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,

ﬂarch 7, l968

Dr. T. Robitscher
Assistant Medical Director

Ayerst Laboratories

685 Third Avenue
New York. New York lOOl7
Dear Dr. Robitscher:

Since our discussions in Puerto Rico 1 have sought, in vain.
to set up a study of Sordinol which you described so well.
Unfortunately, the population available to me at a neighboring
state hospital does not lend itself to long tenm studies.

are interested in undertaking evaluations
in adult acute mentally ill and have available populations of
depressives as well as acute psychotics. If I there are other
studies of interest to Ayerst Laboratories, would be pleased
to have you call on me.
As I

My

mentioned.

we

best regards.

.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>March 7, l968

Dr. Lee E.

Hollister

Associate Chief of Staff
Veterans Administration Hospital
3801 Junipero Serra Blvd.
Palo Alto. California 94304
Dear Leo.

.

While I have more than a half dozen reports that are
waiting to be done, I am stimulated to accept your invitation
to write a summary of EEG and drugs for practicing physicians.
I would rather not give you a date because I am sure I cannot
meet it, but I am sure I will attend to this at the earliest
date I can.
My

best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>March

Dr. William

M. K.

7, l968

Zung

Assistant Professor of Psychiatry
Veterans Administrttion Hospital
Fulton Street and Erwin Road
Durham, North Carolina 27705

Bill,

Dear

I look forward

If

you come-in the evening
(516 466-5444).

home

and

to seeing you here

I

would

like

you to come

First Avenue), at 10:00

on Wednesday, March

before, please call

me

any.

He

will

to Metropolitan Hospital (97th
lSth floor, Mental Health Clinic.

make up

visit the laboratories
the rest of the agenda as we

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

my

am,

In the afternoon I would like you to

at l?2nd Street.
go a

at

l3.

�</text>
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                    <text>March

Dr. Joseph

Jaffe

The William.Alanson white
20 West 74th Street
New York, New York

7, 1968

Institute

Dear Joe,
I have

the g;§.M.D,

a

read your report on deniie personality in
I found it very interesting and would appreciate

just

reprint when this is evaiiabie.
Incidentally I hear that Ed Heinstein

to Mt. Sinai this summer.
My

may

be returning

best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>March

7. 1968

Miss Mary-Frances Thompson

Coordinator. Special Science Projects
American Institute of Biological Sciences

3900 Wisconsin Avenue. N.“.
Washington, D.C. 20016
Dear Miss Thompson:
Thank you very much

for your invitation to attend the

the average evoked potential.
would like to participate.
and
invitation
your
NASA

conference

on

I

accept

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>March

l2,

1968

Dr. waiter Modell, Editor
Clinical Pharmacology and Therapeutics

Professor of Pharmacology
Cornell University Medical College
l300 York

ﬂew

York.

New

York lOOZl

Dear Dr. Model]:
I am pleased to enclose an original and one xerox copy
of our report "Behavioral and EEG Studies of Naloxone in
Heroin Dependence" for your consideration for publication
in Ctinieaz Phanmacotogy and Theaapeuzica. while this report
describes our experiences with a small number of subjects,
we believe the data to be of sufficient interest and timeliness.
The studies cannot be extended because supplies of naloxone
are not available at present.

Thank you

for your consideration.
Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                  <elementText elementTextId="105572">
                    <text>MarCh

Hr. Joseph V. Moran

7

I4.

1968

,«

National Institute of Mental Health
5454 Wisconsin Avenue
Chevy Chase. Maryland 20203
Dear Mr. Moran
I am

Re:

MH—13358-02

and l3003-02

writing with regard to the restriction in international
March 6. l968.

travel in your letter of

For many years, we have participated in the meetings of
the GIMP - the principal international organization 9 devoted
to psychopharmacological research. The next meeting is
scheduled for April 24 - 27 in Tarragona.5pain. There are two
presentations by members of this staff on that program.
Funds

for this travel are available in ”ii-13358

and 13003.

like to send one representative of this program
both
to present
reports. Curtailment of all travel would
serious embarrass the organizers of this meeting and would
He

reflect

would

the integrdty of our commitments. We would be
grateful if permission could be granted for one participant
only instead of the two permitted for in these grants.
on

Thank you very much

for your understanding.
Sincerely yours.

Mathink,

M.D.

Professor of Psychiatry

Mszp

-

'

�</text>
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                    <text>March 26. l968

Dr. Joseph Seifter
Research Professor of Pharmacology
Dept. Coordinator of Sraduate Program
new York Medical College

New

York. New York l0029

Dear Dr.

Seifter:

I have reviewed

to April

ll.

your request for lectures from April l

It is difficult to undertake this mission at such short
notice since 1 will be away part of the time. The principal
other neuter of the Department able to carry out this series
is

Dr. Herman C. B. Oenber, who can be reached

State Hospital.

at

Manhattan

Enclosed is a list of the seminars now in progress in
the Department. Perhaps these lectures. especially those
presented by the invited speakers would be of interest to
the students. It is probable that these seminars will be
held again in l969 and perhaps the next class of students
can be scheduled to attend then at that time; or. we can
arrange a special series for the graduate students.

Sincerely yourS.
Fink, M.D.
Professor of Psychiatry

Hex

Nszp
bcc:

0r.

Freedman

�</text>
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                    <text>March

Dr.

Fletcher

A. H.

l8, l968

Owens

Robins Company

1407 Cummings Drive
Richmond 20, Virginia

Dear Dr. Owens:

recent conversation you indicated that the on-going
of
tybamate in the treatment of narcotic addiction, using
study
dosages up to l2 grams daily exceeded the recommendation on the
In our

pncﬁﬁge

'

insert.

As you know, we have already reported on an initial group
of patients with these dosages without problems. You indicated
that a revised IMO is being submitted to the FDA and that this
would be done within the next two weeks.

Insofar as it would raise problems of withdrawal and be
medically contraindicated, the present group of patients will
continue to be treated during these two weeks but we plan not
to add any new patients until the IND has been filed.
Thank you for your cooperation.
Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>mum-warr-

March

l8,

1968

Dr. Merle L. Gibson
Di rector

Acting

Division of Neuropharmacological
Office of ﬂew Drugs
Bureau of Medicine

Washington, 0.6. 20204
Dear Dr. Gibson:

RE:

IND

2640

When I left the University of Missouri in 1966. the
remaining supplies of CI-395 and the study program was turned
over to the director of the Section of Psychopharmacology. Dr.

Turan

M.

No

ltil.

studies of 61-395

May I

have been undertaken in

suggest that you write directly to

further information.

him

New

York

for

any

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                  <elementText elementTextId="102431">
                    <text>March 18. l968

Dr. Paul H. Slachly
Associate Professor
University of OregOn Medical School
3l81 S.H. Sam Jackson Park Road

Portland. Oregon 9720l
near Paul,
what

I would be
we

pleased to have you

are doing

at Gracie Square

visit

and

and could show you

at Metropolitan Hospital.

Because of the organization of our project, in which Dr. Kalinowsky
is the consultant, I would ask that you not contact Dr. Impastato

to

visit

our project because

To meet

the

this

may complicate

staff of the Narcotic

the relationships.

Addictihn Program.

it

to came during the week and if Wednesday
these would be ideal. If this is not‘
available
Friday
or
are
I
would
be
glad to meet you on Saturday morning, but
possible,
I cannot speak for the other members of the staff.

would be necessary

we
me when

could

visit

you know

»

Gracie Square on

your schedule.

either day. Please call

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>March 18, 1968

Mrs. Mary Ann Stallings
826 Avalon Road, Apt. 6
Lawrence, Kansas
Dear Mary Ann,

Just returned from Europe and was saddened to
find your note waiting for me at home. While I only knew
Paul Feldman professionally, I admired his work and was
I have

pleased

when you confirmed my

opinion.

I do not know if there is anyone capable to continue
work
and so this would be a loss not only to psychohis
pharmacology but to Kansas as well.

are continuing to grow. The clinical
out-patient are quite active. We now
facilities
EEG
have an
laboratory at the hospital and one for basic research
at the College. The computer unit is very busy. It has takenI
me two years to find myself in almost the same place as when
left Missouri. but I hope I can build a professional program
from this base.
Our own programs

both in and

you plan to visit New York in the near future? If so,
I would be pleased to have you visit with us. My best regards.
Do

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

Mfzkp

�</text>
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                    <text>March 19. l968

Dr. J. F. Remarque.
Elsevier Publishing

P.

O. Box

le

Vice President
Company

Amsterdam, The Netherlands
Dear Dr. Remerque,

believe a cooy of Antichotinengic ﬂange, Volume 28,
in Benin Reocanch, should be sent to each of the
senior authors. notably Drs. Hikler. white, Himwich, Votava
Herz, Vojtechovsky, Longo, Domino. Ilyutchenok, Euros
Carltoni
and
I

Paogeeao

t

.

For this reason I would be grateful if you would arrange
to send one to each of the senior contributors listed with a
note: ”With the compliments and thanks of the editors."

for

In addition, please send

15

copies.

Thank you very much

me

three

more copies and

for your coooeration.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

bill

me

�</text>
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                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                  <elementText elementTextId="102428">
                    <text>“’5

"wwwv,

&lt;

1w—vr.’~.v.w

-,—

-a—n—.-v.»

my,“

a-—-

“,.._.,.v.

"f-..

,

,
~.~.5--

March 18, l968

”-mmw.

Dr. Paul H. Blachly

Associate Professor
University of Oregon Medical School
.V

.

own—nun,

._.

mwﬂ‘1varcww-v

3181 S.H. Sam Jackson Park Road

Portland, Oregon 9720l
Dear Paul,

visit and could show you
and
Gracie
at MetrOpolitan Hospital.
Square
what we are doing at
Because of the organization of our project, in which Dr. Kalinowsky
is the consultant, I would ask that you not contact Dr. Impastato
to visit our project because this may complicate the relationships.
I would be

pleased to have you

it

To meet the staff of the Narcotic Addiction Program,
would be necessary to come during the week and if Wednesday
or Friday are available these would be ideal. If this is not
possible, I would be glad to meet you on Saturday morning, but
I cannot speak
We

could

for the other

visit

members

Gracie Square on

me when you know your

schedule.

of the

staff.

either day. Please call

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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.

March

.

._,...,._,~,..

vw-v;—-......,.—._

_.

Dr.

l9, l968

Philip Bradley

The Medical School

Binningham
Dear

l5,

England

Philip,
When I

received the complimentary copy of Antioho£ineag£c

Danes I was very pleased. I think the
one and I look forward to the reviews.

presentation is

a good

wrote to Dr. Remarque concerning complimentary
copies for the participants, I found that we had agreed that
complimentary copies would not be sent to the authors.I
regreted this decision and have authorized Dr. Remarque to
send one copy to each of the participants at $7.00 a copy.
When I

I

trust this is agreeable to

you.

My

best regards.

