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                    <text>July

30 , 1965

Dr. Emmi: Kelsey

Investigatioml Drug Bmoh

Division of

New

Food and Drug

Bmau of

mugs

Aminiamtim

Maine

Washington, D. C. 2629*:
Dear Dr. Relay:

labomtorios haw moantly become interested in the
investigation of the olinioal efficacy of cyoloaorim
in tho
Those

tmatmnt of the mentally ill. Cyclomrine (Sermyoin) is
ally available. However, mount mpomts (Vitek,
Pa *3;*~ . mu m r,
l: 203, 1965) suggests that this memo
may
Evutlc value in psychotic patients, especially
if
are two to thno timos the levels moommnded for
oom‘
'

We
mutant of tuberculosis.
;

the

Water 0.5 to 1.0ofm
daily
an
antiWsmﬁm
oonvulmt ammo (mm). m patients will be oboemd
in a cloud wand cutting, with m omtml and determination
of Samoa levels in sown: following
the description provided
It is our intention to
with or witlvut the oimdtmem

by

mad

Eli Lilly mo Sammy.

that of the oo-inwstigatom, Dr.

Simon,

an

enclosed.

At the suggestion

Tum-1 11:11 and Dr.

Jovm

of Dr. Ivan Bennett of the

Lilly Research
laboratories, we are writing to you for an IND umber.
Dr. Bennett
indicated that the monsoon! manufacturing and control infc‘mnatim
relative to this letter will be made available by his office.
mimic you

for your oo-ommtim.
Sinoomly youm ,
ﬂax Pink, H.D.

Profosaor of Psydliatzy

'

�</text>
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                    <text>July 30,

1965

Dr. Willim Karliner
1N9 Grand Cmoourse
Bronx 53, New York
Dear Bill:

It was

a pleasure to dust with you, and when you told an
how extensive your present practice was , I had a twinge of
mgmt for not having continued in the private practice of
Psychiatry. Hwever, the present opportunities are still
very exciting and I am writing to ask your permission for a
masher of my staff to visit with you in September during his
holidays .

Dr. Alexander Don is a graduate psychiatrist from South
Africa. who joined the staff last year. He is interested in
observing treatment nethods not available in this city, and
so inquired as to the possibility of observing Inddclon therapy
out. With your permission, he will call you
as you carry
and plum to be in New York during the
in
September
early
period September 1% to September 21 . Pampas he can come to
visit you at Gmcie Squam on Saturday, September 18, 1965.

it

My

I

would be

best regards.

grateful

if you would

show him

your techniques .

Sincerely yours ,
Pink, 1-1.1).
Professor of Psychiatry

Mex

MP:kp

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                    <text>July 30,

1965

Dr. Robert L. Kuhn

of
W1:
Itafiom lbspital
Hill
may.
m.
Bar

Psychiatry

‘

3

New

93:

York

Roads

Bob:

I an

no planned with

the

malts of tha Tridbspim

«mmmwmmofmmmm.
Imiladoutthisoldmwtmdlnwhaditmotypod.

paper, md

that

Would

ymmnditvithwlBBSmnaMmifitismmh
to submit in m of thc psychiatric 30min?

Idomthmifthinlatmrwillmhwuinmmrk
Wilcoxfm'dmvieitinguithywtrnmxtthnlmVe

orincmoam. IWyouwmahappymmmwpositim

mmumcmp.
My

but mm.

Sincerely yours.

Mijm

PM, NJ).
m
meeaaor of Psychiatry

�</text>
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                    <text>July 30,

Mr. Wm: P.

1965

Muller

Information Scientist
12, run do la Dole

Gama, Witurland
Bur Harm

Ihava madymr'pmgmso mport with ISIS aswallas the
of
list swat-d topics for futon martin. My associates and
I or: vary and: impmood with this mport and believe that you

Manolo job.
ham has taken a paydmologioal twist and and:
prom
plaond on the
is

am doing a
mo

mmum

Mia
maria:

primrily psymlogioal,
of abotmotors. '33 original intontim of gutting up a. ragimal
cantor hm Man disbandod mo in its stead, is a
project to more the ability of different classes of individuals
to abstract scientific doommnts in the specialized field of

P9?

‘6

Madcoisimhavabompainfultomforlbeliaveﬂmt

a documentation: cantor using the best traimd doomtalioto would
be an asset to our commity. Only after we have had axtensive
oxperienoe with a variety of abstraotom would I be than interested
in testing, periupa, the psychological
of those
that do the best job. However, tho Division Diraotor has
mfemd the responsibilities for this program to a clinical

Wadstios

that is that.
Pertmpo I will be in Switurlmd this fall, and if so, I would
hope that I could call you and perhaps mtum your kindness last
year and your patient: (hiring this carcinoma of letters.
psychologist,

mad

‘

‘

Koap up

the very find work.

My

best regards.

Simmly

youm ,

Fink, 11.1).
Professor of Psychiatry

Max
MFﬂcp

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                    <text>July

30 , 1955

Dr. B. D. Holland

Associate Dimctor
Abbott Laboratories, Scientific Divisions
Department 0! Clinical Research
North Chicago, Illinois 6006M
Dear Dr. Hollmd:
have recently reviewed our clinical drug evaluation
could introduce an
pmgmm, and it is possible that we send
would
us some of the
additional oanpomd. If you
both the compomds
on
clinical mterial which is available
would review this
and
I
under considsmtim, my associates
in mid-September.
visit
have
you
and pemaps we cm mange to
the summr vacation
but
be
delay,
I regret that them has to thisweekend.
period begins for two of us this
We

call you
I would like to be able towhich
material
you
the
read
having
after

to us.

when
may

I return and

mks available

,

Sincerely yours ,
Fink, Md).
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>July

Dr. Dean

J.

30 ,

1965

Clyde

University of Miami
P. 0. Box 8293
Coral Gables 1&amp;6 , Florida
Dear Dean:
The simple problems. I have received the enclosed inquiry
frat: Dr. Words regarding your correct title for the list of
omtributors to the forthcoming volmnc for Biological Psychiatry.
Would you please writs directly to its. Pbrford indicating the
identification you would like to have in that publication.

Earlier this week, (muck Hall visited me and we spent a
pleasant but puzzling day. He mviowcd some of the Hillside
mterial, and is pmscnting an interesting report to the

I could
of our
data so that he could continue his explorations of the effects

American Psychological Association . Neither Don nor
be sure mat he wmted exempt that he asked for some

of drugs

on EEG.

I am always plcascd to have people work on our data and
so have agreed to send him the material of the SKF study,a
copy of the progress mport I believe I have already sent to
you. (If I have not, I will be glad to do so.)
What

is

going on?

Thom must be some occasion when
My

we

can

met. men?

best regards.
Sinosmly yours ,
Fink, M.D.
Professor of Psychiatry

Max

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                    <text>July

Dr. Henry

30 , 1965

Brill

Director
Pilgrim State Hospital
Box 22

West Buntwood, New York

WW:

It is with great pleasure that I accept your very kind
invitation to participate in the forﬂaming CINP mating as
for a synpoeitm nan Ncumphmcom. I have
writtentoDr.BmdlnymdasIhavemOpportmitytoboin
Mp. this fall, have mined to meet with him in London, if
possible, to formulate a program along the stimlating lines
suggested in ynmr guidelines.

WW

As I will be vmtiming in the Hmtms later on this
nmth, Ihope I cmhavemapporhmitytocallyoumdpomeps
visit with you as I travel thrmgh Long Island.
My

best pummel regards.
Sincerely yours ,
Hex

Fink,

Md).

-

Prefesser of Psychiatry

HFﬂnp
ens:

MA-.._.,..-v..«.

..

.
..

a.

.
”1‘

an...»

,7-

_,_._

7n...”

..
—

Dr. Jonathan

0‘.

Cole

�</text>
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                    <text>July

30 ,

1965

Prof. P. Bradley

The Medical Seiwol

Bimianmn

England

15

Dear Dr. Bradley:

It is a pleasure to accept the invitation of the Program
Committee of the GIMP to participate in the plmning of a
symposium on Neurophemooloy. I lodt forward with keen
anticipation working with you‘ Following the Committee '8
suggestion, I am taking thin opporﬁmity to open our
diemzseims with the following tentative suggestions.

mating on the general subject of EEG md psychoplume-logy review ohms induced by psydzotmpic drugs in
psychotic subjects, whacking differences between schizophrenic
Varicmo

and depressive subjects and portraying drug specific pettems
1961); a general overview of EEG md behavior (Yale,
1953); nottodolow of oonputer techniqms‘ (Washington, 196%);
and drug effects in depmosive disorder-s (1965) . These
presentations were primarily focmsed on human observations .
In the recent Society of Biological Psychiatry meting mime).
and lumen EEG data were brought together on the special subject

(mm,

of "Nztioholimrgio Heliucinogens." Participants in this

sympoeimn included [no Abood, Richard White, Mam 11:11, and
w. P. Wilson. '11:: discussion and presentations were quite god
and beam of time limitations barely presented the raw material
of which “men was a omeidemble anomt. (If you wish, I om
send you draft copies of those muscripte.) As the subject
was of peat interest, perhaps a similar subject can be considered
in brain
for the CINP. The problem of cholimrgic
Emotion is of mtual interest, and such a subject would permit
dismeime of antidmlimrgic dmge including hellucinogens ,

Waco

mti-peﬂdmm agents ,

mohmiem in

amine and ooopolemine,ofoholinergic
various

201', and tho
psychotropic (Inge .

dxolimrgic aspects

A
one of focus is the peremxiel problem of the
dissociation of EEG and beluvior. Related to this subject is
the pmgmetic value of EEG. data for tho therapeutic efficacy
of peydwtropio (Mags; EEG dmngos in mimic as e pmdictim
of the effects in m; and in. men, the prediction of the general
effects of drug and the specific prediction in individual subjects.

�Prof. Bradley

July 30,

~2~

1965

of those suggestions provide a focus for us?
I am planning to attend the International EEG Metings in
View early in September. Peﬂmps we can meet in Imam to
discuss the program? My present plans are to leave Nan York
on Saturday, August 28, and I can be in London on Sunday aftemom,
August 29. Ifmoouldmgetomt,wocanspendafcwhm
planning the pmgm md this might be easier than an exchange of
Do any

letters.

the

As to other matters, I m enclosing a check for my (has
GIN? for 1-965 . Incichntally, scan mnths ago I received

for

the
galley proofs of one pmsentatim from the 19614 matings, but not
the other (EEG Patterns with Ocmbimd Drug Treatments in Psychotic

Patisnts; Drug Induced Dissolutim of Cortical Electrical Activity;
Imstigatims in Therapy Resistant Sdzizophmnic
Patimts) . May I ﬁnuim as to the status of these muscripts?
and

Wutic
I

loio'k

forward to working with you in this swims next
that we may be ablc to met in [snow mm: mm.

year, and hope
Hy

best mgaxdo .
Sincerely yours ,
Fink, Md).
Professor of Psychiatry
Max

2417'sz

cc: Dr. Brill
Dr. Cole

�</text>
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                    <text>1,1.“

mun”...

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-

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'VF'W-PW'

..

um"-

mwawm-

-

WWW—n ”er... w.w—-.—_.—

r“. ‘Kwtvww’Ir-wn—‘TM-VV um.

July 29,

1965

m.
'1‘an
P. 0.
61m}: Stunt station
m.
Box 2292

Now

New

York 1000a

mum:

of
umber: 634297-01, mt-03.
1mm
m

Mound in a crack in tho

~02,

$727.15

marina

311ml): yum.

that Fink,

fojm

H.131.

Bnmutiw Dimtor

».»,Hr,

“www.”

'7,

a". mu"...

.,

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,_ m V'-

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�</text>
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                    <text>W—wv‘v

:v ~4r&gt;-1'

--_-rr

_,

omzﬂ»

.-'1-vra‘--‘V..J4

.

~Wﬂ"m"’rmr—ww‘vx-wﬁ.m'l‘

July

‘

.7

—--

.

29 , 1965

Mr. Dick Buss
IBM

3800

Linden Blvd.

St. Louis, Hissomri

63108

Dear Dido

just mad an article which refers to a mual
distributed by 18H, called "mam: Hmdbook for pruter
Applications in Bioloy and Hadicim" which was prepared by
'1‘. Sterling and S. Pollack. The note indicates that this

I

mud
mu

have

was pmpamd

mtly
Do

mder M153 Health support and

being distributed by

you 1mm anything abom:

IBM.

this? If

mymprwideaoopyformtom?

mm.

it is

it is

available

Sincerely yours ,
Max

Fink,

M.D.

Professor of Paydaiatry

MFﬂcp

�</text>
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                    <text>July

28 , 1965

John A. Stem, Ph.D.

Departmnt of Psydliatry
Malcolm Bliss Mental Health Center
luzo Gmttan
St. Louis, Missom'i 631014
.

Dear John:

SKI? study.
on our ambarbital «
for your my momentstake
this opportunity to reply
You am quite correct, and I will
sons for the end of our
to some of tho questions new; and reserve

Thanks

present study .

effects is no
literature review of mbarbital
and chronic administratim is
problem, for the EEG data on some my bibliography (196%) and
detailed and quite good (e.g., see analysis literature is sparse,
zero cmss
12—13
Bmisr's (1952)) . The
availability of the tecmisnebyfor
the
however, and despite
this
I know of no good analysis of My drug effect

(l)

A

years,
mthod.

placebo with drug effects
"my were the analyses comparingand
in our critique suggest
also,
so batten” .7" We are puzzledsapling
problems and the small,
our lack of control of sleep,
are very 104
. Of course. our dosages
naimogemous , sample focus
of the present study. Daspitenolow
the
also, and this is we
drug effects. This
can
dosage, I believe
of 100 mg armbarbital IV in
problem to demonstrate the effectdiscriminate
the same dose
minutes. It is a problem to
2:31

waste

1y.

(2)

N

artsfact; or,

it

8

20,

d.f.

=

18.

