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                    <text>October 4, l§67
Dr. Joseph 6. Bird

Director, Division of Clinical Research

Sterling~winthrop Research Institute
Rensselaer, New York l2l44
Dear Joe.

Enclosed

institutions.

is

a proposed protocol

for the collaborating

In addition, the modification of our protocol is also
enclosed and I would be grateful for any criticism that you

have before I implement this. If the protocol is
agreeable to you, would you be able to supply us with

may

cyclazocine capsules with .25 mg cyclozocine in a pink
capsule as enclosed. I can obtain the imipramine from
Geigy directly. If this is not satisfactory, would you
be willing to obtain imipramine from Geigy and make up
matching capsules of 25 mg imipramine and .25 mg cyclazocine.
Sincerely yours,
Fink, M.D,
Professor of Psychiatry

Mex

Mszp

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                    <text>October 4, l967
Dr. T. P. 5. Watts
Geigy Pharmaceuticals

Ardsley.

New

York 10502

Dear Paddy.

Enclosed is the FD 1573 for ketimlpramine and an additional
copy of the proposed protocol. As we discussed. I would like to
have your comments,

I have already set into motion a program for the classifica«
tion of patients using the Hamilton Rating Scale.

I enjoyed lunch.

My

best regards.
Sincerely yours.
I

Fink, rm.
Professor of Psychiatry

Max

Mszp

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                    <text>'=

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October 3, 1967
Dr. Bernard C. Giueck

Institute for Living 690

Hartfordglgonnecticut
Dear Buzz,

Enclosed are two copies of our report “Digitai Computer
Research.“ The figures
Analysis of the Human EEG in Psychiatric
soon as
are incompiete but glossy prints will he sent to you as
I

them from the photographer.

get

mcawor

wan-WA

83070

Thank you very much

"M

for this opportunity.

My

best regards.

‘Sincereiy yours,

Wm"

c-

Fink. H.D.
Professor of Psychiatry

,.

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                    <text>.

Octaber 4, 1967

ﬁr. Richard P. white
Associate Professor
The University of Tannessee
ﬁepartment of Pharmacology

ﬁemphls, Tennessae 38l63
,A

_

nwvar.

:“Nv-Nw'wxlsn

Bear Dick,
With regard to the buéget requést 9f expenditures on the
cyclazocine project, 1 do net thlnk that we are able to approve
either equipment or travel since these are RIB rastrlcted
categories. The funds allocated are for “Cansultatlon” and
that these may be expanded as consulta-’
it is my understandingmembers
tion fees for you or
of the staff of the University of
Tennessee or may be transfernd to other unllm1ted categories.
such as personnel or supplies.
Inﬁofar as our travel funds on this project are restricted
and limited we are unalla ta apprave this speciflc request.
-

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map-FIv-wvti'm'qv

ﬁbuld you please submit a revised budget including only'
allowable items.

‘m'

V

Good

,

luck!
Sincerely yours,
Fink, $.8.
Professor of Psychiatry

Mai

.

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Dr. Freedman
Dr. Morgan

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                    <text>Frau-mnwxmuwwm-wm-wrmwmw-«er-w

-

t

—

&lt;

,m

_

_-

..

,.

.

AhJ-‘mw‘r'rnfwrWmmvﬂmwm

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drawn”- ,.—:rw—v~a-smmrnwwwmvnw-w«um-w,

MNV'11'§

«Wyn. "J—Waﬂ-w..—"

i

camber 3,

1967
‘

Miss Yulmen Cig

Missouri Institute of Psychiatty
5400 Arsenal Street

.

‘

A.

St, Louis, ﬁisseuri‘63139

,

,

IDear Yulmen.
.

Would you

and obtain
I need the
may

please

Also. ask for

wish.

of the enclesed figure.
glossy prints from your photographer.

make up a graph

eight
prints as rapidly as
5 x 7

But

2

x 2

those-is

you can

get

them to.me.

slides for ﬁe and any that your uncle
n9 rush an the slides for me;
‘

figure the three graphs should be made 0f distinctive
but
at the points marked .01, .05 and .001 please put in
tape,
some symbol like a triangle, square or star.
In the

Please bill
which

me

at the

New

York Medical

Incidentally, I will be sending you
there will be no rush

College.

some

others about

Sincerely yours,
ﬂax Fink, M;D.
‘

liF: kp
Hi!

Kathy

Professor of Psychiatry

-.=~-- v,

awn»...

I'nn-' '~A&lt;{1:u-v‘- 7...“.

�</text>
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                    <text>September 28, 1967
Dr. William Triebel
Medical Director

Gracie Square Hospital
420 East 76th Street
New

York.

York

Bill,

Dear
and

New

Enclosed is a copy of our application as submitted to
five additional copies without the financial pages.

NIMH

this proposal to the
appropriate committees of Gracie Square Hospital for their
review and approval.
I

would appreciate your submitteng

I want

cooperation.

to take this opportunity again to thank you for your
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:kp

enc.

�</text>
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2mm,0" new
ﬂ’mv'mwx’wnwur

—“"'5‘"

mmmm‘"

September 28, 1967

,

Dr. Lothar 3. Kalinowsxy
115

New

East 82nd’5traat

York, New

ank

10028

Delr Lothar,
Enclosed is a copy cf the appIication for support of the
study of ECT at Gracie Square Hospital. I want to thank you
again for your help and 100k forward to undertaking this study.
My

best regards.
Sincereiy yours,
Fink. M.D.
Professor of Psychiatry

Max

MRkp

enc .

A

&lt;

�</text>
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                    <text>September 28, 1967
Mr. Dona1d B. Cheetham,

Jr.

Research Associate
C1inica1 Investigation Department
Smith K1ine and French Laboratories
5500 Spring Garden St.
Phi1ade1phia. Pennsylvania 19101
Dear Don,

the research circu1ar on SKF 14336 with a great
interest. Whi1e I think the study is appronriate, I do
not be1ieve that the target popuiation that is 1isted in the
protoco1 can be made avai1ab1e at our hospita1 for a number of
months. For this reason I wouid ask to pass.
I have read

dea1 of

Thank you very much for the opportunity to read this information
and I hope that we wi11 have an opportunity to participate in another

study.

My

best regards.
Sincere1y yours,

Max

Fink. M.D.

Professor of Psychiatry

Mszp

�</text>
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                    <text>2:
A

'-:;&gt;‘"-‘

7».

-v-'

—v.

:.-,-;-—.n-

;7

warmer-gr:-

September 28. l967
Dr. Nafi Kiremitci
8396 Big Bend Boulevard

webster Groves. Missouri 63ll9
.

Rafi.

Dear

discussed your request Iith our chainsan, and
at the present time to make an additional
appointment within this department.
I have

it not possible
‘

it

you requested. I have made a number of calls on your
behalf and I believe that an appointment may be available at
the New Jersey State Hospital at Marlboro under the supervision
of Dr. R. P. Henna. He has an extensive research program under
development and is seeking an aggressive research leader. The
programs are affiliated with the new programs at Rutgers
University Medical School! I have written to Dr. Memo on your
behalf and suggest you contact him. Some data on the hoSpital
follows.
As

My

regards to Betty.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

cc:

Dr.

Itil

�</text>
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                  <elementText elementTextId="102315">
                    <text>September 28. l967
Dr. Leo

Hollister

Associate Chief of Staff
Veterans Administration Hosﬁital
Palo Alto, California
Dear Leo,

to take this opportunity to thank you for your
my associate, Dr. Jovan Simeon. He has returned
from his visit to California quite enthusiastic about the work
in your laboratory.
I want

hospitality to

recently been asked to consider a study with
I recall that some years ago you were quite
enthusiastic about this drug and I would be grateful for
any reports that you may have prepared in your studies.
I have

oxypertine.
Many

thanks.
Sincerely yours,
ﬂax Fink. M.D.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>I». wvu

«am--

September 28, l967
Dr. Robert P. Nenno
Medical Director
New

Jersey State Hospital
New Jersey 07746

Marlboro.

Dear Dr. Nenno:
I have read the information which
you made available
me
regarding the Marlboro State Hospital with a great deal of tointerest.
I have discussed this research
opportunity with two of
former
associates at the Missouri Institute of Psychiatry. Dr.myNafi Kiremitci
has indicated an interest in this position and may write to
you

separately.

I met Dr. Kiremitci when he was an
assistant in
York State Psychiatric Institute in l96l. He psychiatry at
returned
Turkey to complete his military duty and was appointed to the to

the

New

Missouri

Institute of Psychiatry in July l965.

He has been actively involved in the
research programs there.
especially in the studies of new compounds as they effect
behavior
of the severe mentally ill. He has an experience with populations
similar to those at the New Jersey State Hospital.

has recently completed the requirements for licensure
and is scheduled for the examinations of the American
Board of Psychiatry at their next meeting.

in

He

two

states

I believe he may be helpful in your program and
trust that he
In the interim, a copy of his curriculum vitae

will write to you.
is enclosed.

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                    <text>September 28, l967
Dr. William R. Tabor
Director, Medical Research
A. H. Robins Company

l407 Cummings Drive

Richmond, Virginia 23220
Dear

Bill,

Enclosed is a protocol for a study of Repoise - syrup
which has been submitted to the appropriate committees for

expect that this will be obtained within
a month. By that time, I will have had the chance to discuss
the protocol with my full staff and the study may begin in

approval.

early

I would

November.

.

If this protocol is satisfactory,

and as soon as you
have submitted
to the FDA, please call me and we can
discuss the supplies that will be necessary.

it

Thank you

My

for theoopportunity to consider this study.

best regards.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>September 27. 1967
Dr. Werner P. Koella

Senior Scientist

for Experimental Biology
Shrewsbury. Massachusetts 0l545

The Worcester Foundation

Deer werner,

Enclosed is a final copy of the paper called “EEG Patterns
of Cyclazocine, A Narcotic Antagonist.“ which has been revised
following your suggestions. I believe this is much clearer and
I have taken the liberty of bringing some of the experiences
up-to~date.
I have withheld the
I believe the story

me.

satisfactory.

My

figures because none have satisfied
is clear as presented and I trust

The other report for the l967
best regards.

ACHP

will be ready shortly.

-

‘

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp
BBC.

�</text>
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                    <text>September 27, 1967
Dr. Paul Blachly

University of Oregon School of MedicinePortland, Oregon
Dear Paul,
Thank you very much for sending me a capy of the
proposed
symposium at the forthcoming APA meeting. I hope that the
Program Committee will welcome this suggestion and I look

forward to participating.

It has been almost eight years since I participated in a
study of convulsive therapy, but your suggestions for HMECT and
the enthusiasm for unilateral ECT has stimulated me to under~
take another ECT study project. In my present facilities at
Metropolitan Hospital, the number of cases treated with ECT
are quite few and I have sought the cooperation of Dr. Lothar
Kalinowsky to study cases at one of New York's largest treatment centers. Gracie Square Hospital is well known as a center
ECT.
for

would like to obtain some support from the National
Mental Health and in doing so I would like to be
able to call upon you and Dr. Kaelbling as consultants. As
the originator of MﬁECT, I know of no~one more qualified to
advise us in the most satisfactory method applying this technique.
We

Institute of

May I have your permission to include your name
among the
consultants for the study ITheoretical Clinical Studies of

Convulsive Therapy?”
Many

thanks.

