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                    <text>_

movember 14, 1967

.o\‘—-—w.-.~1_.~..v..-.4,

‘

".

”

;,X Dr. Joseph 6. Bird.

-Director of £xperimﬂntal Medicine
Sterling«w1nthrap Research Institute
RensseIaer, New York 12144

‘

r~muw_yrw-¢-I&lt;-v~v&lt;ﬂ-

'

‘

Ifﬂear Joe,ﬁ

m.

'

Thank you very much-for

A

open study of

cyclazctine as

the grant~in~aid in'sunport of the
antidepressant. We are,~indeed

an

”grateful for your-continued support.of this study program.

just compTeted an additional raport concerning the
background for the recommanéation of cyciazocine as an
antidepressant. This report #111 be presented at the forth«
coming meeting of the ACRP in Puerto Rico. éEncIosed is a copy
I have

EEG

for your informatian.l

'

‘

‘

3

,

It was a great pleasure to have Drs. Rosenberg and warsha11
visit with us on Friday“ I trust that they will share with yea
.

some of our

recent experiences with naioknne. Dr. ﬁarshaI]
indicated that he wou1d like to.discuss a study.of oxypertine,
and I look forward.to meeting with him next Monday.
»

Again, our thanks.
SiﬁCerely yours,
Max

Fink,

M,D.

Professer of Psychiatry

'

MF:kp

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                    <text>November

'

Dr.

J.

M.

1!,

1967

C. Holden

Missouri Inst1tute of Psychiatry
5400 Arsenai Street
St. Louis, Missouri 53139
Dear Mike.
I

regret to

Say

that the

first report

of the

CﬂT

study

has not been accepted by the Aachéveé 05 Genekat Psychiaxng.
Perhaps you wou1d discuss with Turan and AIﬁ the aiternatives.
Surely. Campnahenbiva-Raychiatny or Psychophammacoﬁogia are

exceient Journals which may consider this report favorany.
For e1ther one, the references may have to be retyped.

If

I can be

of any help, piease call on

me.

Sincerely yours.
Fink, M.D.
Professcr of Psychiatry

Max
*

Mszp

a
A

”WJ’W‘KWVW

�</text>
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                    <text>I

{W

.

,u—u

,

-w

Wur-w-rwn-x. ”at ..w
,

-.».m—-p.v. .‘ mm»,

was‘ «(w—www.mw—m‘W—"mvam—

I

E

ﬁovember 20, l967

Sr. ﬁilliam R. Tabor
ﬁ. ﬂ. Robins Company
l407 Cwouings.9rive
Richmond. Virginia 23220
ﬂoor

Eill,

Enclosed is an outline of an experiment to be undertaken
with‘the medical students at the How York medical College. As
part of the class demonstration series in pharmacology. this
demonstration is scheduled for January 9.

I would appreciate your cooperation in making available to
Supplies of fonfluramine and concurrent samples of amobarbital,
dextroamohetamine and placebo as outlined in the attached protocol.

we

'

If this is possible, the oxperiment will provide us with
additional information concerning the sedative or stimulating
Qualities of fenfluramine. I will complete the forms necessary
to consioor this research study. Many thanks.
Sincerely yours,
Max

Fink, $.9.

Professor of Psychiatry

ﬁszp

�</text>
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                    <text>November 20. l967

Dr. Donald F. Klein

Director of Research
Hillside Hospital

Glen Oaks, ﬂew York
Dear Sun,

In response to your request. enclosed is a list of my
puhlications. All the publications between l955 and 1963
resulted from work at Hillside Hospital. In addition there
are citations in l953, l964, l965 and l966 which are marked
in the list, which are predominantly the result of work done

at Hillsida Hospital.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                  <elementText elementTextId="102354">
                    <text>November 20, 1967

William Martin
NIMh Narcctics Research

Lexington Kentucky
'

'

Facility

Dear Si11,
ﬁe would

like to undertake some studies with tetrahydro»

have been toId that we wii] have to file our
At 9?. Levine’s suggestion. I am writing to request
your permission to refer to the pharmacaIQQic data in'your
1&amp;3 when we file our own.r May we do so?

cannabinol.

own

Ifkﬁ

we

.

Taank you

for yaur ccaperatian.
Sincerely yours,
Fink, M.0.
Professor of Psychiatry

Max
HF : kt:

�</text>
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                  <elementText elementTextId="102353">
                    <text>t

November 20, 1967

Dr. Harris

University of Kentucky
Lexington, Kentucky

Dear Dr.
We

g

E‘

i

i

Isbeii

Department of Psychiatry

Isbeii:
are interested in undertaking studies of tetrahydro»

cannabinoi and have been told by

own IND.

At

their suggestion,

NIMH

that

we

must

file

our

writing to ask your
permission to refer to the ﬁharmacoiogic data in your IND

when we

file

our own.

Thank you

May I

I am

have your permission?

for your cooperation.
Sincereiy yours,
Max

Fink,

M.D.

Professor of Psycniatry

Hszp

�</text>
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              <elementText elementTextId="30816">
                <text>mfp-05-00-021-8-495</text>
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                <text>1967 </text>
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              <elementText elementTextId="30818">
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              <elementText elementTextId="30820">
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            <elementTextContainer>
              <elementText elementTextId="30821">
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          </element>
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            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30822">
                <text>&lt;a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank"&gt;IN COPYRIGHT - EDUCATIONAL USE PERMITTED&lt;/a&gt;</text>
              </elementText>
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          </element>
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              <elementText elementTextId="30823">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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          </element>
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  </item>
  <item itemId="3081" public="1" featured="0">
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      <file fileId="1726">
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                  <elementText elementTextId="102352">
                    <text>ﬁovember 20, 1967

3r. Jernme Lev1ne

Psychopharmacology Research Branch
3133

Sethesda, 3ary1and

Sear

Jerry,

Dr. Freedman has suggested that we look at tetrahydro»
cannab1n01 with our EEG programs. As I indicated ear11er this
year, we wou1d be pIeased to do so when supplies are availabTe.
,

I have aIready f11ed an application witx Mr. G1ardono for
narcatic stamp 31th special permiss1on for mar1juana, and am
writing to ﬁrs. 3art1n and 133911 for permission to use the1r
pharmac01ag1c éata.
a

'

;

1

be

I am

f1led.

requast the necessary I33 forms
obtain these frcm your cff1ce?

wr1t1ng to
Can I

wh1ch must

take th1s apportun1ty to congratuIate ycu on your
For those of us 1nterested in the b1c1og1ca1 aspects
of psych1atry, the programs of the Psychopharmacology Research
3ragc? have prov1ded much of the leadership of the past decade.
Hay I

appointment.

Goo

uck!

Sincerely yours,'
33x Fink,

3.0.

Professor cf Psychiatry

3szp

�</text>
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                    <text>I-w

w.wumw~nmm~.;~m=wav-wr

.

November 21, 1967
Mr. Robert Shearman
13M

Corporation

411 Montague

Brookiyn,

New York

Bear Mr. Sheanaan:

Pieased be advised via this communication that the New York
Medica1 Coiiege Division of Biomedicai Information Processing
requests that the fo1iowing equipment be de1ivered to be attached
to the 2701 Communications Adapter.
7698 Synchronous Data Adapter
3855 Expansion Feature
3815 Extended Capabi1ity

of

As

you we11 know,

this equipment is being ordered in 1ieu

inabiiity to de1iver an adapter for the 1800. A January
1968 deiivery is imperative because of the deiivery of the front
end oquipment at that time and because of an already shattered
IBM's

time schedu1e.

This equipment is to bo bi11ed as part of the
Max Fink.

separate bi11ing statement to Dr.

Sinhere1y yours.
D. M.

Max

kp

Shapiro; 0.362 and

Fink,

M.D.

�</text>
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                    <text>vaember 21,

1967

Dr; Party Biack
Jehns Hopkins Hospitai
'

601 North.8roadway

Baltimore 5, Maryland

Dear

0r. Black:

writing with regard t0 the symposium "Drugs and the
Brain.“ You were kind enough to invite-me.to submit a manuscript
and I suddenly realized that the date for submission has passed.
I am

At the request cf the ACNP, I'am in the midst of an extensive
review of Iiterahure and wiii be pleased to make the kind of
presentatien which you requested, provided that the deadline

can be moved up to mid—Becamber. I shal1 try to have an'appropriate
manuscript avaiiabia for you by that time.
'

-

Sincereiy'yaursg.
'Max Fink, M.ﬁ.

Professor of Psychiatry

Mszp

�</text>
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                    <text>(ﬂ-Kn,I“V-v¢.

‘Ygrﬁ‘u‘

r

qumwr’r’v—m'm‘a

“w‘sv

-.-.

avwnv

I!

w.

mmo-w-

a-w

”xv—Inaa

.mm

l

“7

7.
.

g.
“‘7'"

.
i
uVFW-win"...
,

,

;

Dr. Werner P;

x

.r,»

x-nyn

r“ __“.mmvnw

yr ---- in, Maw-nur- - nu.
,

smasher 21,

' '»')vv' Wm.“

~-

-

.

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um...»A

.n -v

,
.- n w'

w \" -

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.w~

- vvv:

.,,,,nun-nu

.v 310/ ,‘.V”t

1%?

Koalla'

Senior Scientist

‘

.

.

Worcester Foundation ib'r Experimental Eiralogy
Shrawsbury, Massathusetss-Ul546
Dear Warner,[

set your heart on accomplishing
the established mission of having all the ACNP manuscripts available
long before the meeting. I ragret that this will net be possible.
The original review of the literatura is on my desk, but this is
not a satisfactory presentation. in my discussions with Dr. Itil
hammered out a much
While I knew haw much you have

during the past few months, we have, I believe,
significant VlﬁW:0f the ralation of 5E5 changes with psychc~
tropic drugs to behavior., I would like to present a critical re»
View of our experiences and those of many other observers describing
the interaction of drugs, EEG and behavior in man. ‘This will he
available at the time of the meeting.

mare

the principal discussant of this summary. He
is intimately acquainted with my wcrk and with the total world
experience. ‘I have cansulted him and his discussion will comple«
meat the material which I am reviewing..
Dr.

Itil is

while I know this is less than satisfactory,.1 hope that you
will understand my reluctance to send you an unsatisfactory
manuscript; even far yaur ayes only, and hope that the delay will
be

justified
As

by the

results.

soon aS‘I have a

you ans‘arrange

ta

:

satisfactory document-I will send
conias as ynu request.

make as many

Thank yau for-yaurrinéulganca.

SinCeraly‘yours,
Fink, M.B.’
Professor cf Psychiatry

Max

HF:kp

it

ta

‘

.,

“rs—“T...

.,

...‘

.

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w"—

�</text>
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»

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-

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2l, l967

Dr. Daniel Silverman
269 South l9th Street

Philadelphia 3, Pennsylvania
Dear Dan,
I

have not forgotten the paper

for the

monograph of

EEG

to

effects. In response to a request by the
review the literature regarding EEG and drug effect for a
forthcoming symposium in Puerto Rico, I have devoted much
time to a detailed review of the extensive experiences in

and drug

AChP

the literature. The draft of the material presented at thew
EEG Society is unsatisfactory and I have delayeo sending it
to you pending some critique and review by my associates.
This has. and will delay my manuscript for a few more weeks.

._.

«._.1....,.¢,..I_.,_.,;,[

m'.‘h.(

v.7,

have read the minutes of the meeting and have made my
notes. From your letter. I assume weeare not bound by the
exact responses made at the meeting and I am taking the
I

liberty of responding to the questions to the best of
present ability.
I know how

only hope that

will write to

a delay means, but I can
be justified by a better product. I

exasperating such

it will

you

shortly.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

‘Max

MF:kp

my

7,.

mums-q].

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�</text>
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.74

new”,may,” Am-

-

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h

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November

3-, p—va' . ,v......_--..,-.¢-.-w:»‘Vm'm::r-.x|ry&lt;‘-W~NWVKav,'Vrmi.VmW,rv:u-,x
y"

WWI—(W:~.-;mqyuwmz

21, l967

Dr. Harvey Minchew
Bureau of Medicine
Deputy Director
Food and Drug Administration

Crystal Plaza

5

Zle Jefferson

Davis Highway
Arlington, Virginia 22202
Dear Dr. Minchew:

writing to request a copy of the selected bibliography
of marihuana. covering 1950 through l967, which has been prepared
by the FDA Medical Literature Branch.
I am

A

stamped, self~addressed envelope is enclosed for your use.

Thank you

for your cooperation.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MFtkp

'6

mm.

"-K\-‘(11I"F'

arm-m,“ rl'v.r"~ umv

�</text>
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-

M'r'v- or .qu-wz-"Arw-w:
n—va

w- \z-um-V-srﬂ-I‘ﬁv, mun,

v,»

:: rip—w?- \wm

W'r31.1."? a

--

”Lyn-VMR‘YIEWW LY-new‘I—‘W'

I'Wl'nrA—J‘yx—

w

7.,”

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‘

r, .I... .w

&lt;

mum..-

.,

my.- .

“wax.” “\“p--‘y‘y_:5v“' . 1..."...