Our

error.

regaining variables
(3) The shifts in the patterns of the Apparently,
analysis is a problem. with some condiin discriminant fmctim
change
show
greater degrees ofand
diffcmnt momma
be a statistical
sample
tions. This may reflect our small
Further
differences.
drug effect

studies

may

must be done

mpmsent

to answer this criticism.

�(u) Incidentally, the direction of drug chamgcs are
indicated in Appendices 2 and 3 by the signs . For example, in
Appendix II, baseline cross average at 60‘ was much higher
(increased beta activity) for 300 mg than 50 or 100 mg. 02.67“,
1.3., 4 is greater than 2). Similarly, 50 mg (2) shoved a slower
Wane cross them placebo (al.96) but not significantly so.
(5)

Your commnt about

the Drohocki integrator and

is technically correct, but in
operation the curves are different. Drohocki uses a wide band"frequency analyzer" output

W

filter denying

that any information resides in
Our data suggests that frequency is a:
important aspect of EEG signals, and while power spectral
frequency analysers can be tuned to narrow bands, and thereby show
shifts in frequencies - these data are oonfomded by amplitude
chmgss. ms merit
any - of period malysis is that
mflacts frequency information independent of amplitude .

wicfth

shifts in fmquancy.

~—

(6)

A

hope

if

it

or a prediction

~

note the word "potentially."

The reminder of your consents are equally cogent, and I will
incorporate them in the naxt draft. I am grateful for your time
and consideration in mviwing this progress report. We are
replicating the study, correcting as many of the flaws in the
first study as we cm.
George has mantimsd your consideration of another laboratory
in Cincinnati. I hope the Opportmity will met your expectations .

that I have been puzzled, and somwhat chagrinsd
that the Opportunities in this center did not stimulate your
interest . Our political problem were gmat, and perhaps may
still be overwhelming - but I am confident that George would

You must know

be most enthusiastic
you wish.

to

have. you

Have a pleasant sunmer, and
our progress report.

join

Missouri.

many thanks

University,

if

for your review of

Sincsm 1y yours ,
Fink, M.D.
Professor of Psychiatry

Max

Hfzkp

P.S. While this report is not mady for publication, I am submitting
as an abstract to Neil for the next SPR meeting. Perhaps the
it
Program Colmnittea would like to include such a report of an
applicatim as a follm~up of last year's methodology papers .

�</text>
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                    <text>r... erw wwwn.

_

M,

July

’23, 1965

Centre; Accomting Office

Retinal Institute of rental Health
United States Public: Health Service
Bethesda. Maryland 2001‘!
I

.

RE:
Gmtlemzme Psydxietric Ree-arch Femdmim of

kiwi-8338431

’

Kim M
mkteddlﬁuexpmimmmietmininggrmtmim
terminatedJm 30, 196“. This meme ferﬁnsmof
832,000.00 for
and $8u0.00

nests

treinim stipends
at 29.
direct cementum were

Wed

The

sunrise;

for irdirect

$31,999. 92

for pretender“).

seamen for indirect costs and an item of $993.29,

(WI)
forﬁnﬂueerecipiente. Imefweetmthmmnmm

mien represents payments for social «entity benefits

appointedeulyl,wewexemquimdmpey0ASI
md again in 1965.

111195“

Immitimetthietimteimuireifmypmdtm

Muwmfmimmbemimdform
'emndumehmmympnmmmpmtewhidx

m

bedckeeping

enqumditm cm 111-8338 wmld he imimifiemt,
He amid be
for yew mietmoe.
Sincerely

yam,

Hex Pint, PM).
Emcetiw Director

on:

’

We

Dr.

Vm
mum

�</text>
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                    <text>“w.“ $1“qu w.»

‘w

put": ,., “—TTV.V-.W.-‘,,~-IM.....E rm.-&gt;Tlm'~m'n:m’ my.-

"Runway-w

.

v

ivy-vawur

July 28,

Mr. William R. Basoan

Messrs. Bryan, Cave, McPheetem
1630 Boatmn's Bank Building

8

—n-'w;v:‘nr‘—,“‘I'

»v.mL—u—w—r.«._~v; :

u -.m-

‘-

m.“w¢«~vu—v~uyr-.~.~vm-

1965

McRoberts

St. Louis, Missouri

Dear Bill:

maimed is the Certified Statemt of the Foundation’s
Accounts as of June 30,1965. It has been a good year
firmncially and the Fomdatim' 3 cash balance is slightly
more than $30,000.
The bank balance is approximately $9,000 with the
remainder of the Pomdation's fmds in U. 8. Treasury
Bills maturing at various times between October 7, 1965
and Jmuary 20, 1966.
My

best regards for a pleasant

summer.

Sinoemly yours ,
Pink ’ M. D
Executive Director

Max

mm

.

1‘

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0

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            <name>Creator</name>
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              <elementText elementTextId="18728">
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            <elementTextContainer>
              <elementText elementTextId="18732">
                <text>&lt;a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank"&gt;IN COPYRIGHT - EDUCATIONAL USE PERMITTED&lt;/a&gt;</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="18733">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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            <name>Language</name>
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                  <elementText elementTextId="104807">
                    <text>wwwmr

mm’m,

i," -... wv.‘w

-w~‘—'

.-

“3,——

July 27,

.. m,

m. pawn—m va-Irv- H

n'r'm w—'.\.v.-Vi-u."ry~mw"nu

1965

mu 5.8mm
Pairm
[Adm 2:, Missouri

Hr.
22

Dar-law:

Inphuodtowrdymmismpyofﬂmﬂnmcial

W!orthoyowcndnddm30,1965. Itnubee‘na

modm!inuzcia11y,mdttufomdatim'scashbalm¢e
i3830,309.90uofd‘m030. Input, maul-1mm
not uncut muxding ans-n for oquimnt which an

stillbiingpromm.

Mailing that we had no wtstmﬁngbills which
Ihave

mld’muinpmtmﬁnmtmmm,
mmtcdﬂutﬂnmhinﬁumtmnkbondtmd

W

by $20,000. md we 1m.
Treasury Bills, due
Jmunry 20. 1968 for a potential out: incum- of $389.00.
Tho

Tummy Bill- whiah natured‘m July 8,

won.

ninvcsted.

himsutumtsmthatmmofinm
ﬁring the past yaw equals $23,h96. This
our OW
to tho Fomdatim despite heavy

mt
for sunrise
m

«ad

for oquipmnt.

«militants

I'll-mu md Iii-83“ mid) m tbs training
mt:
gnmt‘smdmm 30. WofaihdmoalmlatotMpmpor
17..

social security bandits on Hie-8388 and as a comaqunnm we
deficit in that meant of almost $1,000. I am
writing to the U. 8.1“!ch Health Servico to inquire maths?

have a

mmhmmisammbymmmbemcapmd,
rmﬂutmisgzmtisnolmgnractivo.
mmtplgowimumatwedidaxp-ndinm

grmts $98, nos. 00,

leavingde balms: of $50,271.00.

miauuxpmdcdbalmmiatobomtmmdtotmmucmalth
Santia- after they haw carried out the necessary

waiting.

.

�“1-4-1

Hr. Stuart

~2-

July 27,

1965

Iwillbogoingﬁastduringthemzthofmgmt for

more are no inmletod matters before the
Pomdatim, ad I anticipate no problem arising which
my mquim spcdal handling during this period.
my

holidays.

Sinoenly yours,
Max

Pink, NJ).

Emmtiva Director
Hf'zkp

mclooun

wry—u... w...

,

�</text>
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              <elementText elementTextId="18720">
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            <elementTextContainer>
              <elementText elementTextId="18722">
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="18723">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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            <name>Language</name>
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            <name>Format</name>
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              <elementText elementTextId="82635">
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                    <text>my

-

-

r u. ~—-.r—‘ ‘v‘er ulc..~wﬂ'('

.

".an 3135' x Hrr'

.-. "yuan-mu

;

.

mwwn-w—wr-,

’1‘!-

”WW. «mwwq;~uup a-mvarmpwﬂ,’m.

vw"-—vm;v-n-&lt;vumw.

.

July 27,

NV".

1965

newWt

Mr. .C.

J.

Pinmoial

Assistant
Wm, Special
Bmoh

of Health, Education, and Welfare
Bethesda, Meryllad 2001'4
Deer
‘

MI“.

W:
is

Enclosed

e

copy

of the certified Pitmoie1 Statement

oftheWoWPmadatimofﬂiseo‘miforﬂm
fieoelyeermdingdm 30, 1965. We are submitting this

W

etnmttopmvichamie forﬂaeesteblithofa

provisional indium: oust rote for this ﬂea-1 period.
of the Menu of the
Pollock»; the

WWA-n,
WWWmﬂuimo-eetetmtfortmsmer
itieminumtatimtluten

lﬂsmmhummmitm

mane”,
eminent (812,230.00). ad a portion of the misal«apt
leneoue «(p-auditor“ ($650.00) mm:
entertairmt.
represents

forthe
wemdeomoleerutomproperenooetim
072%
08511. Both

and
mt:
Mum-mumhtedmdﬂuemmitmemdedthe

mod-bun“! expenditure:

on

direct ooet ended in the

mpted time expenditures

Pandetim
wtproper$821.00.
direct costs for which
on

by

The

“inborn-aunt wouldnot be mounted.
It 1e our opinion that the allowable indirect costs
applicable for the detemhutim of our indirect cost me

is

929, 200.00.

wring this worth: direct oxpmditums of research

to 31-07072, 07332, 08378, 08517 md’08597 equals
96,309.00. “me Pomdﬁim also ministered two training
gram, rib-mu and 111-8388 which carried special overhead
vellwanoes of 8‘ no 2‘ respectively. We two allowances
were negotiated and the emenditma under these training

mmbmtpmperlybeminﬂudetemimtionofﬂm
direct costs of the Fomdetion

purposes.
newcosts
an fully
mom

for

this basis, we helium the direct
stated in the sum $96,“09. 00.

Cm

‘

:m.wy..,._mp.xiv—Wm

�,,,,,

HP.

Stmttcn

July 27,

-2'«-

1965

On the basis of them data, we believe that the pmpor
for this fiscal yup using the 3am
overhaul Almanac
calmlatiam npplioable to pmiom yams, would be about: 30%.

m

Ithatthatﬁziainfomtimwillbehnlpfulinming

your. determinations.

Sincnmly yams ,
Max

Pink,

14.13.

WW0 Dimetor

�</text>
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    <itemType itemTypeId="1">
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          <element elementId="50">
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            <elementTextContainer>
              <elementText elementTextId="18712">
                <text>&lt;a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank"&gt;IN COPYRIGHT - EDUCATIONAL USE PERMITTED&lt;/a&gt;</text>
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              <elementText elementTextId="18713">
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                <elementTextContainer>
                  <elementText elementTextId="104805">
                    <text>July 27,

1965

thmm

Dr. Neil Burch
Baylor
1200

of Payohim

mivcmity College of Madioine

Avenue
Houatm, Tax» 17025

Dear Neil:
Enclosed on two abstmctsrfm those Movies which
mﬂeot mount work. for the consideration of the program
omnittu for tho £0111an meeting of the Society for
Psydmophysiologioal Pom. If oither, or both these
pmscntatim interest the ommittaa, Don and I would be
pleased to pmpam tho pmmtatiom.
Incidentally. we am still intamted in m analog analyzer
systcm and ottnr than a phom call fromymr engineering friends,
two have moaivad no follow-up visit, even though they sent a
latter stating that om of the engirmm would call no last

Mk.

My

best regards.
Sincerely yours ,
Ha):

Fink,

PM).

Professor of Psychiatry

enclosures

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                    <text>5

av rmtnrn—m-uvo-wv

an

—...«

wwwwnw.mm~..aw

WW"!

“mi.

“Hun-w“

Wimmv'ﬁv‘

n

r” 'H-l—t'au“*~

w

w

or...

July 26,

:-.

m

v

:

I'm'nru—s

.

.

n.

,wwc. *I‘Mra.~rlvhvw”' , "an

1955

Rickard P. White, Ph.D.

Asmiam Professor of W103):
t of
University of Terms.»

Mom!

Whit, Tmm

38103

Dear Dick:
om

I an aunt mteful for your mful .mviow of the report
cmnxm‘gm melamine in induced omvulsims. row- commute
rulpful and the cited
«mated my review.

Mama
m
You
that this data indicates «pilepay to have a
mat
and
diffmt bloom substrate man induoud oonwlaionshowever,
manta ismtaoolaar.

m,md1uouldm.

mdfm‘thar atudywinbemododtoclearupthispoint. Formy
I ma non intemsted in the data that law] hates
amtylcknlm in all that: moses. and in tholr similarities
than ﬂair diffomoua. The minnows to Aim and aims is
only partly true. Trypam red experiments, in seizms and in
therapeutic failms md soon interest ma.
mummies,

mm.

m

Inmaarlyamdyinmymsmamywemnistamdu‘ypmmdto

a

cabinets. with‘mt any clinmal effects
W of mmlogionl
mat startling akin colors”.

(«swept the

I

W

and
mat interested in your reference to
m
which
yet another momma Mby elevated

mm,
met: an affect cellular activity and
CS? and than mtylclnlhn
heavier. I didn't

know

their work.

At one tin I oolleotad the data mlating to other
macro]. amines and indumd convulsions. Tm data is spams
and not convincing. I eluted. tMmfom. to focus on
clalimgic ”denim, as those mvide a mm reasonable View

of tho

pm”.

Pamtlntionlly. I wt to canyon-Into you on your latest
article in tho EEG Jamal. It is an amount plane of mark, and
mils the armors m not as siwle an we would like the mmus

to be. the data and figures we conﬁrming. It is this
olamct ”idem. that the CNS «evoked mapcnae follows diffcmnt
pramoologioal laws than spontaneous cortical activity.
system

n4»

.n,

�,

v.74._ .._... WW-

-- ._ w...“ .W..._v.....,_v_..,..,......w.r
W--‘ 7V7_-'_7 —..,w.__... w "w."

_» _

u.

, .

aw.