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>March 20, 1968

Dr. Nathan 8. Eddy
7055 Wilson Lane
Bethesda, Maryiand 20034
Dear Dr. Eddy:

Enclosed is a page inadvertently omitted from the paper
“Intravenous Heroin Chaiienges in Studies of Opiate Dependence“.
Houid you piease insert this before putting the report
in the Proceedings.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>March 21. l968

Dr. Joseph 6. Bird

Sterling-Hinthrop Research Institute
Rensselaer, New York
Dear Joe,

pleased to tell you that an abstract describing our
experiences with cyclazocine as an antidepressant has been
accepted by the American Therapeutic Society for presentation
at their Honolulu session on June 12 - l6. A copy of that
abstract is enclosed.
I am

-

to attend this meeting and present this
be
may
helpful to have Dr. Zaks or Dr. Simeon

I am planning

report. It
participate with

me

in the event

Is

it

My

best regards.

we

stimulate interest.

possible for Sterling-Hinthrop to consider sending
participant to this meeting?

an additional

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp
P.S.

May I

remind you to send me the names of the

last

few

patientS'treated with cyclazocine according to your records.

�</text>
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                    <text>March 21,

368

Dr. James R. Merkel

Associate Clinical Research Director
The Squibb
New

Institute

Brunswick.

New

Jersey 08903

Dear Dr. Merkel;

revised the records of patient R.M., age 35
as requested in your recent letter. The patient had received
fluphenazine decanoate on 8/22 and 8/29. On a visit on 9/5
the patient states that she felt nervous, complained of
numbness and pains in the leg. tension. dysarthria and a
fear of crossing the street. The symptoms interferred with
her ability to concentrate.
I have

notation that the patient was “absent minded" was a
derivative statement which does not clearly reflect the data
on the record.
The

Because of the

patient‘s complaints. fluphenazine

decanoate was discontinued although there was no evidence
of an organic mental syndrome.

Sincerely yours .
Fink. M.D.
Professor of Psychiatry

Max

.

MFtkp

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                    <text>March 21, 1968
Mr. David Shapiro

Gracie Square Hospital
420 East 76th Street
New

York,

New

York

Dear Br. Shapiro:
I have ordered some equipment and

to Gracie Square Hospital to

supplies to be shipped

attention.

I would be grateful
you would notify your mail and receiving rooms that these
are to be accepted even though they do not have purchase orders.
I would be grateful if these would be put in the laboratory room.

if

my

Sincerely yours.
Fink. M.D.
Professor of Psychiatry

Max

HF:kp

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                  <elementText elementTextId="102426">
                    <text>March 22, 1968
Dr. Roger Meyer

National Institute of Mental Health
Bethesda, Maryland
\

Dear Roger.

Hiss Spiro called today and I tried to answer her questions.
Enclosed is a final draft of “Behavioral and EEG Studies of
Naloxone in Heroin Dependence” as submitted to Clinical Phermacolggz‘
and Therapeutics.

While we have been

told that

ENDO

will

naloxone, the approximate date is opened.

once again produce

present oyclazocine study program is in its final year
further studies will continue in the event the New York State
Narcotic Commission is willing to provide financial support.
The

and

has been an interesting experiment and I trust that this
report is helpful in the forthcoming presentation to Congress.

It

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                  <elementText elementTextId="102425">
                    <text>north 26. 1968
Dr. Joseph Soiftor
Research Professor of Pharmacology
Dept. Coordinator of graduate Program
How York Medical College.
new York. "on York 10029
_

Door Dr.

Soiftor:

I have reviewed your request

to April

ll.

for lecturos

from April

l

.

It is difficult to undertake this mission at such short
notice since I will bo‘augy part of the time. The principal
other memter of the Department able to carry out this series
is-Dr. Herman c. 8. Dunbar. who can be reached at ﬂoohattan
-

Stoto Hospital.

Enclosed is o-list of the seminars now in progress in
(tho Department. .Porhaps those loctures, espociolly those

presented by the invitod speakers would be of interest to
the students. It is probable that those seminars will be
holo again in l969 and perhaps the noxt class of students
can be scheduled to ottond than at that time; or. we can
arrangt a special series for the graduate studonts.
Sincoraiy yours.
ﬂax Fink, M.D.
’Profossor of Psychiatry

ﬁfzkp

bet: 9r. Froeéaln

�</text>
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Dr.
New

Phillip Polatin

York

722 West

ﬂew

York,

State Psychiatric Institute
l68th Street
New

York

Polatin:

Dear Dr.

Thank you very much for thinking of me and sending me
the historic report of organic mental reactions during shock
therapy. This is a historic report, as it was one of first
which communicated the EEG changes seen in these treatments.

Strauss was my first teacher in EEG and I owe
present interest to the enthusiasm which he
showed during my learning period in l952—53.
Hans

much

of

my

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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March 28, l968

Dr. Daniel X. Freedman
Chairman, Department of Psychiatry

University of Chicago
950 East 59th Street

Illinois

Chicago,

60637

Dear Dan,
Sol Boldberg has written asking that I send you copies
of the enclosed reports which have recently been completed.
These have been sent to Dr. Wittenborn forinclusion in the
Proceedings of the ACNP, l967.

It

was a

My

best regards.

pleasure to participate in the hallucinogen
reports are published soon.

symposium and I hepe the

Sincerely yours.
Max

Fink,

M.D.

Prlfessor of Psychiatry

MF:kp

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                    <text>3m

wﬁ-uva-yuv

m'm’ﬂﬁ'

'a'
.7"

mm

.

"'m,wmnz

March 28, 1968

w

narr-ra-mrr-M

Dr. Solomon C. Goidberg

Chief, Clinical Studies Section

'
.1,

w”

.i,.

n

rpm“.

Psychopharmacoiogy Research Branch

National Institute of Mental Health
5454 Wisconsin Avenue
Chevy Chase, Maryland 20203

ﬁwV

(?
~..:

Dear So].

L‘“m

for the suggestigggof sending preprints of
the
reports to Drs. Meriis and Freedman. The preplints
have been revised and compieted this week. I have sent the
Thank you

ACNP

-.n

‘

copies as you requested.

5."me

Sincereiy yours,

4"“15

mew

r

Tun",

«cu-v

Fink, M.D.
Profossor of Psychiatry

Max

r-v

‘r'u‘

-.v.v~r-1wur

Mszp

..

-.
a",
a
a‘

WW‘WWW’Wr,‘

‘l”"—v“-T‘

rwv

H

Wu»:

�</text>
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                    <text>March 28, l968

J. Prange, Jr.
Department of Psychiatry
Dr. Arthur

University of North Carolina
School of Medicine
Chapel Hill, North Carolina
Dear Dr. Prange:

Thank you very much for your paper "Enhancement of Imipromine
Antidepressant Activity by Thyroid Hormone." I have read this
with interest and can find little that I can criticize. The data
is impressive.

It may be of some help, and personal interest, to read
copies of some of your other reports. notably Nos. 55.and 64.
If these are available, I would appreciate the opportunity to
read them before the meeting.
I look forward

to seeing you in Boston.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>March 28, l968

Dr. Solomon C. Goldberg

Chief. Clinical Studies Section

Psychopharmecology Research Branch
National Institute of Mental Health
5454 Wisconsin Avenue
Chevy Chase, Maryland 20203
Dear Sol.

the

fer the suggestion of sending preprints of
and Freedman. The preprints
revised and completed this week. I have sent the

Thank you

ACNP

have been

reports to Drs. Merlis

copies as you requested.

Sincerely yours,
Fink, ".0.
Professor of Psychiatry

Mex

MF:kp

.

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                    <text>&lt;.'-r“"-‘-v

«NWT—“WWW“

.

March 28, l968

Dr.

Phillip Polatin

York
722 West

New

ﬂew

York,

Dear Dr.

State Psychiatric Institute
l68th Street
New

York

Polatin:

for thinking of me and sending me
the historic report of organic mental reactions during shock
therapy. This is a historic report, as it was one of first
Thank you very much

which communicated the

EEG

changes seen in these treatments.

first

teacher in EEG and I one
of my present interest to the enthusiasm which he
showed during my learning period in 1952—53.
Hans

much

Strauss

was my

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>March 28, 1968

Dr. Sidney Merlis

Director of Research
Central Isllp State Hospital
Central Islip, New York ll722
Dear 51d,

received a letter from Sol Goldberg suggesting
that I send you the three preprints which are enclosed. These
reports have been recently sent to Dr. Hittenborne 1n the
summaries of the 1967 meetings of the ACNP.
I have

I hope

that

I quoted your

in the phanttstice report.
My

mescallne studies accurately

best regards.
Sincerely yours,
hex Fink, M.D.

Professor of Psychiatry
MFrkp

�</text>
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                    <text>Earn»

"so

-

.mv

.,

w

t

\

.mn. mvm

-'w-«v)~'

x

v\~«v.«.-

wﬂvnh-a

,m

---«

-

"Maw“-

‘—

.wvr

‘

,

~

,

March 28, l968

Dr.

Julian

E. Rosenthal

Metropolitan Hospital
l901

New

First

York,

Avenue
York l0029

New

Door Dr. Rosenthal:

In October I had spoken to the Chairman of the Department
and Utilization
regarding my inability to attend the Audit
member
of the Department
Committee and was assurred that another

would be appointed.

unable to attend these meetings and ask that you
no longer mark me as absent and remove my name from the
Cami ttee .
1 am

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

"an—-

wwé

“'4-

up

.
.

..

w“

"F"3*”“WW-Wwaw'r:r'ﬂwwwvwv

.

�</text>
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                    <text>Twwwwm

March 28, 1968
Dr. Zola P. Horovitz

Squibb

Institute for

Georges Road

New

Brunswick,

How

Medical Research

Jersey 08903

Dear Dr. Horovitz:
I very much enjoyed having lunch today with you and the
other members of the staff of Squibb. As I mentioned, I am
enclosing a copy of a report which I have just completed and

submitted for publication in the Proceedings of the
I think this reflects my present position.
I would

ACNP

appreciate receiving a copy of your report in

the l966 Proceedings.

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

Mszp

l967.

�</text>
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                    <text>35::

v.-

u",
m

vow-

:w
m

«nam-

Y.»nq7;'l«"M"

harch 28, 1968

.4
1'

-

/,.

xvr‘w‘

icw:'.4

men-mm:-

Dr. Michael C. Barry
Assistant Medical Director

'thite

Laboratories. Inc.
New Jersey 07033

Kenilworth,

Dear Dr. Barry:

visit to the Department of
of
Istanbul, where I met our
Psychiatry it the University
examined
some of'the patients receiving fluphenazine.
coworkers and
You may recall that we sent them a supply of fluphenazine concentrate.
A few weeks ago, in order to keep the study going, we sent a
small supply of higher concentrated tablets iron France. I
examined the records and saw 7 patients receiving high dose
fluphenazine.
I have

Just returned

from a

‘

‘

’

-

_

Three of the patients who had

failed to respond to standard

doses of phenothiazines have shown a dramatic improvement with
300 to 500 mg of fluphenazine daily. 0f the 7 patients, 5 had
received between 100 and 600 mg daily, up to l0 days. ~In one

patient

I saw

was ninimum
patient who

extrapyramidal'symptons but in the others. there

rigidity, obvious only on fine testing.
exhibited the most rigidity was part of

series, receiving

30 mg

daily.

I was most impressed

that the very high dose

The one
a low dose

was

safe (in

7 patients) and apparently useful.' Dr. Polvan-and his associates
are continuing, within the limits of the medication available.

this

may soon become available so that
Thank
you very much far your cooperation.
study can continue._
I

trust the concentrate

Sincerely yours.
Fink. M.0.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>March 28. 1968

Dr. Ra1ph Jacobsen
Associate Medicai Director

Laboratories
Stewart Avenue
Garden City, New York
Endo
1000

11533

Dear Dr. Jacobson:

It

was very kind of you to send me a copy of the report
I think the idea is a very good one and. when
we are in a position to extend the na1oxone studies. I would
very much 1ike to adopt this method. 00 you think that your
chemist wou1d be ab1e to add ribofiavine to na1oxone? I am
sure that we can obtain the f1oorescent lamp suggested and

by 0r. Jones.

