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                    <text>April

3,

1967

Dr. Antonio Bottino

Assistant Director (Acting)
Aftercare Clinic
State of New York
Department of Mental Hygiene
39 East 17th Street
,

New

York,

New

York 10003

Dear Dr. Bottino:
Your

letter inquiring about referrals for medical

super-

vision for patients discharged from your clinic has been referred
to me. for reply. At the present time , negotiations regarding
this specific problem" are underway between representatives of the
Department of Mental Hygiene and this Department. Until those
negotiations are completed, it would be advisable that the present
arrangements remain unchanged.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF2kp

pt

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                    <text>April
Miss
.

3

, 1967

Phyllis Karliner

Laura Scales House
Smith College
Northampton, Massachusetts 01060
_

Dear Miss Karliner:

I have discussed your request for summer employment
with different members of the staff and can give you a mixed
answer. Your request for a clinical assignment may be fulfilled 9
but I cannot do sowith assurance now. If you are willing
to
accept either a clinical or a academic (non-clirﬁcal) assignment, I am prepared to recommend your appointmnt during the
summer period, effective July 1.
established college salary which

New

The

is

If this is satisfactory, call

York and

I will

Thank you

salary will

be

the

approximately $60 a week.

me when

you are next in

the necessary arrangements.
for thinking of us.
make

Sincerely yours ,
Max

ka

’ M. D C

Professor of Psychiatry
!

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                    <text>June 29, 1967

m. Stanley Yollee, Director
National Institutes of Mental Health
»

Bethesda, Maryland

7

-

Dear 'Dr. Yolles:

report this morning of "A drug more
special interest to me because the data
potent
the piperidyl»
likely that 3?? is one ofJE—BSE.’
presented Was it very
Wee
JB~318
JB—329
or
(Ditran),
benziletes, probably
been
have
and
decade
thm
a
s have been studied for mm
New York Time
than LSD" was of

The

'

in Milwaukee.
'Ihe principal reason for omcludmg that these compounds
the subjects
may be of this class is the clinical description that confusion
excitement,
mania?
experieme a state characterized by
and hallucimtions , misting for days; and that they exhibit
and blurred vision. The
dilated pupils, rapid pulse, dryNewmouth
Times is the exaggeration
York
most witical stetenent in the
of the; psychotic state by ohlozvmzine.
In studies both at Hillside lbspitel and at the Miami
in the Em
Institute of Psychiatry, I have been interested
some years ,
For
.
effects of a. wide Variety of hallucimggens
when
the
my associates and I have jokingly indicated that
foumi
would
be
to
giperidybbenzilatee hit the streets, they

produced by Lakeside Laboratories
.

‘

be mob

more"

potent and

much
The.

LSD, EMT and

differences between the antiand the smethmnﬂmtios are clearly
the liberty
defined by EEG and behavioral criteria. I am taking
1967 from
196C:
and
one
of enclosing; two mports - one from
studies.
vmioh describe the essential parts of these

other smatmmimtics.
'cholinergic halluoixwgene
-

more dangerous than

For practical pxmpoeee, the most important fact is that
(TEA) is a very
an experilmntal conmound, tendiydmamimcrin
the clinical symptoms induced by
potent nntegmiet modifying
90%
of the psychotwimticeractivity.
these companies to 80 ~
studies frm the Lakeside
is available for experimental
M
Laboratories, and I have a supply which has been available to
me mder an IND filed about two years ago.

.

Linn;-

3:“

‘

ﬁ.~.«:.o.-.~:;_;

easnzxeeezaly

�i
mzw‘rfu‘m‘

;rmw.¢~wqm‘

Dr. Yolles

June 29, 1967

«2—

-

7.“.

alerted our staff to the possibility that patients
with
in
acute psyclntic episodes exogenously produced
my com
md will try to modify these states by TEA. Perhaps , if a
supply of 31'? could be made available to us we muld try “to
find volunteers and detarmina specifically whether 31‘? is of
the am class as the piperidyl-benzilates and if , indeed, the
We

&lt;

»
,
-

yum-rm‘am-IWWM;

~
A.

u

have

psychotic state

is mapmaive to

TEA.

Incidentally these studies have been supported largely by
the psychophamaeology Study Cmter of HIM?! under a variety of
study grunts.

Sincemly yours ,
Fink, 24.1).
Professor of Psychiatry

Max

MF:kp
~

.5,

v‘.-:“g.g"j‘-

,
.‘

‘waﬂr

-..u1z:.

shaman-or

74:1-mnnm.ﬂw/

w
a.

.

M.

.,

w

-,
_

v

ll“.

i
mm);

A'Liistﬂt'kiihn'ﬁdr«

u—A

ura-

paw-xmmrvsv

:w

V

�</text>
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                    <text>J1me
Db. Joseph Bird

-‘

New

York 12141}

1967

7

t

Sterling-Wintm Research Institute

Renaeelaer,

29,

»

-

Dear Joe,

Wise

Sepamtely I am wading; you the
of the active
inactive owes" of the cycle’zocine trials fm 8~—1~66 to
3~31~67 at Metropolitan Hospital. There is little additional
infanmtion available. I hope that these are useful
the records
I have arranged .ﬂmt these were "owned?
by two resident physicians end agreed to
them at
and

‘

m
mate
review took 60m.

,_

_

$5.00 an how. The

-

-

It would be met

helpful

if we

eould wnpeﬁsate these
mule? ask that Sterling»;

wen

for this reason I
indirectly
Winthrop make available ’a sum of $300.00; to Psychopharmeology
Services, Inc; and seem to we at the New York Medical College.
This consulting; fim will ”in turn compensate the residents.
I look forward to seeing you next mmday. My best
and

‘

mgams.

,

.L

'

’
.

Simly yom ,
Fink ,
t
m
Professor of Pathiatr-y
‘

.

:51”sz
-

:‘
.

‘
:—

A-vrmrr"

my

—~

-&gt;

"um-Wyn

-'

mummw-f-r'

;

MuD

l

'

�</text>
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              <elementText elementTextId="28303">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                    <text>mmwm-an'ww’

.m.

-.~_.;A

June 29, 1967
Donald B. Cheetham,

Mb.

Research Associate

Jr.

Clinical Investigation Department
Smith Kline

8

French Laboratories

Street
Philadelphia, Pennsylvania 19101
1500 Spring Garden

Dear Don,

will be able to begin the additional data analyses
suggested next week, as the data cards were Shipped from
St. Louis to NEW Ybrk on June 27. As soon as the preliminary
runs are done, we will call Mike Free.
we

Thank you

for the

memnxnmhnn for my

recent visit. I

have assigned this fee to the Psychopharnacology Services, Inc.
(IRS #ll~2133166). I would appreciate the grant for the studies
of the EEG effects of amobarbital and dextroamphetamine in
volunteers be addressed to the same fand and sent to my office

at

East 102nd Stree ,

5

my

New

Ybrk City 10029.

best regards.
Sincerely yours;
Fink, 31.13.
Professor of Psychiatry

Max
MFﬂq&gt;

»

‘umuﬂ4-.- wwx.rnuwv.v-rmuwv,

"my .

�</text>
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                    <text>June 28, 1957
Dr. Thren M.

Itil

Missouri Institute of Psychiatry
SMOO Arsenal Street
St. Louis, Miesouri63139
.

Dear Turen,

of the anti~anxiety drug protocol relating
to domepin, and a carbon of the letter which I recently sent to
Dean Clyde. You will note that I sent the latest CDT report and
Enclosed

is a

copy

earlier memos regarding

to Dean.
Dr. Cremata called me today to state that the parenteral
form.of doxepin was not yet available and that the protocol will
be filed with the FDA excepting section three on page three and
including the first line of page u. He believes that the parenteral
fcmm will be available soon and would like a revised EEG protocol
from us. If you would like to carry out this
portion of the study,
some

item analyses

would you make up a suggested

protocol.

Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

enc .

�</text>
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                  <elementText elementTextId="105487">
                    <text>V,

v‘.‘

rm,”

‘vw'v'

-74.:

vww-pwxw—w-y-y-v“1. -.v,,

.« "\

,,. . «m- .,

.,.._.

t

_.,,

_

.,

‘

,vw

«hm, , ..

....

V,

June 28, 1967
Mrs. Ellen Grass

Grass Instnxmnts Co.

Quimy, Imsachuseﬂs 02159
Dear

Ellery,

equiporder for additional
Wt
twelve
have
oscillogmphs
mquasted
will new that

In mufﬁn-ting our

BEG

ment, you
oacillographs should be inserted
and two moles.
console
the oﬂmer eight in the
794i
and
polygraph
in the
“IANPHO eonsole, with om inch spacing between ten units.
we
Four of “the

With regard

to the comet electrode mlder. the nwreric

system which we nae

7

mloaed.

is indicated on the

hand sketch which

is

.

Sepmtely, I am sending a letter to Mr. Danny regarding
our under for paper, and ymahculd have already received the
order for otmr m; supplies.
Many thanks for yam: cooperaticn.
'

7

Sincerely yams ,
Fink, Md).
Professor of Psychiatry

Mm:

Mszp

‘

�</text>
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                    <text>June 28, 1957

;
va'

1‘

\.

,mr'mram

1"...

mum.

Stefan Began
Senior Research Associate

Mr.

Departrmt of Medical Investigation

Ibffmnn-La Roche Inc.
Mrtley, New Jersey 07110
Dear Mr. Hogan:

first supply of Librium
are using this as the standard in the treatmnt of
anxiety. A copy of the present protocol is enclosed for your
infatuation.
since

We

have already gone through ﬂue

we

it

Would
be possible to provide us with an additional
supply of chloxdiazepoxide, active, 25 mg capsules to continue
this study?
Many

thanks .
Sincerely yours,

1-1

.

a
(mm-

Fink, NJ).
Professor of Psychiatry

Max

‘w

HIV-V"

mp;

1r;

."A;':‘

MF:kp

�</text>
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                <text>1967 </text>
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              <elementText elementTextId="28338">
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          <element elementId="48">
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              <elementText elementTextId="28343">
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                    <text>June 27 , 1957
Dr. Joseph» Bird

h

'

.Sterlingmintrmap Research
Reneeelaer, New Yark 1.21M

Inetimte

..

Deer Joe ,
1

I

should like ta report on my reeent presentation of
the
cyclazocine—depreseim data to the ECDEU investigators in
Montreal. The mter’ial was presented at e
on enti~
depressant drugs and me than 30 investigating team were

mime

‘

represented.

.
.

CW

Since the only other optimistic name were
about
a report fmn Perle *on chloxﬁmiprenine and referencee jto
mltiple EC}: (Blachly g3; all, University of Oregon), mch
interest was
The. beet mggeetion was male
mm
by Dr]. Cole who indicated a7 willingness 1:0 use cyclamcine

em

,

_

:

mm.

in the present NDIH depmasim etudy program Eight mspitale
are studying standard entidepeeeeent drugs and cycle-moire
may be 'intmduced in the mement failures. The study is

,Lcentrolled by Dr. Raskin of the Peycmphmaacolqw Study

?

"Bremh, NW. The units most likely to be interested are
Dr. Cole/DiMaecio at Boston State; and Dr. Tyce at Rochester
(Mirme'ota) State. But Dr. Reskin indicated a willingness
to
call a meeting of the investigators later this summer am the
‘invee‘tigatere weld be pelled.
.

a

.

-.

Othfn"

j

units which expressed an interest and dealt! test}
are:

~"musicalememe

,

Dre. H. Let-mm and Bay,
Dr. A. Kmrland, ﬂexing

Manual.

Ii

'

-

We State Hospital,

Dr. Dmmld

next

ﬂesh, Hillside Hespital

'

,

I mum be pleeeed to ﬁlms; the text ates-e1: our visit

May.

.

'3le we

,

Fink, 14.9.5:
Professor of Psyclﬁatxy

Max

MF:kp

,

�</text>
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          <element elementId="40">
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              <elementText elementTextId="28352">
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              <elementText elementTextId="28353">
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                  <elementText elementTextId="105489">
                    <text>June 27 , 1987
Br. Arthur J. Lunny
Chart Paper Sales
Grass Instruments
Quincy, Massachusetts 02169
Dear Mr. Lonny:

for

will be receiving an order
following the teleprxme quotation
copy of the order is enclosed so that you

h the regular channels you

100 packs

of

EEG 30~8"-WROR

of $3.25 per pack.
can anticipate it.

A

Because of storwe problems , I would be grateful if you
would ship us 25 packs and holding the reminder until notified
by this office. Would you bill us for the total amount imnediately,
since that would be easier than billing at other times.

I have rarily used imprinted paper, but perhaps for this
new Department, it would be helpful using as small a type as is
reasonable. I would like to have the paper imprinted on a single
line as follows:
EEG

and iiuman Psychopharmoology

~

Department of Psychiatry
me

appreciate your settling the
as soon as practicable.

first

I

would

NY

.

shipment of 25 packs

Sincerely yours ,

Wm.

M"

.,,,

VIM-w...

Fink, M.D.
Professor of Psychiatry

...V

Max

..

,

wm-4mﬁyvef-(¢.w.qwf

MF:kp

Medical College

before hand, I would be

sanple of the type could be sent to
pleased. If not, go ahead.

If a

~—

�</text>
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                    <text>7mm...“

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June 26 , 1967

w,a1'w"f(wm’1—'S

Dr. Dean

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J.