~,....v,r

-‘ww..».,.~w,w

‘...-..,a-v....~mm“

1

..~

1'». White

July 26,

~2~

1965

Inmymdinglmntlylommsstmmmmiesof
W103};
Wuhan,tﬁt .,
mums

Cmr'tis and Boole: (a.
of Ctnlimrgic ma Admmrgic
ed K0: 1:, G. B. at 9;, Willa}, 1965) which
different «115' and call
can bu
clearly show
stimlatod or inhibited by mtylcholm. and that this: differemea
and evoked responses.
may ho basic to than differences in

less elegant, and m
”was am:5me
new
simultaneous
stimlimd
utudyof
ravemmntlymnﬁmdona
(0w am

“and

much

the evoked resumes.)

-

kindness in mvinwing
m
Immmmxgotomttogetmthis fall.
Again

my thanks for

Sincerely

report.

ms,

Fink, Md).
Profem of Psychiatry
Max

thm

my

Wm .n-zw

:

yu- ..

Iq'n-zw-a—rrl

�WAX

PINK,

NJ).

graduate of the New York University College of Medicine
in 19%, Dr. Fink obtained extensive clinical training in
mumloéy and psychiatry from 19% to 1952. After qualifying
as a osrtified specialist in both disiplines, he accepted the
position of Director of Ream in the Department of Expemmntal
Psychiatry at the Hillsios Hospital in New York.
A

In that position, for ten years, he developed an extended
research prom studying the neurophysiologicsl, psychological,
social and clinical effects of the various somatic treatments
in psychiatry.

-

In 1962 he was invited by the Govemr of Missouri to
establish tho Baseamh and Raining Center at the Missouri
Imtituto of Psyohiatry, a part of the Divisim of rental
Diseases of tin Stats of Missouri Cmmrmntly, he was
appointed Rascarch Professor of Psychiatry

Univsrsity

at

Washingtm

after attending the first Cowuter conference
on EEG hhthods at U. C. L.A., he was stimulated to study the
applications of digital waters to the field of specialisa~
In 1960,

tion,

EEG

and Psychophatmooloy

When

the opportmity to

oevslop the Missouri Institute of Psychiatry was given him,

kseamh Unit specifically
in psydaiatdo mam. ms present mater unit at the
Missouri Institute of Psychiatry is the wtgzwth of those

ha created a Digital Computer

designed to satisfy the special studies whim seamed isportmt

terssts.

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                    <text>July 26,

1965

Dr. H. B. Stainbedc, NJ).

m1 Advanced System Develomnt Diviaim

2551 sums Boulavard
Yoﬂctown Heights, Nan York

Dear mu

saw:

I mt Apologia: for not having mm: a spacific outline
of our “sport to the IBM Radial
scrawled for
with the
Detour 23. This owmiwt on our part is

mm mm,
of

which

Swim meat!
I hop. will mt with yam- Wu.

Imalmplmadtecmlaaoshox‘t biomphienl skatchos
and mm, as well as man Wasted mpies of
Min: vitae.
If the «bum: am 1:09 sketchy,
mm‘m

Mr.

our

perhaps the mv.

will

ha

of

water

assistance.

Phase accept a] 51:010qu for this late: submission, and

our thanks

far your kind invitatim.

Sinmmly
Hm:

Fink,

yam,
PLD.

Professor of Psychiatry

Mfzkp

«talcum:

�</text>
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                    <text>July 22,

Mr. Clydn

J.

Liming], Editor

Secretary,
Win
3. Wm
U.

mm
”a

Dopartnnnt

1965

Win:
VA

of "admin. and Surgery
25,

D. C.

M W:
HoopicsofﬂuSixthWCmfcwmofm
ministration, held m 27, 28, md 29, 1961,
Mm
wand appnciarto waiving a copy.
am still available,
we

Simmly yams,
Fisk, M.D.
Professor of Psyduatry

Mam

�</text>
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1955

Fail mad Gummy
230 South Bushman

Elmr

Chm,

lb.

Garden-m

Muhuwhmamtmttmtoumnm
mlmlhtoftrnofﬂmmdmsofﬁuhyohhtric
Rawhfmﬁmofuim:
MP-

W. B.

W

Mr. Mold C. Hunk:
George A. 'Ulctt. 14.1).

Hr. H. Hadley (Brim
William R. Banana, Esq.
Edwin F. Gilda. 24.1).
Hr. 9310 F. Jomm
Mr.

Mr.

011% hamburg
Sam
Stein

MUi‘hm

“amidst:
vmmddmt
Emmy

Wrm:
Ember

Hut-bar

Mbor (Rasimcd

6/65)

Simonly yams,
Max

Mfzjm

Fink,

PM).

Emutivu Director

�</text>
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                    <text>July 21. was

Tbmnmymm:

hem
mm
mmmmmmmmmummdmm
in Wm rm
43W the
associates
of
of Peyaaiatry
Dr. Jean Sim joined the
timing June. Be is a graduate maiden, having received
his. degree ﬁrm the
Faculty of 3m!) Waiver-shy.
‘

Edinburgh Waivemity.‘

Biplane

813

_

and
Mm mention from
was “Gallant. They matured that he is a

mm
seams worker, moientiaue ma mm
-

and cue-weathers .

by bath

Sims his arrive}. how, I have {and

.

mm

affable.
in

-

his teachers

pleeamt,
time! and reliable. I have no Mitatim
him fer 11mm in the State of ﬂiesom'i.
him

Simmly

yours ,

Fink, PM).
Professor of Psymiatxy

Mm

Hftkp

�</text>
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                    <text>July 21,

1965

Potter
5. Sterling Gummy

Mr. Tom

7849 North lindbergh Blvd.

St. Louis.

Hismi

Doarﬁr. Patton

Hymociates mdlwwldliketogoalnaduiththeexdxmge
I'll—1300 tow a 7
313.300 with four additional moon}!
mpmm militia-a. m tmslatim of ow present family of

m1

of an

100, fmm mama mime to $19400
y
matibloismquimd,andasmaathedetailoofﬂuemmnga

up»,

&gt;

H

mmhted.mwillmkmtatmfarofthesetmstoyw
hbomtorics for we): tummion.

We

is a signed mquiaitim
masonry stop in this
of Missmri, which W is tedmioally tho
of the £34800 . Attmd is a purdwoe order oopy which
has just been submitted to tho University for their acceptance.
The Wmity will bear no mmmility for the additional
clauses new: in your lotto» of July 2, 1965. These additimal
chars” ($3,825) will be paid by the Psychiatric Round:
Pamdatim of Missouri. This omtmot mktimship of the
A

m

from the University

Pamdatim is contingent

«new.

As soon

upon

the unwmity'a

mm the

as tho University has signs! the requisition, I

shall omtact you again.

Sincerely yours ,
ﬂax Fink, NJ).

Professor of Psychiatry

8?sz
one.

�</text>
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                    <text>July

Gordan

21 , 1965

M.D., Phd.D.Sc.
Mamm,
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Nam Battlnford, Canada
Dear Dr.

143:3.sz
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make

mfmtsmmdlfindlwakymtojoinm,

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opportmitytowrktogother.

Simmly

yours ,

ﬂax Fink, H.D.

Professor- of Paydaiatry

�</text>
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                    <text>July 21,

Dr. Martin

Special

M.

1965

Katz, Chief

We: Unit

Poyolwmamoolog Service Center

National Institute of Mental Health
National Bank Bui

Batmm,

Maryland

200.1%

I m rut-timing the

of the

0‘ Payciu'amo
mmyoumm sokindtolend
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Hawaﬂmdﬁdsbodc, mdlmgmtoful forthe

ma.

copy

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Handbook

opportmitytohawbunablcmasscasmundofsmdies
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have bun
with various rating coal». As
you hm, Dr. 11:11 md Dr.
have provided
with a
paydaopathologioal Ming soak which we haw fomdushelpful
in numbing drug offsets in our chronic
Perhaps we will be able to mdortake the schizophmic patients .

MUMMimr

studies suggested in Lyerly’a

volm .

masonry validity

M ya: again for your assistmoa.
Sinoex‘aly youm,

m M, HOD.

Professor of Psychiatry
mxkp

�</text>
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                    <text>July 21,

Box 1113»?

elo

ANA

53$ Norm

1985

Wm

(Mam, Illinois

80610

Quantum
in the latent isms: of the 3M“
to
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mental
the
health
an ”plat of mumphyaioloay or
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meassor of Psychiatry

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enclosm

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                    <text>July

20 , 1965

Dr. Irene E . Hwkow
Research Psychologist
Psydxomamaoology Service Center
National Institute of Mental Health
Department of Health, Echmation, and Welfare
Bethesda, Maryland 2001!!

MD”.

W3

Mywverymohforsendingmaoopyofywmview
A Review" which I have

paper, "To. Effects of Dmgs on Speech:
read with a great deal of interest. I fomd the review complete
and the criticism cogent and helpful. I would agree with you
that the paucity of armies considering the effects of drugs on
speech is indeed startling, and I hope that the forthcoming
oonfenem will timlaee mm mm study.

tim, we have undertaken a study of the
Inthe
effoatsoflﬂbmthe‘l‘fkmdonﬂwmte ofspeeoh.
131) did
found
we
that
summer,
collected
last
data
preliminary
effect the m, but did not alter the rate of speech signifiomtly
the
At the present

schizophrenic patina Of interest, was
mic
which, in these patimts, was
of the
of
ohmge
direction

in our

TI'R

smaller than in their pro—dung oondition. '{mis was contrary
to our expectaticans and differed from the Hillside Hospital
As you sweet in your mviw, we are relating these

its.
differences to the differences in powlatims,

have enough subjects would

initial level

as well.

like to

examine

Speaking personally, two of your

am! when we

the iwortanoe of

criticism of our earlier

mpomzad in 1960 were
studies are quite comet .
that better omtmla,
would
imdiataly
preliminary and I
of drugs and
selections
individual
the
larger samples, md
we
are limiting
study,
dosage are mammary. Favour pmem:
LSD me! will
of
kilogrm
gamma
cm
per
our data to the effects
have a control group.
The

studies

me

especially interested in your consent on "The senses
and adaptive mdmnism" (page 13 pp). It is indeed surprising
that more stuck] in this direction has not been undertaken,
especially considering the great deal of hterest that psychoin theories
therapists have expressed during the past few years
Your
moments
of the mode of action of psydxompic drum.
regarding our studies are comet, but it is manhunt to note

I

was

�Dr. Weaken

-2-

July 20,

1965

little effort had gone into the sum of
mmmim by linguistic mums. 'me most fruitful
emdthoseam
mrkinthis meisnotinoludedinyourmview,
R.
Kuhn
that at that time
defensive

the studies of E.
19%

to

A. Weinstein and
L.
during the period
1958. ‘meir work finally culminated in a Volume "Denial

mm

of Illness" published in 1955 by C. C. “mamas. My studies,
with the oollabomtim of Dr. Kahn, .23er applied
their extensive eaqaerienoe and date to the electroshock population.
The analyses of the effects of
on the speech of
patients receiving electroshodt were mdertaken with the framework of a theory of the action of electmshodt. We were satisfied
if the damages follomd the predicted direction. However, your
reqmet for reliability of seems is proper, and interested readers
may be referred to the other articles by E. A. Weinstein for the
mlemntaxy date.

mum

e[his review has been very

itwithDr. Dontomnw.

we

will sendyou a copy.

As

helpful to

me, and

I will share

somesmmdetam codified,

Ihopettntyouroonfemnoewillgomll,mdlookfomard

to its proceeding with e greet duel of interest. Again. my
thanks for sharing in your excellent review. My best regards
to Dr. Cole and your my (Jo-workers.
Sincerely yours ,

PM,
w
Professor of Psychiatry
HOD.

�</text>
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                    <text>.

- ..... -qw.“

-.wr.—._._,m._._.~....,...__ ........-~—_. w.~..__.mmwmuw-W—v."

mm

'

ww&gt;W'—_-'wxmfiwmm wuwnrmmwx-wmmru

July 20,

1965

m.

Dr. Estelle
Librarian
Washingtan Mwmity Medical Center

St; Maia, Missowi

has:

no.

I

my

would be;

grataful if you would aut‘tmize Hm. Sheryl
assistant, to (mack out library material

until fwthwnotiee.
m new

Avmch,

in

Wm
my

Sinaemly yours,
Fink,
m
Research Proms-m of Psychiatry
54.13.

Mfskp

~

�</text>
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                    <text>.Ttﬂv 90, 1%.“

Dr. Donald F. Klein

Hillside Hospital

P. 0. Box 38
Glen Oaks, New York
Dear Don:
Enclosed

data as as

is

the

listing of the original Hillside Hospital

have on our

item is enclosed.

tapes.

The code sheet

identifying the

In addition, we almady have tapes which give us differences
between pm and post on each of these items, and different
scores
calculated from a
regression for all three treatments.

If there is

m

anything else

we

can do here, please

let

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

{1?sz
enclosures

no know.

�</text>
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                    <text>.

July 20,

1965

Dr. Alfred

M. Freedman
York lidicel college
5th Avenue at 106th Street
New York, Hm York 19029
New

DeerAl:

I do Inpeymrtr'iptommpe m esuooeesful one, despite
the treneetlmtio telephone oella which you rent have received
became of the homing problems in the Depertnent.

I an in the midst of completing a report on oholimrgio
in convulsive timepy end while reviewing the
literature, om eoroea the moloeed two articles which brought

mechanism

to

mind the usage of possibilities for studies in the drug
addiction populatim. Reno, e1: 111, reported that a single
dose of norphim inoreeeed oe‘ﬁbﬁl eoetyloholine in mtmeted
mimele, huthednoeffeotinohmniomorphinizedmimle. The
oholineetemee activity appeared to be the some in both sets of
animals. They concluded that eoetyloholine metabolism in brain
may be involved in the mediation of demlopment of toleranm to

morphine .