;

L

my

in

my

technicians cou1d carry out tests periodica11y.
Again,

New"?

v

my

thanks.

wg‘w/lw.

Sincere1y yours,
‘rvu'w

Fink, M.D.
Professor of Psychiatry

Max
it
E
E

i
E

1’
E

:-

I
E;

s
E

is
F

E

l

MF:kp

�</text>
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                    <text>March 28, l968

Dr. Daniel x. Freedman
Chairman, Department of Psychiatry
University of Chicago
950 East 59th Street
Chicago. Illinois 60637
Dear Dan.
Sol Goldberg has written asking that I send you copies
of the enclosed reports which have recently been completed.
These have been sent to Dr. Nittenborne forinclusion in the

Proceedings of the

ACNP.

It

was a

My

best regards.

l967.

pleasure to participate in the hallucinogen
reports are published soon.

symposium and I hope the

Sincerely yours.
Max

Fink,

M.D.

Prlfessor of Psychiatry

Mszp

�</text>
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                    <text>”arch 28, 1958
Dr. Stephen A. Weinstein
Labouatory of Behavioral Physiology
Johns JOpkins University

Baltimore, Maryland 21205

Dear Dr. Heinstein:
have read your letter to Science, describing the
Communications in Behavioral Biology. This reporting
system is of interest to us and I would be grateful for
any information regarding participation which may be
I

available. Is this system in operation

now?

Thank you.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>March 28, 1968

Dr. Hilliam Zung

Veterans Administration Hospital
Durham, North

Dear

Carolina 27705

Bill,

pleased to have you visit us in New York and I have
Just spoken to Dr. Itil who told me of some of the excitement
at the meeting in Denver.
I was

set

us thinking about many
enjoyed your visit very much.
You

different problems,

and we

writing to ask you for two pieces of information.
interested in the predictors for convulsive therapy
and any suggestions you may wish to make regarding the use of
the depression scale, with the established beta weights.
Dr. Abrams will continue his study and this would be a useful
I am

I am

addition.

I have read the abstract of some of
and when these are available. especially
effects, I would be pleased to receive a
My

your reports in Denver
those relating to drug

preprint.

best regards.
Sincerely yours.
Fink, H.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>March 28, l968

Dr. Arthur

J. Prange. Jr.

Department of Psychiatry

University of North Carolina
School of Medicine
Chapel Hill, north Caroline
Dear Dr. Prange:

for your paper “Enhancement of Imipremine
by
Thyroid Hormone." I have read this
Antidepressant Activity
with interest and can find little that I can criticize. The date
Thank you very much

is impressive.

may be of some help, and personal interest, to read
some of your other reports. notably Nos. 55,and 64.
of
copies
If these are available, I would appreciate the opportunity to
read them before the meeting.

It

I look forward

to seeing you in Boston.
Sincerely yours,
ﬂax Fink, M.D.

Professor of Psychiatry

MF:kp

�</text>
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            <elementTextContainer>
              <elementText elementTextId="31522">
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                    <text>w.“

_,

we...

c
j."

.
,—

awn-.7

1.,

v:

March 28, 1968

Dr. Stephen A. Weinstein

Laboeatory of Behavioral Physiology
Johns Jopkins University

Baltimore, Maryland 21205
Dear Dr. Neinstein:

have read your letter to Science, describing theCommunications in Behavioral Biology. This reporting
system is of interest to us and I would be grateful for
any information regarding participation which may be
I

available. Is this system in operation

now?

Thank you.

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>'EIW,-v1'vv‘.wr&lt;r

A

March 28. l968

Dr. Arnold G. Blumberg
m.

.

mm.

47

1'9!

Department of Medicine

Hillside Hospital

P. 0. Box 39
Glen Oaks, New York

&lt;2

’IIW'Dzv-gyl‘

Dear Arnold,

to read of the death of your mother. It
years since I last spoke to her but I
few
remember from the
visits to your home during our early
days on Long Island. Please accept my sympathy.

I was saddened
has been many, many

the unusual opportunity to discuss the report
“Enhancement of Imipramine Antidepressant Activity by Thyroid
Hormone“ at the forthcoming meeting of the APA. I know that
you could do this much better than I, and am taking the
sent to me by Dr. Prange,
liberty of enclosing the pre-print few
minutes to read it and
have
would
a
in the hope that you
to cement.
I have

thyroid extract been used to
convulsive therapy?
Has

alter the resoonse to

Have you,

or anyone else, attempted to confirm Dr. Prange's

Thank you

for your help.

suggestion?

My

best regards.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>:w- nu-.:.—rqny;-ﬂ

December

l,

1967

Dr. Werner P. Koelle

Senior Scientist
The worcester Foundation for Experimental Biology
Shrewsbury, Massachusetts 0l545
Dear Werner,

citation in the article “Effect
Diethazine
on EEG and Behavior:
of Anticholinergic Agent,
Convulsive
of
Therapy" the year is
Significance for Theory
With reference to the

l958.

I look forward

to seeing you in Puerto Rico.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:kp

.

way,” -,

“g

�</text>
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                    <text>December 4, 1967
Box X8503

York Times

New
New

York, New York

Sir:

Dear

past year we have established a number of
research
clinical
programs focussed on understanding the
on brain function and behavior.
of
drug
treatment
impact
During the

Primary emphasis has been placed on patients in our Mental

health Clinic who are
psychotropic drugs.

now

receiving

a

variety of

new

parallel program, we are establishing an evaluation
of convulsive therapies utilizing some of the more advanced
quantitative techniques for estimating changes in brain
In a

function and behavior.

for
me

for

‘

;

In both these programs we are now considering
full time staff members.

If this opportunity interests you,

a copy

of your curriculum vitae

an appointment.

and

applications

wbuld you please send

call

my

office (369-7900)

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

Mszp

�</text>
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                    <text>December

ll,

l967

Marion d. Finkel, M.D.
l900 South Eads Street

Arlington, Virginia

22202

Dear Dr. Finkel:

Enclosed is the original and four xerox copies of an
abstract entitled 9Narcotic Antagonists in the Treatment of
Opiate Dependence." for your consideration for the Fifth Annual

ieeting of the American College of Clinical Pharmacology and

Chemotherapy.

-

All the authors of this report are from the Department
of Psychiatry, New York Medical College. Both Dr. Fink and
Freemnan are Professors of Psychiatry, Dr. Sharoff is Associate
Professor and Dr. Zaks is ReSident Psychiatrist.
All correspondence should be directed to

offices at
I

5

East lOan Street,

new

York,

New

me

at the Department

York l0029.

trust this abstract is of interest.
Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>0%
December

l3.

1967

Mrs. Eva Green
528

New

hehartin Street

Westminster, British Columbia

Canada
Dear

hrs. Green:

Enclosed is a preprint of a report which has recently
appeared in the QJAJLA. and which describes the present status

of cyclazocine treatment. In addition, I am taking the liberty
of enclosing a preprint of another report which describes the
general philosOphy of antagonists in the treatment of narcotic
somewhat more fully, although it is based on the same
addiction
ate.
Cyclazocine is an experimental compound and is not available
except in research centers. It is given both orally and parenterally.
The dosages are indicated in the report. At the present time
cyclazocine has not been approved by the Food and Drug Administra~
tion of the United States.

that responsible medical offices are interested
additional
uses of this compound please ask them
in exploring the
to write to me.
In the event

Sincerely yours,
Max

Fink, H.U.

Professor of Psychiatry

Mszp
cc:

Dr. Ernest Taves
12 Hubbard Park
Cambridge, Massachusetts 02l38

Dear Ernie,

for referring Mrs. Green to me. As you can tell
from the heading of this stationery, I left St. Louis in June l966
and have been most active in the study programsiin New York. I
have established a laboratory for EEG and human psychopharmacology.
Our interest is in the effects of psychotropic drugs on behavior
and the work with narcotic addicts is but one facet of the broad
Thank you

Spectrum of treatment of the mentally.

�</text>
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                    <text>"v

4;:

neon:

I

.l.‘

.L

~»

or

",7.

.
.,

"um",

December 13, l967
Dr. Michael C. Barry
Medical Director

Assistant

white Laboratories, Inc.
Kehilworth; New York 07033
Dear Dr. Barry:

I have arranged for the concentrated Permitil to be
tested in Istanbul by Dr. Necmettin Polvan. He has just
written to me that the form is agreeable. I would be
grateful if White Laboratories would supply us with a
similar concentrate of approximately lGDmg/cc. If we plan
to treat 40 patients for a 3 month period, I estimate that
we will need 360 grams.
I would

like to file the necessary

ask your help and advice as to
Thank you

how

FDA

forms and would

to go about this.

for your cooperation.
Sincerely yours,
'

Fink, M.ﬂ.
Professor of psychiatry

Max

.L

L

t
.

w.

,

MF:kp
..

«It»

.

F

an

on".

L.

_.

u...~..~I-I-o

L-

�</text>
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              <elementText elementTextId="31452">
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          <element elementId="48">
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                  <elementText elementTextId="102405">
                    <text>"Wm—wwurvmmw»

v

ww'—~'rw~w-wnv

.

,

.

ww-

'

,

December

l3.

1967

Dr. Alain Sanseigne
Squibb International
460 Park Avenue
New York, New York

Sear Alain,
I have been asked by the Separtment's Chariman to present
of our findings in our new drug studies to the full
department staff on Friday, February 2. I have decided to present
the Prolixin decanoate and enanthate material. I would be pleased
some

if

you would be a

discussant.

I am also preparing some lectures for the residents and as
this will take place on Friday from ll to 12, I should like to
ask you to participate with me that day at ll o'clock.
The
‘

i

My

staff conference is
best wishes for

from 12:15pm

a Happy

New

to 2:00

pm.

Year.

Sincerely yours,

E

Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>[1W

,,v”

“rum-W w vemwuwr...

”mm

was.-m..nw,.m—.m-...~1., MW” .., .e-ww.r.r,-.,mww...“we»-.~.«.-rv.--..~.c~~.vvmem-mwwm-vww-«avw WV-Vmw-aw—

December

L

{

:

;

i

?

‘=

Dr.

Ju’orein

New

York

Associ 'rofessor of
550
New

Dear

First

l3, l967

Neurology

University School of Medicine

York,

Avenue
New York lOOl6

Juli,

Thank you very much for the contour maps of EEG spectra.
Both Don and I found them quite interesting. In some ways,
they are similar to the reports presented from UCLA. However,
the possibility that relationships can be discerned in the bi—
spectra which are ., obvious in the usual spectral pictures
makes this tool
interesting one and we look forward to
the further deve .. ent of this program.
‘

sleep figure is probably the most
I hav~
having looked at many sleep figures,
. ed
important.*ver,
so little in this field that I do not know how to comp - end
the figure you present. Is it possible that in the future a
single drug effect may be represented? If one could look at
the effect of a common compound like a barbiturate or the
intravenous administration of chlorpromazine,
it
would communicate much more to people like mysel
thigfi&gt;think
The

deSpite

my

Good luck!