ﬁovember 21, 1967

world Health Organization
UN Headquarters

First

ﬂew

Avenue and 42nd
York, ﬂew York

Gentlemen:

'

Street
‘

’

I havé just read of a new‘y'hub11shed repart by the
World ﬁealth Organization’s group on research in psycho«
pharmacology entitied‘“ﬁesear¢h 1n Psychopharmac0109y.“
Would you kindly indicate the ava113bi1ity and source
of this document and its cost?,
:

Thank you

for your coopération.

Sincérer yours,
Fink, M.D.
Professor of Psychiatry

'Hax
MF:kp

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                    <text>i i!
’1

-2x

,

«rm—'11

lK-O‘WV'.

a
i

Rovember 22, 1967

Dr. Gerald Klerman
Connecticut Mental Health Center
34 Park

New

Street

Haven. Connecticut

Dear Gerry,

This is to confirm the change in the date of your
presentation to the Nassau~NP Society from February 20
to March l9. I will be in touch with you before that

date and
My

we can

discuss the details of your

best regards

and

my

visit.

thanks for your cooperation.

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

.Mszp
cc: Er.

Kay

�</text>
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                    <text>w—

w». ,va—u—ur-w-mn-ww-ur

'D«W.ﬁw up WM'rr-nawc-v

”:m'vkuMann

,

'mﬂv—umw-QW'"M'quvm-aumwnuuv\‘yvennvw'Wn-‘"

navember 22, 1967
"WV‘"-"'""','1"'

7w

?-

w“

Br. Pau1 Kay
15 Canterbury Road

Great Heck.

New York

-1

\r.“

..,

”yum—,(vr

Bear Pau1.
I have been ab1e

.,-

mw.

.—

,"y-v—w-e

presentation to the

to change the date for the

K1erman

Nassau MP Society to ﬁarch 19. Abe
Lenzner w111 prepare the program for April 16 and J. Stanton
can accept for February 20.

"a

"I

"a

‘4

v.“

~

I have ca11ed Br. Klerman and he is ab1e to come on
March 19. I am writing to him t0 confirm this change.

m

Sincere1y yours,

rowan-nun

".Hm-V‘

Fink, M.D.
Professor of Psychiatry

Max

HFtkp

.-r~ www- 'v'nvn.vw'rm-’w—-&lt;1'J

�</text>
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                    <text>n
A»,

.«&lt;

«r

wrn—vm-mvwmmrm

v,

~11”

3.5."

my...

4—...wr.“... n,
q

"1~

v.

;nv—v-y'ﬂi"‘I'W‘W'J-MW*SWWWW'EtrLJv-,mp-Jrvgx v

InwptiT-s

Frv.‘ ..m.¢.mn—~~.¢w-m-

,an

,~rv.~wﬂwm&lt;wymwnm Y‘lan’vn‘JMHP‘r-umw»

J...” "my...

November 22, 1957

Dr. Alain Sanseigne
Squibb International
460 Park Avenue
New

York, New York

near Alain,
Dr. Denham

enjoyed the

visited with

visit

practitioner.

He

us

this

morning and I hope he

as much as I did. He is a charming experimental
sat in on a meeting with the patients and

their questions in a witty and enthusiastic
ﬁrs. Eucci ané Simeon joined me to discuss his
experiences with fiuphenazine and we found his reports interesting

answered some of

manner.
and

heipfui.

Thank you

regards.

for suggesting that

he

visit

with us.
r

Sincereiy yours,
Fink, %.9.
Professor of Psychiatry.

Max

MFtkp

My

best

Vina-"ulna suym- .j‘v‘g "mum

�</text>
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                    <text>“mm...“k.“&gt;mtmum‘gnm(~.,a~«row-3»
"tum“:mewt'nwuyw'apwhyr'17,..vn; _.

.... \w

,-

my”.

.,-.,.»~xo-m—m-n-w,.vmr

WHWW'WJWWW

-

\nw‘ .4“. av-m.:~vw-w—x~-m-v—rwun-mnfw

November 22, 1967
Mr. Robert Shearman
IBM

Corporation

411 Montague

Brookiyn.

New

York

Dear Bob.

just received and read the 18H Computing Report
for the Scientist and Engineer, Vclume 3, Number 6. This was
I have

very interesting and I note that aariier issues are availabie
through your office. 15 it possible to receive copies of
Volume 3, Nos. 1, 3 and 5?
Nany

thanks!
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

kn

.

-

,

�</text>
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                    <text>November 27, l967

Dr. Robert L. Kahn

Associate Professor
Department of Psychiatry
University of Chicago Hospitals and Clinics
950 East 59th Street
Chicago.

Dear Bob,

Illinois

60637

'

Perhaps the best way to describe the project at Gracie
Square Hospital is to review the enclosed application to eIHH
for support. I have always regreted that we did not complete
the study programs at the time that we were intimately involved.
In the ensuing decade. little additional information has been
published and I think that what we knew then is still much of
the information available today.
The

ECT

.

interest in multiple monitored

ECT and in unilateral
reevaluation
the
a
of
justifies
process. By utilizing the
I
me
available
to repeat and verify
hope
to
resources
today,
the observations we made then and add to them the rigor of more
should then
systematic collections. If the program succeeds,
be possible to write an important chapter in the history of
'

it

this treatment method.

I should like to be able to call on your experience since
think you can provide a critical judgment of the social and
—psychological aspects of these studies.

I

My

best regards.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:hp

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                    <text>November 27, l967

Dr. Merle Gibson

_

Division Neuropharmacological Drugs
Bureau of Medicine - FDA
Crystal Plaza
Arlington, Virginia_
Dear Dr. Gibson:
I am

writing at the suggestion of

the Psychopharmacology Research Branch,

instructions for filing

permit this

extracts.

Dr. Jerome Levine of

NIMH

the appropriate forms

to request

that

would

laboratory to undertake studies of marijuana
-

are interested in determing the clinical and EEG
effects of.these substances in volunteer subjects at the
New York Medical College. The focus of the study is to
determine the EEG profile and the concurrent behavioral
effect of parenteral administrations.
We

Dr. Levine has indicated that supplies will be available
from his office, as soon as we have complied with the FDA
regulations. Would you be so kind as to send me such information
as I may need to comply with the regulations?
Thank you.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>.4.»gk;"~'l7

Inv»

aw

av.“-

Law

—-.~y&lt;«

November 27, 1967

Dr. william Triebel

Gracie Square Hospital
420 East 76th Street
New

York. new York

Dear

Bill,
Thank you very much

study program.

staff

on December 6.

us get started in our
to attend the meeting of the

for helping

I am planning

.

Enclosed is a draft copy of a memorandum to be distributed
at that meeting. Would you please review this and if it meets
with your approval, return it with an indication as to the number
of cepies that should be made available.
Do

staff?

it best to distribute these at the meeting
general mailing to the attendings of the hospital

you think

or to have

a

_

Sincerely yours.
IMax

Fink, H.D.
Professor of Psychiatry

MF:kp

�</text>
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                    <text>nv....«.-

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”wry“

.

November 30, 1967
C. B. Mosby Company

3207 Washington

St. Louis, Missouri 63103
Gent1emen:

Piease enter

subscription for the journa1, Cttnicat

my

P1ease address copies to:

Phanmacoﬂogq and Thenapeutica.
Max

Fink,

M.D.

39 Ar1eigh Road

Great Neck,
Piease bi11

me

New

York 11021

at:
Max

Fink,

New

York Medica1 Co11ege

M.D.

Department of Psychiatry
5

East 102nd Street

New

York,

New

York 10029

Thank you.

Sincere1y yours,

Fink, M.D.
Professor of Psychiatry

Max

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8aar Taran,
seconﬁ varsicn 0f the EEG~antiaﬁyrassaﬁi
ta thank yam {ﬁr
is much bgtter and i want
paper. I think
1ecat1ea of figurag»
your comments. Pieasa mate the saggestgé
fruﬁ
year collectiuﬁ
and if pessible, wauEd you saiect fiﬁures
Gags thai
ma.abeut’the
Cal}
at these piacas.,
ﬁhat might
them in;
yaw den‘t have and I wiil fill

Enclosed

is the

it

fit

abarmacwlegy
SecaﬁQIy, thera is a draft of-tha c11wica1
stil? in”
is
table w1th all the.citat$an$ aﬁﬁ
payar. Tae majar
1w: ma
this
tc.se&amp;
like
campieie, but I trast you mightI‘am
revise
tn
it,
going
know what your cammants are.
I

aapar

have

3&amp;6

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written

a greTiminary

tais shﬁuid

§est

be

tysed

draft of the haﬁlucinegen

by Kathy an ﬁcnﬁay.

‘

_

ragarﬁﬁv

Sincereiy yours»
Fink, M.m.
Professor 9 Fsycii&amp;try

Max

ﬁszg
enc .

'

_

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                    <text>September

l,

l967

Dr. Joseph 6. Bird

Director, Division of Clinical Research
Sterling~winthrop Research Institute
Rensselaer. New York l2144
Dear Joe,

of the investigators you might consider
for the callaborative cyclazocine study. Dr. Allen Raskin can
be reached at (30l) 495¢l393. Dr. Itil can be reached at (314)
Enclosed

M1

5—6230

is

a copy

Ext. 618.

I would

like thlt

Dr. Jovan Simeon and Arthur Zaks from

this department also be invited to the meeting, since they
have been active in the cyclazocine study. While both are
away. I will speak for them and believe that they will be
available at any time after Septemher 22.
Sincerely yours,

Fihk, M.B.
Professor of Psychiatry

Max

MF:kp

enc.
3::
my

¢'

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34;?er

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my.

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,

�</text>
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                    <text>4mwu....~w-_‘.vwaw”, ., «ya-MW} 7w:
.

Ixszwr'u —..——

"Jr!"—

September 5, 1967

Br R1chard P. Mh1te

Associata Professor of Fharmaca1ogy
Department of PharmacoTagy
The Un1vers1ty of Tennessea
’

1

‘

Memphis; Tennﬂlﬁge
Dear D1ck

to comp1ete ynur app11cation to the ﬁat1ona1
Science Foundat1on. I hape that th1s w111 go through.
I was 91eased

Enc1osed 15 a suppiy

stué1es.

During the

past

narcotic potency of

of 50 mgof

d1acety1morph1ne For your

few weeks, we have been assay1ng

Haloxene and

find that this

15

the anti—-

immediately

,

1,.

effect1ve 1n bTOCking the cantra! and behavioral effects of
hero1n In our subjécts, 2 mg ef NaToxona effect1ve1y antagonizes
20 mg of d1acety1morph1ne and does so when g1ven twenty m1nutes
before or twenty m1nutes after the hero1n. Perhaps after you
have had some exper1enca with cyclazocine, you shoqu plan to
luck
‘

at this

compound as we11.

Good luck!
,

.

$1ncéreiy yours,
Hax F1nk

Prafessor efDFsych1atry
Mszp

.1

.-&gt;4.3ivaa_;.i,:g.A

�</text>
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                    <text>September 5, l967

Editor
Psychiatric Progress

Mr. Harold Mehling,
3 West 57th Streeti
New York, New York

rt

l0019

~—.‘

v

Dear Mr. Mehling:

-"«'

4”

w;.—

—

'1)in

:‘HNVPv'a-r

avg—39‘:

vwz,

“”""-mlvv'.__

'v

that

Thank you for your letter of August 29. The presentation
I will be making at Hillside on “Computers and Psychiatry”

of the report published in the recent textbook of
psychiatry pubaished Iy Freedman and Kaplan, Milliams and Wilkins.

is

a summary

Additional information is being published in a volume
A copy of this article is enclosed.

Kline and Laska.

Sincerely yours,
Max

-.n-._—.y

.51“-

Hszp

7

’21:.me

Lm-r

WI"

:‘DETTVE‘W:

wwmrm

.qar:

”wage-A

N‘y

”7.5;‘7i1'ﬁpvh

‘5'.
Km"

A
can

ZW'VEL‘YE‘I":

z
expiry-H"

‘

_

h

Fink,

M.D.

Professor of Psychiatry

r

by

�</text>
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                    <text>aw-.w, WWW," .-. ___,,_,

r.

NF

...

.v

., .,. ‘-kmnwrrwvw'.rvw‘_WWW-N'

.

'mmm

Sebtembék 5, 1§67

‘

Dr. deﬁes H;

Satterfieid

:theways Hespitai

7
1891 Effie Street
Los Angeies; California 90026
’

h

.

Dear Jim,~

I was pleased t9 receive your letter far I have knewn ef‘
Gateways HQSpita1_for some years and'am daiighteé that this
fine institutien wiii have your suppart.r Knowing of its

‘

-"

similarity_tQIHi}iside Hospita}, I-was pieased to discuss the
deveiopment of research programs with the Ziskinds on many
occasiQns during the past fﬁw years and was mast enccuraged
by their forward iocking point 9f View; 509$ luck!
I am pleased t6 ehcibse a few of the availabie preprints
of studies recently compietad. This work was done at the
Missouri Institute of Psychiatry using the 18% 1710'~ 1620.
-

&lt;

system which I estabiished

there...