This observation is of special interest when joined to the
cursory Rueeien report by Denisenko who remanded central
oholinolytio agents for weakening the dew/element of tolera‘me

to mphine md its substitutes.
From our point of View, we know that cholinolytio agents
produce EEG deeynohronizetion. It is also probable. although
for from pmven, that drug addicts tend to develop highly
EEG patterns Ming the course of dependence
.
these
observetime warrant further study. it would be
If
advisable to replicate Dmieenko's report, with EEG omtrols.

eyndxmnized

Iwillbe

oouﬁngEest formyveoetiondm‘ingmguet and

will take the liberty of oelling your office after you have had
eohmoetoedjuettohewYork livinginAugust.
Hybest regards.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Hex

enclosure

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                    <text>w- ‘ --:--—m~

July 20,

1965

0mm]. Mounting Office

;

Retinal Imtitute of Mental Health

muted States Public Health Service
Bethesda, Marylmd

-

2001i;

Gentlmn:

RE:

m

MGR-01
ﬂ-l 8388—01

an herewith returning Treasury C136: No. 77,828,213“,
dated July 1“, 1985 made out to the Paymmtrlc Research
tandem, in the mum: of $12,000. This cheek represents
He

amhadvmminﬂuebovemmt,
mmqmstedmﬂarmm,
1965.
when this

was not received by June 22, we
Human
requested payment of $26,166 for the coupletim of both grunt
m—aaaa
MGR.

paid.
mt
maloaeddndtmpnmtamowrpaynmxtmdishmby
mtunnd for deposit in the
and

This

($26,166) was

U. S.

Maury.

Sincerely yours,
Mex

Pink,

Mauve

14.1).

Director

The

�</text>
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                    <text>. ,,‘.

July

19 , 1965

Publishers
Springer-Verlag

Wien

I

Mlkemastei 5
Vienna, Austria

Gentlem:

Manama,

like to pumhme a copy of Aota
Section 2, published in men and mooning the
papers presented at the International Synposim in Gama
in 1963 under the title "myaiOpamolog of the State of
Consciousness ."
We

would

Valium. 12,

If

such a

the price,

wn

volm is available, if

will issue a formal

you would give us

Mose order.

Thank you.

Sinoumly yours ,
Max

Fink,

M.D.

Emwtimnirwtor

Hfdcp

v

.«w

�</text>
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                    <text>July 16,

1965

Sheraton Hotel
San Juan,

Puerto Rico
Gentlemen:

Please reserve a. twin bedded room for arrival on
Sunday afternoon at 1:00 P.M., Daoember 12, departing

Thursday, December 16,
Max

Pink.
We

will

be

at 12:30 PM. for Dr. and

attending the

Annual

ACNP

Siﬁcerely

Mrs.

Meeting.

yam ,

Fink, M.D.
Professor of Psychiatry

Max

Hfﬁcp

�</text>
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mvww a....w...,-....z........‘..“,‘- v... F. ﬂy-rwwwwmummmr,,. .ng‘uwﬁ—«w-m. “WWW...

July

w-...,.,_.~.m.

w.

.“M...—.

wwmy. m.“v_-._._.,.,,.wn,,v.

15 , 1965

Pawnlogist
St. Louis 3m:- Hospital

Dr. K. Palmer,

Arsenal Strut
St. Louis, masouri 83139
SHGO

Bur Dr. Palmr:
I have just monivod a letter from Dr. Balm

indicating that ya: luv. continued to supply him with
in the
pituitary gland- which he has
nupm
continued
the
of his can. It is only through
eta-operation of work.“ like youmolf that this tum:I would
unt and munch program can bc successful.thank
you
like to take this opportmity to
and join ma mum in expressing cur appreciation

rm

m

far your continued efforts.

many

My mm.
Sincerely yams,
Mix

Pink,

M.D.

Manor of Psychiatry

Mmkp

cc:

Dr. Known:

,

.. m...”— 4

”N'v

—..

�</text>
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                    <text>July 18, 1965

NJ).
Wm,
Clinical Dimctor

Heinz E.

Verdun Protestant Hospital
6875 LaSallc Blvd.
Verdun, Quebec

Dear Heinz:

delighted to road of your symposia on adverse drug
reactions, for I have just written a. letter to [so Hamster
to wk his commute regarding a problem which we have recently
observed here. I am taking the liberty of sending you a copy
for your opinion as well. Is this phemmana of "water intoxica—
tion" or ”paydxogenic diabetes insipidus" described in your

I

was

promedings as an adverse mactim to psychotropic drugs?
The syndrouo us have obscmd appears related to the phenomena
of dmgdnduoad parkinsmism.
‘

I from that the Quebec Psychophanmoological Rescard'l
Association will continue its good work and look forward to
the synposia as they are produced.
My

best personal regards.
Sincerely

yam ,

Firdc, NJ).
Professor of PSychiatry

Mm:

Wm?

�</text>
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                    <text>July

16 , 1965

«an,

W'Fzspw‘rmvw.

'

gammy-qr

‘l'

a

.«mm

.

Dr. loo E. Hollistsr, M.D.
Associate Chief of Staff
Veterans Administration: Hospital
3801

Jmipero Sam Blvd.

Palo Alto,
4

'
A

vauyymu‘wua

“W75

KETW‘R-ﬂ'kwwsﬁ'

EM"!

Califmﬁs

9&amp;30'4

merino:
chronic sdmizophmnic: patients with
butmmine, we have recently noticed an unusual complication .
'Ihis patient has developed room‘mm: episodes of severe polydipsia
and polyuris which appear to be mlstsd to the developmnt of
other symptoms of parkinsonism. The ochninistmtion of pmoyclidins
seem to msliomte the parkinsm syndronn and to alter the polydipsia
and polym'ia.
In trusting one of

01m

your intsmst in adverse drug reactions, I thought I
this am with you, and ask your midmos in the
study of this phemna. An: you man: of this mactim with
Knowing

bmﬁtilf

'4,.TWWIWW‘Z"

..

‘~

mule! share

phemthiazims?

‘

We are madsrtaking another sm‘ndmsntal period with this boy,
will do the usual urinary and blood studies including momma
of osmlsrity, which our oomultmts may distinguish psychogenic

and

polydipsia from diabetes insipidus .

kind,
If you have any oitatims referring to pmbloss of this
you may wish
would be gmtsful for them as well as any

I
mots
toma‘kesboutthis case. I antakingtm libertyofsondingyou
a short om study and a graph of our meant observations, which
my be of intsmst.
My best regards.

Sinosmly yours ,
«r

~1x~zrrmwr“~'m:"

Was-r

rmzeur

ﬂax Fink, NJ).

Professor of Psychiatry

�</text>
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                    <text>‘mni‘..,...v-.-.-.—.w-..ﬂ-....._. ~.'V 1....-.“

«w

p&lt;

7‘-

July 16,

Dr. H. van Gogh

Ahmndwm Gogh

Antenna-Slater:

1965

NV

811mg 11

Amtcrdm, Hollmd
Dear I». van

60331:

Dr. Itil, on moss behalf the medation had
entemd an order for a 2-chame1 telemtry system,
has inquired as to the status of this aquipmmt.
Can you advise us as to the pmbabig dalivery date?
Thank you

for your

W‘tim.
Sincerely yours ,
Max

Fink,

14.1).

Ebecutive Director
Hfﬁcp

�</text>
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                    <text>July 15,

1955

Dr. Spencer M. Prue, Jr.
Section Head, Statistics Section
Smith Kline 8 hunch Laboratories
1500 Spring Garden Street
Philadelphia, Pennsylvania 19101

mm:

Following your suggestion,

We

manic-minted the actual

Values for the first analysis for em drug condition. he
results an enclosed in these thmc graphs . The observations
for these samples show some discrimination'between the drug
conditions, but again, the clarity which we hoped to achieve
by maintaining a constant state of consciousness is not better
manifest . However, you an: correct in suggesting that this
fom' of pmsantatim is less subject to criticism. In the
final mport, when the new analyses are muted, we will
adopt this graphic model.
I

look forward

to visiﬁzg with

you on August 10.

Sinceme yomn ,
Fink, M.D.
Professor of Psychiatry

Max

Mfzkp

mcloaum

�</text>
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                    <text>June 15, 1965

We

W

Dr. Joseph Zubin

New

York

722 West

New

York,

State Psydziatric Institute
168th Stmet
New

York

Dear Jon:

,3» RT

I was talking
week and he

to Jmathm Cole about mother problem earlier.
mum your project on diagnosis. In this
naming mail I received notificatim from I». Grim that the
enclosed report has been accepted for publicatim. I an taking
unlibar-tyaf an; ywaoopybamlbeliem matthis
willmpportmyﬂ‘thatyom‘auﬂymcmmwpmiding
on mathods for the mum in.
objective aims
this

'

My

best regards.
Sincerely yours,
Pink, H.D.
m
Profesaor of Psychiatry

3k?

enclosure

�</text>
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                    <text>July 1a,

1965

Dr. Jormthan 0. Cole

National Bank Building
6917 Arlington Road
Bethesda, Marylmd
Dear Jonathan:

Haw received the GIMP Bulletin No. 1. I am delighted
with the program outlined. I mean your telephone call of a
few weeks ago and would be pleased to help plan one of the
sessions but do not know if I am autlnrized to proceed and, if

so,

how. Please
My

advise.

-

best regards.
Sincere 1y yours ,
Fink, NJ).
Professor of Psychiatry

Max

M'mp

P.S.

for your oo—opemtim in the ECDEU application .
meet I wwld hope to have an opportunity to clarify

(Thank you

Whon next we
my pmsent program .)

�</text>
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                    <text>July 1n,

Mr. Harold E.

Childam, President

Bio—physical Research

P. 0. Box 36010
Huston, Texas 77036

Instmnts ,

1955

Inc.

Dear Mr. Childers:
Dr. 11:11 and I have read the descriptions which
have
sent us with a great deal of interest. We
you
will both be available up until July 31. Would you
please plan to stop by and spend some time with us,
any day except Friday?
We

am looking forward to your

visit.

Sincerely yours ,
Fink, Md).
Professor of Psychiatry

Max
HF: kp

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                    <text>July 13,

Mr. Warren 'Ihotmsm

Missouri

Institute of Psychiatry

1965

‘

University of Missouri School of Medicine
51400 Arsenal Street

St. Denis, Missouri

63139

Doar Warren:

Enclosed are two envelopes for Dr. Nagy, which
include his checks for the months of July and August.
Insofar as you are now supervising the handling of
these funds, it may be helpful if you would pay
-

Dr. Nagy

at the end of July and at theond of August,
satisfactorily ooupleted his training

provided he has

during moss periods.

If, for any

reason, he should not be paid these

fmds , would you please return either or both checks
to the Foundation for correction.
Thank you

for your oo-operation.
Sincerely yours ,
Max

Fink,

M.D.

Executive: Director
MF:kp
'

enclosures

.

�</text>
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                    <text>July

13 , 1965

Donald F. Klein, 14.1).

Director of Research
Hillside Hospital
P. 0.

Box 38

Glen Oaks,

mar

New

York

Don:

is possible and I believe that mch of the
either at the University or even at our own
laboratories if the analyses are small . The problem is not
one of whether, but by whom. There is little problem in
Everything

work can be done

winter time or in carrying out the actual naming
of the malysis. The major time maimed is in the preparation
for an azalysis and I dare say this is the biggest bottleneck
in the analysoo that you may need.

obtaining

‘

However, I will do the! best I can. The Hillside material
has been transferred from cams to a set of tapes which are
now at the University. I will have those run off and send
you a oopy. The various item will be coded according to our
problem numbers and them should be no problem in identifying
the various pages. Hwevor, as soon as I have such a capy I
will who what notations I can and then send these to you.
For any of the items or all of them, you can have a duplicate
tape or a duplicate set of cards, if you wish.

leisure time has overwhelmed me with the
desim to oomlete Irony projects , including; the recent submission
of the tri—hoopital study which has been accepted by tho Melvivu
06 Gmmz Plymmy and for which both Bob and Nat am thankful.
My

new found

My

best mgards.
Sincerely yours ,
ﬂax Fink, M.D.

Professor of Psychiatry

HF:kp

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                    <text>July

Cal~Bioohem
3725 Medfom
Los Angeles,

Street
California

13 , 1965

90083

Gentleman :

I have recently hem interested in studies with
cyclooer'im , and have contacted the Ely Lilly Germany for
their advice . A recent report suggested that the 1~form
of cycloaerine would have amusual central nervous system

effects in

man.

I understand that you produce this oompomd, and
appreciate a quotation in quantities sufficient for
clinical trial. From the available literature, the usual
dosage would be 200 to 500 milogmm per day for a ten to
fifteen day period.
would

Thank you

for your co—opemtim.
Sincerely yours ,
Fink, PM).
Professor of Psychiatry

Max

MF:kp

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                    <text>July 12,

1955

Mr. Robert C. Zwahlen

Madical Liaison

Staff

Clinical Investigation Departunnt

8 anch Laboratories
1500'W1ng Garden Street
wadelphia, Pennsylvania 19101

Smith Kline

Dear Bob:

I

sorry that the timing for our visit seems so
inopportum. After- speaking to youmut August 10, I have
discussed this with Dr. Itil and find that he will not be
available at that time. While I would not object too strongly
to leaving the bead) to come to Philadelphia, I really wonder
if this would be helpful to us?
am

I will nuke whatever
and
you
your associates .

armgemnts are most suitable for

In the maritime, I think it was better to cancel the hotel
reservations and for me to return the check for $17u.09
(SK? A 87632), which

is enclosed.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

111’sz

enclosum

�</text>
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                    <text>July 12,

1955

Dr. Keith H. Selmert
Assistant Medical Director
Dorsey Labomtories
Lincoln, Nebraska
Dear Dr. Sebnert:

to having you visit us on Wednesday and
suggest that you come to the laboratory about 10: 30. We have
a case conference from 9:00 am to about 10:30 am every Wednesday
morning. You are welcome to join us at 9:00 if you like. We
would be pleased to have you audit one of our cases.
I believe we can complete our discussion in tine for you
to leave at 2:15. We look forward to having you visit us.
We

look forward

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

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1965

Hr. Max Potschok
Argosy Tram]. Service
1an Hiddlaneck Road
Gmat Neck, long Islmd
Dear

Max:

Complications have arisen

in our

summer

plms in that

mdomtthinkthatmcmtakeourjointtxﬁptommo.
In
have

received another invitatim
part, this is became we
togotoGammyattMendofOotobarandm‘. Itilandl‘
would probably prefer this latter trip . We mot afford
both.