Clyda

University of Mimi

P. 0. Box 8293
Coral. Gables 148, Florida

DaarDean,

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gratefulformintmst.
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clinicalmportafthedatagasmllastmsmries
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oftmimanalysis
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Pink,

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CDT Report v: 5-27~67
Mums 3-9~66, 3-10-66

cc: Dr.

WM. Itil

I‘LD.

of Psydﬁatry

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                    <text>“‘i
-l,

A

‘7va:

w

(~7f'n—-I:v,-‘Wrw&lt;uwi"fu-W

Juno 26 , 1967
Dr. Jonathan

0.,Cols, Chief,

Balm Building

Wisomsin Avenue
10cm

514514

Room

Chevy Chase,

PRB

,

.

mum
‘

Dear Jmathan,

It was with-sadmss and regret.
mam:

that I mceivodthe ammunce-

that yourm leaving NM. Since its inception as the

Psychoplurmacology Service Center, your leadership, tolerance
and patience has fostemd rmch of the psychopharmcology research

of the nation

«

indeed,

You mow, because

much

I

its biological

of

research in psychiatry.

earlier occasions

W.

have on

@cpmssed my

gratitude, that the research
at Hillside Hospital in' ECT,
EEG and in psycmtive
maimed
such of their support fm
We
PSC. The Missomo'. Institute of Psychiatry was also successfully
lamched primarily because

its programs in EEG

the,

of”

flexibility of Federal support,

trials-and chronic
schizopmenm were all basod on PSC Support. Indeed, we even
came to you for help in marching, am} were gratsful for your

and

assistance.

analysis,
_

r

new drug

'

'

.

Perms my greatest personal debt
NIMH

wasPin the Opportunity to
the Camnittee few Clinical Drug Evaluatim. It was
hemttatlsensedyourlesdershipbest~andlhthtthat
Committee will keenly fool the loss mment in your decision.

serve

on

So, for the record, pleass accepts}: personal thanks for
yew many considerations and your faith in the study programs
at Hillside (1956-62) and the Missouri Institute of Psychiatry
(1962-66) without which, the programs would lave failed.
Also, my very very best wishes for a successful career in Boston for if anyone can We changes in Samoan/ices, perhaps you can.
—-

.

My

best personal regards.
Sincerély yours ,

,

1‘41”}qu

7‘

cc: Dr. S. Yolles

sax Fink, 2w.
Professor of Psychiawy

�</text>
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                    <text>June 26, 1967
Dr. Bummn C. Schiele

Professor of Psychiatry
Department of Psychiatry 8 Neurology
Univemity of Minnesota Medical School

W113, Mﬁnmsota 55%5
Dear Burt,

mat know I enjoyed the recollections of your Eastm
tourverymoh; andanwritingtoaskﬂmtympoxmitmeto
homo»: your Istanbul slides so that I might have a few from
Bakfrkfy copied. I will return the set pranptly.
You

A

a
Many

thanks.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                  <elementText elementTextId="105490">
                    <text>r“

-

"r“ '

»

~

7’

-

«w:

&gt;

-- ma

mama”. I'm-u mug-em" WM“- ,.

,.

c.‘_w ,m mun

.u

I"

Vim-mu.

Far-arm.”

~.-_ V..r..,m,...-....—..W.1ww..—~mv5mm...”.77.,“

w...

_.r,

m

Wm.

“Wu“_..,.,.‘M.V.Mwinwnawh.7-..,......M,..,Ah._,.,..,w.-.....

June 26 , 1967
Box 1

Psychiatric

News

Street,

1700 18th

NM.
20009
D.C.
Washirgtm,
Gentlemen

:

is of special interest to me , not
for myself, but for associates who are interested in developing
their om research facilities in New York. As you may know,
Your advertisement

I was responsible for developing the research study program
at Hillside Hospital, 195%62, and for establishing the
research facilities in St. Louis, the Missouri Institute of
a

Psychiatry.

During this time, I have become associated and acquainted
with a nmnber of physicians who may be very suitable for this

position. Iroanbeofanyhelpinmakingsuchamcamnenda~
tion, please call on me.
Sincerely yours ,
Fink, M.D.
Proﬁesscr of Psychiatry

Max

Hszp

�</text>
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                    <text>m. 21,
Dr.’ Richard P.

mite

1987

:
.

Associate Professor of Pharmoology

Unimsity of Temssae
DBW'C of PWIOgy

The

Mmzphia, Tennessee 38103“

Dear Dick,

I have visited Sterling~wixrthmp and me
negotiations for the ewion of our study programs in
I have also called Dr. Cole
cyclazocine am now in
in Washington and ho has no objection to my writing a letter
mhhnmquesting to use somafmm funds fmozmoyolazooine
study pmject,’ if the: negotiations with SterlingMinthrop fall
Dr. Madman and

Wgh.

'

‘

hm

written to Dr. Cole, and have; submitted all the
necessary data sheets to Sterling-MW. I am optimistic
that we will most likely be able to support the smaller budget
and probably the larger budget I will have to give maximowinthrop mtil July 1 for Miranmandhopothat Iwillhavo
cm from NM before then.
In the interim, please accept the oomtltation fee for
recent
visit. My best mgazds.
yomr'
x

'

ms.

,

'

.

Sincerely yours ,
Fink, M.D.
Professor of Psydxiatrv

Max

�</text>
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                    <text>.

e

June 23;, 1967

aner
Autonomics Divioion
Dr. A.

‘

,

Natioxml Physical Laboratory
Teddington, Middleeex

DearDr'.
.

I

8mm

have read. your cm'rioulm vitae with intemet.
I first developed my quantitative EEG etudy

Some

ago when

yeam
, an

experimntel hemophyeiol lot was associated with me and this
relationship wee mtmally very eatiefeotm. Subsequently, he
went on to animal work and hesbeenpmduot‘ive. Since then, ‘I
have usually had physician electroencephalogram mm with me.
but would be pleased to
en applioetion from you, if
the study programs are of interest.

'thein

G

laboratory consists of clinical. research unite in a
general hospital with 50 impatient beds dedicated to
thempy eewoh and a developing study unit in. the outpatient
'Ihe

Woo-

For ewe years as the encloeed

reprints will indioate, I have
EEG mmeeion of a wide variety
of psychophemaoologioal agents , and the relation of these changes
to behavior. The patiente- in the study units are the subjects; and

been

particularly interested in the
.

.

generally have two EEG labomtorieo nmning on a full time basis.
of the work of thepast few years has been in the technical
aspects of the enalysie of the EB; and we have. devoteo‘moh study
to digital mutter methods. In Miami, the laboratory was
equipped with an IE)! 17104620, and in New York we have. recently
inetelled an IBM-1800. This machine" is “looted emlueively to,
EEG analysis
we

Much

I

.

-.

he of m, we are pertioulerly fooueeed on the problem of
narcotic addiction
and have specific interest in narcotics ,
narcotic: antagonists, alooMl, and hallucinogens. Imidentally,
I do not have any facilities for
audios and while facilities
exist in the Department, I emnot inelined to enoourege such
exploration, since I have generally found that, the animal date is
of limited application to the studies in volmteem. or the mentally
1113 which mpmsent my populations; of ohoice.

m1

‘

’

‘

,

.

�”W

”wwur,»

Men—3...

Dr.

j

Bummer

'

,

June 21,1967

‘

'

'

~—2-

Mae Studies are in the Department of Psychiatry at the
New York Medical College - independent mica]. school
-,
120 studentsineaohclass.
mining program in psychiatry with ﬂames averaging 16 to 18
each year. The clinioal facilities are at a city. hospital and a
new
Wt}: mental health center is being built for occupancy
early in 1969. The m center does provide clinical research
facilities for these; gamma.
I am mlosing‘som reports ftm this lalmtory which
Will give you anidea of the work to date. After reading theae,
if a positicm in this Departamnt interests yeti, I would be glad
to call or write to some of your mferemes. Incidentally,

MWMamyhr-ge.
»

.

.

mm to the Uni-ted
.

«would

you plea“; indioate when you desire

to

Sincerely yours: ,
Max

Fink,

94.33.

'

meessor of. Psychiatry

t

MF:@

nah/‘9'

v:
a.
raw

v-w.

,,

's‘yﬁamglq'm'nh”

“
.

A

54

-

.

&gt;

�</text>
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.,..7

m...

ﬁn,” ,..m.,.5—~m«

WW._—».~-.-.--5.09m...

.

..— .1 .-

“$0,“.-.
v

-

‘wm

n-‘1'-V'v"'V7i"\"'i_“

v

'

"- "”7""
‘

'

J1me 21, 1987

Dr. Zdenek Votava

Professor of Pharmacology
Medical Research Associate IV
Galesbtmg State Research Hospital
Galesbm‘g, Illinois Sltml
Dear Dr. Votava:

Despite its hectic ham, my associates and I were
grateful for yum visit with
us. Even though them are
some differences mgazdmg 01m views of EEG anddbehavior,

Ithinkthat

ftmdannntallymagmemdwmmenmsay
that bmin function
and its changes are critical to behavior.
I muld be pleased
for your visit with ua.
My

if you would

accept

this

Wan

best regards .
Sincerely yours ,
Max

Fink, MD.

Profeamr of Psychiatry

Wzkp

�</text>
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                    <text>why—rpm

.7

June 20, 1967
Mr. Melvyn Fawn-nan

1105 Winthrop

Bmoklyn 12,

Street

New

York

Dear Mr. Feuemm:
Thank you for yum? application. At the present time my
do not find the specific job which muld best

associates

utilize your talents. waver, I muld like to msem the
privilege of holding your application on file and will contact
you as soon as we are able.
Sincerely ycum ,
Fink, M.D.
Professor of Psychiatry

Max

“ﬁg“? vmrw

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                    <text>WWWW'WPW-w‘vi" mm.va

We

p.—

.

V

‘anl‘wkz‘uvl, m— V,v-v;

v-m"

.—-,_..

June 20, 1967

Dr.
J. Breoelmd, Editor
Marleen Jamaal of Peyohietry

-

1700

18131

W,

N. W.

Washington, D. C. 20009
Dear Dr. Bmoeland:

Emloeed

is

Canpu‘terAnalyeie

an additional copy of our report "Digital

ofthemmnﬁm inPsydxiatr-io Research "

Thispaper was presented at the recent meeting of the
Psychiatric Association in Detroit.
Thank

ya: for your consideration.
Simerely yotm ,
Pink, M.D.
Profeeeor of Psychiatry

Mme

Mszp

American

.

u‘— 'W

’1“

�</text>
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                    <text>June 20 , 1967
Mr. Robert Sluaman

Im Corporation
211 Montan Stmet
Brooklyn, Nw York

Mar

Bob,

In line with the continued developmnt of the EEG: analytic
facility of the Department of Psycmiatry at 5 East 102m“! Street,
I would like a quotation and a mitnent from 1:31 for the delivery
and installation of a special ounmmioation adapter and the
associated equipment for a Control Data 21? CRT Entry Diaplay
Unit. This unit will be
located and will comicate
with the 1800 by telaplm lines. We have mqmated delivery
of the unit from Contml Data for 11~1~B7 and would like the
I'm adapter available. at that time.

may

Please submit a formal qmtation for proper approval.

Simly yours ,
Fink, M.D.
Professor of Psychiatry

Max

MP:k'p

F. Haydn Morgan, Vice ‘Ismsidant
Research Administraticm

�</text>
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                    <text>June 20, 1967
Dr. Tuner:

M.

Itil

Missouri Institute of Psychiatry
51400 Arsenal Street
St. 10118, Missom‘i 63139
Dear Turan,

Enclosed are the additional data layouts requested by

Dr. Tabor and Mr. Preston of A. H. Robins during their
recent visit here. I would be grateful if you would aerxi
these on to them with your covering note.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>5

I

.

”viva”,

.VV._;.,.,.,.

3......

{Yr—”u...

,..,

u,

»

June 20, 1967

u

w“...-

wwmmm

&lt;-

vw-v—wn

Dr. Jmsthan 0. Cole, Chief, PR3
Barlow Building
Avenue
susu

Wimin

Room 10C01

Chevy Chem, Maryland

Dear Jonathan,

I

'

as: Isl-1256742

-

uniting to request your permission for the allocation
to $3, 700 from Mil—12567 to support special animal
pharmacology studies of cyolazocine by Dr. Richard P. Irmite of
the University of Termssee.
am

of fmds
The

up

clinical studies with cyclszocine in the treatment

of narcotic

addicts have

gone

very well.

The

initial studies

denomtmted a satisfactory dosage schedule and we are new
cyolazocine oxgmizing the comparative rs‘ndm
methadone transients in volunteer narcotic addicts.
Concmmntly, our

EEG

assth

studies demonstrated a spectrum of

activity similar to imiprsmine and a clinical stung of cyclasooine
in the
of depression undertaken in St. mum. The
results of the first eleven depressive patients are being presented at the Montreal ECDEU meetings, and mess demnstrste
clearly that Cyclezocins has antiéspressant activity. At the
same time, we have hem studies in the Mental Hygiene Clinic
at Metropolitan Ibsﬁitel and these too are showing unusual
clinical results.

mm

"

Under project WI~13358, the EEG latmtory in New York is
re-established for quantitative analysis and I am devoting
the next few mnths to an intensive analysis of the dose response
of cyclazooine and heroin in postmamotic addicts.
The animal studies of heroin and cyclszocine are very limited.
Dr. Richard P. Emits of the University of Temessse, a. sophisticated
aminel phamecologist, with a sincere interest in EEG, has indicated
that he would be willing to carry out some additional studies in
his laboratory during the next's to 12 months. He has some time
available because the proposed sabbatical in England has been
deferred for one year since Dr. Bradley is to he may in Palo Alto.

m

�:a4
law)

1...,

-

4v»

~

-.-

m“. Cole

A

A

~2-

June 20, 1967

-‘
,

My”...

