E.

Pitts

M

B.

Gantluncn.
am Flttlcd to vrita on.bchalt at Dr. Bbrman Fitta.
I hurt known since 1967 in his many roles of increasing
responsibility in ¢liniea1 research at Pfizer. Inc. As a
consultant, I huvn had many opportunitiou to meet vith
him, to unseat nadiaul studios and cat: with him. and
becaun aaqnainted with his knovledgo of clinical madicino.

when

I

Dr.

Pitt. is

an outstanding

cliniciin, with a

keen

interest in and aunrcnall of the yrohlqns of patient
care. dingnosis and trontnnnt. Ra in warm. friendly, and
congenial in his interpersonal relations. and ralidbla
and thn'ghtful in axercisins his professional responsibility.
In I? relntiunlhipu with him, I 3&amp;3 reflect on no oxpcrionao
or quality of personality that would limit hi: full
endorscmnnt fbr licensurc in medicine.

I an pleiscd to undorle his applicatian without
reservation.

v-

Singeroly yourt,

aﬂ.7=:l__";"

'5
.2=),v,:

Jan

mm...”

Fink, M.D.
?rofnsaor or Ptychigtry
Mb:

MF/id

�</text>
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                    <text>“ﬁr-trawwwmx!

zvc-rmn

«:1

‘

.«

7353-635

April 23. 1973

Yell...

To:

Stanley F.

13014:

”M Fink, ”6D.

SUBJECT:

Hbdifion&amp;1on

M.D.

er Esau

2312

Enelosod 1: a drawing prepared

at our ruqnast by

his couwartarl at the rhoilities Plnnning
modification of room 2812 an three
the
affine. In:
simple ldboratory apaeea far phyniologieal recarding.
R. During and

principal elqmentn are walla. modification
of ‘1r handling. lighting (which is incandescent rather
thin fluﬁraacent), and a change of electrical wiring,
such that each roam is on ; separate eiruuit breakur.
The aatinnﬁc is $1.500, and from my past experience
should be quito aeeurate.
The

Please advise us to any further si§?a.

ur/13
Baa.

�</text>
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                    <text>\V

-'

w‘rv-«mwm

a
17

«Qua-"m

W‘dw—"ﬂ

73SB—616

April 9th, 1973
To:

Stanley P. 1911‘s,

FRUM:

M31

SUBJECT:

Lester Shapire,

Fink,

M.D.

M.D.
M.D.

pleased to reeoumend Lester Shapiro, M.D.
fbr promotion to Associate Clinieal Professor in the
Department of Psychiatry.

I

am

Lester since 195h. At that time I
eetive in the Nassau Heurapuyehietric Society,
the district branch of the APA. Lester was one o! the
principal leaders in that organination, end it was
largely through his efforts end encouragement that I
assumed an active role, leading eventually to the
Presiaency in 1959. Throughout that period or time,
and subsequently, I found Lester's advice to be logieel.

I have

became

reasonable,

known

and

his

Judgment

excellent.

Subsequently he took an active interest in the
In the county he has always ahnwn an
interest in the training program: for General Practitioners.
I have known him es e preetitioner, to whom I have
referred eases, and Iran when I have received enquiries.
In such clinical eitﬂetienu his Judgment we: excellent
and his point or View eeleetie.

APA

itself.

During the pest six months I have had numerous
oeenaions to discus: our training program with him.
Again, his eeleetie liev end good judgment has been

repeetealy aennnstreted.
In

I believe him to be a fine elinieien sad teecher.
mind he satiet1el all the requirements or en

my

Antoniaxe Clinieel Proteeeor.
MFI13

�</text>
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                    <text>ESE-$86
Much 27th. 1973

mu»,

we:

Manley F.

FROM:

Ma

mm:

Window: Coutmt

Fm,

24.».

14.13.

handing the roply whieh in mm for:
3.. Ho ”upon".
2. All the mad: at m nm are and for
rumination. Aw mum}: activity is financed

and
tram
by

Univunity funds.

3. no momma.
1;.

(a) For 1973-73. in have

«may to member;
has 105-4105 capacity. Our

at

891

capacity. [Capacity ..

1205

man

utilised the

beds of

me

and now
{mam-hm;
pmjmuon for April-Jam is

1005

21

m].

For 191'3-73 we are projccting 219-30 bod:
aver capacity being housed in mm man.

- the

staff visits: Putin“ visiting staff as
Mystique: ammc BS-BO/vnk at this time, increasing to
80-100 by June. For HTS-7%. we: anticipate 100—150 cm
visits/wok.
(b)

(a) Contrmt

am:
am.

visitu

to Dr. 8. Kieth:-

new in date. and none projected.

�</text>
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"hazwm'ﬁ-lvf?

/
n

.

HEB-577A?

Lurch 12th. 1913
To:

sunny 1'. You”,

mm

ﬂu: Pink.

mm:

American

$.13.

194.1).

Pswhcpnmmsiul uncut-Men

m

Dr.
ﬂak was eluted President or the Algerian Psychoputhologictl Auceintien at in: annual meeting in March.
Inoculation in in its 5%}: you and has 0. Worship 01'
.250 pmhiatgviats, pmheloguts and kingdom scientists who
met madly ta discuss mutton: or the relation of

m

to behavinr. The 1971: topic: in
evaluation of payeholasictl modiﬁers at behavicr".

psychology and physiology
"An

Dr. Max Fink is Professor at Payehiam 1n the 3mm:
acumen Center and investigator 1:: studies at the mutton
or mmphyaiclogical mum-ea to hehavior, and muzzle
antagonists in the treatment of opiate (immense.

13/13

�</text>
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                    <text>~13

r'wwm'vé‘rw:

7%8—56183

mu 5th, .1973

9'75“”

am

-o.‘1-,:ad'm-

«re

yaw-7‘

'

WWW-'Wﬂiay-

You“.

To:

Stanley P.

W:

m Fink. 24.1).

SUBJECT:

Norton 0.

miller,

Md).

35.1).

—-‘mw»§-w

I an planned ta write in support of the recamendntion
for “mm: for m. marten Miller.
Prior to wining this faculty, I had occasion to work with
Dr. Miller when ho was an administrative leader at the Nation's.
Instant. or maul 3.51%. in mm role I foam! him unusually
tnumgont. innovative, and sensitive to social 153m; of
mental health.

emit:

E

81m. Joining the faculty last
I have worked with
number of comittees.
in the training program and can awar,
On each occasion I he.” bun impressed. by his induatry, enthusiasm,
smdrill. and; his ability to bring ta both the taaching and

him

aspect: of our work, a brand perspective and s
Maintain“
sensitivity.
Wedwith enthusiasm. accepted the challenge of the teaching
He

._

.,

~.

.‘

I

am

pleased to recommend him far consideration for tenure

tin was or the Stat: University or New Yam-y a. I
conﬁne“ mm: In is nrioualy counted to teaching as a
under

and
V

to this mimityc

mm

an

cum,

�</text>
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5

E
-

mu»:

15"."‘nlvai'Pk'

q;

7383-53083

February 15th, 1973
TO:

E

FROM:

.3th

1'.

Gone M.

smith. Mad).

”fall“.

24.1).

m Fink. Md}.

1' have read the
publimum of 132-. 83111211, and his
emiculm vitae;
If. is difficult 301- m to envision an active mew
19
far Dr. 831th at this timu E1: 1mm.“ in opiatan
in their analgesic componmt, and in this ha in

ml?
m
helpful in

a.

docs not have the exparimee which vault! be
programs in treatment. or :1:qu of
eluted opiate angina-nee and multimsubstma abuse. Thu
closest 1: the
or ”Antecedents of toms. drug an"
(WW9). This is an 13:99th magma which my ’0. of

export.

our

mam

am

we: the impression that tho
tannins capable of undertaking
drew
and should we with
1::

inter-at. Homer, I m

university

ml:

surveys.

has

their participation

«Wat's: teaching or mesmh. could we not. get
thair help without Dr. smith!
1m

247/13

m.