Themfm, would you please cancel the msewatims
thatyoutnvemdeformtoleaveinAugust. Withintl‘a
and: ten days I should lam mom about whether Dr. Itil
and I will he going in September or October and I will
write or call you at that rim.
Sincerely

yum ,

Fink, M.D.
Professor of Psychiatry

Max

HF:kp

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u’»‘~.-r':“;—: ,_/.~.-.w.~.—_

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July 12,

,

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Dr. 8m 1min

Professor of Paymiatzy
Omgon 801ml of

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mew,

Oman“

Maine

DoarSm:

Iwouldlikemtakeﬂﬂs opportmitytoﬁzmkyoufor
your my Wastes during my visit ta 3mm wonderful city.
Icnjoyedwviaitmmdu, deMpetha’cmeaudience

m animated

as

much

as

I

was.

Itwaskindofywtoﬂmmﬂwkdimmmr. I
dompomtthemymllpmblmimcmntinmvingto
and I look
solved quickly for

Laboratory m
you,
m
{Wmhouingofmmh
mile we will not be taming Want this amp, I told
and I would)» faolish if I did
mm of your invitatim,
foratriPWest,hopefullymxtamr.

a

notwitasafm
My

best regards.

Simmly yours,
Pink, 14.1).
m
Profuse? of Faye-Matty

i

”Exp

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�</text>
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                    <text>July 12,

Mr. Robert

1955

601mm

Vice President , Research
Nysco Laboratories, Inc.
3R4“ Vernon Boulevard
Long Island City, New York 11106

Dear Hr. Goldman:

I am pleased that we can undertake
and ethaverine as yau requested.

this trial of papaverine

The easiest way for this laboratory to establish the cost
of any study is on a fee for each EEG moord requested. In
this my, the study can be made larger or smaller based upon

the statistical needs of the user. For studies of this kind,
a single fee of $115.00 per record would include the recording,
fees for tha subject, couputer analysis, and the statistical
malyses as may be necessary at the and of the study.

I nape this will be satisfactory, and look forward to working

with you.

Sincerely yours,
Pink, H.D.
Professor of Psychiatry
Max

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                    <text>July 12,

American Phn

of Scienm

Arizona State University

Tampa, Arizma 8528).

-

1968

Annex 15

63mm:
Encloaad is a carbon copy of the biographical sketch
submitted to m for oomctim. Since Jamar-y 1, 1965 my
title and position have changed at this center. The Missmri
Imtituto of Psymiatry has been mdesignated as the "Deparb
mat of Psychiatzy at the Missouri Institute of Psydxiatzy,
Univnrsity of masouri School of Moira." I am no longer
”Dimmer" but carry only the title of ”Professor of Paydaiatry"

ofmmpumnt.

m position at Washington [hivemity as Research Professor
of Psychiatry continua; communtly.

I would appmaim your making the necessary corrections
in this cditim. Thain you for your can—operation .
Sinoamly yours ,
Max

Fink,

MA).

meeasor cf Psychiatry

�</text>
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                    <text>July 8.

Dr. Lewis 8.
22

Fairom

1965

Start

mu, mm

mm:
Wisammmmwimhloticmtmn
lamb-on.
for our

the staff,
M1Kimitci.joinod
WWO!
unthismckfm'mzm. mmmm”mﬂt'
Dr.

fmwuipwﬁlmpelutm.
WWW.

Sinner-1y

mm W
Mn:

MP: 3m

m,

Pink,

11.1).

�</text>
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                    <text>July 8, 1965

Dr.

J.

Robert Henson

Assistant Director
Clinical Investigation
McNeil
, Inc.

Modes
Road

Cm Hill

Fort Washingtm,

Bar

Pmylvmia 1903‘:

Dr. Hewsonz
Wu

and wish

meshed the additional supply of trifluperidol,
to thank you for your assistance.

have

Your letter of June 25 indicated that you wwld be in
Midwest
the
between the 12th and 23rd of July. Hy present
requires an to be away on July 19th through the 21.31:.
I would be pleased you could visit us before that date or
on the 22nd or 23rd.

3W

if

Sincerely yours ,
ﬂax Fink, PM).

Professor of Psychiatry

�</text>
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                  <elementText elementTextId="104777">
                    <text>July 8,

1955

Free, Jr.
Statics: Head, {Statistics Section

Dr. Spcmer

11.

with Kline

6

French laboratories

1500 Spring Gardan St .

Philadelphia, Pennsylvmia

19101

Dearﬂike:
Enclosed

m the actual data sheets in the malyais
study. For each of the subjects them are two
EEG

of

our first
analyses labeled leads 2-8 or lead: 1-2. The ”2~8" is the analysis
of the frmtal-oocipital lands and "1—4" of the biofxmtal. Each
of tha sessions were analyzed for each of the two leads. Theme is
one lead minimum raising on one of the subjects because we had
a faulty motion.
SKIP

tion:

ms,

the additional identifica—
In additim to the subjects"
the drug aﬂnistemd (SKY ~l, «2, ~3, 4).

m

0n subject A-l (HcDamell) I have marked in rad those scams
which we have key punched and which an available to you in our
format
you wish to rave them.

if

I

look forward to

visiting with you

on

July 20.

Sincerely yours ,
Max

Fink,

PLD.

Professor of Psychiatry

Mthp
enclosure

�</text>
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f

i]

July 6,

1965

Lamina Bouthilet, Ph.D.

Chief, Natioml Clamﬁngmse for
Mental Health Information
Rational Institute of Mental Health
Bethesda, Marylmd 2901“

Dear

Lomim:

for the printout of recent articles
a side affect of
payctnphmceutiaals. This is quite helpful and I have
asked my associate to mad
of the references which you
Thank you very much

concerned with chmgo

have suggested.

in

body weight as

m

Sinc‘emly ycmrs.

PM ’ n
m
meesuof‘ of Psychiatry
O

HPmp

DI

�</text>
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                    <text>July 2,

1955

Dr. Richard P. Emits

Why
Tomes.»

Dopamm: of
Wivemlty of Tmsm

Hamlin 3,
Dear- Dr.

wits:

was pmoomzpied with the problem of
At
convulsive mum.
that time. I reviewed the
and proposed a model based on some of my axparienoas with
mtiamlinergio drugs in patients mo had received electron
shock. The View that I developed at that time indicate that
mmmimofeloctmarnokthcmpymywryﬁn dapemdcn

Sou year: ago I

litemm

W

cmnmrgiomohmimofﬂubmin.
Inmsponoetoour
New
lympoaitm in

mwr mlntcd)

York

I mvieuad

and have

mud

bring this report up-to-date.

earlier mpot‘.‘

my

n amber

of

(which

to

I

thakingﬂnlibertyofsendingywaoopy, withthe

mqunst that if you have the opportunity to mad it, I would
be pleased for your oomnts, suggestions, md corrections.

m

I trust you find this report of
interest.
mm: you very much for your assistmeo, md

personal mgards.

my

best

Sincerely yours ,
Max

Fink,

M.D.

Professor of Psychiatry

HF: kp

welcome

�</text>
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                    <text>July 2.

1955

Dr. A. Arthur Sugomm

Chief,

Imstigativo Psychiatry Section

of mum): in Naming 8 Paydmiatry
old New Jenny Newﬁydxiatric Institute
Bureau

Box 1000

Princeton,

New

Jersey

Daar Art:

is self~explmatozy.

mm
I will met

The enclosed

send Dr.

Hay

I suggest that

a cepy of your auriculmmim.

you

pleased if Gordon Merisson would considar
joining us. for since our breakfast in New York, I have received
only mutant mﬁmnts concerning his work record from scan
be

of

mm}. aoquainanaes
'Ihank

in
you once again for

New

York.

ramming him.
Sincerely yours.
Hm:

Fink,

H.123.

meassor of Psychiatry

unclasum

'

�</text>
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                    <text>July 2,

Join

1‘.

1965

Monroe, M.D.

Amoiate radical Dhaator
m Squibb Institute for Medical Research
New

Brxmmiok,

New

Jersey

08903

Daar Dr. Monroe:

Myouforundingmtminfomﬁmmﬂupmzim
and
Dr. 11:11
amt-hate. My

demons

associates.
ﬂuphamzim
haw twinned this information m we are
inclined to
diamante.
a trial with
This immunim is hand on tha findings of Dr. Simpson,
indicating ﬂat the «mate produces longer iwrovamt with
femr sick struts. Is this Mansion justified by aﬂnr data
and Dr.

that

chdmr

you

If

mm

nWir-n

aimt lava?

no, as mum be pleased

to have you send us the proper
classmate for our pm~

inmtigatiaml forms and supplies of

liminuy trial.
I will be available in St. Louis during the moth of July
and look form to having you visit.
Sinecmly

yum,

Pink, NJ).
Professor- of Psychiatry

1%}:

“Pump

,J‘W

m: Dr.

Ir.

»

-

'1

'r-

'nxymr‘

u

,
~.-.

.

s

“:r‘

,
K

up:

l-M-nwnrz-z"

"r:

)‘V'

Itil

Keskimr

�</text>
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                    <text>,

July

2

, 1965

Albert A. Kurlmd, Md).
Director of Relearch

upset-mm of Mutal Hygiene

Spring Grove State Hospital
Baltimore 28. Maryland

e.

v

"warm—w

Jr.

.*

our,

Dear-Al:

I was vexy pleased to remive your letter, as I think that
the convulsive therapy mdel has been studied too little.
As I see the convulsive therapy process, change: in brain
functim are a necessary. trough not sufficient condition for
iwmvcmt. 0f the various measures of brain fmction, changes
in the electroencephalogram seem to be the met easily quantified
and
sensitive available to us. Induced cmvuleiccs
the
produce high voltage slow wave activity in all parts of the head

ms

this can

m

easily measured.
The data indicates that in the absence of the development
of him voltage slow wave activity, behavioral change is limited

and

be

and appears with no greater frequency than in control gxoups

.

lhue, the principal predictive value of slow wave activity
line in the prediction that in its absence behavioml improvement
and in its presence, inpmvement may ocmr.
will not

cm

The principal predictors of the type of behavioral change
which we call improvemt, and mm: is gemmlly associated
with euphoria, denial, decreased tensim, immved sleep, 239'

are psymolcgical duraotezietice of the subject . Such
characteristics as propensity to denial. high degrees of
anthoritarimism, low discriminant ability are associated with

behavioral

WW”: when

EEG

slow wave

activity is induced.

third set of peremtere in the convulsive
therapy process having to do“ with the mintenanoe of behavioral
improvement once the physiological signs have returned to prettmatmnt levels. These may not have to he considered if the
study is focueeed on the short term treatment results.
There are a

�Dr. Kurland

July 2,

~2—

1965

Your letter reminds me that I should have codified our
convulsive therapy experiences many years ago but not having
done so, I met send wu a water of reprints which am enclosed.
I hope they are helpful.
As

to your kind invitation to visit with you, I

was

at ﬁrst

inclined to regard this as a gesture. I have thought about it,
however, and my interest in the convulsive therapy process has
recently been stimulated, not only by your inquiry but by a
similar inquiry from Dr. A1 Freedman. I have already agreed
to visit with him and to assist me of his students in a study
of conwlsive therapy. I would be very pleased to help you and
Dr.
I am very such interested in finding out if
models
our early
still hold true today,- and if your studies

133le.

can shed some light on those issms, I would be very pleased.
For this reason, may I suggest the following. I plan to be in
New York some time in July and can
arrange to come and visit
you in association with that trip. I also will be on vscatim
intheEastmringMgust.
spend
a few weeks at the bead), and I knw my cum personality well
«rough to anticipate a mstiveness after two weeks . Nothing
would please no more thm to com and visit you for a day in
mid-August.

Wmdlmplarmingto

I hope trace amounts are helpful and I am delighted that
you are undertaking a convulsive therapy study program. Good
luck!

My

best

rem.

Sincerely yours ,
Fink, NJ).
Professor of Psychiatry

Max

Hfﬂtp

�</text>
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                    <text>July 2 ,

1965

Dr. mo Monomer
£033

Heribomwl Street

Boston 15, Hessedmeetts

Deeruo:
Following your report at the Society of. Biological Psymiatry,
Dr. A. Minn? Supmen. for Worship
I m pleased m
in the Society of Biologioal Psymietry. Dr. Sugomen is Chief,

mud

Investigative Peydxietxy Section, of the New Jersey Rem—PsyoMatrio
Institutae. Phisemteofthedootomltminingpmgrmettm
Downtm Medical Center.

Immm‘.8ugemmformmthmm,endhm
has made
with a great deal of interest.

foumd his studies

He

oontributiom in the fields of the oleasifioatim of schizophrenia,
studies of m psychotropic drugs, ms and behavior. that of our
association has been related to his studies of new thugs. I have
fieldmddespitethe fact
famdhiemportsmngmbestinm
this
into
he
come
field
recently, I consider him one of
that has
now
of
wounds in the treatment of the mtelly
$10 but evaluators
11.

It is eploeammmmndhismbemhipde mdelightod
Dr.
Pfeiffor in this honor.

to join

Carl

Sincerely yours ,
Hex

Fink, H.D.

Professm of Psychiatry

Hfskp

oo:

Dr. Sugemm

�</text>
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                    <text>July 1.

Dr.

W

1965

P. White

naming
thivanity of Tamas”
Daputmnt of

We 3. Wane
Dear Dr.

Wu:

with the pmblm of
pmmiad
convulsive therapy. Afar that tim, I ruviued the Hanna‘and
amdnlbusdmmofuyexperiamwiﬁ:
who had
electmamdc.
San: years ago

I

was

Wimmc
ﬂuvimttutldavalomdatthattimindimmm
drugs

mind

in patimta

”Mofommtmrmwmmnmmm
airliner-sic ”durum oftm brain. In response to am
symposium

in

New

York

I mvimd

my

earlier “port

(which

murmlatod) andhnwaddadamnberofpmmhsto

I

bringthis apertw—to-date.