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

ﬂfﬂt

W’ WZWW

L"

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                    <text>December
Dr. Joseph 6. Bird

l3, l967

'
»

Sterling-Ninthrop Research Institute
Rensselaer. New York l2l44
.

Dear Joe,

After submitting the various preposals to the Research

Committee of the Medical College, I find

grantor's agreement

that

one form, a

not submitted. We would be grateful
if you, or another responsible officer of the Sterling»
Winthrop Research Institute would approve the agreement.
enclosed Ind return it to’mes
was

-

.

The
who have
minimum.

first

depression_study has an additional ten cases
received cyclazocine for a period of four weeks
I have asked Br. Simeon'ahd 8r, Zaks to summarize
the status of the patients as of mid-December-and we will
write a formal report during the first weeks of January.
With this group of patients we found that the dosage schedule
suggested in the proposed comparative study is a suitable one.
As

are
study.

made
Hy

soon as the supplies of oyélazocine and imipramine

available,

we

are prepared to undertake the comparative
‘

best regards.
-Sincerely yours,

-

Max

Fink;‘M.D.

Professor of Psychiatry

MF:kp

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                    <text>December
Dr. Joseph 6. Bird

l3, l967

'
»

Sterling-Ninthrop Research Institute
Rensselaer. New York l2l44
.

Dear Joe,

After submitting the various preposals to the Research

Committee of the Medical College, I find

grantor's agreement

that

one form, a

not submitted. We would be grateful
if you, or another responsible officer of the Sterling»
Winthrop Research Institute would approve the agreement.
enclosed Ind return it to’mes
was

-

.

The
who have
minimum.

first

depression_study has an additional ten cases
received cyclazocine for a period of four weeks
I have asked Br. Simeon'ahd 8r, Zaks to summarize
the status of the patients as of mid-December-and we will
write a formal report during the first weeks of January.
With this group of patients we found that the dosage schedule
suggested in the proposed comparative study is a suitable one.
As

are
study.

made
Hy

soon as the supplies of oyélazocine and imipramine

available,

we

are prepared to undertake the comparative
‘

best regards.
-Sincerely yours,

-

Max

Fink;‘M.D.

Professor of Psychiatry

MF:kp

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    <fileContainer>
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                    <text>1.“... ,

Mwmnv. “.— «mu-rp— a.-...y-uu

,

arm“

W'-7-(I' 'w

December 13, 1967

Br. Richard P. White

Associate Professor of Pharmacology
The University of Tennessee

Memphis. Tennessee 38103
Dear Dick,
These

last

few weeks have been overwhelming, as I

tried

to complete a number of reports for the ACNP Meetings. 1 do
not know if you plan to be there. but if you are, then this
letter will be redone. If not, perhaps it answers some of
the questions you recently posed.

In general the Program Committee of the Society of Biological
Psychiatry wishes the abstract to be short so that
can be
puslished. The abstract which you sent me is quite satisfactory
and I think you ought to send
in.

it

‘

it

I

m;

will call

you

later

in the week. as soon as this hectic

period is over. to discuss with you the status of our project.

u,

7"

fey
"who—1"».

v
.

best regards.
Sincerely yours,

r
...

WW1)

AnWﬂ

Fink, H.U.
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                  <elementText elementTextId="102401">
                    <text>December
Mr.

W.

H.

l3,

1967

Bold

Clinical Research Associates
Squibb Institute for Medical Research

Manager,

Brunswick,

New

New

Jersey 08903

Dear Hr. Bold:

It

pleasure having you and Mr. Gaglione visit with
as on Friday. As you requested, a copy of the summary statement prepared by my staff is enclosed.

that

The
we

was a

project is going well,

are planning to have a

to the full

at

12:15pm.

staff of the

present supplies
cooperation.
Our

and I

am

pleased to

tell

Department on Friday, February 2,
seem

adequate. Thank you br your
Sincerely yours,

Fink, M.B.
Professor of Psychiatry

Hex

HF:kp

you

presentation of this material

�</text>
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                  <elementText elementTextId="102400">
                    <text>Whv,'vr -u.,-- F'T‘f"-m&gt;

i‘l?ﬁn-‘k~ﬂo.'l'v“ﬂ"“‘w

‘

,

‘

.

m «m

-

'

\

,

.

1

,

528

haw

..

“*mmmmu"

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Ceiumbia
.

a

4
.

,

hrs, Green:'

Dear

'

,

.

-.

hehartin strut
Westminster. British

Canada

WV

.

i3, i?§7

'HVQecémber

Hrs.-Eva Graen

'v

ef'a raport which has recentiy
which éescribes the present status’
and
'appeared in the gggnhzg,
Enciosea

=

is

a

preprﬁht

.

of cyciazocine treatment. In addition, I am taking the iiberty
of enclosing a preprint of another,report which describes the
ganerai phi osophy bf antaQOhiSts in the treatment of narcotic
addiction somewhat more fully, titheugh it is baseﬁ on the same
data.
Cyclazhcine is an experimehtai compound and is not available
except in research canters. It is given both orally and parenteraiiy.
The dasages are indicateﬁ‘ih the report. At the present time
‘cyciazocine has nﬁt bash approved by the Food ané Drug hdministrao
tion of the United States.
In the event that-réspOnsibie medical Officés are interested
in expioring.the additional uses of this compnund please ask them
"
to write to ma.
-

'

'

»

‘

'

'

'

i

V

‘

.

Sincereiyybursi'
‘hax Fink,

h.a.

‘

Professor of Psychiatry

cg: tipDr. Ernest

Tang

12 Hubbard Parkr

~

‘

'

Cambridge, Hassachusdtts 02138

f
Dear Ernie,
_
Mrs.
Green to me. 'As you can tell
Thank you for referring
from the heading of_this stationery; I left St. Louis in June 1966
and hava been most active in the study programsiin New-York. I
,hava established a laboratory for EEG and human psychopharmacoiogy.
Our interest'is in the affects of psychotropic drugs 0n behavior
and the work with nardotic addicts is but one facet of the broad
&gt;

spectrum of treatment of the mentaiiy.

""""

"",.w

,_,

�</text>
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            <name>Source</name>
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              <elementText elementTextId="31383">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                  <elementText elementTextId="102399">
                    <text>December

l3. l967

Dr. Tito B. Dinzcy
Downey Veterans Administration Hospital

Denney, North Chicago,

Illinois

60064

Dear Dr. Dinzcy:
Thank you very much

for your letter.

I am indeed

interested

in the appointment of another internist to our Department. I am
enclosing a set of forms which will give me a better idea of your
background and experience. I would be grateful if you would complete
these and return them to me promptly.
Thank you

for your interest.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

HF:kp

enc.

�</text>
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                    <text>.‘u.

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».

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-&gt;

K’VW‘rVarrn-ﬂ‘

December 13, 1967
Dr. A. Arthur Sugerman

Chief, Investigative Psychiatry Section
c/o New Jersey Neuro~Psychiatric Institute

Box

1000

Princteon,

New

Jersey 08540

Bear Arthur.
Both Don and I have January 12

Princeton.
I

look forward to seeing you

set aside for

at the

a

visit to

ACHP.

Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max

�</text>
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                    <text>December
Dr. Marion

l9,

1967

J. Finkel

Director. Divisiontbf Metabolism

and Edocrine Drugs
Bureau of Medicine
Food and Drug Administration
Washington. D.C. 20204
um

,~

Dear Dr. Finkel:

mfg—wm-wwmrr

for your letter of December 13, 1967.
pleased to accept your invitation to participate in the
Fireside Conferences on May 3, in Atlantic City.
I am

m:.,mvm—nru

Thank you very much

I look forward
.

to seeing you.
Sincerely yours,
Fink, M.D._
Professor of Psychiatry

Max

HF:kp

�</text>
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                  <elementText elementTextId="102396">
                    <text>H. «my

a.

..\

.

,,

.

.-

.

..‘_4.p_vn,‘.u.»‘—_

om- 1177.15. ,Y-.. n.

v

“Vammna...;‘_ivs-,.s—v~~x,‘.\_,

“Thumb“, ”r

V.,._1,,..,

.

.

December

air. Si lverman

York State Bureau of
270 Hedison Avenue
New York, new York
New

.

,

,.

1

»

«wuwwq

”.3, “1 "w, (Wyn-:3»

”a”! a “my--

rajhmj-J‘”

w.rp.——WW.—V1W 1'11—

l9, l967

narcotic Control

Dear Mr. Silverman:

received a letter from George M. Balk, District
Supervisor of the Bureau of Narcotics, Treasury Department,
with reference to an application for registration under the
Marijuana Tax Act. In his letter, Mr.'8elk indicates that
prior to approval of this application for registration in
Class 5. we must comply with the New York State Law concerning
research utilizing marijuana.
I have

A

copy of our

original request to the

narcotics is enclosed.

Commissioner of

indicate the steps necessary to
State Law?

would you please

with the

New

York

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

Nszp

comply

�</text>
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                    <text>H. «my

a.

..\

.

,,

.

.-

.

..‘_4.p_vn,‘.u.»‘—_

om- 1177.15. ,Y-.. n.

v

“Vammna...;‘_ivs-,.s—v~~x,‘.\_,

“Thumb“, ”r

V.,._1,,..,

.

.

December

air. Si lverman

York State Bureau of
270 Hedison Avenue
New York, new York
New

.

,

,.

1

»

«wuwwq

”.3, “1 "w, (Wyn-:3»

”a”! a “my--

rajhmj-J‘”

w.rp.——WW.—V1W 1'11—

l9, l967

narcotic Control

Dear Mr. Silverman:

received a letter from George M. Balk, District
Supervisor of the Bureau of Narcotics, Treasury Department,
with reference to an application for registration under the
Marijuana Tax Act. In his letter, Mr.'8elk indicates that
prior to approval of this application for registration in
Class 5. we must comply with the New York State Law concerning
research utilizing marijuana.
I have

A

copy of our

original request to the

narcotics is enclosed.

Commissioner of

indicate the steps necessary to
State Law?

would you please

with the

New

York

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

Nszp

comply

�</text>
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                    <text>December

l9, l967

Dr. William R. Tabor
Robins Company

A. H.

1407 Cummings Drive

Richmond, Virginia 23220
Dear

Bill,

Thank you for the forms and the protocol for our demonstra~
tion with medical students at the new York Medical College. I

have signed the forms in the appropriate places and believe I
have answered all the open questions.
The

for

pharmacist here will prepare the amobarbital.

Thank you once again
a Happy New Year.

for your cooperation,

and

my

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

,

best wishes

�</text>
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                    <text>Gecember

l9,

1967

Dr. Henry Brill
Vice Chairman
New

York

State Narcotic Addiction

Control Commission

1855 Broadway

New

York, ﬂew York l0023

Dear Henry.
I was

pleased to have you

visit the

Department yesterday

for your patience in listening to our
experiences with naloxone. Enclosed is a copy of the letter
which I recently received regarding the laboratory tests.
and want to thank you

Your assistance in making this interesting compound
available for further study will be appreciated.
'

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                  <elementText elementTextId="105562">
                    <text>December 19, l967
Dr. A.

Cerletti

Eiological and Research Division
Sandoz Ltd.

Basle, Switzerland
Dear Dr.

