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April 28. 1969
Dr. 6. Richard Hendrick. Ph.D.
Arthur 0. Little. Inc.

Acorn Park

Cambridge. Massachusetts 021d0
Dear Dr. Handrick:
Thank you very much for the analysis of our sample of
It was most useful having the assay from ﬁrs. Manion

A9-THC.

and Efren.

It is

my

interpretation of the data that there

has been a degradation of the a9-THC and for practical purposes
reduction has been approximately 10% with increasing amounts
appearing as a“ and N-3.
In retrospect a possible explanation for this degradation
has been that our samples have been maintained at approximately
5°C. which may not be adequate.
we

are very grateful for your help.

"Yﬁmwxwmamm

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max
rtwcsz-wmn

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                    <text>r“. W,,,

“m“, _,,,,__

,

W.1w_.wmmmwvmn
,

r

, .4,

”w.—wm.mw Wu ”Wm
. we ..._ .

.

M

’w-W,_mnu._ww .w e—inww—n—r W

Wr'w—v-«mm‘lﬂ-v-mm

w!

v

m—mmmAW—‘VW~N,—

April 28,1969
Miss Ellen Kaplen
E. R. Squibb 3 Sons. Inc.
909 Third Avenue
New York, New York 10022
Dear Miss Kaplan:

is

a revised summary. including all the
you suggested. in only one instance (VI) could
I not follow the suggestion - and this because my notes
indicate this to have been reported. and not to be in his
be from another reference of
written report. Could
Simpson's not known to me? Perhaps you would send the
paragraph to him for his comments.

Enclosed

corrections

it

I presume you

don't wish the xerox copies of the
if so. they are in the file.

papers returned. but

Sincerely yours.
ﬂax Fink, M.D.

Professor of Psychiatry

�</text>
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                    <text>[We

NWT—"y".—

(212) 369-7900 Ext. 245

April 25. 1969
Mr. Robert L. Marlin

Sandoz Pharmaceuticals
New Jersey 07936

Hanover,

Dear Mr. Merlin:
I have read the preliminary data on Sandoz 42-548
with
interest. It is possible that we can undertake an EEG profile.
but the earliest wouid be after the summer holidays.

I am enclosing

reprints describing our work as well as a
report of our observations in another anorexigenic.
fenfluramine.
preprint of

a

a

As an example of our approach
study of another compound.
As I

would you

I am

enclosing a protocol of

will be out of the country from May 2 to May 20,
my office and arrange to visit soon thereafter?

call

Thank you

for your interest.
Sincerely yours.
Fink, M.D.
Professor of Psychiatry
Max

MF:kp

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                    <text>April 25. 1969
Dr. Arthur H. Epstein
1430 Tulane Avenue
New Orleans 12. Louisiana
Dear Arthur.

find that I will not be able to attend the American
Psychiatric Association meetings. and I am listed as Chairman
of the session on biological psychiatry. As cowchairman will
you accept the responsibility for the session?
I

If you find that you are unable to be at the meeting,
would you please arrange with Dr. Rothrock to be chairman?
Sincerely yours.

lax Fink,

M.D.

Professor of Psychiatry

ﬁF:kp

�</text>
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                    <text>~

‘m

me'wmn

—_ WV... WY“

April 24.

1969

Dr. Moressa H. Orzack

Boston University School of Medicine

Division of Psychiatry

80 East Concord

Street

Boston, Massachusetts 02118
Dear Dr. Orzack:
I

Thank you very much for your letter and curriculum vitae.
very mach admire the work of Drs. Mirsky and Kometsky and

I am

interested in similar applications.

It would be very helpful to have you visit this laboratory
at your convenience. Unfortunately. I will be away from May 2
through May 20, but if it is possible to visit before May 2, I
shall gladly set aside the time.
Please call

my

office at (2l2)

369-7900 Exg. 245.

Sincerely yours.
Fink. M.ﬂ.
Professor cf Psychiatry

Max

�</text>
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                    <text>April 23,

1969

Mr. Don Choctham

Smith, Kline

&amp;

French Laboratories

Philadalphta, Pa.
Dear Don,

for the oxcellent survey of Manifontations of
Dermatitis asaocioted with 'Thornzine'. The roferencas did include
some that I had not found, and I am now, more than over, prepared to
Thank you

dofond the proposition which has become the subject 0! a court
Many

trial.

thanks.
any chance that you will be in
opportunity to V101: our liberatorieu this

Incidentally, is thoro

ﬂew York and have an

spring

?

Sincerely yours,

'

Fink,
Professor of Psychiatry

Max

M.D.

.

Diroctor. Division of
Biological Psychiatry

�</text>
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              <elementText elementTextId="37321">
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              <elementText elementTextId="37323">
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                  <elementText elementTextId="105731">
                    <text>)'~=Wv'1'rl“»’"4

("WY

new,”

7

m.

..

T0:

Dr. A. h. Freedman

FROM:

Dr.

SUBJECT:

Dr. Frederick Beekeland

Max

DATE:

April 23,

1969

Fink

and I have had an opportunity to meet
and
to discuss his proposed program.
Dr. Baekeland
ﬂy

associates

I found him knowledgeable.

experienced but tense and

anxious.
principal interests are in sleep research with
the
manipulations of deprivation of various stages
on
emphasis
and
there effect on mood and effect. He expressed
of sleep
of sleep research except a passing acquaintance
outside
no interest
His

with alcoholism.

principal activities at
in teaching medical students.
His

Downstate Medical Center

is

Impression: Considering the large number of sleep researchers
I am not impressed that he has sufficient novelty in his approach
research.
or enthusiasm to warrant appointment in this area of
I found him to be restricted in his interests and I wouid wish
to inqdire of his superiors at Downstate whether this restriction
does not carry over into his teaching.
MF:kp

�</text>
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                    <text>——‘-w

wr'

pvv

w.

—u-.--«.yv

WWW&lt;

April 23. 1969
Dr. Jonathan 0. Cole
Superintendent
Boston State Hospital

Boston, Massachusetts 02124
Bear Jonathan,
I am very

very grateful for your enthusiastic

letter

regarding the ECT Manual. Your request for so many copies
and your suggestion that it be published led me to review
the manual and I have made a few modifications. particularly
in the theoretical sections. This is being typed and I am
going to submit it to the American Journal of Psychiatry, hoping
that they will accept their educational Tbnction.
which

In the meantime, I will arrange to run off 50 copies
be sent to you within the next few weeks for

will

distribution to your staff.

Sincerely yours.
Fink. M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>hpril 23.

1969

Dr. Ivan F. Bennett
Illly Research Laboratories

The

Eli Lilly and

Company

Indianapolis. Indiana

46206

Dear Ivan.
I regret that our paper "d-cyéloserlne 1n the Therapy of
Psychosis“ has not been published. The draft sent to you has

not been prepared for publication.
Thank you

for referring

Dr. Thomas

pleased to answer any questions that he
My

to us.

may

and I would be

have.

best regards.
Sincerely yours,
Fink, h.D.
Professor of Psychiatry

Max

Mszp
.-

.m.

.‘Twnwuwav

a.7,.....~.--v.«worm—l

,‘

,.l.

�</text>
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                    <text>April 23, 1969

Sesata
Sales Representative
The New York Hilton
1335 Avenue of the Americas

Mr. Joseph E.

New

York,

New

York 10019

Dear Mr. Sesata:

Following our discussions and your memorandum of March 28,
iike to reserve the Mercury Bailroom and Promenade for
meetings of the American Psychopathoiogical Association on
Friday. February 13, and Saturday, February 14, 1970. would
you piease arrange the necessary documents for our signature?
we

would

Sincerely yours,
Fink,
Secretary

Max

Mszp

M.D.

�</text>
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                    <text>April 23, l969
Mr. James

J. Flanagan

Director of Sales

The Park Sheraton Hotel
Seventh Avenue and 56th Street
New York. Haw York 10019

Dear Mr. Flanagan:
The Council

of the American Psychopathological Association

is desirous of changing the format of its

program and

for this

reason request cancellation of the meeting to have been held
at the Park Sheraton Hotel on February 12-14. 1970.
I wish to take this opportunity to thank you for
your
splended couperation during the past many years.

Sincerely yours,
Fink.
Secretary
Max

MF:kp

H.D.

�</text>
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                    <text>April 21,
Dr. Torso

1969

Itil

Profoaaor of Psychiatry
Missouri Inatltute of Psychiatry
St. Louis, Missouri

Ref:

CP~

l&amp;,368

Dear Torso,

For some time I havo expressed tho desire to examlno
potential psychoactive compound in the EEG analytic scroen,
without tho utual animal or clinical olues, which could influence
our EEG evaluations. Dre. Betas: and Pitts of Pfizat Medical Research
Laboratorlen havo mods such a otudy possible. and I am writing to ask
your assistance.
-

a naval

‘

Enclosed is a cepy of tho available animal and clinical
pharmacology data, an augplitd by Dr. Berger. 1 would be grateful
for your reviuw of this notorial and your toaponse to the following
question:, which I propose to use in formulating a daftnitlvo pilot
A: I would like to start with singlc, oral dosagao in young
study.
(21»35 yearn) male voluntoero, the questions aro:

what dosage should be tasted
what incromonts should be tested ?

initially

?

If

no

effect,

‘rr'r‘n

~

tear.

a

egfocts

7

At what time
What

~svr¢x,ys;rﬂf”vrt=v'm,~

-'

é

in the

reviaw of the data

intorvala can
maximum dose

7

-'

.

*

r-‘u.~"

«damp

a;
~19

anticipato clinical and/or

that should

EEG

be toatod beforc your

effects should ho tested for most carefully 7
secondary effects are experienced, what are the prohibited

what secondary

Aneuming some

antagonists? the preferrod,

”

wt

What

if

are the primary

known ?
EEG

leads to be examined?

Any behaviorol questions that may be anticipated in addition
the
one: included in the Clyde Mood Scale, which we have used in
to
these studies to date ?

�'-

x

{A

1:11

0

I

I

a

o

I

o

0

2

a

I

O

.

.

.

.

.

April 21,

I would like to begin these studieq about June 1, and would
appreciate the opportunity to discuss this with you beforo the APA

meetings in May.
Many

thanks, and

“\i.
"\x

my

best regards.

\.

\‘i
5

u

‘\

\\

Sinceréﬁy yours,

Max

Fink, M.D.

1969

�</text>
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                    <text>April 21,
A

1969

Dr. Allen P. Berger, M.D.

Pfizer Pharmaceuticals
Groton, Connecticut
Dear Dr. Berger,

on

CP—

Itil.

I have rovicwod tho letters and the clinical data shoots
larger folder to my consultant. Br. Toron
Tho FD
1A,368; and cent the
1572

is onclooed.

Before completing a proposed protocol. I would like to have
the benefit of Dr. Itil'a comments. It will also be notes-ary to £11:
a protocol with our College authorities.

I note in your letter a desire to undertake this study before
the end of April. I regret that such a timo~tablo is not foaaiblo since
I would like to carry out thoue studios myself, and I am committed to
a oonforoooo and none pita vioito in Europa from May &amp;«20. we will be
able to run our initial trials during the first week in June and carry
out some of the exporimonts until late July when I anticipate a oumnor

hiatus.

I trust this

timo schedule

is acooptoblo.

ﬁany thanks for the Opportunity to review the notes and to
propose a study of CP~14,368.

Sincerely yours,

Fink, M.D.
Professor of Psychiatry

Max

mf/

�</text>
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                    <text>April 21, 1969
Dr. Norman

Pitts

Chas. Pfizer &amp; Co.
Groton, Connecticut
Dear Norman,

.‘

Would

«my...

‘:uF?--mt,w~‘

it

be possible

for

us

to receive

3 x 100

are completing our Doxepin study

capsules placebo?
and I think this would be sufficient until termination.
We

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
5;.

a;
«1;

1a
1*

“"1

MF:kp

war?