My

best regards.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>September 27, l967
Dr. Robert L. Kahn
Department of Psychiatry

University of Chicago

Illinois

Chicago,

Dear Bob,

After a hiatus of eight years, I would like to undertake another study
of convulsive therapy. The recent modification of multiple monitored ECT
and unilateral ECT have stimulated my interest. while we have only a few
cases in treatment at Metropolitan Hospital, I have been fortunate in
obtaining the support of Dr. Lothar Kalinowsky and the staff at Gratie Square
Hospital and would like to undertake this study at that institution.
writing to you today to obtain your permission to include you
among
list of consultants whose advice I may wish to call upon as
we become involved with the details of this project. As you may guess
I am applying for support from NIMH and would like to make this a
definitive study involving many of the suggestions which were made
during our active days at Hillside.
I am

the

May I

have your permission?

Incidentally,

and I did so with a

recently invited me to give a talk at Hillside
great deal of enthusiasm. I found the hospital unchanged.

Hal Esecover

Pollack and

Lurie were old faces in the audience. The
interested in the topic which was “Computers
in Psychiatry." I visited the laboratories and was surprised to find our
old tape recorders, the apparatus built by Eric Karp and many of the tapes
which you had made still on the shelves. The EEG laboratory now has a second
machine and they are particularly involved with a detail ofihe EEG known as
Mitten patterns. There is much talk of building a research building and I
was surprised to hear that our old plan had been puled out of the files and
an application resubmitted to NIH for support at the same level as we had
tried eight years ago.
Don

Klein.

Max

residents were bright

Abe

and most

I trust that Dan Freedman was kind enough to extend my regards. We
met some months ago in Washington and had a delightful discussion of your

programs.
My

best regards.
Sincerely yours,
Max

Fink,

H.DD

Professor of Psychiatry

Mszp

�</text>
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                    <text>s.»

L

E

E

is

E

September 26.

erw‘r—w'”

qﬂywrn

1&amp;6?

Hr. Stefan Began
Senior Research Associate
8epartment of Medical Investigation

Inc.
Jersey 07118

Hoffmann~La Roche

.w

”RF-WW

iWA’c-ﬂfv-

Nutley,

ﬂew

ﬁear Mr. Began:

—'

,,,,

_

r-Ht,‘

«

In order to continue our teaching program would it he
passible fbr you to send as 5,000 capsules of Librium placebos.
25 mg each?
.

«awn-mun

Many

thanks.

—!w-wr‘

Sincerely yours,

1w»

nw—v‘rru,

gamma-u

Max

,

Fink, H.D.

Preféssor of Psychiatry

k?

wwwu

mww—u— .7"

"3v”

11

L

«r

�</text>
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                    <text>September 26, l967

Division of Research Grants
Public Health Service
.

Bethesda, Maryland 200l4
Gentlemen:

are anxious to apply for a U. S. Public Health
Service Grant and would request two application Forms PHS-398.
We

May we also have a copy of the supplemental instructions
for "Grants to Institutions Outside the U.S.“ and for program
projects and centers?

Sincerely yours,
ﬂax Fink,

”.0.

Professor of Psychiatry

Mszp

�</text>
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                    <text>September 26, 1967
Dr.

Philip

8. Bradley

Center for Advanced Study in the Behavioral Sciences
202 Junipero Serra Boulevard
Stanford, California 94305
Dear

Philip.

Congratulations on your opportunity to study in California.
the opportunity fulfills your expectations, for it has
been spoken of most highly by so many scientists who have preceded
I hope

you.

I am writing to obtain some up-to-date information regarding
the book "Anticholinergic Hallucinogens.” Are all the galleys
and page proofs approved? If not, are there any further page
proofs that should be checked?
_

Is there anything else that has to be done? Or, am I to
that the editorial work is completed and we are merely
awaiting the publishers details?
assume

Incidentally, I have interested Dr. white in a study of
an anti-narcotic, cyclazocine, and hope that he will have this
work completed before he joins you in England next year.
My

best regards.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

Mszp
P.S.

If

you have a few minutes, please

(212) 369v8488.

call

me

collett at

�</text>
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                    <text>September l8, l967
Dr. Michael C. Barry
Assistant Medical Director

white Laboratories, Inc.
Kenilworth, New Jersey
Dear Dr. Barry:

Both Dr. Itil and I are grateful for your consideration
of our request to undertake a study of fluphenazine in high
dosage in the populations in Istanbul and St. Louis. Your
willingness to file the necessary forms for an IND with the
Food and Drug Administration will be most helpful.
Our estimate of the supplies necessary to undertake th
study in Istanbul is as follows: for 20 patients, l0 weeks
observation at 400 600 mom/day will require 700 gms
fluphenazine. To provide for loss and drop—outs we will
ask a supply of lOOO gms.
—

best form would be in liquid concentrate, at the
palatable concentration, but not less than 20 mgm/cc.
the
concentration
If
is 20 mgm/cc, the amount will be 50 liters.
The

maximum

If tablets are more feasible, then 50 and 100 mgm tablets
should be considered, and the supply requested would be 3000
tablets of 50 mgm and 7000 tablets of l00 mgm.
discussed, we will try to obtain the funds necessary
for this study by diversion from other study programs, but this
source is limited, and we would ask White Laboratories to
consider an additional grant-in-aid in the amount of $l.000.
As we

Thank you

for your consideration.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

cc:

Dr. Itil
Dr. Polvan

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                    <text>September 16, 1967
Dr. Hilliam Triebel

Gracie Square Hospital
420 East 76th Street
New

York.

Dear Dr.

New

York

Triebel:

Enclosed is a draft of the grant application for the
preposed study program at Gracie Square. I would be grateful
you and/or Dr. Ross would read this and we can discuss it
if
when we meet. I will call your office on Monday if I haven't
heard from you sooner.

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

MF:kp
ENC .

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                    <text>September 16, 1967
Dr. Lothar B. Kaiinowsky
115 East 82nd Street
ﬂew York. New York
Dear Lothar,

Enciosed is a

draft of the grant application.

I yould

and make any corrections or
if
suggestions. I wili caii your office on Tuesday or Wednesday
to make an appointment to meet with you.
be

grateful
My

you would read

it

best regards.
Max

Fink,

M.D.

Professor of Psychiatry

Mﬁckp

�</text>
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                    <text>September l4, 1967
Dr. Charles Shagass
Temple University

Department of Psychiatry
Philadelphia, Pennsylvania
Dear Charlie:
I didn't forget your request but couldn‘t find this
reference to Ormsby until this minute, since my files are
still chaotic at home. The preper reference is: Drmsby, J.F.A.
(l96l) Design of numerical filters with application to missile
data processing. J. aaa. comp. mach. 8, 44D~466.

join

Turan has
him

in his

told

me

of your discussion and perhaps
you at the end of the month.

visit to

Please thank Clara for
regards.

an

excellent dinner.

My

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

I

will

best

�</text>
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                    <text>September 13, 1967
Dr. Edward Woodward, Jr.
Robins Company, Inc.

A. H.

1407 Cummings Drive

Richmond, Virginia 23220
Dear Dr. Woodward:

for your letter of September 8.

I think your
in
the protocoi for the investigasuggestions regarding changes
tion of fenfluramine are most heipful and acceptable. Piease
alter the protocol and send me a copy.

Thank you

Many

thanks for your cooperation.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>September 13, 1967
Dr. Aiain Sanseigne

Associate Ciinicai Research Director

E. R. Squibb and Sons
Georges Road
New

Brunswick,

New

Jersey 08903

Dear Alain,

Enclosed is the latest reVision of the depot fiuphonazine
study as changed by us on Saturday. Please see page three.
I enjoyed being with you.

My

best regards.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MszP
GﬂC.'

�</text>
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Miss Georgia Gorian

University of Minnesota
6908

l4th Street,

South

Minneapolis, Minnesota 55423
Dear Miss Gorien:
Thank you very much

interested in appointing

for your letter.

I am very much

an additional EEG technician. I
know of Dr. Torres' work and would be pleased to consider

your application.
New

I

Enclosed

is

application blank from the
College, and if you will send it to me,
reviewed by the personnel staff.

York Medicll

will

have

it

a formal

please indicate in the application your
permission to call one or two references.
Would you

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

MF:

kp

�</text>
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                    <text>September l2. 1967
Research Fellowships Sect1on
Behavioral Sciences Training Branch
National Inst1tute of Mental Health
5454.wisconsin Avenue
Chevy Chase, Maryland 20203
Gentlemen:
At the suggestion of the Chairman of the Department.
Dr. Alfred M. Freedman, I an writing on behalf of a resident
physician who is now in his third year and to whom we would
like to recommend the Mental Health Research Development
Program. We would appreciate an application kit and the
instructions for submitting an application. It is my under~
standing that either Dr. Freedman or I w1ll act as sponsor
and the candidate, Dr. Arthur Zaks,w1ll be CGMpleting his

resldency training in June of l968
Thank you

for your cooperation.
Sincerely yours.
'

Mszp

Fink. M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>September

ll.

1967

Krohn~Hite Corporation

580 Massachusetts Avenue

Cambridge, Massachusetts 02l39

Gentlemen:

are anxious to get a set of filters which may be
suitable to use for the modification of EEG signals before
analysis. Would you kindly send me a cepy of your catalog
describing your line for this purpose and the name of your
closest representative in New York?
He

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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Mrs. Mina ﬁatheson

Missouri Institute of Psychiatry
5400 Arsenal Street
St. Louis. Missouri 63l39
Dear Nina,
few visits to St. Louis,Dr. Itil worked me
so hard that I had no chance to visit you. Houevor. I did
meet Don Sundland and was pleased to hear of your project.
During

my

Recently Jovan Simeon shared with me one of your monthly
envelopes and I was pleased to find at least four articles
that I had not seen before and which were of further interest
to my present program. Would it be possible to extend your
service to an ax~Missourian7
My

best regards.
Sincerely yours,

via".

-.

'1er;

~4i—O‘J

Fink, M.D.
Professor of Psychiatry

Max

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September 8, l967
Dr. A. Arthur Sugenman

Chief. Investigative Fsychiatry Section
Eureau of Research in Neurology and Psychiatry
c/o ﬁew Jersey Neuro~Psychiatric Institute
Box

000

Princeton,

New

Jersey 08540

Dear Arthur,

Enclosed is the application and

corrections

a

set of suggested

which have been added to the xerox copy. Please
note the corrections in the eqiipment and supply costs.

Please call

me

if

there are any questions.

Good luck!

Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MFtkp

'
V

&lt;muvgruv

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"H,

u.

:wn-wﬁ’r'WW-JJVIAJ'I- ‘4“ it?"

w

'iiﬂY'rWN'mWﬂW‘K\.u~wn'

-\.,,.~u-m.‘,~&lt;:r—mum-v map-a7.— ew‘

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inhuman.

,rv-

September 8, l967
Dr. Heinz E. Lehmann

Clinical Director

Douglas Hospital
6875 Lasalle Blvd.v
Verdun, Quebec
Canada
Dear Heinz,

'.»'Y“',

w-

rm

n‘3“

.stwiw-r-c'mrmmnl‘vmmynt

n
an

mm

w-n:

h":€-I«KW

I am grateful for your kind reception of the suggestion
that cyclazocine be discussed at the antidepressant panel. The
provisional title is "EEG Patterns Relating to Clinical Anti~
depressant Activity."
I would plan to review the EEG profiles of the known antidepressant drugs, describe the profile of cyclazocine and then
give an up-to—date report of the clinical studies of cyclazocine

as an antidepressant.
I

will try to

as requested.
My

have a copy of the paper to Dr. Hittenborn

best regards.
Sincerely yours,
Fink, M.D.
ProfesSor of Psychiatry

Max

HF :

kp

a!

a‘ “v.

.--~r—.

.4l.""

,—«~ ~

.