I do nct know of
.
anyene usiﬁg t iink computer succeésfuiiy
in the anaiysis of EEG signals except itS'RideSstad use for

averaging evoked vetentiaIS;

,

"

'

Please give my persenal'regards to Seth ihe Ziskinds
next you see them;

when

.Sinéereiy yearsg.
.%ax¢Fink,*%.2§.

Professor cf Psychiatry‘

:Mﬁfkp

�</text>
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                    <text>‘—

”-"erwyw

September 5, 1967
m-w...'..,_‘...,...

ywn—

,,._,,,_,,.N

Spero~whitelaw 50., Inc.
385 Park Avenue South
‘

ﬂew

York,

Haw

York 10016

n.

'r
.u
ac.-

GentIQmen:

—...,

”av—am...“

—

I should like to discontinue the malpfactice insurance
described in the attached certificate.

-w'~Yl‘-4vr"vvv

Thank you

.wm.

for your cobperation.
Sincerely yours,

.v‘mcuuw,

...

"n~v‘

w'rr

w.»-

r

ﬂax Fink. M.ﬂ.

mar-1

Professor'of Psychiatry

~

1&amp;4mmrw‘w

MW».

NF:kp

�</text>
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                    <text>Soptomber 5, 1967
Dr. Ralph Jacobson,

Associate Medical Director
Endo Laboratories. Inc.l
'.l000 Stewart Avenue
Garden City, New York_ll§33 [
.

Dear Dr. Jacobsenzv

'

Thank you very much for the initial supply of naloxone
20 mg tablets. Qur
two patients are now.taking 100 mg
a day and the second group of'threo patients will start on
Monday. If all goes well, we.will neeo an additional supply
by the lst.of October.

first

‘

.

Concurrently we have carried out our acute naloxono
experiments_using the_0.4 mg per cc Concentration. Haloxone2 mg offeCtivoly blocks_20 mg of heroin.
I an anxious to
continue this work and will soon need an additional supply
of injectable naloxone. hopefully at.a higher concentration.
I would bo-grateful if an additional supply could be made
*available. Please call me when you have some information.
_

Sincerely yours,
“1-

#rofessor of ﬁsychiatry

,1"

Iu-‘I‘vr‘rf'

I

.,,,mv,.-,w~v-u,y~,.

..
y

.

MF:kp

.

�</text>
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                    <text>~‘vv‘uﬁ an):

Wﬂr'v‘r‘mW-leﬁ

,

»

A

. “vat—W
F

«w ‘"man-ra—vm—r.

r_. n

v

.

.

u.

~‘~L,ern~

J-wwwww'wrw'mma‘wnu”II-FWAMF'I'MW‘WVQ

:

,'(1'"'V‘Iu‘:=an‘ﬁm-mut1ﬂiw~rv-vr‘m,’

September 5. 1967
Dr. John Kramer

.
A.

_.H_

..

Chief of Research
Department of Corrections

Caiifornia Rehabiiitation Center
P. 0. Box 841

._..

W

“I“?

m

Corona, California

_
..

wary,“

Dear John,
be giad to have you visit on September 19. As you
can tell, the Brotman proposal is a straight socioiogicai program
quite distinct from the medical ~ pharmacological approach that

wiii

He

'rm'mamwg-WW;.

we

use

at Metropoiitan.

If

you

get to Great

(516)‘466-3158.

room and I can
My

If

ﬂock on Sunday. give

you wish to stay over

take you in

on Monday.

we

me

a

ring at

have plenty of

best regards.
Sincerely yours.
Fink, Moﬂ.
Professor of Psychiatry

Max
.1”;

Mszp

,

,

o,

g
{w’vp

wrnw1.v—.».

.‘,":"lu&gt;,

«w

U-rj-

New

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2mm:

awar-

HWFNW

m:

4

«

:Jsﬂchﬁiﬁug

w
w,
_

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                    <text>..

v-mw-

.v-n

.1..-

Wuwnr'J—vvr

September 7, 1967

~

Dr. Alain Sanseigne

Associate Clinical Research Director
E. R. Squibb and Sons
Georges Road
New

Brunswick,

New

Jersey 08903

Dear Alain,

Enclosed is the revised fluphenazine decanoate/enanthate
Thank you for your help.

project.

'

In our discussions I believe we indicated that we could
after
start a few patients on oral fluphenazine immediately
the placebo period as a priming treatment. Or. Bucci seems
to recall this and was asking me for some fluphenazine. If
this isﬁagreeable, I will modify the project so that in
selected cases he will be allowed to use a priming dose.

tablets) of Prolixin
hydrochloride in the largest available amount (5 mg)? Thank
Would you send me a supply (lOOO

you very much.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Hszp

�</text>
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                    <text>L.

i
i
5

i

i

”AN“, w”L,l_,,_,,,,,,£m‘.,m.,n_,....w».

i»

,

_..

,w.:v..pr-

n.f,_..rv..r.~p»...,

MA

..&lt;\r*- au-

u. n apt
,
v. 4».‘.M~n
..
.

v

i

.

»

.

,..,, 4

v

,-

w”

n

.

.r'm"

1

A

4-

-.;v

mm.

.

&gt;.4"1,:v..'n'

. ”w

‘

September 7, 1967
Dr. Louise Speck
CNRC

St. Eiizabeth's Hospitai
Washington, 0.6.
Dear Dr. Speck:
EEG

As I suggested in May, my iabaratory for quantitative
now operationa] and I would be pleased to have you
us.on your next tour through ﬂew York. The laboratory

is

visit

is in the Department of Psychiatry offices at

at the corner of Fifth
369—7900

Ext. 245.

Avenue.

I

5

can be reached

East

at (212)

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:kp

102nd

St.

.~

.-..

�</text>
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"H,

u.

:wn-wﬁ’r'WW-JJVIAJ'I- ‘4“ it?"

w

'iiﬂY'rWN'mWﬂW‘K\.u~wn'

-\.,,.~u-m.‘,~&lt;:r—mum-v map-a7.— ew‘

."v- A-‘dw‘ﬂl""'(.

...u~wgu m. w-u.~...r—w-moron» -';--F's&lt; mm 1;

Ont-".7

.—-\
wo'wt-ﬁrq'pvmrw'

inhuman.

,rv-

September 8, l967
Dr. Heinz E. Lehmann

Clinical Director

Douglas Hospital
6875 Lasalle Blvd.v
Verdun, Quebec
Canada
Dear Heinz,

'.»'Y“',

w-

rm

n‘3“

.stwiw-r-c'mrmmnl‘vmmynt

n
an

mm

w-n:

h":€-I«KW

I am grateful for your kind reception of the suggestion
that cyclazocine be discussed at the antidepressant panel. The
provisional title is "EEG Patterns Relating to Clinical Anti~
depressant Activity."
I would plan to review the EEG profiles of the known antidepressant drugs, describe the profile of cyclazocine and then
give an up-to—date report of the clinical studies of cyclazocine

as an antidepressant.
I

will try to

as requested.
My

have a copy of the paper to Dr. Hittenborn

best regards.
Sincerely yours,
Fink, M.D.
ProfesSor of Psychiatry

Max

HF :

kp

a!

a‘ “v.

.--~r—.

.4l.""

,—«~ ~

.

.m-

—.

hm

.1

-

l,

nu,

�</text>
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                    <text>”may?

,—

-‘

.........,.

y«"1'w~‘~w.14\~

‘. \wxr (m7. -7».

.

——,v.y.,.

_

”no—pm...-

September 8, l967
Dr. A. Arthur Sugenman

Chief. Investigative Fsychiatry Section
Eureau of Research in Neurology and Psychiatry
c/o ﬁew Jersey Neuro~Psychiatric Institute
Box

000

Princeton,

New

Jersey 08540

Dear Arthur,

Enclosed is the application and

corrections

a

set of suggested

which have been added to the xerox copy. Please
note the corrections in the eqiipment and supply costs.

Please call

me

if

there are any questions.

Good luck!

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MFtkp

'
V

&lt;muvgruv

�</text>
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                    <text>r“van-w n m;W
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Mrs. Mina ﬁatheson

Missouri Institute of Psychiatry
5400 Arsenal Street
St. Louis. Missouri 63l39
Dear Nina,
few visits to St. Louis,Dr. Itil worked me
so hard that I had no chance to visit you. Houevor. I did
meet Don Sundland and was pleased to hear of your project.
During

my

Recently Jovan Simeon shared with me one of your monthly
envelopes and I was pleased to find at least four articles
that I had not seen before and which were of further interest
to my present program. Would it be possible to extend your
service to an ax~Missourian7
My

best regards.
Sincerely yours,

via".

-.

'1er;

~4i—O‘J

Fink, M.D.
Professor of Psychiatry

Max

m

"-*'-"'“-Ww&gt;i

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September 8, l967

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                    <text>September

ll.

1967

Krohn~Hite Corporation

580 Massachusetts Avenue

Cambridge, Massachusetts 02l39

Gentlemen:

are anxious to get a set of filters which may be
suitable to use for the modification of EEG signals before
analysis. Would you kindly send me a cepy of your catalog
describing your line for this purpose and the name of your
closest representative in New York?
He

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>September l2. 1967
Research Fellowships Sect1on
Behavioral Sciences Training Branch
National Inst1tute of Mental Health
5454.wisconsin Avenue
Chevy Chase, Maryland 20203
Gentlemen:
At the suggestion of the Chairman of the Department.
Dr. Alfred M. Freedman, I an writing on behalf of a resident
physician who is now in his third year and to whom we would
like to recommend the Mental Health Research Development
Program. We would appreciate an application kit and the
instructions for submitting an application. It is my under~
standing that either Dr. Freedman or I w1ll act as sponsor
and the candidate, Dr. Arthur Zaks,w1ll be CGMpleting his

resldency training in June of l968
Thank you

for your cooperation.
Sincerely yours.
'

Mszp

Fink. M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>September l2. 1967
Miss Georgia Gorian

University of Minnesota
6908

l4th Street,

South

Minneapolis, Minnesota 55423
Dear Miss Gorien:
Thank you very much

interested in appointing

for your letter.

I am very much

an additional EEG technician. I
know of Dr. Torres' work and would be pleased to consider

your application.
New

I

Enclosed

is

application blank from the
College, and if you will send it to me,
reviewed by the personnel staff.

York Medicll

will

have

it

a formal

please indicate in the application your
permission to call one or two references.
Would you

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

MF:

kp

�</text>
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                    <text>September 13, 1967
Dr. Aiain Sanseigne

Associate Ciinicai Research Director

E. R. Squibb and Sons
Georges Road
New

Brunswick,

New

Jersey 08903

Dear Alain,

Enclosed is the latest reVision of the depot fiuphonazine
study as changed by us on Saturday. Please see page three.
I enjoyed being with you.

My

best regards.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MszP
GﬂC.'

�</text>
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                    <text>September 13, 1967
Dr. Edward Woodward, Jr.
Robins Company, Inc.

A. H.

1407 Cummings Drive

Richmond, Virginia 23220
Dear Dr. Woodward:

for your letter of September 8.

I think your
in
the protocoi for the investigasuggestions regarding changes
tion of fenfluramine are most heipful and acceptable. Piease
alter the protocol and send me a copy.

Thank you

Many

thanks for your cooperation.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                  <elementText elementTextId="102325">
                    <text>September l4, 1967
Dr. Charles Shagass
Temple University

Department of Psychiatry
Philadelphia, Pennsylvania
Dear Charlie:
I didn't forget your request but couldn‘t find this
reference to Ormsby until this minute, since my files are
still chaotic at home. The preper reference is: Drmsby, J.F.A.
(l96l) Design of numerical filters with application to missile
data processing. J. aaa. comp. mach. 8, 44D~466.

join

Turan has
him

in his

told

me

of your discussion and perhaps
you at the end of the month.

visit to

Please thank Clara for
regards.

an

excellent dinner.

My

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

I

will

best

�</text>
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                    <text>September 16, 1967
Dr. Lothar B. Kaiinowsky
115 East 82nd Street
ﬂew York. New York
Dear Lothar,

Enciosed is a

draft of the grant application.

I yould

and make any corrections or
if
suggestions. I wili caii your office on Tuesday or Wednesday
to make an appointment to meet with you.
be

grateful
My

you would read

it

best regards.
Max

Fink,

M.D.

Professor of Psychiatry

Mﬁckp

�</text>
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            <elementTextContainer>
              <elementText elementTextId="30472">
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                    <text>September 16, 1967
Dr. Hilliam Triebel

Gracie Square Hospital
420 East 76th Street
New

York.

Dear Dr.

New

York

Triebel:

Enclosed is a draft of the grant application for the
preposed study program at Gracie Square. I would be grateful
you and/or Dr. Ross would read this and we can discuss it
if
when we meet. I will call your office on Monday if I haven't
heard from you sooner.

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

MF:kp
ENC .