“55.13"”

’.“I'-F*£VW?¥'?"

aw

magewmwmmmr

gag/‘22:

~.
122;?

g;
y
‘,

ru‘vrn

-

\
wu-

V

..,'

”wan,

mama;

"1

W‘s:

Fl

�</text>
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W

,

mm'mwvw mnwymwmwwﬁ—u-m..

W

sum-nun“.

April 21. 1969
Dr. Edgar Grunwaldt
Geigy PharmaceuticaIs

Ardlley,

New

York

Dear Ed.
Our ketim1pram1ne study is continuing and we would
appreciate 10 x 100 placebo GY~2277.
My

best regards.
Sincerely yours.
Fink, H.D.
Professor of Psychiatry

'71.».qu

Max

A

MF:kp

—

�</text>
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April 18. l969

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Dr. Richard D. Halter

International Congress

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Dear Dr. Halterm
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two

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begun in

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r“
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Fink. M.D.
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Max

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Dr. Richard D. Walter
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Neuropsychiatric Institute
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                    <text>raw-ran

«aw

{mm‘rr.'='w'v"

April 17. 1969
Dr. Edgar Grunwaldt
Goigy Pharmaceuticals

Ardsley,

New

York

Dear Ed,

time ago you requested that ketimipranine be maintained
longer than 6 months in continuous treatment. We reviewed
our casewload and the 6 patients in extended treatment were
transferred to other antidepressant therapy. They ranged from

for

3%

Some

no

to 7k months

on

ketimipramine.

In reviewing the laboratory data we found similar incidences
of values outside our established limits for ketimipramine and
placebo. The incidence of out of range values for this sample
is no greater than that observed in this clinic with other compounds,
includ ng cyclazocine in similar groups of depressive patients.
The out of range values are circumscribed in red. The drug code
is A-K for active ketimipramine, P-K for placebo.
I

trust this data is useful.
Sincerely yours,

«qr—mm

rruruw

am

Max

r"

v,rY"‘-"

Professor of Psychiatry

tavm'ruu

wtr-yvzw

F‘nk . ”o D.

Mszp

�</text>
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                    <text>.

V

.-.,.«-w~-w.-W-~-r~r‘w1-m‘m.u.m.m“mm-7.." .u—v—wnvun .vuun u...» w—z—W~

..

,

.,,.,.,_,.

. m."—

w.-.wm,.

V.

“or“...

.,.v..—..__~n.

.w.

u.

7

,

,...

.

.

w

-.-.

Av

1
,

mm”?

7‘.

"mm.

April 17. 1969

war-r

Dr. E.

A

atix:3':ximmm‘

m

.n‘GWWZ-w‘w‘wu

\W.txw”‘vw.'v

\‘W‘.7

I“.

J. Preston

A. H. Robins Company
1407 Cummings Drive

Richmond, Virginia

Dear Dr. Preston:

Re:

Tybatran Laboratory

for not submitting the enclosed data
when
earlier. but the data has been misplaced until this week
additional
the
Enclosed
I reviewed our fenfluramine data.
are
records of laboratory tests in narcotic addicts assigned to
Tybatran treatment. The data filed earlier was that available
in patients who sustained treatment. Each of the patients in
I must apologize

the present group withdrew from treatment before repeated
laboratory tests were completed.

W?

Please add these records to those filed

r;

earlier.

Thank you.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

.

.

ﬂ

,

�</text>
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                    <text>«m—wu 0-w-

April 17. 1969
Miss Jane Brody
New York Times
New

York.

New

York

Dear Miss Brody:

pleased to enclose two reports, soon to appear from

I am

which may interest your readers. The work is
done
two
by
of our resident psychiatrists, Drs. N. Taylor
being
and R. Levine. and is of significance in our understanding of the

this Department.

pathogenesis of post-partum psychosis.

Two observations are clear: the onset of acute schizophrenia
in conceiving women inhibits (destroys) male offspring, for only
female infants are born to mothers who conceived within one month
of an acute psychosis; and. the onset of acute post-partum forms
of schizophrenia is associated with the birth of male infants.
Both observations are consistent with a concept of a hormonal or
immoral substance which stimulates an acute psychosis. transfers
from mother to fetus and is inimical to a male fetus. Further, this
substance is antagonized (inhibited) by_substances from a male fetus.

and come

Two

into active play.

after

soon

reports are enclosed -

a male

infant is delivered.

”Newborn Sex Ratios

Associated with

and Post- Partum Process Schizophrenia” has been accepted and is
soon to appear in Science; "The Interactive Effects of Maternal
Schizophrenia and G??spring Sex“ has been submitted to the Society
of Biological Psychiatry and will be read on May 3, in Miami Beach.
Pre—

I am

pleased to

tell

you

also that the Section of Neurology

of Medicine and the New York
Society for Clinical Psychiatry cited these reports as the best
psychiatric paper at the annual residents presentations in February;
and the Society of Biological Psychiatry will award them the l969
A. E. Bennett Clinical Science Research Award on May 3.
and Psychiatry of the

New

York Academy

The work was undertaken

in partial fulfillment of elective

requirements in then Division of Biological Psychiatry of this
Department. He may be reached at 369-8488 or 369-7900 (x 245)

for furhter information.
I trust this is of interest.

Sincerely yours.
Fink. M.D.
Professor of Psychiatry

Max

MF:kp

:n“

�</text>
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,.

4,

my...

April 16. l969
Dr. Richard Hendrick

Arthur
15

D.

Little

Acorn Park

Co.

Cambridge, Massachusetts
Dear Dr. Hendrick:
have discussed with Dr. Pars, I am sending you
be
ampule of THC with a request that
an
separately
analyzed for its content. This is one ampule of 50 that
we received from Dr. Albert Manian and Dr. Daniel Efron
of NINH. The ampules were marked as containing l0 mg THC
As we

per

2 ml

of

it

95%

ethanol sealed under nitrogen.

In some of our recent trials we have had less of an
effect than earlier and are anxious to determine if deterioration
has occurred.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>April 17, 1969
Miss Jane Brody
New York Times
New York, New York
Dear Miss Brody:
I am

v;
.4

.
.3.

“(&lt;1ng

pleased to enclose two reports, soon to appear from

which may interest your readers. The work is
being done by two of our resident psychiatrists. Drs. M. Taylor
and R. Levine, and is of significance in our understanding of the

this Department.

pathogenesis of post-partum psychosis.

Two observations are clear: the onset of acute schizophrenia
in conceiving women inhibits (destroys) male offspring, for only
female infants are born to mothers who conceived within one month
of an acute psychosis; and. the onset of acute post-partum forms
of schiZOphrenia is associated with the birth of male infants.
Both observations are consistent with a concept of a hormonal or
humeral substance which stimulates an acute psychosis, transfers
from mother to fetus and is inimical to a male fetus. Further, this
substance is antagonized (inhibited) by substances from a male fetus,

and come

into active play,

soon

after

a male

infant is delivered.

Two reports are enclosed - "Newborn Sex Ratios Associated with
and Post- Partum Process Schizophrenia" has been accepted and is
soon to appear in Science; "The Interactive Effects of Maternal
Schizophrenia and ﬁffspring Sex" has been submitted to the Society
of Biological Psychiatry and will be read on May 3, in Miami Beach.
Pre—

m-

1.
cm

;

513,729:

fﬁmgqms

tijwwwlpmwmp

'A'NWWWWW

pleased to tell you also that the Section of Neurology
and Psychiatry of the New York Academy of Medicine and the New York
Society for Clinical Psychiatry cited these reports as the best
psychiatric paper at the annual residents presentations in February;
and the Society of Biological Psychiatry will award them the l969
I am

A. E. Bennett

Clinical Science Research

Award on May 3.

in partial fulfillment of elective
requirements in the Division of Biological Psychiatry of this
Department. We may be reached at 369-8488 or 369-7900 (x 245)
for furhter information.
The work was undertaken

I

trust this is of interest.

“537»:

Sincerely yours,

Mr.

‘,"§E%§1Wﬂ,mf’f“fxtb

Fink, M.D.
Professor of Psychiatry

Max
'

:‘I‘EWi‘Wfflﬁ

('1'?

MF:kp

�</text>
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                    <text>_

w—VW

V

Aer

15. 1969

Dr. Kenneth Lifshitz
Rockiand State Hospitai
Orangeburg, New York 10962
Dear Ken,
Thank you for your inquiry regarding our paper for
the Society of Bioiogicai Psychiatry. I had hoped to
present some information from our pentothai data but these
analyses have been more protracted than anticipated. Last
month I withdrew the report.
As

soon as our present studies are completed I wiii

be giad to send you a copy.

Sincerely yours.
Fink. M.D.
Professor of Psychiatry,

Max

MF:kp

�</text>
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                    <text>{Ig&lt;'r-r

&lt;;&lt;;~j')‘vl-,‘

Mir-cur;

April 17.

m1.”

1,.

M17:

4'ﬂvrv;

‘ommmi‘

Mr.

J. h. Tielrooy

Elsevier Publishing

1969

Company

Jan van Galenstraat 335
P. 0. Box 211
Amsterdam, The Netherlands
Dear Mr. Tielroqy:

I am writing with regard to my subscription to the
Journal and your recent letter reminding me that my
subscription has run out. I have tried to arrange payment
through the New York Medical College and would like to tell
you that our records indicate payment send on March l
(check #29486) in the amount of $50.00. This check was to
cover subscriptions to the EEG Journal for me and Dr. Sidndy
Neinstein of the Department of Pediatrics of this College.
EEG

«V

me

If, for

and I

any reason this has not been
you a personal check.

will send

received. notify

Sincerely yours,
Fink, M.0.
Professor of Psychiatry
Max

Mi:kp

.

.

IV‘V-W

.
0
1

«any;

77.3w:

mﬂwvzm

�</text>
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                    <text>April 16. 1969
Dr. William Tabor

A. H. Robins and Compamy
1407 Cummings Road

Richmond. Virginia
Dear

Bill,
I look forward

to having

Would you meet me

floor at 10:00

a.m2

you

visit

on Wednesday. April 30.

at Metropolitan Hospital

on

Sincerely yours.
Fink. M.D.
Professor of Psychiatry

Max

MF:kp

~
-

—

.

war-wuur

u-

W:w)nrp-*F'V.WY‘

the 15th

�</text>
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                    <text>Rn" wwuvr- '7‘

»

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«v. .m‘m—w.r—--«m\-r\nwb’aﬁww- .n. ”Upwwvw“w, .,Wﬂ_‘, ~w—r,..1.— . w—nq- ~:-I-*'\
,

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"I'F'1'3"“ﬂr‘mwwltm'ﬂVﬂﬂ-‘m'r—vmvm

April 16, 1969
Dr. Kenneth Lifshitz
Rockiand State Hospitai
Orangeburg. New York 10962
‘vr

to".

17..

Dear Ken.
Thank you

"“1WW-vﬂmrvmwwrwvyn

for your inquiry regarding our paper for

the Society of Biologicai Psychiatry. I had hoped to
present some information from our peotothai data but these
analyses have been more protracted than anticipated. Last
month I withdrew the report.

-v;—.v-v

A

soon as our present studies are compieted I
be glad to send you a copy.
As

Sincereiy yours.
Fink. M.D.
Professor of Psychiatry

Max

MF:kp

nil]

�</text>
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                    <text>.—

«v

m».— ~» '1"~"N-z-~

wo-‘mv-

-.—.~r.

u‘vxmvy-‘n—nvmww mum:

mﬁll!wmrv'm‘wrwmwryrru"‘va-

April 11.
Dr. Philip A. Boyer,

...,.,v_...,,—

w

,

,

__.._.-.v....r.xc. ”an--.”

1969

Jr.

