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                    <text>Member 13, 1966
‘

Dr.

Mom Cattell, Editor

The Jamal of New Drugs
1300 York Avenue
New York, New York 10021

Dear Dr.
My

Cattell:
associates and I have discussed your letter of
There is no objection on our part to the

Novanber 18.

qmstionsmiohyouposed. Whilnthiahaamtbaena
regular pmoedm, wefare prepared to mquest our
institutions to participate in the partial discharge of
actual publication coat.
Thank you

for your- consideratim.Sincerely yours,
Fink, NJ).
Professor of Psydxiatry

Max

Mchp

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                    <text>December 12 , 1966

Dr. Donald M. Shapiro
Washington University
Computer Center

Sever Hall
Lindell and Skinker Blvds.

St. Louis, Missouri

63130

DearDon,~
Kathy has typed your recommendations and we

are enclosing

original draft and the typeacript. I lave made two xerox
copies which I have given to Dr. Freedman, one of which he
intends to share with Dr. Miller.

your

had a chance

He

was most

to see this and after an initial

entlmsiastic.

Dr. Muller

right rm.)

(Indeed, he

is

having lunch with

I have reread the typescript, and I also felt that it read
verywellandthatmycamentsweremchtoomimrtonodify
this draft. Congratulations!
This is to confirm that you have an appointment with Dr. Slobody
and Dr. Preechnan on December 20, at 1:00 pm.
On the basis that these official meetings might be
through
by5:00pm, Imuldliketoaskyoutohavedinmrwithmeand
I would like to invite a nuthematician, Donald Loveland, to join

us. Dr. IovelandhasbeenmoannendedtousbyGeneIaska.
You
we

will be able to make the 11:00 pm flight if youwish, or
for you to stay over. Please let me know.

can arrange
My

best regards.

Sinceme yours ,
Pink, M.D.
Professor of Psychiatry

Max

MP:kp

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                    <text>E
W

12, 1986

Dr. Peter 1.. Carlton
Rutgers - The State University
Collage of Arts and Sciences
Depw’cment of Psychology
New Brunswick, Na: Jersey 08903
Dear Dr. Carlton:
The CINP aymposiun on

"Anticholirmgic Drugs" will be

published in the series Pangaea in Bud.» Ru and: by
Elaevier Publishing Company, misterdam. The manuscripts

mmbeingeditedanddesigxmtedasbeinginﬂnhmds

ofﬁnpublismbymomxbw
M. Fix-9c.
P. B. Bradley and

31.

meditorswillbe

Ifmmeetthedeadlﬁn,ﬂnpublislwstnpetohaveme

galleyswithinsixweeks.
Thank you for your participation.

Sincerely yours ,
Max

Fink,

H.123.

Professor of Psychiatry

Mf‘ﬂcp

�</text>
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                    <text>December 12 , 1966

Dr. Sheldon

J.

Korchin

University of California
Psyclnlogy Clinic
Edward Chem Tolman Hall
Berkeley, California 914720
Dear Shelly,

‘I'hankyulforﬂﬁmdngofmemgerdmgm. Fazio. Since
to the United States by the New York Medical
knew
of his visit and already had recommended him
I
College,
to my associate, Dr. 'mren Itil.

he was invited

He

gave a lectlme here on friday, but unfortmetely

Immaynameetingandmissedhisvisit.

I

Asyoucantell,weheveretmnedtoﬂew’iwk, whenI
ammvmsestablishingeclinicalmsearchprogramwithinm
activemdicelechoolprogrun. Wheanentto St. Louis, it
was to establish a research laboratory, and this has been
accomplished. The invitation to return East was too good,
despite the fact that the facilities and Opportunities were

mificent.
Dr.
my

‘mankymvezymchfortrdxmofmandIhmthet

Peziohsdapleesentvisitheremdmpethethewillfmd

fomer laboratories interesting.
My

best regards.
Sincerely yours,

,

Fink, MJD.
Professor of Psychiamy

Mex

MPﬂcp

�Decanter 12 , 1966
Dr. Slnldon J. Korohin

University of Califmxia

Paychogy Clinic

Edvard Clues Tolman Hall

Berkeley, California

914720

Dear Shelly,
Thank you

for ﬁﬁnking of ma regarding Dr. Fazio. Since

Mmimited totMlhitodStatesbyﬂuNwYorkMedical
College, Ihmofhisvisitandalmadyhadmoaumndedhim
to my associate, Dr. Timon Itil.
He gave

a lecture here on Friday, but unfortunately I

mmyatametingandmiasedhisvisit.

Asymoantell,mhavemt1mdtoﬁew¥ork,wkm1

mmmatablishingaolinioalmaemhmwithinan
aotivomdioalsohoolpmgrm. mmlmnttoSt. Louis, it
and
Ms been

this
to establish a research laboratory,
The
East
was too good,
invitation
return
to
washed.
and
were
the
facilities
the
fact
that
despite

was

Witios

mifioent.
Dr.
my

'marﬂcywverymmhforthirﬂcﬁxgofmandlhmthat

Fuiohadapleaaantviaitfmrearﬂlnpeﬂnthewillfm
form laboratories interesting.
My best made.
Sincerely yams,
Max

Fink, Md).

Profeam of Psychiatry

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                    <text>December 12, 1966

Dr. Louis Gottsclulk
Department of Psychiatry

thivemity of Cincinnati
Cincinnati 20,

Ohio

_

Dearhou,

Itwasgoodtoheartlntymlmvemviewedthesrmmstgmtefulfaraoopyofymmmport.
tampeyclntinmpypmgxwandaslmentiomd,lwwldbe

‘l'heHalkJnClinicinthisDepartmntMBbemapemtmg
maaixvisitmximmforthepaattmyews. Wommw

involvedinuyingtosetupanevaluationstudyandweumld
begruteﬁxlfwﬁaeowortunitytolearnfrmyowexperierms.
Many

thanks.
Sincerely yours,
ﬂax Pink, M.D.

meessor of Psychiatry

MP:kp

�Y“
.
l
.

:
.

Erna-\mwﬂfr

_‘

‘

.4?
v7,

Deoanber 12 , 1966

'rrmﬁgw/V’m,

-.——u~u

-

Dr. Innis Gattachalk
Department of Psychiatry

Lhﬁvemity of Cincinnati

Cincimnti 20,

Ohio

Dear Lou,

Itwasgoodtohearthatyouhave reviewed the shorttempsychothempypmgzmandaslmntimed,1wmldbe
mostgratefulforaoopyofyammport.
The Walk-In Clinic in this Departmnt has been operating

Weamnow
onasixvisitmathmfortlmpasttmyears.
and we would
evaluation
involved in
be

study
trying to set up an
grateful for the opportunity to learn from your experiences.
Many

thanks.
Sincerely yours ,
Pink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>mm 12,

:Wnru

.z-w

-.
m

1966

Dr.RossAdey

.

Brain Research Inetitute
University of; California Medical Center

Ice Angeles, California

9002»

Dow Ross,

Imttotakemisopportunity,onoeagain,tomﬁ

a
I am now preparing
your presentation. As I mentioned,
dissociationp
121513 and
of
of
the
problem
discussing
report
behavior with anticholimrgio drugs, and it would be met
extensively and aooxmately
helpful if I could
the experimnts you described.

I

wound,

W
More.

be most

grateful for a

the citation) describing the accent to

EEG

and behavior with
Many

LSD.

mm:

mint

thanks.

Pink, M.D.
Professor of Psychiatry

Max

(and

correlations of

Sincerely yours,

Mf'mp

'

.

�Decanter 12, 1966
Dr. Ross Adey
Brain Research

Institute

University of California Medical Center
Los Angeles,

California

9002M

Dear Ross,

I want to take this Opportmity, once again, to cannend
your presentation. As I mnticned, I am now preparing a
report discussing the problan of dissociation of 8% and
behavior with anticholinergic drugs, and
would be most
helpful if I could smmarize extensively and accurately
the experiments you described.

it

I would, therefore, be most grateful for a preprint (and
the citation) describing the mm: to
correlations of

EEG

and behavior with
Many

mt

LSD.

thanks.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

Mf‘ﬂcp

�</text>
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                    <text>Member 12 , 1966
Dr. Peter L. Carltm

- The State University
Arts and Sciences
of
College
Department of Psychology
New Bnmswick, New Jersey 08903
Rutgers

Dear Dr. Carlton:
The CINP

smasiun on "Anticholinergic

Drugs"

will be

published in the series Magma 4n Bub: Raw/Lek by
Elsevier Publishing Company, Amsterdam. The manuscripts

‘

mmwbeingeditedanddesigxmtedesbeinginthehands
‘I'heeditomwillbe
ofﬂrepublisherbynecenbwal.
M.
P. B. Bradley and

Pink.

*

Ifwemeetthedeadline, thewblishersl'aopetohevethe

gelleyswithinsixweeks.
Thank you for your participation.
.

Sincerely yours ,
Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>Daoember 12, 1966

Dr. Lewis Robbins
Medical Director

Hillside Hospital

P. 0. Box 38
Glen Oaks, New York
DearLew,

Sm Meloer was a patient at Hillside in 1953,

who

has

requesting an affidavit. As I recall, she
was admitted with a paranoid psychotic decanpensation and
responded rapidly and well to 'tmatnent.

just written to

me

I believe her request is ﬂammable and would madman:
that an affidavit be provided. If this can be done. through
your office, I would be grateful, or I would be pleased to do

aoiftrnmoordsoouldbemadeavailabletomsothatan

aoexmate

report could be

made.

Sinoemly yours ,
Max

Fink,

M.D.

Professor of Psychiatry

Mchp
co:

m.

Graft

�</text>
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                    <text>Decanter 6, 1966
Dr.

J.

F.

Elsevier

Remus

Rxblishixxg Gummy
P. 0. Box 211
Jan van Galenstrut 335

Amsterdan, the Netherlands
Dear Dr. Remarque:

melosedmtwocopiesofthecontractsignedbyDr.Bmdley

andmyself.

Itavekeptancopyandsmtmtohim.

Thank you

for your cooperation.
Sincerely yours,
Pink, M.D.
Professor of Psychiatry

Max

MP:kp

�</text>
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                    <text>Dumber 6,

1966

m.m1pB.Bxudley

Birmingm,w

DearPhilip,

Wiethsigwdhgxmtwlﬁchisquite
Remarque's letter, Ihave

satisfactory.

1'0ka.

keptomcopyandImwndingtmbacktohim.
Sincerely yours,

Fink, M.D.
Professor of Psychiatry

Max

�</text>
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eiﬂmw'm‘q

\

I

'v

November 29, 1966

mm

Dr. Vincent
Chas. Pfizer and (20., Inc.

Breton, Oomectiout

063140

DearVinoe,

'I'herepor'tmoxmexparienoeswiththiothimhas

for publication in the
Thuapeuuc Rumoh. While the
article does not break significant new ground, I believe
is: of importance in suppour'ting the earlier positive
it
studies.

been accepted by Dr. Severinghaus

January issue of

Many

Cult/Lent

thanks for your cooperation and assistance.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MI-‘:kp

�</text>
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                    <text>m7..——-‘vrv—

4-1"lem-‘IIer':&lt;w.r-v—ernvfn~1.m—.ﬂﬁm

November 29, 1956

any;

Wm:

an

Chairman

of the Editorial Beam
Research Press, Inc.

'

Wutic
520 Fifth Avenue
New

'

York,

New

.
'

York

Dear Dr. Severinghaus:

for your, letterof Novexnben 22, .1986 micatingr
in Schizophrenia" will be
that “Clinical Trial of MothixeneCement
issue
TRpruc' Rea-wok.
the
January
of
published in
Citation No. 7 has been exhumed for publication to the
Thank you

‘

Iowa
be

06 New

listed

Dix/.196

but has not yet been accepted.

as "to be published. "

.

It

should

.