�</text>
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                    <text>u- 'm“ n»...- w—
.A

1333-5183):

hbnnry 6th,

1'.

Yon”,

T0!

8128211.]

m”:

m Fink, NJ).

8W:

Departmental

1913

”.13.

Ming

I tarot that I

muting
Win}.
momma tn

M

cannot attend the
February 8th.
I had

many, to locturt 81:.
u .Vimunt': {lo-pita;
Manny
Yerk on nut-zone ammonia”.
on

gar/1.1

3:3

in

In

�</text>
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-\-~

vi

:
mu

.n'.

.-—,~m

731-63h1

:
v,

---v:

.
_.

April 23, 1973

xrarwm:

Mr. Clsronos Hsrdy,

Cost Advisory Branch,
16A55.

Psrklsvn Building,
5500 Fishers Lone,
Rookvills. Msrylsnd 20852.
Dear Mr. Hardy.

In response to our discussion on Fridsy, I so
pleased to enclose two itsms thst you requested - the
annual financial report of tho Association dated June
30th. 1972, and a copy of the Hutch Blot payroll of the
Association.
The

payroll

supplenontsry

ls

it.

for the Association. A
for the quarter from the subcontract

I would be glad to send you a copy if you
For your information, the titles and salary

dun us and

rsqnsat

list

list is

ranges are listed:

Fink, Exocutivo Director
Thion, administrative secretary
Snapper, progrsumer

n,

n;

,

.

Poinior, rosoaroh assistant

_

V

assistant
Kurss, research assistant

4

__

i.
.

my.”

”ma-.2

An,

.o-

..

.;
’41-"

“7503‘

V

i.

Those

~

-

~

- $6,800—$9.600
- $6,800~$9,600
EEG
~ $7.2oo.$1o coo
Garcia,
technologist
workor
Schwartz, social
- $11.000-$15,000
(sdninistrstion)
swanson. psychiatrist
- $27,500-335.000
sslsries are consistent with the sslsriss now in

Sibonoy, resenrch

N“

-

EEEEEE

(by negotistion)
$9,000-$13,000
$12,000
$6,800~$9.600

force at tho Haw York Mbdiosl Collogs, whose sslsry ranges
have been used to nogotints sslsrios for the Assooistion.

'4‘?"

I trust this information is useful.

A
.,
w.

-A

«

Sinooroly yours.

ivwwur

)

Mb:

Fink.

M.D.

Exeoutivo Director

mrlia
Eno.

�</text>
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April 19. 1973
Mr. &amp; Mr:. Henry retool,
7 What 8lst Stroot,

New

York

City,

E.Y.

Dear Hurt: and Hoary,
An I thumbod through my’nail the other day, 1nd
sonnnod o host of Journals and Junk. I saw the uncle-ed

covor, and without looking at tho credits
immodlotcly

I

it

do not

was can

of your friends;,

knew

think the roproduotlon does his

work

Justice. but I must admit that this kind of op—ort
in interesting. Perhaps «won more so is the fact that
I can recollect of no other modern pointing reproduced

on the cover of thin Journal for usny. many months.
They usually use a olaasiaol. representational type

art.

of

Martha must have told you that vo are Joining
you in Iuyporting a second house. w» have found a

cottage overlooking the voter in strong’s Nook (Betauket).
is tvolvo minutes from.my office at the Univorolty.
A: MLrthu says, it in possible to stood in the middle of
the living room with a dust cloth, turn 360°. ond have
completed the cleaning.

Th1:

I trust the family are wall.
my

boat regards.
Sincerely youro.

Mn: Fink. M.D.
Professor of Psychiatry

MP/id
Eno.

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v
V

'1'.“

v-

mmc'rm‘mr

'

7333-5330

April 19. 1973
Dr. Richard Abram: .

1h2 Columbia Heights.

Brooklyn,

ELY.

Dou- 10101:,

I have reread your contribution to the EST
volume. In the: context: of tho two reports by Banter,
copies of which arc ”cloud, it might ken thc
value up to date you would add a. postscript,

footnote. or s
the contaxt of
of course, add
place. If you

would be most

it

paragraph, placing their work within
your review of multiplo ECT. We will,
the (citations at the apt-mint:
could do so within the next. week. I

grateful.

w but regard...
Sincerely yours ,.

m: ﬂak.

14.9.

Profane:- ot Psychutry
MI 13
Enos .

�</text>
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                    <text>7383-627

Amril 19th, 1973
Dr. Jchn R. ﬂushes,

Canaultina Editor,

EEG
aWTn-K‘Wﬂw&gt;'

qurnnl,

Book Ravicva,

Northwestern university,

303 3. Chicago Ava.,
Chictgo, Illinois 63611.

4_.‘rl'vl~'l

A;
w.

.
,rv

,r-w

v
—«

v'wp‘I-ﬂlnmsmr

=-—u:—.v.v,

W 30m.
I have received the voluna “International Review of
Reurubiology". and look tbrvurd to reviewing 1t fur the
EEG Jburnul. I have a tow chore: to do over the noxt few
vuckn, but should got to it during late Mhy, and helluva
I can must your July daadline.

Thai-v.11"

thy

err-"a

v-wo-

thank: for thinking of no.
my

4‘5'

den:

best regards,
Sincerely yours.

woman-UV»:

Fink. M.D.
Professor of Psychiatry
Mb:

“/""‘.‘.‘

gnmlr

.5
up.

warm}

A

«2—

v.:W’u-'&gt;¥"‘:--I..,-r~rr.~

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�</text>
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                  <elementText elementTextId="106670">
                    <text>Sent

I

to: Richard

Alfred Freedman, M.D.
'Martin A. Green, M.D.
‘Martin M. Katz, Ph.D.

‘

‘

A‘V’

Prof. Luigi Velzelli

Abrams, M.D.

Rhea Dornbush, Ph.D.

1

:

‘-

Geller,

M.D.
Irwin Kbpin, M.D.
Jan Volavka, M.D.
Giacomo d'Elia, M.D.

Anne

,

Mayra Williams, Ph.D.

Steven Zornetzer, Ph.D.

Williams,

M.D.
Steven Secunda, M.D.
Seymour Kety, M.D. and James McGaugh, Ph.D.

Thomas

731-633

Agril 19, 1973

walter Essman, Ph.D.
Arth‘ur Cherkin, PhQDO
Dr. Adrian Dunn
Alex ICE-ream, NJ).
Joseph Mendele, Md).
Gordon Pryor, Ph.D.

Jan-Otto Ottoson,

M.D;
Joseph Schildkreut, M.D.
Iver F. Smell, M.D,
Joyce D. Small, M.D.

',

Deer

the reports of the
I eu.pleneed to tell you thatECT
are in the hands
conference an 2g; zgxghgbgglggz of
&amp;
of the publisher, V. E. Winston Sons, who plan to have
in Septenbee. The volume.v111 be
will be
published at a reasonable price ($l2*$lh) eand
Sons.
distributed and advertised by John Wiley

the

volume eypeer

and
like to have an upmto~dete title
address
eddrese list for the yertieipente. If the card andon
the
this letter is correct. please initial
academic
titles. If
adding
proper
your
return, after
indicate.
we weuld

there are any ehangen. please
we will tend gelley proof: with the usual request:
for prompt return.
June or July, and know e
If you plea to be away inI would
epyreeieto receiving
temperery fbrverding address,

it.

the

We

are grateful for your participation, and hope

volume

will

meet your

expectations.

sineerely yours.

