4
100
6429
-
http://exhibits.library.stonybrook.edu/mfp/files/original/05e294aa7fa75d2de3cca37d48e3104d.pdf
051ac52b06f0e897b637551b22dbe70a
PDF Text
Text
June 13, 1983
Tom G. Bolwig, M.D.
Rigshospitalet
9 Blegsdamvej
DK-ZlOO Copenhagen (0
Denmark
Dear Tom,
It was a pleasure to meet you in New York; and I thank
for your kind
comments about my convulsive therapy history. I have sent a draftyou
the
to
American
Journal of Psychiatry for their consideration.
It is difficult to know what to make about
your announcement about the
electrotherapy group headed by Gary Aden. They are well meaning and well funded,
and they could encourage a better image for ECT, but their
commitment to legal
defense and maintaining present practices made me uncomfortable.
There is still a
need for a reasoned voice in defense of ECT when confused
a
community
reacts
with anger; hopefully, the American Psychiatric Association will
establish
a
committee for such a purpose.
I am unable to come to Vienna for
the World Congress meetings, as I have
family matters which need my attention. Let me know what happens
in the ECT
and EEG sessions.
My best regards.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-4-104
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1983
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http://exhibits.library.stonybrook.edu/mfp/files/original/7e5d8de6e5dc11968b5ef98cc490e76b.pdf
55430bd86540f8acf0d08dab0bd6c229
PDF Text
Text
-‘
Mww
.r
.
June 14, 1983
Barry M. Maletzky, M.D.
8332 5.13. 13
Street
Portland, Oregon 97202
Dear Barry,
Thank you for your letter of May 27 regarding an ECT journal or
newsletter.
Following Paul Blachly’s death, I considered continuing the Bulletin, but
the burden seemed too great and the need small. In the past two years, however,
the need has become greater, and I have looked into the question.
believe that there is little future for a journal dedicated to ECT alone. i
have approached some publishers, and each indicated, correctly I believe, that a
journal dedicated to one treatment would have a limited audience. More important,
it would not attract the best papers. The better authors and best papers would be
sent to the general journals, since there they would get the widest circulation. I
also enquired about an ECT section in a major journal, and four editors turned me
down; again, I can agree with their logic. They accept articles about ECT, and if
we made a dedicated section, we might get to use fillers with a negative impact on
I
quality.
‘
newsletter is another matter. I have approached three publishers and I
have prepared a prospectus for two of them. i propose a newsletter along the lines
of the Biological Therapies Newsletter, dedicated to the technical and scientific
issues of convulsive therapy. If I am successful in getting the funding, the first
issue will be out before the end of the year.
A
My
regards.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-4-103
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1983
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/d6297c1d5c48b7ef71aea40a6daeabb3.pdf
847ab47c4f14ad8fa597711e295964e0
PDF Text
Text
June 13, 1983
Marvin Stein, M.D.
Department of Psychiatry
Mount Sinai Medical Center
One Gustave Levy Place
New York City 10029
Dear Marv,
When last we met, in the foyer of the Sheraton Centre during the APA
meetings, you indicted that your committee would consider the formation of a subcommittee to deal with the day-to-day issues regarding convulsive therapy. Was a
decision made ?
My
regards.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-4-102
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1983
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http://exhibits.library.stonybrook.edu/mfp/files/original/f316ddf83e69ddf878ff80a44bf9ce67.pdf
83f5c3da551c9fe4849a75ec2d19d8bb
PDF Text
Text
June 27, 1983
Francis M. Daignault, M.D.
Mercy Medical Plaza -Suite
15116 Jackson Road
10
9.0. Box 1127
Ann Arbor, Mlchigan 48106
Dear Dr. Daignault,
There are very few good films of the ECT process, and I know of none
that are very useful for families of patients. One videotape is available from the
manufacturers of MECTA (Mrs. R. Nicol, MECTA Corporation, 122 SE 8th Avenue,
503-231 2808). It was made by Dr. Barry Maletzky of
Portland OR 97214
Portland, Oregon, and gives undue emphasis to MMECT, but it is otherwise
-
acceptable.
Another was made a few years ago by Dr. Richard Abrams (Department of
Psychiatry, Chicago Medical School, V.A. HOSpital, North Chicago, Illinois 6006#
312-578 3330). It is a good presentation for students, but I am not sure it is good
for relatives of patients.