Immingﬁnlibemyofmdingymaoopy,withtm
Iwould
it,
mmtmatifyouhawmoppommitytomad
and
bu planned for yam mnts, suggestions,
oometim.
intomt.
I trust you find this report of

m

Myoummtwmmistm,mdwbut

puma-1mm.

Sincmely yours ,
Hm:

Fink, H.D.

Professor of Paydﬂatry

Wzkp

�</text>
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                    <text>July 1,

m. Heinz

1965

Lahmmn

Bummtive Director

meec Peychophermeologieal Research

1025 Pine Avenue
West Montreal, Quebec
Canada

Assn.

Deer Heinz:

Mywvezymdx foreemingmeeepyofyourmview
oftrimpmrine. Aslhednemledgeofthie mumdbefom
I received the when, I read the text with a great deal of
interest. ‘Ihe museum
that I meeived is that this comma
is less of an mtidepmsemt men imiprwmine, but may be useful

W

in

who do not nepend because the anxiety
Waive disorders
to be unumally large

mum

I wmld like to mngmnnete you and your associates for
having undertaken the task of reviewing new mpomds in m
independent fashion in e style reminiscent of our emfemms
of the late 1950' s, mien were so helpful in disseminating the
latest information regarding new
Hwy thanks, and

my

W.

best regards.

Sincerely yours,
ﬂax Firic, PhD.

Professor of Psychiatry

�</text>
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                    <text>July 1.

Dr. Martin

1965

Katz, Chief
Special Stunting Unit
hyabphmlogy Service Center
Naﬂml Imtitute of Mental Health
Hatinml Bank Building
M.

Bahama, Maryland 20013

mm:

man}: you very and: for sending me a copy of the Handboak
Pawuamw Wag Scam. I mm like to review this with
one of my ”Mates, Dr. Holden . Unfortunately, he is now on
vacation and will return about July 15 . I will make every effort
to mtum this campy to you by the and of July, and I nape ﬂat: is
satisfactory. I! not, I can mtum it within a week after mki
am not” for him, although Iuwould prefer getting the cuppa
1y
volum sinus I mtryingtaeducatehimintho
mmiowmmle
prom of rating mains.
95

81ml}! yours ,
Mu Pink,

24.1).

Profasoor of Psychiatry

�</text>
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                    <text>July 1,

1965

Dr. E. P. Domino

Wesley

Professor of
The university of Midwigen
of thneooloy

Dam

P5322 Medical Science Building

Ann

Arbor, Pﬁchigen salon

Deer Ed:
Sane time ego you wrote regarding my studies of oholinergic
mam-Aim in electroshock therapy. As I told you than, I felt
that the original drafts were incumlete mad that I would send

youeoopyessomesIhedtheopportunitytomvisetMn.
Such a copy is enclosed, and it lacks only the citations, whidl
are

now

being prepared.

I would be pleased to have you review this article and
would be grateful for any suggestions you may have regarding
its mdifioetion. This review was originally written in 1989
when I was preoccupied with the problem of electroshock therapy.
At that time, I undertook a study of spinal fluid eoetyloholim

mm

dxolimstemes only to find that our
were not
enough to provide systematic date. Sud: a study should
hem, Mlmmmimmpmicipeminmypmgmin
whim the biodxemicel changes in spinal fluid during various
drug achinismtions in the courses of electroshock could be
studied. As you will note, I bslim the nodal of elem-—
shock to be one of the best expeﬁmntal models in psydxistric
ﬁning these pest few years I have stepped aside from
mum.
model
this
to devote scum margins to the study of severe longterm mentally ill. I would like now to see some studies in
depressives or other populations in whan electroshock therapy
end

stable

is warranted.

Imelsoenolosingeoopyofthedomntmidxlpmpmd

for the moat symposium on ”Antidolimrﬂc Hallucinogens“
which I chaired at the Society for Biological Psychiatry.
My

best mgards.
Sinoemly yours ,
Fink, NJ).
Professor of Psychiatry

Mex

Mfucp

molosum

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                    <text>Junta 28 , 1965

Dr. William P. Slmley, Secretary
Salaam Medical Association
1700 MM. 18th Strut

washingwn, 0.0. 20009
Boar Dr.

Shaky:

My associates and I were rather pleased to meeiva your
invitation to participate in the next meeting of the Southern
radical Association. We are very much interested in the
subject of EEG and the effects of psychotropic drugs. 'Ihem
am two Imports which could be presented before the 3ecticn,
and I am taking the liberty of sending you two abstracts for

your

midemtim.
ofthe
Ina», wwwldpmmtthemgemmlﬂndings
of EEG
the mods

0f action of these
changes to
relationship
drugs and in the second, examine specific instances of the
of individual
applicatim of these principles to the

mamt

was.

Sinceemly yours ,
Max

Fink,

24.1).

Professor of Paydaiatzy

enclosures

�</text>
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                    <text>June 28, 1965

Dr. Charles Shngass

Departnont of Psychiatry
University of Iowa
School of Medicine

Iowa
'

City,

Iowa

that- (maples:

It

has been

scum weeks

since you stopped

I hope that the Opportunity in Mldelphia
satisfaction.

by

in St. Louis.

works out

to your

After playing with the polarization device that you left
thus any makes. I find that we have observed transient
changes in own patients but which, nevertheless, warmnt mom
intanaim study. I do not believe the effoots are simply those
of suggestion and these currents do, indoed, much and affect
the brain. I have asked our electronics assistant, Mr. Kettman,
to build six such instnmnts and as soon as these are ready, I
plan to do a systematic study in retarded and withdmm subjects.
with In

for
inth
tomdmsomcmngeaintheoloctrodesbutthe satinthe
Sines, however, I have kept your

mmdingit badctoyouinasepmtepadcago.

package functions wall.
My

Thank you

many nooks

for landing these to

best regards for a pleasant

me.

amp.

Sincerely yours ,
Fink, H. D.
Professor of Psychiatry

Max

I

Wehavehad

�</text>
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                    <text>June 28, 1965

Indian 8min Associatim
Dopartnmt of Applied Chemistry
University Collage of Science and Technolow

Calcutta

Gantlm:
I have mad with intemst the establisment of than
Indian 8min Amociatim. (h behalf of my associates at
this Institute we wish to extend our best wishes for your
success. May we ask that copies of Brain News be sent to
us formadingbymambem

ofthis at

.

Sincerely yours ,
Fink, H.D.
Professor of Psychiatry

Hax

Wzkp

�</text>
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                    <text>June 28, 1965

Dr. Andrew Berger

Dimotor of Education and Chief Psychologist
Health Division
Gaga: Stat. Board of Central

mm

Salem, Omgm 97310
Dear Dr. Berger:

I

would

mg to

take this apportmity to thank you for

m

I enjoyed my
invitatim, md to tell you hm
visit. I was very much inspmsged with Dr. miss and the
numbers of the staff whom I met. I emjoyed the tour of the

your kind

I told you, the questions and the mats
cf the pmctitiomm were musually cogent and instructive
to me. If mum of‘the audianca glemed as much as I did
in ﬁgs confemme, I believe you have had a successful

hospital.

As

session.

Dr. Irwin was very kind and shaved me much of Portland.
toumd the radical 861ml, and a rumor of the midential
districts. I fomd the city delightful.

We

I

am

enclosing the variom receipts which you

and a statement of

to

my

mmSan szcisco.
an

night in

the

evening and

Thmk you very man

may need

possible
ewes.
was
overto
stay
necessary
it

incidmtal

It was not

for your invitation.
Sinmmly yams.
Fink, I'M).
m
Professor of Psydxiatry

�Fink, 14.1).
Hissom'i Instituta of Paydaiatzy
5000 Arsenal Strut
St. Louis, Missouri 63139
Max

T0:

Omgm State Board of Control

Jam

25

Jme

25

June 25

Hotel: Partland
San Francisco

3

Bmakfast

Dinar

-

8.00
10.00
2.00
7.00

'

Taxi expenses in St. Innis

$

3.00
3.50
33.50

�</text>
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                    <text>June 30 , 1965

Dr.

J.

Robert Human

Assistmt Director
Clinical

Inmti

Liberate
W1
Cup Hill Road

ation
as. Inc.

Port Washington, Permsylvmia

Dear Dr.
Both

190 3%

Mam:
the.

Dan, 11:11 and

I will be available

duringtiurminderofJuly, andlodcformxdto
your visit.

Wyouvatymdtforscndingmtheadditimal

triﬂwaridol. I will

bring the mange in concentration

O‘an

and the other mentors
to the attmtion of Miss
of the staff who will be: using this pmpamtion.

81:10:me yours,
ﬂax Pixie, Md).

Professor of Psychiatry

�</text>
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                    <text>Jam 30,

Robert E.

Edam,

1965

Ph.D.

Psychophmaoloy Set-vim Gent»
Miami Institute 91" ﬂea-std Hum:
Setback 13, Maryland

Dear Bob:

may
I mtaful

I haw just received

and

an

this to m.
My

III of the Payehm
quite a cuspﬂatim,
for your Wtfuhmss in sending

Handboah.

Volume

It is

best regards.
81130:me yams ,
Max Fink. 11.13.
Professor of Psychiatry

�</text>
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v

an 28, 1965
Mr.

c. J.

Wt
strum,

Financial
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Bethesda,
Dear ﬁr.
We

Special

Bram,

1536th

1mm. Education. ma Welfm
Miami 2001“

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have reviewed yam

lettam of

naming a pmvisioml rate cf
for the ﬁscal yen-ending Jun

May 18

and April, 16

for the
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W13; mm
new expenditms.

pmvisimul rate is

on

156.9%

Femdation

find that ﬁts

for the period based
d

maven. this at. was madam? low because early
in 198%, thé Fmﬁm‘
had .1 very. low cash
we
defemd all expanditms mild» to later balm“.
the yearin
The” will war as part of the accounting forlthe fiscal
year «3311:; June 30, 1965, and will mﬂeet a higher
indium:
‘Ihe
thus fail

ruminatim‘my
warm.
mama!
{12119198541le
WW
exceeds the animal teem
2m. Were this to
willwe

‘

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to must a mviow of the 1983-63; rate and an
allocation of some of the deferred expenditures
to thei
year ending June 30. 1951+?
be able

'

.

at
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u
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will [file an
to June 30, 1965,

We

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our expenditmee July 1,-

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m, Director
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.

Dr. Harald F. Klein

Hillside Hospital
P. 0. Box 38

Elm Oaks,

New

York

Dear Dm:
Ermloaod in the listing of the original Hillside Hospital
we have «3 our tapes. Tm code swat identifying the

data as

item is enamel.

In addition, we already have tapas mien give us diffemnces
batman pm md post on each of trace items, and different scams
calculated from a

If there is

,-.

cam mmssim for all thme mama.

mything alas m can

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xw-«pu

Sincerely

let

yam,

Fink, M.D.
Professor of Psychiatry

Max

link}:

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�.

.

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1

.-

av

July 30,

1965

We
Wtanﬁinws
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Mafmwim
m,ﬂowak

Dar

Bob:

I

was no

plum with the results

of the ‘I‘r‘i-ébnpital

that
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mwitdthmlswwwmifitismmn
to Wait tn one tho paychintric journals?
Of

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cruel-him.
IMpoyouuﬂlhnMppyinmmwposim

MlmmwmitmgwithmtmmxttiuIm
but rem.

manntaohoinChicagm
My

Sincerely
Max

Pink.

ms,

PM).

Professor of

thiatry

�</text>
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mine papaverina‘a action in a darinita 4939 by EEG msﬁhoda,
than it should be passiblo t0 earry out soeand and third
utap nimnltanaoua studios in a group of valuntears the
randomly reaaive either a nonntimed 6099, or triple thﬁ
nonutimad doaa or the timed daae, It dons properly,
aiseriminant function analyaip will datermine uh»
airfarancou or similarity botuoan the three runs.

�[34‘

r-

f

WJWW. w» ”WWW"
w

,

,w,

.

.. . .
W,

“on“.
.

W, ”WNW”,

~v--

we.

Ev. Goldman

m *w‘q‘w-m

'r'

"=xn:~"2~wrnUri-:Anav- .....,_.~.,..“...
_

June 25, 1966

a supply or
an: step can vauld reqplrehave
carry
aortain»
we
ulruady
Sine:
from
undieatioa
yen.
1!
would
be
3K?
your
helpful
vary
anpsule: tram
it
1dantienl
capsule.
tha
campauud Gould be put up in
roanen, I am sending yum a samplo or an: 3%?
Eb:
$0

m3.ibis

.

I would be
to the cast of such initialtrial,
Our
volunteer:
pleased to do it on tbs aoat basis.
arm paid.at ch» rate of $3500 an hanr. Our laboratory
toahnieiuna and incidental asst: avarage $5.00 an hour*
At tho praaant time for uni; step of tha inventigntion
we vuula make no charges far our aompuhar ar.other
ganarnl laboratary casts. Ir tho initial trials raqpiru
fbur
five subjects. tun trials par subﬁaatg avuraging
thay
hawavnr.
$400.00:
haurt. tho cost may approximate
Eh»
mars
it raunlti
any h. lens 1! '3 tall ané slightly
banana ales» qn1¢k1y*ana yo decida-ta dn'many samples.
tbs initial ﬁriala araﬁnatiufnctary, we will
It
vaguent &amp; aonsultation tag of gvso.ao.
these pralinanary data urn mutually satisfactory,
If
budgat¢d to pravida support
the datmnitivo teudy will beand
ear nﬁuraphyaiology
opanationa
tar our computer
raga»
direct costs and aonaultation
laboratory dbovo thoknow
1a
a
zabcratory
ﬁhat this
I think yam thauld
the 931%.
unit and'that in with
university Iuppartad raaaarah
out
been
aurried
have
A3

'

-

such aonsulhutiena which
with sum: of
pharmaceutioal aanacrnc hnva providad.un
man
we
new
nae in tho
aha apacialisod aqpipmant ﬂhioh
otudiao suggested in this letter.
assumption as em 833m}:
I am. mama mm your
pram" vary interesting and I am leaking 20mm to
'

this study.l
I trust chit intbrmatioﬁ is sufficient. and lack
forward to napkins uith you.
Sinenraly yaurs,

“,—

V”.