Citation No. ,8, is already in galley and $3th appear in
one of the femoommg issues of Canpaehwiue, Payduéax/Ly.
Since the latest issue of Cmnpmhwéve Paychmay was the
August issue, I would expect this to appear in Volume '7.
Thank yOu for- your consideration.
,

Sincerely yours ,
Fink, M.D.
Professor Of Psychiatry

Max

MFUcp

cc: Dr. 11211

Dr. Simeon

..

‘

�</text>
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                    <text>‘

November 28, 1966

Dr. M. C. Sampson
Vice President for Medical Affairs
Wallace Laboratories
Half Acre Road

W,

Jersey

New

Dear Dr. Smpson:
At the recent

in Washington, a mmber of
investigators referred to studies with tybanate, indicating
that this compound may have potent nuscle relaxant activity
and lesser sedative activity than mpmbwnate. I am writing
to obtain further information regarding the possible use of
this cmpmmd in a study program now mder development at the

'

New

ECDEU meetings

York Medical College.

For the past five years the College has undertaken studies
inﬂue treatment of narcotic addicts. An important element in
the treatment of addiction is withdraWal using methadone. During
the wittxiramal phase, patients complained bitterly of muscle
tension, muscle spasms and cramps. A variety of compounds have
been used with varying success. We are now planning a comparative
study of two suggested treatment methods and in both the
of more effective muscle relaxants during witmrawal may availability
be useful.
~

If the data available suggests that tybamate may indeed be
helpful in such application, I would be grateful for any infometion you can make available to me, and for an opportunity to
discuss this.
‘

Thank you

for your soaperaticn.
Sincerely yours,
Max

Fink,

M.D.

.

Professorcf Psychiatry

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                    <text>ME

'10:

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28, 1986

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                    <text>November 28, 1966‘

Dr. D Papapetropmlos
Allan Menorial Institute
1025 Pine Avenue West

Monml ,
Camda

Quebec

I

Dear Dr. Papapetmpoulos:

Since receiving your letter requeating information regarding
a research and teaching fellowship,- I have inquired as to the
possibility of creating such an appoinment beginning the date
you requested, January 1967. Such positions are planned, but

none are available on

that date.

.

The clinical staff of the
number of raw treatment

ixmtitution is expanding, however,
are established. Each one
requires extensive evaluation.prom
an appointment in the DepartIf
ment of Psychiatr-ﬁ in one of the clinical programs may interest
and

a.

you,

I

would be pleased

Thank you

for

yozm

to process this fwther.
inquiry.
Sincerely yours ,
Kax

Fink, M.D.
Professor of Psychiatry

mzkp

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November 28, 1966

Dr. D. Papapetropoulos

Allan Memorial Institute

:.

www.1-vmn.

1025 Pine Avenue west
Montreal, Quebec
Canada

Dear Dr. PapapetrOpoulos:
“3»erme

Since receiving your

letter requesting information

regarding
a research and teaching fellowshi , I have inquired as to the
possibility of creating such an appointment beginning the date
you requested, January 1967. Such positions are planned, but
none are available on that date.
The clinical staff of the institution is expanding,
however,
and a number of new treatment programs are established. Each one
requires extensive evaluation. If an appointment in the Depart—
ment of Psychiatry in one of the clinical programs may interest
you, I would be pleased to process this fUrther.

Thank you

for your inquiry.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                    <text>‘awwﬁvntxﬂ..v

In-V'

,.

v Wl‘h"'7¢1‘”'ﬂ:lﬂmnr.)’..‘7

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..

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.r~,...-mv.,-.,—w.-~. ww-I‘ N1.

y-m-(wam-«va

:Inavwrnrwv-‘u-fn'v'

Nbvember 28, 1966

Dr. Murray Glusman

N. Y. S. Psychiatric Institute
722 West 168th Street

New

York, New York

Dear Murray,
Enclosed

is

an abstract

for your consideration for the

next meeting of the Society of Biological Psychiatry.
Good

luck in your work and

my

best regards.

Sincerely yams ,
Fink, M.D.
Pbofessor of Psychiatry

Max

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                    <text>November 25. 1966

Dr. Donald M. Shapiro
Washington University
Computer Center

Sever Hall
Lindell and Skinkar Blvd.
‘

St. Louis, Missouri

63130

Dear Don,

_.,,,.A.,_,wr.-

.v...‘

_.
t
.

..

.

V”,

.~

w

--‘.-.

.-.

‘4‘!

A)“.

-.—&lt;-

I have reviewed the graphs and the data which you gave me
of the barbiturate—stimulant EEG study with a View to selecting
the EEG criteria which.may best characterize the drug related
changes. First, I emphasized those variables which had at least
four periods of significant differences of the twenty time
periods studied. After that, I reviewed each of the graphs for
"trends" in order to select additional variables.

It

soon became apparent that on a number of items, the
various drugs could be distinguished at different time periods

identified in the attached table. We have the
drug III and IV, lesser for
greatest number of criteria for
I and II, and least for drug V.
with this table in mind, I would recommend that the discriminant
and theSe are

criteria:

analyses be based onthe fellowing
Items

--

2

and 13 because they are the only ones

fer drug five.

vywwx::tv“‘-'&gt;

Items 3, 5, 10 and 13 because they are detexudnants

2'.-

for a variety of periods

«Ir-yams

and various drugs.

Mam

‘Items

.'137}

11-3

marry-v.

»

&lt;y

-r

“Al-49'“?

Wafer-tap???

a”

a,

Y“.U:L.-!Nv'-m_uw-v

‘2,
_

17

or

18 ~

these

Seem

to

go

in parallel and

is probably satisfactory.
Item u is useful for drug III. There are other‘
determinants at the time periods and this may be

one or the other

deleted.

‘

�Dr. Shapiro

so

-2-

Novenber 25, 1966

While there may be other ways
seems to be the easiest and

far

items be used in the next analysis.

I will call

you

early in the

of selecting criteria, this
I would suggest that these

week.

Many

thanks.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max
1‘1!"sz

cc: Dr.

Itil

Miss Hickman

_

”Ska"

.

.‘
fix—7v

.u.‘

~.—«_,.:rv3r_-v.na—.j..g;7w,,

�</text>
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                    <text>November 22 , 1966

Dr. Charles C. Dahlberg
Research Psychiatrist
Research Department
William Alanscn White Institute
20 West 714th

New

York,

Street

New

York 10023

Dear Clay,

In an introduction, the important designations would
include:
,

Professor of Psychiatry,
1966-

New

York Medical College,

Research Professor of Psychiatry and Director,
Missouri Institute of Psychiatry, St. Louis,
1962—1966

National Institute of Mental Health,
Cannittee on Clinical Drug Evaluation, 1961—1965

Member,

In describing my interests,

been on the

V

t
1,.7

7.

I think my

emphasis has always

relation of changes in brain function

and behavior,
induced
those
by
changes
psychiatric therapies,
especially
including convulsive therapies and psychoactive drugs. With
regard to this symposimn, I have been interested in the neurophysiology of Mllucinogens since 1953 , and haVe studied not only
LSD, but a wide variety of anticlnlinergic hallucinogens in some

detail.

I

.-;:wa.-..a,ow—v1v.—,ty

hope

that

you have

a

few minutes

kind of presentation which would be most

to call

to discuss the
fruitful for the group.
me

1m.“

Sincerely yours ,

:vv

r

Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>November 22 , 1966

Dr. Turan

M.

Itil

Missouri Institute of Psychiatry
SMOO Arsenal Street
St. Louis, Missouri 63139
DearTuran,
Enclosed are xerox copies of two

today. Mirsky's

I

would

asking that

is self-explanatory.

which

I received

like to answer Dr. Cattell affirmatively. He is
provide between $200 and $300 for the publication

we

of this report. Wat

be

letters

do you reocumend?

As you usually say, I hope that each day continues to
better than the day before!

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max
’4
3“

«:T‘f

-:':“’

::
'-:‘"41;"

”win.

.ﬁgﬂnu‘ﬁﬁwlw

5”!"
=;.~

m3:t:=€=:*~"é"*’i"‘:'*“‘.‘t&lt;'-

13W:

57’4"

Mmrzww‘ﬁ‘

W“

k-

141’:an

�</text>
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                    <text>Novenber 22 , 1966

Dr. Athan Karma
558 Harley Drive

Columbus, Ohio u3202

DearDr.Karras:
Dr. Pasananick was kind enough to mooumend your appointment
Deparmuent. At the. present time, the experimental
psychology programs are undergoing their development. You may
know that Dr. E. Roy John has a laboratory at this College and
that many of the experimental neurophysiological approaches with
which his name is associated are now being applied in the clinical

to this

psychiatric pppulation.

Concurrently, I am interested in developing a variety of
experinental psychological tasks in the study of new psycmmpio
compounds in our patient population. In this program, I believe
‘

interested in reaction time measures and in an
attempt to relate them to the changes in the scalp recorded

we would be most

electroencephalogram.

I

_

Pasanania's recummzdation and by
the titles of your publications. If either- of ﬁwssestudy program
mentioned above are of interest to you, I would be glad to process
this further.
am

impressed bytDr.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max
‘

MI-’:kp

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                    <text>Dr. Wazm A.

Missouri

W

Institute of Psychiatry

Arm]. Street
St. Louis, Miami
51400

Novunber 22 , 1966

63139

Dear Women,
Enclosed

is a letter from Addressograph - Mitigmph

Corporation which scans to refer to an old account, since
I have had no contact with than since leaving Missouri.

I have also received
which may interest you.

theemlosedwwandmnfmnﬁﬂw
Sincerely yours ,
Pink, 14.1).
Professor of Psychiatry

Max

MF:kp

�Novanber 22 , 1966

Dr. Warren A. Thompson

Missouri Institute of Psychiatry

Arselul Street
St. Louis, Missouri
SHOO

63139

Dear Warren,
Enclosed is a letter from Addmssograph - Multigrsph
Corporation which seems to refer to an old account, since
I have had no contact with them since leaving Missouri.

I have also received the enclosed murmmn from AGW
which may interest you.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>November 22 , 1966

Dr. Jay Defer
510 East 86th Street
New York, New York 10028
Dear Jay,

a small world and your letter to the Administrator
of the Department of Psychiatry was referred to me for reply.

It is
I

am

pleased that you are interested in coming back to

academic medicine, and
of interest to you.

I think there

may be some

Unfortunately , your curriculum vitae

opportunities

is misplaced

within

I
request that you send me another.
a large file
Would you call my office for an appointment and arrange to
see me at your convenience?
and

would

I look forward to renewing our acquaintance.
Sincerer yours ,
Fink, M.D.
Professor of Psychiau'y

Max

Mszp

�</text>
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                    <text>November 18 , 1966

Dr. Gemld

J.

Sarawak-Former

Cote St. Antoine Road
Montreal 6, Quebec
613

Canada

DearGerry,

I have held your letter of July 13, 1966.311 this time
hoping the CPA] mlement would find its way to me. It

hasn'tandemldbegmtefulifywmuldeendmamﬂmr
copy

to the present address.

I

have recently seen Paul Rajotte. He appears interested

inmtmningtcNewYork.‘ ﬁxewcrkhemhaebeengcingvery
I am excited that we have received excellent support
from the calamity, funding agencies and the established staff.
Ifycuareplaming to attend mofthemeetinge inNewYork

well and

in

December,
My

I

would be pleased

to see

you.

best regaxﬂs.
Sincerely yams,
Pink, M.D.
Professor of

Hex

1!!ka

Wm

�</text>
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                    <text>Novanbw 18 , 1966
Dr. Jonathan 0. Cole, Chief, PRB‘
Barlow Building
5145“ Wisconsin Avenue
Rom 10001

Chevyause, Maryland
Dear

deathan,

Imttoextemmythamcaforﬂnconﬁdenoeﬂutyw

mittees have expressed in supporting the transfer
oftmmmmmwmswymtothism
center. Widens are always diffimlt, and your support
and your

hasmadethismmdaeasierthanlradmpected.
Many

thanks.