——
There is a need for a technically well presented videotape which may be
useful for students, patients, and their families. If you have the skill to produce
one, it will be in demand.
Good luck.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
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mfp-05-00-030-4-100
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1983
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http://exhibits.library.stonybrook.edu/mfp/files/original/0d4dc22d831f4ac277ebd1d87989bb1b.pdf
5428c7ad41f4b1cc14c3351ff55787cb
PDF Text
Text
June 27, 1983
Mr. Mark Robertson
BlackwellScientific Publications
99 Barry Street
Carlton, Victoria,
A
UST R A LIA
3053
Dear Mr. Robertson,
volume, "Handbook of Affective Disorders" edited
chapter on convulsive therapy
it,
"Handbook of Studies on
Burrows
in
which is clearly a re-hash of his earlier chapter
Dr.
Kilbh
citations
has no
after 1978, omitting
Depression". In the newer chapter,
would hope that his
One
few
years.
some interesting contributions in the past
would
reflect the present state of the art, including
contribution to the new volume
the reviews by the American Psychiatric Association (1978), Fink (1979), and the
Britidn arguments reflected in reports by the Royal College of Psychiatrists (1977),
Pippard and Ellen (1981), and Palmer (1981).
'
I have 3131: received the
by Prof. E. S. Paykel. In
Prof“. Kiloh has a credible
is of some help to the development of a better book
objection to your sharing these com menm with the authors.
If it
I have
Sincerely yours,
Max Fink, M.D.
meeaor of Psychiatry
no
�
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mfp-05-00-030-4-099
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1983
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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-
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43cc25ef049c4657e724650afa6c7a79
PDF Text
Text
.\\
'
June 28, 1983
Carolyn B. Robinowitz, MD.
Director, Office of Education
American Psychiatric Association
1400 K Street, NW.
Washington, D.C. 20005
Dear Dr. Robinowitz,
Enclosed is a draft copy of my remarks at the recent meeting of the
A.P.A. I have urged, for some time, the A.P.A. leadership to accept responsibility
for encouraging teaching and the optimal use of convulsive therapy. The events in
California, leading to an interdiction of its use in one community, reflects the
persistent poor press that psychiatry enjoys.
But part of the responsibility for this press is our own -- and one aspect
was discussed by the 1978 Task Force on Electroconvulsive Therapy in their report.
The committee, under Fred Frankel, did recommend a continuing committee of the
A.P.A. with a mission to serve the Association's members, to improve teaching and
education, and to answer queries by the public. Unfortunately, none of the
recommendations of the TAsk Force have been implemented.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-4-098
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1983
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54a9740d6c04025c3ef1a91dae05ab13
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August 8, 1983
Ira Sherwin, M.D.
EAEEG, Inc.
200 Springs Road
Bedford, Massachusetts 01730
Dear Dr. Sherwin,
Thank you for your kind invitation to present a paper on EEG and
psychoactive drugs at the March, 1984 EAEEG ski meeting. I would like to attend
but prior committments will prevent it.
In my stead, you may wish to invite Jan Volavka, M.D. (Research Division,
Manhattan Psychiatric Center, Ward's Island, New York) or Mr. Peter Irwin
(Medical Department, Sandoz AG, Basle, Switzerland) -- two of my former coworkers who are capable of making a fine presentation. (Mr. Irwin will be back in
the States this Fall).
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-4-097
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1983
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06f7d67149c2cf63f77c465a8cc30d79
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August 8, 1983
Dr. Richard D. Snyder
140 Hickory Hills Place #3
Charleston, West Virginia 25314
Dear Dr. Snyder,
Thank you for your invitation to collaborate in developing computer
programs. The experience I had with Milliken was pleasant, but the work was
arduous and rather mechanical for my way of thinking. I do not relish another such
exercise. I also regret that I do not have a copy of the printout for the Milliken
program. They supplied me with a disk but after testing it on an Apple computer, I
put it aside, since I do not have an Apple of my own.
Good luck in your programming.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-4-096
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1983
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a78703aaf22f24b5d8ab202583b135fc
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August 5, 1983
Dr. Steven Harnad, Editor
Behavioral and Brain Sciences
Suite 240
20 Nassau
Street
Princeton, New Jersey 08540
Dear Dr. Harnad,
in reply to your
letter of July 27::
1. Changing substantive to substantial in paragraphs 2 and 3 of my comment on
Weiner's article does not change the sense of my discussion and the comment may
stand.