Pink, 11.1).
“3
Protbaaar of Paynhiahry

..

&gt;

m“

A,“

M

.y‘

k

“1,2,

(ﬂu.

.

.

'wmm-‘N‘Wﬁo-my—yr

uFlkp

.,;..-....»

~

,vu— «an

“at“,

ww-

-—.

~

~—

.—

�</text>
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                    <text>June 2», 1965

Mr. Robert C.

Milan

Medical Liaison

Staff

Clinical Investigation Departmnt
Smith Kline E French laboratories
1500 Spring Garden Street
Hailadelphia, Pemsylvania 19101
Dear kl):

associates and I have and the painstaking ccuments made
his cam-workers. This study should be repeated.
To do so has became a matter of high priority for us and we have
already issued a cell for volmteers. We may even repeat the
study in some of the sane subjects.
My

by Mike Free and

However, we will try to control those variables which we
believe were the problems in the first study.

so will require some additional supplies. Since I
have eight sets of the drug available, perhaps you would like
to send us the em material but coded differently, and if you
To do

wishtodoso, thatwouldbeagmeabletous.

In doing this study, however, we would like to add an additional
We are anxious to determine the differences between
barbiturates and central stimlmt‘s. We are interested in knowing
techniques will discriminate. For this reason, I vmder
if EEG would
consider supplying us with 20 sets of a SKY-5
you
if
which includes 10 m of chxtmazphetandne.

cmditim.

If this is feasible, I muld also like

you

to send

me 200

blank capsules so that I could nuke up a sixth sample containing
an experimtal stimlant which is of interest to us.
'

Would you
Hy

call

me

early next

week

to discuss these questions?

best regards;
Sincerely yours,
Max

Mfzkp

cc:

Fink,

M.D.

Professor of Psychiatry
Dr. Spencer

M.

Free,

Jr.

�</text>
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                    <text>Juno

2!»,

1965

thlcn
Liaium Staff
Meal
(minimal
Mr. Robert C.

Inwatigatim Department

ﬁlth Kline 8 Much laboratories
1500 krin Garden Strut
19191

Winchlphla, Pamsylvmia
80!):

Dual."

My

associates and I have mad tha careful cements

made by

Hikeﬁumdhiaeo—womm. Aamplamed, wwuldlikoto
take thn next step in this study. amtmling those variables
which a: banana mm problem in the first study. Arc than
additional suggestions for this pins. of our program?
To amtinm the study we envisage, will again
wplios. Since I only law 31:: sets of the dmg available,

any

Mtiml

pcmpsyoumuldlikemmdthammﬂalbutmad
that maid be
If you wish to do
diffemtly.

agreeable

no,

to us.

In aging this stray, hmvar, we would lit: to add an additional
audition. ﬁt an madam to «mom the diffemoes batman
would yau
Whitman and contra “haunts. For this

commu- supplying us with

labahd "mm-s."

30

not: of

10

m

or!

am,
daxtmmkmtm,

Ifthis is

feasibls, Imuldalaolikcyoutomdm 200
Naipaul” thtIoouldmkaupaaixthaamla containing
an experimtal nimlant which is of interest to us.
Would you

ﬂy

but

call as early next

week

to discuss these qmticms?

regards.

Simemly yours.
ﬂax Fink, PM).

Professor cf Psyehiatry

PEEK}:

an:

Dr.

ch

Dr 11:11

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                    <text>June 2a, 1985

Irene E.

Waskow. Ph.D.

Research Psychologist
Psydmophamaoolow Service Center
National Institute of Mental Health

National
Bethesda

Bank

1%,

Building

Maryland

Dear Dr. Waste»:

timing the past year, I have been swam that you have been
writing a miew of language changes with LSD. My associate,
Dr. A. Dan, is presenting a report of our recent LSD induced
changes in EEG and “HR at the divisional meeting of the APA.

helpful to us if a copy of your report could
available to him. even before it is published, so that
he can place his observations in their pmpsr content and,
incidentally. give credit to PSC for your efforts.

he

It would be

made

man}: you

for your help.
L

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

Hszp

�</text>
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                    <text>June 2“, 1965

Mr.

Irwin Schwartz

York Medical College
5th Avenm at 106th Stmst
New York, New York 10029

New

Dear Mr. Soluar'tz:

I enjoyed

my

visit on

Monday

with your

staff,

and indeed

the only disturbing note was they news that you were having
some diffiwltiss with the building on 105th Street.

Dm‘ing the day I not with Dr. 'Shamff and his associates,
Dr's. Sorvino, Solmsdek and Major. modisoussim centered
about the two principal research program planned by Dr. Fmedman~

blocking of heroin addiction by oyclazocine and methadone.
Dr. anroff and his associates have had some mosual results
in their first group of nine patients.
There

is

need

for mplioatim, and for

some

additimal

studies to oognplsmnt the clinical observations. Truss types
of supporting studies were discussed: biochemical examinations
for X's-exposure to heroin, psychological tests for the evaluation
of personality of addicts who any or may not respond to such
studies to masons the duration
tmstmt and murophysiologiosl
of blodcing notion. Dr. Shaxoff and his staff are well equipped
to omy out the second and third parts of these ancillary program
but will probably need better supervision for the biochemistry.
if codified,
It seems to me that their experience is sufficient,
NIH
of
the
an
to
planning
application to
or to other

mt

for support with which you may be acquainted. I left
scum
Dr. Sharoff with the mooamdstim that his associates write

upeaohofﬁmnijmoasesinashort
I muld

be pleased

to

mview these.

‘

(2 page)

swansryandthat

Dr. Stamff invited as to sit in on his staff meeting,
following which I lectured on the subject "EEG in Psychiatry,"
During lunch with Dr's. Scrmeok, Losmnkopf , Shamff and Sowino,
m oontimnd to discuss the drug addictim problem.

�Mr.

Irwin Somartz

~2—

Dr. Sorvino presented the model

June 2a, 1965

of establishing an

EEG

laboratory for clinical investigation. I indicated that it
was probably difficult to establish a second clinical BEG
laboratory at Metropolitan Hoopital, but that a research
laboratory dedicated to the problem of the drug addict or
to the other projects of the department could probably obtain
support. It became clear that Dr. Servino was very Immh
interested in carrying our neurophysiological studies in drug
addicts. To assist him, I gave him some reprints of work that
might be helpful to him. I would like very such to continue
our discussim at the next meeting.
his interest in 1301’. At an earlier
visit
interested in carpeting Indoklon convulsions
with electrical convulsions. After reading sous comparative
literature and in the worse of our discussion he seemed to
focus more on studies of the mode of action of ECT. After
describing my experiences at Hillside and the corroborating
studies of others, we seesed to agree that a predictive study
of the EC! process could be undertaken at Metropolitan. I
indicated that to types of data would be necessary, psycho—
logical tests and neurophysiological indices . It was apparent
that if Dr. Sorvino established a research EEG laboratory,
Dr. Schneck could obtain the necessary EEG data. For the
psychological test data, however, he would probably need the
collaboration of a clinical or experimental psychologist. He
suggested that he arrange for the three of us to meet during
my next visit.
I also pmnised to send him sons literature
which I we doing under separate cover.
Finally, I spent some time with Dr. Ioewenk0pf. We discussed
his program of drug evaluation in the out patient department.
As he described his interests it seems that he is less interested
in the testing of new ccnpomds than in developing predictors
for the application of the drugs. We discussed the Domstate
Psycl-ophannacology Program and also some of the behavioral
typology approaches developed at Hillside. Since Dr. Sorvino
already had the references from Dr. Overall, I suggested that
be «mad Dr. Sorvino get together. Since I know Dr. mgelhardt
well, I indicated that I would write to him and obtain sure of
his reprints. I also suggested that I would send Dr. Loewenkcpf
some of those from Hillside and that we should be able to
oontinm this dialogue after his vacation.
Dr. Schweck discussed

he seared

�Hr. Irwin Schwartz

~3-

June 2'4, 1965

I am inpresscd with the enthusiasm of your staff and believe
that a umber of projects can be stimulated. It may be advisable
for me to return to New York in mid-July, to meet with some of
these staff numbers and any others that you would care to recommd.
The date is probably irrelevant and I can suit your commence
(:1 any Monday

or Friday.

I had the enclosed

forms with me

but decided to send

you personally as Dr. Freeman had requested.
am

to

also enclosing a statement of my expenses for this trip
well as a receipt for the air rpmspcrtion.

I

am

'

Sincerely yours,
Pink, M.D.
Professor of Psychiatry

Max

MP:kp
‘

them

enclosures

�DEPARTMENT OF PSYCHIATRY
NEW YORK MEDICAL COLLEGE

Expenses in consultation and lecture June 20/21, 1965:.

Air Trmsportation

$108. 00

Gmmd Trmsportation

8 . 00

Total

$116.00

�</text>
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                    <text>11:.-

5:."

-“~Ls\—.~wnuvm‘

hwy:

June

2%, 1965

J. Sameigm
Depaxmnt of Clinical Investigation
Parke, Davis and Ccnpmy

Dr. Alain

2800 Plymouth Road
Ann Arbor, maxim

Boar Dr. Smeigne:

ﬂunk

«mules.

web for your supply of 20%
per cc of Semyl, which we received

you very

10 mg

in satisfactory condition

on June 22.

Sincerely yoﬁrs,
Max
4

HF2kp

Pink, M.D.

Professor of Psychiatry

�</text>
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                    <text>June 20, 1965

Smear H. Free, Jr.
Section Head, Statistics Section
Smith Kline 6 French Laboratories
1500 Spring Garden St.
Huihdelphia, Pennsylvmia 19101
Dr.

Dear Dr. Prue:
Dun Miro, Tum Itil and I wish to thank you for
your
thoughtful and painstaking review of our program Import. We
have mvimd each of your
and I shmld like to upon:
our mlusims.

mix

The lack of discriminatim of the 308 mg sustained release
hours maultcd ﬁres the variability in sleep. I thfmk
four
at

this is clear in our critique. It is an important question to
us and it is our feeling that u should axtend our study with
the mdifioatims described in am second pmgram mpor-t.
th- statistical

of your suggestims, sad we now plotting the "F”mpted
values for
ouch discriminant solution that used all the variables. We
are also planning to run some of the additional single variable
Regarding

calms (t-tests)
Thank you

that

comments,

we»

have

two

are omitted.

for telling us about the amt-a in identification

of tables four and five.
With regard

to the data that

you wanted,

I have asked

Mimﬂickmmtoeopyalltludatasheats andthesewillbe

town as soon as they am available. I will be glad to
send you the cards that are already pmcl'nd, but these reflect

aunt

mly a small part of the data. She will indicate What is
already on earth and if you wish them, we will dwlicate andsntmit them to you.

If you have

additiaml suggestions regarding our
pleased to dismms them.
was again for yaw interest.

continual study,
Thank you

any
we

mid be

Sincerely yours ,
Max

Fink,

M.D.

meessor of Psychiatry

Hszp
00:

Hr.
Dr.

2mm
Itil

�</text>
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                    <text>June

2s,

1965

Jr.
Statistics Section

Dr. Spencer-M. Pros,

Section Head,

anith Kline

8

French Laboratories

1500 Spring Garden

St.

mindelphia, Pennsylvania 19101
Dear Dr. Pme:

Shapiro, Tumn Itil and I wish to thank you for your
thoughtful and painstaking review of our program report. We
have reviewed each of your commts and I should like to report
our cmclusions.
Don

,

The lack of discrinﬂnation of the 300 mg sustained release
four
hours resulted from Our poor control of behavioral omat
mitants, including variability in sleep. I think this is
clear in our critique. It is an important questim to us and
that we should replicate this study with the
it is our feeling
described
mdifioatims
in our second program report. While
we thought it would be important to take recordings during the

hour, your comments make it clear that this would not be
necessary but rather that we extend the recording heymd four
hams, perhaps to six or seven; and, indeed, perhaps to record
the subjects at eighteen and tmnty~four hours for additional

first

samples.

‘

Regarding the

-

statistical

mots,

we

have accepted two

of your suggestions, and are now plotting the "F?’ values for
each discriminant solution that used all the variables. We
are also planning to run some of the additMal single variable

(t-tests) that were omitted.
Thank you for telling us about the errors in identification

analyses

of tables

four and five.

v

With mgaxd to the data that you wanted, I have asked
Miss Hickman to copy all the data sheets and these will be
sent to you as soon as they are available. I will be glad

send you the cards

to
that are already punched, but tress reflect

�Dr. Spencer M. Free,

only a

Jr.

mall part of the data.

on cards and

to you.

if

Jtme

~2-

you wish them,

She
we

will indicate

what

2M, 1965

is

already

will duplicate and sutmit them

'
_

that your review engendered,
with
some of our statistical techniques and
was a dissatisfactim
our desire to replicate this study. As you will note fun the
letter which I an sending to Mr. thlen, I am requesting additional
supplies and I trust that this second study will clear up sons of
the questions presented both by ourselves and by you and your
Perhaps the most importmt feeling

associates.

Tram you owe again for your interest.
Sincerely yours ,
Fink, 11.1);
Professor of Psychiatry

Max

Hfzkp

co:

Mr. Robert

thlen

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                    <text>June 2a,

1965

Sanbom Division
Hewlett-Packard Oonpany
Waltham, Massachusetts

Gontlennn:

I would appreciate a ample of the new Sanbom
for trial in this laboratory.

Redux Cram

Sincerely yours ,
Max

Fink, NJ).

Professor of Psychiatry

�</text>
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                    <text>June

214,

1965

Medical Department

Wanner-Chum
sz'r'is Plains, New Jersey
Gentlemen:

I have read your advortisemnt describing the
action of dalomhentemine (Pro-Sate) with considerable
interest. I would appreciate a supply of this oompomd
for clinical trials in quantities sufficient to assess
its effect in five subjects ovér a month period.
The advertisement indicates that the CNS side
effects are less than mphetamine. I would be interested
having the data which makes this conclusion possible.
in
Thank you for your assistanoo.
Sincerely yours,
Pink, H.D.
meessor of Psydxiatry

Max

HFﬂcp

.