.4“

...,_

"Wu—v”;

-.1—wwvmp—g-.~

After some discussion, Dr. White has submitted the attached
protocol and has indicated that these studies could be supported
by a budget of $3,700. This own is available in the present
grant by the transfer of personnel costs to our clinical funds .
Dr. Preednan has concurred in them mmndations.
Play we

have your approval for the allocation of funds up

to $3,700 from I‘m—12567 for consultationtfees to Dr. Richard P.
White of the University of Tennessee in line with the attached
protocol?

‘4

"&lt;

V-

Many

‘

-

z-r

'

;

thanks for your assistance.
Sincerely yours ,

:v“?-w-&lt;".

.

pmwmmwwxlquv-m

Pink, M.D.
Professor of Psychiatry

Max,

MF':kp

cc: Dr. White

'

zen":

W'Wwa

aammawww.

15v

".79.".

-;

n

u»

.r.

uranwm.

-».-

..
,

u
.

rmrw4lr-luﬁi

�</text>
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                    <text>.
-

,
v
A.

..,,

-

v—ww...

.A

uN‘WMWq-‘Krww-t‘vvr—‘w

raw—ran

um.

June 20 , 1967
Dr. Joseph Bird

Sterling-Winﬂmap Research Institute

Remsslssr,

New

York 1211“;

Dew Joe,

Emlosed are

some

copies of shipment notes for your

files.

Dr. Simon has requested an additional supply of cyclszocine
tablets, 0.26 11g, 50 battles x 50 tablets each. The meant
supply will be exhausted by mid-«July.

Sirmmly yours ,
Max

Pink,

PM).

messsor of Psychiatry

�</text>
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                    <text>June 20 , 1967
Mr. Larry H. Holswade

sales Engineer
Contml Data Corporation
St. Innis District Sales Office
222 South Bemiston Avenue

St. Louis, Missouri

63105

Dear Mr. Holswade:
Enclosed is a signed agreement for equipment service for
the rental of one 217 Remote Inquiry/Retrieval Display at $380
per mnth, scheduled delivery date of ll—l~67, as arranged by
Dr. Donald Shapiro and following “the quotation of June 1, 1967.
The installation charge is to be considered as rental and
will be paid as pain: of the rental charges during January 1988.
This CRT display unit will be part of the IBM 1800 installation now in the m analytic facility of the Department of
Psychiatry at 5 East 102nd Street (8th floor, Room 37) and is

supported by

USPHS

Thank you

grant

MEL-13358.

for your cooperation.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

F. Haydn Mergan, Vice President
Research Administration

�</text>
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                    <text>W

”- -—.. ,.

...

.

.w- .

~er1:

w

.—

V-rI—rpﬁ‘F'

.. w

,..._..._

"WI.~.&gt;\T:"JQ‘I. nw‘1‘h1‘zvll'

run-cup 'anwvw ”no...“ -:y w».

mwrww‘.

v'

1v. tr

a

»---»-w,

.‘i‘m'wntsz «'

»:'

”W'Yn'rrﬁ‘tva ‘ awn «mu rum

‘7‘»

vuwcv-c-vVy'r wan-w....,w-u—

.~\ --v

rwu.»

m.

.

.

A

.or.

.A

V,

wm.,.‘..&lt;_,‘..m.‘

WY“,

.1.

June 19 , 1967
Dr. Theodore A. Dull
Wallace Pharmaceuticals

Phlfacm

Cranbury,

Road

New

Jersey

Dear Dr. Dull:
Buclosed is a protocol for a proposed study of tybmate
in the moment of mrcotic addiction. I would be grateful
for your cements.
'

Would you send

the appropriate

is consistent with the
Thank you

IND?

FDA

forms

if

the study

for your interest.
Sincerely yours ,

”mﬂiﬁv‘nry

w...

r.

Fink, M.D.
Professor of Psychiatry

Max

’M"'MVCEY~‘

‘gv'l'lalirmum'

in;

.rnr

yaw-yr.

..n

—..-,,.,

‘

Mfzkp

,.

--‘

_v)rv‘

�</text>
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  <item itemId="2852" public="1" featured="0">
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                    <text>June 26, 1967
Dr. Karl Riokels
Associate Professor of Psychiatry
University of Pennsylvania
203 Piersol Building
University Hospital
Spnxce Street
Philadelphia, Pennsylvania 1910!;
31400

Dear Karl,
Enclosed

is a

for your interest.
operational in New
Operational in one

copy of mm paper from the APA. Thank you
Incidentally, the computer unit is now
York and the EEG laboratory should be

I

week.

am

I look forward to seeing

very pleased.

you

_

in Montioal.

‘

Sincerely yoms ,
245):

PM,

MiDo

Professor of Psychiatry

MF:k'p

,

.‘rmﬂ'

o
nan-1v

9:;vamwva'ﬂ‘

wk

�</text>
                  </elementText>
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an": ~W;‘wr—wv...»

v.11

Ira"

-

Wk‘umyrv-I-L" ..,.....m

m—

~_,

‘4

“I

"W“

JUne 15, 1967
Dr. Ali Keskiner

Missmwi

Institute of Psydmiatry

Arsenal Street
St. Louis, Missouri 63139
51400

Dear

Ali,

mm
is suitable for the Amateur; Jamal
is a

of the revised paper which I think
06 Pagclwwcy. I am
holdingtheorigimlandifyoumd'nmnwﬂlmkethe
corrections that ”you wish, I an
that Kathy will be able
to comet it and send it to Dr. Braceland.
I hope you had a nice time in Atlantic City.
Enclosed

m

Sincerely yours ,
Fink, $4.1).
Professor of Psychiatry

Max

Mszp

�</text>
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_

.w‘vmm‘ww‘i‘rnvr-«w r—w"aw—7'

pus: .._. ,n,’

,

June

114,

1967

Dr. Amelia B. Dmesa

Spanish Trail
Hacienda Village
1:023

Fort

Wayne,

IMiana 46805

Dear Dr. Donesa:
~I look forward

to seeing you on Friday, June 15, at
East 102nd Street. The Department will be
able to defray the reasonable expenses of this visit.
1:00

13.11:.

at

5

Sincerely yours ,
Pink, Md).
Professor of Psychiatry

Max
MFﬂcp

�</text>
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van—u

mwwmdﬂ

V

~w~--..—.rm~~n '«w—rv—wrrv-vw—n'w «Fl ﬂwmx-‘,sz mgwwu.. w».._r—..n.«.— mum. .

,.

,

June 12 , 1967
Dr. P. L. Carlton

Department of Psychology
Rutgers - The State University
New anawick, New Jetway
.

Dear- Dr. Omit-on:

I am sorry that the galley did not get directly to
Enclosed is the editor‘s galley. I wwld appreciate youryou.
waking such oomcrtiona as you find nocessary and mtumirg

it

by

air mail dmuy to:

Dr. Philip Bradley

The Medical School
Bixmhugm 15, Bugland
Thank you

for your ooOperation.
Sincerely" yours ,
ﬂax Fink, H.134

Professor of Psychiatry

Mfzkp

�</text>
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                    <text>“(-1

j.

.

:n.

mum- rv..-~‘~-\~v.--W

:-'-rw'wrrnr.‘n~vyu ;...-.—mw—;

w—w'nwfvwwm—vbr-wv-z,

June
Dre.

J.

C. Holden, Tumn
and Ali Keskiner
M.

,»-

v'

..

"now-w-w-JJ"mom-mmnuwy-um

ﬂv‘“‘--vvu‘vcr—-“—rw*'&gt;—‘v

6 , 1937

Itil

Missouri Institute. of Psychiatry
SHOO Arsenal Street
St. Louis, Missouri 63139
-

DearMike,TuranandAli:
Enclosed

is a draft

the clinical data.

copy of
As you low,

the

first

CDT

report describing

had held this back in the hope
three reports at one time and submit

I

that I could complete all
together to a journal. However, the realities of my present
position are such that I will not be able to complete the extra
analyses that are necessary before the sooner and, therefore, think
it unwise to hold this any longer.
Please read and edit this (5013371 I believe it is straightforward and is eminently suitable for the Mauvu 05 Geneaaz
them

PA

yddmy.

know

With the exception of

of

no

citation

20 which

is incomplete, I

specific questions of mission or errors which may

be troubleeane.

'

After you fave had the opportunity to edit this draft copy
I believe it should be mtyped and submitted to the Mchiuu .

Ifyouwish, Iwouldbepleasedto send itonourbehalf since'
I have had excellent relations with the Editor.
My

'

best regards.

Sincerely yours ,
Max
v

mg...

.v.’

t.

":“"Y

v,

..;..

-“,_.

‘

Fink,-

M. DV

Professor of Psychiatry.

.

WWW”?

--—-.

,

., -.~-

v-v-«www

�</text>
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                    <text>�Dr. Sugerman

~2-

June 6, 1967

If the suggestions for page six. are acceptable, then I am
pleased to have my name added to the participants in this letter.
If it is felt necessary to include the ad hmulnem statements,
then

I muld request not to

Thank

be included

in the signatoriea.

ya: for the opportunity to participate in this dialogue.
Sincerely yours ,
Max

Fink,

M.D.

Professor of Psychiatry

.

A

V

r“W‘HWW

,

�</text>
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                    <text>'June 5, 1967

HOllister
Associate Chief of Staff

'Dr‘ Leo

-

Veterans Administration Hospital

Palo Alto, California

of'
‘

DearLeo,
As you can

see fmn the enclosed carbon,

I find myself

more

in agreement with those you have criticized than with your own
position. It is sad, that even now, five years after the initial

meetings of the Camittee m: Clinical Drug. Evaluatim, we have so
few strong investigating teams for early clinioal drug work and
that the models are still, almost exclusively, based on clinical
miter'ia. .The pioneer
of Lehmann in attempting to use
psychological tests, the interest 'of Itil and myself in EEG, the
biocmmiosl investigations of Denber, are but a few of the
alternate approaches in man which my, hopefully, provide better
bases for detemination of chug patterns. But I must feel, with
Arthm‘ and the others, that yam criticism ref the few units that
are doing the hard and serious exploration, was largely unjustified,
and, as you can see fmn my letterhif they are willing to delete the
ad homénen mimosa which do wane any good, then perhaps the
-

‘

wk

dialogue will be useful.

It is

always a pleasure

to argue

with you.

Sincerely yams,
Fink,
Professor

Max

Pﬁzkp

M.D.

of Psychiatry

�</text>
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V

A...

.—

r..."

Ilrlr‘ww‘a.‘&gt;.-.ﬁ.-.vowr~

v
u:

Wrap.“

Fr}!

p~,~,x.mrwr~z

-‘

"7..

June

Acting Deputy Dimctor'
Division of Neumprannnmlogical Drugs
Office of New Drugs
_

‘

Mean of Medicine
Washington, D.C. 2020M
Dear Dr.

WW:

Iwmttotharmyoufowthaopportmﬁtytomtwithym

mug-v-

’1

1967

Dr. Joan Gimnbalvo

rut-:9.»

«guyrar

5,

and your associates and for you patience in whining the
many stages thnough which a new drug application goes before
is approved.

it

The only

fare ($33.00)
are enclosed.

involved in the visit are those of air
ewes
and parking in New York ($2.50). The air receipts
Sincerely mum ,
Pink, M.D.
Professor of Psychiatry

Max
.lﬁiw'

MF:kp

�</text>
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June

5

, 1967

Dr. Rickard P. White

Wt

Associate
,

meessor of
of

Phannaoology

Pkmnnaoology

of Tameoooe,
Manphis, Termemee 38103
The University

Dear Dick,

-"

'

“a"I-"ﬁ'f‘ﬁ‘

"1

9":

,i':ww'~')’mr~,$~

for the protocol, which is quite satisfactory.
you very
W
be meeting with the people at Sterling Wintlmp
June

I will

much

12 ,

on

will have some opportunity soon tremafter to make clear the
fimcial situation.
and

.

_

v.Kyyl‘mlgv‘xzqr',”WV-”43.13:

F
'h’

'

In the interim, Dr. Joseph G. Bird, Director, Division of
Clinical Research, Sterling; Ninth-0p Research Institute ,
Rensselaor, New York, is willing to make up to 1 gram of pure
cyclazocine (hydrochloride) available to you , if you will submit
the capies of the enclosed investigator fcmn directly to him.
My

onyqa‘fw

best regards.

our:

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Mm:
Mf'ﬂcp

_.
,4.

u

:.-

.qn-fwt—fw'swygxr‘ﬁjJ.

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3"

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                    <text>ww-

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.r

7‘“

.