Medical Birector
Marion Laboratories. Inc.
10236 Bunker Ridge Road
Kansas City, Missouri 64137
Dear Dr. Boyer:
Thank you for your letter of April 8, inviting me to
you at the APA. I regret that I will not be attending
the APA meetings since I have a prior commitment outside the
country. I will be at the Society for Biological Psychiatry
meetings and will be pleased to meet with you on Saturday.
I will be at the Hilton Plaza Hotel.

visit

v.

.
V.

.
,

.

.,—.

a
A

.7.~.-...vv

We have begun our open EEG study this week and we hope to
have some data by the end of the month.

”nu—m.

Sincerely yours.

..

“.1,"

Fink, M.D.
Professor of Psychiatry

Max

,,,'.‘....

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"rem.

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“TV——

�</text>
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                    <text>April 11,
Dr. Gert

1969

J. Schulier

Assistant Ciinica] Research Director
The Squibb Institute for Medical Research
New

Brunswick, new Jersey 08903

Dear Dr. SchuIIer:

manuscript has been submitted to Dr. AIain Sanseigne
of Squibb International to be published as part of a volume
commemorating the meeting in Sitges. I have no other information
at the present time.
The

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

A

M,

a.“

o
—

.:
.w
..
.
‘

'"W'"I&amp;'W""nr‘u

�</text>
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                    <text>April 11, 1969
Dr. Marshall Gates
Department of Chemistry
The University of Rochester
College of Arts and Science
River Campus Station

Rochester,

New

York 14627

Dear Dr. Gates:
In checking through my files I find a letter of one year
ago regarding your work with the trans isomer of cyclorphan.

still

interested in undertaking clinical studies with
narcotic antagonists and I am writing to inquire whetner the
animal screening has-come along sufficiently to permit such
trials in the near future.

.Ne

are

Good

luck in your studies.

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>April 10. 1969

Sr. Philip A. Boyer
Marion Laboratories

10236 Bunker Ridge Road

Kansas

City. Missouri

64137

Hear Dr. Boyer:

In checking the supply of pyrovalerone, I do not
find any ”placebo“ tablets. Even in the pilot study
it would be useful to have 20 placebo tablets each for

the

tablets of pyrovalerone.

40 and 20 mg

Thank you.
5

Sincerely yours.
Fink. M.D.
Professorcf Psychiatry

Max

MF:kp

�</text>
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”lawn-Wm

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Dr. Norman

Pitts

Chas. Pfizer 8 Co.
Groton. Connecticut
Dear Dr.

Pitts:
called to see

a patient who had obtained
from
a suppIy of doxepin
a “friend“ and had taken, at a
maximum 50 tablets. She recovered, but I feel that a summary
of this experience shouid be made a matter of your records.
In January we

Sincere1y yours.

.

,

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Fink, M.D.
Professor of Psychiatry

Max
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                    <text>....

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April 10, 1969
m...”

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or

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1.

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Dr. E. G.

Caille

Maitre de Recherches
du Service de Santa des Armees
Chef du Centre d'Etudes et de Recherche:
du Service de Psychologie Appliquae
de

la

Marine

Araenal

Dear Dr.

~

Toulon, France

Caille:

Thank you

for your letter of April 4. addressed to

Drs. Shapiro, Ruchkin and myself.

Dr. Shapiro and I are pleased to accept your invitation
and will make arrangements to participate during the week of
June 15-21. 1969, in Toulon. I would appreciate any information
regarding accommodations. It is probable that we will be arriving
in Toulon on June 15 from Paris.
While Dr. Ruchkin is a member of this Department. his
program is part of a different division and he will write
to you rcgarding his participation separately.
I look forward

my

to meeting

you in Toulon.

My

best regards.

Sincerely yours.

“(-71"

Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>April 10.
Dr. Reginald

a. Eickfnrd

University of California.

1969

San Bingo.

School of undicino
oopartment of neurosciences

La

Jolla. California

92037

Dear Reg.

ﬂesnite much effort on my part. we have been unable to
provide the support noccssary for the exhibition in San Diego.
I regret that we will not be able to demonstrate our EEG

analytic

programs

for psychonhnrmacology.

I

trust this will

not affect the other demonstrations on the 1800. However, since
the New York office of 18M and our sales representative
(Dr. Wayne Jostrand) is making the arrangements for tho equip~
went. I would ask that you advise him of the development.
The

list

of demonstrations is

an impressive one and I

look forward to attending the Congress.

Incidentally.

my

best wishes

on your new

apptintnent.

Sincerely yours.
Fink. M.B.
Professor of Psychiatry

Max

nmp
cc:

ﬁr. Ernst Rodin

�</text>
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                    <text>Aprii 9. 1969
Dr. N. Bohanek.President
Dr. M. Mihovilovic, Secretary

Zagreb. Yugosiavia

Dear Dr. Mihoviiovic,
I regret that I Hi]! not be abie to participate
in the Second Yugoslav Psychopharmacaiogicai Sympasium. ihe program
is quite interesting and i know that I Hi?! be missing much of

interest.

Hay I

trcubie

Thank you
a successful symposium.

you

ta return the registration fee

for your assistance,

and

my

7

best wishes for

Sihcereiy yours.

Fink. M.D.
Professor of Psychiatry

Max

mf/
"
7"

'

"~'

'

w"mmzm‘*'='""v“-""

PW

�</text>
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                    <text>April 7, 1969
Dr. Philip A. Boyer
Marion Laboratories
10236 Bunker R d
a
Kansas City. Misgguriag4137
Dear Dr. Boyer:
I have received the supplies of pyrovalerone and our
trials will begin this week.
As

illness.

initial

subjects will be volunteers without mental
following records are obtained for each subject:

you know. the
The

Summary

psychiatric evaluation. social data

Permit for investigational drug use
Clyde Mood Scale (before and at fixed intervals after drug)
NYMC symptom check list (usually changed for definitive
EEG

experiment)

summary, based on

visual

and

quantitative analyses

pilot study. these data do not necessarily follow a systematic
collection schema. since we are exploring the appropriate times and
dosages for the CNS effects. Nevertheless. the data is available. in
whole or in part. for submission to the FDA. It has been my custom
to invite the monitor to review the data before it is simply duplicated
During a

and shipped.

recent discussion with Dr. Jonathan Cole. now the
Superintendent of Boston State Hospital, he expressed an interest
in studies of vasodilators in the mentally ill aged. eSpecially
In a

wry-«m-

7.:
“n

those with organic mental syndromes. I recollect that you expressed
a similar interest. May I suggest you call Dr. Cole and discuss it
with him. if you are still interested.

i

I

_«

trust that

X

will

have some data within the next 8 weeks.

Sincerely yours.

pvt-«wavy:

an?"

&gt;

'42qu

--

Fink, M.D.
Professor of Psychiatry

Max

pr'ﬂﬁﬁ

MF:kp

�</text>
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                    <text>April 5,

~
._

wwgmwl.‘

ﬂaw-r”

)Qﬁdmrrrm

WJW'TfZwnr,'-&gt;r.’v'.'|fy‘.-7F~,~r

I;
F.

E

E

g
E‘

F

g

i
i
E
E

E

3
5;

1969

Dear Leo,

I have just read your review of the clinical status of
psychotherapeutic drugs in Clinical Pharmncolqu and Tﬂerapeutiua with
great interest and wish to congratulate you on writing an aminently
readabla and useful report. I would apptactate a reprint whan thesa
are available, but will probably gore: the report for the students, since
most of the opiniona are similar to thase which I hava preaaated and
hold.
Taste nra a few cmmmenta that I.would like to ahara
with you. Recently, with regard to the'anti~anxiety druga, um
reviewnd our clinical recordﬁ and found that tha results observed
for chlozdinzapoxide were vary gaod during the early waaks of treatment,
but the response became prograasively less in time. we examined the
data for the possible development of tolerance ané in some reeant cases
we have athieved better results by interrupting treatment at frequent
intervals. In our studiaa of high acne tybamate in tha treatment of
opiate addiction, we were aatonlshed at the rapid rate which the
patients dgveloped tolerance to the aeprasaﬁve an&lt;§sedat1ng effects
of the dosages we uaad ( ti 12 Gms.

)

In the notes on tha traatment of psychosis, why was no
mention made of the possibla utility of long~acc1ng fluphanazine ?
Your choice of thiariduaina as can of the drugs to be
included in one' a armamentariua shows how brave ycu reall.y are, for the
EKG changes which vs found so prominant have haen sufficient t0 deter
me from racommending it for just each purposes.

Again,

my

congratulations on a reviaw well dona.
Sincerely yours,
Max

Fink,

M.D

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                    <text>vApril
Dear

A, 1969

Fritz,

To confirm the sense of our didcnee sue yesterday, I an
taking the liberty of expending the suggestion: ».de for the 1970

progren.~

‘

of unilateral ea“ bilateral electrode place“
may seem to .e a trivial change in the
treatment procedure, but the data are .eet intereeting. The clinical
results for either placement are not similar. but behavioral change
is accoupenied by defined differen» a in memory functions and in
6N8 effects. The oheervatiene eve useful in understanding the relationships between memory function :od outcome; between Chg effect: and memory;
and in supporting theories 0 =he node of action 0f induced convulsions
described more than a deceo ago.

ment

The problem

for convulsive therapy

deny yonng contributors to the field, including
(HY), Blathly (Oregon), White (Ky), Keelhling
(HY)‘ as well as a fine group in the United Kingdom.

There ere
Snell (Indiana), Abra“.
(Ohio), Strain

A
ogrnn dedicated to the contributions of these
authors, with e' interpretation of the observations for our understanding
of the convul. ve therapy process and the treatment of affective
be consistent with the aims of the 1970 meeting. The time
disorders,
such
a review may he at least 4 hours, and perhaps, if
neceeeary :.r
some Engl ~h authors are induced to come. even longer. Such an allocation
of time ran the regular program may be unjustified, and perhaps a useful
solut . may he the holding of a concurrent tension either on the Thursday.
befov: or the Sunday after the APPA.
p

w

,

i

The financial arrangements for these speakers and the
additional expeneee of hotel end publication may be defrayed by Federal
or private granting authorities, since the subject has not yet been
covered in any national meeting. I have an HIKE contract for the

�4

'

..r.-v-.ar.m~&gt;a_w

w.

”ﬁx

4R

~2-

Freyhan

April 4,

1969

.

,

m,

.

,
_

.ww’vrnurﬂﬁn...

evaluation of unilateral and mnltﬁilo monitored ECT, and I believo
that the agency directors would be sympathetic with such a suggestion.
with the

New

With regard to the hotel arrangements, I am proceeding
York Hilton and plan to go there this week.
my

best regards.
Sincerely yours.
Max

Fink,

M.D.

�</text>
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                    <text>April 3.

1969

Dr. Isadore Samuel Zfass
Chairman, Commercial Exhibits
2502 Monument Avenue
Richmond, Vigginie

Isadore,

Dear

Surely. the computer representatives should be
I would suggest Bigital Equipment Corporation.
make the PDP series of computers, Scientific Data Systems
may be interested in getting into this field, and 13%.

represented.

who
who

It

may

be too

late for

many

of these companies. but

perhaps something can be done by phone.

the

My
DEC

interaction has been with IBM only and I do not know
or $85 representatives. Since both instruments are

probably represented

at the Brain Research Institute, perhaps

a member of the organization committee could make the initial
representation. I will be glad to call IBMVand make inquiries

here.

availability of the exhibit hall
at the earliest, I am concerned that this
will make the demonstration very difficult. I will inquire
of IBM as to the feasibility of this schedule and let you know.
with regard to the

on September 12

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                    <text>n,»

«r

m.”

-

ngvr—

Aprll 3,

«m—

'r

2969

1—"

...&lt;.

.rv—w.

Dr. Norman Pitts
Chas. Pfizer &amp; Co.
Grotan Connecticut
Dear Norman.

Please send

parenteral

me

Doxepin

an additional 15 ampules of 2

to continue our

EEG

studies.

mg

Thank you!