Cerletti:

Enclosed is an abstract for your consideration for the
forthcoming meeting of the GIMP in Spain. This abstract
reflects recent studies in our Department testing a variety
of theoretical models in the treatment of narcotic addiction.
The report is related to the sessions describing the pharmacological
and clinical criteria of drug selection.
Thank you

for your consideration.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

Mszp

�</text>
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                    <text>v-w

w;

wean-m-umwm

wwa—vr'w

w-

”my

'W'Yiﬂmw-i

.....

,

December 19. 1967
Dr. Antoine Remand
47 Blvd. de L'Hooital

Paris 13, France
Dear Dr. Remand:

I have Just received and read the October l967 issue of
I find this newsletter of great interest and would
Igggg.
encourage you to continue making this newsletter available

to the

My

EEG

membership.

best wishes for

a Healthy and Happy

New

Year.

Sincerely yours.
Fink, M.O.
Professor of Psychiatry

Max

Mszp

�</text>
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                  <elementText elementTextId="102391">
                    <text>—.

v1

'w'..‘~"vvr\\.uvi

n '.\,«.~"\v.-

,~

n -.--..v~.-w~~,~.;$

;~.v.m~-.rv~.~

K"

a

,

—

nr.rv' nr'owvn

saw wum—x-wum—csr

.w-w

.v.

.v

.7,

mu“

.m

_..‘-.

V..-

_,.7nu

December 20, 1967
Dr. Joseph 6. Bird

Sterling-Winthrop Research Institute
Rensselaer. New York 12144
Dear Joe.
on

The meetings in Puerto Rico were
cyclazocine was well received.

excellent

and the

report

Dr. Cole did discuss his problems with me one I recognized
the difficulties he faces in trying to develop a new program.
I have read
My

the

new

protocol and

best wishes for the

New

it

is satisfactory.

Year.

Sincerely yours.
Max

Fink,

M.D.

Professor of Psychiatry

Hszp

�</text>
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                    <text>..

“n.7,,

,_

,
,v

.7...”

”w

.
J...

WWMWM,

q...

.

«ﬁn.

December 20. l967
rum-v—w—rﬁm'.

Dr. William Karliner-

Franklin Rodd
Scarsdale, New York
20

s’vryvp...—

www.my—m—V

:

..

.x-

AFTIW

'.'V‘-—U~ww-VII"

Bill,

Dear

Miss Harriet Bernstein, age 39, was seen at Gracie Square
Hospital on December 9 and in our EEG laboratory on December l9.
At Gracie Square she presented a mild organic mental syndrome,
moderate to severe depressive state and evidence of barbiturate
intake. She was mildly ataxic, labile and her Speech was slurred.

5-1

min—va-"mw‘

when seen on December l9, she was no longer ataxic nor did
she have nystagmus. The mental syndrome had been relieved and
she appeared anxious. tense and depressed. She had a pressure
of speech.
The electroencephalogram (#039) was symmetric without evidence
of a focus. The rhythms were highly irregular with mixed theta,
alpha and a moderate degree of high voltage beta activity. The
beta activity did not appear in-spindles or runs. The frequency
of theta activity was 5-6 cycles per second, with amplitudes between
40 and 80 microvolts. The record was filled with eye blinks
artefacts despite manual control.

hyperventilation was repeated three times and on the first
she exhibited a two Second burst of 200~250-microvolts.

trials

two

activity. with spikes.

These were symmetric and occurred
In the succeeding twenty
seconds there were random S~6 cps higher voltage (100 uv) runs.

.5

cps

after

80 seconds of

hyperventilation.

This record gives evidence of continuous, generalized cerebral

dysfunction.

The

presence of spike and

is consistent with cerebral dysrhythmia.

wave

bursts

on

hyperventilation

Recommendation: In view of the history, we cannot exclude
the possibility that the dysrhthmia is related to previous convulsive
treatment, although the probability is Very small. With this in
.mind I would suggest that she be continued on Oilantin treatment
and that the depressive state he treated with imipramine. If imipramine
is given rapidly in the hospital setting, we will know if dysrhythmia
is enhanced.,if the EEG is repeated when she is stabilized at your
.

average imipramine dose.
Thank you for the opportunity.25chee/7i7ﬂxoSee7ﬂdrV’
'

SinCerely yours,

Fink, M.D.
Professor of Psychiatry

Max
.

Mszp

.

�</text>
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‘

'4'”mwm'yvr,~&lt;—rmv&lt;-wc'

arm-w

December 20, 1967
Dr.

Julian J.

Lasky

Executive Secretary
Clinical Projects Research Review Committee
National Institute of Mental Health
5454 Wisconsin Avenue
Chevy Chase, Maryland 20203
Dear Jack,

writing with regard to our application for
“Theoretical, Clinical Studies of Convulsive Therapy.“
I am

(MH-lSSGl—Ol).

Since a number of the reprints are no longer available
file copies, I have arranged for xerox copies to
be made. Enclosed are five units which include representative

except for

reports related to
My

my

studies of the convulsive therapy process.

best wishes for

a Happy New Year.

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

Mszp
P.S.

I am also enclosing a reprint of a report
who is working with me on this project.

of Dr. Abrams.

�</text>
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“W'N‘Jmiwmmﬁnm-wurawn-r-

.mw-

\ ,.

- ”r."

w,”

v.04...“

.—

-nm‘;m&lt;mm—..

A

December 28, l967
Dr. Charles E. Marshall

Associate Director of

Clinical Research

ninthrop Laboratories

90 Park Avenue
New York, New York l00l6
Dear Dr. Marshall:

Enclosed is a draft copy of a proposed study of oxypertine.
\After reviewing the available literature and discussing the
clinical data with Dr. Hollister, my associates and I would
like to recommend an EEG study. It is our belief, that such
a study will provide data not otherwise available, which may
be most useful in identifying the target populations for this
psychoactive compound.
The

new York Medical Colleoe will be
lose. I
undertake such a study about harch

facilities at the

l,
available to
of
the
University
associates
at
of
my
have
the
assurance
also
when
Missouri who are willing to carry out parallel studies,
they are necessary.

In addition, we would like to consider a clinical study
the
in
population of the Mental Health Clinic, as soon as we
have detennined the EEG profile and made some recommendations
based upon that experience. In that study, we would like to
carry out a procedure similar to that followed in the clinical
evaluation of cyclazocine as an antidepressant.
I would be grateful for your comments. In the interim,
please accept my best wishes for a Prosperous and Happy hen
Year.

Sincerely yours,
Fink, M.0.
Professor of Psychiatry

Max

HF:kp

�</text>
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                    <text>.uu-u.—...umnn

y.‘r n

w

'7’,“ mm

5.-mm awn-i'h-vn- mny

.

-

,

.

,

-v.w. '- .7

.

mummy-:11v-wvw

M

rv-w—wwr-w-

a. r’uwm'vvir'vm‘nnwhurnﬁmﬁ- r—m-u
.‘

m; ~ w

-

v-vn-n-w‘w-

December 28. l967

8r. Chris J.

D.

Simpson Memorial

Zarafonetis

Institute

University of Michigan

Ann

Arbor, Michigan 43l04

Dear 3r. Zarafonetis:

Enclosed is an abstract ”Clinical Antidepressant Activity
of the narcotic Antagonist, chlazocine" for your consideration
for the forthcoming meetings of the American Therapeutic Society.
If this presentation is accepted, I will plan to present our

observations.
He

would

prefer presenting this data at the

or the first day in San Francisco since
at the Society of Eiological Psychiatry
Thank you

Honolulu Session,

I have another connittment
on June 14, in Washington,

for your consideration.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp
EDC.

0.6.

’K’M‘n-w

v-w—u

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”‘wm—y--.w‘..

m~.——~.

"‘-'.Im"fmwl—rm.

December 28, l967
Dr. Werner P. Koella

Senior Scientist

for Experimental Biology
Shrewsbury, Massachusetts Ol545
The Worcester Foundation

Dear Werner,

Enclosed are two abstracts for your consideration for the
forthcoming meeting for the Society of Biological Psychiatry.

report entitled “EEG Patterns Associated with Minimal
Alterations in the State of Consciousness" represents a detailed
quantitative assessment of the changes in scalp recorded EEG
The

in human subjects receiving minimal doses.of sedative and
stimulant drugs. The ability to differentiate the minimal changes
associated with these drugs suggests, that despite the general
misconception, sufficient data does pierce the scalp in man to
be of value in identifying small changes in consciousness as a
result of drugs.
are also submitting a second abstract, entitled “EEG and
Behavioral Relations of Phantastica in Man” for your consideration.
So much of the present interest in sleep and dreams is related to
the identification of the dream state with hallucinations in man.
The analysis of the EEG and behavioral changes with a
variety of
hallucinogens and our recent classification of this subgroup of
We

‘

psychoactive compounds
theme of the meeting.
May I

productive
My

may

contribute materially to the central

take this opportunity to wish you

New

Year.

a most happy and

best personal regards.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

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                    <text>.

.wmwnvmvw

5.1-.-

‘

4,

I, 3,” ‘ 110'?” ., u.” ”Lyman",

thrﬂmmg

.grn-u..r,.r.‘..., W 1. "a“... 7..“ Hymn—mu

W.v.‘gmn

L-w-r;r'n:waw,-‘~yh.w

ww-

,

.

,

_

wu.‘

v

"Hunt-IT;

December 28. l967
Dr. Jerome Levine
Psychophanmacology Research Branch

NIHH

Bethesda, Maryland
Dear

Jerry,
I

very much enjoyed our discussion of our

in San Juan.

common

problems

On my return to New York, I received a letter from the
Bureau of Narcotics suggesting that the marijuana license which
I requested would be forthcoming, just as soon as I complied

with the regulations of

New

York

State.

The

letter indicated

had to obtain approval by State authorities for such
that
research. Being a good citizen, I have complied with this re—
quest and have written for information regarding the necessary
procedure to be followed.
I now

recently completed a chapter for a volume on the
treatment of narcotic addiction and I am taking the liberty of
enclosing this report for your information.
He

have

Hay I

Healthy

take this opportunity to wish you

New

Year.

1'

_‘_.

gun“;

..

A
'

-wm~

a most Manny and

—-vv,—,.n,v:,-

Sincerely yours,

'Y-rv‘:7—,-z

'vu

‘5.
1:"
ZWM’F-‘W

Fink, M.D.
Professor of Psychiatry

Max
«.wn‘raﬂ'v‘

..

«1—,

MFtkp

«v:-

.,~—.wr

.

Way-1,...

mﬂf'r‘)

:wqunvw;

2W'vr'II—Il

~Mqr

-u

EHC.

-.{,_f-.:

�</text>
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                    <text>«nu-v

n-m.

q ~—

w: «a “WW“

,V

,,.,.. -

.ﬁ-«V

my“ 7“"..- n~._w.w...,.p.

Ivrnw'lwn‘nnv‘ 'y-wmu

December 28, l967
Dr. Roger Meyer

National Institute of Mental Health
Bethesda, Maryland
Dear Roger,

It

of you to visitzny laboratory and I was
have
the
to
pleased
opportunity to discuss our research
was kind

programs.

In the interim, until the naloxone paper is completed.
taking the opportunity to send you a draft of a chapter
in a forthcoming volume on the treatment of narcotic addiction.
This chapter reviews our present position with regard to
narcotic antagonists in the treatment of opiate dependent.
I am

my

best wishes for

a Happy and Active New Year.

Sincerely yours,
Max

Fink. ﬂ.D.