Sincerely yams ,
Pink, H.D.
Professor of Psychiatry

Max

'

�</text>
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                    <text>November 18 , 1966

Dr. Karl Rickels
Associate Professor of Psychiatry
University of Pennsylvania School of Medicine
203

Piersol

University

mum
Hospital

'

auoo Spruce Street
Philadelphia, Pexmsylvania 191m

DearKarl,
Jonatkmn called

me

yesterday to

tell me that

the project

rasbeenappmvedbthcunnilarﬂmshouldbeinbusimss

bynextsmmer.

TheAmpexSP—300whichyouhuveorderedisthe'smas

themeIhavemceivcd. Itookthelibertyofcalling

Curtis Engel and checking and incidentally told

to
mmndthe amne‘t‘apeatoyouwhenyoudecidetobuym.
Ilookfmwardtowozkingwithym.
them

Sincerely yours,
Max

Fink,

14.1).

Professor of Psychiatry

MPH-up

�</text>
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                    <text>November 17 , 1966

Dr. Donald M. Shapiro
Washingtm University
Canputer Center
Sever Hall
Linden and Sldnker Blvd.

St. Louis, Missouri

63130

Dear Don,

Jmtmmlecanedmthismmtosayﬂntﬂn

ooumilradappmvedampmyamforfowyeamintm
requested. Heoongmtulagedmmdl-npedthatl
muldenjoy beinginthisbusiness.‘

mt

IhadletsanelocalpeoplelcmtratImslooking

forapzogrwnnermdayomgmn,6ail€leasmr,applied.
Slnisexperienoedmdhasapleasmt personality. She
appoamveryquietandmxdsmofl‘ﬂrm. Igavehera
ooyyoftMmamalandthelSOObooksarﬂtoldhertom
backearlyintheweektotenmwhethershetwm
oouldhandlethejob. Ifsheisintemsted,1wouldlike

rartocallyouforanintmieweitmonthetelepm
ortohavehervisit St. Louis. Iwillcall you early
intheweek.

j

Sincerely yams,
Max

fink,

M.D.

Professor of Psychiatry

�</text>
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                    <text>November 17, .1966

Itil

Dr. Tim M.
Missomd Institutecf Psychiatry

Street
St. Louis, Missouri
suoo Arsenal

63139

Dearmran,
Enclosed are sane odds and ends

foryour inﬂammation,

including a com of the editorial in the J.A.M.A. which you
nothave seen. Enclosedareammberoftear

mmmmmm.
"

receive than.

may

'memprintswillfollmwlunI

Please edittl'eDenberabeu‘actand’retum ittomefor
the Societyof Biological Psychiatry. Ihave sentaoopyto

Dr.DenberasIell. Wmldyoumaleupyow‘I'RPabsmct?
ItavecalledDruBonatoandheissendingthebehavioml
data to the Institute early next

week.

I have spoken to Bill 'I'umer‘mgarding the Dilantin study
and the
am. They are particularly interested in the

We

effect of Dilantin in out-patients, neurotics and psychopathic
states. When I described the adolescent population available
toyou, Bill'rmmrthoughtthiswasvezyinteresting. The

Dilmtinmeetingwillbepartofthemanduilltale place

at 3:00pmonDeoember7. ItisanOpenmoeting, andIbelieve
weshouldplantogo. IaskedBill'I‘tmxertomngeameeting
with the appropriate people after the presentations, if they
were interested in supporting the study which I had described.
Ifyouwishtobringymmslidesandprepareadiswssion, Bill
drought that

it might be useful.

IoanmngefortlnticketsyourequestedifIlcmthe
airlinetobeusedonanypartoftheu'ip.
IhavebeenovertheECDEUmpor'tsandthedissociation
mtwillmedmtimwithboth, pmbablysending
than to you by Monday.
paper,

My

best regards.
Sincerely yours,
Fink, M.D!
Professor of Psychiatry

Max

MF:kp

.

�</text>
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                    <text>Novanber 17 , 1966
Mrs. Nina matheson

Missouri Institute of Psychiatry
SHOO Arsenal Street
St. Louis, Miami 63139

DearNim,

AaIInvemtbeenmoeivingﬂixisjmmul,Ipmm
3. If not ’ please
youhavebeenside-tmckingthcop

write

Wytompmuam.

Sincerely yams,

Pm,
m
Professor of Psychiau'y
MOD.

�</text>
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                    <text>November 16 , 1966

Dr. Herman C. Denber
Manhattan State Hospital
600 East 125th Street
Wards
New

Island

York,

New

York 10035

DearHy,
Enclosed is a suggested abstract for the forthcoming
meeting of the Society of Biological Psychiatry. Turan and
I have gone over some of the data and feel that this would
be an appropriate presentation for that Society. Since the
cannittees are meeting in the first week of December, I am
asking that you edit the abstract, and let me know whether
you would concur in the suhnission.

tapes that are in Missouri ,are being shipped and
should be here within the week.
The

The behavioral data from Ron Bonato has not yet care
to St. Louis. However, I called him yesterday and he
indicated they would be shipped by the end of the week.
Don Shapiro plans to do these analyses on his big computer

Washington University. If this is possible, then the
initial correlations between EEG and beluvioral data should
be available by the first of the year.

at

Paul Rajotte visited us last week. Knowing of the need
for a senior psyclu‘atrist at Coler Hospital, I spoke toA1him of
Freedman.
and when he seemed interested, I suggested he meet
it
When
he
him
Iowenthal.
recommended
to Ir.
Al was delighted and
he
to consider this opportunity. I hope accepts
left us, it was make
possible systematic studies in the aged.
it for it would

�:

m

Jig?

Dr.

Dener

I

-2-

November 16, 1966

have begun some discussions in the Mental Hygiene Clinic

to attempt the development of a clinical drug evaluation unit.
Please

call me about the abstracts.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

111ka

�</text>
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                    <text>November 16 , 1966

National Clearing House for Mental
Health Information
National Institute of Mental Health
Bethesda, Maryland

200114

Gentlemen :

I

would be pleased

to receive a

copy

of the

new

bibliography "Studies on Electroconvulsive Therapy,
1939-1963" which was described in the recent issue of

the PsychOphaImcotagy Bulletin.

Would you also correct my address of record from
the Missouri Institute of Psychiatry to Dr. Max Fink,
Department of Psychiatry, New York Medical College,
5

East 102nd Street,

New

York,

New

York 10029.

Would it be possible to receive an additional
mm
of the Psychophwunacatogg Bulletin, Vol. 3, No. 3, dated
July 1956 for distribution to the Clinical ministry Laboratory
of this

Wt?

Sincerely yours ,
Pink, M.D.
Professor of Psychiatry

Max

111ka

�</text>
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                    <text>N0vember 16, 1966

Dr. Cozan

Elias Publications

P. O. Box 3194
Margate, New Jersey

08M02

Dear Dr. Cozan:
Would it be possible to receive
a copy of the
issue of the Jaunna£ 06 dechOphaMMacology?
Many

initial

thanks.
Sincerély yours,
Fink, M.D.
Professor of Psychiatry

Max

mka

�</text>
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                    <text>November 16, 1966

Dr. Pbrton L. Kurland

Assistant Professor
Department of Psychiatry
New Jersey College of Medicine and Dentistry
2“ Baldwin Avenue

Jersey City,

New

‘

Jersey 073m

Dear Dr. Kurland:

—

In reviewing the proposed announcement of the "Symposium
on Psychedelic Agents ," I can only ask that the title of my
presentation be defined a little more clearly- Would not
"Psychophamxacology of Psychedelic Drugs" be a better description?
more precise
or Dr. Dahlberg favor me by being
Am
wish
I correct in
focus
topresent?
with regard to the
you
wide
of agents
the
wish
enphasize
range
to
assuming that you
of their
the
cmnalities
which have hallucinogenic properties ,
abuse?
of
and
the
problems
central
and
effects,
neurophysiology
LSD
alone?
be
on
Or, is the focus to
Would you

Sincerely yours ,
Fink, M.D,
Professor of Psychiatry

Max

m‘f

‘cc:

kp

Dr. Dahlberg

�</text>
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                    <text>November 16 , 1966

Dr. Albert P. Ax, Editor
Society for PsychophysiOIOgical Re‘search
951 East Lafayette Avenue

Detroit, Michigan

158207

DearAl,
While

I

first two iterns of your request
enclosing
items which may
interest you regarding our data processing ofsome
EEG. For the past
the
few years I have devoted mob of
my interest
the problem of
quantifying EEG changes using digital computertonethods
with specific
reference to the problem of drug response. Much work has
the development of programs and learning the pitfalls in gone into
on-line
processing.‘ I would be pleased to assist you in any way that
we can.
Good luck.
in your

”cannot help you with

letter of

October 31,

I

the

am

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

_

"1ka

�</text>
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                    <text>$.27!

A»;

rar§

w»—

pr

November 16 , 1966
Dr. Donald M. Shapiro
Washington University Computer Center
Sever Hall
Lindell and Skinker Blvds.

St. Louis, Missouri

63130

Dear Don,
Enclosed is a catalog of the College and copies of applications from this Center as prepm'ed by Mr. Carol and one which was
successfully funded from the Downstate Medical Center.
Probably one of the most inportant data processing problems
is that of patient records and their availability for patient
care as individuals go through different units of an institution,
as well as for study purposes. I have just received Monograph No.
from Tulane University which describes their medical information
processing. If you do not have this, and think you wish
I
will send to you. I am enclosing copies of statue of theit,reports
describing the New York University System. Such an application is
specifically of interest to the Department of Psychiatry, but is
surely of importance throughout Metropolitan Hospital and the
Flower and Fifth Avenue Hospitals.
‘

it

Since both institutions are acute medical treatment centers,
applications in relation to laboratory data, administration of
medication, monitoring of acute treatment units, and staff orders
and deployment are all of general importance.
Our interest in physiological analyses ,‘ rating scales and
library applications are probably of less general interest and

should occupy a subservient place in. a general description.

the

day.

I

310?

still going

hope these, notes are helpful. I am
sheets and will send you a note about
_

,

'

Good

’

through

this within a

luck!
Sincerely yours ,
Fink, M.D. :
Professor of Psychiatry

Max

3

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                    <text>D

ii

F
S

E

g

chember 14, 1966
Dr. F. R. Peterson

Bristol Laboratories
Syracuse,

New

York 13201

Dear Dr. Peterson:
There has been a great deal of work on the effects of psycho—
active drugs on the electroencephalogram, and this has included
studies of the antidepressants. EEG patterns differ for each
compound and for each class of compound. These observations,
especially those which have been done quantitatively, have been
useful in defining the clinical range and probable efficacy-9f
new compounds in psychopharmacclogy.
EEG

studies should be

.considered safe for

human

done in man as soon as the drug is
experimentation. If a compound in the

recommended dosage evokes no measurable

index for psychotropic drug efficacy

EEG

effects, the therapeutic

is probably very

low.

If

the EEG changes are still unmeasurable at maximum dosage ranges,
the compound will probably have little clinical merit. If a specific
pattern is evoked in electroencephalograms, the therapeutic index
can be defined with great accuracy.
Optimal methods vary. 'The techniques evolved during the
past decade started with visual descriptions, followed by analog
frequency analysis and analog amplitude analysis, and most
recently have been replaced by digital computer methods. The
present sophisticated techniques make possible accurate delineations
of the probable therapeutic range, if drug studies are dene accurately
and early.
.

While these observations have not yet been considered by the
present FDA as an essential part of a new drug application, the
reports have been of great interest and considerable support to
numerous pharnememﬁical clinical directors, especially those who
have had the opportunity to study quantitative data.