Sincerely yours.
Fink. %.0.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>April 3, 1969

Passport Office

U. S.

630 5th Avenue (50th
New York, New York

&amp;

515t

Sts.)

Gentlemen:

bearer, Ira Snapper, is authorized to request
validation of passport #6177566, MaximiIian Fink, M.D..
i request revaiidation to fac111tate a visit to Prague
The

n May.

Sincere1y yours,
Maximiiian Fink, M.D.
Professor of Psychiatry
MF:kp

�</text>
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WK -~-rv*m-

r u-‘w-‘o-w

nm-wu—warwm. '&gt;ZW'-rmﬁ‘wwnxe-y\.wnv

w

..

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April 2.

or.

.

.1:

....,,...,

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1969

Z. Votava

Institute of

Pharmacology
Medical Faculty of Hygiene

Charles University
Praha 10 ~ Vinohrady.
Srobarovo 50, Czechoslovakia
Dear Dr. Votavo:
Thank you very much for your kind invitation to participate
in the Program Committoo meetings on May 6 and 7. in Prague.
I am pleased to accept your invitation and plan to arrive
directly from new York on Monday, Hay 5, from Frankfurt on
196. This is scheduled to arrive in Prague at
tgfgansa
: 0 am.

to working with you
extend kindest greetings from Professor
I look forward

who

are

now

in

new York.

and I oodso pleased to
Roubicok and Dr. Volavka

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

m.-

v.

vn

MF:kp

(Ur-w

:‘pmw-vw

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_i'l“u(r_4

,
,

FWW.

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MSW

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,

�</text>
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‘

~'

V‘

"h“*?"'--w~'wwm-r xv- “w nmw ”(Hyman-owlﬂw

vnﬁm-w...‘m.. WW.
«

»

-

1

-

7-. «&lt;—
-

~
-- K'u‘
7—-m

‘--' ..~.~a~.-~.,.,A.~.._;

W.“ vow—”(9..."5

April 2. 1969
Miss Carol Lindeman

Albert Einstein College of Medicine
Yeshiva University
Eastchester Road and Morris Park Ave.
Bronx,

New

York 10461

Dear Miss Lindeman:
Dr. Abrams and Dr. ﬂornbush were kind enough to bring
Some years ago
this interesting protocol to my attention. which
we compared
in
I was involved in a similar unnertaking
A
Indoklon.
and
convulsive therapy and electrical means
information.
copy of that report is enclosed for your
ﬂood luck

in your studies.
Sincerely yours,
Fink. £4.13.
Professor of Psychiatry

Max

Mszp

”n...“

4"

m,

L.

l
V

-u-vﬂv.

..
..‘

&lt;..,._,_

l.

m.

I».

'In-"mvjn’wv:

=-:y

�</text>
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                    <text>April 2,

1969

Mr. Arnold Canter
P. 0. Box 325
Purchase, New York

Dear Arnold,
In the previous quarter and in this quarter we have
completed this form as enclosed. I believe we are interpreting
the law correctly, but I need your assurance.

Is

this correct?
Sincereiy yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>“v."

.

W":

,

1“—

April 2.

1969

Miss Carol Lindeman

Albert Einstein College of Medicine
Yeshiva University

Road and Morris Park Ave.
York 10461

Eastchestar

Bronx,

New

Dear Miss Lindeman:

Dr. Abrams and Dr. Dornbush were kind enough to bring

Some years ago
this interesting protocol to my attention. which
we compared
I was involved in a similar undertaking in
A
Indoklon.
and
means
and
electrical
convulsive therapy
capy of that report is enclosed for your information.

Good luck

in your studies.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>April 1,1969
Hr. Morris B. Square

Administrator
Forest Hospital

555 Wilson Lane
Des

Plaines, Illinois

60016

Dear Mr. Squire:
With regard to your inquiry regarding my participation in
the PSearch For Mental Health" I regret that I~will not be at
the APA this year. I will, however, be at the meetings for the
Society of Biological Psychiatry and could make time available
on Saturday. May 3. I will be staying at the Hilton Plaza.

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

4

'-7

4

HF:kp

«.7

.
\JH‘“

�</text>
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                    <text>.

' w. ' -.s*"

w wwazxr

WW

,~

nun-4

-~

w .vr— -~w

. m «or,m

swamW.wlva slun-

w

uran- nmv :ux;

-~

w-wn-wam-wauu- .m w '

m w «an YJW-w-www“w

w:- "van-Art‘mwtqn‘nvs'mnwz

A

VA

c.

V

.
.
A

A

.AV

A

A,

,
A.

.

.
.

w

.v

_.

...,.,~

..

April 1, 1969

'a—unwnv&lt;v.rnn'.v&lt;u"

,
.v

,.,,,V,,,,.....vwn..w.—

Hrs. JoAnn Hammell

Scottsdale Jr.

Women's Club

8632 East Keim Drive

Scottsdale, Arizona

Dear Hrs . Howell:

In reply to your inquiry for information to support
your newly implemented "Dope Stop" program, I am pleased to
enclose reprints of some of our recent work. These will
indicate that a useful approach in the treatment of opiate
addiction is the pharmacological antagonist model. Good
luck in your new venture.

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>i-nw

war—”v:

v“

v»

—-—v-.—

April 1. 1969

8. Squire
Administrator
Forest Hospital

Mr. Morris

555 Wilson Lane
Des Plaines. Illinois 60016

Dear

ﬁr. Squire:

With regard to your inquiry regarding my participation in
the ”Search For Mental Health" I regret that I will not be at
the APA this year. I will. however. be at the meetings for the
Society of Biological Psychiatry and could make time available
on Saturday, May 3. I will be staying at the Hilton Plaza.

Sincerely yours,

-—;—v-m.-.~rwr-u~r;vv~ww

.--—-w

Fink, M.D.
Professor of Psychiatry

Max

Wm

W

MF:kp

�</text>
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                    <text>W‘W'w :amuu-r...

:rua—‘amwi-‘w—

.
‘n‘r‘s,, V'v;~5~KVF-:"’k~vrv'~'

WV
,

um,
,

..

,

, m—
I~
.

,

-

i

(m’wm-slvw‘v.
,

m-

.7

*‘v;

,

,,

m"

W"

new.-

n

“A

"Faun.“

'1!va

—

April 1. 1969

E

E

1

E

;

E

Elsevier Publishing

Company

P. 0. Box 211
Jan van Galenstraat 335
Amsterdam, The Netherlands
Gentlemen:

s

E

are sending you a purchase order for a
EEG Journal for 1969.
We are interested
in obtaining issues of previous years for our laboratory.
Will you please advise us as to which years are still available
and at what cost?
Separately

we

subscription to the

E

g

;

Sincerely yours,

;

Mex

Fink, m.o.
Professor of Psychiatry

g

E

E

g
E

i
E,

,&lt;nw-ww&lt;:

War-'1‘.

wax

.w

r.

*‘Nzwn‘rwr

rm

mu-

“(Iran

in
“N'—

"

:.v-—w—v~,mwrrmw~wmr1ww

74'“

unwary-m

MF:kp

.murwn—sxra-v—vvy

'w-V

W'nw'r :WL

�</text>
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                    <text>April 1,

1969

Dr. Ellsworth Cook

ASPET

Bethesda. Maryland
Dear Dr. Cook,

I have read your announcumant at a wbrkahop on Principles
of Drug Evaluation in Man, scheduled for Jun: I~13. I have been
interested in the problem for many years, and have focussed on the
use of electrophyniologta tachniquea in studio: of new drugs in man.
If at :11 practicable, I vauld lika to participata in this workshop;
and am writing to raquest ppplication forms and ptogram.
Thank you.

Sincerely yours,

ﬂax Fink, K.D.

Profasaor of Paychiatry
mf/

�</text>
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                    <text>March 31. 1969
Dr. Tatum E. 1:11
5600 Araanal Street

It.

Lapin, Missouri

Bear Turtn,
Some weeks ago, w1111a3.2uag was in New York and
I issued 13:: year fer him to visit and review
an
invitation
accepted
our computer analytic programs at the alaepvxﬁs. He did so, by checking
the playback at one of ab: records we had analyzed using the pregram
from St. Louis. modified for the IBM 1800 and with the Klinganbarg

revised standards.

‘

His summary is submitted as three figures and
copien of which at: unclosed.
Agreement

in stages a,

a matknd discrepancy in stage:

C

A, and

and E.

D

tablet.

1. good; but there is

Please review those figures and on your next trip East,
can go over tho original data as Bill lung did and assess
perhaps
the bases for the differences in the classifications.
we

Hy

best regards.
sincoraly yours,
Max

cc: Bill lung

Fink, M.D.

�</text>
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                    <text>IMARCH

31, 1969

VEDA ELECTRONICS
2115 DE LA CRUZ BOULEVARD
SANTA CLARA 95050
GENTLEMEN:

NE NOULD APPRECIATE RECEIVING A CATALOG OF THE
PRODUCTS WHICH PERMIT THE REMOTE CONTROL OF TAPE RECORDER EQUIPMENT,
As MAY BE USED IN RECORDING PSYCHIATRIC-INTERACTIONS. NE ARE INTERESTED
IN THE APPLICATIONS SEEN AT THE LANGLEY PORTER CLINIC, IN THE RECORDING

OF NURSING~PATIENT DISCUSSIONS.
THANK YOU.

SINCERELY YOURS,

MAX
'

MF/

FINK, M.D.

PROFESSOR OF PSYCHIATRY

�</text>
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s
E

w'zwrﬁ‘w-v—v"

.-

y-u—‘W‘me

y

March 31. 1969

Dr. Jean Bobon

Clinique Psychiatrlque
Rue

Saint—Laurent. 58

Liege, Belgium

Dear Dr. Bobon:

w",

"m.

W7

I look forward to participating in the Interdisciplinary
I am writing to confirm my planned
Heek on Neuroleptics at Liege.
at l435, SH 794.
arrival in Brussels on Sunday, May

ll,

I look forward

37...”...

to the meeting.

mm”

Sincerely yours,
Fink. M.D.
Professor of PsyCh‘atry

_Max

Hszp

�</text>
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                    <text>V...

.,

W. 7..-..7 .wW—m.-v—- --*

rv1yw'IrwnwmnV w‘mvwwwrm

March

31.

1969

Dr. Allen E. Hussar

Chief, Medical Service and
Associate Chief of Staff for Research
Veterans Administration
Franklin Delano Roosevelt Hospital
Montrose,

New

York 10548

Dear Dr. Hussar:
Thank you for your suggestion of studies of dextroamphetamine
in schizophrenic patients, and the reprint of your work. The
suggestion is very good and should be followed.
Our own program of study is focussed on the effects of
drugs on the waking EEG. This permits me and my associates
to have a more "normal“ family life. There are many workers
interested in the effects of drugs on the sleep EEG and these
include Feinberg in New York, Kales at UCLA and Itil in

Missouri.

an ongoing

I am

sure there are others, but

file of sleep studies.

Thank you very much

I do

not keep

for your interest.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>April 1. 1969

Irs.

JoAnn Hammell
Women's Club
8632 East Keim Drive

Scottsdale Jr.

Scottsdale, Arizona

Dear Mrs. Hammellz»

In reply to your inquiry for information to support

your newly implemented "Dope Stop” program, I am pleased to
enclose reprints of some of our recent work. These will
indicate that a useful approach in the treatment of opiate
addiction is the pharmacological antagonist model.
luck in your new venture.

Good

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>_..

m.“ ..

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p,~

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W.

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--

~
.

March

,

,

31,

.

~,

c.

.0“?

V

,,~3va »-v--

”v .vawwg

1969

Dr. Dean J. Clyde
Clyde Computing Service
Box 166, Coconut Grove
Miami, Florida 33133
Dear Sean,

It was a pleasure to talk about our common interests. I
discussed the laboratory data form, its output and statistics
with Don. He is still not ready to release the programs, since
they require documentation. He also are dissatisfied with the
format of our outputs, including the statistics and are continuing
to work on them. As soon as they fulfill our present expectations,
I would

like to send

for your critique.
service to industry is

you samples

Your idea of providing a
admirable one. Good luck!