Professor of Psychiatry

Hszp

�</text>
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                    <text>Earn

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Dr. Herman C. B. Denber

3”,,

Director of Psychiatric Research

Manhattan State Hospital
Ward's Island

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New

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York,

New

York 10035

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Dear Hy,

Enclosed is an abstract for the forthcoming meeting of
the Psychiatric Research Society (GWON) to be held on March 22.
Following your recommendation of papers describing clinical
and basic science correlation, I am pleased to recommend the
report "Heroin - Challenges in the Evaluation of the Treatment
of Opiate Dependence.”

'ﬂﬁlwrimrwe.‘r'-vwv-'.I-»«a—v.,,.”..

Incidentally, Jonathan
on February l0.

IWWW'KW‘I'.‘IMJ~W-'w&gt;m”wmrwv,”

,

Switzerland
joining us?
My

Mum-v

r

best wishes for the

and I are looking to leaving for
Would you and Michel consider
New

Year.

Sincerely yours,

waiver—Mum.”

Irv—n

'

Fink, 24.0.
Professor of Psychiatry

Max

Vim-w.

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December 28, l967
Dr. Solomon Snyder
Department of Pharmacology
Johns Hopkins Medical School
725 N. Wolfe Street
Baltimore. Maryland 2l205
Dear Dr. Snyder:

presentation at the recent
As
soon
of
the
as your report is available,
Acnp.
meetings
I would appreciate receiving a copy.
I very much enjoyed your

Enclosed are our reprints which you requested, describing

our experiences with anticholinergic hallucinogens.
Thank you

for your interest.
Sincerely yours,

&lt;

Mun-w;

Fink, M.D.
Professor of Psychiatry

Max

“W‘vvmmmn

m-

m1wu&gt;w7w"'u

mmw‘cxmmw

1.
7.
r.

737,3

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Mszp
ENC.

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                    <text>December 29, l967
Br. J. Roubicek
Psychiatric Research Institute

Prague, Czechoslovakia
Dear Dr. Roubicek:
"r
v
V

r.

vw

_r,,-..,-:—ny.w.o

last visit to our laboratories, we discussed the
of
possibility your participation in the study programs of this
During your

department during l968.

to be in Europe in February and would like to arrange
week of the month.
I would like to arrive on Sunday evening, February 25 and visit
with you on Monday, February 26. This is a tentative date, for
I may be detained by one or two days, but I should know this late
in January.
a

I plan

visit to your laboratories during the last

it

would
be possible to visit with you at
have the opportunity to meet with your
Dr. Matousek in particular.

like to

New

In the meanwhile.

Year:

my

best wishes for

that time?
associates,

Fink, M.D.
Professor of Psychiatry

c

run-"1

v:
v.5

Mszp

and

a Prosperous and Happy

Sincerely yours,
Max

I would

�</text>
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                    <text>December 29, l967
Mr. Peter M. Irwin
315 w. 70th Street, #GJ
New York, New York l0023

Dear Hr. Irwin:
I am pleased to indicate that the erartment of Psychiatry
will extend an appointment as research assistant, effective
January l5, l968. In this program you will be responsible for
your assignments to me. The principal program in which you will
be working is in the evaluation of the treatment of narcotic
addicts, a program supported both by the USPHS and the New York
State Narcotic Commission. You will be asked to work 40 hours
per week and to assist in the data collection and data analysis
of this progrmn.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                    <text>December 29, l967
Dr. Turan

M.

Itil

Missouri Institute of Psychiatry
5400 Arsenal Street
St. Louis, Missouri 63l39
Dear Turan,

Enclosed are a few abstracts which have been submitted.
For the Society of Biological'Fsychiatry, I took your
suggestion and have sent the fenfluramine amobarbital data.
In addition I thought they would be interested in the phantastica
classification as well.
—

it

would be
I have never been to Honolulu and thought
a good Opportunity to visit there oy attending the American
Therapeutic Society. I have asked Jovan to begin writing
up a report of the cyclozocine depression data and this should

be done within the next month. It
would like to present in Honolulu.

is this material that

I

Some time ago I was asked to look at a compound,
oxypertine, because this will be a good test of the EEG
programs. I would like to do this in volunteers, however.
it may be helpful to me if you would be willing to run a few
of your patients and perhaps to do so with pentothal activation.
Enclosed is a proposed protocol. Please review this and let
A

me

have your comments.
My

best regards.

.

‘Sincerely yours.

Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                    <text>_‘m.,.:,,..‘.. .u, u...,.

.- ,

.

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, .
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~

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-

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December-29, 1967
Dr. Joseph G. Bird

Ster1ing~winthrop Research
Rensse1aer, New York 12144

Institute

Dear Joe,
As I have written, we
are now comp1eting the co11ection
6f data in the Open cyc1azocine study.
However, there are a
number of patients who wi11 continue on cyc1azocine
the
next two months and I need a sma11 additiona1 supp1y during
of

cyc1azocine p1acebo and active. Wou1d you be kind enough
to send us 1,000 - 0.25 mg cyc1azocine p1acebo.and an equa1
amount of active cyc1azocine?
My

best regards.
Sincere1y yours,‘
Max

Fink,

M.D.

Professor of Psychiatry

Mszp

“Ange“.

~,.w

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y':--

v

«a

‘

�</text>
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- v.7“ (rm-um

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«W

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December 29. l967
Dr. S. Clyde Strickland

ﬁerck Sharp and ﬁohme
west Point, Pennsylvania l9486
Bear Clyde.
As I described to you, we are in the midst of the evaluation
of the long acting fluphenazine, fluphenazine decanoate and enanthate.
It is necessary to give the patients an antiparkinson drug concurrently.
he have been in the habit of using procyclidine.

Recently. one of my associates felt that Cogentin might be
useful and we have made such a trial with some success. I
would like to extend this and I am writing to ask if you would
make available to us a trial supply of 2,000 tablets, 2 mg each?
more

A

copy of the protocol under which

is enclosed for your information.
Many

thanks.

My

this study is carried out

best wishes for the

new Year!

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

ﬁszp
cc:

Mr.

Tolkoff

2 ¢

,v

u .,- m.

.,,.

.‘

gym

�</text>
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                    <text>December 29, l967
Dr. M. P. Colvin
Medical Department
Burroughs Hellcome and Co., Inc.
l Scarsdale Road
Tuckahoe, New York 10707
Dear Dr. Colvin:

are continuing our study programs with long acting
fluphenazine and have found Kemadrin to be a useful agent.
Would it be possible for you to provide us with an additional
supply of Kemadrin, 5 mg tablets. either in a bulk of 5,000
tablets or in individual canisters of 20 tablets each, as
you previously supplied?
we

My

new.

Aw"

.&lt;

New

Year!

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
A.

”w.”

best wishes for the

Mszp

�</text>
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                    <text>December 29, 1967
Dr. Hilos Vojtechovsky
Institute of Pharmacology
Medical Faculty of Hygiene

Charles University
Praha l0 - Vinohrady, Srobarova 50
Czechoslovakia
-

.

Dear Milos,
You

have been so kind and thoughtful in sending us the

many wonderful new stamps of Czechoslovakia.
you and on this yearaend occasion. I want to
New

was kind

take this

opportunity to wish you and your family a most
Prosperous

It

Year!

of

Happy and

I am also writing because I plan to be in Europe in
February. I would like to have an opportunity to visit
Prague. Hy plans make the last week in February available
for a visit. as I will be on route to Istanbul.

In the same post, I am writing Professor Roubicek,
suggesting that I visit his laboratory on February 26.
Would it be possible to visit with you on February 27?
Perhaps you may call him and arrange a_visit that would be
convenient for both of you.
Again,

my

best wishes for the

New

Year.

Sincerely yours,
ﬂax Fink,

”.0.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>December 29, 1967
Dr. Norman E. Pitts
Chas. Pfizer &amp; Co.

Groton. Connecticut 06430

Pitts:

Dear Dr.
We

are in need of additional placebo Doxepin capsules.
kindly arrange to send us ten bottles, lOO capsules

Would you

per bottle.

Thank you.

Sincerely yours,
Fink, P'1oDo
Professor of Psychiatry

MéX

HF:kp

�</text>
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                    <text>“WNW

errr mm. y-mu»..mn-r~

ammunmmw-mrv-nm-v‘v.m4”

wry-Tww'WI-i-ww..uitmﬁw‘w

'm’w—a

:m

.

.

.

ﬁrm."I-

December 29, l967

Br. Necmettin Polvan

Abuulhak Hamid Cad. 76/4 Serin Apt.

lalimhane, Istanbul

Turkey

near Gr. Polvan;
Your recent letter about the fluphenazine and butaperazine
studies was most welcome. Turan has told me of the data from the
butaperazine study and I look forward to reviewing this with him
on my next visit to St. Louis.

pleased that the concentrated flunhenazine arrived and
found
useful. This supply was specially prepared for
that you
have
we
and
usﬁ
requested a large clinical supply be made available
as soon as practicable. The laboratories in New York have agreed
to supply us with a large quantity and they are proceeaino with
production rapidly. Additional supplies will he sent as soon as
I am

it

they are produced here.

Turan has suggested that I visit Istanbul on my next trip to
Europe. I have already made plans to be in Switzerland during
the period February l0 - 24. I would like to visit Istanbul during
the last week of February, arriving February 28 or 29. I will have
a more definite itinerary late in January.
Will you be in Istanbul during
to visiting you then.
My

best wishes for

that

week?

a Prosperous and Happy

May I
New

look forward

Year!

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

NF :

kp

‘
-.

a.
-,.
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i:

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—‘

�</text>
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                    <text>..,.

Sewn...“

.w

W

wag-WW...-

m

”mum-aw.

wwmw

V,

.

December 29. 1967

Mr. M. Kietzman

Biometrics Research
722 wast 168 Street

New

York, ﬂew York I0032

Bear Mr. Kietmaan:
Thank you very much for your letter of invitation and
the program of the Biometric Research Workshop, to be heid
February I3~IS. Whiie I wouid Iike very much to attend this
conference, I find that I have aIready accepted another
invitation to participate in a program in Europe. In the
event that I am unabie to make that trip, I wiII caII and
confirm my attendance.

Thank you once again

for your kind invitation.
Sincereiy yours;
Max

Fink, EH}.

Professor of Psychiatry

Mszp

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                    <text>{‘7'

:w-VI’v-I: .-.

7-K.

1r»

'T—m mwv'r-

-

a

.w

as «w- &lt;v w.»w~.-..V,-mv---m-we ,

~

“4“:

.

.

.—._-

rg...‘w-;;me WV» mu."

2»

.

‘1'

w

u m

war-—

December 29, 1967
Dr. Leon 0. Hankoff

Director, Department of Psychiatry

Queens Hospital Center
Queens General Hospital

82-68 l64th Street
Jamaica, New York
Dear Leon,
Your

visit to this

department was a stimulating one,

my associates and I have been encouraged to continue
our explorations in the development of a community based

and

satellite center. Please accept the

enclosed honorarium
and
token
is merely a
grossly unsatisfactory as a
fee for your services.

which

My

best wishes for the

coming

year.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp
enc.