�</text>
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                    <text>September l8, l967
Dr. Michael C. Barry
Assistant Medical Director

white Laboratories, Inc.
Kenilworth, New Jersey
Dear Dr. Barry:

Both Dr. Itil and I are grateful for your consideration
of our request to undertake a study of fluphenazine in high
dosage in the populations in Istanbul and St. Louis. Your
willingness to file the necessary forms for an IND with the
Food and Drug Administration will be most helpful.
Our estimate of the supplies necessary to undertake th
study in Istanbul is as follows: for 20 patients, l0 weeks
observation at 400 600 mom/day will require 700 gms
fluphenazine. To provide for loss and drop—outs we will
ask a supply of lOOO gms.
—

best form would be in liquid concentrate, at the
palatable concentration, but not less than 20 mgm/cc.
the
concentration
If
is 20 mgm/cc, the amount will be 50 liters.
The

maximum

If tablets are more feasible, then 50 and 100 mgm tablets
should be considered, and the supply requested would be 3000
tablets of 50 mgm and 7000 tablets of l00 mgm.
discussed, we will try to obtain the funds necessary
for this study by diversion from other study programs, but this
source is limited, and we would ask White Laboratories to
consider an additional grant-in-aid in the amount of $l.000.
As we

Thank you

for your consideration.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

cc:

Dr. Itil
Dr. Polvan

�</text>
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                    <text>September 26, 1967
Dr.

Philip

8. Bradley

Center for Advanced Study in the Behavioral Sciences
202 Junipero Serra Boulevard
Stanford, California 94305
Dear

Philip.

Congratulations on your opportunity to study in California.
the opportunity fulfills your expectations, for it has
been spoken of most highly by so many scientists who have preceded
I hope

you.

I am writing to obtain some up-to-date information regarding
the book "Anticholinergic Hallucinogens.” Are all the galleys
and page proofs approved? If not, are there any further page
proofs that should be checked?
_

Is there anything else that has to be done? Or, am I to
that the editorial work is completed and we are merely
awaiting the publishers details?
assume

Incidentally, I have interested Dr. white in a study of
an anti-narcotic, cyclazocine, and hope that he will have this
work completed before he joins you in England next year.
My

best regards.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

Mszp
P.S.

If

you have a few minutes, please

(212) 369v8488.

call

me

collett at

�</text>
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                    <text>September 26, l967

Division of Research Grants
Public Health Service
.

Bethesda, Maryland 200l4
Gentlemen:

are anxious to apply for a U. S. Public Health
Service Grant and would request two application Forms PHS-398.
We

May we also have a copy of the supplemental instructions
for "Grants to Institutions Outside the U.S.“ and for program
projects and centers?

Sincerely yours,
ﬂax Fink,

”.0.

Professor of Psychiatry

Mszp

�</text>
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                    <text>s.»

L

E

E

is

E

September 26.

erw‘r—w'”

qﬂywrn

1&amp;6?

Hr. Stefan Began
Senior Research Associate
8epartment of Medical Investigation

Inc.
Jersey 07118

Hoffmann~La Roche

.w

”RF-WW

iWA’c-ﬂfv-

Nutley,

ﬂew

ﬁear Mr. Began:

—'

,,,,

_

r-Ht,‘

«

In order to continue our teaching program would it he
passible fbr you to send as 5,000 capsules of Librium placebos.
25 mg each?
.

«awn-mun

Many

thanks.

—!w-wr‘

Sincerely yours,

1w»

nw—v‘rru,

gamma-u

Max

,

Fink, H.D.

Preféssor of Psychiatry

k?

wwwu

mww—u— .7"

"3v”

11

L

«r

�</text>
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                    <text>September 27, l967
Dr. Robert L. Kahn
Department of Psychiatry

University of Chicago

Illinois

Chicago,

Dear Bob,

After a hiatus of eight years, I would like to undertake another study
of convulsive therapy. The recent modification of multiple monitored ECT
and unilateral ECT have stimulated my interest. while we have only a few
cases in treatment at Metropolitan Hospital, I have been fortunate in
obtaining the support of Dr. Lothar Kalinowsky and the staff at Gratie Square
Hospital and would like to undertake this study at that institution.
writing to you today to obtain your permission to include you
among
list of consultants whose advice I may wish to call upon as
we become involved with the details of this project. As you may guess
I am applying for support from NIMH and would like to make this a
definitive study involving many of the suggestions which were made
during our active days at Hillside.
I am

the

May I

have your permission?

Incidentally,

and I did so with a

recently invited me to give a talk at Hillside
great deal of enthusiasm. I found the hospital unchanged.

Hal Esecover

Pollack and

Lurie were old faces in the audience. The
interested in the topic which was “Computers
in Psychiatry." I visited the laboratories and was surprised to find our
old tape recorders, the apparatus built by Eric Karp and many of the tapes
which you had made still on the shelves. The EEG laboratory now has a second
machine and they are particularly involved with a detail ofihe EEG known as
Mitten patterns. There is much talk of building a research building and I
was surprised to hear that our old plan had been puled out of the files and
an application resubmitted to NIH for support at the same level as we had
tried eight years ago.
Don

Klein.

Max

residents were bright

Abe

and most

I trust that Dan Freedman was kind enough to extend my regards. We
met some months ago in Washington and had a delightful discussion of your

programs.
My

best regards.
Sincerely yours,
Max

Fink,

H.DD

Professor of Psychiatry

Mszp

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                    <text>September 27, 1967
Dr. Paul Blachly

University of Oregon School of MedicinePortland, Oregon
Dear Paul,
Thank you very much for sending me a capy of the
proposed
symposium at the forthcoming APA meeting. I hope that the
Program Committee will welcome this suggestion and I look

forward to participating.

It has been almost eight years since I participated in a
study of convulsive therapy, but your suggestions for HMECT and
the enthusiasm for unilateral ECT has stimulated me to under~
take another ECT study project. In my present facilities at
Metropolitan Hospital, the number of cases treated with ECT
are quite few and I have sought the cooperation of Dr. Lothar
Kalinowsky to study cases at one of New York's largest treatment centers. Gracie Square Hospital is well known as a center
ECT.
for

would like to obtain some support from the National
Mental Health and in doing so I would like to be
able to call upon you and Dr. Kaelbling as consultants. As
the originator of MﬁECT, I know of no~one more qualified to
advise us in the most satisfactory method applying this technique.
We

Institute of

May I have your permission to include your name
among the
consultants for the study ITheoretical Clinical Studies of

Convulsive Therapy?”
Many

thanks.

My

best regards.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

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                    <text>September 27. 1967
Dr. Werner P. Koella

Senior Scientist

for Experimental Biology
Shrewsbury. Massachusetts 0l545

The Worcester Foundation

Deer werner,

Enclosed is a final copy of the paper called “EEG Patterns
of Cyclazocine, A Narcotic Antagonist.“ which has been revised
following your suggestions. I believe this is much clearer and
I have taken the liberty of bringing some of the experiences
up-to~date.
I have withheld the
I believe the story

me.

satisfactory.

My

figures because none have satisfied
is clear as presented and I trust

The other report for the l967
best regards.

ACHP

will be ready shortly.

-

‘

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp
BBC.

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                    <text>September 28, l967
Dr. William R. Tabor
Director, Medical Research
A. H. Robins Company

l407 Cummings Drive

Richmond, Virginia 23220
Dear

Bill,

Enclosed is a protocol for a study of Repoise - syrup
which has been submitted to the appropriate committees for

expect that this will be obtained within
a month. By that time, I will have had the chance to discuss
the protocol with my full staff and the study may begin in

approval.

early

I would

November.

.

If this protocol is satisfactory,

and as soon as you
have submitted
to the FDA, please call me and we can
discuss the supplies that will be necessary.

it

Thank you

My

for theoopportunity to consider this study.

best regards.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>I». wvu

«am--

September 28, l967
Dr. Robert P. Nenno
Medical Director
New

Jersey State Hospital
New Jersey 07746

Marlboro.

Dear Dr. Nenno:
I have read the information which
you made available
me
regarding the Marlboro State Hospital with a great deal of tointerest.
I have discussed this research
opportunity with two of
former
associates at the Missouri Institute of Psychiatry. Dr.myNafi Kiremitci
has indicated an interest in this position and may write to
you

separately.

I met Dr. Kiremitci when he was an
assistant in
York State Psychiatric Institute in l96l. He psychiatry at
returned
Turkey to complete his military duty and was appointed to the to

the

New

Missouri

Institute of Psychiatry in July l965.

He has been actively involved in the
research programs there.
especially in the studies of new compounds as they effect
behavior
of the severe mentally ill. He has an experience with populations
similar to those at the New Jersey State Hospital.

has recently completed the requirements for licensure
and is scheduled for the examinations of the American
Board of Psychiatry at their next meeting.

in

He

two

states

I believe he may be helpful in your program and
trust that he
In the interim, a copy of his curriculum vitae

will write to you.
is enclosed.

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                    <text>September 28. l967
Dr. Leo

Hollister

Associate Chief of Staff
Veterans Administration Hosﬁital
Palo Alto, California
Dear Leo,

to take this opportunity to thank you for your
my associate, Dr. Jovan Simeon. He has returned
from his visit to California quite enthusiastic about the work
in your laboratory.
I want

hospitality to

recently been asked to consider a study with
I recall that some years ago you were quite
enthusiastic about this drug and I would be grateful for
any reports that you may have prepared in your studies.
I have

oxypertine.
Many

thanks.
Sincerely yours,
ﬂax Fink. M.D.

Professor of Psychiatry

MF:kp

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                    <text>2:
A

'-:;&gt;‘"-‘

7».

-v-'

—v.

:.-,-;-—.n-

;7

warmer-gr:-

September 28. l967
Dr. Nafi Kiremitci
8396 Big Bend Boulevard

webster Groves. Missouri 63ll9
.

Rafi.

Dear

discussed your request Iith our chainsan, and
at the present time to make an additional
appointment within this department.
I have

it not possible
‘

it

you requested. I have made a number of calls on your
behalf and I believe that an appointment may be available at
the New Jersey State Hospital at Marlboro under the supervision
of Dr. R. P. Henna. He has an extensive research program under
development and is seeking an aggressive research leader. The
programs are affiliated with the new programs at Rutgers
University Medical School! I have written to Dr. Memo on your
behalf and suggest you contact him. Some data on the hoSpital
follows.
As

My

regards to Betty.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

cc:

Dr.

Itil

�</text>
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                    <text>September 28, 1967
Mr. Dona1d B. Cheetham,

Jr.

Research Associate
C1inica1 Investigation Department
Smith K1ine and French Laboratories
5500 Spring Garden St.
Phi1ade1phia. Pennsylvania 19101
Dear Don,

the research circu1ar on SKF 14336 with a great
interest. Whi1e I think the study is appronriate, I do
not be1ieve that the target popuiation that is 1isted in the
protoco1 can be made avai1ab1e at our hospita1 for a number of
months. For this reason I wouid ask to pass.
I have read

dea1 of

Thank you very much for the opportunity to read this information
and I hope that we wi11 have an opportunity to participate in another

study.

My

best regards.
Sincere1y yours,

Max

Fink. M.D.

Professor of Psychiatry

Mszp

�</text>
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                    <text>/
2mm,0" new
ﬂ’mv'mwx’wnwur

—“"'5‘"

mmmm‘"

September 28, 1967

,

Dr. Lothar 3. Kalinowsxy
115

New

East 82nd’5traat

York, New

ank

10028

Delr Lothar,
Enclosed is a copy cf the appIication for support of the
study of ECT at Gracie Square Hospital. I want to thank you
again for your help and 100k forward to undertaking this study.
My

best regards.
Sincereiy yours,
Fink. M.D.
Professor of Psychiatry

Max

MRkp

enc .

A

&lt;

�</text>
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                    <text>September 28, 1967
Dr. William Triebel
Medical Director

Gracie Square Hospital
420 East 76th Street
New

York.

York

Bill,

Dear
and

New

Enclosed is a copy of our application as submitted to
five additional copies without the financial pages.

NIMH

this proposal to the
appropriate committees of Gracie Square Hospital for their
review and approval.
I

would appreciate your submitteng

I want

cooperation.

to take this opportunity again to thank you for your
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:kp

enc.

�</text>
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i

camber 3,

1967
‘

Miss Yulmen Cig

Missouri Institute of Psychiatty
5400 Arsenal Street

.

‘

A.

St, Louis, ﬁisseuri‘63139

,

,

IDear Yulmen.
.

Would you

and obtain
I need the
may

please

Also. ask for

wish.

of the enclesed figure.
glossy prints from your photographer.

make up a graph

eight
prints as rapidly as
5 x 7

But

2

x 2

those-is

you can

get

them to.me.

slides for ﬁe and any that your uncle
n9 rush an the slides for me;
‘

figure the three graphs should be made 0f distinctive
but
at the points marked .01, .05 and .001 please put in
tape,
some symbol like a triangle, square or star.
In the

Please bill
which

me

at the

New

York Medical

Incidentally, I will be sending you
there will be no rush

College.

some

others about

Sincerely yours,
ﬂax Fink, M;D.
‘

liF: kp
Hi!

Kathy

Professor of Psychiatry

-.=~-- v,

awn»...

I'nn-' '~A&lt;{1:u-v‘- 7...“.

�</text>
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                    <text>.

Octaber 4, 1967

ﬁr. Richard P. white
Associate Professor
The University of Tannessee
ﬁepartment of Pharmacology

ﬁemphls, Tennessae 38l63
,A

_

nwvar.