Pink, Md).
m
James McGeugh, Ph.D.
Eeymour Keey. K.D.

Editors

mr/id
Ene.

�</text>
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                    <text>Av

rm"

‘&lt;

"P

—‘

rrt"‘W-‘?7"‘

memmMn-ywx-

7383.629

April 19. 1973
Dr. William Biler.
Biomndioal Engineering.
Dovnstate Medical Center,
h50 Clarkson Ave.,
Brooklyn, B.Y.
Dear Doctor

ﬁller,

?or tony yours I have had a laboratory for EEG
IBM 1800 comyuter as a proeesoor.
This winter I moved the laboratory to this University,
leaving-bohind my close associate, Donald Shapiro, 0.3:.
In discussing a replooumont for him. he suggested that
I should write to you and ask whether you had some
candidntoa graduating from your progrtm who might be
interasted in computer applications to physiologioal

analysis, using an

signals, particularly EEG and EKG. If you have some
at the M.S. lcvol that you would recommond
to as. I would appreciate roeoiving copies of their
curricula vitae.
graduaﬁon

Sincerely yours,

m

Fink. ”on.
Proton-or of Paychiatry
MF/id

�</text>
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                    <text>TEE-633

April 19. 1973
School of Pharmacy,

The Hebrew

University of Jerusalem,

Jerusalem, Israel.

new Raphael.

um

m

written. and
use since
It has been
have not had my word. form]. or intern-.1, ”strung
your application to the Rational Institute of Mental

I

Health for the study "ﬂmotte Antagonists in Anisotropic
I an writing because I bl" received. inform}.
word that the
a request for agencies
h“
such
contract.
work; and is, this week,
in
doing
Wanted
sending out. form]. rogue“: for bids from individuals and
agencies who have tha background and mutant to do web
a Job.

Mm". m
and.

that

mm

If. yet: have not. heard affirmatively from KIWI.

are

you

intuntod in this mom, I would
mu
write dircctly to Dr. William Bunny at

oxphinina your interest cad «king for
(1 dc not have

Jttfea‘

I

would

am. or I

would

also and the

(mm.

and

same

a.

Dr.

14:. White Home, wuahxngton,

In each letter you
have
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you
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Jam H.

9.0.).

my,

m

m, m.

copy or the

it to you).

letter to

suggest

11' you V1.11, 1341mm,
from no 62: Alfred.

but

that

regards .

ﬂuently yours.
mu:

rink. um.

Professor

per/1.1

at Psychiatry

�</text>
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                    <text>731~631

April 19. 1973
Beynour Kety, M;D.,

Professor of Psychiatry.
Ehrverd Mhdieal ﬁchool,

hissechnsetts General Hosyitel,
Fruit Street.

Boston, Ma”. 02121:.

5

Since reading the summary of the ECT conference. I have
had time to reflect on the eenelusions. I as writing to reise
some questions. not about the summery presentation. but the
tonelusion of the role of cholinergic mechanisms. As I

understand the relevant paragraphs (page: 5a6), the date for
the role fbr seetyloholine ere unimgressive. and do not meet
the ariterie fer relevance, set teeth in your earlier
peregrephs. The persgrsph focuses on the report by Karcxsnr.

years ago I reviewed the data relevant for a
(1) I fbund the ehenges in cholinergie
measures ta have s time tour-e similar to the heheviorel
(end electrogrsphie) effects. (2) Specificity was herd to
demonstrate, but eerehrel trenme and neurological illnesses
did not exhibit the seas eholinergie effeets of seizures.
(3) Using sntilhelinergie drugs, I was dble to reverse the
electrogrsphia and behavioral effects of EﬂT. The date are
not avervhehsing. but teken as a whole, the ante impressed
me that eholinergie mechanisms were relevant to the ECT process.
Some

ahelinergie hypothesis.

objection to the hypothesis is thst entheholinergic
drugs. like Ditrqn, have elinieal entidepreesant activity;
end the suggestion I msde in 1958 that iuiprnnine has
entieholinergic activity also refleets on e eholinergic
hypothesis.
An

In your summary in Doredo Beech. you viewed scetylcholine
ss relevent to the seizure threshold and as reflecting the
widespread activation of neurGBS“, without specificity. I
thought then that your argument use cogent. Particularly,
that seetyleholins. es en ubiquitous trunsmitter, may reflect
the inpeet of the massive discharges oceseioned by the eeixure~
inducing agent.

But

this hytotheeis. of nonuepecifieity, is

�Seymour Katy,
on no more

~2-

April 19, 1973

substantial footing than the suggestions of

epeoiticity. Indeed, the more prudent course may be not to
enticipete which neurohnaor is the more important, but to
reflect on all.
for the role of biogenie amines

who evidence

changes in protein synthenie in

part, this

may

and

is well documented. In
reflect the availnbility of adequate and
BOT

toehnioelly simple

methods of nnnlysie. In ooneidering the
ohelinergio hypothesis, vn are faced by the technical problems
and ineoouracy or hionsaay methods. Such difficulty must have

contributed to the peueity or studies in ECT. I knoV'thnt
this technical difficulty has deverely impeded my studies,
for when we did biouetdye for AOh, we found them too unrelidble.
But. from this vantage point, descriptions of improved methods
for assaying acetylcholine (gas chromatography - mesa
spectrometry en deeoribed by Jenden at the ACE? in 1972. is
an exonple) encourage me that more adequate tests of oholinorgie
hypotheses in

ECT

are feasible.

will be read and en your opinion is highly
valued. your conclusions may influence further studies of
ECT. Alex did not present the oholinergio date well; and I
Your summary

cannot do

better.

Presuming on our companionship, I am enclosing a copy
1966 summary. The data are meager, but may be nutricient
to quicken your interest in presenting the cholinergio date
with slightly more optimism. Should you wish to do so, fine;
thould you‘wish to ignore this point, I will not be offended.

or

my

:
"T

5-12-17va

3.9.

you

The volume in almost complete, and once again I thank
and encouragement.

for your advice

my

":7'1(‘l

':3

best regards,
Sincerely yours,

nmwv-w—

“If
-r=:

Mex

12m

MF/id
Ene.

Fink,

M.D.

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                    <text>'‘g'

ruwvmusuv

K"

731-632

April 19. 1973
James mama. Pam...
Professor at Pmkxmiolm,
University of California,

Irvine, California.

Dear Jim.
0:: first. Mm'of the nun-y. I gent 115 on
to the publish”. In ”wt-caning 1% today. I Milled
in a. fur unassisted emits” in style, reﬂecting
and. an: willingthe format of the othcr mo
Archives
send
on
these
to
the
simltsmous
to
for
mu
.

Win,

publicatian. Please consider than suggastiona, and
let me knew if they are acceptabla.
)5 thanks.

81:3:me your: ,
1h! Pink,
luv/1.1

he.

an. T.

A.

V1111!“

H.134.

�</text>
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..

~-—~-

A.” &gt;vﬁq~~

"‘

3,...‘..

v“ ~...
«

......,_
-

—,_»

v

.m

w
7%.“.”V. re._..e..‘,.,._
..

x

,

1am wempg—“www.mqr
V

crew.“

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731: 09hI
-.L__—._

April 18, 1973
M.D.
Itil,
Missouri Institute

Turan

shoe Arsenal Street
St. Louis, Missouri

_—.h==&amp;:$h

of Psychiatry
63139

._.;‘._i.h“\l;-_e_._‘_‘___..___ge

Dear Turan,
The Association would be pleased to accept grants-in-aid
on behalf of your studies, and will process the requests for
expenditures according to the instruction: accompanying the
awards. In our negotiations on behalf of others, with for
example, the National Institute of Mental Health. we have received
an overhead allowance of 2&amp;5. In other instances, we have
negotiated a flat figure of lesser amounts, and we would be
able to establish an overhead rate for each study.

enclosing sample copies or the forms used by the
Association in its bookkeeping operations.