.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Hex

“7”,.

.
v;
A
m.

vwvnnmnrwpy—n,

WWI-mOm'lﬂz'rrrnw-qn

,,
&gt;4

"WV-(Wlwllﬂvfywwm

n'v’w'

14“-

MF:kp

an

.awwnm‘-

aw... I597:

�</text>
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                    <text>mevrn~

vvw-

unusu—

Marco 31. 1969
Mr. T. Bloomer~
.

“
i

“—1,

v

.7

"um“

v.1;

n

“gun.

.mv

‘q‘l-«Iw

IBM

‘

475 Northern Bivd.
Great Neck. New York

Dear Mr. Bioomer:

discussed with you on Tuesday, we have been dis»
amount of time that our IBM 1800 has been
vdown.
In comparison with our previous experience with IBM
equipment and in view of the reputation of this instrument,
I wouid appreciate your review of the stabiiity of our equipment
and the program for updating and the probiems in software
support.
As I

satisfied with the

Thank you

mumvrmr-

,qn.

for your cooperation.
Sincerely yours;

“ﬂu—r..-

ﬂax Fink, H.D.

Professor of Psychiatry

MF

:kp

�</text>
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w‘ w‘

March

31,

1969

Dr. Jack Mendelsohn

Alcoholic Research Center
National Institutes of Mental Health
5454 wisconsin
Chevy Chase. Maryland

Dear Dr. Mendelsohn:

J. Miller, President of Killer Pharmacal Co..
visited our laboratories this week to discuss the possibility
of improving the dysfunction of chronic alcoholism by dietary
substances containing trace minerals.
Dr. John

A

your

copy of

files.

his interesting point of

View

is enclosed for

Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max

MF:kp

'

.

�</text>
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                    <text>.7

...

.,.....A,,‘.-_._.,,,_

A".-.

.i
.

~......

March 26, 1969

Dr. Milton Kletzkin
Department of Pharmacology

Wallace Laboratories
Cranbury, New Jersey
Dear

Milt.

I want to thank you for the opportunity to visit your
laboratories which are most impressive.
—

A

.,

"wt-r"

V”.

Sunday I met the Chairman of the 1970 CINP program
committee and discussed the interest in a program of animal
EEG models in psychoactive drug evaluation and classification.
The suggestion was well received, and I would like to discuss it
On

with the full committee

on May

6-7.

If you are interested in participating,.would you be able
to review the world scene and recommend scientists from industry
and the academic scene, who may be able to contribute?
Many

thanks.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>Fr“ wmpvn—u, VwV—w.m—.qymmmm

~-,w—-v—x-w.

w—w».

.n m

wmmmm-

'

~

-

--

-~

e-

W.“ﬂ’ir'vz’vw—"F"('w=~wnwﬂwﬁ‘v~mﬂw'v—

.

March 26, 1969

i

Dr. Maxwell Gordon
Smith Kline a French Laboratories
1500 Spring Garden Street

Philadelphia. Pennsylvania

19101

Dear Dr. Gordon:
L

3

5

3
E

pleased to enclose the most recent reports of EEG
of
measures
psychoactive drug effects. The data is still
I am

and we now have 3 new drug/EEG studies in progress,
one of which is in Phase I Study. He should have more
data by the year-end.

sparse,

Sincerely yours,

l

Fink, N.D.
Professor of Psychiatry

Max

;

w-a,—~yww

-u-r

.‘iFﬁcp

�</text>
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                  <elementText elementTextId="102873">
                    <text>'w"fhmﬂr

“(Ivar-V

"VLW

—-—,—

mu
..
.A.

'lmﬁmr'wm

um-

m.

March

25,

1969

Dr. Burtrum Schiele

Department of Psychiatry
University of Minnesota
Minneapolis. Minnesota
Dear Burt:

is a draft cony of our report as submitted to
Phanmacology and Thenapeuxicb.

Enclosed

Clinicat

Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max

MF:kp

'rw:

‘r-W'W'Ir"ya

�</text>
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v.

-_x-

v

lwyﬁi-V'miw‘h

u-w

vprrw

J-WWWI‘WK'IW‘I‘H

March

25, 1969

Spitzer
Psychiatric Institute
West l68th Street

Dr. Robert L.

The

722
New

York,

Dear Dr.
I am

failed

New

York

Spitzer:

terribly embarrassed that

my

accounting system

me, but during the past few days my secretary
reminded me that we had not obtained the enclosed checks
soon after you lectured here. Please accept these honorariums
on behalf of your participation in our programs and for
the assistance you have given Stanley Feldstein.
My

best regards.

I

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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a-

»

~

~

-

wan»

~

wvw~.v«-.va- .w

March

.-

nwn—wmu

.

-.

~

25, 1969

Dr. Walter Modell. Editor
Pharmacology and Therapeutics
Cornell University Medical College
1300 York Avenue
New York, New York 10021

Clinical

Dear Dr. Modell:
I am pleased to enclose a draft copy of the report
“Clinical Antidepressant Activity of Cyclazocine - A
Narcotic Antagonist" for your consideration for publication
in Clinical Phaamacology and Thenapeuzica. This report
summarizes our experiences with cyclazocine in the treatment
of depresSive illness an application which was suggested
by our studies of its characteristic EEG effects.
—

studies were completed last year but I have
withheld publication pending studies of this compound by
other investigators. Reports of studies by others will
These

be presented at the meetings of the American Society of
Clinical Pharmacology and Chemotherapy.
Thank you

for your consideration.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

enc.

�</text>
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                    <text>March 25, 1969
Mr. Jack M. Rosentha]
Room 13

Sun and Shore Hotel
North Bath Avenue
Long Branch, New Jersey

Dear Mr. Rosentha]:
I regret that we have
studies have just begun.
Thank you

no publications since our

for your inquiry.
Sincerely yours,
Fink, m.
Professor of Psychiatry
Max

MF:kp

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                    <text>l

v.

,
A

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March

‘&lt;._V_V-.,,..&lt;.=.t._-v_....-,

To.

,..,,A

,ﬂm".

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.

25.

1969

Dr. Joseph 6. Bird

Director. Experimental Medicine

Sterling-Winthrop Research Institute
Division of Medical Research
90 Park Avenue (5th floor)
ﬂew

York.

New

York lOOlG

Joe.

Dear

copy of our report as submitted to
and
czinicaz Phaamacozogy
Theaapeutica.

Enclosed is a

draft

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

HF:kp

�</text>
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2

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March 25, l969
Mr. Arthur Werbner
Management Science Advisor

Honeywell, Inc.

Data Processing Division
West Druid Hills Drive North East
Atlanta, Georgia 30329

Electronic

6

Dear Mr. Werbner:
I regret that the reprint you requested is no longer
available. I am taking the liberty of sending you a copy of
another report which describes the application of these
studies and which may be of interest.

If your thesis is directly related to

EEG

analysis,

you to ask more specific questions
it
in relation to the problem and perhaps we can be of some
additional help.
may be useful

for

Sincerely yours.

Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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“an.“ 1...

«pp-FTEYWYVW

:

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v

v

.7

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.

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March 25 , 1969

Dr. Daniel X. Freeman
Professor and Chairman
Department of Psychiatry
University of Chicago School of Medicine
Chicago,

Illinois

Dear Dan,

It is

a pleasure to enclose reprints of our reports in the
edited by Dan Efren, recalling the splendid meeting
of two winters ago. The assignment gave me great pleasure and
has been rewarding in ideas for our continued research effort.
new volume

Recently I met your associate, Jack Green in our
mutual roles as Chairmen of the Computer Committees of our
respective facilities . His novel views of narcotic antagonists
were of special interest. The differences in emphasis between
our Department under Al Freedman and the existing facility

at Mount Sinai became grossly apparent. Dr. Green seems
to be involved in the selection process for a new chairman,
and is less acquainted with the research and comnunity action

programs fostered by Al than would be desirable. In your
discussions, a description of these programs, from your
vantage point, may be nutually useful.
My

best regards .
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

ME’:kp

enc

o

e

,

.

,

“v“.

v

.

,, ....

v,

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�</text>
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                    <text>March

25,

1969

Dr. Burtrum Schiele
Department of Psychiatry
University of Minnesota
Minneapoiis, Minnesota
Dear Burt:
copy of our report as submitted to
and
Phanmacozogy
Thenapeuzicb.

Enclosed

Clinical

is

a

draft

Sincereiy yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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              <elementText elementTextId="37932">
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                    <text>March 25, 1969

Spitzer
Psychiatric Institute
West l68th Street

Dr. Robert L.

The

722
New

York, New York

Dear Dr.

Spitzer:

terribly embarrassed that my accounting system
failed me, but during the past few days my secretary
reminded me that we had not obtained the enclosed checks
soon after you lectured here. Please accept these honorariums
I am

behalf of your participation in our programs and for
the assistance you have given Stanley Feldstein.
on

My

best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                <text>Correspondence to: Spitzer, Robert l.</text>
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              <elementText elementTextId="37938">
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              </elementText>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="37941">
                <text/>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="37942">
                <text>&lt;a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank"&gt;IN COPYRIGHT - EDUCATIONAL USE PERMITTED&lt;/a&gt;</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="37943">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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          </element>
          <element elementId="44">
            <name>Language</name>
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              <elementText elementTextId="77996">
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              <elementText elementTextId="84557">
                <text>application/pdf</text>
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          </element>
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              <elementText elementTextId="91118">
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        <name>Correspondence</name>
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                <name>Text</name>
                <description/>
                <elementTextContainer>
                  <elementText elementTextId="102879">
                    <text>r

wuww. 7:

snw~~wsn-

were,..

«w ..

w,w-

;. .

,

..,ar- 1 :1

wwwu-u-mm-.mauv-WIFVJWVJWT‘xw v.-.:..—w_uw ~wW-W

V

.

25,

»-

... \tw-vyzx'v-wu-rwav‘f«aqua.
~.

awmamvwvw- «-:.~r- w.

1969

Mr. Donald Cheetham

;

:

—x3Juv-

March

E

i

—.

-

Smith Kline a French Laboratories
1500 Spring Garden Street

Philadelphia

l.

Pennsylvania

Dear Don,

Recently I called regardin a search through the Thorazine
literature for mention of comp ications in relation to skin

taking the liberty of enclosing the original
I would appreciate a
similar search for the following terms.

disorders.

letter

I am

from Dr. Guthrie to Dr. Kline.

bullous dermatitis

eczematous dermatitis

E

vescicular dermatitis
dermatitis venenata

?

bullous erythema
bullous multiforme
weeping eruption
oozing eruption

'

g

g

*

photo—allergic dermatitis

%

pphoto-toxic dermatitis

i

with or without

t

vesciculation

eczematization
bullous reaction

E

as a consultant to the State of New York with
regard to a case of this kind and I would appreciate all the
help I can get in presenting a fair statement of the toxicity
I am

acting

ascribed to Thorazine.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

-

.

Wm-» .W.

., .. -7

. .-..

.

r. u 9.