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Var—A,

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“In

June 1, 1957

(SM-F‘rﬂ'VrzﬂﬁﬂUr‘Gﬁ'?‘

'

"A
7"

’7ﬁ‘5rz.

av:

TLZ'F‘Z‘SWJJMW‘V

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lWM-V-me

73-7

:g'a'suﬁzﬁn

Dr. William Guy
ECDHJ

Biometric Labcractory

Room 618

11% Nineteenth Street, NM.
Washington, D.C. 20036
Dear Dr. City:

mid appreciate receiving 200 cppies of the Brief
Paydxiatric Rating Scale - Early Clinical Drug Evaluation
Study for use in our wt~patient program. Thank you.
We

Sincerely yours ,

‘11:};

VI

:2\

;

014‘.‘5‘$§-“’

r:

Pink, M.D.
Professor of Psychiatry

a

Max

a

2:53

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13.1"?va

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32377

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�</text>
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                    <text>May

Dr.

'w

31; 1957

Tamara M. 11:11

Missouri Institute of Psychiatry
suoo Arsenal Street
St. Louis, Mssami 63139
Dear Tunan,

wart“

mweﬁ

”VH'S‘V‘VK

Enclosed

is a

copy of the preliminary data analyses which
H. Robins. AsI
Dr. Tabwwillbehemm’lhmsday, June 8, at

Isen'ttoSmithKlinemdenchaxﬂtoA.

motetoyou,

mamandlhavearmrgedtovisitﬁnithmandf‘rwchin
would be
June 11;.

wwwgmwwzflrlﬂ‘iwﬂ

Philadelphia on
and suggestions.
My

I

grateful for your

best regards.
Sincerely yours ,

no.1

Wm,

v

Pink, M.D.
Professor of Psychiauy

Max
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                    <text>1-

'I-"H

May

31, 1967

Dr. William R. Tabor
A. H. Robins Company
1&amp;0?

Cwmﬁngs Drive

Dear

Bill ,

Richnmd, Virginia 23220
w‘wvw‘

u‘
»

arm-«-

~r-.W—,-nrr-w

u
H:
v-zr:

It‘~M‘!‘.H’l-wrl'q

lnmﬂer-I-W‘rﬂr‘MM-m‘rw

Enclosed are three sets of the graphs for the preliminary
report on our barbiturate - stimilant EEG study. Please add
them to the end of the reports which you now have.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max
MF:]&lt;p

�</text>
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                    <text>"pp--

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vm.

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Mom
Congress Department

Miss T.

1967

'

Excerpta Medina Foundation

119-123 Hemngraeht
Amsterdm, The Netherlands

Dear Miss Peereboan:

.I have reeeiveda letterof inquiryfmnmyformroo—
worker, Dr. Turen
of the University of Missouri, requesting
infomtion regarding his report the “Treatment of Chronic
Psychotic Patients with Canbimd Medications" which was pane»
seated at the 1966 meeting of the CINP. In your response to

Itil

his Question, you ”indicate that this report was read as part
of Smosiun VI of the CINP'.
This is imorreot. Symposium VI was dedicated to anticholinergic medwnim in man and animala, and mother
presentation by Dr. 11:11 was invited for that swipesimn.
It was lamented in abstract in the Symposim VI abstracte;
and is includdd in the Eleevier volmne.‘ The report cited
‘

above was read aspen of free mutations. and is not
being published in the special volume dedicated to the
anticholinergic problem.

more,

If at all possible,
consideration ohould be
given to include the
of the enclosed report
“'I‘reatnent of Chrmic Psycl'wtic Patients with Contained
Medioatims“ in the Proceedings of the CINP, as published
by
Media, as it is? not germane to the volmm I
m preparing through Elsevier.

mletetm

15er

Thank you

'

.

for your consideration.
Sincerely yours ,

err-x

Fink, M.D.
Professor of Psychiatry

Mm:

awn

'
CKY‘TJ'

WW1;

.m-

Mfzkp

u
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831C:

.

�</text>
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                  <elementText elementTextId="102192">
                    <text>Dr. A.

m

May

29, 1957

Sugerman

Chief, Investigative Psychiatry Section
Man of Research in Hemlogy 8 Psychiatry

c/o

New

Jersey NemPsychiatr-ic Institute

Box 1000

'

Wton, New Jersey
Dear Art,

Ihadtheopportunitytothinkaboutyowletterin

response to mo’s editorial and would like the opportmity

tojoinyw. Ifynuwillsendmaoopyofmmplyas
soonasi’tismvised, Iwillcallyouassoonasl

haveMdmeopporthitytomadit.

Simemly yams ,
Pink, I‘M).
Professor of Psychiatry

Max

Mfﬂqb

�</text>
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                    <text>o'er:

row-:16“?!

WhW‘”

71%;}:-

I*W:‘mf'm~.§3‘i

Mey

29, 1967‘

Dr. William R. Tabor

A. H. Robins Company

We
Virginia

1&amp;0?

Richmond,

Drive

23220

Bill,

Dear

first draft of our progress
report No. 3 deewibing the EEG Wes with fenflmemine,
ambarbital, dextmmhetamine and placebo. We are enclosing
some of the tables to give you an idea of the material with which
Enclosed are three copies of the

we

marked.

I look forwazﬁ to having Mr. Pat Preston and yourself join
usinNewYorkabmtnomon‘Ihxreday, June 8.
In addition to the fenflmfemine materiel, I am pleased to
enclose copies of two depreeeion rating scales which you requested - the Honilton Scale and our own depression rating
scale modified form Lehnann~Rockliff. I have been told that
the Hamilton Scale is the one that the ECDE grasps of NIMH
will probably use. Hmever, we have fomd it convenient to
use our om scale for the time being, but will probably go
to the I-lemilton'Scele in our next study.

I look forward to your visit.
_

Sincerely yours ,
Pink, 14.9.
Professor of Psychiatry

Mex

Wk?

’I‘hegrephsdidnotxeroxmllameillhavetodothen

P.S..
.

over on Wednesday. They will be sent Wednesday afternoon,
but these reports might be useful to get started.
‘

�</text>
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                    <text>May

Mrs.
3018

New

29, 1867

Julie Toth

East 90th Street

York,

New

York 10028

Dew Mrs. Toth:
Would you please call my secretary for an appoinmnt
come
again so that we can discuss yam"

@130th

to
visit
to this staff.

Sincerely
Max

yum ,

Fink, Md).

Professw of Psychiatry

MF:kp

�</text>
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                    <text>ﬁ—vm“r"7thmv-'q

.

WW

WKW_F2V

w
.‘_~.~

"-20.91an

YW—m'rw

mwmmm

May 29*, 1987-

Mr. Donald B. Cheethwn,

Research Associate

Jr.

'

Clinical Investigation Department.
Smith Him. 8 French laboratories"
1500 Spring Garden

‘37'5'

Street

Philadelphia, Pennsylvania 19101

«

I‘z..

~—

r

Dear Don,

.

Enclosed are ten copies of a preliminary draft of our
progress report No. 3 on the comparison of the EEG effects
of ambarbitel, dextmorphetamine and placebo in volunteer

w-

,5813‘w‘4f5’43‘9"

subjects, We are including some of the data tables , to give
you an idea of the neterial with which we worked. We will
bring with us additional mterial which will serve to
amplify these data.

I look forward to joining you in Amiladelphia on
aftenmn, June 1'4. Dr. Shapiro and I will be
New
York in time to arrive at 1:00 p.111. We" look
leaving
forward to visiting with you.

Wednesday
”75:5

Sincerely yours ,
Fink, M D.
Professor of Psychiatry

Max
-

Mil-"mp

i"!

‘3ﬂﬁiﬂﬁﬁu

.;

‘

3327’

“#53334

“if

'

�</text>
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                <elementTextContainer>
                  <elementText elementTextId="105500">
                    <text>"I ..

A

,

'_

1,7,, "m“,

,.,

WW,” ,....

"wrwmlk u

,w,

1.“. "A."

.11,,mr.whwlwh -r

v

,_...., __.,v..,,.n._w

3,":

_,~,4-.

r

,7.“

w...” “4,7-.." an? ~._,._‘-p,.

«A.-

&lt;

w'-"'r"—“

My-”

....

m...“

,_
l

”w:

{mewgm

u
1"
«m.

May 21+,

1967

Dr. Alain Sanseigne
Associate Clinical Research Director
E. R. Squibb and Sons

Georges Rd.
New Bnmswick,

New

Jersey

08903

Dear Alain,

.

Enclosed are two copies of the revised protocol on the
fluphczmzine project. The only change is on page two where
Dr. Pclvan correctly edited pan: of the second
Would

nwfﬂ‘ﬂ'nuwrwrrnrvﬂ

to replace your
it be possible
Many

revised drafts?

thanks.

mph.

copies with these.

Sincerely yours ,
Max

Fink, Md).

mecssor of Paydxiatzy

MF:kp

.7...» ..,. r:~('-'r‘r.qlm'n1)“

13,—‘t-I'w.

r

~

..

war

.«1;

-

,

m)

(—

v«--

�</text>
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                  <elementText elementTextId="102195">
                    <text>a,“ WP

.W
.

._

‘

'

.,

..

,‘_VW‘W.\.‘v.-mem‘7”my ..mum:..Mum—v
V

——

-»--" I

May

'

,

vvd-n,
»

V“ 1*3'""‘vv-n'mn’w’u:JV” HI'H'T‘FWPVW-W'Wr7‘70”"

214

W"v""" """r'ﬂ

"V "

, 1957

Nemttin Polvan
Taksim - Talimhane
Dr.

Lanartin Cad. Bumn Apt. 17/].

Istanbul,

Dear

Dar.

My

1°0le:

Imgladﬁmt'fhmnlushadacmmetometwithyou

*3

about the project and nape that the first study is naming
well. I am enclosing copies of the fluphenazine protocol
as revised by yetme and Dr. Itil.

1am;

Sincerely yams ,

76’

Mr

n
m“-

fiv.&amp;‘2'¥§;)‘?ﬂ5¢"llr‘

Max

Pink,

PM).

meesaor of Psychiatry

.»L~zu«r

HPﬁq)

"""'"" m-vr,

�</text>
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              <elementText elementTextId="28701">
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              <elementText elementTextId="28702">
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              <elementText elementTextId="28703">
                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                    <text>may 23, 1967

Dr. Jonathan 0. Cole; Chief,
;

Barlow Building

susu Wisconsin

Room lOCOl

Tynan—w-

Akue
,

Chevy Chase, Maryland

"lwﬂ‘l

PRB

'

__

Deer Jonathan ,

1er

I

am

taking the liberty of writing regarding a proposed

the subject of ”EEG and Hanan Psycmpharmoology"
or "EEG and mm: Behavior" for the forthcoming CINP meetings
in Spain in 1958'. A symposium on this subject was held on the
occasion of the World Congress of Psychiatry in 1961. This
reviewed the methods and experiences then available and indicated
that there were interesting relationships between EEG and drug
symposimn on

effects but that the methods were relatively poor.
Since then, two major symposia rave been held

.

and published
(Glaser - Yale UniVersity, 1963; Wilson Duke University, 1965).
Also, there have been two major discussions of the problem of
dissociation of EEG and behavior with antioholinergic drugs, at
the, Society of Biological Psychiatry (1965) andthe CINP (1966).
—-.

‘

Recent studies of more refimd objective methods of
quantification has enhanced these studies mmssurably. The
enthusiastic interest in the relation of the EEG phases of
sleep to behavior and to drug effects have also stimulated

my new

studies.

The spectrum

is broad,

.

of relationships of

enoanpessing the

EEG, drugs and

behavior

specificity of'drug effects, the
relation to diagnosis and the relation to treatment response.
I would like to ask the Program Committee of the 1968 CINP’ to
consider

an all~day symposiwn on the subject "EEG and Human
Psychoplnrmacology. " I would be pleased to- organize and chair
such a smposimn.
'

'

Sinceme yours ,
wi'f‘

.:

'r'

wwm-W‘Z.‘

"new

wavin-

-,

Mex

Fink} M.D.

Professor of .Psychaitzy
MF:kp

�</text>
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                    <text>May 23 ,

Dr. Jonathan 0. Cole, Chief,
Barlow Building,
5050 Wisconsin Avenue
Roan 10601
Chevy muse, Marylam

Dear Dr. Cole:

1987

PR8

RE: MEI-13358

It is with considerable satisfaction that I report our meant
progress in the study program "Quantitative Em Sonics in Psycho—
phcrmaoology," Lawn—113353,. and mquest your comidcmtim of
a revision of the total budget period, not only for 1967 but for
the full grunt period - Jammy l, 1967 tlmmgh Dooonbcr 31, 1970.
Dining

this initial year of transfer of the study program
New York, I love boon fortunate in being able

firm Misacmri to

to make the initial staff appoinhmmsa under the mlmntaxy
grant 14143003 and owing the minder of 1967 will need mob
loss in pummel funds. As you
transfers frcm personnel
into the equipment, alteration and renovation categories have
been appmvcd; Attached is a revised budget allocation plan for
the minder of tin study period mick follows closely the
original application, but which takes into aocmmt mo realistic
estimates of our needs in this now Institution.

m,

'mcm am no changes in

xuu-v

*2:th

may of the restricted omega-mics of
and mmvatim except that the
alteration
travel
oquiprmt,
or
allowance of $0,000 in 1969
a.
estimate
wacvctim
of
original
has been inmascd to $8,000 and an additional allowance of $4,000
is mqucsted in 1970. It is our expectation that we will be
movingtothencwcamnmityﬁmtalﬂcalthccntermwmnear
the end of 1969 and I on certain that mmvationa will be mceoomy
to provide my satisfactory air Mndling and electrical oomcctions
for this study program.
Mother major change is in the allowances for omputor rental.
The origiml Midgets mm prodioatod on our processing the rating
scale data using optical page readers. The Director of the Gonputer
facilities of the New York Medical Collage and an active participmt
in this program, Dr. Donald Miro, has recently indicated that we
‘

‘

A

wouldbebettcrscmdtouscdigitaloscilloocopctominclaand
$1me links to the 134-1800. For this mason, we are rebudgeting

—
A

“v,

""1531?“

mute-r mtal costs.