:“Nv-Nw'wxlsn

Bear Dick,
With regard to the buéget requést 9f expenditures on the
cyclazocine project, 1 do net thlnk that we are able to approve
either equipment or travel since these are RIB rastrlcted
categories. The funds allocated are for “Cansultatlon” and
that these may be expanded as consulta-’
it is my understandingmembers
tion fees for you or
of the staff of the University of
Tennessee or may be transfernd to other unllm1ted categories.
such as personnel or supplies.
Inﬁofar as our travel funds on this project are restricted
and limited we are unalla ta apprave this speciflc request.
-

~,&lt;r-a—p.-wv:mv.wv

‘wvt‘m‘:

3&amp;va

.

.
...,

My

map-FIv-wvti'm'qv

ﬁbuld you please submit a revised budget including only'
allowable items.

‘m'

V

Good

,

luck!
Sincerely yours,
Fink, $.8.
Professor of Psychiatry

Mai

.

ﬁF:kp
ccﬁ

4

.1

.

.

.mxa'e-wr.

Dr. Freedman
Dr. Morgan

‘mw'mv

wwm' u an

.,

�</text>
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                    <text>'=

&gt;

‘

~«-1vv.

{w-W“4;_‘r‘_‘1..

_

_

_
.

”1

'm
-

,

'

W,

‘W‘

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J- W!‘8'V,*\w1‘l¢'m;7~xzin:.

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October 3, 1967
Dr. Bernard C. Giueck

Institute for Living 690

Hartfordglgonnecticut
Dear Buzz,

Enclosed are two copies of our report “Digitai Computer
Research.“ The figures
Analysis of the Human EEG in Psychiatric
soon as
are incompiete but glossy prints will he sent to you as
I

them from the photographer.

get

mcawor

wan-WA

83070

Thank you very much

"M

for this opportunity.

My

best regards.

‘Sincereiy yours,

Wm"

c-

Fink. H.D.
Professor of Psychiatry

,.

Hax

any“.

..,.__

,7

err-1mm"

MF:kp

�</text>
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                    <text>October 4, l967
Dr. T. P. 5. Watts
Geigy Pharmaceuticals

Ardsley.

New

York 10502

Dear Paddy.

Enclosed is the FD 1573 for ketimlpramine and an additional
copy of the proposed protocol. As we discussed. I would like to
have your comments,

I have already set into motion a program for the classifica«
tion of patients using the Hamilton Rating Scale.

I enjoyed lunch.

My

best regards.
Sincerely yours.
I

Fink, rm.
Professor of Psychiatry

Max

Mszp

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                    <text>October 4, l§67
Dr. Joseph 6. Bird

Director, Division of Clinical Research

Sterling~winthrop Research Institute
Rensselaer, New York l2l44
Dear Joe.

Enclosed

institutions.

is

a proposed protocol

for the collaborating

In addition, the modification of our protocol is also
enclosed and I would be grateful for any criticism that you

have before I implement this. If the protocol is
agreeable to you, would you be able to supply us with

may

cyclazocine capsules with .25 mg cyclozocine in a pink
capsule as enclosed. I can obtain the imipramine from
Geigy directly. If this is not satisfactory, would you
be willing to obtain imipramine from Geigy and make up
matching capsules of 25 mg imipramine and .25 mg cyclazocine.
Sincerely yours,
Fink, M.D,
Professor of Psychiatry

Mex

Mszp

�</text>
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                    <text>.r-ws

,

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9cm; 5,7196;

Dr. AITen Raskin

Research Psychaiogist

a

APsychapharmacology Research Braﬁdh
National Instituta of Manta] Health
.5454 wisconsin"Avenue~f"~
Chevy Chase, Maryland 20203

‘

‘

;

Eear A11en,'
.I want to thank you far your supportfand
intérest.dur1ng
the recent cyclazocine conference in Reassalier. I hope that
:this compound-can be assayﬁd by the ﬂIME study groups. It
would be-most.hé1pfu1 ta know if'the prasent trantment models
n_£an indeed be faiated to their EEG profiles, and if a new group“
of antidepresSants exist in the antinarcqtics.

l

I.havg written a suggested prgtccal, and have sent the
original to Br,.Jaseph Bird 9f Sterling-Hinthrop.’ He is
particuiar3y interestgé fﬁ‘this°eva1ugtien.and has agreed to
organize these Speciai stadieS; Wouidryou‘srﬁtique this
suggested proposal and eithér write Gr 6&amp;1} him with-your
suggestions? If~a proposal can be agreed to, I-trust
will be abIe to BSstt us in the necessary arrangementsyouwith
the study grsups;

,gl

.

'

;

‘Again,”my thiﬂkSé .~

Singeve}y yourSs

"
:

mm
cc:

i‘

$

'

’

-Dr.'81rd

I

Fink, ﬁQD.
‘Prafessor of Psychiatry
Max

‘
.

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�</text>
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                  <elementText elementTextId="102307">
                    <text>mwrnaviawlﬁ

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7r0€tober 6, l967
Mrs; Nina Mathesdn, Librarian-l
Missouri Institute of Psychiatry
5400 Arsenal Street
St. Levis. Misscuri 63l39

'

'

Dear Nina.

I.was very pleased to receive your letter. and I found a"
review of the cancapt lists most interestthg.
,The concept

numbers and titles that reflect my present interests
are
enclased. and except for a fnw places where l was unclear

ihcluded each descriptor) I believe as
these‘
are‘sufficiently specific to limit'the number of titles which
to distinctians (so

.

will

be

I

sent;-

.It is clear that this system is dependent on the
of the coders. and you must be callecting'valuable dataability
as to
the qualities necessary for subh‘work. QOur own system broke
down when we required the
descriptors frOm the
and
than checked them. Nevertheless I.look ferward scientists
to seeing the
output from year system.Since returning to New York have deleted my timé to
'reestablishing the computer~EEG facility (it is now operational
and a second EEG laboratory will be completed this month);
the
clinical research units (there are three ~ an 0P8 unit fer new
drugs; a 25 bed in-patient unit for narcotic addiction; and a
25 bed unit for acute mentally ill and new
treatments); and the
psychopharmacology teaching pregram. ~I have had no time to re»
establish the library programs although we have the HIP—EEG
cards in duplicate and I hepe to put a programmer on the problem
wI

.

soon.

'

‘

,

it

~

'

.

L

W'in-uci-WJHU'

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“mp-..“r-yuv‘ug- vcn:«rwmwm: nu. ~muvwra-m1.

.

arm"

l“

Mrs. Nina Matheson

«2-

October 6, 1967

Having the Academy of Medicine around the corner has been
of help. I now have a iibrary card that permits me to visit in
the evenings. But time is stiii short - even less than in Missouri
and so I have to depend on the journals that cross my desk, and
now, to your 591.
Many

thanks again.

And

give

my

best regards to

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

Mlep

Don.

~

�</text>
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                    <text>1w

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.

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‘v—wu—“wyvzr.v.’--&lt;r‘c--~~-~4i-nw-rn—v',vw7..vv'v‘w—wr‘vww-v—

-1

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,

October 9, 1967
Dr. Antoine Remand

Hﬁpital de

la Salpétgém

47, Boulevard de
75-«Paris (13%)

Dear Hr.

l'fbpital

- Frame

W:

I reply to your letter of October 3, mgardm an Intermtioml
Courseontm occasion ofthemxt IntemtionalEEBMee
, Ian

watims

pleased to send you my
for the titles I mulcngOSEfQP
the sections of a modem book on Em. Incidentally, I enjoyed this
exercise for it famed me to think of our field in very general team.

I trust these are helpful am yau My be assured of the
oollabomtionandsupportofmwﬂaemofmylabomtoryin
your efforts.
Sinner-$13;

yams ,

Pink, {4.1).
Professor of Psydziatry

Max

Mfzkp

s

�</text>
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                    <text>September 5, l967
Dr. James H. Satterfield
Gateways Hospital
189l Effie Street
Los Angeles, California 90026
Dear Jim,

pleased to receive your letter for I have known of
Gateways Hospital for some years and am delighted that this
fine institution will have your support. Knowing of its
similarity to Hillside Hospital, I was pleased to discuss the
development of research programs with the Ziskinds on many
occasions during the past few years and was most encouraged
by their forward looking point of_view. Good luck!
I was

I am pleased to enclose a few of the available preprints
of studies recently completed. This work was done at the
Missouri Institute of Psychiatry using the IBM l7l0 a l620

system which

I

established there.

I do not know of anyone using a link computer successfully
in the analysis of EEG signals except its widespread use for

averaging evoked potentials.

Please give

my

next you see them.

personal regards to both the Ziskinds when

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

Mszp

�</text>
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                    <text>—.-&lt;-—'w

,

kg
,s

September 5, l967
Mr. Harold Mehling.

Psychiatric Progress
3 west 57th Street
New

York,

New

York

Editor

l00l9

Dear Mr; Mehling:

that
is a

Thank you for your letter of August 29. The presentation
I will be making at Hillside on "Computers and Psychiatry“

of the report published in the recent textbook of
psychiatry puhiished Iy Freedman and Kaplan, Williams and Wilkins.
Additional information is being published in a volume by
Kline and Laska. A copy of this article is enclosed.
summary

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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i33

September 7, 1967
Dr. Louise Speck

CNRC

St. Elizabeth’s Hospital

Washington, D.C.
Dear Dr. Speck:
EEG

As I suggested in May, my laboratory for
is now operational and I would be pleased

visit

quantitative
to have you

as on your next tour through New York. The laboratory
is in the Department of Psychiatry offices at 5 East 102nd St.
at the corner of Fifth Avenue. I can be reached at (212)
369-7900 Ext. 245.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>September 8, 1967
Mrs. Nine Matheson

Missouri Institute of Psychiatry
5400 Arsenal Street
St. Louis. Missouri 63l39
Dear Nina,
During my few visits to St. Louis,Dr. Itil worked me
so hard thtt I had no chance to visit you. Houever, I did
meet Don Sundlend and was pleased to hear of your project.

Recently Jovan Simeon shared with me one of your monthly
envelopes and I was pleased to find at least four articles
interest
that I had not seen before and which were of further
extend
be
your
possible to
to my present program. would it
service to an ex-Missourian?
My

best regards.
Sincerely yours,
Fink, n.0,
Professor of Psychiatry

Mex

Mszp

�</text>
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                    <text>September 11. 1967
KrohnaHtte Corporation
580 Massachusetts Avenue

.

Cambridge, Massachusetts 02139
Gentlemen:
We are anxious to get a set of filters which may be
suitabie to use for the modification of EEG signa1s before
analysis. Hou1d you kindly send me a capy of your catalog
describjng your line for this purpose and the name of your
closest representative in New York?

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>J‘

September

l2.

1967

Miss Georgia Gorian

University of Minnesota
6908 14th

Street. South

Minneapolis, Minnesota 55423
Dear Miss Gorian:
Thank you very much

I am very much
technician. I

an additional
of Dr. Torres' work and would be pleased to consider

interested in appointing

know

for your letter.

EEG

your application.
Enclosed

New

I

application blank from the
College, and if you will send it to me,
reviewed by the personnel staff.

is

York Medicll

will have

it

Would you

a formal

please indicate in the application your

permission to call one or two references.

Sincerely yours.
Fink. M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>September 26,’l967

Divlslon of Research Grants
Public Health Service
Bethesda. Maryland 200l4

Sentlemen:
He are anxious to apply for a U. 5. Public Health
Service Grant and would request two application Forms PHS~398.
May we also have a copy of the supplemental instructions
for “Grants to Instltutlons Outside the v.5." and for program
projects and centers?

Sincerely yours.
Fink. H.D.
Professor of Psychiatry

Max

HF

:

kp

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                    <text>'

"-w

H

-

v" - ‘lv

.

~

4—,

‘N

7.:

..;

~m.1—q".

1"

-

,

.

‘IVIV‘u-rrn‘w—umlrrr‘»wanvvb 7e17,“.

m...-.m..‘.,...,_,,:m._w..:,_._. _._. ..

.

W

...

.

_.

rm."

w-xu-u-

n

emvnvv-mnmw..,.m_,

September 27, l967
Dr. Werner P. Koella

Senior Scientist

for Experimental Biology
Shrewsbury, Massachusetts 01545

The Worcester Foundation

Dear Werner,

Enclosed is a final copy of the paper called

Patterns
of Cyclazocine, A Narcotic Antagonist,” which has been revised
following your suggestions. I believe this is much clearer and
I have taken the liberty of bringing some of the experiences
"EEG

up-to-date.

I have withheld the
I believe the story

me.

satisfactory.

figures because none have satisfied
is clear as presented and I trust

other report for the l967
best regards.
The

My

ACNP

will be ready shortly.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp
enc.

�</text>
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                  <elementText elementTextId="102299">
                    <text>October 3, l967
Dr. Bernard C.

Institute for

Liv

-

HartfordiLConnecticut

f0 z) ﬂlf/‘g/

«M 76:5

Dear Buzz,
'

Enclosed are two capies of our report "Digital Computer
Analysis of the Human EEG in Psychiatric Research.“ The figures
are incomplete but glossy prints will be sent to you as soon as
I

get

them from the photographer.

Thank you very much

for this opportunity.

My

best regards.

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

Mszp

�</text>
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                    <text>4

z,

ill

October

..