2. Squire and his associates have presented numerous reports on the effects of
bilateral and unilateral ECT on memory functions. I do not believe a reference is
needed, since Weiner has already given the important ones. But if you believe it
helpful, add:
Squire, L.R. and Slater, P.C. Electroconvulsive therapy and complaints of
memory dysfunction: A prospective three-year follow-up study. gr. J. Psychiat.
_l__lg_2_:
1-8, 1983.
3. The suggestions for changes in consent procedures which Weiner makes were
made by the APA Task Force. He is repeating what is already in the record,
perhaps with less attribution than is deserved. The suggestions in the consent were
published by the APA Task Force in 1978 and in my book, 1979. The APA book was
published in November, 1978.
4. Roueche, B. Annals of medicine: as empty as Eve. New Yorker 2Q: Sit-100, Sep.
9, 1974.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-4-095
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1983
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September 9,
19 83
Gregory Teas, M.D.
Alexian Brothers Medical Center
800 West Biesterfield Road
Elk Grove Village, IL 60007
Dear Dr. Teas,
The established recommendations for ECT are those that have been
published by the APA Task Force on Electroconvulsive Therapy (1978). There are
other guidelines in my book (Fink, M.: Convulsive Therapy: Theory and Practice,
Raven Press, New York, 1979) and a recent British manual (Fraser, M.: _E_(_3_T_: _A_
Clinical Guide, John Wiley, New York, 1982). Unfortunately, none answer your
questions for maintenance ECT or out-patient ECT.
it is generally assumed that courses of ECT will begin in a hospital
setting, where a pre-treatment spine x-ray and ECG are recommended. There are
no ‘laboratory' tests that are prerequisite to a course of ECT, although all guides
suggest that a medical 'clearance' be obtained, and presumably this will include
such routine laboratory tests as CBC, urinalysis, and SMA 12.
During a course of ECT, ECG records are often repeated if the patient's
medical condition warrants — where cardiovascular disease is pre-existent and
where the treatments are marked by cardiovascular events. Spine x-rays are rarely
repeated but may be if the patient complains of back pain or it there is a
remarkably 'violent' treatment experience.
I
see no reason to change these guidelines for patients maintained on
treatments at home.
For a more definitive answer, I suggest you address your request to Melvin
Sabshin, M.D., the Medical Director of the APA. It was the recommendation of the
APA Task Force that a permanent committee on ECT be maintained by the APA to
answer inquiries such as yours. If enough members write with their questions,
perhaps this recommendation will be implemented.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
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October 3,
19 83
Dorson Liss, M.D.
Chairman, Special Procedures Committee
Good Samaritan Hospital
2425 Samaritan Drive
San Jose, California 9512!;
Dear Dr. Liss,
The literature on maintenance ECT is not reassuring. The principal studies
in my book on ECT (Pg 207). The APA Task Force was unable to find
detailed
are
satisfactory data to allow a recommendation, so reference to such studies was
included among the research needs in the Task Force Report.
This question has been asked by a number of other respondents. The best
suggestion that I was able to make reflected the present practice on my service at
University Hospital. About half our effectively ill patients who respond to a course
of ECT are discharged on maintenance drug therapy, usually imipramine, less often
lithium or phenelzine. When such patients relapse, and recover in a second course
of ECT, we then consider discharge on maintenance ECT, initially recommending
weekly treatments for 2 to 4 weeks, then bi-weekly for a month. We have not
treated a patient beyond 6 treatments as an out-patient, always trying a second
course of a maintenance drug trial. I am not satisfied with this experience, and did
propose a study which was not approved by granting agencies.
would be grateful for a copy of your recommendations when these are
adopted at your hospital.
I
Thank you for your inquiry.
Sincerely yours,
Professor of Psychiatry
�
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1983
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75m“;
October 6, 1983
Dr. Ian Brockington
Department of Psychiatry
University of Birmingham
Queen Elizabeth Hospital
Birmingham B15 2TH
Great Britain
Dear Ian,
Thank you for the address of Professor J.A. Hamilton. Dr. JoAnn Woodie
is the member of our staff most interested in the psychiatric problems associated
with pregnancy, and I have given her his name, with the suggestion that she write
to him.
As best as I recall the Hinckley affair, he was acquitted of attempted
murder by reason of insanity, on the advice of a number of defense witnesses,
among whom was William Carpenter. My only connection with the affair was
through reading the New York Times. A search for reports of the Hinckley trial in
the New York Times index for 1981-1982 should give the articles which describe
the testimony.