�Dr. Peterson

-2-

November 11;, 1966

A.laboratory for the quantitative evaluation of EEG criteria
being established at this Institution, following my experiences
as Director of the Missouri Institute of Psychiatry from 1962
to 1966.
It will be Operational in the late spring. Such quantitative EEG
evaluations can be undertaken in St. Louis by my associate,
Dr. Turan Itil, who now has the laboratory for clinical e1ectro~
encephalography at the Institute; and alSO by Dr. Carl PfeiffEr
and Dr. Arthur Sugeman at the New Jersey Nam-Psychiatric
Institute.

is

now

If additional data regarding these

interest, I

Street

would suggest you

(212 369—7900)

at

visit the

experiences would be of
at 5 East 102nd

College
your convenience.

_

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
mf:

kp

�</text>
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                    <text>Novanber' 1'4, 1966

4'

"rm”.wvw-IMV‘W‘

»

Dr. Eric Martin, Chairman
Membership Cmmittee

Drug Information Association
12 Bonnybrook Road

Montvale,

New

Jersey

076145

Dear Dr. Martin:
My

w

a

"'.u'uv'|v—

eme'r

hr"

associate,

Dr. Turan

Itil

of St. Louis ,, suggested

that I write directly to you for information regarding the
programs and membership in the drug information association.
I would be grateful for any information regarding the
association that you may make available.

4

Sincerely yours ,
Fink, M. D.
Professor of Psychiatry

Max

mfkp
9:-

71"?)

m

1".‘l'mr‘rw

'&lt;-‘

"
1

--:vm&lt;'“m

,

�</text>
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                    <text>November

11¢

, 1966

Dr. Allan F.
Division of Psychiatry
Boston University School of Medicine
Boston, Massachusetts

DearDr'. Mirsky:

Sammthsagoyouwemkindemughtoserﬂapmprint

of your report "The Relation of EEG and Performance in Altered
States of Conscioumess" to my associate, Dr. Itil. The pre-

print is

oo—euthored by Eva Pragay.

are preparing a final draft of‘ourreport on the
dissociation of EEG and behavior with anticholinergic drugs
which was presented at the 1965 meeting of the American EEG
Society, and would be pleased to quote your report. Can you
tell me where this is being published? The copy we have is
undated but has 16 pages of text, two pages of legends, six
pages of citations and eight figures. I hope this infoma‘tion
identifies the manuscrip .
We

’

Many

'

thanks for your assistame.
Sincerely yours,
Max Fixak, M.D.

Professor of Psychiatry

1“ko

�</text>
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                    <text>November 11, 1966

Dr. Samuel Lel'mnan, Director
Department of Psychiatry
Long; Island Jewish Hospital

New Hyde

Park,

New

York

Dear Sam,
Thank you very much

If it is

for the inquiries which you

made.

without special effort on your part, I would be

pleased to rejoin the

staff.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>‘1'

'l-rnﬁww’h‘ﬂ'“

a"

:'rv’,’.ﬂ-’Aq""‘ﬂ."'

November 9, 1966

Dr. Edgar M. Flint
Geigy Plumaoeuticals

Ardsley,

New

York 10502

Dear Ed,
Thank you very niuch for the Lehmann-Rockliff Rating Scale
for depression. It seems simple enough and may be even easier
to use than the Zung.
As soon

as

I

to try this in a

it.

adopt

have

few

this depressive study organized, I intend
and if satisfactory, will probably

subjects

‘

The organization of the out~patient evaluation unit is
coming along, though slowly. The first study will be implemented
by January 1, and I hope to be able to undertake others soon

thereafter.
My

'

best regards.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

’1!ka

�</text>
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                    <text>November 9, 1966
Dr. Werner P. Koella

Senior Scientist

The Worcester Foundation

Shrewsbu'y, Massachusetts 01545

Dear Werner ,

for your kind invitation to participate in the
meetings. I will do my best to prepare a manuscript and
hope to have it available at the time of the meeting. I am
going over the data now with my associates in St. Louis and
do not think that I will have the manuscript available until

ACNP

Thank you

December 1.

Incidentally, much of what we present may be more appropriate
as discussion or immediately following Dr. Martin's presentation,
since I believe the two discussions are more closely related.
Sincerely yours ,
Pink, M.D.
Peofessor of Psychiatry

Max
gm,”

.e

w"...

for Experimental Biology

111ka

�</text>
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                    <text>Novmnber 9 , 1966

Dr. Richard Abrams
10“ Childress

Sheppard AFB, Texas 76311

DearDr. Abrams:

aftermon of Friday, December 2, would be the best
for
I will be attending the meetings of the ARNMD at
Roosevelt and these may be of interest to you as
Hotel
the
The
afternoon session interests me least and I would
well.
be pleased to meet with you at 2:30pm at the registration desk.
Ifyouwill inquire formeat that time, Iwillbe inthe
The

me.

immediate neighborhood.

my

I

If there is

office

am.

any problem about finding me, please

369-7900 Ext. 2“? and my

The Hotel Roosevelt

is

secretary will

on Madison Avenue and “Sth

I look forward to meeting with

call

know where

Street.

you.

Sincerely yours ,

n
E

avg—my,”

Fink, M.D.
Professor of Psychiatry

Max
.4.——.,-n4.uwu‘

vI-r‘m

&lt;

mfkp'

'

�</text>
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                    <text>November 9 , 1966

Dr. Philip B. Bradley

Meal

The
School
Birmingham 15, England
Dear

Thank you very much for your letter of November .3. The
draft agreement is satisfactory.
You are to be camerﬁed in
negotiating this instrument .

I recognized that the

'-'-'

“I

.rrzm""

required some work but
felt it was more important manuscripts
to send them on to you at the time.
If you wish to send any back to me for my editing, I will be

glad to do what I can.

1w

I

checked in

the figures of

Your letter to
will respond.
My

my

.
_

files

and did not find the legends for
nor can I recall having seen them.
sufficiently explicit and I am sure he

Voj teohovsky,

him

is

'-

best regards .
Sincerely yours ,
Fink, M .D.
Professor of Psychiatry
Max

mfkp

Vrgpavrra'

’

'

37‘

AV

»~:

-

Philip,

‘

“y“,

’
‘
.i

"W"""’"“"”v“&lt;

W12."

Warmeat'ws»mrnqur

�</text>
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                    <text>November 9 , 1966

Dr. Milos Voj techovsky
Institute of Pharmacology
Medical Faculty of Hygiene

Charles University

Praha lO Vinohrady, Srobarova 50
Czechoslovakia
—

Dear Milos ,

for your letter of October 19. I had a very
pleasant meeting with Dr. Vinar in Madrid and I think it was
a well run session.
Thank you

No, I did not receive samples of l— and dl-cycloserine
which you describe as leaving Prague in August. If these had
been received in Missouri, I am sure that my aseciates would
have sent it on to me. However, I will be in St. Louis at the
end of the week, and I will specifically inquire as to whether
such a package had been received.

Dr. Simeon
hope to be able

is

moving

to

to Undertake

New

some

York

early in January

and we

joint studies soon thereafter.

I have just received a letter from Dr. Bradley indicating
that the legends for the figures for your paper in the symposium
"Anticholinergic Drugs and Brain Function in Animals and Men"
were missing. I reread my copy of your paper and see that you
have included the figures without a description, assuming that
the text describes each figure accurately enough. It would be
helpful if you would provide legends for each figure separately,
and send these directly to Dr. Bradley.
As I told you in Washington, I am unhappy that I have not
renewed many of my subscriptions for journals, since in Missouri
almost all the journals for the library came first to me. I am
now establishing some other subscriptions. In the meantime, I
have asked try secretary to send you each of the journals that I
receive, except for the EDS journal which I wish to keep.

�,,._

y~.«..-.

.,

was.»

r'r‘r-vvx'

.4.

Dr. Vojtechovsky

November 9, 1966

-2-—

In an earlier letter you were kind enough to invite me to
to Europe in January. I do not think this is possible as
I am in the midst of a new program and what seems delightful and
possible in the early sunmer becomes very difficult six months
later. But, many thanks again for your kind invitation.
come

Again,
Washington.

my

thanks for your participation in the meetings in
best regards.

My

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

mm

�</text>
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                    <text>November 7, 1966

Research Director

Searle

G. A.

P. 0. Box 5110
Chicago, Illinois 60680

Dear Sir:
Dr.

in the

AubreyGoodmanhasbroughthiszeportonlanotil

treatment of narcotic withdrawal to our attention.
This laboratory is specifically interested in the treatment
of addicts, and we would be grateful for capies of such
general reports as may be available, as well as citations

to reports in. the litmtm'e.’
Is thelND'still active, and have any other reports
of its use in narcotic addiction been published?
Sincerely yours,

Pink, M.D.
Professor of Psychiatry

Max
‘

1“ka

�</text>
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                    <text>November 7 , 1966
Dr. John C. Kramer, Chief
Research Department
Department of Corrections

California Rehabilitation Center
P. 0. Box 8'41
Corona, California

Dear John,
Your

letter of

I hepe I gave

you

October 31, was received

the information

is a

this Homing.

you (asked on

the telephone.

of the program of the ARNMD and
relevant-pages from a recent bulletin of the ACNP. These
should be sufficient justification for your visit to New York.
Enclosed

When

copy

you have your program

outlined

and

let

me know

whenymwillbeinNewYom, Iwillmaketheneuessary
arrangements for your visit to this center.
My

best regards.
Sincerely yours ,

mx Pink,

MOD.

Professor of Psychiatry

111ka

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                    <text>m

First National City

Park Avenue
399 Park Avenue
New York, New York

Bank

W

7, 1966

Gentleman:

Please deposit the enclosed contribution to the Memorial
Scholarship Fund for I)". R. P. Bircher at the Columbia
University, College of mysiciens and

Sm.

Sincerely yams ,
Pink, 14.1).
Professor of Psydmiatry

Max

mfkp

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                    <text>Novmber
Dr. Henry

7,

1966

Brill

Pilgrim State Hospital
Brentwood, L.I.

,.

New

York

Dear Henry,
week.

Imsm'r'ytlatwewemmabletogettogeﬂxerlaat
We
are going ahead with a provisional protocol

ammilethmearemxyquestions,perhepewewillhave.
a chance to discuss them smietine in the future.

muﬂemnivisitedwithustodey.
muchforsendinghimtous.
My

Wywvery

best regards.
'

Sincerely yours,
MmcFink, Md).

Professor of Psychiatry

mka

�</text>
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                    <text>November n, 1966

Dr.

J.

C. Holden

M.

Missouri Institute of Psychiatry
51400 Arsenal Street
St. Louis, Missouri 63139
Dear'Mike,

It has

taken me scmetime to review the laboratory report.
subject is a most inportant one, and especially with the
recent articles which you have read. The major criticism that
I have of the paper is the lack of focus. The introduction is
dedicated to the general problen of laboratory standards, much
as our previous report. The discussion exercises some theoretical
The

aspects of the laboratory test changes, and the methods and

results are a staple statement of some of the changes observed
inourprogem. Ifthereportistobefocussedonlaboretory

data, then the discussion should follow

some

of the similar

aspectsofoxmpreviousreportandperhapsexpomdmfully
on the significance of laboratory tests in the treatment of the

mentally

ill.

Butthiswouldbetoomk. Ifthefocusweretobeon

the significance of laboratory test changes as indices of
physiological effects of these compounds, as seensto have been
the focus in some of the recent reports,,then this document is
deficient in not annotating the other reports more fully.
With

this in mind, I

would suggest

a concentrated review

ofthelitenatmeofthelasttmyear’sontheassociationof

pl'xemthiazineswithsuddendeaths, Newcardiacehanges,
effectsonthevisual systemandonthe skin. Bysumnarizing
these valuable reports, I think you will be presenting a
succinct picture of a major problem. After that introduction,

traspecificaspectsofthedatawhichmfindmmsualinum
long term study patients, can be presented within the context
that perhaps the small changes are still of significance.
My

oaments regarding the present discussion are largely

related tothefact that Idonotthinkweare inagoodposition
to discuss theoretical aspects of clinical physiology from our
vantage point of psychiatry.