'W=W'r-w-vmwuwv

'

9

, 1967

Dr. Antoine Renond

Eﬁpitel de

la Salpétlém

w , Boulevard

75~Paris (13¢)

do

l'lbpital

- Hence

DearDr. Renard:
an International
I reply to your letter of October 3 , regarding
EEG
Meeting, I am
Course on the oocasim of the next International
would
choke for
pleased to send yw my euggestime for the titles I
BEE.
this
enjoyed
I
Incidentally,
the sections of a modern book on
toms.
in
general
Wise for it foroed me to think of our field very

I trust those are helpful and you my be assured of the
oollabomtim and support of the members of my laboratory in
your efforts.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

Pﬁzkp

�(11.4.,

a : vow—'1» Ivr“~‘-'uc--RTW'-u‘.'1

n-‘v-vrwr'v-aun

,

-:I.v.‘-r'.

!
From:

w-v-v-v-ru-v

»—:--

WMIMI'I—W-A»

.m-

A

r;

«mm

.

“—47 vrwja'fHWV'vl.

SUGGESTED TOPICS FOR COURSE OR TEXTBOOK OF EEG

Fink, M.D.
Professor of Psychiatry,

Max

New

York Medical College, U.S.A.

History of

2.

Technical Aspects
a) Recording methods
Amplifiers
Noise vs. Signal
b) Analysis Methods
1. Visual pattern, frequency

EEG

Theory of Etiology of Signals

—

2.

Electronic

Amplitude integration

frequency integration

3.

-

”Kr."

Pattern » Filters
Digital Computer
Power spectral-density
Period Analysis

Amplitude

.er.~—-w~m—

“"‘I'V'VWMVF‘WV

:

1.

-,&lt;.-.

m

'-‘7~"r'§;\-'1"I-‘-"‘~‘ranvvruwvr;m“uuva—nwa~saw-

,|’

N...”—

~Y-nrs'

n

Pattern

a.

Spike Counts
Sleep
Special Devices
Averaging Computers

prosco
SourceJEgnk

3.

Neurophysiological Bases
a) Single cell and axonal data
b)

arousal mechanisms

c) Depth recording data in
d) Biochemical changes
1.
2.
3.

u.
u.

Maps

EEG

man

Oxygen

Acid~base
Glucose

Salts

and Function

a) Alteration with altered consciousness
1. Alertness, Sleep
2. Orientation
3. Delirium, Confusion
H.

Attention, Preparation, Set

,w -

ar'm

rlwqui‘v

.&gt;

....,. F'Va' w-r

,u-vwwnw‘w

v .-

�ww- ~www-Athww- W'.vI-w,&gt;.r'W'-u".‘“ﬁrm-m.“

a.

.su \pcﬂh‘v

.

«--

»»m~.q,y-m.

:"

.u

dawn...“- wu—uywm._....y,...‘.,.. "w”. .rm...

“m...

my;

‘w.

my...

.

.xga'v‘wﬁdrp-‘Ki

--(p—-

.-m.-...~ ~.,...-.»-.r.....~r. "um—n.» .

-2Hours

b)

Alteration with "Structural”
1.
2.

PHI-4

3.

Change

Seizures

Focal lesions (tunnr)

'I‘rauma

o) Alteration with Exogenous Toxics

l.

Alcd’xol,

2.

Psychopharmceuticala
a) 'I‘r‘anquillizers

narcotics, anti—narcotics

b) Hallucinogens

c) Sedativee
(31)

Others

d) Alterations With physiology
”ﬁrm-”w“.

"A

1.

Menetnmtion

2.

Sleep cycles

m

A

-

1
.-

5.

&lt;

www&lt;vwm»

Clinical Applications
a) Use in Epilepsy
1))

HRH

Use

in netwologywnemosurgezy

c) Use in clinical psychiatry
1.

6.

Diagnosis

- "Emotional

Developmental Aspects

a) Development with age in
1.
2.

1:)

..

:v-w—

.mvvmw-z—nmn

EEG"

man

General aspects - special
Areal differences

wave forms

Comparism among species
1.

Variations in pattem in relation to specie ' s heiramhy.

2.

Differences in drug response armng specie-s.

w.

�</text>
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                    <text>Wis-5+"

m

-n-'r-

‘

new:

W

October

9 , 1967

for Data Analyses

The George Washington University

Blanetxdc Iabomtmy

Roan 618

11% Nineteenth Street, NM.
Washington, D.C. 20036

map I!"

W:

are rm: involved in sattixg up a depression study
it mm be met helpful to have the Hamilton
Rating Scale. If this is available far Optical 83m, muld
you please send us 100 fans as soon as pmcticable?
We

few which

Many

marks.
Sincerely yours,
Max

Fink,

PM).

meeasor of Psychiatry

HEW

�</text>
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                    <text>wry—acr—
q
w.».=.~wmmv../mnw.,-- x I-K'»'
.

m

g:

'4

.. —,... mun-w.-s
1—9“7" .s'up». an“

. l

I

.
.
‘k-rwci.-1vr‘n.,-r&gt;".Pr"/W3‘rm
w
.

.

.

.

mummy-w mun-w, ‘w-wwr‘ ..‘ ‘~7’.«'-:~C_p-:qv~-ar«‘.(-3A"1IV'RMIVZ

"-ww:-r—;~v\'v-Y"ﬁYYn-“ww'ix‘

‘4,"

v

(m.

l,

October 10, 1967

.

-

V

.

~7‘
3r. R. Kaelbling
Associate Professor of Psychiatry
The Ohio State University
Department_of Psychiatry
.

7....

W.

V

430 west

“maven-v

.V

loth

Avenue
Columbus, Ohio 43210_

_

.

‘

{

~

‘Dear Dr. Kaelbling:

“VHF...“

has been some months-since we discussed Unilateral ECT
and-during the interim my associates‘and I have reviewed the
literature and decided to undertake a systematic study. Recognizing
that the populations available fer convulsive therapy studies in a
municipal hoSpital are limited; we have been most fortunate in
establishing a geod relationship with the staff at Gracie Square
HoSpitala This hospital is-a erivate facility with a very active
in—patient and euteoetient treatment program. Dr. Lothar Kalinowsky
has agreed to help_us in selecting cases both from his own popula~

It

v

-

»

y-Wpy-v-l

'M'J-

Mums

tion and from those of others at this hospital.

«7

«

WWVV

rv.‘

course, we reviewed your work carefully and were impressed
with the data presented in your unilateral studies. Gur'present
protocol calls for a comparison of unilateral (non—dominant) seizures
with bilateral seizures given at a customary_rate of three times a

~4\

Of

r

.714‘

-~..-

r:
:u

week.

Hurry-«w:

The

criteria for

change

will

be memory

.

tasks, quantitative

measures and behavioral scaless- If indeed the unilateral
seizures show lesser degrees of memory impairment and equivalent
of
clinical results, then_we would nape to undertake a comparison
and
the MMECT as described.by slachly, both in the unilateral

a“

EEG

-»~r

bilateral

modes.

"

'

‘

-.

Will be extending.both your work and that
of Paul Blachly.’ For this reason, and with the collaboration
sof'Dr. Kalinowsky, I would like to ask your permission to list
you as a consultant to this project. We have asked Dr. Blachly
and-he had'agreed to assist us. As you can guess, such a study
will be difficult to carry out with proper controls and we would
he encouraged if you would be able to assist us from your experiences
This will also give.us an epportonity to get to know more of your

,In this study

'

'

‘

we

experiences.

’

‘

say I_have your permission to
"'
this project?
'

My

1

.

best regards.

list you as's

consultant to

.

.Sincerely yours,
Fink, M.D.
Prefessor of PSychiatry
“

Max
L

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.

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          <element elementId="48">
            <name>Source</name>
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              <elementText elementTextId="30123">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                  <elementText elementTextId="105540">
                    <text>wry—acr—
q
w.».=.~wmmv../mnw.,-- x I-K'»'
.

m

g:

'4

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1—9“7" .s'up». an“

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I

.
.
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.

.

.

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mummy-w mun-w, ‘w-wwr‘ ..‘ ‘~7’.«'-:~C_p-:qv~-ar«‘.(-3A"1IV'RMIVZ

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‘4,"

v

(m.

l,

October 10, 1967

.

-

V

.

~7‘
3r. R. Kaelbling
Associate Professor of Psychiatry
The Ohio State University
Department_of Psychiatry
.

7....

W.

V

430 west

“maven-v

.V

loth

Avenue
Columbus, Ohio 43210_

_

.

‘

{

~

‘Dear Dr. Kaelbling:

“VHF...“

has been some months-since we discussed Unilateral ECT
and-during the interim my associates‘and I have reviewed the
literature and decided to undertake a systematic study. Recognizing
that the populations available fer convulsive therapy studies in a
municipal hoSpital are limited; we have been most fortunate in
establishing a geod relationship with the staff at Gracie Square
HoSpitala This hospital is-a erivate facility with a very active
in—patient and euteoetient treatment program. Dr. Lothar Kalinowsky
has agreed to help_us in selecting cases both from his own popula~

It

v

-

»

y-Wpy-v-l

'M'J-

Mums

tion and from those of others at this hospital.

«7

«

WWVV

rv.‘

course, we reviewed your work carefully and were impressed
with the data presented in your unilateral studies. Gur'present
protocol calls for a comparison of unilateral (non—dominant) seizures
with bilateral seizures given at a customary_rate of three times a

~4\

Of

r

.714‘

-~..-

r:
:u

week.

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The

criteria for

change

will

be memory

.

tasks, quantitative

measures and behavioral scaless- If indeed the unilateral
seizures show lesser degrees of memory impairment and equivalent
of
clinical results, then_we would nape to undertake a comparison
and
the MMECT as described.by slachly, both in the unilateral

a“

EEG

-»~r

bilateral

modes.

"

'

‘

-.

Will be extending.both your work and that
of Paul Blachly.’ For this reason, and with the collaboration
sof'Dr. Kalinowsky, I would like to ask your permission to list
you as a consultant to this project. We have asked Dr. Blachly
and-he had'agreed to assist us. As you can guess, such a study
will be difficult to carry out with proper controls and we would
he encouraged if you would be able to assist us from your experiences
This will also give.us an epportonity to get to know more of your

,In this study

'

'

‘

we

experiences.

’

‘

say I_have your permission to
"'
this project?
'

My

1

.

best regards.

list you as's

consultant to

.

.Sincerely yours,
Fink, M.D.
Prefessor of PSychiatry
“

Max
L

MFrkp&gt;

.

“q..-

,

nrJ-~9~vvvwv

~-'-'-P"|--'

�</text>
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              <elementText elementTextId="30111">
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              <elementText elementTextId="30112">
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              <elementText elementTextId="30113">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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              <elementText elementTextId="90335">
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          <element elementId="37">
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                  <elementText elementTextId="105539">
                    <text>October 18, 1967'

Senior Scientist

The Worcester

'

Emmatim for

3mm, WM 015%
Bear ‘W,
-

m
Ibeliewtlmttm'm
that you fave set up for theiswcial mm is sufficimtly
Wiveﬁmtitmymtmmqwmlyminﬁwtm
Perhaps the time which my be available may better
abated.
used to extend the fmlﬁr
WOW?
Them: you very mach

for your invitatim to‘msent

mitimwldetainmudymxpnh
'

_

'

be"

.

‘

1y.

yours,

*
rm?"

m
m, 9f Psychiatry
WEEW
‘Mcgo'

,

M3216"

cc:

the. 11:11

�</text>
                  </elementText>
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            <description>An account of the resource</description>
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          </element>
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              <elementText elementTextId="30102">
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                    <text>“w wﬁwn'rﬁwv.w-r,

October 10, 1957
Dr. Merton Wacmspmss

Chief , Psychiatry Services
Coney Island Hospital

Ocean and 81mm Pathways
meklyn, New York 11235

Dear Mort,

W

you very mach

for the invitation to visit with

you

onNovemberlé}. IMveputﬂﬁsinmycalendarandwilltr‘y
to arrive about 12:15pm.
The

title is fine,

even

if it is

a bit: pedantic Perhaps

a shoﬂar- title like "New Drugs in Psychosis" amiss the
8am infonnatim in telegraphic style. Again , my thanks for

your

invitation.

Sinoemly yams ,
Fink, PM).
Professor of Psychiatry

Max

MFﬂcp

.

mes-mm n- ..f—ww .Ar"‘r~l~'

.\

_

�</text>
                  </elementText>
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,

,

”up——

'Wwwmw—nwvw w- w. “.77"...—

_

w.-_....v

,_

v.__v ...._....._..._,.7..,....-_‘.-....W.__..v_..~.-N-..

"u.-. . _,__.. F..." ..._..... - s.» . s

.3

‘o

.

x

October 10, 1967
Dr. Paul Kay

'

l5 Canterbury Road
Great Neck, new York ll02l
Dear Paul,
Our discussion Sunday evening was most stimulating and
brought into focus the problems inherent in any teaching program
outside a medical training facility. Your suggestion of a survey
is a very good one.
'

with regard to the psychopharmacology sessions, it is apparent
that l have misjudged the tenor of the Society in suggesting that
a seminar serics of national experts be established.

suggestion of an evening to discuss problem cases
and one. but in rovioui
our discussion I find that I

Your second

is also

am

a

a possib e reiteration of the some misrather, therefore, not volunteer to load such

sspecia ly sensitive to

judgment. I would
a seminar.