I

am

to using the conditions of the
director in approving the
executive
award as a guideline to the
Board
may. at its discretion and
expenditure requests; but, the
your request, consider modifications consistent with the intent of
the award.
We

have been accustomed

I trust these notes are helpful,

earnest cooperation.

and

I can assure

Sincerely yours,
6,
‘

Max

II

V;

Fink,

M.D.

Executive Director

you

of our

'

\

~&lt;.i_.a..-.._~

�</text>
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                    <text>TBSB:09SSC

April 18, 1973
Turan Itil, M.D.
shoo Arsenal Street
St. Louis, Missouri
Dear Turen,

as

Enclosed

we

discussed.

is a revised protocol of the

The only item

ORF

8063 study

omitted is the collection of blood samples.

They (at Ortho) are willing to analyse samples for car 8063
and for the metabolite. In our preliminary studies, the metabolite
has e very long persistence, and it is possible that it is this
agent that in the active agent. It would be most useful if the
staff could collect and freeze 10 cc blood samples at each
visit. Near the end of the study we could attempt to ship these

under dry ice and if the analyses are done, it will provide
an independent measure of whether the drug wee taken, and
a reference for the therapeutic effects.

records.

It

could also be useful in conjunction with the

I would, therefore, ask

your knowledge of the
My

setting

EEG

you to review the protocol with
and add the necessary instructions.

best regards.
Sincerely yours,
,2?

Max

Fink,

24.9.

�</text>
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              <elementText elementTextId="56113">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                    <text>war-

“pm—M.

—-—

n

.7,

i

,. w. nwnwr &gt;TWV' ‘

-r.v-

W.

-,.—v—.r.n.

v

-unw—
-~w-v:wxmmn€v-VW&gt;—w—

mi

7"

a w 'v/ ‘n—y-uw

-:-w:.:v-.»vuwmw,r—V,VMW ,.

,W

738:092mf

April 16, 1973
United of Omaha
33rd &amp; Farnham
Omaha, Nebraska

Ref:

.

Gentlemen:

I

am

GL6

1387

Cert 01151

writing with regard to the policy listed above,

on the life of maximilign Fink. I should like to verify the
owner and beneficiary of this policy, and ask also that you send
a form apprppriate fbr change, should such be necessary. (It

is

wish that the policy be owned by my vita, Martha 0. Pink;
that she,!and not my estate, be the beneficiary as well.)

my

and

Thank you.

Sincerely yours.
Max

Fink,

M.D.

�</text>
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              <elementText elementTextId="56123">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                    <text>731-622

April 16th, 1973

qu.J.mn&amp;nnq
Cantrtcting Otricer,

hr

mu

char-was

Chief, Centractl Minagcmnnm Bastion.
Grant: anﬂ Contrnnta Manngannat Branch,
Hational Institu$e of thtal Ecalth,
5600 Fishers Lane,
Rockrille. Maryland 26852.

VW4"W¢"L'1‘/“"I"

Dear Mr. Grndvell,
:w-‘m'quwwvr

HQ have been notified by taluphano by Mr. Jack
Johanna of your office thax aur reqnsnt far an cxtansion
at HEM h2~70~98 for six manths bawbnd June 25, 1973 has
been approved by the pragrnm review toam, and that it is
your Intent to fund this request. Mr. Johnson indicated
thut a formal artension will reqnire some time to:
processing.‘but assured us that we should proaoed on the
assumption that our raqnast will be ”substantially" approved
there being same itaau which arc subjact to nagotiation.

-

the assumption that this assurance in substantially
are notifying the subcontractor. Professor C.
steflnis of thc Untvernity of Athuns to proaeed with the
special studies (nusaasnant of withdruvll otteats) outlined
in that request.
0n

correct,
A

vmv

um

If this

asauranne

of tha coumnniention of
natify ma promptly.

is in Jeoparay. or our interpratation
is in error, pleas:

Mr. Johnson

It is also my understanding that the praparationn for
the unsatiationa for the axtennion will require 3 to 5 vuoks.
I trust thane conelnsions nrc aorreet.
sincerely yours,
mmmwcwnnnmm

Max Fink, M.D.
Professor of Psychiatry

MF/iJ

ea. Costa: stefanis, K.D.

�</text>
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                  <elementText elementTextId="106677">
                    <text>7.,4.‘

,,

“MM...” .._.,,......

W.

NV

.

.

7388~626

H

‘

»...,,..-w-w..~u-~T.n-‘Hmy

.»

,

- ~- .

”an

‘

«.wr

r

""

»-

~-./

Agril 16, 1973
mo:

Leonard E. Mbiselss, M.D.

max:

Max

SUBJECT:

Control of drugs on campus from.the University Countel

Fink.

116.1).

namornndum

2/26/73

In response to this llnnrandum. I have dincuased the new
regulation. with representatives of thn Narcotic Control Bureau
of the Bogartnent of Health of Haw York.
Present regulations are being interpreted that individuals
individual labaratories are to be licenssd, rather than
institutions. excepting hospital pharmacies.
and

In tddition to conplying with New York State rnguletione,
applications must also be made to the Bureau of Earcotics and
Dansaraua Drugs. The pwoper sequence for a scientist is to
take application and obtain approval tram the ﬂaw York State
Dopartmcnt of Health. and based on this approval, apply to the
Bureau of Narcotics and Dangerous Drugs. (Depending on the
project, separate additianal applications are ordinarily made
to HIKE, FDA and other agencies which actually supply controlled
substances).
Because of the couple: nature of the regulations, it would
be advisable for the Health Scicncas Center to appoint an officer

with tho rnsyoncihility to: .‘ “maintain a file of pertinent
resulstiona; (a) advise mamhefs of the Health Sciences Center
professional staff in matters of complianca; (3} mnintuin records
of approved application: within the Health Sciences Center; and
(b) coordinate tho use of facilities specifically nacesaary fur
the control of thase subatanccs. ﬁnch an officer should natify
periodically (unannlly?) the ﬁles ?reaident for Health Sciences
of thn status of applications and tho use of contrailed aubutnnaos
in tho institution.

or a single application from a single office
for research in controlloa aubutances is not foasible at this time.
The conuept

HF/id

'-"'

�</text>
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                    <text>7383~62h

April 16, 1973
Dr. P. Gilbert MbMEhon,
Read, Therayeutlc Section.
Departmcnﬁ of Medicine,
Tulane University School of Modtetno.
lhBO Tulana Ave..
new Orleans, La. 70112.

a

"warm-w?!"

nn—uw

man

"'meth

1:21am

I

.2

g

Dear Doctor Mhﬂahon,

is a statement from the Harriett Mbtel. It
underntandlng that this would be paid by the master
account.
Enclosed

was my

,

If that is incorrect, please send it back to
will arrango far payment.

me

and I

for your kind invitation and for the
ylctures which I received this morning.
Thank you again

Sincerely yours,

Fink,
Professor
max

Mylié
Baa.

M.D.

at Psychiatry

�</text>
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                    <text>WW

731-623

April 16. 1973

W,
m,
5600 Fishers Lane,
aockville.

Maryland 20852.

Gentlemen.
Attachud in u negatiatad tgroamant dqted Mitch 21, 1973
ostdblishing a provisional overhead rate of 2&amp;5 for all
programs of this Association affective 7/1/72.