I trust these consents are helpful.

My

best regards.

Sincerely yours ,
Pink, M.D.
Professor of Psychiatry

Max

Inf 19

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                    <text>Novanber H, 1966

Dr. Stewart H. Frazier
Chairman, Program Ounnittee
P. O. Box 200%
Houston, Texas 77025
Dear Dr. Frazier:

associates and I would like to prepare a demonstration
for the forthcaning Detroit meeting of the American Psychiatric
Association entitled, "Applicatim of Digital Computer Analyses
of the EEG to Psychiatry." For this demnstratim, we would
like to emphasise the procedures developed during the past few
years for the classification of EEG signals and some of the
applications to psychopharmaoology and clinical psychiatry.
The core of the danonstration will be tape recordings of EEG
signals analyzed in real time, utilizing an IBM 1800 system.
For this purpose, floor space of approximately 12' x “0'
would be required.
I trust that this meets with your comnittee's approval.
My

Sincerely yours ,
Max

Firm, M.D.

Professor of Psychiatry

nIka

�</text>
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                    <text>November 2 , 1966

Dr. Jovan Simeon

Missouri Institute of Psychiatry
51500 Arsenal Street
St. Louis, Missouri 63139
Dear Jovan,

thiothixene paper has men sent to Current Thergpeutic
Research, with your corrections. Xerox copies for you, Ali,
and Turan are being sent separately for you to distribute.
Ponce
The

I have discussed your appointment with the administration.
Since you should cane on a full-time basis, I have asked for a
higher than usual salary (almost everyone is also in practice)

andthishas causedsomeooncern. IwillcallywonPridayin

any case.

it

closerine:

The summary of 10/26

is incomplete, insofar as

does not give the dates and "results" of subsequent treatments.

1. For each
and evaluation.

Itil

patient, what dosage did they have, dates

to emphasize the relation of blood
level to symptom or symptom relief. Would you identify for each
patient three periods according to their blood levels: zero to
MS mgn‘b; us—as Inga;
greater than 65 mgm‘t. 'I'henexamine the
psychopathology scores for affect/mood/ emotion; motor; and
2.

Dr.

wants

oonsciousness/orientation/highermental function. The question:
is there a relation between blood level and the change in these
symptoms?

Prolixin: ok
CyCIazocine: ok
My

best regards.
Sinoemly yours ,
Pink, M.D.
Professor of Psychiatry

Max

mfkp

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                    <text>November 2, 1966

Current Therapeutic Research
Editorial Office
520

New

Fifth Avenue

York,

New

York

Dear Sir:

associates and I are pleased to submit the enclosed
"Clinical
Trial of Ihiothixene in SchizoPhrenia" for
report
your consideration for publication in Current Therapeutic
My

Research.

I

am

,
,

enclosing an original and a xerox copy for the use

of your editors .,

Thank you very much

for your consideration.

A

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

111ka

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                    <text>Novanber

Dr. Paul Rajotte
Institut de Recherches Psychiatriques de

Hopital Saint Charles
1000 Bwlevard Ste. Anne
'

Joliette,
Canada

l,

1966'

Jolictte

Quebec

'

DearDr.Rajotte:

Itwouldbeapleasmtoluveyouvisitwithusif

youareavailableanydayofthemekochvanber7crlu,
excaptNovenberllandls.

'I'hebesttimfcrmisanyaftmfsz:00pnon.

Iwillalsommgeforyoutomttlnﬂmimlmoftm

Departnent.
Ext.

If you wish to
2'45.

My

confirm this, please

best mgardsr

call

(212) 369-7900

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

mfkp

�</text>
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                    <text>~v...7,_..ﬂ,.. 7.,

v-nrr-u'w

Wu‘.'wvv»‘ihw"i www- rtrru—a—v WI""W’~V‘

..

v.”--

,

To

WH’WI-v-m'

.—

u—w—V-

”WW,“—

Myra—A

._

October 31, 1968

- Who's Who
201 East Ohio

Marquis

Chicago,

Gentleman:

I leave just moeived the Tenth Edition of Who's Who in
Midwest. Effective July 1, I have relocated to New
and would be pleased to have the next entry included in the
volume marked "Who's Who in the East."

m

the

mum:

av,

.uwm

.4

u

-

v

‘rrrr‘wwmv

'T—m-‘Yl"

-«
w
;.

v—mr-nr-

wryPlrr-K

is

is

Great Neck,
102nd

Fink, M.D.
Professor of Psychiatry

Max

~

«:w

new

Sincerely yours ,

(2'

WW

address for

39 Arleigh Road,
my ham
New
York
5 East
11021
and
Island,
my office
New York, New York 10029.
My

Long

.w

'-’n“yo'

Illinois

1!!ka

Street,

�</text>
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                    <text>FEW

October 31, 1966
Dr.

550

New

Julius Korein
First Avenue
York,

New

York

Dear Dr. Korein:

.

......_-

"m...—

Dr. Freedman and I would be pleased to have you discuss
a presentation of "Computers in Psychiatry," which I am
presenting at the weekly Department of Psychiatry Staff
Meeting on Friday, Novanber 25. The meetings are from 12:15pm
to 1:30pm on the fifteenth floor, conference hall, at

Metropolitan Hospital.

.
_‘

Enclosed

is a

copy

of a short discussion which I recently
My presentation will

prepared for Dr. Preedman' s textbook.
follow this text rather closely.

I have read your papers with interest, and after speaking
of your favorite moters , I am even more interested to
visit with you. We can arrange it for some day after this
presentation. Perhaps you would also be interested in a discussion
which I recently prepared for a symposium of the World Congress
to

one

which

illustrates

Many

one of these appl'nations , and

this is enclosed.

thanks.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

Inf kp

cc Dr.A.M.Iraedman

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                    <text>I'm

October 31, 1966
Mrs. Darlene R. Wilson
Box 68

Crozet, Virginia

Dear Mrs . Wilson:

for your letter of October 20. I am establishing
laboratory and m1fortunate1y cannot get Grass equipment
until early March. I had hoped to be able to begin work in
December, but find now that delivery schedules have been delayed.
The laboratory is being established at Metropolitan Hospital.
I am enclosing a 00py of a report which I recently read, which
may give you a better idea of my interests.
Since this is a new laboratory in the Department, we do not
have specific personnel policies other than those of the College.
If you can be available March 1, I would like to know your present
salary and what differential you would wish to relocate in New York.
'

a

Thank you

new

'

Inﬂmeeventthatyouareplanningtocmmetotheﬁastemﬁm
I would be pleased to meet with

Meetings at the end of Novanber,
you in any case.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

mka

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                    <text>F

i
g

October 31 , 1966

i
3
§
E

g

Mr. Robert C. Zwahlen

Mical

g
t.
g

i
,

i

E

if

Liaison Staff
Clinical Investigation Department
Smith mine and Premh Laboratories
1500 Spring Garden Street
Philadelphia, Pennsylvania 19101

E

Dear Bob,

7

l

I

..

first analyses

of the EEG changes. at twelve minute
intervals , using variables demonstrates significant
differences amng the oonpomds at various times. We are
now ready to plot these variables and to select those that
appear to be the most discrimimtive.
The

17

.

I

am

W

heartenedeby this finding, because

it means that we

in the data,
probably have significant discrim'nation
although at this point I cannot tell you which from which. The
plotting should be done within the week and the necessary analyses
will be undertaken on November 11, when I go to St. Louis.
My

best regards.

_

Sincerely yours,
Pink, M.D.
Professor of Psychiatry

Me):

mka

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                    <text>October 31, 1966
Dr. B. L. Martz, Secretary
The American College of Clinical Phannaoology
and Chemotherapy
230 Nerth Broad Street
Philadelphia, Pennsylvania 19102
Dear Dr. Martz:

It is

for your kind letter of October 25.
a pleasure to join the American College of Clinical

Thank you very much

Pharmacology and Chemotherapy.

Please be advised that as of July 1 I left the University
and am now Professor of Psychiatry
the New Ycrk
Medical College. my new address is 5 East 102ndat
Street,

of Missouri

New

Ybrk,

New

York 10029.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

13ka

�</text>
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                    <text>October 31, 1966

Peterson
Sales
Instrumnt
Grass Instrmnent Oanpany
Quincy, Massachusetts

Mr. Robert A.

.

Dear Mr. Peterson:

letter of October 22, makes me very sad indeed. In
with you and Mrs. Grass I was told that
discussions
my prior
the approximate delivery date was five mouths.
Your

.

formal order was sent on August 20. Because ‘of initial
conditional requirements in the Department, I called Mrs. Grass
and told her that this order was fully supported by me personally.
As I told her in Denver, the conditional nature of this order
has been removed. A formal note to this effect is now being
A

processed by the College.

In moving from St. Louis to New York, I brought no equipment
with me. I am anxious to get these projects started and have no
other amplifiers to substitute. For this reason, delivery in
late March will mean that productive studies will have been
deferred for more than nine months. I can only request that
to the extent that you can, that you attempt to adhere to the
The Grass Instrment Company has
always had my understanding and this letter represents the

original time schedule.
second

tine in our relationship that I have asked yours.
Sincerely yours ,

hex/rim,

M.D.

Professor of Psychiatry

“1ka

�</text>
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                    <text>October 31 , 1966
U. S. Naval

San Diego,

Hospital

California

92131}

Dear Mr. KOpenski:
Enclosed is a statement which I read at a recent meeting
in Madrid, which gives you some“ idea of what we have tried to
do.

laboratory to accomplish this mission is being established.
EEG equipment and unfortunately, the delivery
The canputer equipment should be delivered
March.
date is early
We
in the early summer.
are planning two laboratories, one in an
out-patient facility and one at the Metropolitan Hospital for
A

We

have ordered Grass

in-patients.

are those of the Department of Psychiatry
laboratory in the Department, we
have not yet established any special policies. The working hours
will probablybeanﬁnimnnof fortyhowsperweek. Asilaryrange
is yet to be established._ I would be interested in lowing what
your present salary is andwhat you would be interested in receiving.
The personnel policies
and since this is the first

EEG

You can probably get more information regarding the
and interests of this laboratory by discussion with Dr. LaVerne
Johnson.

I

would be pleased

a statement of the time
salary.

to receive a copy of your curriculum vitae,

when you may be

available, and the requested

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

mfkp

�</text>
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                    <text>-

—v,

October 28 , 1966

,.

«t

-._.w_....-..W—.r'.—www~..er

Dr. Turan

M.

Itil

Missouri Institute of Psychiatry
5400 Arsenal Street
St. Louis, Missouri 63139
.

Dear 'Iuran,
Enclosed is the manuscript of the delirium paper with the
corrected references. Not only did we correct those marked by
the editor, but there were two or three additional ones that
were no longer in press. We have corrected the text to show
the new reference numbers. Rather than increasing the number
of errors by ‘retyping the whole text, I believe it is sufficiently
clean with the corrections to be easily handled by an editor.
Secondly, I am enclosing a final copy of the digital computer
paper which has been submitted to Drs. Kline and Laska. The
proper citation is as indicated in No. 20 of the list of references
in the delirium paper.
EEG

-

Don and

I went over the

SKF

material. There are

numerous

criteria which distinguish drug effects! Cong'atulations! The
next step is to graph some of the present data and then to select
those criteria which are most general. If these make sense to us,

will then carry out a discriminant function analysis for three
sub-groups: barbiturates and placebo; stimulants and placebo;
barbiturates and stixmilants.

we

I

am making arrangements

Saturday, November 11 and 12.

to visit with

you on Friday and

to Jovan, with whom I spoke Wednesday afternoon,
arranging for the Chairman to write him a letter of appointment and if this is satisfactory to him, he should feel free to
discuss it with you and Warren.