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i
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September 7, 1967
Dr. Louise Speck
CNRC

St. Eiizabeth's Hospitai
Washington, 0.6.
Dear Dr. Speck:
EEG

As I suggested in May, my iabaratory for quantitative
now operationa] and I would be pleased to have you
us.on your next tour through ﬂew York. The laboratory

is

visit

is in the Department of Psychiatry offices at

at the corner of Fifth
369—7900

Ext. 245.

Avenue.

I

5

can be reached

East

at (212)

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:kp

102nd

St.

.~

.-..

�</text>
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                    <text>..

v-mw-

.v-n

.1..-

Wuwnr'J—vvr

September 7, 1967

~

Dr. Alain Sanseigne

Associate Clinical Research Director
E. R. Squibb and Sons
Georges Road
New

Brunswick,

New

Jersey 08903

Dear Alain,

Enclosed is the revised fluphenazine decanoate/enanthate
Thank you for your help.

project.

'

In our discussions I believe we indicated that we could
after
start a few patients on oral fluphenazine immediately
the placebo period as a priming treatment. Or. Bucci seems
to recall this and was asking me for some fluphenazine. If
this isﬁagreeable, I will modify the project so that in
selected cases he will be allowed to use a priming dose.

tablets) of Prolixin
hydrochloride in the largest available amount (5 mg)? Thank
Would you send me a supply (lOOO

you very much.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Hszp

�</text>
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                    <text>~‘vv‘uﬁ an):

Wﬂr'v‘r‘mW-leﬁ

,

»

A

. “vat—W
F

«w ‘"man-ra—vm—r.

r_. n

v

.

.

u.

~‘~L,ern~

J-wwwww'wrw'mma‘wnu”II-FWAMF'I'MW‘WVQ

:

,'(1'"'V‘Iu‘:=an‘ﬁm-mut1ﬂiw~rv-vr‘m,’

September 5. 1967
Dr. John Kramer

.
A.

_.H_

..

Chief of Research
Department of Corrections

Caiifornia Rehabiiitation Center
P. 0. Box 841

._..

W

“I“?

m

Corona, California

_
..

wary,“

Dear John,
be giad to have you visit on September 19. As you
can tell, the Brotman proposal is a straight socioiogicai program
quite distinct from the medical ~ pharmacological approach that

wiii

He

'rm'mamwg-WW;.

we

use

at Metropoiitan.

If

you

get to Great

(516)‘466-3158.

room and I can
My

If

ﬂock on Sunday. give

you wish to stay over

take you in

on Monday.

we

me

a

ring at

have plenty of

best regards.
Sincerely yours.
Fink, Moﬂ.
Professor of Psychiatry

Max
.1”;

Mszp

,

,

o,

g
{w’vp

wrnw1.v—.».

.‘,":"lu&gt;,

«w

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New

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2mm:

awar-

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�</text>
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                    <text>Soptomber 5, 1967
Dr. Ralph Jacobson,

Associate Medical Director
Endo Laboratories. Inc.l
'.l000 Stewart Avenue
Garden City, New York_ll§33 [
.

Dear Dr. Jacobsenzv

'

Thank you very much for the initial supply of naloxone
20 mg tablets. Qur
two patients are now.taking 100 mg
a day and the second group of'threo patients will start on
Monday. If all goes well, we.will neeo an additional supply
by the lst.of October.

first

‘

.

Concurrently we have carried out our acute naloxono
experiments_using the_0.4 mg per cc Concentration. Haloxone2 mg offeCtivoly blocks_20 mg of heroin.
I an anxious to
continue this work and will soon need an additional supply
of injectable naloxone. hopefully at.a higher concentration.
I would bo-grateful if an additional supply could be made
*available. Please call me when you have some information.
_

Sincerely yours,
“1-

#rofessor of ﬁsychiatry

,1"

Iu-‘I‘vr‘rf'

I

.,,,mv,.-,w~v-u,y~,.

..
y

.

MF:kp

.

�</text>
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”-"erwyw

September 5, 1967
m-w...'..,_‘...,...

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Spero~whitelaw 50., Inc.
385 Park Avenue South
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York 10016

n.

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—...,

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—

I should like to discontinue the malpfactice insurance
described in the attached certificate.

-w'~Yl‘-4vr"vvv

Thank you

.wm.

for your cobperation.
Sincerely yours,

.v‘mcuuw,

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ﬂax Fink. M.ﬂ.

mar-1

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r.

NF

...

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., .,. ‘-kmnwrrwvw'.rvw‘_WWW-N'

.

'mmm

Sebtembék 5, 1§67

‘

Dr. deﬁes H;

Satterfieid

:theways Hespitai

7
1891 Effie Street
Los Angeies; California 90026
’

h

.

Dear Jim,~

I was pleased t9 receive your letter far I have knewn ef‘
Gateways HQSpita1_for some years and'am daiighteé that this
fine institutien wiii have your suppart.r Knowing of its

‘

-"

similarity_tQIHi}iside Hospita}, I-was pieased to discuss the
deveiopment of research programs with the Ziskinds on many
occasiQns during the past fﬁw years and was mast enccuraged
by their forward iocking point 9f View; 509$ luck!
I am pleased t6 ehcibse a few of the availabie preprints
of studies recently compietad. This work was done at the
Missouri Institute of Psychiatry using the 18% 1710'~ 1620.
-

&lt;

system which I estabiished

there...

I do nct know of
.
anyene usiﬁg t iink computer succeésfuiiy
in the anaiysis of EEG signals except itS'RideSstad use for

averaging evoked vetentiaIS;

,

"

'

Please give my persenal'regards to Seth ihe Ziskinds
next you see them;

when

.Sinéereiy yearsg.
.%ax¢Fink,*%.2§.

Professor cf Psychiatry‘

:Mﬁfkp

�</text>
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                    <text>September 5, l967

Editor
Psychiatric Progress

Mr. Harold Mehling,
3 West 57th Streeti
New York, New York

rt

l0019

~—.‘

v

Dear Mr. Mehling:

-"«'

4”

w;.—

—

'1)in

:‘HNVPv'a-r

avg—39‘:

vwz,

“”""-mlvv'.__

'v

that

Thank you for your letter of August 29. The presentation
I will be making at Hillside on “Computers and Psychiatry”

of the report published in the recent textbook of
psychiatry pubaished Iy Freedman and Kaplan, Milliams and Wilkins.

is

a summary

Additional information is being published in a volume
A copy of this article is enclosed.

Kline and Laska.

Sincerely yours,
Max

-.n-._—.y

.51“-

Hszp

7

’21:.me

Lm-r

WI"

:‘DETTVE‘W:

wwmrm

.qar:

”wage-A

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‘5'.
Km"

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can

ZW'VEL‘YE‘I":

z
expiry-H"

‘

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h

Fink,

M.D.

Professor of Psychiatry

r

by

�</text>
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                    <text>4mwu....~w-_‘.vwaw”, ., «ya-MW} 7w:
.

Ixszwr'u —..——

"Jr!"—

September 5, 1967

Br R1chard P. Mh1te

Associata Professor of Fharmaca1ogy
Department of PharmacoTagy
The Un1vers1ty of Tennessea
’

1

‘

Memphis; Tennﬂlﬁge
Dear D1ck

to comp1ete ynur app11cation to the ﬁat1ona1
Science Foundat1on. I hape that th1s w111 go through.
I was 91eased

Enc1osed 15 a suppiy

stué1es.

During the

past

narcotic potency of

of 50 mgof

d1acety1morph1ne For your

few weeks, we have been assay1ng

Haloxene and

find that this

15

the anti—-

immediately

,

1,.

effect1ve 1n bTOCking the cantra! and behavioral effects of
hero1n In our subjécts, 2 mg ef NaToxona effect1ve1y antagonizes
20 mg of d1acety1morph1ne and does so when g1ven twenty m1nutes
before or twenty m1nutes after the hero1n. Perhaps after you
have had some exper1enca with cyclazocine, you shoqu plan to
luck
‘

at this

compound as we11.

Good luck!
,

.

$1ncéreiy yours,
Hax F1nk

Prafessor efDFsych1atry
Mszp

.1

.-&gt;4.3ivaa_;.i,:g.A

�</text>
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                    <text>September

l,

l967

Dr. Joseph 6. Bird

Director, Division of Clinical Research
Sterling~winthrop Research Institute
Rensselaer. New York l2144
Dear Joe,

of the investigators you might consider
for the callaborative cyclazocine study. Dr. Allen Raskin can
be reached at (30l) 495¢l393. Dr. Itil can be reached at (314)
Enclosed

M1

5—6230

is

a copy

Ext. 618.

I would

like thlt

Dr. Jovan Simeon and Arthur Zaks from

this department also be invited to the meeting, since they
have been active in the cyclazocine study. While both are
away. I will speak for them and believe that they will be
available at any time after Septemher 22.
Sincerely yours,

Fihk, M.B.
Professor of Psychiatry

Max

MF:kp

enc.
3::
my

¢'

-.-v-.-::\

34;?er

:‘f"W—‘12'\r"‘7‘fw‘}'1fir

my.

law

'-.-‘

twain-1.x

..«.-,

mm

17-75];

,

�</text>
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Street

St. Lauis, Miasouri 63139
8aar Taran,
seconﬁ varsicn 0f the EEG~antiaﬁyrassaﬁi
ta thank yam {ﬁr
is much bgtter and i want
paper. I think
1ecat1ea of figurag»
your comments. Pieasa mate the saggestgé
fruﬁ
year collectiuﬁ
and if pessible, wauEd you saiect fiﬁures
Gags thai
ma.abeut’the
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at these piacas.,
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them in;
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Enclosed

is the

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fit

abarmacwlegy
SecaﬁQIy, thera is a draft of-tha c11wica1
stil? in”
is
table w1th all the.citat$an$ aﬁﬁ
payar. Tae majar
1w: ma
this
tc.se&amp;
like
campieie, but I trast you mightI‘am
revise
tn
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know what your cammants are.
I

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My

written

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tais shﬁuid

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be

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draft of the haﬁlucinegen

by Kathy an ﬁcnﬁay.

‘

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ragarﬁﬁv

Sincereiy yours»
Fink, M.m.
Professor 9 Fsycii&amp;try

Max

ﬁszg
enc .

'

_

�</text>
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                    <text>nv....«.-

:vn‘v

-~.——

”wry“

.

November 30, 1967
C. B. Mosby Company

3207 Washington

St. Louis, Missouri 63103
Gent1emen:

Piease enter

subscription for the journa1, Cttnicat

my

P1ease address copies to:

Phanmacoﬂogq and Thenapeutica.
Max

Fink,

M.D.

39 Ar1eigh Road

Great Neck,
Piease bi11

me

New

York 11021

at:
Max

Fink,

New

York Medica1 Co11ege

M.D.

Department of Psychiatry
5

East 102nd Street

New

York,

New

York 10029

Thank you.

Sincere1y yours,

Fink, M.D.
Professor of Psychiatry

Max

..1\":-r&amp;4'

.,..

c-n-w

-;

:r
...,

vir‘mx

v:m:.~,4~

,.--

�</text>
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                    <text>.4.»gk;"~'l7

Inv»

aw

av.“-

Law

—-.~y&lt;«

November 27, 1967

Dr. william Triebel

Gracie Square Hospital
420 East 76th Street
New

York. new York

Dear

Bill,
Thank you very much

study program.

staff

on December 6.

us get started in our
to attend the meeting of the

for helping

I am planning

.