�</text>
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                <elementText elementTextId="1">
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    <itemType itemTypeId="1">
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          <element elementId="50">
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                <text>Correspondence to: Cheetham, Donald</text>
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                <text>1969 </text>
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            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
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            <elementTextContainer>
              <elementText elementTextId="37948">
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          <element elementId="49">
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              <elementText elementTextId="37949">
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            </elementTextContainer>
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          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
            <elementTextContainer>
              <elementText elementTextId="37950">
                <text>The Max Fink Collection</text>
              </elementText>
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          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="37951">
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              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="47">
            <name>Rights</name>
            <description>Information about rights held in and over the resource</description>
            <elementTextContainer>
              <elementText elementTextId="37952">
                <text>&lt;a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank"&gt;IN COPYRIGHT - EDUCATIONAL USE PERMITTED&lt;/a&gt;</text>
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            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="37953">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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          </element>
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            <name>Format</name>
            <description>The file format, physical medium, or dimensions of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="84558">
                <text>application/pdf</text>
              </elementText>
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          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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          </element>
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            <name>Contributor</name>
            <description>An entity responsible for making contributions to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="97680">
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        <name>Correspondence</name>
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  </item>
  <item itemId="3796" public="1" featured="0">
    <fileContainer>
      <file fileId="2254">
        <src>http://exhibits.library.stonybrook.edu/mfp/files/original/3f9066d264d4f96ffe9f5e3ebd73facf.pdf</src>
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                <name>Text</name>
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                <elementTextContainer>
                  <elementText elementTextId="102880">
                    <text>..
a
V

”7...."

Dr. C. Forster

TO:

DATE:

March

25.

1969

‘

Dr.

FROM:

M.

Fink

have supported the appointment of psychiatric assistants
from research funds for more than a year and one-half and I
am writing to ask that you undertake a report to the administration
We

regarding the following:
1.
2.

,,
q.

.

Our

experience in terms of number of aides, assignments

and attendance record .

Training programs offered, and degree of participation,
limitations and handicaps. certification.

3. Medical status and any unusual ex eriences (please
obtain this from the medical staff

..m...,.,w,4.

"1w...

"my-hw—V—v-

patients, staff

4.

Acceptance or lack of acceptance by

5.

Comments regarding changes in social and community
behavior of each of the aides.

6.

Recommendations regarding ultimate funding for
continuation of programs beyond 12/31/69.

7.

Any

‘wrw‘ofw‘n—‘rv-

and/or administration.

.vww'rﬂ'muw

m
w

other

comments

MF:kp

"way-v-

‘-

(avw.w*

may

suggest themselves.

I believe these men have contributed to our programs but an
In view of the restrictions in funding
which I anticipate, I would like to plan that this program be
independent by January 1, 1970.

assessment is necessary.

wrwmwur-

riv

that

cc:

Mr.

I.

B. Schwartz

�</text>
                  </elementText>
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              </element>
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        </elementSetContainer>
      </file>
    </fileContainer>
    <collection collectionId="1">
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Correspondence</text>
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              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
    <itemType itemTypeId="1">
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      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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                    <text>TO:

Dr. C. Forster

FEB-i:

Dr.

DATE:

March

25, 1969

hi. Fin}:

have supported the appointment of psychiatric assistants
from research funds for more than a ye r and one~haif and I
am writing to ask that you undertake a report to the administration
we

'regarding the foiicuing:

experience in tenns of number of aides, assignments

1.

Our

2.

Training programs offered, and degree of participation,
limitations and handicaps, certification.

and attendance record.

‘

3. Medicni status and any unusuai exoerienccs (please
obtain this from the medicai staff}

patients, staff

4.

Acceptance or inch of acceptance by

5.

Consents regarding changes in sociai and community
behaVior of esch of the aises,

6.

Recommendations ‘egarding

7.

and/or administration.

ultimate funding for

continuation of programs’beyond 12/31/69.
Any

other

comments

that

may

suggest themseives.

beiieve these men have contributed to our programs but an
assessment is necessary. In view of the restrictions in funding
which I anticipate, I wonid like to pian that this program be' .,
c'f€:*
independent by January 1, 1970.,
I

.

J

_

HF:kp

cc:

Mr.

I.

B. Schwartz

�</text>
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                    <text>Hard) 2Q, 1969

'

Dr. T. A. Ban
Douglas Hospital
6875 LaSalle Blvd.
Verdun, Quebec
Canada

Dear Dr. Ban:

I

that you have canpleted a pmlimirm'y
in
the
of depression. You know
of
cyclazocine
survey
we am particulwly interested in this application, and I an
have recently heard

Want

writingtoask foracowofyom‘pmliminaxympwt,vmenthatmy
beoane available.
Many

thanks and

my

best-regards.
Sincerely yams ,

cu...

ma,“

_

,_.

Fwy—VF-

Max
WWWVv.Ww-.—W.

w:

m

Fink,

M.D.

Professw of Psychiatry
MF:kp

�</text>
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                    <text>w...“

March 2“, 1969

Dr. Allen Raskin
National Institutes of Mental Health
514514

Wisconsin
(base, Marylmd

Chevy

Dear

Ir.

Raskin:

have recently completed our report of the trials
of cyclazocine as an antidepressant. I am writing to
aakifmytrialsbygmpe ctherﬁxmAbuzzambaMSchiele
have been reported, and if so, if the data is available.
We

Many

thanks.

Simly
Max

rink;

yams,
M.D.

Professor of Psychiatry

MF:kp

,

WWW-aw

w" m,wvva

Viv-w,-.

a?

�</text>
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                    <text>March 2a, 1959
11‘. O.

Vinar

The George Washington lkxiversity

Blane-trio Laboratory

11% Ninetemth St. , NM.
Washington, D.C. 20036

Dear Dr. Vinar':
The reprint you requested is enclosed. It was a
pleasure tometyouandyommwife inthia coxmtryand

I lod&lt;fomwardtoworkingwithyminthe CINPprogram.
My

best regards.
Sincerely yours ,
PM

PM,

MOD.

Profwa of Psychiatry

�</text>
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                    <text>March 2a, 1969

Dr. Burt Schiele
Department of Psychiatry
University of Minnesota
Mixmeapolis, l‘ﬁnnesota
Dear Burt,

I have just received the

1969 program

of the

American

announcing the
Society of Clinical Pharmacology and Chamﬂmerapy
know
we are
You
report of cyclazocine as an antidepressant.
read a copy
to
Is
possible
data.
very much interested in your

it

of the data tables?
Many

thanks.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>March 2a, 1969

Dr. mar-1. Dewan, Ph.D.
Redford Air Form Base

Massachusetts

Dear Dr. Dewan,
have read the abstract of your presentation at the
EEG: by conputeﬂ
,
with great interest . If a oopyoof the report may become available ,
my associates and I would appmciate the opportunity to mad it.
We

latest sleep mting, 'Nonlinaar analysis of the
Thank you

for your cmpemtim.
Sincerely yours ,

Max

Pink,

M.D.

�</text>
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                    <text>March

214

,

1969

Captain Lessmrd

Brnoka Air- Pome Base

Texas

Dear Captain Lenard,
have read your abatmct, "Studies of Ran-Crossing
Information of Sleep Em" with great interest. If a copy of the
report may became available, my ammciatas and I would appreciate
We

the:

opportmity to read
Many

it

in detail.

thanks .
Sincemly

Max

Fink,

yum ,

£4.13.

meaeaor of Psychiatry

�</text>
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                    <text>t

March 20. 1969

Dr.

Irvine Page, Editor

Modern Medicine
4015 N. 65th Street

Minneapolis, Minnesota 55435

A“-

Dear Dr. Page:
sew-,mvwniww

.-~‘n...~

-&lt;-‘—"ur‘r."n.

Your

editorial, "Further Evidence on Methadone and Criminal
is commendable in its recognition of the contributions

Addicts"
of Drs. Dole and Nyswander to the treatment of this problem.

Further data now available, and not included in your summary,
support your recognition.
Dr. Dole has reported in the successful teaatment of a
group of involuntary. incarcerated criminal addicts - a group
heretofore considered completely untreatable. (Presented at
the MAS-NRC meeting in Palo Alto, February l968).
In our independent study of opiate antagonists, we have
used methadone maintenance as our "standard” treatment. The

treatment is highly successful with a negligible drop-out rate.
Expansion of this program has been limited only by our desire
to continue our exploration of alternate treatment models,
notably cyclazocine and aaloxone. and not by any difficulties
with the methadone treatment program.

interested in knowing that Dr. Efren
Ramirez has left his post for reasons that are undefined,
described unofficially as disenchantment with the results of
Finally,

you

will

be

his program.

Your support of Drs. Dole and Nyswander

commended.

is

welcome and

Sincerely yours.
Fink, M.D.
Professor of Psychiatry
Max

MF:kp

Enc.

�</text>
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                    <text>March

l7,

1969

Dr. Jerome Levine

Psychopharmacology Research Branch
National Institute of Mental Health
_5454 Wisconsin Avenue
Chevy Chase, Maryland
Dear

Jerry,
Thank you

of award of

MH

for your efforts

13358-03 arrived

behalf. The letter
this afternoon.

on our

it

is probable that the delay was occasioned
the administrative practices of this institution. 1
As

have already informed our Dean of the

trust

that the

Your

same problems

difficulties,

will not recur.

assistance iS-appreciated.
Sincerely yours,
Fink, M.B.
Professor of Psychiatry

Max

MF:kp

by

and,

�</text>
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              <elementText elementTextId="38053">
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                  <elementText elementTextId="105743">
                    <text>NB... “Tami/r».

r" ..

..-=-,..~

...,.,,,,....,

31T.,._w,rr.l "Weary...”w

March

my?

V

l..

,

.... p,“ mew—WT

~

V,

_.

,

V."

a

.,. m. .... .,

l4, i969

Dr. Jack Pefer Green
Chairman, Departmenf of Pharmacology
Mi. Sinai School of Medicine

New

York,

New

York

Dear Dr. Green:
Bofh Dr. Shapiro and

very much enjoyed our meeting
Perhaps There will be programs of common inferesf
hope fhaf we can work fogefher when necessary.
i

wifh you.
and

i

am enclosing some of The most recent reprinis from fhis
iaborafory. if fhe problem of anficholinergic drugs is of
i

parflcular inferesf, may recommend Volume 28 of
(in Bluuln Ruecvwh, Antichou'nugic iiawanogem,
i

Pnognebb
which i

edifed wifh Dr. Bradley. This volume contains addlfional
reporfs espetcaiiy focussed on this sfarfiing group of
hailuclnogens.
i

will be pleased

a? your convenience.

To show you Through our

iaboraforles

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychlalry

MF:kp

,g or

�</text>
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                    <text>wmtwwvn-

.nvvm-m-m‘

.wvn.

March

Dr. Karl

M.

l3,.l969

AlJian

Department of Medical Services

A. H. Robins Company
l407 Cummings Drive-

‘

Richmond, Virginia 23220

Dear Dr. AiJian:
i
i

have

must apologize

Just returned

‘to find your

letter.

for not having

answered you sooner but
from a vacation and professional meetings

to your question of ophthalmologic studies on
chronic butaporazine patients, l regret that systematic
ophthalmologic studies were not done before or aftér butaperazine
therapy.
With regard

‘

in reviewing the subjective complaints and symptoms of

our patients

who

have received or

are receiving butaperazine,

blurring of vision was a complaint of one patient and this
,improved aftor reduction of dosage. My associate recalls two
other instances of blurring of vision which was transient without
3
change of treatment.
‘

Despite specific inquiry,
ocular symptoms or signs.‘

my

associates recall

no

other

there are four patients receiving
butaperazine for periods exceeding one month. if it would
be of some merit to have you examine these patients, i am
sure we can arrange this.
At the present time

Thank you

for your inquiry.
Sincerely yours,

vamp-van:

1,.)

Max Fink, M.D.
Professor of Psychiatry

Mszp

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                    <text>March

l3, I969

Dr. Jona‘l’han 0. Cole

Superlnfendanf
Stale Hospllal

Bosfon

Bosfon, Massachuseffs 02l24
Dear Jonathan,
The speclflcaflon of magnellc tape system described by
Ernesl Harfmann ls compaflble wlfh our SP-SOO, for recordlngs
made a? 7 l/2, 3 3/4 and l 7/8 Inches per second recordlng

speed. These speeds are Idenflcal fo fhose available to us.

3

The maJorlfy of our lapes are recorded a?

3/4 lps.

lee

Ernesf

my

l

7/8 and

has? regards.