I

am

With regard

In discussing the APA demonstration, Don felt that it would
take twomonths topreparetheprogrens. Iwouldlike tomake
the demonstration especially, if NIH approves the present applica—
tion; waver, I would like to do nothing until after November 20
and if I get a positive reply, will then ask Don to reprogram at
Washington University. He tells me that he will not use the NIP
staff and that this programming will not interfere with the MIP
operations. However, I believe that a most inwtant demonstration

�Dr.

Itil

October 28, 1966

~2—

be the classification of sleep stages and would like to spend
with you on this problem dwing my next visit. With
time
some
regard to support for the denmnstration, I believe it will probably

mild

cost $5,000 for progranming, $3,000 for incidental expenses like
personnel to attend
printing and artistry and a minimum of $1,500 for
be obtained from
could
of
some
this
Detroit.
If
demonstration
in
the
prmnaoeutical concern without interfering with any of our other
relationships, it would be helpful.
Finally, I am sending you the micaﬂﬂvitae of Dr. Andre J.
Angyan. He is a personable Htmgarian with considerable experience
in nemophysiology. If there is a place for him in your program,
I am sure he would be willing to visit with you.
mclosed is a short abstract for the ASMP. Please correct it
and send
My

it on.

best regards .
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

111ka

�</text>
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                    <text>October-28, 1966
Dr. Tman

Itil

M.

Hissomi Institute of Psychiatry
5400 Arsenal Street
St. Louis, Missouri 63139
‘

Dear Turen,
Enclosed is the galley proof for Ccmprehensive Psydﬁatry.
I have read the text and found very few errors.
For reprints, please order 100 with covers for me. I
wouldsuggestywcallDr. Taborandorderasmanyashe.
wishes, in addition to those for Ali and yourself.
Add
47.....-

«

Under authors

yams and
Again,

V

identification, Kathy has typed in

Ali's.

my

my own.

best regards.

37—10”

Sincerely yours ,
‘Wndlﬁo‘niwyﬂhr-P}

a—v

Fink, M.D.
Professor of Psychiatry

Max

m—

'."P\.

x
n

wvaz-w:wav=v‘

rrrrv

“w-W-

”1ka

�</text>
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                    <text>October 28, 1966
Mr. Robert A. Peterson

Instnnnent Sales

Grass Instrument Oouapany
Quincy, Massachusetts
Dear W. Peterson:
Your

letter of

October 22, makes

very
prior discussions with you and Mrs. Grass
the appmdmate delivery date was five months.I

my

me

sad indeed. In
was

told that

Afomalomderwas senton
20. Because of initial
conditional requirements intheDepartment, Icalled Mrs.
Grass

andtoldherthstthisomderwasfullysupportedbymepersonall.

AsItoldherinDenver,thsoonditionalnatheofthisorder
hasbeenremoved.

Afomalmtetothiseffeotisnwbeing

prooessedbytheOollege.
In moving from St. Louis to New York,
no equipment
withme. IanamimstogetthesepmjectsI brought
startedandhavem
other amplifiers to substitute. For this reason, delivery in
late March will mean that productive studies will have been

defmed formthanninsmonths. I canonlyrequest that
tothsextentthatyouoan,thatyov.1attempttoad1m~etothe

original time schedule. The Grass Instrument Company has
always had my understanding and this letter represents the
second time in our relationship that I have asked
yours.

‘

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

"‘ka

.

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                    <text>v-7“

”rm-5,

'F‘W‘ﬁf—Ir‘rw—wa“

v

it
E

:E

i.

OCtober '28 , 1966
'

m.

R. W.

Stacy

Dept. of Surgery, UNC Medical School
N. C. Mencrial Hospital
Chapel Hill, North Carolina

Dear Dr. Stacy:
Thank you very much

for the kind invitation of the

organizing group to join the Society of Biomedical Canputing.

In my work at Washington University during the past few
years, I found that many members of their staff were extremely
helpful. Dr. Donald M. Shapiro, Assistant Director of
.

Washington University Information Processing Center in charge
of Project Services, Sever Hall, Lindel'l and Skinker,
St. Louis, Missouri 63130, has been actively involved in

‘thiemrkwithmeandeculdliletcsuggestthathebe
invited
to participate in the formation of this society.

I believe his contributions could be of considerable interest.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

,

mfkp‘

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                    <text>October 28 , 1966
Miss Constance Virginia Hichmn
Couputer Center
Missmmi Dustitute of Psychiatry
51500

Arsenal Street

St. louis,

Miami

»

-

63139

DearCormie,‘
mom.

Kathytoldmofthetapeproblem. Iheartilyexpeoted
Idomthaveamthergoodtapetosendyou. Iam

makingmangmmntstobeinSt.LouisonNovemberllarx112,
andmuldmébepleasedifloouldgooverwhateverywhaveat
thatt .
brought the barbiturate study material and this
seened very good. He has some suggestions as to the next
Don

stepandpmbablyhasalreadydisoussedthiswithyou.
WemtinWasMngtontogoovertheDenbernaterialam
wehaveaskedDr. Bomtotosendsomeofthebehavioraldata
to St. Louis, When it arrives it will be in card format and
thesamekindofanalysisthatwasdone fortheEBGsauples
will probably be done for this data; weaver, it would be
helpful to see a listing and perhaps a simple print-out should

first be prepared.

firal draft of our presentation
like "aannie" better than "Constance" "
until you authorize otherwise, it will remain as "Constance.
Homver,youwill stillhaveachanoetodmangeit, asIexpect
Enclosed

in Madrid.

is a

copy of the

While you

the galley proofs in a

few months.

I look forward to seeing

regards.

you

in mid-November.

My

best

Sincerely yours ,

Pm M.
m
Professor of Psychiatry
’

mfkp
P.S. Aseoondoopyésenclosddfor Don.

D0

�</text>
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                    <text>October 27 , 1966
Dr. Eugene Laska
Rockland State Hospital
Orangeburg, New York
Dear Rene,
Enclosed are prints and legends for our report
"Digital Computer EEG Analysis in Peydmopharmacology. "
On some of the prints I have the negatives, and
if the
printer prefers getting those, Iwould be glad to make
than available.

IwillcallyouaboutNovember7,andhopetosee
ywsoonthereafter, Mybest regards.
'4t'v

Sincerely yours ,

av"

.—,-

w,

p.

Fwy—q

war-«v

.4

‘:m',

v

awn.—

v-r'n-v’.

'

Max

rink,

M.D.

Professor of Psychiatry
MF:)q&gt;

�</text>
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                    <text>October 26, 1966
Dr. Richard Abram
1014

Children

Shepherd Air Force Base, Texas 73611
Dear Dr. Abrams:
Dr. Madman has

sent

me

your

lettw of

October

11+.

Iwwldbepleasedtohaveywvisitdnmingyoxmnext

trip East. If you will call my secretary or write, I

would be pleased

to set

up

a definite appointment.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>“

mm;.\

q-w.

W

‘..1—

”wax”,

-_..

October 26 , 1966
Dr. Leo G. Abood, Professor
The University of Rochester
River Canpus Station
Rochester, New York 114627

Dear Leo,

thanks for your letter of October 17. While I would
be pleased to recommend Bernie, I am in the difficult position
of his never having worked directly with me, so that I am
acquainted with his professional competence secondarily.
Many

As you know, Sam recon-ended

his initial

work

an independent

his appointment and supervised

in St. louis. After

role.

Sam

left,

Perhaps we can get together in Puerto Rico.

regards.

Bernie assuned
My

best

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

mka

�</text>
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                    <text>October

21+,

1966

Dr. John Laidlaw

Medicil Research Council
EEG Unit
Western General Hospital
Edinbm‘gh, Scotland
DearDr. Laidlaw:

recent Proceedings of the HEB Society of October 30,
indicated your continued interest in quantitative measures of
EEG. I recall your applications to changes with liver disease
and would be grateful for any preprints which you may have
available for other clinical applications. Your suggestion
that the MDF is most sensitive in clinical correlation is of
interest. In which studies in addition to the cardiac operations
has this been true?
‘I'he

Msnytlmnks.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Mex

MF:kp

�</text>
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                    <text>October 21, 1966
Dr. Samuel Lehman
Director, Department of Psyclﬁatxy
Long

Island Jewish Hospital

Glen Oaks,
Dear Dr.

is a

New

York

term:

It was a pleasure

copy of

my

talking to

curriculmn vitae.

you yesterday.

Enclosed

mny thanks foryour time.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

“1ka

�</text>
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                    <text>October 20 , 1956
Dr. Joseph Bird
Staling—Wintlmap Research

Rensselaer,

New

York 1211“;

Institute

Dearth Bird:
Enclosed

I trust

My

it is

is the statement of irwestigator‘ you requested.

satisfactory.

best regards.
Sincerely yours,
Pink, M.D.
Professor of Psychiatry

Max

Ifzkp

�</text>
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                    <text>October 20, 1966
Dr. Jonathan 0. Cole

National Bank Building
6917 Arlington Road

Bethesda, Maryland 200ll+

Dear Jonathan,

gives Dr. Itil and myself great pleasure to enclose
summary statement of the studies which have been undertaken at the Missouri Institute of Psychiatry during the past
eighteen months.

It

a short

As you know, not only are these studies clinical in mture,
but for most of them, the EEG and clinical laboratory data have
received Special attention. The report on trifluperidol is'
published and those on thiothixene and fluphenazine decanOate,
cycloserine, butaperazine and metronidazole are all in various
stages , with our expectation that they will be completed by the

end of the year.

thioridazine , chlordiazepoxide and combined
has been completed and the behavioral data analyzed. The
data is now being analyzed and when that is oanpleted, the
reports will be prepared.
C and
EEG

The study comparing
T

During the past few months in Missouri, studies on netronidazole,
(comparison with perphenazine), cyclazocine in depression,
and dilantin and thioridazine in adolescent behavior disorders have
been in progress. 'Ihese studies are under Dr. Itil's direct superP—5277

vision and responsibility. Part of the financial support of these
studies is caning from MH~ll$80 and 11381.
In New York, in part with the support of MH-12567, we are
studying cyclazocine in the treatrent of narcotic addition and
comparing it to methadone maintenance in the treatment of depressives.
These are clinical studies , although it is my hope that an EEG
laboratory will be established during the next few months.
Many thanks for your support and
continued collaboration.

we

look forward

Sincerely yours ,
Max

Fink,

mm M.

11:11, M.D.
'

mf kp

M.D.

to our

�</text>
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                    <text>October 18, 1966

m. Jovan

Simeon

Missouri Institute of Psychiatry
suoo Arsenal Street
St. Louis, Missoxmi 63139
Dear Jovan,

is a

copy of the thiothixene paper which I
have attracted. Please edit this and return it. Ivhave
kept the original and will have Kathy correct
Enclosed

itfor

Wﬂmepeuticlieseamhifywappmve. 'I'hereazea
few

questions. I am also enclosing an earlier copy of the
thiothixom report for you to see what was omitted or
.

changed.

'

.

PleasecheckTableIandtellmswhat toputinfor

to 15 under results. On page nine, the first
four sentences give a vague statement about EKG results.
This should either be expanded to something meaningful

patients

13

or deleted. Please
Enclosed

recommend.

is your copy of the clinical laboratories paper

asitwassenttotheJoxmalofNewm.
Ali has.
fluphenazinev
capy

Kathy sends

that

Pleasedxeckthe

best regards.
Sincerely yours ,
Pink, M.D.
Professor of Psychiatry

Max

1“ka

�</text>
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              <elementText elementTextId="25162">
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                    <text>October 17 , 1966
Dr. Joel Bikes
Henry Phipps Professor of Psychiatry
Director, Department of Psychiatry and

Behavioral Sciences

Tne Johns Hopkins University School
The Johns ibpkins Hospital
Baltimore, Maryland 21205

Dear

of Medicine

Joel,

Itweswithaheendisappoinmztthetlmfrm

Dr.Cluffthetyouwou1dmtbeabletoclnzrthesession

mt‘ridayatNIAID. Wewillallmissyou,and1especia11y,
emcelwaslookingfomm'dtomtherdiscussionasetthe
APA. Inobeyingyoxmphysicien'sinsmxctions,
I tmstym
session
in
amther
guaranteeing
participation
are
very
your

andhopewewillbeebletooonthme.

soon;

Getwellsoon!
Sincerely yams,
Fink, M.D.
Professor of Psychiatry

Max

'1‘ka

�</text>
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                    <text>October 17 , 1966
Dr. Jonathan 0. Cole

National Bank Building
6917 Arlington Road
Bethesda, Maryland

20011;

Dear Jonathan,

is a preprint of a report which hasheen
. In
acceptedbytheAmhives ofGeneralP
we
wr
editorial,
an
te
suggest
addition, the J
t
Emlosed

and

I

am

enclom a copy of ﬂat editorial.