Enclosed is a draft copy of a memorandum to be distributed
at that meeting. Would you please review this and if it meets
with your approval, return it with an indication as to the number
of cepies that should be made available.
Do

staff?

it best to distribute these at the meeting
general mailing to the attendings of the hospital

you think

or to have

a

_

Sincerely yours.
IMax

Fink, H.D.
Professor of Psychiatry

MF:kp

�</text>
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                    <text>November 27, l967

Dr. Merle Gibson

_

Division Neuropharmacological Drugs
Bureau of Medicine - FDA
Crystal Plaza
Arlington, Virginia_
Dear Dr. Gibson:
I am

writing at the suggestion of

the Psychopharmacology Research Branch,

instructions for filing

permit this

extracts.

Dr. Jerome Levine of

NIMH

the appropriate forms

to request

that

would

laboratory to undertake studies of marijuana
-

are interested in determing the clinical and EEG
effects of.these substances in volunteer subjects at the
New York Medical College. The focus of the study is to
determine the EEG profile and the concurrent behavioral
effect of parenteral administrations.
We

Dr. Levine has indicated that supplies will be available
from his office, as soon as we have complied with the FDA
regulations. Would you be so kind as to send me such information
as I may need to comply with the regulations?
Thank you.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                    <text>November 27, l967

Dr. Robert L. Kahn

Associate Professor
Department of Psychiatry
University of Chicago Hospitals and Clinics
950 East 59th Street
Chicago.

Dear Bob,

Illinois

60637

'

Perhaps the best way to describe the project at Gracie
Square Hospital is to review the enclosed application to eIHH
for support. I have always regreted that we did not complete
the study programs at the time that we were intimately involved.
In the ensuing decade. little additional information has been
published and I think that what we knew then is still much of
the information available today.
The

ECT

.

interest in multiple monitored

ECT and in unilateral
reevaluation
the
a
of
justifies
process. By utilizing the
I
me
available
to repeat and verify
hope
to
resources
today,
the observations we made then and add to them the rigor of more
should then
systematic collections. If the program succeeds,
be possible to write an important chapter in the history of
'

it

this treatment method.

I should like to be able to call on your experience since
think you can provide a critical judgment of the social and
—psychological aspects of these studies.

I

My

best regards.
Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

MF:hp

�</text>
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                    <text>“mm...“k.“&gt;mtmum‘gnm(~.,a~«row-3»
"tum“:mewt'nwuyw'apwhyr'17,..vn; _.

.... \w

,-

my”.

.,-.,.»~xo-m—m-n-w,.vmr

WHWW'WJWWW

-

\nw‘ .4“. av-m.:~vw-w—x~-m-v—rwun-mnfw

November 22, 1967
Mr. Robert Shearman
IBM

Corporation

411 Montague

Brookiyn.

New

York

Dear Bob.

just received and read the 18H Computing Report
for the Scientist and Engineer, Vclume 3, Number 6. This was
I have

very interesting and I note that aariier issues are availabie
through your office. 15 it possible to receive copies of
Volume 3, Nos. 1, 3 and 5?
Nany

thanks!
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

kn

.

-

,

�</text>
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                    <text>n
A»,

.«&lt;

«r

wrn—vm-mvwmmrm

v,

~11”

3.5."

my...

4—...wr.“... n,
q

"1~

v.

;nv—v-y'ﬂi"‘I'W‘W'J-MW*SWWWW'EtrLJv-,mp-Jrvgx v

InwptiT-s

Frv.‘ ..m.¢.mn—~~.¢w-m-

,an

,~rv.~wﬂwm&lt;wymwnm Y‘lan’vn‘JMHP‘r-umw»

J...” "my...

November 22, 1957

Dr. Alain Sanseigne
Squibb International
460 Park Avenue
New

York, New York

near Alain,
Dr. Denham

enjoyed the

visited with

visit

practitioner.

He

us

this

morning and I hope he

as much as I did. He is a charming experimental
sat in on a meeting with the patients and

their questions in a witty and enthusiastic
ﬁrs. Eucci ané Simeon joined me to discuss his
experiences with fiuphenazine and we found his reports interesting

answered some of

manner.
and

heipfui.

Thank you

regards.

for suggesting that

he

visit

with us.
r

Sincereiy yours,
Fink, %.9.
Professor of Psychiatry.

Max

MFtkp

My

best

Vina-"ulna suym- .j‘v‘g "mum

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                    <text>w—

w». ,va—u—ur-w-mn-ww-ur

'D«W.ﬁw up WM'rr-nawc-v

”:m'vkuMann

,

'mﬂv—umw-QW'"M'quvm-aumwnuuv\‘yvennvw'Wn-‘"

navember 22, 1967
"WV‘"-"'""','1"'

7w

?-

w“

Br. Pau1 Kay
15 Canterbury Road

Great Heck.

New York

-1

\r.“

..,

”yum—,(vr

Bear Pau1.
I have been ab1e

.,-

mw.

.—

,"y-v—w-e

presentation to the

to change the date for the

K1erman

Nassau MP Society to ﬁarch 19. Abe
Lenzner w111 prepare the program for April 16 and J. Stanton
can accept for February 20.

"a

"I

"a

‘4

v.“

~

I have ca11ed Br. Klerman and he is ab1e to come on
March 19. I am writing to him t0 confirm this change.

m

Sincere1y yours,

rowan-nun

".Hm-V‘

Fink, M.D.
Professor of Psychiatry

Max

HFtkp

.-r~ www- 'v'nvn.vw'rm-’w—-&lt;1'J

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’1

-2x

,

«rm—'11

lK-O‘WV'.

a
i

Rovember 22, 1967

Dr. Gerald Klerman
Connecticut Mental Health Center
34 Park

New

Street

Haven. Connecticut

Dear Gerry,

This is to confirm the change in the date of your
presentation to the Nassau~NP Society from February 20
to March l9. I will be in touch with you before that

date and
My

we can

discuss the details of your

best regards

and

my

visit.

thanks for your cooperation.

Sincerely yours,
Max

Fink, M.D.

Professor of Psychiatry

.Mszp
cc: Er.

Kay

�</text>
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                    <text>w “vs—v --~v.~

-

M'r'v- or .qu-wz-"Arw-w:
n—va

w- \z-um-V-srﬂ-I‘ﬁv, mun,

v,»

:: rip—w?- \wm

W'r31.1."? a

--

”Lyn-VMR‘YIEWW LY-new‘I—‘W'

I'Wl'nrA—J‘yx—

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7.,”

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‘

r, .I... .w

&lt;

mum..-

.,

my.- .

“wax.” “\“p--‘y‘y_:5v“' . 1..."...

ﬁovember 21, 1967

world Health Organization
UN Headquarters

First

ﬂew

Avenue and 42nd
York, ﬂew York

Gentlemen:

'

Street
‘

’

I havé just read of a new‘y'hub11shed repart by the
World ﬁealth Organization’s group on research in psycho«
pharmacology entitied‘“ﬁesear¢h 1n Psychopharmac0109y.“
Would you kindly indicate the ava113bi1ity and source
of this document and its cost?,
:

Thank you

for your coopération.

Sincérer yours,
Fink, M.D.
Professor of Psychiatry

'Hax
MF:kp

�</text>
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                    <text>5,,.,,,,.H..,.u,..:
x

:4

.,.,.

.74

new”,may,” Am-

-

. "‘f-!.-'»- w,

h

1..- -..,.v ,. ._-\j—:4rhe¢qy-v‘v-yw-vraFV-ﬂ,

November

3-, p—va' . ,v......_--..,-.¢-.-w:»‘Vm'm::r-.x|ry&lt;‘-W~NWVKav,'Vrmi.VmW,rv:u-,x
y"

WWI—(W:~.-;mqyuwmz

21, l967

Dr. Harvey Minchew
Bureau of Medicine
Deputy Director
Food and Drug Administration

Crystal Plaza

5

Zle Jefferson

Davis Highway
Arlington, Virginia 22202
Dear Dr. Minchew:

writing to request a copy of the selected bibliography
of marihuana. covering 1950 through l967, which has been prepared
by the FDA Medical Literature Branch.
I am

A

stamped, self~addressed envelope is enclosed for your use.

Thank you

for your cooperation.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MFtkp

'6

mm.

"-K\-‘(11I"F'

arm-m,“ rl'v.r"~ umv

�</text>
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                    <text>,,,. aamr-mzwwmw-u-nwvwwmm-smrut

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2l, l967

Dr. Daniel Silverman
269 South l9th Street

Philadelphia 3, Pennsylvania
Dear Dan,
I

have not forgotten the paper

for the

monograph of

EEG

to

effects. In response to a request by the
review the literature regarding EEG and drug effect for a
forthcoming symposium in Puerto Rico, I have devoted much
time to a detailed review of the extensive experiences in

and drug

AChP

the literature. The draft of the material presented at thew
EEG Society is unsatisfactory and I have delayeo sending it
to you pending some critique and review by my associates.
This has. and will delay my manuscript for a few more weeks.

._.

«._.1....,.¢,..I_.,_.,;,[

m'.‘h.(

v.7,

have read the minutes of the meeting and have made my
notes. From your letter. I assume weeare not bound by the
exact responses made at the meeting and I am taking the
I

liberty of responding to the questions to the best of
present ability.
I know how

only hope that

will write to

a delay means, but I can
be justified by a better product. I

exasperating such

it will

you

shortly.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

‘Max

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                    <text>(ﬂ-Kn,I“V-v¢.

‘Ygrﬁ‘u‘

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Dr. Werner P;

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1%?

Koalla'

Senior Scientist

‘

.

.

Worcester Foundation ib'r Experimental Eiralogy
Shrawsbury, Massathusetss-Ul546
Dear Warner,[

set your heart on accomplishing
the established mission of having all the ACNP manuscripts available
long before the meeting. I ragret that this will net be possible.
The original review of the literatura is on my desk, but this is
not a satisfactory presentation. in my discussions with Dr. Itil
hammered out a much
While I knew haw much you have

during the past few months, we have, I believe,
significant VlﬁW:0f the ralation of 5E5 changes with psychc~
tropic drugs to behavior., I would like to present a critical re»
View of our experiences and those of many other observers describing
the interaction of drugs, EEG and behavior in man. ‘This will he
available at the time of the meeting.

mare

the principal discussant of this summary. He
is intimately acquainted with my wcrk and with the total world
experience. ‘I have cansulted him and his discussion will comple«
meat the material which I am reviewing..
Dr.

Itil is

while I know this is less than satisfactory,.1 hope that you
will understand my reluctance to send you an unsatisfactory
manuscript; even far yaur ayes only, and hope that the delay will
be

justified
As

by the

results.

soon aS‘I have a

you ans‘arrange

ta

:

satisfactory document-I will send
conias as ynu request.

make as many

Thank yau for-yaurrinéulganca.

SinCeraly‘yours,
Fink, M.B.’
Professor cf Psychiatry

Max

HF:kp

it

ta

‘

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.,

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                    <text>vaember 21,

1967

Dr; Party Biack
Jehns Hopkins Hospitai
'

601 North.8roadway

Baltimore 5, Maryland

Dear

0r. Black:

writing with regard t0 the symposium "Drugs and the
Brain.“ You were kind enough to invite-me.to submit a manuscript
and I suddenly realized that the date for submission has passed.
I am

At the request cf the ACNP, I'am in the midst of an extensive
review of Iiterahure and wiii be pleased to make the kind of
presentatien which you requested, provided that the deadline

can be moved up to mid—Becamber. I shal1 try to have an'appropriate
manuscript avaiiabia for you by that time.
'

-

Sincereiy'yaursg.
'Max Fink, M.ﬁ.

Professor of Psychiatry

Mszp

�</text>
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                    <text>I-w

w.wumw~nmm~.;~m=wav-wr

.