�November 1, l967

Dr. Leon ﬂ. hankoff

Director, Department of Psychiatry

Queens hospital Center
Queens General Hospital

l64th Street

82~68

Jamaica,

New

York

Dear Leon,
Thank you very much

for accepting our invitation to share

staff at the Mental Health Clinic, your impressions of
a psychiatric satellite clinic eleItion. As I mentioned, I am
interested in having observers of the Mental Health Clinic share
their experiences with my staff, as we struggle with the develoo»

with the

this Hospital. The meeting will take place
at Metropolitan hospital. 97th Street and Second Avenue, on
wednesday, hobemher 15, at l0:00 am. We will meet in the clinic
on the lSth floor. The meeting will be quite informal with a
ment of a program in

,

probable attendance of twelve to

fifteen staff

members.

Following your request, I have asked Dr. Robert Sharoff to
meet with you earlier at his office on hard 15A. This is one
of the psychonharmacology study units and is dedicated to the
study of new drugs in the treatment of addicts. He will share
with you his extensive experience in many treatment attempts
with this population. I am taking the liberty of enclosing a
copy of the report which has just appeared in the J.A.M.A. Which
describes our most recent experience.
would be pleased to tell you of.our more
studies that have been suspended
because of.a shortage of medicatieo - a shortage which I hope is
temporary for this work has been most exciting.

If time permits,

recent

I

work with naloxone «

Thank you

for your willingness to visit with us.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry'

Max

.Mszp

'

�</text>
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                    <text>December 29. 1967

Subscription Department
Ha1ter J. Johnson, Inc.
111

New

Fifth

Avenue

York,

New

York 10003

Gent1emen:

that

subscriptions may have discontinued
grateful if you wou1d check your
inadvertantiy.
records and indicate the subscriptions which are either
active or inactive which are in my name at either my present
I be1ieve

address,

my

39

my

I wou1d be

Arieigh Road, Great Neck,

former address of

or 94 Lake

11

Forest, St.

New

York 11021,

Bayview Avenue, Great Neck.
Louis, Missouri 63117.

Thank you.

Sincere1y yours,

Fink, M.0.
Professor of Psychiatry

Hax

Mszp

or

New

York,

�</text>
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                    <text>I

wwww—ppg!

~

.

am-mwmr-mnwyu—nun—.www

'

.

vwmw‘rw-«vm&lt;

W'nw'q'

*Iovenber 1, 1957
Dr.

Carl Salmsh

ECDEJ, Paydmophannaooldgy Research

Brmh

National Institutes of Mental Health
Bethesda, Maryland

DearDr. Salman:
Thank you for your letter of October 2%. The list of studies
cmrently in progress has been markedly augmnted during the peat
few months. Enclosed are copies of research plan mporte for each
of the studies omehﬂy in progress and those that will be uhder~
taken during the next two Booths .

»

two oyolazoojm audios, the first in narcotic addiction
has been ompleted and two reports have been prepared. One has

0f the

Mean

seams Macadam during:
appeared in the Jamal”. 05 the
the past month and the second is in press in the humane Jamaal
05

first study of cyolazoome in depressive disszich. being- mleted
suit the second has
already been

orders is
planned.

The

now

The fluphehazine decorate stmiy is in progress , with the
protocol having been mdified so that after 20 cases fluphenszire
shah-triﬂe will be introduced as a omparstive drug.
We have recently begun to use the biometric laboratory form.

‘

.

to have you and Bill
13le
discretion.
I

a

would be

I look forward to seeing you
I

3.1:

(Buy

visit with us at

San Juan.

Sincerely yours ,
Mswaink, Mi).

‘

Professor of Psychiatry
_

your

�</text>
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              <elementText elementTextId="31062">
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                    <text>Nevember 20. 1967

“aw

Dr. Donald F. Kle1n

n1rector cf Research

V811iside Hosp1ta1
G1en Oaks. New York

08!? 90“.“
In requnse to your request. enc1osed 1s a 11st of‘my
pub11cat1ans. All the pub11cat1ons between 1955 and 1963
resulted {ram wcrk at H11131de Hospital In add1t1on there
‘are citat1ons 15 1953. 1964. 1965 and 1966 wh1ch are marked
1n the 11st. uh1ch are predom1naat1y the resuit of work done

at

aini
q-

W;

H111s1da Hosp1ta1

*5

1*

.

Sincere1y your3.

V5-

V

3
11“;
_

"a

3‘15."

; 3!§?'&lt;tf

7

Professar of Psychiatry

_..
,gM_~
4M—

1’"

.

«3

‘

b y
NWmM
.9

3"
2;”.‘1‘;'

'

MF:kp

“

1.139%

.,1,'

1
"91.9%,..‘45;

:2lHﬁﬂﬁ

r,
-

7.1

.(
V‘s“ W»;—
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(H

,9“.
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.

:ﬁr,

�</text>
                  </elementText>
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r" vx-r- ww-xu-

’Wp‘WI-WF'HM'MV

w

ww'Wv-x-x

av»
‘T‘VF‘,‘¥ZV*I‘i‘w‘wwnllm-ww‘,w~~

-

"7.":"m‘limwww-m&gt;1.

hoVembor

l,

V7-I-‘ﬁ‘m'yn-v—Vuw-0.1.9....mr ,

n...

“a“: ,7... amp.“ ,wwwmnnquw—am

1967

‘Dr. Leon D. Hankoff

hirector, Department of Psychiatry

Queens HOSpital Center

7

'Queens General Hosoital

82~68 l64th

Jamaica,

ﬂew

Street
York

Dear Leon,

for accepting our invitation to share.
Mental
Health Clinic, your imoressions of
of
the
staff
a psychiatric satellite clinic operation. As I mentioned, I.am
interested in having observers of the Mental Health Clinic share
their experiences with my staff3.as we struggle with the develoo~
ment of a program in this Hospital. The meeting will take place
at Metropolitan Hospital, 97th,$treet’and Second Avenue, on
Wednesday,~Nohember l5, at lD:OG am. we will meet in the clinic
on the lSth floor. The meeting_will be quite informal with a
orchable attendance of twelve to fifteen staff membors;
Thank you very moon

with the

Following your request, I have asked 9r. Robert Sharoff to
with
meet
you earlier at his office on hard lSA.‘ This is one
of the psychophannaoology study units-and is dedicated to the
study of new drugs in the:treatment of addicts. He will share
with you his extensive experience in many treatment attempts~
with this population. loam taking the liberty of enclosing a
copy of the report which has Just appeared in the J.A.M.A. which.
describes our most recent experience.
-

'

time permits, 1 would be pleased to tell you of our more
work
with naloxone ~ studies that have been suspended
recent
because of a shortage of medication ~ a shortage which I hope is
temporary for this work has been most exciting.

If

'

Thank you

for your willingness to visit

With us.

’Sinoerely-yours,

'

MF:kp

Max Fink, M.B.
.Professor of Psychiatry‘

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~

‘

M

‘vh‘hkm

‘W W

..

M"

“W“

»

~m..“mmmmme—VWW.mvmwmwmm.wmmwm mwmmw

{I}

November

2,

1967

Dr. Joseph 6. Bird

Director, Division of Clinical Research
Steriing~winthrop Research Institute
Rensseiaer, new York 12144
Sear Joe,

of a

this

As yau know, we have carried out some preiiminary studies
new narcotic antagonist, naioxone. The EEG patterns of

compound

are different frcm cyciazocine.

data is quite similar however.

The

clinical

you or any of your associates are interested in
attending, I wouid be pleased to see you at the meeting..

If

q
My

best regards.
Sincerely yours,
Max

Fink.

M.D.

Prcfessor of Psychiatry

Hszp

“Vim“...“w‘”

�</text>
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                    <text>november 3, 1967
Mr. Henry L. Giordano

633 Indiana Avenue, N.h.
Washington, D.C. 20226

Dear Mr. Giordano:
stamp

Enclosed is an application for registry and
spacial-tax
for a marijuana permit, class 4.

This application is submitted
the suggestion of the
National Institute of Rental Health at(Dr.
Jerome Levine) and
the Chairman of this Department of Psychiatry,
Dr. Alfred M.
Freedman. Since l953 I have carried out
intensive studies of
the effects of a wide variety of psychotropic
drugs on EEG and
behavior. The present laboratory at the new York
College
is the third under my direction. This laboratory Medical
is
specially
equipped to carry out studies on the duration of action
of psycho~
active compounds. and the intar»relation of changes in brain
function and

behavior.

Recently,

we

,

have studied

narcotic

and

anti-narcotic

interest in marijuana and the availabilitycompounds.
marijuana extracts, we have made application to the National of
Institute of Mental Health for supplies for these experimental
With the present

studies in volunteer subjects.
Thank you

for your cooperation.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>November 3, 1967

Miss Gertrude Samueis
New York Times
New

York.

New York

Bear Miss Samueis:

is

This presentation of a nave} treatment of narcotic addiction

a preliminary statemant of the

to attend.

availabie data.

You

Sincereiy yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

are weicome

�</text>
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                    <text>.
..

_,

_A

0...”,

‘nwvtw

Hovamber 3, 1967

Dr.

Fietchar

Owens

A. H. Robins Campany
i407 Cummings Drive
Richmond 20. Virginia

Dear Dr. Owens:
The initial supply of Tybatran
November
1. I want to thank you
on

capsules. 250 mg, arrived
for this supply. and for

your cooperation in obtaining a suppiy from your iocai distributar.
He was kind enough to deiiver Tybatran, 359 mg capsuies, sufficient
for the next week of the study program.
Three patients have already been in treatment siace October 26,

and two additional

patients

W".

Thank you very much

-7“.

began on ﬁavember 1.

for your couperation.
Sincereiy yours,

‘wwv,‘_n

..

qw-mww-y—‘W.

Fink, M.D.
Professcr of Psychiatry

Max
.w-rpa

"a“

..
4
w»

“rm-n”

Mszp

‘

�</text>
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0r. RaIph Jacabsen
Associate Medicai Director ,
Ends Laboratories. Inc;"
1000 Stewart Avenue
Garden City, New York 11533

ﬂavember 3,’1967’

'

sear-Dr. Jacobsen:
Enclosed is an announcement of the presentation of the‘
naioxone’data at Metropolitan HOSPitaI on ﬂovember 10. Yen
and your associates are-weicome to attend and I hope t9 have
the opportunity to discuss-the presentation with you.

Sincereiy yours.'
‘

Prefessor of Psychiatry
Mszp

'

�</text>
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                  <elementText elementTextId="102366">
                    <text>cqﬂr- xv

n.

n ,

, «u..-

-—-

11.»th ..

-

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r.

.

w ..,,

”may...“

1-:Vz '.w'g-A:’

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.7

.-

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:1gﬁuv-i_.cr.Inn—PIN“

,

7

.

.

.

,

.
_

.

r

.

November

_

exal’ﬂww'vr)ﬁﬂ‘u'9x--I'wl"':

m,wwwwrwmwvmmrnwv-gm aw arm-um

6, l967

Dr. Lino Covi

;

E

3

!

i
f

i
i
E

5

E

i

i

E

g

i

%

i

E

Assistant Professor of Psychiatry
The Johns Hopkins

University School of Medicine

60l North Broadway

.

Baltimore, Maryland 2l205

Dear Dr. Covi:

It was a pleasure having you visit with us today. This is
to confirm the procedures which might be implemented subject to
the agreement concerning the protocol by your staff and Dr. Donald
Shapiro and myself.
We are equipped to undertake the
analysis of the necessary
records in 100 subjects half of whom are to receive Bilantin and
the remainder a placebo for periods of two months. he would
recommend that EEG records be obtained on two occasions prior to
drug treatment and a single record at the end of four and eight

wee

s.