In prior contract raiuburaamnntn during this parted.va
have raqnnuted overhead reimbursement at 205. Total Garnet
coats ware $7,078.08. we have bean reiﬁburaed 1n the umaunt
of $1,»15.61. A calenlation at an; yum; indirect cast a!
$1,698.7h. The difference of $263.13 in a reimbursement
reqnnated in cur request autad April 16, 1973, to which this

letter is

uﬁtuched.

This change in ovurhaad rate will not interfere with the
porfbrmange of tho conﬁract Gr subcontract. It in our
undnrstanding that thia gantract may‘be extended for an
additional 6 montha. and under that extension we will request
nupplamentary funds to gravid: for the increase in overhead.
should such request fur ndditional fund: prove necessary.

sincerely yuurs.

i-nmxawaw

Mt: Fink, M.D.

Exscutive Director

XIII:
Enc.

�Avril 16. 1973
Contract

Ruforonce

Previauuly

Expenditure

Cialnnd

annulttivo

“N

11,537.00

This Period

?ﬁimﬂnuiiv

Tbtnl

Contraet

III

Dtipcnds

c—1

Supplies. Communications

C—E

Oak

III

Bul

3-3

B~5

B~6

Equipmsnt

1.h1h.73
13,359.50
h,721.00

Salaries

58.1‘31000

and Camputer

W
c~3

east:

11,537.00

lruvol

Lib. Analysis
Vbluntcar Faun
EEG

2,916.20
~m

h.soo.oo

12,83h.oo

1,690.00

Recording

h.330.93

13.359.50

h,721.oo

~‘h

58,h31.oo

a.“

12,83h.oo

on“

1‘

$2,916.20

Overboad (2h!)

622382

Additional overhead for period 7/1/72
2/23/73
Total

»

3,616.09
283.;g
$3,899.22

Eh: unaornigned certifies that tho cost at the acrvicos roiﬂburaablo
to thp Contractor and the Imount of the to: onrnod by the Contractor to
the ante of this certificate are not 13:: thin the total payments received

:3 claiaod by the Contrnctor (including tbs pcyment claimed herewith), and
tbs Contractor. to tbs hast of his kaoviedgc and belief, his eonpliod with
tho eanditions of the contract fully.
Ht further certify that tbs amount: inwaicod bargin do not exuaad
thy lovnr of the contrtet prica. or maximum levels esttblishnd in
accordance with Executive Order llﬁho or January 26, 19ﬂ!.

Intornaiional Association for
Psychiatric Research. Inc.

Fink. M.D.
Executive Director

By Mb:

9500.00

1,690.00

�W

January 25. 1973
6:01
The sixth annual wanting at the Boarﬂ of Directors
of the Association was held at 6 p.m. on Thursday evening. January
25, 1973 at the home of Mr. aha Hrs. Henry Faiwel, 7 W. 81 at. in
ﬂaw York City. All members of the Beard (unasrs. Canter, Fatwal,
Fink. Green. Israel, ?oge1) and a cannultant, Dnnsld M. Shapiro. 9.56.,
wore present.
6:02
The minutes
upgroved as airculated.
'

at the

mecting

at

Decembar 20. 1971 ware

The year's activitias ware reviewad by Dr. Fink.
6:03.10
noted that the studies or convulsive therayy were campleted. sun
had confirmnd that changing electrode location raduned comglicationa
of unwary less an&amp; yet sustainad tharapeaﬁic efficacy; and that
mmltigle seizures in ona sitting were safe, but of occasional
therapeutic advantage over single seitures (mﬁ 15561~03).
He

6:03.11

The conference on.Pchhnb£oZogy af‘Cbnvquivs Therapy
£0162) was held at the Dorado Beach Betal in Fumrto Rice in
April. Dr. Graen represented the Association ané reported on the
uaadaaic effort which wag austained for 3 ﬂaya despite the attraction:
or the beach and sunshine. The proceedings &amp;re new ccmplete and.w111
(RH

be published by v.3. Hinston ana sons in Eeptewber. 1973.

As one consquence-ot the mgating, song collaborativa
studies were stimulated. walier B. Easman, Ph.n3, M.D., ?ro£essor or
Faychology at Quesns College has submitted an application to KIMH for

6203.12

a study Ekurcohamical Changes
zuypozthog
RE 2 1 5

in Eiaatroaanuulaive shock

.

Qur sacond fauna of interest is the atudy or chronie
6:03.2
bathtub users in Athcns, Greece (stuh2.?o~98). Laat year we found
the population of users avgilable {hr stuﬁy ta have amoked hashiah for
an average or ah tours, and to aha? few madical handicaps beyond
cmphysama ana poor dantitian. We noted that tha subjects were hatwy
smokers of tabaoco and tha$ this preventaa any conclusion eoneerning
hashiih use alone. Because the man showed great tolerance tn canndbis
wt proposed this-year to test their response to v.5. mariauana. the
pure active aomponant (TﬁﬂwAn9). and tn high doses of hashish. Thane
studies in 20 subjects have been cangleted and the data is now in

analysis.

�“2*

6:03.30

the program
transferred

On

A

new

area of Aoaoeiation support

this year

in

was

and Ewan Payohophamoowgy (mahozo) , which wen
from the Kev York Modieel College to the Association
October 1, 1972.

6:03.31

EEG

feeilities at a

In the negotiations in the spring, renovation of

new site and transfer costs were found to require
about $22,000. we were assured of $16,500 to $18,000 by the notional
Institute of Mental Health, and requeoted the Association allow
expenditures of ita'funds up to $6,000 for these purposes. Dre Green
enquired whether the State university at Stony Brook would not
provide for these costs. While the university mey have dooe'eo,
it would not have been feasible before l9?3~7h, and would have
required tranafor of the NINE support and equipment to the university.
‘

03 32

expedite continuation or the program and to
of these studies, the Board approved
the allowance (to $6, 000) provided by the Executive Committee in
6:

To

J“13* 1972 o
6:03 us

The Association made two grants—in—aid

maintain e direct

AIME support

in

1971—72:

$1,717 to the Universitv of the West Indies, and $1,000 to the
York Mbdical College.

New

:u The west Indies grant provided interim support for
6:03whl
personnel in a study of ohronie ganja users. We had anticipated
HIKE support for these studies. Approval was given by KIMH but on
final review was withheld by the Department of State, which noted
that a prior contractor in Jamaica hed failed to abide by the
regulations regarding publication w their results were published by
the Minister of Health without prior 8.3. approval.

6:03.h2
The New York modioal College grant was in support
of legal assistance required by the Department of Psvchiatry in
negotiations with the City for continued roeearoh and teaching at
Metropolitan Hospital.
An extensive audit of the Aeoociotion'o records for
6:03.5
the period Juno 1, 1968 to May 31 197 by the comptroller, HEW
audit ogonoy, resulted in a lengthvreport (July 6,1972) (Audit
Control 300h6~02). most of the oriticism was focueoed on a look of
controls of expenditures, purchasing, and time records, these
being monitored by the Executive Director. many of the suggestions
for inoreased control were adopted, and on August 2h, we responded,
noting the changes which we had adopted. 0n Hoveeber 30,1972 we

wore advised that our response was satisfactory es to the management
eepeots; and on January 17, we were assured that the costs incurred.

were deceptod, without penalty.

�«r.

.~

._.

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,1,

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_—v,.

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m7

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~3—

6:03.60

With the transfur of tho grant EEG and Human
Pbyohophanmaoology, equipmont and programs with a replaonmont

valun of $130,000 were accepted by the Association. In discussing
the inaurdbility of the equipment, the question or title van raised,
and tho Executivn Dirootor was aakoa to nttompt n definition of the
present title, and legionl source or funds for payment or insurance
proniumn._ In the intorim, Mr. Cantor assured the Board that the
equipment was insured_for replnnqmnnt in case of major damage.