And, thank you for your invitation.
come to England.
My
I
shall keep it in mind when next
-
regards.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
I
�
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Department of Psychiatry and Behavioral Science
Health Sciences Center
State University of New York at Stony Brook
Stony Brook, New York 11794
telephone: (516) 4442990
StonyBrook
'
October 7, 1983
Dr. C. P. L. Freeman
Senior LeCturer in Psychiatry
University Department of Psychiatry
Royal Edinburgh Hospital
Morningside Park
Edinburgh EH10 5HF
Great Britain
DCarDrr-Freeman.
..
-»
_
7
-
»;
r' ."monthTedrd“revrew-“theteachingew-vMauwwactivities in ECTin this country. I have organized a workshop at the next meeting
of the American College of Neuropsychopharmacology (December 13,1983;Caribe
“
'
Hilton Hotel, San Juan, Puerto Rico). The session is focussed on similarities of
biochemical measures in ECT (and ECS) and antidepressant drugs.
At the 1983 meeting of the Society of Biological Psychiatry meeting, I gave a
special address on the history of convulsive .theraP)’, anticipating the 50th
anniversary on January 2#,'1984. The next president of the Society, Dr. SarwerFoner plans another special lecture be given at the 1984 meeting, to be held in San
Francisco in May. He has invited Professor Jan-Otto Ottosson to review the history
of theories of the mode of action of convulsive therapy.
Each year, at meetings of the American Psychiatric Association, we have
held a panel on clinical issues The sessions have been organized by different
leaders (Trevor Price of Dartmouth University and Richard Weiner of Duke
University in 1983). I do not know what is planned for May, 1984 in San Francisco. I
believe that Trevor Price and Ari Albala (University of Michigan) are planning a
teaching workshop. There is usually room for volunteered papers, either in the
regular program, or in the special sessions of the Society of Biological Psychiatry.
The section of psychiatry of the New York Academy of Medicine is
organizing a special 50th anniversary meeting on ECT on February 2, 1984. Richard
Abrams, Fred Frankel, Lothar Kalinowsky, Sidney Malitz, and Iare among the
invited speakers.
This is the schedule of meetings, as far as I know it. There is nothing
scheduled for November, 198# that should be in conflict with your program. If you
are interested in coming to the U.S., let me know when you believe your data will
be in good shape, and I will try to recommend an appropriate forum.
�Dr. C.P.L. Freeman
'
_
October 7, 1983
Page
2
talking with Dr. Crammer, in reply to my question regarding texts for
that you had written a manual for ECT, published and distributed by
Smith Kline 6: French Laboratories. He did not have a copy, nor was one available
at the Maudsley Institute of Psychiatry library. 15 it available in the US. ? If not,
how can I get a copy ?
In
ECT, he said
The furor about ECT is now muted, and more and more, I find the medical
and lay communities approaching the use of ECT with a reasonable, questioning,
attitude. There is more research interest, both by clinicians and basic scientists,
and we are optimistic that research funding will be available without the thorny
issue of ethics muddying the review process. Our principal concerns are not the
electricity/seizure issue, but the efficacy of unilateral electrode placements and
brief pulse stimuli. The Royal College report by Pippard and Ellam has been very
helpful, in suggesting that usage in the US. is not (relatively) excessive, and that
technical questions, particularly the monitoring of seizures, need special attention.
Thankfyouforjyour letter, and my best regards.
Sincerely yours,
744%
Max Fink, M.D.
Professor of Psychiatry
�
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w
-
"mix"
October 17, 1983
Billy E. Jones, M.D., Director
Department of Psychiatry
Lincoln Hospital
234 East 149 Street
Bronx, New York 10451
Dear Dr. Jones,
I regert that I am unable to accept your kind invitation to present a
lecture to the staff of Lincoln Hospital. I will be unavailable on the date selected.
I recall with pleasure the lecture I gave in 1980, and the interest of the
staff in so controversial a topic as convulsive therapy.
My best wishes for your success
at the College.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-4-089
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1983
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October 25,
19 83
Dr. 3. Born
Laboratory for Neuroendocrinology
University of Ulm
Steinhbvelstr. 9
7900 Ulm/Donau
Germany
Dear Dr. Born,
In the program of the September meeting of the German EEG Society, I
found a listing of your report, "Eifekte eines ACTH (4-9) Analogs auf die EEGAktivitflt". We have studied the effects of this compound in volunteers and
patients, without establishing a clear pharmaco-EEG profile. I would be grateful
for a preprint of your report, if the results have been positive.