We will provide the results of period
as described
analysis
in the attached report with the outputs availa
e in printed form
and in data cards.

it will be necessary that
electroencephalograph which is linear in its
output on magnetic tape up to 80 cycles. frequency oscillator, two
channel oscilloscope, and a l/2 inch FM tape recorder compatible
with the SP~300. he would like to recommend that you use Ampex
746 l/Z inch tape or its equivalent.
If such a study is of interest to you and your associates, I
would be pleased to discuss with you the additional costs of data
analysis and consultations.
To accoMplish

you have

available

this study, however,

an

,

-My

best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

.w-r; v-:_.:

on:

W;

m;

m-m-r,

an an. my

23

(an, m.-

�</text>
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                    <text>mm «vs Hw wwwummmwuwwawww"':~‘l-

‘vin' my van-,|-:-*-n--n1-w.w m«m.vg...; 's’usﬂm-memw

w ‘m‘n-‘mw'nvm

www.mwrx-ruvm-mr

W'vv

um nurwmuwm‘mﬁﬁ

ﬁovember 8, 1967
Dr. Joseph G. Bird

Sterling Hinthrop Research Institute

Reasselaor,

New York

12144

Dear Joe,
We are continuing the present cyciazocine ~ depression
study and are in need of additionai supplies of cyc1azoc1ne
placebo. Would it be possible to provide us with an additional
ton bottles of placebo (50 tablets per bottle)?

Many

thanks!

Sincerely yours,

Fink, M.D.
Professor of Psychiatry

Max

‘

I'ern-rr-w'rew

I.

"Maw

arm-Wu

W'mm'mwrﬁmm

7

mmrv-xﬁs'v

‘
_

MF:kp

.u-wv

'v

w rum

--

arr,

sv‘u w

'F‘s‘“

�</text>
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                    <text>November

Dr. Norman E.

8, l967

Pitts

Associate Director

Chas. Pfizer a 60.. Inc.
Department of Clinical Research
Grnton, Connecticut 06340
Dear Dr.

Pitts:

‘

study of Doxepln is continuing actively and we are
additional supplies. Would you be able to send us
of
Doxepln, 50 mg (100 capsules per bottle)?
l0 bottles
The

in need of
Many

thanks!

Sincerely yours,
Fink, ﬁ.0.
Professor of Psychiatry

Max

Mfzkp

Please ship to: Dr. ﬂax Fink
Department of Psychiatry
New

5

York Medical College

East lGan Street

New

York,

New York

l0024

�</text>
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                    <text>m

V

mun—n.

“symmvww

——

WMMJWZVW‘mwrwnr-wn

row

'WF

November

8;

1967

Dr. Paul Kay

l5 Canterbury Road
Great Neck, new York
Dear Paul.

calendar for February l968, and find
conflict.
recess_f0r the schools in Great Neck
lo -.24. and I have planned to
in
the
February
occurs
period
take my family on a ski trip to-Swltterland. It will not be
possible for me to participate in the meeting of February l9.
a

I have

Just

Checked

The Spring

my

regret very much this inconvenience, but would be pleased
to suggest other members of the Soclety‘as,a discussant. Unfor—
tunately. I had hoped ta carry an a dialogue with Dr. Klerman and
extend your explorations into new formats for the mcetlng.
I

Please call

assistance.

me

at your convenience if
'

I can be

of

Sincerely yours,
Max

fink, ﬁ.D.

Professor of Psychiatry
ﬁF:kp

any~

�</text>
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5

L

Hovomber

Dr. Leo

8, l967

Hollister

Veterans Administration Hospital
Palo Alto. California 94304

Dearvtoo,
I read your report on ST? in the latest issue of Science
with great interest. Since the first reports that chlorpromazino
ur—nwi

accentuated the clinical effects of STP. it was apparent that. if
these reports were true, then STP must be more similar to Ditran
and atropine than to LSD and moseoline. Your report clarifies the
apparent discrepancy between the pharmacological data in the press
and the statements from the FDA.

.vyrrmw-r

(if

pm

ow.

raw

WWI"

armmuvmw

cw

esoecially interested in using
and important discrimination.
YoUr report in Science notes that EEG records were done prior to
drug administration. More these repeated during the drug period?
If so, were the changes consistent with any of our reports of EEG
changes with anticholinergic and sympathomimetic hallucinogens?
Incidentally, thank you for your comments on Oxypertino.«
I
If can get some for EEG trials, I will surely lot you know
what we find.
our

I am

EEG

writing because

methods in

we

were

this difficult

Sincerely yours,
wva-ap-wmvxwya-nur-u-r-WWV

Fink, $25.9.
Professor of Psychiatry

{t‘ax
wy-vr-w-u-vw

HF : kp

m—m‘JP"

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                    <text>-

ﬂy“.

Mrr/"",.|‘:uA

1.7.x,“

..._-&lt;..-Aw.w—i

wt v“? ‘1

\er..vA-.F'm‘. :wv

--r~«,n-

‘-'~-w‘.':.‘slur.lm:

wan' .7“

November 8, l967

Dr. T. P. 5. watts
Geigy Pharmaceuticals

Ardsley.

New York

Dear Paddy,

In the interim of establishing the ketimipramine and the
cyclazocine/imipramine studies, we are in need of additional
supplies of imipramine tablets (25 mg). Would it be possible
to send us l2 bottles of Tofranil 25 mg (100 tablets per bottle)?
Thank you very much for your cooperation with Dr. Bird.
that he obtains the necessary documents for you shortly.
so that a definitive study can be undertaken.
I hope

I note that you will be in Houston at the end of the month.
I do not think that I can make this meeting, but one of my
associates, Dr. Luigi Bucci,will attend and I have asked him

to listen carefully.
My

best regards.
Sincerely yours,

:1
w-

mr'niub’

Fink, ﬂ.3.
Professor of Psychiatry

Jymrlnva'nwvvr

Max
,Wy

.&gt;

w—su-‘Wmn’ﬁx

xv.

Mszp

�</text>
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              <elementText elementTextId="30932">
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                    <text>9r. A‘bert,J. SilverMan

'

November 8, 1967

Professor and Chairman
Rutgers a The State University
New Brunswick. New Jersey 08903
.

‘Dear A],

NhtIe I have knawn Dr. Kiramftci for some years, our
association has been axclusively 1n the Inboratcry. We had
no medical students in St. Louis; and the residency training

,,

«WV

.
‘

was

_,

a

‘

‘

principalTy by individual lectures.

..

'

‘
_.

¢

Sincereiy yours,

‘.

4

w”-

r
h

Max

Any-q.“

—-

-H’L*;r‘

"mm-“n

I
~

..

any.»

“1.40%",

v

‘
A

,.
v

v-.,:ur.mv,»

n'nfl-lrr'.arr-"‘1—'wn&lt;

1$rwm._..rw.rmw;rv

:1"

r4

au-

arm,

«v.

V:

Fink,

M.D.

Prafessar 0f Psychiatry

«.

Mszp

�</text>
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                    <text>n

._

"Var

«av/~-

"ww1-w

‘01:

w».

a

”gm...ﬂ,.,,,...

9m

“A,” “wan—QVWWTE ”ﬁr.,hmm_--Rxl.L‘—v-~,WF ‘pm-nm—m-wxuvwcIwmow-meam

ﬁr:w'y}"&gt;:‘r“'w""}\1

November 10, 1967

Center for Professional Advancement

P. O. Box 66
Hopatcong, ﬂew Jersey 07843
Gentiemen:

I have read of the proposed conference on drug discovery
and deyeiopment in a recent issue of the Dang Inéommazion
, and am writing far a more campiete description of
:

the program, inciuding the projected dates.
'Thank you.

Sincerely yours.
Fink, M.D.
Prufessor of Psychiatry

Max

mrzkp‘

rmw \uwerov-wnuvuwwx,

V

I‘

.

,

—.

,

a m- .

.v

,

�</text>
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                    <text>Nomnber l3 , 1967
Dr.

J. a. van-team

Rutgers -~ The State Univemity
New Bmmuidc, New Jersey
Dew Dick,

Wmtfnmiptsforthasympoeiunon

depression for the fcx'timning mm meetings. The copy
submitted is Maplete, laddng the ﬁgures. It is

suitable for discussim and Dr. Itﬂ and I will Wait
a draft suitable for publicatim at the tin: of the meetmg.
Sincerely yours ,
Pink, H.D.
Nasser of Psychiatry

Max

Mszp
cc: Dr.
Dr.

121m
11:11

�</text>
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                    <text>mgwxmwmwmva. :11‘

,mv'lmsmurn‘vr"&gt;m—cx-.

m

“wmq‘wm'n

rpm yaw...

...

.....mx-wv-v

,‘4

.7.”

.r—wugn-Wﬂq-r

_

November

Dr. Ralph Jacobson

Associate Medical Director
Endo Laboratories. Inc.
l000 Stewart Avenue

Garden

City.

New

York l1533

Dear Dr. Jacobson:
Dr. Freedman and I are pleased to join you and your associates
on Wednesday, November 22. Unfortunately, both he and I have
commitments in the morning that would not permit us to arrive in
time for lunch and would prefer to meet about 2:00pm.

Enclosed are three copies of the summary statement of our
experiences with naloxooe as prepared for the staff presentation

Perhaps. it would be helpful if this were
available to some of your associates prior to our meeting.

on November 10.

Sincerely yours,
Fink, “.0.
Professor of Psychiatry

Max

.»

,»

Tawny-msqu

m-n

l4, l967

MF:kp

made

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                    <text>Nmnber lit ,

1967

Br. 'Ibmn M. 11:11
Missouri Institute of Psychiatry
5M0!)

metal

St. Louis,

Street

Miami

63139

Dem'mmn,

Bmlosedisadmftoopyotﬂwemportmentidepmemta

fwmfmlnmﬁxgmmﬁm. Imuldbegmtefulifym
maid review this carefully and make any necessary ametinm
mgaxdingfigumsthatmﬂdbewiate.
Inmplytoamqmstfrmm.lahmm,1ruvemmpies
ofthiedmft,euitab1ymaﬁaadmpmmdmy,mm.w1ttenbmm
for the participate at the

8mm.

Again,mybest.
Sincerely yams ,

M My ”CD.
of

£5:ch

Psychiatry

�</text>
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          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Correspondence</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="30874">
                <text>Correspondence to: Itil, Turan M.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="51">
            <name>Type</name>
            <description>The nature or genre of the resource</description>
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              <elementText elementTextId="30875">
                <text>Text</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="30876">
                <text>mfp-05-00-021-8-503</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30877">
                <text>1967 </text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30878">
                <text>&lt;a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank"&gt;Fink, Max, 1923-&lt;/a&gt;</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="30879">
                <text>Correspondence -- Correspondence</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
            <elementTextContainer>
              <elementText elementTextId="30880">
                <text>The Max Fink Collection</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="30881">
                <text/>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30882">
                <text>&lt;a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank"&gt;IN COPYRIGHT - EDUCATIONAL USE PERMITTED&lt;/a&gt;</text>
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            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="30883">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="77290">
                <text>en-US</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="42">
            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="83851">
                <text>application/pdf</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="90412">
                <text/>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="37">
            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="96973">
                <text/>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
    <tagContainer>
      <tag tagId="4">
        <name>Correspondence</name>
      </tag>
    </tagContainer>
  </item>
</itemContainer>