Slnceraly yours,
Max Flnk, M.D.
Professor of Psychiatry

Mkap

�</text>
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              <elementText elementTextId="38082">
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              <elementText elementTextId="38083">
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                <description/>
                <elementTextContainer>
                  <elementText elementTextId="102889">
                    <text>,

—_

“.77... m:

.

,N—

n-

,

nun-m7. y

‘

7m“... "w.

“‘

WWW -lnnanpwuwwqua—warm

March
Mr.

Porlo

New

York,

Chief U. S. Chemisf
64| Washingfon Sireef,

|

New

York

Room

.

’17-“

-

W‘s—w

~_-

~

..

”ﬂung—w...

l3, i969

l003

Dear Mr. Porlo:

Following my discussion wllh Mr. Tagley of The
Federal Bureau of Narcotics, i am enclosing +wo samples
of presumed narcotic subsfances confiscaled from paiienls
admiffed to our deparfmenf during The pasf monfh. i
would appreclale an analysis for oplaTe subsfances (heroin).
We have been Told ihaT lhe malarial may haVe been cu? wifh

procaine.

Sample

capsule.

3/l is

in

silver foil; sample 3/8 is

in whife

Sincerely yours,
Fink, M.D.
Professor of Psychlalry

Max

Mszp

�</text>
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                  <elementText elementTextId="102890">
                    <text>m.v""“"'lVVW:M‘I—V

2mm”

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i

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43‘".

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,

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Max saw.”
v.

or

F‘upn‘“mn,y rum-aw.-r*-.-w-v.-.1-—vv~...r.-._-lv.,

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March I3, l969

"Ana..."

-

n...

Imam...“

M4,.

i...

Mrs. Tess Lindgren
CounTy of Los Angeles i969 Grand Jury
_

548 Hall of JusTica
Los

Angeles, California 900l2

Wasp-"MW-

«hum-u—

sm’g‘rvv

v

Dear Mrs. Lindgren
Thank you for your leTTer of February 5. Our sTudies of
marijuana began in November l968 and we have no conclusions
or daTa which have been published. One suggesTlon ThaT we do
have for a group of clleens like yoUrself comes from our

personal experience.

became inTeresTed in marijuana research in
lT Took us more Than i8 monThs To obTaln The
May I967.
The facT ThaT
supplies Through legal channe s - This despiTe
New
York.
marijuana is indigenous To The sTreeTs of
research
To
make
The
ThaT
encourage
clTizens
can
efforT
Any
raTher Than placing obsTacles in lTs paTh would be commendable.
We

flrsT

,n,

Sincerely yours,

,...,_x

m

“to

Max

1"WW'I-mm-n-n-v

mm-m'wwh

'h-N-vv‘r'v‘n,

v

‘,

“Wm-am":

‘r/vvvrm‘r‘i

Fink,

M.D.

Professor of PsychiaTry

wwwmawmwm-"im—

MF:kp

TV.

v

w.” w.

,

�</text>
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                    <text>r‘

WWW-r

WW

—:r.--&gt;- -»

- ”-rv‘r'ni-‘Il'rv'

«u

T'w-va-rmx‘y,

.,

..

‘__

_.‘..

,N, ,.

,

March l3, l969

Dr. Hudgon Hoagiand
222 Maple Avenue
Shrewsbury, MassachuseTTs 0l545
Dear Hudson,
Thank you

The manuscrist abouT sex—raTio and
your commenTs. The daTa are small and

for reading

schizophrenia and for
require furTher duplicaTion and eiaboraTion and we are proceeding
wiTh Two proJecTs - one To repiicaTe The flrsT sTudy and one
To predicT The sex of

picTure.

offspring

based upon The maTernai

clinical

ThaT The preposed hormonal mechanism is speculaTive.
ThaT
The
clinical Trials ciTed in The manuscrist auggesT
However,
The adminisTraTion of TesTosTerone or progesTerone can enhance The
TherapeuTic effecT and decrease The relapse raTe from ECT. Torghele's
successful TesTosTerone-ECT TreaTmenT of chronic, Therapy—reslsTanT
schizophrenic women furTher suggesTs ThaT These hormones may
affecT The psychoTic process.
I

agree

difference in produchon of TesTosTerone and progesTerone
and female feTuses ls a crucial quesTion. WheTher
male
beTween
The difference ls in amounTs or in funchonal achvlTy of feTal
TesTosTerone or in The feTal meTabolism of placenTal progesTins
To androgenic forms is noT yeT known, buT such a difference
would indeed sTrengThen The argumenT. The possibiilTy ThaT These
hormones may affecT The chromosonal DNA codons in The defecTive
parTiculariy inTeresTing,
offspring (all defecTs were in The CNS) isinTellecTuai
funcTion
of
increased
DalTon's
reporTs
in View of
of
progesTins
dosages
received
high
moThers
in children whose
in The early pre-parTum period.
The

The quesTions you

raise should

sTimuIaTe Taylor and Levine

in furTher invesTigaTion and They and l Thank you for your Time
and commenTs. They will be presenTing This daTa aT The SocieTy

of Biological PsychlaTry in
This furTher aT ThaT Time.

May

and

i

look forward To discussing

Sincerely yours,
Max

Fink,

M.D.

Professor of PsychiaTry

Mszp

wwmm,

-

van-'ervv

414.”

�</text>
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              <elementText elementTextId="38112">
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                    <text>March

l3, l969

Dr. Alaln Sanselgne
Squlbb International
909 Thlrd Avenue

New

York, New York l0022

Dear Alaln,

Enclosed ls another report whlch was requested and whlch
should appear In a book edlted by Charles Shagass.

ulsh you would get a publlshar and
Lulgl Buccl would feel fultllled.
l

My

edltor so that

best regards.
Slncerely yours,
Max

Flnk, M.D.

Professor of Psychlatry
Mkap
60C .

�</text>
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                    <text>"‘r

vw

ew—

mvmn—w-«wv;

-rr~v-

mum-

Knvﬂwv

ww.w~v~wwmmrrmv

March

l3, l969

Dr. Charles Shagess
Eesfern Pennsylvania Psychiafric inslifufe

Henry Ave. and Abbotfsford Road

Philadelphia, Pennsylvania l9l29
Charlief

Dear

’

Enclosed are Two Copies of The reporf which you requesfed
”Long~AcTing (Depot) Phenofhiezlnes in Emergency and Mainfenance
Therapy of Psychosis." I believe fhls states The mos? qualified

opinions and is fully consistenT-with our experience and fhe

literature.
i

Trust This us useful.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MF: k5

�</text>
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                  <elementText elementTextId="102894">
                    <text>March

Professor C.

l3, l969

J. eras

Deparfmenf of Biological Chemlsiry
Universily of Alhens School of Medicine

Goudi, Alhens, (609), Greece
Dear Professor Miras:

Since your

lefler of January l0,

i
have had The
*0
number
of
a
people in Washinglon
speak
opporfunlfy
New
and
York regarding a sludy program in marijuana. if
is our infenflon #0 apply To The Public Heailh Service

To

for supporf. There are aspecfs of these sludles Thai
’besf be done in associaflon wilh your laboratories.
For This reason,

i

vislf

would like To

may

wifh you in

i will
be
presenl if is possible
April or May.
in Yugoslavia a? fhe end of April (24-26) and could vlsll
wlfh you lmmedialely lhereaffer.
if i am no? successful

AT

In making fhis frip,
mid-May and would plan
I

+ha+

will definlfeiy be in

to visif wilh

EurOpe in
you aboul May 20.

Are eiTher of lhese periods agreeable?
you as soon as my plans are crysfaliized.

i

will wrlfe

To

are very much lnleresfed in obfaining some addlflonal
and was pleased To read fhaf you now have 2 grams.
Would if be possible lo reserve a+ lease one gram for our
We

THC

use?

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychialry
MF:kp

�</text>
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                  <elementText elementTextId="102895">
                    <text>March

l3, l969

Dr. Jerome Levine
Psychophermacoiogy Research Branch
Naflonal lnslifufes of Menfal Heal+h
5454 Wisconsin
Chevy Chase, Maryland
Dear

Jerry,
Our program MHel3358 (Quantifefive

EEG

Sfudles in

Psycho—

pharmacology) is now in ifs Third year. The annual renewal '
date is January i. As of loday we have no? ye? received The

letter for

award

MH~l3358~03.

have checked carefully within our adminlsfrafion and
have been reassured The? we have complied wlfh all fhe
requirements set forlh by lhe adminisfrafors in Washington.
i

am unable +0 utilize The funds in resfrlcfed calegories
wifhouf lhe leffer of award, would be grafefui if one of
your adminlsfralive asslsfanls could look info This for me.
As

i

I

Many

Thanks.

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychlafry
MF:kp

�</text>
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            <elementTextContainer>
              <elementText elementTextId="38152">
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              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
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                  <elementText elementTextId="102896">
                    <text>w-V'r‘

w‘vy‘. Immnn‘fw'".

WWVNK.A

~

March
Mr. R.

a.

Sfar Roufe

l3, l969

Mannlng

Soufh Plymoufh, New York l3844
Dear Mr. Mannlng:

spoke #0 your wlfe l? was To lndlcafe fhal we have
had dlfflcullles ln obfalnlng supplies of marljuana for research
do
purposes. Whlle l would like very much To have a supply, we know
Thls
already
Perhaps
you
no? have grant funds for
purpose.
fhal The Naflonal lnsllfufe of Menfal Healfh has announced +he
believe
esfabllshmenf of a few growlng confers for marlJuana.
The
To
of
rho
mee?
needs
sclenflsfs.
They wlll affempf
When

I

I

Thank you very much

for yourlnferesf.
Slncerely yours,
Max

Fink,

M.D.

Professor of Psychlalry

MF:kp

�</text>
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                    <text>9:20:

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~S-

eta todﬁ .ytncnded

Yntnom txen
‘

10d5T ~13

ni vines tnemtniodqe noedonul woo beaaim on
edt pnitub todteoot pnittog to daemon: ed?

etuov
'

Y

ieweonia

March

i3, i969

Dr. William R. Tabor
Director, Medical Regeprohpygn x3e

A. H. Robi

sh

.

to ﬁoaaat01q

i407 Cummings Drive
Richmond, Virginia 23220

e#:3M

Ogﬁﬁwgﬂkﬁrsneod tauL asd ybute Devi—HHA edt not lsvonoqﬁ .B.q
nice 25 thee ed biuoda betaengua useWetpdt‘emtot edT
ii)as ‘l‘ybamate
paper on Drug Dependence:
haymgymigyed
the galley proof on the tybamate report from the Joannnﬁ 06
Clinical Phaemacotogy and have ordered 300 reprints for our use.
if Mrs. Corneal would like to order an additional supply, please
have her call my secretary.

(2) Buteperazine Syrum Study: This study has appeared in
Canaan: Thenapauxic Reaennch; however, we have not yet received

reprints.
(3)

AHRleDO: With regard to Mr. Banner and the City of
York with regard to AHR-IQOO, i called him and he was
principally interested in a general statement about AHR-lQDO.
After our discussion he indicated that he would approve this
study. He was surprised by the request from the Commissioner
of Hospitals, indicating that this was the first such request
that he had received in twenty years. We have three patients
on the ward now and we are training our staff using butaperazine
(which is apparently quite successful). l anticipate no further
difficulty in obtaining approval and believe it should be forthcoming shortly.
New

Fenfluramine Exhibit for

APA: i regret to tell you that
called the exhibition manager of the APA he indicated that
we were much too late to apply for space, the deadline having
been January l.
am disappointed and accept the responsibility
for not anticipating this deadline. As thought about the kind
of exhibit i wish to make, it occurred to me that we might try
such a display at the forthcoming international EEG meetings in
San Diego (September l4-20, i969). if it is successful there,
perhaps we would like to use that material for the APA in l970.