November 21, 1967
Mr. Robert Shearman
13M

Corporation

411 Montague

Brookiyn,

New York

Bear Mr. Sheanaan:

Pieased be advised via this communication that the New York
Medica1 Coiiege Division of Biomedicai Information Processing
requests that the fo1iowing equipment be de1ivered to be attached
to the 2701 Communications Adapter.
7698 Synchronous Data Adapter
3855 Expansion Feature
3815 Extended Capabi1ity

of

As

you we11 know,

this equipment is being ordered in 1ieu

inabiiity to de1iver an adapter for the 1800. A January
1968 deiivery is imperative because of the deiivery of the front
end oquipment at that time and because of an already shattered
IBM's

time schedu1e.

This equipment is to bo bi11ed as part of the
Max Fink.

separate bi11ing statement to Dr.

Sinhere1y yours.
D. M.

Max

kp

Shapiro; 0.362 and

Fink,

M.D.

�</text>
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                    <text>ﬁovember 20, 1967

3r. Jernme Lev1ne

Psychopharmacology Research Branch
3133

Sethesda, 3ary1and

Sear

Jerry,

Dr. Freedman has suggested that we look at tetrahydro»
cannab1n01 with our EEG programs. As I indicated ear11er this
year, we wou1d be pIeased to do so when supplies are availabTe.
,

I have aIready f11ed an application witx Mr. G1ardono for
narcatic stamp 31th special permiss1on for mar1juana, and am
writing to ﬁrs. 3art1n and 133911 for permission to use the1r
pharmac01ag1c éata.
a

'

;

1

be

I am

f1led.

requast the necessary I33 forms
obtain these frcm your cff1ce?

wr1t1ng to
Can I

wh1ch must

take th1s apportun1ty to congratuIate ycu on your
For those of us 1nterested in the b1c1og1ca1 aspects
of psych1atry, the programs of the Psychopharmacology Research
3ragc? have prov1ded much of the leadership of the past decade.
Hay I

appointment.

Goo

uck!

Sincerely yours,'
33x Fink,

3.0.

Professor cf Psychiatry

3szp

�</text>
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                    <text>t

November 20, 1967

Dr. Harris

University of Kentucky
Lexington, Kentucky

Dear Dr.
We

g

E‘

i

i

Isbeii

Department of Psychiatry

Isbeii:
are interested in undertaking studies of tetrahydro»

cannabinoi and have been told by

own IND.

At

their suggestion,

NIMH

that

we

must

file

our

writing to ask your
permission to refer to the ﬁharmacoiogic data in your IND

when we

file

our own.

Thank you

May I

I am

have your permission?

for your cooperation.
Sincereiy yours,
Max

Fink,

M.D.

Professor of Psycniatry

Hszp

�</text>
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                    <text>November 20, 1967

William Martin
NIMh Narcctics Research

Lexington Kentucky
'

'

Facility

Dear Si11,
ﬁe would

like to undertake some studies with tetrahydro»

have been toId that we wii] have to file our
At 9?. Levine’s suggestion. I am writing to request
your permission to refer to the pharmacaIQQic data in'your
1&amp;3 when we file our own.r May we do so?

cannabinol.

own

Ifkﬁ

we

.

Taank you

for yaur ccaperatian.
Sincerely yours,
Fink, M.0.
Professor of Psychiatry

Max
HF : kt:

�</text>
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                    <text>November 20. l967

Dr. Donald F. Klein

Director of Research
Hillside Hospital

Glen Oaks, ﬂew York
Dear Sun,

In response to your request. enclosed is a list of my
puhlications. All the publications between l955 and 1963
resulted from work at Hillside Hospital. In addition there
are citations in l953, l964, l965 and l966 which are marked
in the list, which are predominantly the result of work done

at Hillsida Hospital.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>I

{W

.

,u—u

,

-w

Wur-w-rwn-x. ”at ..w
,

-.».m—-p.v. .‘ mm»,

was‘ «(w—www.mw—m‘W—"mvam—

I

E

ﬁovember 20, l967

Sr. ﬁilliam R. Tabor
ﬁ. ﬂ. Robins Company
l407 Cwouings.9rive
Richmond. Virginia 23220
ﬂoor

Eill,

Enclosed is an outline of an experiment to be undertaken
with‘the medical students at the How York medical College. As
part of the class demonstration series in pharmacology. this
demonstration is scheduled for January 9.

I would appreciate your cooperation in making available to
Supplies of fonfluramine and concurrent samples of amobarbital,
dextroamohetamine and placebo as outlined in the attached protocol.

we

'

If this is possible, the oxperiment will provide us with
additional information concerning the sedative or stimulating
Qualities of fenfluramine. I will complete the forms necessary
to consioor this research study. Many thanks.
Sincerely yours,
Max

Fink, $.9.

Professor of Psychiatry

ﬁszp

�</text>
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                    <text>November

'

Dr.

J.

M.

1!,

1967

C. Holden

Missouri Inst1tute of Psychiatry
5400 Arsenai Street
St. Louis, Missouri 53139
Dear Mike.
I

regret to

Say

that the

first report

of the

CﬂT

study

has not been accepted by the Aachéveé 05 Genekat Psychiaxng.
Perhaps you wou1d discuss with Turan and AIﬁ the aiternatives.
Surely. Campnahenbiva-Raychiatny or Psychophammacoﬁogia are

exceient Journals which may consider this report favorany.
For e1ther one, the references may have to be retyped.

If

I can be

of any help, piease call on

me.

Sincerely yours.
Fink, M.D.
Professcr of Psychiatry

Max
*

Mszp

a
A

”WJ’W‘KWVW

�</text>
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                    <text>_

movember 14, 1967

.o\‘—-—w.-.~1_.~..v..-.4,

‘

".

”

;,X Dr. Joseph 6. Bird.

-Director of £xperimﬂntal Medicine
Sterling«w1nthrap Research Institute
RensseIaer, New York 12144

‘

r~muw_yrw-¢-I&lt;-v~v&lt;ﬂ-

'

‘

Ifﬂear Joe,ﬁ

m.

'

Thank you very much-for

A

open study of

cyclazctine as

the grant~in~aid in'sunport of the
antidepressant. We are,~indeed

an

”grateful for your-continued support.of this study program.

just compTeted an additional raport concerning the
background for the recommanéation of cyciazocine as an
antidepressant. This report #111 be presented at the forth«
coming meeting of the ACRP in Puerto Rico. éEncIosed is a copy
I have

EEG

for your informatian.l

'

‘

‘

3

,

It was a great pleasure to have Drs. Rosenberg and warsha11
visit with us on Friday“ I trust that they will share with yea
.

some of our

recent experiences with naioknne. Dr. ﬁarshaI]
indicated that he wou1d like to.discuss a study.of oxypertine,
and I look forward.to meeting with him next Monday.
»

Again, our thanks.
SiﬁCerely yours,
Max

Fink,

M,D.

Professer of Psychiatry

'

MF:kp

�</text>
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                    <text>Nmnber lit ,

1967

Br. 'Ibmn M. 11:11
Missouri Institute of Psychiatry
5M0!)

metal

St. Louis,

Street

Miami

63139

Dem'mmn,

Bmlosedisadmftoopyotﬂwemportmentidepmemta

fwmfmlnmﬁxgmmﬁm. Imuldbegmtefulifym
maid review this carefully and make any necessary ametinm
mgaxdingfigumsthatmﬂdbewiate.
Inmplytoamqmstfrmm.lahmm,1ruvemmpies
ofthiedmft,euitab1ymaﬁaadmpmmdmy,mm.w1ttenbmm
for the participate at the

8mm.

Again,mybest.
Sincerely yams ,

M My ”CD.
of

£5:ch

Psychiatry

�</text>
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                    <text>mgwxmwmwmva. :11‘

,mv'lmsmurn‘vr"&gt;m—cx-.

m

“wmq‘wm'n

rpm yaw...

...

.....mx-wv-v

,‘4

.7.”

.r—wugn-Wﬂq-r

_

November

Dr. Ralph Jacobson

Associate Medical Director
Endo Laboratories. Inc.
l000 Stewart Avenue

Garden

City.

New

York l1533

Dear Dr. Jacobson:
Dr. Freedman and I are pleased to join you and your associates
on Wednesday, November 22. Unfortunately, both he and I have
commitments in the morning that would not permit us to arrive in
time for lunch and would prefer to meet about 2:00pm.

Enclosed are three copies of the summary statement of our
experiences with naloxooe as prepared for the staff presentation

Perhaps. it would be helpful if this were
available to some of your associates prior to our meeting.

on November 10.

Sincerely yours,
Fink, “.0.
Professor of Psychiatry

Max

.»

,»

Tawny-msqu

m-n

l4, l967

MF:kp

made

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                    <text>Nomnber l3 , 1967
Dr.

J. a. van-team

Rutgers -~ The State Univemity
New Bmmuidc, New Jersey
Dew Dick,

Wmtfnmiptsforthasympoeiunon

depression for the fcx'timning mm meetings. The copy
submitted is Maplete, laddng the ﬁgures. It is

suitable for discussim and Dr. Itﬂ and I will Wait
a draft suitable for publicatim at the tin: of the meetmg.
Sincerely yours ,
Pink, H.D.
Nasser of Psychiatry

Max

Mszp
cc: Dr.
Dr.

121m
11:11

�</text>
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                    <text>n

._

"Var

«av/~-

"ww1-w

‘01:

w».

a

”gm...ﬂ,.,,,...

9m

“A,” “wan—QVWWTE ”ﬁr.,hmm_--Rxl.L‘—v-~,WF ‘pm-nm—m-wxuvwcIwmow-meam

ﬁr:w'y}"&gt;:‘r“'w""}\1

November 10, 1967

Center for Professional Advancement

P. O. Box 66
Hopatcong, ﬂew Jersey 07843
Gentiemen:

I have read of the proposed conference on drug discovery
and deyeiopment in a recent issue of the Dang Inéommazion
, and am writing far a more campiete description of
:

the program, inciuding the projected dates.
'Thank you.

Sincerely yours.
Fink, M.D.
Prufessor of Psychiatry

Max

mrzkp‘

rmw \uwerov-wnuvuwwx,

V

I‘

.

,

—.

,

a m- .

.v

,

�</text>
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                    <text>9r. A‘bert,J. SilverMan

'

November 8, 1967

Professor and Chairman
Rutgers a The State University
New Brunswick. New Jersey 08903
.

‘Dear A],

NhtIe I have knawn Dr. Kiramftci for some years, our
association has been axclusively 1n the Inboratcry. We had
no medical students in St. Louis; and the residency training

,,

«WV

.
‘

was

_,

a

‘

‘

principalTy by individual lectures.

..

'

‘
_.

¢

Sincereiy yours,

‘.

4

w”-

r
h

Max

Any-q.“

—-

-H’L*;r‘

"mm-“n

I
~

..

any.»

“1.40%",

v

‘
A

,.
v

v-.,:ur.mv,»

n'nfl-lrr'.arr-"‘1—'wn&lt;

1$rwm._..rw.rmw;rv

:1"

r4

au-

arm,

«v.

V:

Fink,

M.D.

Prafessar 0f Psychiatry

«.

Mszp

�</text>
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                    <text>-

ﬂy“.

Mrr/"",.|‘:uA

1.7.x,“

..._-&lt;..-Aw.w—i

wt v“? ‘1

\er..vA-.F'm‘. :wv

--r~«,n-

‘-'~-w‘.':.‘slur.lm:

wan' .7“

November 8, l967

Dr. T. P. 5. watts
Geigy Pharmaceuticals

Ardsley.