6:03;6l

by source.

site,

‘

6:03;?
with thanks.
'

6:0h

roqueuted an no~to~dnto inventory of nquipmnnt,
and estimated rnplnnemnnt coat._
.'

The Board

VThe

Board accepted
'

the Executive Director's rcport.
.

.

The 1971~72 annual finnnoial report, submitted by
Zimmerman was roviawod; and aceepted.

Panoth, Hobor and

6:05
The 1972n73 reonoat budget submitted by the Executive
Director was reviewed ana approvea.
6:06.1
The Board went into executifo session, as the Commitﬁoo
on Exporimnntnxion in Man, chaired by Dr. Martin Green, with Professor
D. M. Shapiro as special consultant.
The Committee revieweé the assurance of the study of hashish

users in Greece; noted that no additional studies of BOT ware donc
since July 1971; and reviewed the protocol and consent form for
studies of new drugs in the program, EEG and Human Phyohopharmaaalagy.
The Committee recommendod chanson in the consent form, and with the
assurance that those changes would ho acoeptod, approve&amp; this study

protocol.

6:06g2
The Board re~convened and accepted tho
Committee an Emparémnntation in Man.
6:07”

The Board re—elocted

its

report of the

newborn; elected Donald

Shaniro, D.8¢. as a new wombat; ﬁnd remelocted Max Fink, M.D. at
Executive Director for 1972u73. The Board elected T. J. Israel,
as President; and Mbrtin A. green, M.D. no secretarymtreannrer.
?anoth, Haber ana Zimmerman were named auditors for 1972—1973.

M.

Jr.

6:08
The Board gratefully acknowledged the
of Mr, and Mrs. Foiwnl for the annual wanting. In the hospitality
ensuing
disoussion, reprcsontation by woman on the Board was raised an a question,
and the Prcsidont ogreed to oonsidor snob nominations to the Board at
the next meeting‘
6:09

The meeting was adjourned

at 9.30 p.m.

�</text>
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                  <elementText elementTextId="106680">
                    <text>«WV.

.,.

“Var—.mwx.

—.v

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~-~

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._...7.—.w~,..—.,‘.w~wow—wuwmy‘n»

.

v

-

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-,.

--

,

‘—

‘-

73B:0900r

April 15, 1973
Dr. H. van Riezen
Scientific Development Group
N.V. Orgenon

088, Holland
Dear Hank,
IND

Dr.

the enclosed copies indicate, we have filed the
and the extension of the ﬂI-63 for Dr. Kaetin.
Kastin is free to begin the project; I have to wait at
for

As

GB—9h

least until

May

5.

The 01-63 experiments have continued until we have now
given 7 (x13.5 mg) ampules in 9cc in 2 minutes. Even at these
dosages, there is little to be seen in the visual EEG. We are
reviewing the computer outputs and the symptom reports. In the

are some suggestions of effects; and if these
are substantial and matched by the EEG, we will do a direct
comparison with placebo.

letter, there

ﬂ,“

v“...

,
_.,_._..,....._.,,

I have spoken to Dr. Esemen, who received some supplies
from you and will do the studies later this month. I have not
spoken to Joyce or Iver.

V'rw—

wuﬂwr

family.

My

best regards to all you! associates,

and to your

Sincerely yours,
Max

P.S.

The work
my

at Stony

Brook

Fink,

M.D.

is going very well. I should close

laboratories in the city at the

end

of June. Also,

found a small home on the water near Stony Brook, and
in the midst of the negotiations now.

we
we

have

are

�</text>
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                  <elementText elementTextId="106681">
                    <text>.,, ...v

V

5.

V

.

,

,,

.

..,..r., _w.,_._. v,.. ,7“. 7“...“

m.

,.

.

u

-—-,

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-...—n—.,...,.._v«-rw.7-

A.

73SB:09lSc

April 1h, 1973
Mr. Herman Heisman

Sr. Clinical Associate

Hoffmenn~Ls Roche, Inc.

Nutley,

ﬂew

Jersey

Dear Bank.

Following our discussions, I have revised the protocol
the ongoing study or the EEG profile of bromszepem (9 mg),
diszepem (10 mg) and placebo, with blood samples drawn for
fOr

assay of these substances and metabolites befbre and 30, 60
and 120 minutes after drug ingestion. A copy is enclosed for your
review and

files.

-

study began on Thursdny. In three sessions that we
encountered no difficulties beyond the discomfort of the
ran,
subjects at experiencing four withdrawals of blood. Should this
become a problem, we may have to increase the 'bonus' paid at
the end of each study.
The

we

my

best regards.
Sincerely yours,

Mex

Fink,

M.D.

�</text>
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                    <text>TSBBnSRl

April 13th, 1973
Mr. John R.

Coastline.

Karootie Investigator,
Suffolk County Health Dept.,
Hospital Affairs Division.

Route #113.

Riverlsigh Awa..

Riverhead, N.Y.

Dear Mr. Cossolino.

I am pleased to give you tho following summary of our
use of Schedule I drugs at the Health Sciences Cantor.

«pr-1

my”-

-‘—va.

rpm-rye:

F’s'"

m

war.

.

l. The principal study program is an evaluation of
narcotic antagonists and narcotic substitutes in the
treatment of opiate dependence. This study is in two parts
an experinentsl part at the university and a clinical part
at the Veterans Aﬂministration Ebspital in Horthport. This
study program is supported by a contract from the National
Institute of mental Health, HEM h2—72—llS (Antagonists to

—

Opiates).

In the olinicsl program at the V.A. Hospital in
Horthyort, we are treating veterans she have been using
opiates for two years or longer with oyolssooins. methadone,
lavomethadyl (l~alphs—acetylmsthsdol) and naltrexone. As
part of this program we also use heroin ehallenges.
During the next svo years we anticipate expanding the
substances to be tested to include diprenorphine
of
range
and 302605, as narcotio antagonists, and such other opiates
as may be of interest in order to define their duration of
action.

1n-

5W

“cw“mvm

arm“

V

Specifically, patients vith a two year history of opiate
use are examined and based on their psychological eharaoteristios.
recommended for maintenance or dooonditionins therayw. It
maintenance therapy. we follow the FDA guidelines for the
treatment with methadone. Approximately one half of the
subjects are maintained on lav dose methadone (upgrox. SO as)

�Mr. John R. 001501130

~2~

Agril 13th, 1973

and half an high dose (approx. 100 mg). During the ncxt
month a portion of tho patients who have been on methadone
ten months or longer will b: trtnsferrad to lawnmothndyl at 80
mg thren tinns a week. This, too. will fallow FDA

rusulationa.
Sam.

patients are inducted into deaonditioning thnrayy

in which they reeeive cynlnaoeine up to h mg a day (or
beginning July, naltruxona to 100 mg a day). At these
blockade

is

donagaa

measured by challenges with heroin or morphing.
usually 25 mg of auch.