(4)

when

i

i

i

�"WWW-1|

W

v—w

or, Tabor'

wva—rw

~2—.

"

'

March 13, I969

.

We mIssed our Innehson appeInfmonf

early In February. Wha1
1he chances of
1ogether
durIng 1he nex? mon1h?
go11Ing
H

are

SIncereI y y ours ‘

eaex .EI 131m
'

1odsT .R mmIIIIW .18
Max Fl ngﬁawgeﬁ IsalbsM 30139110

Professor of

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The forms 1ha13:!en su osfed shauld be193q°5q
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March

,
.,
~

l2, l969

imm-

..

—'wq,w.m

”a.“

It'guvwl'Vm'

mr

Dr. Oidrich Viner
The George Washingfon University

Biomefric Laborafory

ll45 Ninefeenfh Sireef, N.W.,

Room

Washingfon, D.C. 20036

6l8

Dear Dr. Vinar:

Affer

to

yesterday my secrelary reminded me
The defes of the American Psychlefric
Associalion meefings (May 5-9, Miami Beach). These are among fhe
mos? useful meefings of our colleagues.- l fhlnk you would enjoy
affending The meetings and l am sure fhef Dr. Lehmann and ofher
American members of fhe CINP will probably prefer fo effend.
l

spoke

The? May 6 and 7

you

are wifhln

is There still lime To arrange fhe meefing of fhe Program
Commiffee +0 follow The conference on neurolepflcs in Liege?
sure

if necessary,

you

we can forage fhe APA meetings, buf
will agree fhaf affendence at bofh may be more

I

am

profitable.

4"‘v'rvlk

if if is possible for

w

m'r

w

"Winn-I4

you

to visif us,

Roubicek and Dr. Volevka will Join

inferesfing.

me

i

am

sure Professor

in making your

Sincerely yours,

vomA

erw-vmz-zaw

Jun-or

Fink, M.D.
Professor of Psychiatry

Max

Mszp

vlslf

-~

~-

unvr-rr

um

-'- .v

r

w» rv

- ~1wT1r-'-

,

"&gt;—

�</text>
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              <elementText elementTextId="38173">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                    <text>Earth
Dr. {Bert

J.

13., 1969

Sici‘mllex‘

Assistant Clinical Research Bimctor
The. Squibb Institute for Medical Fﬁsam
New Bmmswiok, ﬂew Jersey 08903
Dear Dr. Schuller:
31-15:ka

you

disthinuim

study period.

for your inquiry regarding; the reason for
depot f1uphenazine in 22 patients during a
'

Fifteen {wtienta were disomtinued ltuecause of failmr'e
to keep appointmen‘m; of these, tl‘m'ee were imaznvec} , ten were
unimpmvec‘; and We had complained

of secondami effects .

Eight mtiemts cut of the fifteen haﬁ remix/12d l~~2
injectims mly, and. the regaining seven patients received
34»? injectt'ums.

patients were dischemg cm transfemed to other
fm‘ﬁf‘ﬁeatmnt by the ﬁnerapist; of these, two refused to
continue treatamt, time had secondary effects , mo of which
war»: hmyﬁtalized by other doctors , cm was; heapitalized fem
alcoholism, and another one was hospitalimd became of the
severity of his mmtal ccmditim.
Seven

.3

fmm patients were hospitalized. MG patients
were disomtinued because of toxic effects or physical

In

total,

mlicatims.

Sincemly yours ,
nun-wyww;

mu

.
r.

v

mm’w‘nmJ'l—Ir

Ptofessor of Psychiatry
Mszp

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                    <text>Mann 7, 1959
Dr. Arnold

J.

Mamiell

Departmnt of Psychiatry
Hunm Behavior
Sdmcol of Hedicine

of California,
Wimity
California

Irvine,

and
'

Irvine

Dear Arnold ,

for your letter of Febzuary 21, indicating
two
abstracts for the Society of Biological
of
acceptmoe
am
delighted that two of my young associates
Psychiatry. I
able
be
will
to present their musual work on "Effects of
Thank you

Maternal Schizophrenia on Sex of Offspring."

I am writing, however, to ask if it is possible to withdzm
the papa "Cerebral Reactivity Model in Schiﬂamrenia A Roappraisal". Some of the work whid'x I, had wished to include
has met unexpected difficulties in the analysis and neither
Dr. Itil nor I think that we wand have sufficient mterial
available by the end of May to justify the presentation.
I regret my inconvenience that this my cause you.
Thank you for your indulgence.
-—

Sincerely yours ,
1% PW, MOD.
Professor of Psychiatry
Ifzkp

�</text>
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                    <text>I

l
I
E

P

x
x

March 7 , 1959

Dr. Helen

:3.

Wt

Associate

Kaplan

meesscr of

Psydmiatry

of Psychiatry

New York Medical College
5 East 102m Street
New York, New Yam 10029

Dear Helen,

thoroughly deligl‘lted to have the opmrtmnity to
prepare a sectim on "EEG in Psychiatry" for the. second
edition of the Commehmiue Tex/time}; 05 PA gravid/Ly.

I

am

I

assume

that the dates for this material am

as the section
My

best

cm

”Ccmmters

smci

Paychiatzy."

the. same

team .
Sincerely yours ,

.we

"-4,."

.r-

Yrs-mu

Fink, PM).
Pr'ofassor of myCMatw

ﬂax.
m1!"'wfwwwvv

‘lllrw'zm'rv—xwrv-

urn-

“W'l

-r

wmu-mv

:

W,“

mwﬂwmv'm

v-nw

HF :kp

�</text>
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                    <text>March

I».
;

a,

1959

Leon Eiserbez‘g

Department of Psychiatry
Harvard University Sd'xool of k’adicine

‘

Bostm, mssacmset‘ts
Dear

um,
Cmgrmlatims

of this Associatim.
and would
My

on your electicn as Vice President
I would like to make up rm: statimery

mists your preferred address of mead.

‘

best wishes.

Sinmly yours,
Fink,
Secretary

Max

MFsz

“1"

£1.13.

in

�</text>
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                    <text>Ham-h

s,

1989

Mr. R. Keith Carmen

Btewtivc Secretary

Canines

on

Problm of

Drug Dependence

Natimal Research Cumcil
Division of Medical Sciences
2101

Constitutim

Avenue

washingtm. D.C. zone
Daar Mr. Carmen:

at

Enclosed are the final copies of three reports presented
the MAS-ERG meeting in California for your midemtim

for inclusion in the

mittee.’

Thank you

1969

mm of the proceedings of the
'

for the opportunity to participate in this meeting.
Sincerely yours ,
Fink, rm.
Professor of Psychiatry

Max

�</text>
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                    <text>March

4. l969

Er. Fritz A. Freyhnn
St. Vincent's Hospital
l53 Nest llth Street

new York, new York lUOll

Dear

Fritz,

It

was kind of you to participate in our resident training
program. The residents, as well as my staff. enjoyed your
discussion very much, and I hope that we will have an Opportunity

to continue this type of dialogue.

With reference to your letter about the APPA, I share
your feelings. In addition to the suggestions in your letter,
which are important procedural changes, I think we must_rsappraise the role of the members. The younger members are
discourages from submitting titlns, for they sons know that the
programs are dictaﬁndle. Our sense of participation is
frustrating and the only connection between ourselves and

the society is an identification with the leaders. Since
these change annually, there is little time for them (or
ourselves) to develop the relationship which would encourage
participation. No organization has over succeeded in maintaining

its

membership when

it has

been autocratic.

Another aSpoct is exposure. The present ways of advertising
the program soon to be inadequate to achieve the kind of attendance
that we wish. This, despite the fact that we had more than lOO
requests for programs prior to the meeting. The subject was an
important one, the sneakers were excellent and yet, as I look
back I would admit that I contributed little to a successful
public presentation.
Perhaps

it

would be useful to most

discuss these ideas.

My

host regards.

at your convonétnco to

Sincerely yours,
Fink, MOD.
Professor of Psychiatry

“3X

,ME:kp

�</text>
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              <elementText elementTextId="38232">
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              <elementText elementTextId="38233">
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                  <elementText elementTextId="102904">
                    <text>W‘

waver”.

‘

,

,

-

V

‘1',

March 1:, 1969

Dr. Jamathan 0. Cole
Superintamlem:
Boston State Hospital
Boston, Nasaadmsetts 021%

Sear Jmathan,

mud

ﬂue
kind 911mg}: to
been.
This
has
canvulaive
ﬂ'larapy.
new for a manual of
cqnplataa and I am enclosing acme copies for ymr use. If
to make whatawr
it is aatisfactm, we amid be pleased
max-ants are necessary to run off my copies you may

may

mmﬂ'za ago you were

need .

a mthesiologist who is able to
Mt
manage complex convulsive therapy cases. I would mcmnj
You asked

W. Frank

22.

Wmn,

(212 875-5636).

I trust this

W6 East 88th

manual

Street,

New

York,

is Emlpful.
Sincerely ycnm,
Max

-

.
-

"HV‘V'T

MI?
V-IWJAz-n'

m“

A

7-m'rrf4

an...-

,.
...

my...»

at.

mme.w

wmmmmwzw

.,

Fink,

£41.13.

Mfeasor of Paydliatry

m-w

:kp

New

York,

v

FW/Jv'wnz-uyuw Jul-In~

W

�</text>
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              <elementText elementTextId="38243">
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                    <text>PM “my"

‘m-VW'W' .— "‘W' ww—

Wmn‘w'w-“m

v

Tum“ mm: :Wm/N-

.

wan-

E

E

5

March

3, l969

Dr. G. Verdeaux

Centre Psychiatrique Sainte-Anne
l, Rue Cabanis
Paris XIV, France
Dear Professor Verdeaux:

for

if

As I

returned from

a 2-page

abstract.

my

It

holidays, I found your request
is enclosed, with my apologies

the delay has inconvenienced you. A shorter abstract
was sent in December, and this will replace it.
As you suggest, I will be pleased to
present our
computeerEG data, but most usefully in the framework

of our present operating theory.

I look forward to working with you, and thank you for
kind
remarks. we have learned something since 1961 and
your
I trust the meeting in Liege will permit its expression.
My

best regards.
Sincerely yours,
Fink, H.D.
Professor of Psychiatry

Max
MF : kp

�</text>
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                    <text>June 24. 1969
Dr. Gaston Castellanos Villages

Instituto Nacional de Neurologia

Insurgentes Sur 421
Mexico 7. D.F.. Mexico

Dear Dr. Castellanos-Villegas:

After our pleasant meeting in Liege. I had the
fortune
to be discussing our studies of cyclazocine as an antgood
depressant
with Burtrun Schiele: and he told me of your interest in this
problem. Trusting that your interest has been sustained. I an
enclosin draft copies of the report we recently submitted for
publicat on. He found cyclazociee to be a useful antidepressant even more active than ieipreeine. although its narrow therapeutic
range will undoubtedly hamper its clinical use as an antidepressant.
You nay know that we came on the antidepressant activity of cyclazocine
from its EEG profile. A copy of that report is also enclosed.
"5““

'0

rurmﬁ-ﬂ:

interested in holding a meeting on the general
w th the World
subject of EEG and psychiatry in conjunction
Congress in l971. As it wil take some planning and support
will have to be obtained to finance attendance by some participants.
I am writing to ask whether such a meeting can be considered in
your plans. either as part of the con ress prograe or as an affiliated
meeting. If affiliated. I would be p eased to try to get the
sponsorship of some international research groups. as the International
Association for Psychiatric Research. or IBRO.
I an most

Again,

it was

a pleasure to hear of your

If the opportunity presents for you to visit
pleased to arrange a visit to our center.
Hy

interest in cyclazocine.

New

York. I would be

best regards.
Sincerely yours.
Fink. M.D.
Professor of Psychiatry

Max

r
w

.
r
was-drum

'

unw'wvwxn‘.

~.»

HF:kp

enc.

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