�1“,”.sz

no

.

~2~

Dr. Cole

May

23, 1967

vmrwnhv

W.“

7-“

4..v,.,.,..-.,~

‘

year period is identical
March 8, 1967.
dated
with that married in the notice of grant
The

total

amount mannered

for the

4

Thereallomtimoffmdamquestadmbwnapprwedby

-v.

ﬂmEmmtiveDimctoroftMDeWtofPsychiatwmdthe
I”.
Morgan.

Vice Preaidezrt of Research

Mminiamtim,

Haydn

"Aw-4.1.,

”‘WW‘“

Many

thanks.
Sincerely yams,

ermvmryom:

.5-

&lt;

Fink, Md).
Professor of Psychiatry

Max

,,

t
‘

a

1'1?sz

.g

.nr‘,

wh'wrwvuz.w-r-M=u~mwznu.

‘

Approved :

"P.

Haydn Morgan, Vice

Research

A,

Wﬁu‘rwra’x‘y‘

Pl"!

W'W-WWW"‘WJW.TQ1WWWMV-)

’
«

Pmaidem

Mninistmtim.

�</text>
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                <text>Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).</text>
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                    <text>:nrvlwﬂrriww‘"u:u'~-"!F~C:au\x‘\l AWW'W‘IWr'V

w

n

-

‘

,

V:"~‘v

-.--

m:

'I'AV'VII‘J"

¢

~

.

-

w.-rmvr-awrm~».=-o

‘Ww'r‘nww

.-

.ww-x-ur-w-nw-v-vwnun

--:—wmu\r-n

a“

~.—,

*v‘y

w—v

«vvv '1‘ .. :mvw ~— +'v-rw~

"www—

.
vw

.-

-—-m

«v

rmrﬂqwm‘rw—znw

May

22, 1957

"~an

Dr.

~

-.4-fvlw

R. D. Roecker, Chairmen

Psydxiatric Sectim-

Overlook
.HVWWv—v-erﬂmxv-Jwr

w.

Swank,

m.

1

New

Jersey

'

07901

Dear Dr. Foacker:

EWWisastmeeduminthein’

”—wn

..f.

Ibepital

‘

patient service of this hospital. At the present time

is mustered by an metresiologist.
This is a munity hoepital and them are no specific
(merges for these
anesthesia

servieee

and

Psychiawists minimally adamieter their own anesthesia
the only qualification required is that he be board certified

Vinpeydxiatxy,alicensefxunﬂne$tateofNewYorkandthe
willingness to mldertdce the treatment.
V

‘r

Sincerely yows ,
Fink, M.D..
Professor of Psychiatry

Mex
.

Mf'dcp
"mum-"”4,

w—v

w.»

r
&lt;

i'vw'}s."‘.:nn“:

‘

«-

”ﬁrm“

'WW-m'w'

~vme—mmmmm—v,

w'

r ""—

�</text>
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                    <text>.A

w.”

mrvwi—v—uwr-mnmmw»—-.-.

May 22 ,

1967

Mr. Richard Weider

Tine/Data Corporation
#90 San Antonio Road

Palo Alto, California 93303
Dear- Dick,

At the recent meetings in Detroit I had the opporumity to
meet with Dr. Overton who is now working in the laboratories
of Charles Shagass at Temple University in Plﬁladelphia. He
is intematedhiin the same problems that interest me and you
my wish to send him a description of yomr Time/Data 100. Feel
free to tell him that I suggested that you do so.

Sincerely yburs,
Fink, M.D.
Professor of Paychiaﬂy

Max

Mf‘ﬂcp

�</text>
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                    <text>.-

www-

g~;v—(7“.1‘&gt;;v

mum-um:(7.».‘var'n -"",w'1_'

—.

‘t::-r

3?”;ersup. 4...,

“7-

m: WWW—WA .mxz‘.vg\vmav- mun-.- p.~.usu~~.~,—.w_~..

May
....,

.

H

.mr

.v;

—n

1,”..memmwygpwmmmwvum,

w

7"

"my-Kr

,1,“

”3.4.,“ ”A“;

”1., r~~_.-p4";'nw~ ,'~&gt;.‘q4"":wnwcnv:.~.- WW,

22, 1957

Scare

me

Moan

Acadany of Psydnmmlyais
125 East 65th Street
New York, New York 10021

MW:

Enclosed

in yam

is a

check

bill of April 10,

in the mount of $10.00 as requested
1967.

My

records indicate,

Imam,

that I paid my associate umber-ship dues earlier- this year,
intheamuntof$5.00.
for
scientific associates has MItoasthtthedues
Men increased to $15.00?
Sirmmly yours,
Fink, M.D.
Professor of Psychiatry

Max
,(
.

‘p-«Wr:'Ir-—A.~vw1-!11n:&lt;

14.9w“

vv

.-,

-':\'&lt;"

ww.wn.ypw\va.wy,w-—

~wmvvﬂn.~a{’vwz$

Mszp

.

7

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,7.

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.3 1

�</text>
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                    <text>May 22 , 1967

meeasor P.

B.

Wiley

The Madical Seine].

'

Biminghan 15, Exgland

Dear Philip,
-

'5'

l""!""}~€

‘;.;;g-;gg;.mzv,n'r:r.

I will be attmding the matings of the Mariam Em Society
inAtlantio Citywﬁlmldbeplaasedtospend-asmay‘mmas
are meessary to complete the editorial work on the book. If,
however, you would prefer to come to the United States a day
earlier or stay' a day later in New York, perhaps we could mrk
better in my offices. In either case, I will be pleased to

if

a secretary available and
you bring with you the revised
galleys, page proofs, up any otter matm'ial which may be helpful,
this mud be the best opporttmity for 118 to get together.
make

I
My

look

fmazd to Meaning ym in the

best mgwds.

Uni-tad

States.

_

Sincmely yours ,
Max

PM,

14.13.

Professor of Psychiatry.

Mf'ﬂcp

as.

Enclosed

is a (:1ch for my rmbemhip cause in the

C.I.N.P.

�</text>
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                    <text>May 18 ,
«.47

u

I
«awe

vw‘vK—Aqmnrmw-wr

1967

Mr. Ph. Vuysje

Head, Congress Department
Excerpts Medica Foundation
119-123 Herengracht
Amsterdam, The Netherlands

Dear Mr. Vuysje:
”aqn-“ru-ﬂw‘w

.

I would be pleased to subscribe to the reprints of the
symposium. It would be perhaps more
distinctive if covers could be provided and I would like to
know if this is possible and what it would cost.
abstracts of this

In the interim, please
of the abstracts.

book our order

for

200

copies

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max
MF2kp

WWW-1'

v—rtvw-

.

�</text>
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                    <text>:w-w

vrv-r’V'WK"

May

18, 1967

In". Reina E. 1311mm

Clinical Dimctor
Dwglas Hmpital

6875 LaSalle Blvd.
Verdun, Quebec

Canada

DaarDr. balsam:

for yaw invitation to join the Q.P.R.A. mating
I will try to arrive mud 12:30.
Incidentally, m MW: recently purliahad our
withthiothixmandmﬁdhepleasedtodiscumthepapem
being pmnented fun the vimpoint 01' that axperim. Thank
you for the invitation.
Thank you

on June 21.

mime

My

best mgmds.
Shmamly
Max

Fink,

yam ,
14.1).

Professom of Psyctdatry

�</text>
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                    <text>mwvf‘VV-"w'ln

_, "~Ov-V

urn-“v.

.

r

.

.

:-

WV,“

,

_

May

L

L

{

9

.

,vv ’

,,

" _' " "

,

,

._,.__,ﬁ,,.,.,..,..,,,m

ma: :wrsrw,‘=m

18, 1987

Wt

Mr. Ph. Vuysje
Head,
Exoarpta Medics. Poundatim

Was

119423 mmwgmcht
Ametardm, The NetMrlands
Dear Mr. Vuysje:

j,

L

L

I muld be phased to subscribe to the reprints of the
abstracts of this 83415303114211. It muld be perhaps more
diatinctive if covers could be pmvided and I

would

Wifthisiapossibleandwmtitwouldoost.
In the inmr-im, please
of the abstracts.

book our oxder

for

like to

200 copies

Sincerely yams,

;

E

g.

Fink, 101.13.
Profesaor of Psychiatry

Max

‘;

MFﬂcp

"gnaw-nun“N— avuse'wwn—uwxu—p.

..

»

:s

�</text>
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                    <text>May

'
»

17, 1967

Officer

365th General Hospital

100 N. Forest Road
Buffalo, New York 1&amp;221

Dear Sir:

IamwritinginsupportofthemquestofDr.ArthurZaks

forassigunentintheNewYorkareadtminghissunmertmining

PW.

Dr.

Zakshasbeenanactiveparticipmtinthestudyof

cyclazocine which is a new agent in the treatment of narcotic
addicts. This study is a special research project of the
Department funded by the National Institute of Mental Health
and the New York State Narcotic Addiction Authority. He has
been centrally involved in evaluating the untoward effects Of
this canpomd. The studies are prOgressing actively and will
continue for the remainder of this year.

helpful if Dr. Zaks could continue his
observation of these patients. He has already deferred some
of his vacation time in order to continue the study program.

It

We

would be most

grateful if it were possible for him to
military time in the New York City area.

would be most

spend his

Sincerely yours ,

Fm,
m
Professor of Psychiatry
MOD.

Mszp
cc: Dr. Zaks

‘

�</text>
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                    <text>May 15 ,

1967

Dr. Richard Abrams
10a Childmss

Shepherd APB. Texas

DearDr. Abrams:

sorry for the delay in answering your letter of
but
preparations for the APA occupied most of my
April
time. I have read your paper with interest and have taken
the liberty of marking it with the questions that occurred
to me as I read the text. I think it is sufficiently clear,
however, it should be submitted for publication.

I

am

1'4,

You are correct that the changes induced in unilateral
and bilateral ECI‘ were significant in their changes in the
Hamilton Rating Scale. The data for the Bedmberga Scale
were too scant to be useful.

I have had the opportunity to visit Dr. Blachly and
that his technique , which pennits three to six treatto be given in one morning, is probably a useful method
to be tried. He suggests that the differences between his
observations and those of others is related to the degree of
oxygenation. IhavealreadyspokentoDr. Kalinowskyand
perhaps we will be able to mdertake such a study, following
his line of investigation, if we can obtain the services of

found
ments

an experienced

anesthetist.

Such

‘

a study is of special

interest may since the its-patient services are undertaking
a special study of the rapid treatment of all admissions to
the service. They are particularly interested in any device
that may shorten the treatment period and such a mthod as

fits well

Dr. Blachly suggests

It would

be quite helpful

earlypartofJuly,

as

can plan the study more
My

with our present needs.

if you

could

Ithirﬂchillbe
definitively.

visit during the

inNewYorkmdm

best regards.
Sincerely yours ,

.,
3..

WIT/;:

Fink, M.D.
Professor of Psychiatry

his-.111W‘Wl

Max
.7-

r,
p"

W;—.qu..\h

rw‘rW-Wn

MF:)q&gt;

�</text>
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                    <text>May 15 ,

‘7.""Yp'f‘

"1w.-

w

venr—m

-

'
M

Ir.

Joseph

555

Prospect Place

1967

A. Beulah

TheJewishHospitalomeoklyn
Brooklyn,

New

,

,
97M
£97

York 11238

war-v;

Dear Joe,

.
‘4

'.
'

aft"-

155‘an

W“

”(UM-.947!“

A,

I have read the appendix to your research grant with a great
deal of interest and find that the associates at Columbia University
are most sophisticated in the analysis of EEG sigmls. Their
euphasis on power spectral density is logical. but it is probably
the more expensive way of handling the problem which you face.
It seems to me that the initial approximations for your work are
no different than our initial appmximatdnns and for these, period
analysis is faster and much less expensive. We lave already
developed a variety of methods of Using the period analytic
output to characterize the patterns in the EEG and these might
be useful in detennining the changes which you anticipate in
your animals.

.

1;

”'3!

"musing-5V“!

.

5w

(shag-z.»

4;»1—yﬂ'n‘t‘;

My second tMught has to do with the idea of a library of
tapes. This is indeed a good idea, altmugh I wonder if saving
the digital tape is the best way to save the data. It does
man, that any analyses you wish to undertake must he done in
laboratories which cam mad that tape. My om predilection is
to save the analog information. However, this may be too

expensive.