In the experimnntal program ut thg university, um
are attampting to find the EEG and other phytiologie effects
of vurioun substances. unler this contract 9! are assessing
the EEG effects of naitroxona, morphing, diacetylnorphina.
etorphina, and extruetl o! cannabis. A yortion of this work
is supported hy MK 2&amp;020 "EEG in ﬂiman Psychopharmacology",'
a grant from the HIMH.
—

In this program suitable voluntecru are given
participating experiment: in the EEG labdratory and for
patina: of up to six hours have phyniolagieal recording
after adndnistration of one of the scheduled sﬁbstances.
substannos are dalivared, they are usually sent
office (at Stony Brook). Such supplies as may be
naceassry at the Vbterans Administrutian Hbspital are
trannshippea to the V.A. and maintainod in a safe similar to
that which we have at the university. (Pbr methadonn and
other aubstanaea usually available to thn V.A., we obtain
our supyliaa tram the yharmney which maintains the basic
anywlics and rcoorda,and delivers to us, in individual
bottlas, drugs for individual patient: fur specitiad days).

to

Khan

my

2. Fur a number or years at have been studying tbs
smoking cannabis, hanhinh. ind various derivatives.
such as TEC~delta~9, Tﬂc~deltn~8. cunnubiéiol and canndbinol
on physiological maasures such an EEG, heart rata,
respiratory rate, pupil 3130, ate. This wart was done in
New York under RIMS grants, &amp;na a eontract HEM h2—70~98.
This contract included a study of chronic hashish usara in
Greece. where um have 1159 examined the ﬁkysiological
attceta of that: antitancen in tents inhalation experiments.
This part of thn wart in Grace: is continuing and.v¢ have
reqnnstod funds to cantinue tho v.3. portion at tha
Uhiveraity.

effects of

�‘Mr.

John R. Ccaaclino

April 13th, 1973

~3~

In the laboratory vcrk, cuitcblc volunteer: inhale
these substances in thc KEG laboratory and remain under
supcrvinicn far periods up to eight hcurn. Physiological
rnccrdingc are than analysed.
3. Am the present tins cm are negotiating a contract
with thc V.A. for the ccmpcriacn of lunlphc~ccetylmcthadol
and high and low dose methadonc in the maintenance of
patients. This atuay, if it is fundcd, will he dcnc at the
V.A. in ﬁcrthport with cutpctiant units at still to be
dcsignated‘tizci‘in thc County, one or which will he at thc
\Hcalth Scicncea Center.

are not limited in our studies ,6 Schedule I
substances. but also access substances in Schedules II, III,
IV, and v. Fbr all these atudies, for such substances as
heroin, marihunna, THC, ccc.. supplies are obtained tram the
NINE. we have in the past, and plan in the future, to
obtain supplies of cannabis tram this source and transahip
We

these to the university of Athens under our contract
Bhiymcnt is to Professor Costa: Stcfanin.
at tbs University of Athens (Th, Vasilliasis Sophia: Ave.,

H83 h2—70a98.

Athens. Greece).

Occusianally

we

deal with substances which are sent

to us by laboratories in Europe or the U.S. In the past,
this has been true for hachish, etcrphine. and diprencrphine.
As our studies continue, we anticipate immorting such othcr
substances as may be necessary fcr our studies, and which
may be similar to the one: already atudicd.
5.7-

-(n'

a»:

a"...

This stctcmcnt is submitted in support of our
application for a licence to engage in research with
controlled substances. I trust this infbrmation is useful.
Thank ycu

fbr your acsistance.
Sincerely yours,

max

rink.

M.D.

Professor of Psychiatry
MF/ij

«1—sz

.

’

�</text>
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                    <text>-.V«—~ﬁ.v~-WMW-‘w~"wwl—-‘Wﬂilr

:w‘

.7.“

,.,,,,_, -;.---v

"mu-«mmvw

~-.m 'I.'ﬁw§&lt;rrv ‘

un-

“WV-v.”.vn‘nww-mw-r-

7383—619

Amen

12th,

1973

Dr. Robert Bobimon,

A. II.

Remus,

Mass Drive,
Mahmud. Va. 23220.1507

Dm Dactor Rebinsoa.
we the curricula. vita at Dru. Robert
Swanson. pad :43 updated. unionism
for melt. I ‘hmﬁ than are main]...

Enclosed

a

Dana tad Donia

vita

Sincerely yours.
mrmmmwmv'mvwmm

F1“. “09.
m
Professor of E’mhiatry
.

ant/13

men.

�</text>
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                    <text>7:101

r.r-

[I'm-ran

T3SB~618

April 12th. 1913
Alan Bunny.

91.13.

,

Modicnl Consultant.
Clinic-.1 Drug Studies

Center for Studies of

Rational Institute
5600

timers um.

Rockdllc,

at

Section.

and Drug Abuse,
WileHaiti),
mm

Maryland 20852.
gag

ﬁlm-124;:

Dar Doctor Runny.
Enclosed

is the quarterly report

tin Joint {annuity-VA

due Max-ah 31w.

for

drug dependant» treatment facility.
We have been heartcned by the pram-en 1n the
acuity than
months and the hupm advice of visitors from
put few
in
local and national syncing. I trait this

hapm.

awry

Sincerely yours ,

ﬂak.
m
Profusor of

H.129.

159/13
Em: 0

thiutry

�STATE UNIVERSITY OF NEW YORK AT STONY BROOK

HEALTH SCIENCES CENTER
_

School of Medicine
Stony Brook, N. Y. 11790
Phone: 516-444-2413

Department of Psychiatry

w.

u*wu~—"

#7.,

,..,,.E...,.

Quart erlLRenor-t - 'DDTC

V-oam.

Department of Psychigizry,

§UNY

_ ,,____._

atiS’ico‘ny Brook»
_

and

Vétéfans AdminiStration Hospital, Northpdrt, N.Y.

January 1, 1973 to March 31, 1973

h Prepared

by

Max

Fink,,M.D.

_

-a-

V‘

- _..,. 7,-

�l.

Program
Admission of drug dependent patients to the inpatient unit

remains at 19 during the quarter; with an outpatient census increasing

fron.6 to

11

in

March.

Of

these patients, 19-21 have been sustained

on methadone and h on cyclazocine.
The

introduction of cyclazocine in

hesitation by the staff

and new

December was met by some

were inducted slowly.

patients

We

introduced heroin challenges in January, and defined blockade to
25 mg heroin at 2h hours in subjects at h.0 and h.5 mg cyclazocine.
Late in 1972

"

disorders of thought
opiate dependence.

we

that

became concerned

some

and mood which complicated

During the quarter,

these patients and found that

we

patients exhibited

the problem of

paid Special attention to

combined drug therapy was
necessary

in five inpatients receiving methadone,

who were

given antipsychotic (3)

and antidepressant (2) adjuvants.
The

rehabilitation

was improved with continued

efforts at

assisting the veteran_adjust to the problems of a declining industrial

activity in Suffolk
welfare programs.

County, and inadeouate local housing and social
We

introduced a model

home

living unit in which the

veterans are encouraged to solve the daily problems of self—maintenance
and home care.
From a

methadone

technical point of view,

tablets ("biscuits")

we

discontinued the use of

and introduced

liquid formulations of

methadone (and cyclazocine). Drugs are prepared by the pharmacy in

individual, patient-labelled, dated bottles.

�.2. Administration
The program was
Don

established in July, 1972, with Dr. Alexander

as the unit director. For personal reasons, he reduced his

attendance to two half sessions a week in September. Early in March,
Donald Swanson, M.B.B.Ch. was appointed as unit leader (see curriculum

vitae).
~w~rs¢~
—--—.~..

....w-———.—

‘

Institutional approval

Z-alpha—acetylmethadol

stabilized
we

we

was Obtained

(LAAM).

on methadone and who

plan to_transfer

DDTC

“”“M”

‘

"“'

'

,

them

have been

facility

LAAM

for the introductionmof_mw~‘~~

outpatients

who have
“a"-4..

been

-

attend the clinic three times
in lateﬂﬁpril.

'

'

M

a week,
'

””w”;

notified that the renovation contract of the

approved

3. Staffing of the

to

For

““““v-_*~”*

last

summer

willphe undertaken in

May.