Thank you for your cooperation.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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November 1, 1983
Alick Elithorn M.D. FRCP
Department of Psychological Medicine
The Royal Free Hospital
Pond Street, Hampstead
London NW3 ZQG
United Kingdom
Dear Alick,
r
'ue’
The usage of ECT early in an illness, rather than as a last resort, has
become a reasonable tenet of our practice, based on the extensive evidence of the
efficacy and safety of ECT. When the California legislature, in 1973-1974, enacted
restrictive legislation against the use of 'intrusive treatments', including ECT, the
American Psychiatric Association appointed a Task Force (1975-1978) to review
the evidence of safety and efficacy of ECT, and to provide guidelines as to a
proper response to restrictive rules. The Task Force reviewed the literature,
carried out surveys of usage, held public hearings, and published a report (American
Psychiatric Association, Task Force Report #14, 1978). The members concluded
that the evidence for the efficacy of ECT in major depressive disorders and
catatonia was compelling; in mania, less well defined; and for schizophrenia, poor.
As for safety, the committee concluded that in its own right, ECT was remarkably
safe (when properly done) and in comparison with other treatments (as tricyclic
drugs and lithium, for example) as safe or safer. The Task Force also noted new
evidence that ECT was more effective than tricyclic drugs in treating delusional
depressions. Soon after that publication, articles appeared that indicated that ECT
treated patients had a lesser incidence of successful suicides and lesser death rates
from other causes when compared to depressed patients treated by other means.
-v
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In 1979, I published my book on ECT (Convulsive Therapy: Theory
and Practice. Raven Press, New York, 1979) in which I documented the same
information and concluded that ECT was particularly effective in severe
depressions and catatonia, especially if accompanied by delusions, inanition, or
suicidal drive. 1 suggested that the standard approach of using all other treatments
first, and reserving ECT for treatment failures, was contrary to the evidence, and
encouraged the earlier use of ECT.
After that publication, I became aware of the 1964 deCarolis study
(Avery and Lubrano: Am. J. Psychiat. l36z559-562, 1979) Which clearly showed the
efficacy of ECT in patients who failed adequate courses of imipramine therapy.
-
�Dr. Alick Elithorn
November 1, 1983
Page 2
Since then, others have come to similar conclusions about efficacy
and safety, notably Kendell (1981), Weiner (1981), and Palmer (1981).
There have been other supports of early usage. The awareness that
some elderly patients with symptoms of dementia may be suffering from severe
depression (which is responsive to ECT) has encouraged the early use of ECT in
elderly subjects (presumably suffering with 'pseudo-dementia'). Reports that
patients with a syndrome poorly classified as neither schizophrenia nor depression,
but rather 'schizo=affective disorders' are responsive to ECT is also encouraging.
We now teach that the severity of the illness is a compelling factor
in our choice of treatment. For severely depressed and delusional patients,
particularly those whose medical status is compromised (inanition, metabolic
disorder, cardiovascular decompensation, pregnancy), who are ill enough to be
hospitalized, ECT is considered among the initial treatment choices. I recommend
and use ECT as a primary condition in the most severely ill patients.
For severely depressed and suicidal patients, who have recently
carried out a severe threat, ECT is preferred.
In elderly patients with depressive conditions with symptoms of
dementia, ECT is clearly preferred.
in psychotic pregnant women, during the first trimester, who cannot
be managed by nursing care alone, ECT is preferred over antipsychotic,
antidepressant, or antimanic drugs.
None of this is stated as explicitly in one location. Indeed, since
publishing my book, and while on the lecture trail, the question has often been
asked. II'Gradually, especially when I am encouraged to see patients in case
conferences, I have become holder in my statements about the indications for ECT.
I have also been encouraged by a long line of successes with ECT in patients who
have failed other treatments, since 1 accepted responsibility for the therapy unit at
this hospital.