If the

for such a session or
this expression is independent of a named participant
leader. then I would be willing to consider.an invitation from you
to participate. You should know. however. that there are other
competent psych pharmacologists in the Society, such as John Hhittior

sessions and

membership expresses the need

and Donald F.
You

'

«inn.

will understand that
to fail, if

announcement were

to participate.
.

Many

be less embarrassing if the
it wouldmade
independent of my ability
it were

thanks for your comments.

Sincerely yours,
Fink, H.D.
Frofessor of Psychiatry

Max

MF:kp

.

sm,

.7

�</text>
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w

,,. 7V,m.m,_wvtw.~..~.m-w.w_m_.w.,..m-«.‘nrwww.
.7

r“ nimvwrw.“

n

-w...

i

.

.

..

.

.

October 12, 1967

Arthur 6. LaMirande
Grune and Stratton
38l Park Avenue South
New York. New York

Mr.

Dear Mr. LaMirande:

Enclosed are the figures for the report "Digital Computer
Analysis of the Human EEG in Psychiatric Research.“ Figure 5
is still at the printers and will be delivered Monday and should
be in your hands by Tuesday.
Thank you

for your patience.
Sincerely yours.
Fink. N.D.
Professor of Psychiatry

Max

iii-”:94:
ENC .

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WW,

mm.

Gctober 13, 1967

yv‘y-wyw

‘I'w—v—n-g?

..

—'.

Mr. Arthur G. LaMirande

Bruno and
381
New

Stratton

Park Avenue South

York,

New

York

Dear Mr. Laﬁirande

Enclosed ﬁs Figure 5 and the legend for the report
"Digital Computer Anaiysis of the Human EEG in Psychiatric
Research."

n».

yr,

V”,

Thank you

for your patience.

m,

Sincerely yours,

41'

;-.»_uwnr—v»

uu-W.

.-

Fink. M.D.
Professor of Psychiatry

Max
-

”Wm

Mszp

�</text>
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                    <text>Irv»

rcg-m‘uw-«wswaqnm V‘v—v.r.c',u,vz—u

“r"...

W

.

,

,

.

,

~

»

.,

«'7

., m- .. ,...m.. w

vmv—

mmmw v...

m—w—mwp-w

October 16, 1967
Dr. T. P. 5. Watts
Geigy Pharmaceuticals

Ardsley.

.

-

new York lOSOZ

Dear Paddy,

discussed with you, we are planning to undertake a
comparison of Tofranil as the standard antidepressant with a
novel compound. cyclazocine. This study should be double blind
and in order to provide us with matched capsules, I am writing
As I

Geigy Pharmaceuticals to make available to us 600 mg
imipramine powder. If this is possiblc, I would appreciate your

to request

shipping this to:

Dr. Joseph 6. Bird

Director. Div. of Clinical Research
Sterlingowinthrop Research Institute
Rensselaer, her York l2144

protocol for this study is now being revised and I
will send you a copy of the definitive draft as soon as it is
The

completed.
My

best regards.
Sincerely yours,
ﬂax Fink, ﬁ.9.

Professor of ?sychiatry

Mszp

_.__.....__“_. ”WNW-m..." WW-

�</text>
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                    <text>WW-«nuanm

"zanww-hwu-oc

--..

a.

use

x..u.—..

“van-lawn“

-.

.

w

r‘

V"—ir-‘

'r-

\V-w.u_.._~,_m.w...

October 17 , 1967
Dr. Otto Schwartzkopf
Schnertzkopf Micmanalytical laboratories

um»-

Ara.»

'V—vn

56~19 37 Avenue

Flushing,

Tim‘a‘ﬂ

aw:

New

York

.375,-

Dear Dr. Sommacopf:

.5“,

discussed on the telephone, I am serxiingyou by
two
capsules, each presumably oontaiming mugs of
messenger
“Heroin Hal. (pure) Reorystalized. " We would like you to
As we

‘ew~u,n&gt;w—‘ITV

A

carry out such analyses of the denies]. and physical properties
of this compound as my be necessary to answer the following

y.w-vu¢rvwml¢uwkunpy~

questiOm:

is the purity of this sample (what percentage
of heroin does it contain)?

um...

What

Ms

note

is

for this catalysis.

.r,

an autlnrization

to bill us

up

to

$100. 00

“pm-v.1."

For your information, this sample was derived from a
govemsental agency and is part of a sample used in a study
pmgzm at this college.

“up-van

',.~ww,.,.,vr..~WWW.”

Thank you very Mich

a."

for yaw help.

.._

Sincerely yours,

‘Wv

Av'nw'-

'ﬂm“'ﬁ

)w

m

~$r:"-

Fink, M.D.
Professor of Psychiatry

Max

m»
‘

we.

�</text>
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                    <text>a a1:

v_}:-vw'-w‘-4vat‘vu

-_v.--,

MW

,‘

"wk.“

"JV-mart":

V

r,

"in:

_,,__

7,

”IJ'I—N

—,.._,.~'...._7,~~..

,.v—..—v....—,...l.

r—....-...._...-.—~..,—-..~r...»v.....v-~,....~.v-..

,

may“!

«u-

law

~I1‘W,

avg—mm}

an)”

Qctober

l7,

1967

Dr. Nathan 8. Eddy
7055 Wilson Lane
Bethesda, Maryland 20034
Dear Dr. Eddy:
Our pragram of qyclazocine and naloxone research has gone
well
during the summer. and Dr. Fink has Just notified me
very
2
the
grams cf heroin which you were kind enough to make
that
been used in the challengas and we are in need'
has
available

of

an

additional supply.

grateful if you would arrange to make available
to us an additional 2 grams cf crystalline heroin as soon as
practicable.
Thank you very much for your help.
I would be

Sincerely yours,
Alfred M. Freedman, M.D.
Professor of Psychiatry and
Chairman of the Department'
kn

cc:

Dr. Fink

�</text>
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                    <text>WW

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Hear Miss Samuels:
aA‘I-Fv'r'

(October in, l967

aertrude Samuels.

u,

“-

Your report on the methadone maintenance program is a commendable
one and will do much to cautious the support necessary for this research
endeavor. The enthusiasm of BrSs‘Dole and Nyswander for their program
is commendable, and your article reflects this very well.‘ Their greatest
contribution may yet he, not in the development of this program alone,

www.

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via-Himmmr’a-wu/w'm

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but in providing'atresearch climate‘for the development of other treat~
went methods of narcotic addicts. ,Up until a few years ago, controlled
studies of narcotic eddiCtion were limited by special regulations. The
change in climate, however, has lead to the evaluation of other agents
which might be useful in the treatment of addiction and Imong these are
the narcotic antagonists.

Two such compounds, cyclazocine, produced by Sterling~Winthrop
Laboratories and haloxone,'prodnced by Endo Laboratories. have re~
ceived very limited study. ‘But their initial evaluations demonstrate
these compounds to be safe, easy to use and potent in preventing re“
_

addiction. Like methadone,'however, they will probably be mast useful'
as "engagers" ~ agents that provide the basis for the re~education,
retraining and resocializetion‘of_addictss'
Among the problems in these studies is the high cost of the drhgs
involved. A cost that must be borne_by the pharmaceutical concerns
alone since public funds are not ordinarily available for such research
endeavors. Perhaps. in your later reviews_you will be able to report
on these methods as,ueil; encouraging both the public and scientist
to explore‘other“nays to treat the addicts ways that may have fewerlimitations than.the present methadone maintenance model.
—

Sincerely yours,
has Fink. ego.
.

Mf:ko

I

"

*

Professor of Psychiatry

�</text>
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                    <text>October 18. 1967
Dr. Danie? X. Freedman

Chairman, Department of Psychiatry

University of Chicago
Chicago,

Illinois

Dear Dan.

Itii

wiii be pieased to participate in the
symposium on psychomimetics at the forthcoming ACNP meeting.
Enclosed is an abstract which summarizes the data which we
would iike to present.
0r.

and I

Thank you very much

for your invitation.
Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                  <elementText elementTextId="102288">
                    <text>1‘11”»vﬁnv umfmwr'mv W

V,

”'1"

V

’

‘

..

,

‘

v

.

,

'

'

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’12:.

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_

_.Qgteber 20, 1967

:

y
7

‘

,

i

Dr. Albert J, Siiyeimah
Chairman, Senartment ofyPéychiatry‘l
The State UniverSity
.Rutgers
—

New'Brunswick, ﬂew Jersey
'

Bear Br. Siiverman;

behalf off9r§ Nafi7Kiremitci whom I have
recommenéed to Dr. Nennc_for the position 9f“Directer of Research
"
I?
at the Marlboro State HQSPitai.
I am-writing On

'

'

'

~

.

of Dr. Kirawitci’sawerk in.1960*61 when he was in
new York. After that he returned to Turkey te compiete his
military service and on one of mygvisits'te IStanbui I met him‘
and recommended his appointmant tb,tne MisSouri Institute'of
Psychiatry at the University of Eissouri School of‘ﬁedicin91
'He jéined the Institute in‘iQESfanﬂ has been an active particigant.
in the psychopharmacoiogicai:researCh programs. These studies.
were under the-direct supervision of Dr. Turan M. Iti].
I knew

‘

‘

The

principal studies with_which

he

haéibeeniiéentified

xhe
are those of phencyciidiqe,in chronic schizophrenics andintravenous
geffects can G and behaviar in voiﬂnteérs 6f the acute
'administratian of experimental psychoactive compounds., Iﬁ-these
studies his principal respansibiiity has aeen ciinicai supervision
and behavioral observations.f
,i
'

'

abiiity ta Carry through a project
of reportsthich'are now in press. He

Br. Kiremitci has shawn an

and has

written

a number

ability as a psychcpathpiogist and has demonstrated
interest in the usg cf rating‘scaies;

has

»

optimistic that

he

a special
V

.

is

capablé to carry out independent
in'
clinical research.projects.; Insofar as he is interested
him
recommend
estabiishing hisiown-study pragram; I am pleased to
for tha position described hy arxjﬁenno.*
I am

‘

,

My

best regards.
Sincereiy yaurs,

mum-swarmwumwz-wznwmmvw—Wrgmaw

‘

mezkp'

ﬂax Fink, M.0.

Prpfessor of Psychiatry

*

r,

,

r

mamrmnm~wzyrnﬂy

,‘

�</text>
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October 20, 1967
Mr. Robert Maxym
Swarmhmnre Cbllege

Swarthmore, Pannsylvania

Dear Bob,
Thank you far your letter. Of course we are pleased
have a.mamber of our staff visit with you and share his

to

experiences.

nu:

rm

Incidentally, sinca we are not paying him well, perhaps
the Cbllege could, in addition to defraying his expenses,

pmnwide a.modest honorarium.
Good ludk!

Sincerely yours,
n;

u
m

A-_-

n’

Fink, M.D.
Professor of Psychiatry

Max

marmrz-mw.‘

MF:kp
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”a, Y.“ I”;

.7

?_vnwmmwww‘mﬁmf*“w

v,v,‘..;‘,;7...,‘,.

1

umwwmwzm-p&lt;M-—v;m—mm—rp-q.

.

mum-“mm

~'

October 20 , 1967

Appletm, Director
Departuant of Clinical Chemistry
Metropolitan Hospital
Mr. Harold D.

1901

New

First Amue

York,

New

York 10029

Dear Mr. Appleton:
Thank you very umch for your assay 0f tha ample of heroin
sumitted to ya: recently. I am most pleased that the results
denonstmte that we have had an active preparation. This assay
will permit us to report
the results of our experiments.

mmly

Simmly

yams. ,

Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>w.

z-

~71anwvv1

L—pW

HH'A'W

,

m-v-u

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'

j

, ,

mum

.

.

V.

.

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-

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,

,

'm~

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\w’vmrnw "mvcm&lt;~'&gt;"v“’

w

vu'mu-m-rv

October 20 , 1967
Dr. Roy R. Grinker, Sr.
Chief Editor

Institute for Psychosomatic

and Psyohiatric Research
29th Street 8 Ellis Avenue
Chicago, Illinois 60616

Dear Dr. Grinker:
Hy associates and I are pleased to submit the enclosed
report ”Thioridazino and Chlordiazepoxide, Alone and Combined,
in the Treatment of Schizophrenic Patients" fOr your oonsidera~
tion for publication in the A.M.A. Anchiveé 05 Geneaat
Psychiatny.
This report is the first part of three describing the clinical,
EEG and then relation of EEG and clinical
effects in a carefully
controlled study.

Thank you,

in advance, for your cOnsidenation.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

enc .

�</text>
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                    <text>-WV

, .,,,__‘mr....w,..,u_,-,_m..

.W

“an”,

.

~

_

.

‘

.

1W7 Cmmings Drive

'Riomond, Virginia
Dear

Dr

«mu-«Wm.

w,

.,,i

,

_

_

1,577.,—

,

W

17

q,.._ww-.~wwmwm"Irv-'Iwmv‘ﬂhru'

..