DDTC

With the appointment of Dr. Swanson, the unit now

is served

by: Phisiciané’-”1T?WFTE;WNu£éé§“Z”6.7'FTE;“Nursing“Assiétaﬁ£"L~7.o
FTE;‘Recreational and Occupational Therapy - 5.3 FTE; Social Worker and Secretary

- 1. Consultant staffing is

h

half days each

week.

_"“”"‘”

l;

�E
E

-3—

b

For the period January 1

E

E

.
E

V

E -_

_

E

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7363-51!

April 10th, 1973
Crook,
Peychophermecology Reeeereh Braneh.

Mb. Thames

Rational Institute of ﬂeatel Eeelth,
5600

Fishers Lane.

Rockville, Mbrylena 20852.
Deer Hr. Crook.
Thank you for the infatuation regarding the progreee
of the grant epplicetion by Dr. Thomas Kenlon (MK 2&amp;323).
I have reed the revised program and believe it is
eeneietent with the recommendations or the eite visit team.
The present protocol does not require computer eqniynent
and in essentially en encasement of the visual eveluetion
or the EEG. This type 0: analysis is well within the
eulpetenee of the clinieel teen end ehould reqnire no
expenditures above those listed in the reviled budget.

Should

this program demonstrate merit. the cemputer
EEG

evelnetion of the
yeere henee.
With

studies eauld be anticipated

this in mind, I

ﬁbula be contributory.
Thank you

site visit.

do not

some

think another site visit

for the opyortunity to particiyete in this
sincerely yours.

me: Fink, M.D.
Profeesor 0! Psychiatry

mrlid

cc. to Dr. Doneld Klein

�</text>
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-—-r.'uLP,'wa-_,—

M

—nr

wwwpm

731:0856r

n

«

,-:.~

.11

April 10, 1973
Costss Stefanis,

M.D.

University of Athens School of Medicine

Athens, Greece
Deer Castes,

I had delayed paying the consultation requests as the
Association was over—extended in its advances, and the NIMH had
withheld payments until the accounts had been verified. I was
assured of payment today and on sending the enclosed as advances on
your requests.
We

have not yet heard from Washington.

The computer programs have been put on tape for you and
I have been told that there are documentation notes that will be
written for your staff. As soon so these are delivered, I will

send them on to you.

Dornbush and Volevks are continuing their analyses of the
and behavior date. Today, they assured me that these would
be complete by next week.
EEG

My

best regards.
Sincerely yours,
Mex

P.S.

Fink,

M.D.

still trying to get an export license. Last week I was
by the U.S. BNDD and told that my facility at Stony
Brook would have to be examined by New York State inspectors,
to assure the government that our facilities for the handling
of dsngerous drugs were 'secure'. We were examined on Thursday
and I hope that this means that a permit will soon be issued.

We

are

called

�</text>
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                    <text>7363-607

April 9th, 1973
Louis J. What, M.D.
Departnmnt of Psychiatry.
School at ﬂcdicina.
The Center for the Health.8ciences,
Lon Angalga, California 9002h.
Dear

Jolly,
I w0u16.be plea-ad to endorse your candidacy for

President or the

American

Psychiatrie Association.

I believe that the alection of A1 Freedman marked
a signitiaant change in thn ecurnc of the history of
the ABA. For the past daeadc I have antenna the ABA
attcriorate as tbs programs becwme too big, with
repetition of papers by the saw: people; the sections
were disbandod, so that man of common interact did not

have a nidua shout which to mact; the dues increased
exceasivaly with a heavy emphasis on building funds.
pension benefits, and ether monunaata for the central
office. I hurt also vutchnd the attcuyt by thc district
branches to aaaunn sans leadership, only to find that
thay are powurleas. and thnt provud a disapyointing
endeavor.

I

will unka heroic efforts to make tha
acciety
representative and to improvc its ability
to respond to the EﬂMUQrI- Perhaps, in your next letter,
you vuuld indictta such 183308 that you foal are important
to tha APA so that those vhn are inalinnd to sugport ynur
atndidncy will be ablo to docuannt their anyport with
stntcasntl shout the issues for the society.
know

my

that

more

Al

boat regards.
Exacercly yours.
Fink. M.D.
Professor of Psychiatry
Mb:

MF/id

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                    <text>TBBB~608

April 93h, 1973
To:

Dr. K. Boson

FROM:

Dr.

SUBJECT:

'Msthsdone, Alcohal sad Drivins' by
Barnard Newmsn and Arnold Dihrbsrg

MIX

Fink

This retort attempts an intsrssting svslustion of the
sffsets of tbs interaction or asthsdons and nicohol in s
driving sinnlstion task. The design nulls for three groups:
nethndons msintensnce patients, voluntser male students,
and

policeasn.

This rsport is grossly insnmplste an a nutter of
important issuss.
1. me ststsnsnt is made regarding the campsrdbility
of tbs three grants. not only as to nae, but, more
importsntly. the significant issues or driving exterisnns.
The authors do not indinsts whether the subascts vars first
given an optortunity to pwsatins in order to hnvs maximum
success bsfbrs the test, at vhethsr the tests wars dons
with an unsqnnl initisl starting position, based on
differences in sxpsrisncs.

2. The data is not analysed as to whether the chain
scares (errors per subasct ~ stlst B, C, D and E) reflect
signifinsnt differences using stsndsrd ststisticsl mstheds.
In the absence of the dsts regarding ths range sud
variability of the scores, na Judgsnsnt of the msin
differences tan be made.
Conclusions

In the (bushes of statistical processing.

this dsts can not to interpsstsd. (Perhaps ths willingness
of tbs authors to asks conninsions based on incnnpiste
analysis reflects their inexperisncs.) Perhaps the
Commission could ssh that the data bs analysed by a

stntistiasl consultant.

Hrlij

Eat.

�M

f ﬂ! “9‘?

�</text>
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                  <elementText elementTextId="106688">
                    <text>7333-611

April 9th. 1973
Henry

P.0.

Brill,

Box

22,

M.D..

West Brentvood, H.Y.11717.
Deer Kenry,
Thank you far the envy of the eeeond report of the
Conmiseien. and the eppendieee to the first report. I
have given one copy to Stan, and he thanks you.

I have reed this second report, and once egein wish
to commend you and the Commission for approenhing the
issues with a Judieioueness and evenhendedneee that is
so neeeseary in this time when drug use remains a under
political iseue. I, too, have been frightened by the
rapid development of e "drug ebuee a industrial - univerlity
complex". Rate that I heve added "university" he your
caution, for no time in the twenty yearn that I have been
in research have I seen so many departmental chainmen
Jung on the bend vegan of drug abuse in order to support
empires threatened by e rednetion in training grants.
The emphesis on elechel as a drug of primary

eoncern

of €38

is well placed.

A

few years ego when Earl Ubell

celled
as he wee preparing his series
to Z". he was eurpriseé whee I innieted that
alcohol was a much greater threat end problee.than heroin.
Indeed. when he cheated, he was thin to present e more
baleneoé pieture at drug nee.
"Druge.

wv Have
A

we

Finelxy, I paid special uttention to the Genuinelon'e
attitude to the hermetic antagonists. Althougﬂtthe
reeauaendetione are not these which I heve voiced during
the peat m ywe. I eeneur with the Commission (m. 323-32M
‘

as the beat eonclueien based on the available evidence.

�Brill,

Henry

14.1}.

~2—

April 9th, 1973

Oneo again, I mt to than}: you and the Commission
far having presented ache:- and Judiciaua rocmendationn whieh
I hope the Ana-1cm people will accept.
My

but portend rem“.
Sincerely yours,

I

Max Fink, Md).
Professor at Psychiatry
RIP/1.1

�</text>
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