New York

Dear Paddy,

In the interim of establishing the ketimipramine and the
cyclazocine/imipramine studies, we are in need of additional
supplies of imipramine tablets (25 mg). Would it be possible
to send us l2 bottles of Tofranil 25 mg (100 tablets per bottle)?
Thank you very much for your cooperation with Dr. Bird.
that he obtains the necessary documents for you shortly.
so that a definitive study can be undertaken.
I hope

I note that you will be in Houston at the end of the month.
I do not think that I can make this meeting, but one of my
associates, Dr. Luigi Bucci,will attend and I have asked him

to listen carefully.
My

best regards.
Sincerely yours,

:1
w-

mr'niub’

Fink, ﬂ.3.
Professor of Psychiatry

Jymrlnva'nwvvr

Max
,Wy

.&gt;

w—su-‘Wmn’ﬁx

xv.

Mszp

�</text>
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5

L

Hovomber

Dr. Leo

8, l967

Hollister

Veterans Administration Hospital
Palo Alto. California 94304

Dearvtoo,
I read your report on ST? in the latest issue of Science
with great interest. Since the first reports that chlorpromazino
ur—nwi

accentuated the clinical effects of STP. it was apparent that. if
these reports were true, then STP must be more similar to Ditran
and atropine than to LSD and moseoline. Your report clarifies the
apparent discrepancy between the pharmacological data in the press
and the statements from the FDA.

.vyrrmw-r

(if

pm

ow.

raw

WWI"

armmuvmw

cw

esoecially interested in using
and important discrimination.
YoUr report in Science notes that EEG records were done prior to
drug administration. More these repeated during the drug period?
If so, were the changes consistent with any of our reports of EEG
changes with anticholinergic and sympathomimetic hallucinogens?
Incidentally, thank you for your comments on Oxypertino.«
I
If can get some for EEG trials, I will surely lot you know
what we find.
our

I am

EEG

writing because

methods in

we

were

this difficult

Sincerely yours,
wva-ap-wmvxwya-nur-u-r-WWV

Fink, $25.9.
Professor of Psychiatry

{t‘ax
wy-vr-w-u-vw

HF : kp

m—m‘JP"

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V

mun—n.

“symmvww

——

WMMJWZVW‘mwrwnr-wn

row

'WF

November

8;

1967

Dr. Paul Kay

l5 Canterbury Road
Great Neck, new York
Dear Paul.

calendar for February l968, and find
conflict.
recess_f0r the schools in Great Neck
lo -.24. and I have planned to
in
the
February
occurs
period
take my family on a ski trip to-Swltterland. It will not be
possible for me to participate in the meeting of February l9.
a

I have

Just

Checked

The Spring

my

regret very much this inconvenience, but would be pleased
to suggest other members of the Soclety‘as,a discussant. Unfor—
tunately. I had hoped ta carry an a dialogue with Dr. Klerman and
extend your explorations into new formats for the mcetlng.
I

Please call

assistance.

me

at your convenience if
'

I can be

of

Sincerely yours,
Max

fink, ﬁ.D.

Professor of Psychiatry
ﬁF:kp

any~

�</text>
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                    <text>November

Dr. Norman E.

8, l967

Pitts

Associate Director

Chas. Pfizer a 60.. Inc.
Department of Clinical Research
Grnton, Connecticut 06340
Dear Dr.

Pitts:

‘

study of Doxepln is continuing actively and we are
additional supplies. Would you be able to send us
of
Doxepln, 50 mg (100 capsules per bottle)?
l0 bottles
The

in need of
Many

thanks!

Sincerely yours,
Fink, ﬁ.0.
Professor of Psychiatry

Max

Mfzkp

Please ship to: Dr. ﬂax Fink
Department of Psychiatry
New

5

York Medical College

East lGan Street

New

York,

New York

l0024

�</text>
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ﬁovember 8, 1967
Dr. Joseph G. Bird

Sterling Hinthrop Research Institute

Reasselaor,

New York

12144

Dear Joe,
We are continuing the present cyciazocine ~ depression
study and are in need of additionai supplies of cyc1azoc1ne
placebo. Would it be possible to provide us with an additional
ton bottles of placebo (50 tablets per bottle)?

Many

thanks!

Sincerely yours,

Fink, M.D.
Professor of Psychiatry

Max

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November

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exal’ﬂww'vr)ﬁﬂ‘u'9x--I'wl"':

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6, l967

Dr. Lino Covi

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Assistant Professor of Psychiatry
The Johns Hopkins

University School of Medicine

60l North Broadway

.

Baltimore, Maryland 2l205

Dear Dr. Covi:

It was a pleasure having you visit with us today. This is
to confirm the procedures which might be implemented subject to
the agreement concerning the protocol by your staff and Dr. Donald
Shapiro and myself.
We are equipped to undertake the
analysis of the necessary
records in 100 subjects half of whom are to receive Bilantin and
the remainder a placebo for periods of two months. he would
recommend that EEG records be obtained on two occasions prior to
drug treatment and a single record at the end of four and eight

wee

s.

We will provide the results of period
as described
analysis
in the attached report with the outputs availa
e in printed form
and in data cards.

it will be necessary that
electroencephalograph which is linear in its
output on magnetic tape up to 80 cycles. frequency oscillator, two
channel oscilloscope, and a l/2 inch FM tape recorder compatible
with the SP~300. he would like to recommend that you use Ampex
746 l/Z inch tape or its equivalent.
If such a study is of interest to you and your associates, I
would be pleased to discuss with you the additional costs of data
analysis and consultations.
To accoMplish

you have

available

this study, however,

an

,

-My

best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

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0r. RaIph Jacabsen
Associate Medicai Director ,
Ends Laboratories. Inc;"
1000 Stewart Avenue
Garden City, New York 11533

ﬂavember 3,’1967’

'

sear-Dr. Jacobsen:
Enclosed is an announcement of the presentation of the‘
naioxone’data at Metropolitan HOSPitaI on ﬂovember 10. Yen
and your associates are-weicome to attend and I hope t9 have
the opportunity to discuss-the presentation with you.

Sincereiy yours.'
‘

Prefessor of Psychiatry
Mszp

'

�</text>
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..

_,

_A

0...”,

‘nwvtw

Hovamber 3, 1967

Dr.

Fietchar

Owens

A. H. Robins Campany
i407 Cummings Drive
Richmond 20. Virginia

Dear Dr. Owens:
The initial supply of Tybatran
November
1. I want to thank you
on

capsules. 250 mg, arrived
for this supply. and for

your cooperation in obtaining a suppiy from your iocai distributar.
He was kind enough to deiiver Tybatran, 359 mg capsuies, sufficient
for the next week of the study program.
Three patients have already been in treatment siace October 26,

and two additional

patients

W".

Thank you very much

-7“.

began on ﬁavember 1.

for your couperation.
Sincereiy yours,

‘wwv,‘_n

..

qw-mww-y—‘W.

Fink, M.D.
Professcr of Psychiatry

Max
.w-rpa

"a“

..
4
w»

“rm-n”

Mszp

‘

�</text>
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                    <text>November 3, 1967

Miss Gertrude Samueis
New York Times
New

York.

New York

Bear Miss Samueis:

is

This presentation of a nave} treatment of narcotic addiction

a preliminary statemant of the

to attend.

availabie data.

You

Sincereiy yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

are weicome

�</text>
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                    <text>november 3, 1967
Mr. Henry L. Giordano

633 Indiana Avenue, N.h.
Washington, D.C. 20226

Dear Mr. Giordano:
stamp

Enclosed is an application for registry and
spacial-tax
for a marijuana permit, class 4.

This application is submitted
the suggestion of the
National Institute of Rental Health at(Dr.
Jerome Levine) and
the Chairman of this Department of Psychiatry,
Dr. Alfred M.
Freedman. Since l953 I have carried out
intensive studies of
the effects of a wide variety of psychotropic
drugs on EEG and
behavior. The present laboratory at the new York
College
is the third under my direction. This laboratory Medical
is
specially
equipped to carry out studies on the duration of action
of psycho~
active compounds. and the intar»relation of changes in brain
function and

behavior.

Recently,

we

,

have studied

narcotic

and

anti-narcotic

interest in marijuana and the availabilitycompounds.
marijuana extracts, we have made application to the National of
Institute of Mental Health for supplies for these experimental
With the present

studies in volunteer subjects.
Thank you

for your cooperation.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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~

‘

M

‘vh‘hkm

‘W W

..

M"

“W“

»

~m..“mmmmme—VWW.mvmwmwmm.wmmwm mwmmw

{I}

November

2,

1967

Dr. Joseph 6. Bird

Director, Division of Clinical Research
Steriing~winthrop Research Institute
Rensseiaer, new York 12144
Sear Joe,

of a

this

As yau know, we have carried out some preiiminary studies
new narcotic antagonist, naioxone. The EEG patterns of

compound

are different frcm cyciazocine.

data is quite similar however.

The

clinical

you or any of your associates are interested in
attending, I wouid be pleased to see you at the meeting..

If

q
My

best regards.
Sincerely yours,
Max

Fink.

M.D.

Prcfessor of Psychiatry

Hszp

“Vim“...“w‘”

�</text>
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r" vx-r- ww-xu-

’Wp‘WI-WF'HM'MV

w

ww'Wv-x-x

av»
‘T‘VF‘,‘¥ZV*I‘i‘w‘wwnllm-ww‘,w~~

-

"7.":"m‘limwww-m&gt;1.

hoVembor

l,

V7-I-‘ﬁ‘m'yn-v—Vuw-0.1.9....mr ,

n...

“a“: ,7... amp.“ ,wwwmnnquw—am

1967

‘Dr. Leon D. Hankoff

hirector, Department of Psychiatry

Queens HOSpital Center

7

'Queens General Hosoital

82~68 l64th

Jamaica,

ﬂew

Street
York

Dear Leon,

for accepting our invitation to share.
Mental
Health Clinic, your imoressions of
of
the
staff
a psychiatric satellite clinic operation. As I mentioned, I.am
interested in having observers of the Mental Health Clinic share
their experiences with my staff3.as we struggle with the develoo~
ment of a program in this Hospital. The meeting will take place
at Metropolitan Hospital, 97th,$treet’and Second Avenue, on
Wednesday,~Nohember l5, at lD:OG am. we will meet in the clinic
on the lSth floor. The meeting_will be quite informal with a
orchable attendance of twelve to fifteen staff membors;
Thank you very moon

with the

Following your request, I have asked 9r. Robert Sharoff to
with
meet
you earlier at his office on hard lSA.‘ This is one
of the psychophannaoology study units-and is dedicated to the
study of new drugs in the:treatment of addicts. He will share
with you his extensive experience in many treatment attempts~
with this population. loam taking the liberty of enclosing a
copy of the report which has Just appeared in the J.A.M.A. which.
describes our most recent experience.
-

'

time permits, 1 would be pleased to tell you of our more
work
with naloxone ~ studies that have been suspended
recent
because of a shortage of medication ~ a shortage which I hope is
temporary for this work has been most exciting.

If

'

Thank you

for your willingness to visit

With us.

’Sinoerely-yours,

'

MF:kp

Max Fink, M.B.
.Professor of Psychiatry‘

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                    <text>Nevember 20. 1967

“aw

Dr. Donald F. Kle1n

n1rector cf Research

V811iside Hosp1ta1
G1en Oaks. New York

08!? 90“.“
In requnse to your request. enc1osed 1s a 11st of‘my
pub11cat1ans. All the pub11cat1ons between 1955 and 1963
resulted {ram wcrk at H11131de Hospital In add1t1on there
‘are citat1ons 15 1953. 1964. 1965 and 1966 wh1ch are marked
1n the 11st. uh1ch are predom1naat1y the resuit of work done

at

aini
q-

W;

H111s1da Hosp1ta1

*5

1*

.