Incidentally, I found the enclosed article in the Medical
section of the J.A.M.A. recently and am sending it to you.
The differences in the two records described in this note are
probably masurable by period analysis.
News

laboratory shmld be in operation by September and we
to have you and your associates visit us with
the assurance that we will ooopmte in any way that we can.
My

would be pleased

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

�</text>
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                    <text>«v»

May 15 ,

The

1967

Editor

Dictionary of International Biography

Narnia

House

Francis Street

s.w.1, England
Dear Sir:
London

Enclosed

is a

and include

it

copy

of

in your moent letter. I
11:
in

my

curriculum vitae as requested

would be honorecl to have you abstract
the Die/dancing 05 Inzmazéonaﬁ Biogmhg.

Sincerely yours ,
Fir’k ,
m
Professor of Psychiatry
M O D0

MFﬂcp

�</text>
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              <elementText elementTextId="28832">
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                  <elementText elementTextId="102204">
                    <text>May

15, 1957

Box YGBRS
New
New

York Times
York, New York

Dear Sir:
The Department of Psychiatry of the New York Medical Cdlege
embaﬂcing on a series of extensive evaluatioh study programs
of the treatment methods in a oormmnity mental health center.
It is possible that your experience my be useful in such a
and I am writing to invite you to submit a curriculum
pviogram,

is

tag.

If

you care

afternoon at

to call, I

212 369—4900.

Trunk you

am

generally available in the

for your interest.‘
Sincerely yours ,
Max

MF:)&lt;:p

Fink,

M.D.

fessor of Psychiatry

�</text>
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May
;
E
_

i

Dr. Ernst Rodin
Department of Neurology

Lafayette Clinic
951 East Lafayette

Detroit, Michigan
Dear-

L#8207

met,
I

wamt

to take this opportunity to thank you for the very

interesting
pleased to get to

evening

here Doctorate.
Again,

my

I spent in your

know Martha

home

last

week.

I

was most

well and congratulate you both on

thanks.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

�</text>
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1967

Box n31

Science

1515 Massachusetts, N.W.
Washington, 13.0. 20005

Dear Doctor:
The Department of Psychiatry of the New York Medical
College is smarking on a series of new programs, mung
which is one dedicated to the evaluation of changes in
brain function associated with psychophamaoologic agents.
We are establishing
a research laboratory in HQ and computer

techniques of analysis. The drugs mder investigation will
be the majority of psycl'nactive agents , and the populations
will be“ the acute mentally ill and narcotic
addicts.

If such a study program interests you, I would be
pleased to receive a copy of your curriculum vitae.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MPtkp

�</text>
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                    <text>May

BOX

15, 1967

#53

Science

~

1515 Massachusetts, N.W.

Washington, D.C. 20005
Dear Doctor:

The Deparment of Psychiatry of the New York Medical
College is embarking on a series of new programs , wrong
which is one dedicated to the evaluation of Changes in

brain function associated with psychophamacologic agents.
are establishing a research laboratory in EEG and computer
techniques of analysis. The drugs under investigation will
be the majority of psyclnactive agents, and the populations
will be the acute mentally ill and narcotic addicts.
We

If such a study progran interests you, I would be
pleased to receive a copy of your miwlmn vitae.
‘

Sincerely yours ,
Fink, M.D.‘
Professor of Psychiatry

Max
.

,

"furry—”mu

.

-W—w

MP:kp

�</text>
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                    <text>May 15 ,

1967

Dr. K. Muller
Department of Bleatzophyeiology

Wial

Allan
Institute
1025 Pine Avenue West
Montreal 2, Qlebec
Canada

Dear Dr. Muller:
Thank you

for your letter requesting information about

the canputer analysis of evoked maponees. ﬁring the past
few years, we have carriedrmt few studies with the evoked
response, and in general have followed the descriptive method
thatmoetworkemueeinevaluetimthewtputofﬁxeCAT
oarputer.

Porthismason, Idomttlﬁamtl‘atotmmﬂndeare

of any special value to you. I may suggest, hcmever, that
5mm information regarding the analysis of evoked
responses can best be obtained fm Dr. Charles Shagaes
at Temple University in Philadelphia.
Thank you

for your interest.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
MFﬂcp

�</text>
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                    <text>.,W,

“y“-..

,v

May

v—,,

.

15, 1967

n
V,_

_

«WWW-«rrn'ww‘

.u,

Dr.

Issai lcfhowitz

Claxksville Road
Princeton Junction,

New

Jersey

V.

”WI-‘.VK~.W;..&lt;

Dear Dr. Lefkmitz:
Within a week of the time that we discussed your interest
in magnetism, the enclosed article appeared in the New York Times
(May 6). Apparently Dr. Cohen has built the room you suggested.

Iantakmgthelibertyofsendingyouoopies ofthetwoarticles

and wonder

if you could

answer a question

for me.

The electrical activity of the brain as recorded on the
surface of the scalp is generally calibrated as varying between
50 «and 150 microvolts in amplitude for leads which am approximately
one centimeter across on their surface and separated over the
scalp from two to five inches. Can Dr. Cohen's laboratory measure
the changes in electrical activity from the brain.

Perhaps we

will

have an opportunity

to continue our discussion.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

Mszp
“,1...“

«u

«rs-u:

w—v

A

vqua-m,

.

.

�</text>
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                    <text>wand-"v '31:"!

\.

r

v:- .A

,

y

wmvrv --:-n-' Mm'v

wavy-v

~

-~

'7"‘&lt;-'y'wl&lt;v~‘-I‘wrv y—v'

w

(«V»HI‘:"-¢-:-Imw‘,‘1

may

V7

'

.

7—

.

May

"w-‘Iwrr '{IY4'—\:m-J‘EIHV'.L-v 'w’ﬂ‘JI'JPK'p-nvvaH -\--1V‘

m-xw—

2

F3 inn-ﬂ"

10, 1967

E

E

—

A

v.

Wq.vvmn—.-v.v

aw

w

v

w

m

mam-um.»

Dr. Mamie;

Editor

Micah

..

‘7'

.-

p...”

-v.

57.1

Journal of Psychiatry

Dear Dr. Braceland:
Enclosed is a copy of the report "Digital Oanputer Analysis
of the Hum BEE in Psychiatric Research" which was mad at the
APA in Detrvit.

Ifthisdraftisaccetedforpublication,wewillbe

pig-236d
1)

ts.

to suhnit a copy

th citations

and

original glossy

Simerely yours,
Fink, M.D.
Professor of Psychiatry

Max

“rm“

._

J. Braeelmd

MP:kp

“nu

.

4.

.

W

van,

-v

--

~~

w

.r

I

my

�—

‘

sz-ﬁvm

,

May

Mr. Harold Mehling,

Psychiatric Progress
3 West 57th Street

New

Deaer.

2

Mehling:

Enclosed is a preprint of our report to the annual
meeting of the Mariam Psychiatric Association, "Digital
Computer Analysis of EEG for Psychophamecology." It

wwldindeedbehelpfulifyoumuldcheckwithus before
of this material, for I believe we can provide

making use

you with additional figures, including glossy prints
which would make the presentation more satisfactory.
Therm you

for your interest.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Mm:
ryn—uw

m

Editor

York, New York 10019

ri'lﬂﬁwﬁmwr‘fm'15w)K,.131l'a",:rhmmf,lw.

.,

2, 1967

Mf‘ﬂcp

we.

:w‘ ”v.4” .vw.‘

�</text>
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                    <text>May 10 ,

1967

Dr. Amelia B. Donesa
#023 Spanish Trail
Hacienda Village

Fort wayne, Indiana #6805

Dear Dr. Donesa:
Thankjwmxfn~your letter'of’May 3.

I

would

like an

opportunity to have you visit with us, if that is possible,
to discuss the opportunities within the Department of
Psychiatry.
Ext.

would you
2H5.

Many

please call
thanks.

my

secretary collect at

212 369—7900

Sincerely yours,
Pink, M.D.
Professor of Psychiatry

max

Mfzkp

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                    <text>May 8 ,

1967

Dr. Willian P. Bemjmin, Secretary
Nassau Hampsychiatric Society, Inc.

1200 Stwart Avenue
Garden City, New York 11533

Bill,

Dear

New York, I have asked
m inBranch
of the American
District
Psychiatric Association in order to participate in their

As my

principal office is

to join the

New

York County

program.

While I was a member of both societies before having
for Missouri, I find now that the rules of the APAche this
double membership impossible and I am, themfom, requesting
a transfer fmn the Nassau (Now York) District Branch to the
NwYorkCountyDistrictBranchofthoAPA. Iwouldbe

gratefulifymmdaignﬂumlowdfmandsemmn
Sonnet, Roan 460, New York,
to Dr. Sidmy Malitz at 11 West

New

York 10026, Secretary

of the

‘42

New

York

District Branch.

I do not low if it is possible to officially cmtimc
in the Nassau Nmpsychiatric Society, but I would like very
rmch to cmtinue my association unofficially 3131 look fomm
to oontinuim to attcm the public meetings of the society.
My

best wishes.
Sincerely yours ,
Fink, 11.1).
Professor of Psychiatry

Max

MP:kp

cc: Dr. Jay Stanton

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                    <text>1967

May 8 ,

Dr. Jay Stanton, President
Nassau Nauopsychiatric Society, Inc.
27 Maple Drive

Great Neck,

New

York

‘

.

Dear Jay,

Bill

told you, I had attempted to join both
District Worms but find mw that
is impossible. It is with a feeling of regret that
it
I must
ask for transfer from the Nassau Nempsyclﬁetric Society
to
the New York District Branch and assure that I trust also resigx
from
the

As

New

the

may have

York and Nassau

Board

of Directors.

It

has been an Inner and a pleasure to work with you
few nonths and hope that I will have many
to continue our association at the public meetings ofopportunities
the Society.

these past

Please accept

my

thanks for your confidence. in me.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

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                    <text>May

8, 1967

Mr. Want A. Muth
808 West End Avenue
New

York,

New

York 10025

Dear Mr. Muth:

Thankymverymchforcaningtovisitus. Idonot
we rave an opportunity for your talents at this
time, buthopethatwexraybeabletooallonyouassoon
think that

asourprogrammquims it.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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Dr. Anthony R.

1967

May

Adnjnistmtive Health

Alexander Planing House
Elephant and Castle
Landon SE 1 , England
Dear Dr. May:
Enclosed

decanoate as

I

is a copy of our report
promised.

I trust

it

on fluphenazine

is helpful.

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

�</text>
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Dr. Vincent A. Joy

Director, Clinical Research
Squibb International
lH50

New

Park Avenue
York, New York 10022

Dear Dr. Joy:

I

Enclosed are two copies of our fluphenazine report.
if you mld send one to Dr. Daniels,

would be pleased

as reflected in your

letter of March

3, 1967.

I trust this is helpful.
Sincerely yours ,
Pink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>May 3 ,

Dr. Joseph Bird
Sterling—WinthrOp Research
Rensselaer, New York 1213a
Dear

Joe,

that

we

It was nice having

you

1967

Institute

visit. I regret that the date

picked,
to be unsatisfactory for
would
be grateful if you would
our visit to Rensselaer. I
and
me
time.
we
another
call
can set
WIN

May

Would you

20,7“0, .25

22, turns out

bottles of
tablets per bottle) for the

kindly arrange to send
mg (50

me #0

continuation of our antidepressant study.
Many

thanks.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>May

2, 1967

Stefan Bogen
Senior Research Associate

Mr.

Department of Medical Investigation

Hoffmann-La Roche Inc.
Nutley, New Jersey 07110

Dear Mr. Bogen:
Thank you very much for the supply of Librium capsules
and placebos which have arrived and which will be most useful

in our teaching progem. Unfortunately, the supply sent was
5 and 10 mg capsules.
Since the majority of our patients have
dosages above 25 mg, we have found the 25 mg capsules most
exchange the 51:13
usefulandwemuldbegzeteful ifWecould
capsules for an equal number of 25 mg capsules.
We will maintain an inventory of the medication to present
to you and the rm. Records of disposition of these medications
will be maintained in the Mental Hygiene Clinic.
we will be using Libriwn as a comparison drug
some of our study programs assessing the relative
anti—anxiety agents , I believe you would be

Insofar as

initially in

efficacy of
interested in our forthcoming observations and will continue
to cammicate with you.
Thank you very much

for your cooperation.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MI':kp

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                    <text>May

Mr. Harold Mehling,

Psychiatric Progress

2, 1957

Editor

Street

3 West 57th
New York, New

Deaer.

York 10019

Mehling:

Enclosed is a preprint of our report to the annual
meeting of the American Psychiatric Association, "Digital
Computer Analysis of EEG for Psyclnphamaoology. "
It
would indeed be helpful if you would check with
before
us
making use of this material, for I believe we can
provide
you with additional figures , including glossy prints
which would make the presentation more
'

,
-

satisfactory.

Thank you

for your interest.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

Mchp

�</text>
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                  <elementText elementTextId="105511">
                    <text>May

2, 1967

Dr. Jonathan 0. Cole, Cl'xief, PRB
Barlow Building
susu Wisconsin Avenue

Room lOCOl

Chevy Chase, Maryland

Dear Dr. Cole:
Under the grant MEI-12567 "Pharmacotherapy of Narcotic
Addiction" and with funds for equipment which are already
available, we would like permission to purchase a Priden
desk calculator with square root and automatic decimal
control, to assist us in processing the cyclazocine and
other psychophazmcological data. May we have permission

to allocate $1,695 of approved equipment funds for this

purpose-

-

Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>May

2, 1957

J. Casteren van Cattenburoh
Advertising Manager
Elsevier Publishing Canpany
P. 0. Box 211
Jan van Galenstraat 335
Amsterdam, The Netherlands
Miss w.