�</text>
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                    <text>June 23, IMS

Mr. S. C. Sachs

Sachs Elna-trio Cwmy
ssno West Park Amman

St. Innis,

'

,

Bur Hr.

Mam 63110

Sachs:

I stmldlika toioinﬂzuﬁanhe inexpmssingtha

forymrmm
.mjmpmimofﬁufmofmrmdatimmmw
being used to provida
which
thaw oftha Famdntim

gift.

equimmt for projects

devaloped during the past faw maths.

A

have

cmtr‘ihmlm
will be met helpful in making available to the scimtists
"tin facilities that they mquast for thnir Hark.
Your

‘

.

Imlda‘laoliketoMyouformmoogmt
and 1mm during your meant visit. Yum

qmtims

stimlntim provided the M19 for. our prom of pmMidas making it possible to
minute with fellow scimtists more rapidly.
wblioatim of

mm

Sincerely yours,
Max

ﬁnk,

PM).

Wive. Director

:

Hfucp

-

.

�</text>
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                    <text>J1me 23, 1965

Hr. Donald G. Irvine
Research Biochemist
The Saskatchewan Hospital
North Battleford, Carmda
Dear Mr. Irvine:
Thank you very nuoh for your letter of June 21. It would
indeed be possible for you to visit these laboratories , but
the period you suggest in mid—August is a tine when both Dr. Itil
md I plan to be away. We would be pleased to have you visit
these laboratories before the end of July since we plan to leave
about the third of August or again after the tenth of September,
men we will have mtumed from some meetings.
EEG

Your statement that you are interested in the genetics of
patterns is an interesting one. I wonder if you would tell

mmmmehoutwmtyouhavebeendoingandifyouhaveany

reports omoeming your work, both Dr.
pleased to read them.

Itil and I mid be

Sincerely yours ,
way-h

«4"W'ie‘.

Fink, M.D.
Professor of Psychiatry

Max

Mfzkp

�</text>
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                    <text>I,

June 23, 1965

Mr. Harold C. Hanks

331th.

lands

#11 N. 7th

St. Louis,

8 Bake
Street

Miami

Dar Harold:

mimions
mgamding our overhcad allomce. Also,
Mon
aprwiaiamlhttcrmichlmldliketomdtow.
Finland are ﬂumofax copies of the

with ﬁr.

Stmttcn is «reload.

pleas edit this letter
into the tcdmical language which will
best
pmtoct the Fundatim's intemst?
I monived your letter and Hr. Sachs' ahedc this

and comer“:

it

Would you

-

naming and join you in yum cxpmsaion of meant.
Sincerely yours.
Pink, H.D.
Exemtive Director
Max

Hchp

mlosums

�</text>
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                    <text>~

-~

.n
,,

'1"

-

7"‘3"5V'

ri‘f’hl‘w’

‘
And-W

'f‘ﬁw

June 23, 1965

N

Professor Fritz Flugel
Director, Univemity Nemnklinik

Scmmcrmnlage 10
Erlangen, Germany

Dear Professor Flagelz
Thank you very much

for your kind invitatim to attmd

the next mating of the Deutsche Arheitsgemeinschaft. I have
read the invitation oamfully and believe we have a omtributim
oonceming the theme of data processing. I am taking the
liberty of enclosing the form with the title of a report "Die
Amendmg van Digital Computer Methods in der' Psydwpharmakologie"
which may be of int’emst to the members of the Society. If at
all possible, I will prepare this report in Germ.
My

best regards to

Mrs. Flagel.‘

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

Mszp
enclosure

�</text>
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                    <text>Jme. 23,

Dr. Enoch Callaway,

Chief of Rosaamh

1965

III.

The Langley Porter Neumpayohiatric
n01 Parnassus Avenue
San hmeisco 22, California

Institute

Boar Noch:

I am Messed to have written to you so late
so as not to be able to make the mangemnts to visit
with you. In this afternoons mail I mceived this
mate of Sm Prancisoo and am sending it to you for
your

interest.

'I hope. you won your match; and I look forward to
having an oppor'tuxﬁty to play with you somtime soon.
Sincerely yours ,
Max

Fink, M.D.

Professor of Psychiatry

“ﬁkp

�</text>
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                    <text>June 23 , 1965

Dr. Neil Burch
Houston State Psychiatric
1300 Emu-Md Avenue

Institute

Houston. Texas
Dear Neil:
We

still have

not heard from your engineer.

I are interested in being able to do
period analysis in analog form since we have already
loaded our digital oaaputer to the
Dr. 11:11 and

am.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>w... «1“.-sM-lw-rwm‘ﬂm‘4w‘ ‘rw'll‘mwme1w

..-—

w. mw

r

v

"ma-”u...

L. m“...

&lt;

r—JW

-. ‘.m,_.‘ w‘v‘rﬁ

June 22. 1965'

Commit Aocomting Offioo

National

Instituu of Mmtal Health

United Status Public Halt}: Service
Bethesda, Maryland 20 on

Gentlmm

RE:

Iii-8388431

M1~auau~01

bun

Immitngwiﬁxngardtotheﬁmds tohavu
Mic—8388

by us in grants
mind
to our
us have

‘m,

and MH-eusu.
621.8%

m Mulf of m-ansu-m and $22,320mind
for bib-8388.

Hatch 30. we
an additional advance
of $12,000, mid: has matted
not been received.
On

Rather than

file individml monthly cash

masts,
involwdis m1. muldymfmrm
sirmﬁnmnt
with a singhdudc in tho
of $26,156 which will
30,
mrthemlctimofﬂaeutwogrmtstm
1&amp;5.

wt

For iii-$388, the

total grmt

have monivud 822,320, leaving

PmM-Bhﬁu,

$37,892. it. have
Of 315,3“5.

a

was

332.6%.

We

bum of $10,320.

mwminmmmtof
mind $21,8u6,'1uving a balm
I

Insofar as both those grunts to this romantics:
being
to the
Missouri University School of Medicine effoctiw
July1,_) itmldbohlpfulifthisfumdatimemld

will taminate (the

wt:

mfemd

mist. its mounting this war.
Thank you

for your assistamu.
Sincerely yours ;
Fink, H.D.
Emcutive Dimctor
Hm:

�</text>
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                    <text>June 18 , 1965

Dr. Keith

w.

Semen:

Assistant Hedical Director
Dorsey laboratories
Lincoln, Nebraska

Dear Dr. Sel'nert:
have just been able to make the necessary pmvisiaw to
mdertahe the study of pymvalerme. It will be in progress by
middle of July and we would be pleased to have you visit
with us. Both Dr. 11:11 and I expect to be in St. Innis during
that week. In general, Mondays and Fridays am difficult days
for us. We would be pleased to meet with you on Tuesday, Wednesday
or Tmrsday. If you muld let us know what day you are planning
to visit, we will be glad to have lunch with you.
We

tn

make

Incidentally,

would be

drug.

Dr. Pogge

indicated that he might

interested in any

be able

Sincerely yours,
Max

Fink,

H.D.

meesaor of Psychiatry

Mfdcp

to

If this is so, we
infatuation that is available on this

dibanzothiazepine available for study.

�</text>
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                    <text>June 17. 1955

Dr.

Wm

Bum

Natural Institute of Mental Health
National Bmk Building
6917

Arlinm

Road

Bothwda, Maryland

Dinar Dr.

NW:

intcmt in the application of omputem
mowedmftmpyofampmmimhwmomﬂybmsumimd
for
think
Bil-towing

of yam

bEGmmlysia,'Imtakingﬁmlibertyofmdingywﬁm

wants

publication. I
our efforts earlier this
it
year. Since that tin our pmgxm have been modified so that
analyses are omtinums, can-line. with varying sawle aims and

swung rates.

Sincerely yams,
Hm:

Fink,

M. D.

Professor of Paydxiatry

mug;

Wm

�</text>
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                    <text>.

Dr. Alain

J. Smigne
5

Parke, Davis

Cowmy

June 17, 1965

'

Department of Clinical Investigation

Laboratories
Ream
2800 Plymouth Road

Ann Arbor, Michigan

Dear Dr. Saweigxe:
Thank you very and: for yet»: call regarding Semyl. You
some work was being done in EEG analysis by
Dr. Komin. Perhaps you would be interested in this report
which I have just sent to 816‘ which will tell you something

indicated that

abOut the present Istatxm of our

art.

Sincerely yours,

Fm,
m
Professor of Psydﬁatry
McDo-

Mszp
enclosure

�</text>
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                    <text>June 17, 1965

David H. Ingvar, 1-1.9.

Laboratory of Clinical Neumphysiology
Depar'tmnt of Neurology

University of
Lmd, Swedm

Lund

Dear Dr. Ingvar:
EEG analysis
request for we informtim regarding
by digital water was mfemd to ma by Mr. Shapiro. I am
pleased to enclose copies of sum earlier descriptions of this
work as well as a most meant report.
We on, at pmsent, smumizing our experiences with the
1710 system and will send you a copy as soon as it is available.

Your

Sincerely yours ,
Fink, M.D.
Professor of Psydliatry

Max

MF:kp

enclosures

'

_

�</text>
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                    <text>June 17, 1965

John A. Harris, 14.8.
Mayo

Clinic

Rochester. Minnesota

Dear Dr. Hands:

First, let me thmk you for the samples of younwork which
sent to me. Both Mr. Shapiro and I have found
of
intemst, especially the prediction study which seems tothese
confirm
the validity of your model.
I regret that you have not been able to devote more time to
you have

‘

,

mix problem and I believe we need the explorations of
my mdels
if we are to have better EEG analytic metiwde.
I am taking the liberty of sending you a wpyof a report we
have recently owpleted. While the study
is pedestrian, it
provided

“the

Opportmity to

methods nemesary
My

test the

EEG,

for drug discriminati

.

mater,

and

statistical

.

best wishes in your studies.
Sincerely yours ,
Mex

Fink.

M. D.

.

Professor- of Psychiatry

enclosure

�</text>
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                    <text>June 15, 1965

Dr. Joseph Zubin

Bimtr'ic laboratory

State Psychiatric Institute

New

York

New

York,

722 West

168th Street
New

York

,

Dear Joe:

talking to Jma‘thm Cola about another problem earlier
In this
this week md he mantimed your project on diaguosis.
Grinker
Dr.
from
that the
mmings mail I moaivad mtifioatim
I
taking
am
enclosed "vapor: has been accepted for publication.
this
believe
that
because
I
tha liberty of sending you a copy
make
in
providing
will support my effect that your study grcmp cm 5.11.
objective classification anthem for the mentally

I

wan

My

best regards.
Sincemly yours,
ﬂax Pink,

1-1.1).

Professor of Psychiatry

W: kp

melosm

�</text>
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                    <text>June 15 , 1965

Dr. A1

Silverm

Professor of Psychiatry
Rutgers Univcmity School of Medicine

New

Bmwick,

New

Jersey

Dear A1:

It was kind of you to devote so mch time to acquaint
with your pmgrm. hiring the return trip I melt on the
mum]. oppcztmity your facility pmecnted, and reflected
that with your entrmsiasm. optimism and dedication, the
Departmmt and the Mcdical School at Rutgers will snowed
handmly. Indeed, the pictum of a medical facility as

me

integral part of a university owns in a setting
minimum of the leading mivemities of Europe , is

an

attractive.
My

dm‘ing

best regards, and again

my

visit.

’

'

my

very

thanks for your interest
Sincerely yours,
Fink, M.D.
Professor of Psydiiatry

Max

HF:kp

�</text>
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                    <text>June 15 , 1965

Dr. Roy R.

War,

Sn, Chief Editor
Archives of General Psychiatry
Institute for Psychoaaaatic and Psychiatric Research
291:):
‘

Street and Ellis

Chicagc,

Illinois

Avenue
60616

Dear Dr. Sumter:
Enclosed are three copies of the manuscript entitled
"Sociomychlogioal Aspects of Psychiatric
Treatment in
Volmtar‘y Hospitals," as mquested in
ymr recent
letter. I am also enclosing the mdical abstract
I have pmviwsly sent one to Dr. Dmilevicius, as card.
he had
mquested this about ten days ago.‘Ihank you very mch

for your interest.
Sincerely yours,
Max

Fink, H.D.

Professor of Psychiatry

24?sz

encloma

�</text>
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                    <text>June 15. 1965

Division of 'I‘mining Grants
Public Health Sewioe
U. S. Department of Haalth, Education, and Welfam

ﬁshingtm,

D. C.

-

Gentleman:

W

Would you

please send us a copy of PHS publicatim
lejew,601:.Policy
(Milluwch
and PBS publicat
m 1302 ’
lej'cw '
Policy Statement?
1301,

Gm

85.110:me

Max

Pink.

TmSW,

m
M.D.

,

Executive Director

Mthp

�</text>
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                  <elementText elementTextId="101876">
                    <text>June IS , 1965

George E. Come, M.D.
Frost-m Head
Early Clinical Drug Evaluation Unit

Payohophamoology Service Center
National Institute of Mental Health
National Bmk Building
'

Arlingtm

Road
Bethesda, Maryland 2001a

6917

Dear

George:

Thmk you very mob for your letter of Jme 11, and
article. I have had photocopied and on re—
turning the original to you for your files. We have already
approved a study of dibmzothiezepine, following the moon:—
mendatim of Dr. Don after the 22cm; Meeting and Do. 11:11,
based cu some data he has from Emwope. However, the Dorsey
Laboratories, who represent lunar in the United States,
Dr. Delay'o

it

indicated that this expand is not yet available for study.
as it is, we would be pleased to mdertake a trial.

As soon

and

I

we am planning a trial with oyolooerine
writing to Ivm Bennett today for supplies. Thank you

In the meantime,

am

for yam help.

'

Sinoerely yours ,
Fink, NJ).
Professor of Psychiatry

Max

MF:kp

enclosure

�</text>
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