Sincere1y your3.

V5-

V

3
11“;
_

"a

3‘15."

; 3!§?'&lt;tf

7

Professar of Psychiatry

_..
,gM_~
4M—

1’"

.

«3

‘

b y
NWmM
.9

3"
2;”.‘1‘;'

'

MF:kp

“

1.139%

.,1,'

1
"91.9%,..‘45;

:2lHﬁﬂﬁ

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�</text>
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                    <text>I

wwww—ppg!

~

.

am-mwmr-mnwyu—nun—.www

'

.

vwmw‘rw-«vm&lt;

W'nw'q'

*Iovenber 1, 1957
Dr.

Carl Salmsh

ECDEJ, Paydmophannaooldgy Research

Brmh

National Institutes of Mental Health
Bethesda, Maryland

DearDr. Salman:
Thank you for your letter of October 2%. The list of studies
cmrently in progress has been markedly augmnted during the peat
few months. Enclosed are copies of research plan mporte for each
of the studies omehﬂy in progress and those that will be uhder~
taken during the next two Booths .

»

two oyolazoojm audios, the first in narcotic addiction
has been ompleted and two reports have been prepared. One has

0f the

Mean

seams Macadam during:
appeared in the Jamal”. 05 the
the past month and the second is in press in the humane Jamaal
05

first study of cyolazoome in depressive disszich. being- mleted
suit the second has
already been

orders is
planned.

The

now

The fluphehazine decorate stmiy is in progress , with the
protocol having been mdified so that after 20 cases fluphenszire
shah-triﬂe will be introduced as a omparstive drug.
We have recently begun to use the biometric laboratory form.

‘

.

to have you and Bill
13le
discretion.
I

a

would be

I look forward to seeing you
I

3.1:

(Buy

visit with us at

San Juan.

Sincerely yours ,
Mswaink, Mi).

‘

Professor of Psychiatry
_

your

�</text>
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                    <text>December 29. 1967

Subscription Department
Ha1ter J. Johnson, Inc.
111

New

Fifth

Avenue

York,

New

York 10003

Gent1emen:

that

subscriptions may have discontinued
grateful if you wou1d check your
inadvertantiy.
records and indicate the subscriptions which are either
active or inactive which are in my name at either my present
I be1ieve

address,

my

39

my

I wou1d be

Arieigh Road, Great Neck,

former address of

or 94 Lake

11

Forest, St.

New

York 11021,

Bayview Avenue, Great Neck.
Louis, Missouri 63117.

Thank you.

Sincere1y yours,

Fink, M.0.
Professor of Psychiatry

Hax

Mszp

or

New

York,

�</text>
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                    <text>{‘7'

:w-VI’v-I: .-.

7-K.

1r»

'T—m mwv'r-

-

a

.w

as «w- &lt;v w.»w~.-..V,-mv---m-we ,

~

“4“:

.

.

.—._-

rg...‘w-;;me WV» mu."

2»

.

‘1'

w

u m

war-—

December 29, 1967
Dr. Leon 0. Hankoff

Director, Department of Psychiatry

Queens Hospital Center
Queens General Hospital

82-68 l64th Street
Jamaica, New York
Dear Leon,
Your

visit to this

department was a stimulating one,

my associates and I have been encouraged to continue
our explorations in the development of a community based

and

satellite center. Please accept the

enclosed honorarium
and
token
is merely a
grossly unsatisfactory as a
fee for your services.

which

My

best wishes for the

coming

year.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp
enc.

�November 1, l967

Dr. Leon ﬂ. hankoff

Director, Department of Psychiatry

Queens hospital Center
Queens General Hospital

l64th Street

82~68

Jamaica,

New

York

Dear Leon,
Thank you very much

for accepting our invitation to share

staff at the Mental Health Clinic, your impressions of
a psychiatric satellite clinic eleItion. As I mentioned, I am
interested in having observers of the Mental Health Clinic share
their experiences with my staff, as we struggle with the develoo»

with the

this Hospital. The meeting will take place
at Metropolitan hospital. 97th Street and Second Avenue, on
wednesday, hobemher 15, at l0:00 am. We will meet in the clinic
on the lSth floor. The meeting will be quite informal with a
ment of a program in

,

probable attendance of twelve to

fifteen staff

members.

Following your request, I have asked Dr. Robert Sharoff to
meet with you earlier at his office on hard 15A. This is one
of the psychonharmacology study units and is dedicated to the
study of new drugs in the treatment of addicts. He will share
with you his extensive experience in many treatment attempts
with this population. I am taking the liberty of enclosing a
copy of the report which has just appeared in the J.A.M.A. Which
describes our most recent experience.
would be pleased to tell you of.our more
studies that have been suspended
because of.a shortage of medicatieo - a shortage which I hope is
temporary for this work has been most exciting.

If time permits,

recent

I

work with naloxone «

Thank you

for your willingness to visit with us.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry'

Max

.Mszp

'

�</text>
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                    <text>..,.

Sewn...“

.w

W

wag-WW...-

m

”mum-aw.

wwmw

V,

.

December 29. 1967

Mr. M. Kietzman

Biometrics Research
722 wast 168 Street

New

York, ﬂew York I0032

Bear Mr. Kietmaan:
Thank you very much for your letter of invitation and
the program of the Biometric Research Workshop, to be heid
February I3~IS. Whiie I wouid Iike very much to attend this
conference, I find that I have aIready accepted another
invitation to participate in a program in Europe. In the
event that I am unabie to make that trip, I wiII caII and
confirm my attendance.

Thank you once again

for your kind invitation.
Sincereiy yours;
Max

Fink, EH}.

Professor of Psychiatry

Mszp

�</text>
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                    <text>“WNW

errr mm. y-mu»..mn-r~

ammunmmw-mrv-nm-v‘v.m4”

wry-Tww'WI-i-ww..uitmﬁw‘w

'm’w—a

:m

.

.

.

ﬁrm."I-

December 29, l967

Br. Necmettin Polvan

Abuulhak Hamid Cad. 76/4 Serin Apt.

lalimhane, Istanbul

Turkey

near Gr. Polvan;
Your recent letter about the fluphenazine and butaperazine
studies was most welcome. Turan has told me of the data from the
butaperazine study and I look forward to reviewing this with him
on my next visit to St. Louis.

pleased that the concentrated flunhenazine arrived and
found
useful. This supply was specially prepared for
that you
have
we
and
usﬁ
requested a large clinical supply be made available
as soon as practicable. The laboratories in New York have agreed
to supply us with a large quantity and they are proceeaino with
production rapidly. Additional supplies will he sent as soon as
I am

it

they are produced here.

Turan has suggested that I visit Istanbul on my next trip to
Europe. I have already made plans to be in Switzerland during
the period February l0 - 24. I would like to visit Istanbul during
the last week of February, arriving February 28 or 29. I will have
a more definite itinerary late in January.
Will you be in Istanbul during
to visiting you then.
My

best wishes for

that

week?

a Prosperous and Happy

May I
New

look forward

Year!

Sincerely yours,
Fink. M.D.
Professor of Psychiatry

Max

NF :

kp

‘
-.

a.
-,.
.r
i:

ri-i.;.;;4_g;..

.n‘

o
a.
gag;

2r...
—‘

�</text>
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                    <text>December 29, 1967
Dr. Norman E. Pitts
Chas. Pfizer &amp; Co.

Groton. Connecticut 06430

Pitts:

Dear Dr.
We

are in need of additional placebo Doxepin capsules.
kindly arrange to send us ten bottles, lOO capsules

Would you

per bottle.

Thank you.

Sincerely yours,
Fink, P'1oDo
Professor of Psychiatry

MéX

HF:kp

�</text>
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                    <text>December 29, 1967
Dr. Hilos Vojtechovsky
Institute of Pharmacology
Medical Faculty of Hygiene

Charles University
Praha l0 - Vinohrady, Srobarova 50
Czechoslovakia
-

.

Dear Milos,
You

have been so kind and thoughtful in sending us the

many wonderful new stamps of Czechoslovakia.
you and on this yearaend occasion. I want to
New

was kind

take this

opportunity to wish you and your family a most
Prosperous

It

Year!

of

Happy and

I am also writing because I plan to be in Europe in
February. I would like to have an opportunity to visit
Prague. Hy plans make the last week in February available
for a visit. as I will be on route to Istanbul.

In the same post, I am writing Professor Roubicek,
suggesting that I visit his laboratory on February 26.
Would it be possible to visit with you on February 27?
Perhaps you may call him and arrange a_visit that would be
convenient for both of you.
Again,

my

best wishes for the

New

Year.

Sincerely yours,
ﬂax Fink,

”.0.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>December 29, l967
Dr. M. P. Colvin
Medical Department
Burroughs Hellcome and Co., Inc.
l Scarsdale Road
Tuckahoe, New York 10707
Dear Dr. Colvin:

are continuing our study programs with long acting
fluphenazine and have found Kemadrin to be a useful agent.
Would it be possible for you to provide us with an additional
supply of Kemadrin, 5 mg tablets. either in a bulk of 5,000
tablets or in individual canisters of 20 tablets each, as
you previously supplied?
we

My

new.

Aw"

.&lt;

New

Year!

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
A.

”w.”

best wishes for the

Mszp

�</text>
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                    <text>m

nan-rm wank? Xam'rwrmv-v-u

- v.7“ (rm-um

"r

'vysu;.vndv'.;.

or-

.,..

arms—m

«W

ww-«rqu-rx

December 29. l967
Dr. S. Clyde Strickland

ﬁerck Sharp and ﬁohme
west Point, Pennsylvania l9486
Bear Clyde.
As I described to you, we are in the midst of the evaluation
of the long acting fluphenazine, fluphenazine decanoate and enanthate.
It is necessary to give the patients an antiparkinson drug concurrently.
he have been in the habit of using procyclidine.

Recently. one of my associates felt that Cogentin might be
useful and we have made such a trial with some success. I
would like to extend this and I am writing to ask if you would
make available to us a trial supply of 2,000 tablets, 2 mg each?
more

A

copy of the protocol under which

is enclosed for your information.
Many

thanks.

My

this study is carried out

best wishes for the

new Year!

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

ﬁszp
cc:

Mr.

Tolkoff

2 ¢

,v

u .,- m.

.,,.

.‘

gym

�</text>
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                  <elementText elementTextId="102381">
                    <text>_‘m.,.:,,..‘.. .u, u...,.

.- ,

.

v...»

, .
-m. 7.2
m“u. «muwv-‘Tsklv'llvzr$~,&lt;w-:K,xr
~

,

,
-.,.
"qu,“ 7.. ‘mnil'
-

,

x- , .ﬁA ,.-. g we...» .mw KWH‘A'K-mv
.«

I»

7,

.~m .-.y-.w.UL

.
v“. yr“:
«WV-«m.&lt;- ,wn,‘ "v.“m-.-y.-v-mvmn,
“7. (4r"".
-.|
_

v

.

December-29, 1967
Dr. Joseph G. Bird

Ster1ing~winthrop Research
Rensse1aer, New York 12144

Institute

Dear Joe,
As I have written, we
are now comp1eting the co11ection
6f data in the Open cyc1azocine study.
However, there are a
number of patients who wi11 continue on cyc1azocine
the
next two months and I need a sma11 additiona1 supp1y during
of

cyc1azocine p1acebo and active. Wou1d you be kind enough
to send us 1,000 - 0.25 mg cyc1azocine p1acebo.and an equa1
amount of active cyc1azocine?
My

best regards.
Sincere1y yours,‘
Max

Fink,

M.D.