Iamlooking forwardtoseeingyoumay.

My

best regards.

Sincerely yours ,
Fink; M.D.
Professor of Psychiatry

Max

mka

�</text>
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                    <text>October 17 , 1966
Dr. Enoch Callsway

Chief of Research

Porter Neuropsychiatric Institute
Parnassus Avenue
San Francisco, Califomia 94122

The Langley
l#01

Dear Noch,

to have missed the trip to San Francisco this
week-em. I trust the sessions of the Research Society
Sorry

‘

were as good as the program promised.

IhadbeeninvitedtoacompmyDr. freedmanandat

the last

business.

moment he

for me to
Trust

Since

I

go alone.
we can

decided not to go because of other
not a umber, it seemd J'Juppropriate

am

continue our discussions soon.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>October 1‘6, 1966
Dr. A. J. Frey
Sandoz Pharmaceuticals

Hanover,

New

Jersey

D7936

’-

DearDr. Prey:

MseofusmnIBvemtommﬂidtmingthe

pastfewyeara, feelagmatdcalofsomowathis
untimely death. On many occasions, we have discussed
I have
clinical and experjxwmzal psydnpramacology.
He
was
a
found these discussions most stinulating.
tradition.
gentleman in a very fine Enopean
My associates and I will be glad to! participate

intlneatablishnentofaednlarshipfmdinhism

,andwilldoso,ifyouwillimica’cethepmperfm.
Sincerely yours,

Pink, M.D.
Professor of Psychiatry

Max

mfkp
cc: Dr.

m1}.

�</text>
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                    <text>October 1'4, 1966
Dr. Ali Keskiner

Missouri Institute of Psychiatry
“00 Arsenal Street
St. Louis, Missouri 63139
Dear

_

Ali,
Enclosed are two capies of the fluphetuzine paper,

oneforyouandoneforﬁnanandammxoopyofyom

nanuscript.

Pleaseeditthisandpermpsyoucansemm
Wedoopybackwith'hmnwhenhegoestomhington.
My

best regards.
Sincerely yours,
Max

Fink,

M.D.

Professor- of Psychiatry

11‘ka

�</text>
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                    <text>October 11‘, 1966
Dr. E. Craig Coats, Chairman'
Coumittee on Admission
The New York Acadany of Medicine
2 East 103 Street
New York, New York

Dear mu Coats:

Iwillbepleasedtoappearbefomﬁermmittee
The New York Academy of Medicine on
Wednesday, Navanber 2, 1966 at four o'clock.

on

mission of

Sincerely yours ,
Bin Fink, M.D.

Professor of Psychiatry

..A._..

.‘F‘...—x‘.

7.-

“PM

10029

MF:kp

'

�</text>
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                    <text>v‘a

-.

,.‘_

.7

in.“

_

,w

__,_.,

a.

v...-....:....—v.wv.‘v

w,

1w«:my.-—r

., nvF'n-WJ'J“

October 12 , 1966

:E

,v~

~

Mr. Leonard I. Weinglass
#3 Bleeker Street

Newark, New

...=

.

sv—v,

‘

,,

.r

..,.&lt;,.

w...

r,

\.

1._.._.,;y.,

Jersey

Dear Mr. Weinglass:

I have just reviewed some of my files and I am writing
to inquire as to the present status of the case of Thomas
Trantino. Since discussing this with you, I have had an
opportunity to review this problem with some of my associates
and each one found the problem an important one.
Has

E

there been any progress in his review?
Sincerely yours,

E

Fink, M.D.
Professor of Psychiatry

5

Max

1.:uw

MF:kp

�</text>
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                    <text>.

wmwww

.1.va.u,7—, ,-

.7...“

_

,

_

nun-r.

~n-

w.

x

m

October 12, 1966

National Aeronautical and Space
Administration
Washington, D.C.
Gentlemen :
Would you kindly
which we may write to
1965, edited by I... D.

indicate the appropriate office to
obtain a copy of NASA Report SP-72 ,
Proctor and

R. May, which compares
man using various

EEG changes in
This study has been cited in a
methods.
quamtitative
recent review and is of specific interest to us in this

the masurement of

Departmt.

Thank you

for your cooperation.

Sirwely yours,
Fink, M.D.
Professor of Psychiatry

Max

HP:kp

'

.

Vw

ma

WWW

;v'~'!J-I""4I'I

�</text>
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                    <text>.v-v-

Ayulwmmur.

October 12 , 1966

Miss Darlene Wilson
Box 68

Crozet, Virginia
Dear Miss Wilson:
At the American EEG Society, I learned of your
interest in working in an EEG laboratory early in 1967.

are establishing a new quantitative EEG laboratory
at the New York Medical College - Metropolitan Hospital
Center. Our specific interest is in computer analyses
of EEG signals as applied to the measmement of psychotropic drug effects. If you are interested in relocating

We

to

New

York,

I

would be pleased

to hear from you.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>October 12, 1966

I».

George Webb

School of Engineering
Johns Hopkins University

Baltimore, Maryland

Dear Dr. Webb:
Mr. Richard Wexler

of

Time

-—

Data Corporation has

refmedtoyommportoftheueeofaoonto‘mognam
in glowing terms. If a reprint of the report recently
presented is available, I would be grateful for a copy.
Many

thanks.
Sincerely yours ,
Pink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>in

n.

mm? “are"! m

”M‘"

:4

MV’m-w’P-ﬁ'wt

~‘-¢‘

1-.

» “~"-'e,aa‘.'1ﬁwb-'V~’r'

v

~v'

&gt;

warm—w

-

wan-u

w...“ ~nrwgwwn mu

-

.

- .

--.._~.,.-_,..

.

tap-W“

Dr. Donald 0. Halter

Brain Research

U.C.L.A.
Lon Angelou.
Dear

Institute

California

Don .

I was quite interested in your report
to the American EEG on Saturday. as well as
the abetract of the report by Jan Berkhout.
either of these are available in preprint
If
form, I would be grateful for the opportunity
to read than.
Incidentally, it you have any other recent
reports which are now in prose. eepecially tho-e
that you are presenting in the more esoteric
computer journals. I would be grateful for the
opportunity to read there an well.
pleasure to hear your
It 1: alwnylMyabeet
regarde.
presentations.
Sincerely yours.
.

my”

,

October 12 , 1966

-

wyvmw-MV—pw-wnWr—v;mmww

.

ﬂax Fink. I‘D.

Professor of Peydhiatry

--

'u

n

..

men.

.

v-w-w -y.‘

w. egﬂz

1.:

,.,

.

7‘

�</text>
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October 12 , l966

Dr . Robert Cohn
U. 8. Naval Hospital

Bethesda, Maryland

Dear Bob,

I have been interested in
the EEG, and I am most
of
counter analysis
interested in your report in Denver. Is a
preprlnt available?
Many thanks.
As you know,

Sincerely yours.
ﬂex Pink, ILD.

Professor of Psychiatry

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Max Fink, MD.
Department of Psychiatry
Hew York Medical College
5

East 102nd Street

New York, New York 10029

Octobor 12. 1966

Dr. Barnard Saltabarg
nqpartaaat of Payohlatry
Tulano Uhtvoralty school of nadlolno
new Orleans. Louisiana
boar Barnlo.

I very anon onjoyod our diaculalona 1n
I an.grata£u1 tor your klndnoaa
in introducing an to chk'woxlor.
As you know. I on oopaclally interaatad
tho
various digital analyloa of BIG and
in
would ho loot gratuiul for an opportunity to
road tho taper: of tho Eula». studtaa to whloh
Donvar and

you alluded in our diooooalon.
Hy

boot regards.

lino-rely yours,
lax rink. 3.9.

Protaooor o: Payohlatry

llzkp
co:

Rob-rt Hoath

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                    <text>OCtObOr 12. 1966

w

,

.,.

-&lt;—.

In,»

.mfn

Dr . Joseph Wsissnbaun
Massachusetts Instituts o! Tschnoloqy
Boston. Massachustts
Dsar Dr. Waissnbaun:
In reading tbs prograsxot ths ninqhaqpton
ACE msstinq, I notsd that you ars prsssnting a
rsport on ”ms Couputsr in Psychiatry. "
I an in the procsss of comistinq a rsvisw

of this subjsct for a forthcosinq tsxtbook of
psychiatry. and I would bs gratstul for tho
opportunity to sss any publishsd ants: ial that
you say hays availabls. sspsciaily any to which
rs fsrsncs may bs ands .
Many

thanks.

aincsrsly yours.
Max

rink. NJ).

Protsuor of Psychiatry

�</text>
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                    <text>October 12 , 1966

Mr. Richard Kepensky
EEG

Laboratory
Hospital

U. S. Naval

San Diego,

California

92134

Dear Mr. Kopensky:
At the American

Society, I learned of your interest
laboratory early in 1967. We are
establishing a new quantitative EEG laboratory at the New York
Medical College - Metropolitan Hospital Center. Our specific
interest is in oonputer analyses of EEG signals as applied to
the masurmaent of psychotropic drug effects. If you are
interested in relocating to New York, I would be pleased to
Mar from you.

in working in the

EEG

EEG

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>actobur 12, 1966
Ex. Rebert C. anhleh
Medical Liaison staff

Clinical Investigation Department
Smith. Kline and Prendh Laboratory
1500 spring Garden Street

.

Philadelphia, Pennsylvania 19101
Dear Bob.

I would like to bring you up-to~dnte in our
barbiturate ~ 830 study. The data collection ended
in June and during the past few nonths, sanples at
every 12 minutes were selected in relation to the
reaction tine experience. These samples were dhsdked‘
for nrtefact end the data of‘the various subjects was
put on a disk.
_

The

,

first

analyses were to determine Whether

there were any significant differences in any of
the EEG variables in the four groups prior to drug
administration at any of the treatment periods. 'The
datn'denonstrnted that the groups were equivalent
for each of the EEG variables for eedh of the tour
drug conditions. with the exception that three of
thirty~seven indices dhowed considerable variability
during the first study in these subjects. That is.
some of the subjects ethibited lesser amounts of
alpha activity and more beta activity in their tirlt
recording than in the subsequent three recordings.
Thin observation is not unique since many
observers have reported that patients any be very
anxious during the first session and perhaps this
single record should have been thrown out. However.
since ditterent treatments were used in the first
drug period on a random basis. we do not think thet‘

will significantly bias the overall
5:1.
"hi.

dhenge

�'Kr-(‘F‘

Hr. Zudhlcn

~2-

Octdbcr 12. 1966

Tart: £6: dirtnroncun ascrthiblo to drug ottacts

ondh tint period are naw in progresl and I hnva
bacn natured by my 8:. Louis Isaociatas that tho

at

data thould h. avatlahlo within eh: next tun wicks.
as I have this I w111.cwll.you.and will
arrangc for up to go over them together.
Thank you once again for your interelt.
Sincerely yours.

As soon

Max

Pink. H.D.

Professor of Paychiatry

�</text>
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                    <text>October 12, 1966
Dr. To P. 8. watt.
Geigy Pharmaceuticals

P. O. Box 430

Yonkers.