,,

pleased to enclose a copy of the ” mist-2d protocol of
our study“beamate in NarcOtic Addiotion. In this study we
wish to take advantage of the antimony foams of this
nomaﬂdiotjng compound to study so aspects of importance
the treatment of nerootic addicts » its use as e mintenanoe
treatment of the addicts and in the treahsent Of withdrawal

I

am

in

.

symptoms.

.

Insidition,lsnemlosmaxemxoopyofamportby

Drs. Feldman Mines and Jackson. This report was presented
at the 1967 nee-ting of the American Psychiatric Association.
Dru. Feldman was kind enough to send this draft of his report
V

to us. It stimlated the present study
A previous draft of this protocol with e smilsr pmgran
been
has
approved by the appropriate committees of this college
and we would have no objection to filing the necessary dements
for this study ﬁith the FDA, should this hem necessary.
,

I

would be pleased

discuss this project.
‘Ihafﬂc.

you

to have

you

visit our laboratories to

for your cooperstion,
'Simerely yours,

zurwww

«(up

nwxyv-vrw-wn—w.w,.wvvw~mw..ww-ws~m.~\ r7“w'lrr'rvrlwv&lt;‘tan—

2-3, 1957-

.«vr

.

V

‘

Owens:

“.2...“

.,

,

,

Dr. Fletcher Owens
A. E. Robins Coupeny
vzrz

m

,

Max

Pinker).

Professor of Psychiatry
,

.

�</text>
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                    <text>"Tum—m, ml,’,ww‘yc«m&gt;r:zrm‘m
paw-“WW

.niwuwwrv.‘nr nm\

»-.

«am-pwqmu WW~W

»

w.‘ I—VII-"ﬁw.n-rvnmmn-w-wnw-m Amy-nvur“.1—...“qu

October 23 , 1967
Mr. Inward

J. Fitzgemld, Jr.

District Director of Intamal
120

New

01ml] Street

York,

Dear Mr.

New

Revenue

York

Fitzmld:

part of the research program of the Departmnt of
this college, we hm been undertaking studies
an Wtic addicts. We wish to extend these to include
As

Psychiatry of

studies of
be

marijm.

Would you

kindly send

me

the appmpriate forms which must

filed to maintain argobtain supplies of marijuana?

Im'

Sincerely yams ,
TWF'PYWVn‘ﬂw

an

-vmmrrmvmxuwv

"a"

a"

"saw-w.

«ca-urn",

may”

.mu

mm”:

--.y,»mwu—.v&lt;-.u w- Wm“ amnmr-w—

Max

Fink,

H.113.

meesaor of Psychiatry

W

&lt;Vw'vw-r

—~~

.

�</text>
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                    <text>‘l’?wh.,‘vi""n-r—mnm—.w»-www
ur—

.

H

,

V

'

A

7."

»

WW...“

“

,

away”:"g-v‘v;W¥W’W~~v-1II—mmwmﬂ

{WW—1;"

October 23, 1967

0. tar Haar
Sales Manager

Mr.

E

g

{

Elsevier Publishing'Company
P. 0. Box 211

%

é

g‘

i
E
,.

nvwhnNy-Wmmurg'w"Irvin-n"!

5mm",

Amsterdam, The Netherlands

I have just received tha September issue of Eioevieh

and am embarrassed by the

Pitagnub Ln 3min

description of the

Volume 28

Hawaii, "Anticinlhwergic Drugs."

The two paragraphs of description, written by myself,
appeared too pedantic and remarkably unclear. Attached is
a &amp;ammﬂwa:simpler version and perhapsrmay'meet a better

test of clarity.
I trust this is helpful.

Sincerely yours,

.0,“

“1.1.1”,

‘

Fink, M.D.
Professor of Psychiatry

Max
-

“*1“

"mwnv‘w

mm—mwmwm—v

,

of

Newé

v.2":u-‘W‘r‘r wwwar—w—v-w—vw-mww-

�</text>
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                    <text>October

21‘

, 1967

Dr. T. P. 8. Watts
Geigy Pharmaceuticals
Ardsley, New Yerk 10502.

Dear Paddy,

I

is a revision of the ketimiprmnine protocol. I
tried to include your suggestiana , QSpecially tinge regarding
on the use of the Hamiltm Rating Scale
diagnosis. We are
plus sane additiomldiagxmtic features to assist us in classifying.
our patiants in this study program As soon as this lama!!! is
running, I will send you a description.
have

Enclosed

Welcome back!

m
My

best regards.
Sincerely yours ,
Fink, M.D.
Professor of PSYChiatry

Max

611C.

�</text>
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                    <text>October

2%,

1967

Dr. Lino Covi

Assistant Professor of Psychiatry

he Joims Iiopkins University School of Medicine

601"Earth

Broadway

Baltismm, Maryland 21205
Dear Dr. Covi:

are vew' much interested in collaborating in studies
in your letter of October 20.
changes induced by diphenyb
there
systematic
are
Surely, if
become
manifoat
in this; population,
should
hydantoin, they
under placebo
recordings
there
systematic
especially if
are
We"

Such as the one you described

oomlitinns.

As you may know, them ie midwable ambiguity as to
the effects of diphenylhydantoin alone on the scalp recorded
EEG in populations other than nonspepileptics.

have established collaborative relationships with two
other hastitutions during the past few months and would be
pleaseci to mice sﬁnilar arrangements with you. May I suggest
that you come to New Yoﬁ: at your cmvenience and my associates
and I can describe our program, the equipment mat would be
most useful and the procedume which will make such a oollabom»
We

tion immally helpful.
Please

call me at

(212} 389-7900 any afternoon.

Sincerely yours ,
Fink, M.D.
Professor of Psydmiatry

Max

MRkp

�</text>
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              <elementText elementTextId="29922">
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              <elementText elementTextId="29923">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                  <elementText elementTextId="102280">
                    <text>,.

,7 w

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.

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ﬁnnw'wa-vw'v---w.v-vw-o;w
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-

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.

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{”3“

E-

E

E

w

'ww'l‘nvv

October

'

v-z-‘er-rv

v—rw—

”Wm-ﬂ

1967

Dr. Willian Tabor

Dear Dr. Tabor:

Enclosed

is the study protocol and statement of investigator

for the fenflxmanine study.
As

awn as

I

have received an

initml

Iwillbepleasedtostaxtthiaatudy.
I am also enclosing a
mung forms.
_

few samples

supply of fenflm‘mm’ne

of the self and investigator

Sinmly yams ,
Fink, M.D.
Professor of Psydxiatry

Max

:m-«v-mu-m—vmn»

"Wu-P

vgwtmv :mvuq'umn-wwrW-unwnmmarvm—v-v---:-v-

A. H. Robins Cmpany
1H0? munings Drive
Rick‘smnd, Virginia

mn-vvv

1—,",

2*},

-..w~.»v-x'-chn(

Mszp

w-w-I—v—w-w—rv-rv

.

�</text>
                  </elementText>
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        </elementSetContainer>
      </file>
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            <elementTextContainer>
              <elementText elementTextId="29912">
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          <element elementId="48">
            <name>Source</name>
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            <elementTextContainer>
              <elementText elementTextId="29913">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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            </elementTextContainer>
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            <name>Language</name>
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      <file fileId="1653">
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                <elementTextContainer>
                  <elementText elementTextId="102279">
                    <text>V

“arr—h. v" _.V

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~11

2-,“.m-m,¢,....payphwwmwwzwxrw. _ywm\vx—n,1.y.~uw

~-

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1...,

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nmm

‘October 24. 1967

Sr. Torah

H.1t11

M1ssour1 Institute of Psychiatry
5400 Arsenal Street
St. Lou1s, M1ssour1 63139
.

‘

Dear Turan,
EEG and
I have reco1ved the two reports. tr1f1uper1do1
Lthe psychotropic drugs os1ng quant1tat1ve EEG ana1ysis Both
'reports are good and I am_p1eased to have been a part1c1pant
—

You have been Verylbusy and-have created many new prints.
most of wh1ch I do not have. Boqu 11 be poss1b1e to ask Yu1men
to send me a s1ng1e pr1nt of each of the fo11ow1ng, and, perhaps
a 2 x 2 511de?
‘

‘

»

~

’

,

MIP

112a."

puma-x

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323
337]
328
338

L'u'

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EEG

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284‘ PHRS
285 Por1od Ana1ys1s
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WWI

Many

thanks and

successfu1.

«

I hope. that your

1n

was
.

'mew

A

stateréiy yours;
Fink; 1.4.0.
'Professor of Psych1atry
Max

Mszp

Paris

'

.

m-_ "w.

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                    <text>W wag-r-“

'vurwvnf. V“-[A'&gt; 'J~‘m~j,r-rw-: willy:~rw._.«)r';fl'k“i&gt;nlw

.Y,

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,

~«K-ﬁ “’-_-“V‘w-ow-rﬂ)-W-rW’mrw't‘iWW"'-\W'lrr-FIWFV'-7

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october 24s'l967
‘Dr. Alexander

Suite 6l7;

M.

Eon'

Africa House
Johannesburg, Seuth Africa
Pan

Dear Andy,

‘

$

I

_

_

have had a chance-to go over the.TTR data with HY~3263.
drug; and So," cannot make any cosnnent regarding

Iido not know this

-the.drng'infleance. It may be. that the central effects.were.
quite small,'and that this may be related to the failure to see
changes in language. As you know. our major difficulty is in
providing an independent measure at the changes in central chemistry.
In many of our studies, behavioral change can be induced without a
‘

nw-w

_

umw’vn'xn

(v‘

concomitant change in brain chemistry or in

w-vl'qv

-theless, your data-is interesting
continued these studies;

WW”

and

i

am

EEG

criteria.

hever~

encouraged that you have

Of course, we will be pleased to have you visit with us
the APA meetinQS'in Boston. I would prefer your visit to be
the.meetings since I anticipate being quite busy just before
are planning to put up a demonstration of our EEG ~ computer
‘

swam-“mm,-

after-

after
as

we

techniques.

There are few major centers that I wOuld suggest you visit
once you come to this country and_these are Nathan Kline at
Rocklend State Hespitel in Orengeburg, New York; Arthur Sugerman

at the

Jersey NeurovPsychiatric Institute in Skillman, New Jersey;
at Tulane University in New Orleans, Louisiana; and,
of course, the Missouri Institute of Psychiatry. Turan has continued
the psychopharmacology program.there and I am very pleased with the
'results which he has produced. I do not know of any majer center on
the West Cosst, other than that of Dr. Hollister in Pelo Alto, or
Sidney Cohen in Los Angeles. The first is interested in secondary
effects of new drugs end the secend in LSB.
New

Donald Gallant

.

.

-

'

With regard-to your study of Stelazine and.Triperidol. we are
able to translate the rating scales‘provided they have been dene
carefully and, if there are sufficient samples to provide us with a
measure of the average and variability for each patient prior to
drug treatment. In these analyses. we continued to use the model
of change from the ere—treatment behavioral scores. PleaSe tell
me what shape your date is.in and the number of ratings per patient
at different times of the treatment program.i

�Dr. Don

~2-

October 24, 1967

Our psychopharmacoiogicai studies continue to go well with
much emphasis 0n cyciazocine as an antidepressant and a new anti-

narcotic, ﬁaloxone, in the treatment of addicts. This group of
anti-narcotics is both interesting and rewarding.
I look forward

to having you

visit

with us.

Hy

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
.
w

w:—-,a-.~ru:ronwm~vrnnwv=-.—..

:-

:wvvi:

unrw'vvww‘wsw

Mszp

best regards.

�</text>
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                    <text>-

October 25. 1967

Dr. H1ll1am laborl
Rob1ns Company
l407 Cummings Dr1ve
; Richmond, V1r91n1a
A. H.

r113":

(Béar

&lt;._,.

7—“

Bill,

~

Enclosed are the completed study protocol pages and
supporting documents for the study of butaperaz1ne syrup.
as maintenance therapy 1n chron1c schizophrenic out-patients.
I am enclosing copfas of the _USPHS forms as we plan to use
these 1n th1s study.
,

Thls study has been approved by the appropriate committees
of the New Yerk Med1cal College and I hers only to awa1t the
usually a matter
approval of the Comm1ss1oner of Hosp1tals
of two to three weeks. The Study may be undertarken at that
time or as soon thereafter as we have rece1ved the butaperaz1ne
—

syrup.

W staff has made Some suggest1ons regard1ng the type
and 51ze of bottles that may be necessary far these patlents:
May I ask that you send us a small supply, enough for only a
few patlents,1n1t1ally. As soon as we have had some exper1once
1n del1ver1ng
l1qu1d med1cat1on to our patients. 1 wOuld than
_l1ke to be able to d1scuss w1th you the amount and form of a
more def1n1t1Ve supply of the Syrup.

1'

a

&gt;

‘

Thank you

has called

It

me

.

for your asS1stance w1th Tybamate. Dr. Fernandez
and I have alreadysent h1m a copy of the protocol.

was good

to have you vis1t us.
S1ncerely

Max

F1hk,

My

best regards.

yours,
M. O.

‘

9rofossor Of Psych1atry
MFEkp

�</text>
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