Professor of Psychiatry

Mszp

“Ange“.

~,.w

.‘v

y':--

v

«a

‘

�</text>
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                    <text>December 29, l967
Dr. Turan

M.

Itil

Missouri Institute of Psychiatry
5400 Arsenal Street
St. Louis, Missouri 63l39
Dear Turan,

Enclosed are a few abstracts which have been submitted.
For the Society of Biological'Fsychiatry, I took your
suggestion and have sent the fenfluramine amobarbital data.
In addition I thought they would be interested in the phantastica
classification as well.
—

it

would be
I have never been to Honolulu and thought
a good Opportunity to visit there oy attending the American
Therapeutic Society. I have asked Jovan to begin writing
up a report of the cyclozocine depression data and this should

be done within the next month. It
would like to present in Honolulu.

is this material that

I

Some time ago I was asked to look at a compound,
oxypertine, because this will be a good test of the EEG
programs. I would like to do this in volunteers, however.
it may be helpful to me if you would be willing to run a few
of your patients and perhaps to do so with pentothal activation.
Enclosed is a proposed protocol. Please review this and let
A

me

have your comments.
My

best regards.

.

‘Sincerely yours.

Fink, M.D.
Professor of Psychiatry

Max

Mszp

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                    <text>December 29, l967
Mr. Peter M. Irwin
315 w. 70th Street, #GJ
New York, New York l0023

Dear Hr. Irwin:
I am pleased to indicate that the erartment of Psychiatry
will extend an appointment as research assistant, effective
January l5, l968. In this program you will be responsible for
your assignments to me. The principal program in which you will
be working is in the evaluation of the treatment of narcotic
addicts, a program supported both by the USPHS and the New York
State Narcotic Commission. You will be asked to work 40 hours
per week and to assist in the data collection and data analysis
of this progrmn.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>December 29, l967
Br. J. Roubicek
Psychiatric Research Institute

Prague, Czechoslovakia
Dear Dr. Roubicek:
"r
v
V

r.

vw

_r,,-..,-:—ny.w.o

last visit to our laboratories, we discussed the
of
possibility your participation in the study programs of this
During your

department during l968.

to be in Europe in February and would like to arrange
week of the month.
I would like to arrive on Sunday evening, February 25 and visit
with you on Monday, February 26. This is a tentative date, for
I may be detained by one or two days, but I should know this late
in January.
a

I plan

visit to your laboratories during the last

it

would
be possible to visit with you at
have the opportunity to meet with your
Dr. Matousek in particular.

like to

New

In the meanwhile.

Year:

my

best wishes for

that time?
associates,

Fink, M.D.
Professor of Psychiatry

c

run-"1

v:
v.5

Mszp

and

a Prosperous and Happy

Sincerely yours,
Max

I would

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December 28, l967
Dr. Solomon Snyder
Department of Pharmacology
Johns Hopkins Medical School
725 N. Wolfe Street
Baltimore. Maryland 2l205
Dear Dr. Snyder:

presentation at the recent
As
soon
of
the
as your report is available,
Acnp.
meetings
I would appreciate receiving a copy.
I very much enjoyed your

Enclosed are our reprints which you requested, describing

our experiences with anticholinergic hallucinogens.
Thank you

for your interest.
Sincerely yours,

&lt;

Mun-w;

Fink, M.D.
Professor of Psychiatry

Max

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December 28, l967

._,,V,,._m,,...,._.,,

Dr. Herman C. B. Denber

3”,,

Director of Psychiatric Research

Manhattan State Hospital
Ward's Island

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York,

New

York 10035

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Dear Hy,

Enclosed is an abstract for the forthcoming meeting of
the Psychiatric Research Society (GWON) to be held on March 22.
Following your recommendation of papers describing clinical
and basic science correlation, I am pleased to recommend the
report "Heroin - Challenges in the Evaluation of the Treatment
of Opiate Dependence.”

'ﬂﬁlwrimrwe.‘r'-vwv-'.I-»«a—v.,,.”..

Incidentally, Jonathan
on February l0.

IWWW'KW‘I'.‘IMJ~W-'w&gt;m”wmrwv,”

,

Switzerland
joining us?
My

Mum-v

r

best wishes for the

and I are looking to leaving for
Would you and Michel consider
New

Year.

Sincerely yours,

waiver—Mum.”

Irv—n

'

Fink, 24.0.
Professor of Psychiatry

Max

Vim-w.

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Ivrnw'lwn‘nnv‘ 'y-wmu

December 28, l967
Dr. Roger Meyer

National Institute of Mental Health
Bethesda, Maryland
Dear Roger,

It

of you to visitzny laboratory and I was
have
the
to
pleased
opportunity to discuss our research
was kind

programs.

In the interim, until the naloxone paper is completed.
taking the opportunity to send you a draft of a chapter
in a forthcoming volume on the treatment of narcotic addiction.
This chapter reviews our present position with regard to
narcotic antagonists in the treatment of opiate dependent.
I am

my

best wishes for

a Happy and Active New Year.

Sincerely yours,
Max

Fink. ﬂ.D.

Professor of Psychiatry

Hszp

�</text>
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                    <text>.

.wmwnvmvw

5.1-.-

‘

4,

I, 3,” ‘ 110'?” ., u.” ”Lyman",

thrﬂmmg

.grn-u..r,.r.‘..., W 1. "a“... 7..“ Hymn—mu

W.v.‘gmn

L-w-r;r'n:waw,-‘~yh.w

ww-

,

.

,

_

wu.‘

v

"Hunt-IT;

December 28. l967
Dr. Jerome Levine
Psychophanmacology Research Branch

NIHH

Bethesda, Maryland
Dear

Jerry,
I

very much enjoyed our discussion of our

in San Juan.

common

problems

On my return to New York, I received a letter from the
Bureau of Narcotics suggesting that the marijuana license which
I requested would be forthcoming, just as soon as I complied

with the regulations of

New

York

State.

The

letter indicated

had to obtain approval by State authorities for such
that
research. Being a good citizen, I have complied with this re—
quest and have written for information regarding the necessary
procedure to be followed.
I now

recently completed a chapter for a volume on the
treatment of narcotic addiction and I am taking the liberty of
enclosing this report for your information.
He

have

Hay I

Healthy

take this opportunity to wish you

New

Year.

1'

_‘_.

gun“;

..

A
'

-wm~

a most Manny and

—-vv,—,.n,v:,-

Sincerely yours,

'Y-rv‘:7—,-z

'vu

‘5.
1:"
ZWM’F-‘W

Fink, M.D.
Professor of Psychiatry

Max
«.wn‘raﬂ'v‘

..

«1—,

MFtkp

«v:-

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.

Way-1,...

mﬂf'r‘)

:wqunvw;

2W'vr'II—Il

~Mqr

-u

EHC.

-.{,_f-.:

�</text>
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”‘wm—y--.w‘..

m~.——~.

"‘-'.Im"fmwl—rm.

December 28, l967
Dr. Werner P. Koella

Senior Scientist

for Experimental Biology
Shrewsbury, Massachusetts Ol545
The Worcester Foundation

Dear Werner,

Enclosed are two abstracts for your consideration for the
forthcoming meeting for the Society of Biological Psychiatry.

report entitled “EEG Patterns Associated with Minimal
Alterations in the State of Consciousness" represents a detailed
quantitative assessment of the changes in scalp recorded EEG
The

in human subjects receiving minimal doses.of sedative and
stimulant drugs. The ability to differentiate the minimal changes
associated with these drugs suggests, that despite the general
misconception, sufficient data does pierce the scalp in man to
be of value in identifying small changes in consciousness as a
result of drugs.
are also submitting a second abstract, entitled “EEG and
Behavioral Relations of Phantastica in Man” for your consideration.
So much of the present interest in sleep and dreams is related to
the identification of the dream state with hallucinations in man.
The analysis of the EEG and behavioral changes with a
variety of
hallucinogens and our recent classification of this subgroup of
We

‘

psychoactive compounds
theme of the meeting.
May I

productive
My

may

contribute materially to the central

take this opportunity to wish you

New

Year.

a most happy and

best personal regards.
Sincerely yours,
Max

Fink,

M.D.

Professor of Psychiatry

MF:kp

�</text>
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                    <text>.uu-u.—...umnn

y.‘r n

w

'7’,“ mm

5.-mm awn-i'h-vn- mny

.

-

,

.

,

-v.w. '- .7

.

mummy-:11v-wvw

M

rv-w—wwr-w-

a. r’uwm'vvir'vm‘nnwhurnﬁmﬁ- r—m-u
.‘

m; ~ w

-

v-vn-n-w‘w-

December 28. l967

8r. Chris J.

D.

Simpson Memorial

Zarafonetis

Institute

University of Michigan

Ann

Arbor, Michigan 43l04

Dear 3r. Zarafonetis:

Enclosed is an abstract ”Clinical Antidepressant Activity
of the narcotic Antagonist, chlazocine" for your consideration
for the forthcoming meetings of the American Therapeutic Society.
If this presentation is accepted, I will plan to present our

observations.
He

would

prefer presenting this data at the

or the first day in San Francisco since
at the Society of Eiological Psychiatry
Thank you

Honolulu Session,

I have another connittment
on June 14, in Washington,

for your consideration.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mszp
EDC.

0.6.

’K’M‘n-w

v-w—u

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“W'N‘Jmiwmmﬁnm-wurawn-r-

.mw-

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A

December 28, l967
Dr. Charles E. Marshall

Associate Director of

Clinical Research

ninthrop Laboratories

90 Park Avenue
New York, New York l00l6
Dear Dr. Marshall:

Enclosed is a draft copy of a proposed study of oxypertine.
\After reviewing the available literature and discussing the
clinical data with Dr. Hollister, my associates and I would
like to recommend an EEG study. It is our belief, that such
a study will provide data not otherwise available, which may
be most useful in identifying the target populations for this
psychoactive compound.
The

new York Medical Colleoe will be
lose. I
undertake such a study about harch

facilities at the

l,
available to
of
the
University
associates
at
of
my
have
the
assurance
also
when
Missouri who are willing to carry out parallel studies,
they are necessary.

In addition, we would like to consider a clinical study
the
in
population of the Mental Health Clinic, as soon as we
have detennined the EEG profile and made some recommendations
based upon that experience. In that study, we would like to
carry out a procedure similar to that followed in the clinical
evaluation of cyclazocine as an antidepressant.
I would be grateful for your comments. In the interim,
please accept my best wishes for a Prosperous and Happy hen
Year.

Sincerely yours,
Fink, M.0.
Professor of Psychiatry

Max

HF:kp

�</text>
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                    <text>v...

‘

'4'”mwm'yvr,~&lt;—rmv&lt;-wc'

arm-w

December 20, 1967
Dr.

Julian J.

Lasky

Executive Secretary
Clinical Projects Research Review Committee
National Institute of Mental Health
5454 Wisconsin Avenue
Chevy Chase, Maryland 20203
Dear Jack,

writing with regard to our application for
“Theoretical, Clinical Studies of Convulsive Therapy.“
I am

(MH-lSSGl—Ol).

Since a number of the reprints are no longer available
file copies, I have arranged for xerox copies to
be made. Enclosed are five units which include representative

except for

reports related to
My

my

studies of the convulsive therapy process.

best wishes for

a Happy New Year.

Sincerely yours.
Fink, M.D.
Professor of Psychiatry

Max

Mszp
P.S.

I am also enclosing a reprint of a report
who is working with me on this project.

of Dr. Abrams.

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