New Ybrk 10702

Dear Paddy.

I presented the proposed study of Tegretol to
Dr. Itil when I visited St. Louis last week. The
modifications which you suggested seemed agreeable.
he hesitated undertaking a study immediately because
he had just instituted another study in the hospital,
and preferred to wait a short while to stabilise that

program first. He will be in touch with you.
With regard to my comparative study of cyclasocins
and imupramine in depressives. I an new selecting
yatients. Dr. Bird of Sterling-Winthrop indicates
that they would prefer obtaining imipranine on the
and putting
into capsules.
open market, crushing
rather than obtaining a special supply. Many thanks

it

it

for your kind offer of assistance.
My best regards.
'Sincerely yours.

anyway

Max

Fink. M.D.

Professor of Psychiatry

�</text>
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                    <text>Octdbdt 12. 1966
Dr. Enron H. Itil
Missouri Institute of Plyohintry
5400 Araanal Street
St. Lenin. Hinuouri 63139
Dear Turin.

I boiiovo it would be oppropriata for us to
the fluphenazine decanoatc material at
present
the ABM? mating
you. I will be vary glad to
If aggroublo toassuming
that Ali will present
an
write
abstract,
n

o

it; or if
will
.

he

is unavailable. that either

you or

I

Perhaps you would consider a concurront
presentation of our cyclouorino symptom provocation
have had an
studiol. for by that tins Jovan will
month
followbup.
tho
six
complete
Opportunity to
It was nice being with you in Donvor and I
look forward to seeing you in Whihington.
Best regards to the famiky.

sincoroly yours.
Pink. Min.
Protonaor o: Payohiatry

Max

erkp
P.8.

Tho

boat reservation for washinqton on Monday.

air shuttle. Ank for an
open dhuttlo ticket and u. can arrnngo to go
on the Inn. flight.

October 24. in tho

�</text>
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                    <text>October 12. 1966

Dr. Mcxncn Cattoll

Journal of
1300

thk

New

Drug:

Avenue
ﬂaw Ybrk. New York 10021

00:: Dr. Cattnllt
Hy associates &amp;t tbs His-ouri lattitnto
of Psychiatry are pleased to submit the
enclosed report “Clinical'ndboratory Tout
standards in adv Drug Trials” for your
consideration for publication in the Journal
of New Dru I. “b believe that this proEIan
of IaEErntory
.tandards 1n nuw drug avalan1:
an Laportant one in all new drug
tionn
evaluations and trust that our qpproadh may
ha of intcrcnt to your readers.
Thank you for your canstdoration.

.

sincuroly yours.
Max

Pink, H.D.

'Protcsaor at Puychlatry
Hrakp

cc:

Dr. Holden
Dr.
Dr. Simeon

Itil

�</text>
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                    <text>Octdbor 12. 1966

‘

Dr. Roland Donate

The Georg. Withington

university

Bianotric Laboratory

noon 618

-

1145 Hinetocnth

Stroot. n;w.

wadhington. D.c. 20036
Dear Ron.

I have chucked with Don Shapiro and I
think he will be available on Tuonday aﬁtcrnoon,
October 25. in Whahington. Dr. Itil will he at
the unetingn and if we can set aside a major.
portion of‘tho afternoon we dhould be able to
make the necessary decisions regarding the
high data ~ low dose Chlozpronazino - schizophrenia
study.

I look forward to toning

sessionl.

My

you at the 30030
best regards.
sincerely yours.
ﬂax Fink. M.D.

Professor of Psychiatry

ﬂrzkp

cc: Dr. Donald

M.

Shapirb

�</text>
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                    <text>October 10. 1966

‘Dr.
A

M
.

.

.._P,.,

.1“.

3.

—..~n-5w.-v~..—_

--.‘

J. 8. c. Holden

Missouri Institute a: Peychietry
5400 Arsenal street
St. Louis. Missouri 63139
Deer uike.

m.

halo-ed is e xerox of en article from
the October 3. iuue o: the J.A.H.A. which
1: directly relevant to the
me.

am):

you

for spending

no me}: time

with

sincerely yours.
Hex

Pink. $1.0.

Professor of Psychiatry

)1?ka

�</text>
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                    <text>h

,
l

.
~

October 10. 1966

Dr. Jonathan

0. Cole

National Bank Building
6917 Arlington Road
Bethesda, Maryland 20014
Dear Jonathan.

a...

..
.

VIVA.

nrnnm—uwmw-«nwvmo-my

r
w

“2—.

"I"

7???“um

Enclosed are couplets budgetary estimates
for the proposed study program “Quantitative

Studies.in Psychopharmacology“ (MH-lBBSE—Ol).
The salaries are consistent with those of
the College. as are the listed fringe benefit
components. I have estimated the first year

EEG

operation with some of the personnel beginning
at mid—year. and have added a machine operator
in the second year and an additional clerk in
the third. The program is planned so that by
the middle of the second year (1968). we will
have enough personnel to carry on a second
conputer shift, thus providing adequate facilities
for the service element of this proposal.
The program

director is identified as a

physician-neurophysiologist. The comuter
director will hopefully be someone with the
qualifications of Dr. Donald Shapiro.
Thank you for your consideration.
‘sincerely yours.

Fwy-1"

nm«rm.wg-ymw

:1m'—‘¥

was-w»

vmwr

.-

Max

Pink, M.D.

Professor of Psychiatry

Mskp

�</text>
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                    <text>October 10. 1966

To whom

it

may

concern:

Mrs. Jennie Helms was appointed

to the Depart—
of Psychiatry. Missouri Institute of Psychiatry.
university of Missouri School of Medicine. from

ment

January 1965 to June 1966.

it

She left the Department soon after
was
announced that I was leaving St. Louis to accept
became obvious
a position in New York. when
that some of the research programs in which she
was participating would be curtailed.

it

In her position. she assured

some

secretarial

and typing duties. assisting my secretary whenever
necessary. Her principal work was in the handling
of data from various studies. She maintained records.
drew graphs. carried out statistical procedures and
was most useful.
Her

disposition is pleasant and she is always

neat and well dressed. Her attendance record was

good and she was prompt.

I an pleased to recommend her as a technical
assistant or secretary in any program which she
feels cppable of undertaking.
Sincerely yours.
ﬂax Pink. M.D.

Professor of Psychiatry

�</text>
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                    <text>October 4. 1966

Dr .
Thu

Eli.

Ivan

r.

Bennett

Lilly Rescue): Laboratories
Lilly and Company

Indianapolis . Indiana

D.” IV“

m‘ﬁ'ﬂ’u-

«v

——

7w"

Wrzm—m.

M14”

cyclonortno data was owned on 5/18/66.
boon:- uprouod with tho
viewing the data as symptom
possibility
provocation. and hold up the report until 6 months
follow-up. This will ho «20:910th in Hovubor and
tho rcport should follow noon.
Hy

Tho

nuoohtuofand I
“ﬂunk you

w-

w

rink. NJ).
Professor of Psychiatry

ﬂax

4.

Ivy-gar”

,

unvwm—W

tor your mutant .
smcoroly your: .

W”.

‘g'v,

I

”ﬂap

�</text>
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                    <text>‘p‘i’nhV

-m-m

-:

wm’r—

:
m.

'zv—In

"‘s—rwz-z-

r

octobsr 4,

1966‘

6. Bird

Dr. Jossph

Director. Division of Clinical Rssssrdh
sterling-Winthrop Rosoarch Instituts

nonssslssr.
Dos: 3b..

Row York

Enclossd is a propossd protocol for tho
study of cyclazocino in depressive disordsrs.
I would be grateful for your connsnts haters
tho proposal is otticislly submittsd and
approvsd.

srs beginning a now rotation
opportuns tins to initiats this

As ws

of rssidsnts in tho usntsl Hygions Clinic.

this is

an

prOposal.

I will hs away until
you early nsxt weak.
Many

Monday.

so will

csll

thanks.

sinosrsly yours.

as:
rink ‘H.D.
o: Psydhistry
Protsssor
l33kp

.é‘.

�</text>
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                    <text>"'\\

Octdbdr 4. 1966
Mr. Thomas Buckley
new York rises
229 West 43rd Street
New Yerk. new York

Dear Mr. Buckley:

favorable presentation of Dr. Leary's
the New York Times of October 2.1966.
in
program
does a major disservice to the community. LSD
has been a research instrument for nany years.
and even when offered to volunteers (before l962~3)
was generally not accepted for a second session.
Since Dre. Leary and Huxley painted the LSD
experience in a most enthusiastic light. and since
the press (including the New Ycrk Times) has
reported these illuconceived pronouncements most
favorably. the abuse of L8D has become extensive.
-.Thue. your favorable advertisement will enhance
the movement. despite the smell suggestion of
The

-

danger which you have hidden in parentheses in
the 6th paragraph of the essay.
The statement "(LSD has in some cases triggered
longv-te’rm psychotic reactions among borderline schizophrenics. and the possibility of permanent mental
derangement and depreeeion among ostensibly normal
users remains a major concern)” is too weak a state»
ment and is incomplete. The "triggering“ of psychosis

in borderline schizophrenics is probably, but recent
reports suggest that the schizophrenic is not the
most vulnerable. Indeed. schizOphrenics are often
tolerant of large doses of the drug. The most
susceptible subjects may be those with cyclothymic
tendencies

—

i.e..

highly emotional. vacillating

“of

between extremes
elttion and depression. Prolonged
LSD reactions have been observed in precisely such

individuals.

'

�unfortunately. in man's psychosocial development.
is the stage of development when emotional

adolescence

outbursts
controls are under-developed and emotional
common. It is precisely at such a time when it is most
difficult to control the response to exogenous toxins
(.ege:

LSD’

e

Continued favorable reporting of LSD abuse by
the press does the nation a disservice. Such advertising.
&gt;conbined by mild admonitions, can lead to abuse of LSD
and increasing tragedies. One would hope that Dr. Leary's

less fully and a more direct
exploits would be reportedwould
be included, and not
the
of
dangers
statement

within parentheses.

for a scientist
Incidentally. it is difficult
he
trained to
since
is
to express his anxieties.
within
journals
scientific
in
conclusions
state his
soothsayers.
observations.
Prephets,
the
the limits of
and Charlatans have no such limitations. and may asks
more lurid copy. Enclosed is a copy of a report from
my laboratory Which will appear in a forthcoming issue

of the Archives of General Psychiatry. The conclusions
are htatedfhesitantly. But, our impressions are that
LSD in adolescence is a dangerous drug and its dangers
should be as definitely stated in the lay press as the
spiritual benefits are described.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

�</text>
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                    <text>Sﬂptldbﬁr 29. 1966

Dr. Paul

anotte

Juliette.

Quebec

Hapital Saint Charles
Canada

Dear Paul.

enjoyed talking to you in
returning to New York have
been able to review the opportunities and the

I very

mudh

Madrid. and since

study programs at this College.

I would, indeed, be interested in reviewing
your curriculum vitae and in arranging for you
to visit New York at your earliest convenience.
My

best regards.
Sincerely yours.

‘.

.,,r,

,
u.”

Max

a

Avg—“-

73;.“r-"x-“uv

‘*"&gt;¢;

ﬂww—m—Vr—g-zum-

,

Pink. 3.0.

Professor of Psychiatry

�</text>
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                    <text>Septeube: 29. 1966

Dr.

J.

M.

c.

Holden

Mieeouri Institute of Plychiatry
5400 Arsenal Street
St. Louis. Micsouri 63139
Dear Niko.
Turan was here. HI spoke about the sun's
length. Last night I was reading some
notes from the ECDEU Program and the attached was
included. which I an eanding you for your interest.
I plan to be at HIP next Rodneeday. and I
would be plea-ed if you could work out eon.
tine with Turan for no to go over some of your
studies.
My beet reqardl.

at

When

eomo

Sincerely yours,
ﬂax max,

11.1).

Professor of Psychiatry

81"ka

�</text>
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