Dear Miss Cettenbm'ch:

nunkyouverymchforywrletterofhpril

2H.

Iam

indeed grateful that Elsevier will change all pmtional
material in the future and suggest only that there be one

to the listing which you give in your letter. It
academic degree, M.D. , be included
and wwld suggest that the proper designation be: Max Fink, M.D.,
Professor of Psychiatry, Department of Psychiatry at the Miami
Institute of Psychiatry, University of Missouri School of Medicine,
amendment

is appropriate that the

St. Louis, Missouri.

for your oooPemtion. I regret very
earlier letter did not reach you in time to change
the advertisement, but hope that this clears the issue for the

much

Thank you very much

that

my

future.

Sincerely yours ',
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

�</text>
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                    <text>May

Box

2, 1957

ml

Science

1515 Massachusetts, MI.
Washington, D.C. 20005

Dear Sir:

advertisenent in a recent issue of Science regarding
a wish for an appointment as biostetistician is of interest to
us. The Deparment of Psychiatry of the New York Medical College
has recently anbarked on an intensive study program of the effects
of changes in EEG signals in relation to changes in behavior
induced by psychoactive drugs in mental patients and narcotic
addicts. The laboratory is equipped with an IR! 1800 system
and we are anxious to expert! the statistical approaches necessary
in the analysis of these signals.
Your

The appointment

is in the

Department of Psychiatry and would
psychophamaoology studies , evaluations

enconpsss omsultetion in
of mannent, and other related applications.

If this

interests
a copy of your curriculmn vitae.
appointment

you ,

I

would

appreciate receiving

Sincerely yours ,
Mex

Firm, M.D.

Professor of Psychiatry

�</text>
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                    <text>May

1, 1967

Dr. E. F. Domino
of Pharmacology
University of Michigan
M6322 Medical Science Building
Ann Arbor, Michigan

t

DearBd,
Your question regarding

the proof of the abstract of

your paper "Role of Cholinergic Mechanisms in States of
Wakefulness and Sleep" can be easily clarified. The complete

article is to appear as part of the volume on Antidwlinergic
Hallucinogens in Magma Ln Elwin Rumch, and you have
already received galleys of that article. The abstract will
appear as part of the Proceedings of the Vth International
Congress of the GIMP, and you have received a galley from
Excvtpta Medina.
The volume

quite soon.
My

is

now

completely in galley and should appear

best regards.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MF:kp

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                    <text>May

1,

1967

Professor Philip Bradley
The Medical School
Birmingham 15 , England

Dear Philip,
Enclosed are six note galley proofs from the
cholinergic symposium. In addition, Dr. Itil sent
,

his

copy of the proof for this volume (No. 2813) and
have read and concur with his cements. Incidentally,

author's

I

anti-

me

is asking for 300 reprints without covers. If at all
possible , I would like an additional 100 for my personal
he

use and

it.

if

these can be supplied with covers , I

would

prefer

to the other proofs , there was little
difficulty with those of Carlton, longs, or Bures. With
regard to the article by Ilyutchenok, I find it very poor.
The text is poorly edited and the linotypist broke too
many words incorrectly. It is difficult to read. and the
style is too foreign for our usual audience .. I have marked
some corrections and suggest that you mark others. In
addition, the citations are incomplete and this requires
With regard

_

someone with experience with

the Russian literature.

Dr. Ilyutchemk uses the names Of drugs which are
in our literature. Perhaps , for his article or
for the book as a whole a dictionary of drugs with their
equivalent names should be provided.

uncommon

'

to the paper by Domino, I found the
present order of text and figures difficult to read. I
would suggest that the results, pages 16, 17 , and 18, should
become pages 5, 6 and 7 , following imediately after the
methods section. Page 18 slould end before the conclusions
and amnesty and the figures might appropriately be inserted
as pages 8 to 18. The section of conclusions and suzmxary
With regard

should then be included as pages 19, etc. Mﬁle this will
split the conclusions and summary froth—the main body of the
text, will place the figures in closer approximation to

it

the relevant text.

�Professor Bradley

-2—

May

1, 1967

There appears

to be a similar problem.with the report
set up, the tables appear on pages 2
hot are related to the text of pages 7~ 8. I have indicated

by Vojtechovsky as now

to 6
in the proof the possible location of Table I (page 7), Tables
II and III (page 7) and Table IV (page 8). This is equally
important for the figures which should be r€1ated to the text

wherever possible.

perhaps should be reset at half—page
it is confusing at present, or, the two
halves of the figure should be marked by captions of "Figure
and "Figure 9."
Figures

8

for the text as

and

9

There

is the use of a strange

Table

V

its

floccilegium. I
in my dictionaries.

do not know

all possible,

position.

8"

term on pages 9 and 1a does not appear
meaning and

it

should be related to the text of page 1n if at
I have indiCated its approximate relevant

and

I look forward.to the next galleys and to your comments.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max
.

MF:kp

�</text>
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                    <text>May

Miss T. Peereboan

Games

1, 1967

-

Department
Ebcoerpta Medical Foundation
119-123 Herengmcht
Amsterdam The Netherlands

‘

Dear Miss Peer-shoots:

molosed are the galley proofs for the Symposium VI
"Anticholinergio Drugs and Brain Function in Animals and

Man"whioharetobepublishedaspartoftheroeedings
of the Vth International Congress of the GIMP. I have reviewedthesequencyofpapersandmuldmmndthat
.

they be published in the order in which they are sent to
you, notably, the inuoduotory statement; followed by the
papers by Bradley, Longs, Domino, Itil, Pink and Itil,
Carlton, Bursa, Hers, White and Rudolph, Cumlio, Boat
and
“iiimioh, Votava at wt. , Votjeohovsky' et a8. and Vitek

st

.

I

have reread the introductory few

lines and

am

taking the liberty of enclosing a better smmary of the
full symposium. If it is possible
to publish these few
paragraphs, I believe they will enhance the symposium
ixmeasmebly.
Separately, I lave returned the absuact for my
presentation in this symposium with a request for reprints.
Perhaps, if the full abstracts of this symposium are
published together, it may be possible for the printer
to

moffamallnmnberofalltheabstrectsinaoover.
This would be
a valuable

manento for the participants
to pay for such a reprint.
Thank you for we opportmity of seeing these
Incidentally, I have written to Dr. Domino answering proofs.
his
question directly.

and

I

would be pleased

Sincerely yours ,
Pink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>May

Mr. James L.

1 , 1967

Sangston, Editw

The Williams 8 Wilkins Company
l$28 E. Preston Street
Baltinme. Maryland 21202

‘

Dear Mr. Sangston:

Wymvérymnhfwyummcent

letter-regarding

advance copies of the Canpaehmive Textbook 05 Pbtjdmy
by Freedman and Kaplan. I am writing to request a chmge
in my address of record from Bayview Avenue to 39 Arleigh Rd. ,
Great Neck, New York 1102]..
Thank ycu var-y

mch.
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

MP:kp

�</text>
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                    <text>August 31, 1967

Br.

Kar1 Ricke1s

1

=University of Pennsy1vania
Sahoai of Medicine
Dapartment of Psychiatry
Univarsity Hospita1
Phi1adeiphia. Pennsylvania 19104
LDear Kar1,

Enciosed

is

a Suggested

1etter to

be

sent to MIMH. I think
not be surprised if

site visit want very wel1. but
they'recammand approva1 with only one technician-and without
the EEG machine. ﬂeverthe1ess. I think you shou1d request the
EEG and if it turns out that they disapprove, perhaps we shou1d
then review aiternate ways of linancing.
the

wou1d

I am enc1osing a copy of my order and the
wi11 be the basis for your 1etter.

prices

think we wi11 be in business during the winter and
forward to setting up this program. My best regards.
I

A

which

Sincere1y yours,ﬂax Fink, M.D.

Professor of P’ychiatry

Mszp
enc .

-'

I 100k

�"w --

we»

-

~

mm

r-I ~:v-v-

mrw.»

ﬁrwﬂr‘hn‘wwﬁ'i‘ 'W'Wmn‘rlw. meiﬁiiz”

"awe-rur-

.

»~‘-W-7-:='

,

.

..

,

-.

.

‘Vunu‘n‘VW-v

v

v

~u;-

-

zu-

I'v’lfijw

“

'4'!

“any..."

.K—d‘y'waa-'

1”,;1-‘&gt;;"'l’¢ﬂ'-I‘W''4'51“

"mat-mm” .-

vrrntfrI‘VEVJIM‘Iiu-nwr-v'vn'xswﬂimw

§HGGESTEDiLETTEkz

August 31, 1967
'

'

,Dr, Jerome Levine
Assistant Chief

Psychopharmacology Service Branch
Bethesda, Maryland
NIMH,

'Dear Dr. Levine:

1

Re:

Supplement

MH—

089W

In establishing the budget request of the supplement to
three items were omitted that Should be considered
Committee
and if the grant be approved we ask the budget
the
by
be modified to inc1ude these items.
’1. Magnetic tapes are required to send

MH-08958,

‘

data to

tapes at

$30

For adequate switching between
.~tape recorder, a device may be

EEG

‘

New York ~ 40

for 800 records.
_A similar number will be required in
the second year.
each will be adequate

A

2.

to the specific-etions set

and Shapiro by

K

&amp;

While

it

built

Drs

Fink
5 Instruments of

St. Louis, for $400
3;

and

was planned

by
,

to use the available

EEG at Philadelphia General Hospital
-Drs. Fink and Shapiro have become concerned
that the amplifier characteristics of
different instruments would interfere in
any comparisons of population samples.
'

between

Y

,..

n.”

1;.q—w-m...m.-,,.&lt;

institutions.

For uniformity,

they are asking that each of the
participating grantees use Grass Polygraph
79511 EEG

amplifiers.

If at all possible,

such instruments should be provided and
are available a5»a 4 channel instrument
in an 8 channel chassis for $4500;

‘

He request additional equipment of $4500 and Supplies of
$1600 in the first year. and additional supplies in the amount
of $1200 in the second year. A revised tudoet is attached.
J

Sincerely yours,
Karl Rickels, H.G.

'

7..

mayu..mw,~,r,.,m,..,.v,..‘mﬁ_

�m
Lurk-m

:
Mite-‘1.'"5‘.~."'.

Grass Model 78

Ln”

g“

1

8 channei console 7A16P40.25

$

825.00

new

a
-

.‘

67RPS-A poker supply

800.00

Signal Marker

155.00

MT7A

Jab—44m:

66

oscillcgraphs

($140 each)

560.00

amplifiers

($400 each)

1600.00

7P511

78E320~8 thumbnail

eiectrode board

selector

and accessories

400.00

‘Wlswo
um.
$¢500.00

:ﬁ’4x«-_m’i’ngx.n
w

-—

y
in

�:wnr mm:— wmm-

V

L

,

August 31, 1967

TRIP RAIL FARE Great Neck~Ph1ladelphia-sreatﬂeck

ROUND

$

19.00

‘

Taxi

2.25

,

Lunch

1.50

.

$

Fink, M.D.
Arleigh Road
Great Neck, New
Max

39

York 11021

22.75

�</text>
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                    <text>August 28. 1957
Mr.

Stefan

Began

Research Associate

‘

Division of Medicai Affairs
Haffmann«LaRoche, Inc.
Nutiey, New Jersey 07110
Dear Mr. Began:
Thank yau very much for the suppiy 0f Librium, 25 mg,
5, 000 capsules which was received.
We are undertaking a study and
the distribution of this drug.
We

we

will keep records of

are grateful for your cooperation.
Sincereiy yours.
Fink, H.D.
Professor of Psychiatry

Max

�</text>
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                    <text>August 28. 1967
Dr. Turan

M.

It11‘

Missouri Institute of Psychiatry
5400 Arsenal Street
St. Louis, Missouri 63111
Dear Turnn,
Enc1osed are two copies of the EEG paper as read at the
and as rejected by the Amenican Jouhnal 05 Pagehiazny.
These are for ycur f11es.

APA

_

I do not know if you want to send it to anyone e1se,
since the essential mater1a1 w111 appear in the book by
Laska and K11ne, but we can discuss it the next time we meet.
.

Sincere1y yours.

Fink, M.D.
Professor of Psychiatry

Max

Mszp

1:.

“1:1

mw-unmm

mam»:

‘

�</text>
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                    <text>August 22, 1967
Dr. Burtzun C. Schiele

Professor of Psychiatry

Department of Psychiatry

8

Naumlogy

University of Iﬁmesota Medical School

Iﬁmeapolis, Minnesota

551455

Dear Burt,
Thank you very much for the slides of Istanbul. I have
them
had
mpied and I am most grateful that you have given me
an opportunity to augnent my slide collection. As I told you
before , I very much enjoyed your travelogue.

Again,

my

thanks .
Sinoemly yours ,
Fink, M.D.
Professor of Psychiatry

Max

Mszp

�</text>
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                    <text>E

E

E

E

August 22, 1967

z

Dr. Werner P. Koella

Senior Scientist

for fbcperimental 35.01qu
Shrewsbury, E'ﬁassachusetts 015%

The Worcester Foundation

Dear Wemr,

for your letter of August 17 , suggesting
2'1ave already clone so by
reservations for San Juan.
sending in the form requested to Dr. wittenhom. 2~Ieverthelesss,
I have submitted another reservation t0 him.
rthank you very much

that I

make

I look forward to seeing

you then.

Sincerely yours ,
Fink, Mi).
Professor of Psychiatry

Max

“‘2‘

a,

�</text>
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                    <text>August 22 , 1967
Mr. Alan Billig
E'Loffmarm-La Roche

Inc.
lﬁngsland
Nutley, New Jersey 07110
3H0

Dear Mr.

Billig:

Thank you very much for your willingness to support our
study program. As I had mentimed to you in my office, we have
been using Libriwn for the past four months in the psychophannacology

study program in the Mental Health Clinic as a stardard in the treat-—
anxiety. We would be grateful to receive 5,000 capsules of

ment of

Libriwn, 25

mg

eadl.

We'have been treatimg cases of anxiety in the clinic and
fave used Libriwn as one of the standard medications. I believe
that this is the best way t9 train our resident physicians in
the proper treatment of the acute mentally ill.
Thank you very much

for your assistance in this program.
Sincerely yams ,

'

Fink, 91.1“).
Prufeesor of Psychia

Max

V

�</text>
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                    <text>.r

August

mu‘wmavvf’vﬂvwmmwmv—WW‘SY

.

a

.

Dr.Char1eeJ. Dmn, Jr.'
Associate Medical Director

Ehdo Laboratories , Inc.
1009 Stewart Avenue
Garden City, Mew York 11533

xv-

nemcuwrr/ur-w

2-2, 1967

A

‘

.

"

.

‘

,

Dear Dr. Dimm
Please entities the delay in answering your letter of July 6
butthe mlidays intervened
and I was mt able to review the data
on Pblindone‘ until this week. I found Dr. Sugerman' 3 report of
great interest and believe that a
study with a standard
drug
antipsychotic
is probably meded at present.
Unfortunately, we do not have a population at Metropolitan
PbSpital suitable for such a study.
For this reason, I warm suggest met ycm content my former
associate, Dr. Man Itil, at the Missouri Institute of Psychiatry.
he has studied a nmnbsr of novel cozxpourxis using both clinical and
rs; analyses am has available to him a population of severe mentally
ill. I am taking the liberty of sending him a carbon of “CD18 letter
in the hope that this willexpedite yorxr mamioation with him, if
-~

Wave

"

,4

'

,

j

youwish.

Tim

.

on

this

you very such

oompc‘xmd.

,.

for the opportunity to read the literature
Sincerely yours,
Mex
_

(311C

Wm

.r-v'wn‘n

A

t
.

Trvsmm‘

1

‘,Fink M D.

Professor of Psychiatry

�</text>
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                    <text>W‘rmn‘n-"PWMW l'wr-V» w‘M-W‘

~mxmnm-

August 22 , 1957
Dr. Joseph G. Bird

Director, Division of Clinical Research
Sterling-Winthrop Research Institute

Ramselaer,

New

York 121M

Dear Joe,
The study of cyclazocine in the Mental Health Clinic has
been going very well and I am writing to request an additional
supply of cyhlazocim. Wand you please send 200 bottles of
cyclazocine 0.25 mgm (50 tablets per bottle).
Tharﬁc you

very mch.
Sincerely yams ,
Fink, M.D.
Professor of Psychiatry

Max

Mftkp

,

�</text>
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                    <text>ia

1§

1

i

i

2i

%

WW...me

-

mm-..

,

W,

August 22 , 1967
Dr. Roscoe B. Doughty
Smith Kline S French Laboratories
1500 Spring Garden Street

Welphia

1, Pennsylvania

Dear Dr. Doughty:

It was a
on Thursday. This

you and
pleam to have
I received

mung

am

New
5
-

me

Yam Medical College

is:

‘

East 102nd Street

New

York,

New

York 10029

I look fonaard to hearing from you.
Sincerely yours ,
Fink, NJ).
Professor of Psychiatxy

Max

Mszp

1'4,

writing simply tn indicate

Dr. Max Fink
Dapar'tment of Psychiatry

'

'

visit

letter'of August

WW

oonfiming your appointment and I
that the pmper address for your
3

Dr. Hoppe

yam

�</text>
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                    <text>August 21, 1967
Mr. Gene Kattmann
K 8 8 Instruments
1557 Reale

St. Louis, Missouri

63138

Dear Gene,
Thank you very much

laboratory. Everything

am

delighted.

have

Ybur

filed

bill

it

was quite modest and I am.most grateful.
and you should be paid very shortly.

Incidentally,

ticket,
to me.

far your help in setting up tha EEG
is running very well this week and H

it

Again,

would be
my

if

you

still

have the receipt

useful far our recards

if you

I

for the airline
could send that

thanks.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry

Max

MRKP

�</text>
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                    <text>August 21, 1967

We. Helen

Donovan
9303 68th Avenue

Forest Hills,

New

York 11375

Dear Helen,

is

and

girls are working out rather well. The laboratory
functiorﬁng with everything connected with everything else
is a great show. Would you like to visit sane afternoon?

Your two

now

it

Enclosed

help.

My

is a small token of my appreciation for your great

best regards .
Sincerely yours ,
Fink, M.D.
Professor of Psychiatry

Max

Mszp
enc .

�</text>
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                    <text>August 21, 1967
Dr. Warren A. 'I'hwtpam

Missouri Institute of Psychiatry
51400 Arsenal Street
St. Louis, Miami 63189
Dear War-pen,

for sending me the copies of the Articles
of Incorporation of the Foundation. These have been most helpfulin assisting me in establishing a similar fourﬂation in New York.
Thank you very much

Enclosed

sent to

me

Again

is

a.

statement directed to the HIP which has been

in ermr.

my

thanks .
Sincerely yours ,
Fink, MA).
Professor of Psychiatry

Max

�</text>
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                    <text>-wvwm

mun—W...»

.

«

ww-

,
m-

rr—vnr‘wn—r.»

..
‘1.

VFW-“WW

August 21, 1967

2r

1-!«rwzrww-r

Dr. William R. Tabor

A.ﬁ.&amp;mhmtbmmmr
1407 Cummings Drive

Richmond, Virginia 23220

Dear

Bill,
Enclosed are the Statement of Investigator Foam

FD

1573,

my

curriculum vitae, and a study protocol for an open study of
fenfluramine in volunteer subjects.‘ Ae-I had indicated to you;
the EEG patterns were so much like barbiturate that the state—
ment that fenfluramine is an anorexigenic agent is surprising;
'

For this reason, I would like to undertake a small Clinical
study in volunteers to see for myself whether these subjects do;
report weight loss and which behaViorel-effects, if any, accompany
such a change.

'

.

,

lhe data indicates that dosages of NO to 80 mg per day seem
appropriate and I will provide each of the subjects with a flexible
dosage schedule.

‘

'

.

As for supplies, I estimate the total study will take 1000
capsules of 20 mg each. However, an initial supply of 300 capsules
of fenfluramine 20 mg and 300 placebo capsules would be enough for

a Start .

Thank you very much

,

'

'

fortyour cooperation.
Sincerely yours,
Max

Fm,

MEL),

Professor of Psychiatry

�</text>
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                    <text>August 18 , 1987
Dr. Rioham P. Write

Asoociate Professor
The University of Tennessee

Department of Woology
waphis, Tennessee 38103
Dear Dick,

Thank you for your lottor of August 8 , which I have discussed
with the Ibcemtive Mndnistmtor of the lhpartxmnt of Psychiatry,
Mr. Irwin Schwartz. He will make available the funds. from our NIMH
grant for this study and will requim no additional special form
than those that are wormed by your University.

For

this reason,

we

maid prefer that your administration set

letter Mich means necessary to

them since our only require»
invoices approved by yoxmself and approved by me.
Tnase should involve the usual transferable items of persorml ,
consumable supplies and mutation.
up

a

mam: would be

If you will

send the

amninistratw Sign

it.

letter you

suggest to me, I will have our

Sincerely yomrs

,.

Fink, $74.1).
Professor of Psychiatry

Max

�</text>
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                    <text>August 17, 1967
Dr. Matthew- Brody
41 Eastern 13me
Brooklyn, New Ycrk 11238

Dear Matt,
Ehcloséd

for the

is

an abstract of the proposed presentation

1868 meeting; of tha New York State Medical Society.
Thank you vezy much for 37mm invitation and I look fgrwam

to mﬁdng with you.

Sincerely

ym ,

Fink, Md).
Professor of Psychiatry

Max
MP : kpl
CHIC o

�</text>
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                    <text>August 18, 1967

National Instituta of Mental Health
Public Health Service
Bethesda, Maryland

Gentlm :
May I please have two applications
Service Grants (PHS~398).

far Public Health

Thank you.

Sincerely yours,
Fink, M.D.
ProfEssor of Psychiatry

Max

mfﬁqa

�</text>
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                    <text>�Dr. Sanseigne

‘

a2-

These cmzplaints are picayune

I can only agree with the data
.

Turan called

Istanbul.

me

.

.

&gt;

August 15, 1967‘

but, except tbese omnts,»

and oonclusibns.

and medial discuss bigh‘ dose study

is

in

so important as to provide any difficulty
for any of our friends and I do hope that our encowagerrent of
this program has not anbmessed you: in any Way. We will
probably. help the Tlmkish paychiat-rists mdervtake such a study,
if we can obtain the supplies for than.

-

No

study

,

In the ,nwanwhile, our study in New York is going well and
row, to our dmgr‘in, tint Many of the arbulatory patients
who were apparently doing well on ﬁnalmged phenothiazine mdioatim,
have been doing just as well On plaeebo! We have many ﬁbre patients
in our stMy group thanhave reoeived flupbenazine decanoate. But I
.

we

have

am

sure the {timbers will: morease..

'

Many

‘

My

thanks for, the opportlmity to see the
'Sineerfely yours ,
‘

‘7

MFEkp

..

o'T'Tv‘P'i‘J"

.-y

w-.

..Wur\

demate swarms.

best personal regards.

,'

Fink; M.D.
,
Professor of Psychiatry

Max

�</text>
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                    <text>J-

-

‘

,y»'WIvH-rqw(wﬂzmzrm‘

y

mar

August 15, 1%?

.

mrvngw-r-wvw

1!"!

man-n

Mgr'fx-JWWANFF

Dr. Turan

Itil

Dear Turan,

I found these: tables in

am"

.._«mvn.-,,,M

M.

Missouri Institute of Psychiatry
SHOO Maria]. Street
St. Donia, Missouri 53139

Look at Table 14 camfully and
has; been available since 1959

lparine in
My

its

use!

one of the "him away journals.
note that Squibb fluphenazine
at Boston State and is next to

best regards.
Sincerely yours ',

,-

n20!

Fink, NJ).
Professor of Psychiatry

Max

Lgﬂﬂﬁ'ymwvwayuvvllﬂllw‘)

a

.,

.,..‘

Mszzp

.-,

v

__.,

.

5..

.:\uu,_.,nm,-,¢§,3V~r7mu1;5,,.v1”‘3‘,

wwu'ww‘r'

warm-1‘

:0!»

u

~‘

xm2:n..

,

a

cc: Dr. Sanseigm

�</text>
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                    <text>-—

I-‘v'x‘n'n'm‘riwx

v"

«wig-a

WKYWP-"m‘wm'mm'wrnwrn'vﬂWn—w

.

August 15, 1967
.

Secretariat

IBRO

UNESCO

2

i

House

Place de antenqy

Paris 7, France
Gentleman:
White

I am.writing in support of the application of
fbr support for trayel funds to Enable him t0

Dr. Philip Bradley in Binningham, England.

‘.

I have known Of Dr. White's work far-many years, based on
interest in the electrophysiological effects of anti~

-

our

Dr. Richard P.
work with

common

'

cholinergic hallucinogens. Dr. Whites' studiés are among the
best controlled and most carefully done which have been recorded
in this difficult field. .On two occasions I have had the pleasuvev
of calling on him ta participate in international symposia and
haye fbund his contributionsiunusually rawarding.‘
Dri White's interest in extending his technidues by
working with Dr. Bradley, whg is another‘outstanding leader in
this field, is to his credit ang I'wuuld encourage the Committee
to make every effort to provide him.with the funds necessary to

'

w

‘

undertake this study program;

*‘

"-

',

Sincerelyvyoufa,“

”

MF:kp
‘

cc; Dr. Whita

Max Fink

24.13.
_
Prefessor of Pﬁychiatry

-

�</text>
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                    <text>must

1n , 1967

Dr. Michael C. Barry

Assistant Medical Director
White Laboratories , Inc.

Kenilmrth,

New

Jersey

DearDr. Barry:
Some

weeks ago you

visited my laboratory

and we discussed

the possibility of a high dose and very high dose fluphenazine
study program, to be mderrtaken at the University of Istanbul.
My associate, Dr. Itil, has sent you sane of the references

whichyouroquestedandhasaskedmtosendyouaoopyofthe
revised protocol, which is enclosed.
Tim you for your consideration.

Sincerely ywrs ,
Fink, M.D.
Profassor of Payohiatry

Max

MF:kp

'

.

,

“.uvmrv‘mr'um'z‘.

�</text>
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