There is one other factor which operates here but may not in your
country. When, in 1976, I carried out a survey of usage of ECT in New York, I was
amazed to find greater usage in upper class, private pay hospitals. Clinicians in the
U.S., faced with a severely depressed individual requiring hospitalization, who when
well, was active in the home, office, or business, use ECT in preference to drugs
because they are convinced that the resolutions are more rapid. For hospitalized
patients, especially those whose insurance has a 30—day or [LS-day clause, ECT is
clearly the first choice. It is in our public mental hospitals, where the cost of care
is borne by the state, that duration of hospitalization is not a factor, and therapists
follow popular beliefs about the relative risk in ECT. (Many public hospitals also do
not provide ECT since it is labor intensive and therefore very expensive, requiring
psychiatrist, anesthesiologist, nurse, and aide.)
�Dr. Alick Elithorn
November 1, I983
Page 3
I am not sure what prompted
your question, but I chose to give a
detailed answer since it is an exercise which Ienjoy. In September, I attended the
advanced postgraduate sessions in psychiatry at the Maudsley Hospital. 1 was
impressed with the quality of care of the patients and the extent and fine quality
of their research endeavors. I was given a short tour of the ECT facility and in this
fine institution, usage was similar to that we see in our public mental hospitals. I
was reminded of the Pippard and Ellam report (which has had a good press in this
country) and the conclusion that in about 1/3 the centers, ECT was administered
poorly.
It is sad that this treatment, which has so much to offer so many, is
restricted to so few. In January, it will be 50 years since the first convulsive
treatment was given by Meduna in Budapest. Hopefully, our understanding of the
therapeutic process will improve so that the treatment will be less feared, and soon
replaced by a more acceptable treatment as our undersatanding of its mechanism
grows.
My
best regards.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-4-087
Date
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1983
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
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en-US
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Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/a203c21eb74806b4e25fd6fd24e8f0a5.pdf
930b7fe630a7a4bb2395d8a97324af5a
PDF Text
Text
November I, 1983
Mr. Peter Irwin
1m Hirsholm #6
11125 Riehen
Switzerland
Dear Peter,
Thank you for your letter of October 19. Receipt of the enclosed
reprint request stimulates me to answer today, and to bring you up to date with
happenings in New York.
Vojta called to invite me for dinner at his home, and then told me
that his large grant to study EEG's in prisoners was hung up in a political argument
whether biological studies of criminality were warranted since 'everyone knows
is socially determined'. When he called me initially about computer
I
him to use our system if he wished. I gave him the same caveat,
encouraged
use,
that IBM may stop support when we may need it most. (I did not demur as to its use
long as it is functioning, I am pleased to have it used, with charges consistent
-so
with the real expenses, usually nominal.) He told me that he had this large grant
and I suggested that, if the funds were available, he might wish to get the type of
system that you, John Pavel, and Don had recommended to me. By writing his own
programs, he should be able to get the outputs that would optimize any findings.
-—
that criminality
Your comments about the Neurometrics machine are consistent with
it, and I did not recommend that course of action.
my own image of
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7
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[Mr
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We are in the midst of a pharmaco—EEG study of a putative betablocker,
azepexole, and continuing our clinical explorations, recording
adrenergic
EEG's in patients during ECT, lithium, lithium plus haloperidol, lithium plus
carbamazepine, and propranolol therapies. So far, we are seeing 'neurotoxic'
effects with ECT and with lithium plus haloperidol, and these should prove
interesting when quantified.
We finally received approval for a nursing position within the
offered
it to Lynn Johnson, only to be rejected as she said that she
Department,
had a better paying job. I am very disappointed, since [could have hired a nurse in
April, at the same time as I put Linda and Emily on Research Foundation moneys.
In trying to work within the State system to assure her retirement funds, we have
lost more than six months in our clinical studies.
�Peter Irwin
November 1, 1983
Page 2
l expect Gabrielle to visit us next week for a few days. She is 93
route to her company offices-in New Jersey. The week after, Werner Herrmann is
visiting, and I look forward to a few days of pharmaco—EEG talk. Sure will miss
your pithy comments.
Congratulations on your membership in IPEG. I received a copy of
the 'official' membership list, and you are now an active member -- if I read the
German correctly. (Walter Sannita has written to me, asking whether I would
intercede on his behalf, for membership. Perhaps we will both have to write letters
for him.) I have heard nothing about a replacement for Dieter Bente, either in his
Universityy or in IPEG, but expect that I will know more after Werner visits.
My children are well. Jon is now busy visiting volcanoes in Oregon,
Hawaii, and lsrael. He has received an NSF grant to contrast findings in four
locations and he is enjoying doing the project.
i received another package of tulip bulbs from Holland, spent this
week-end
past
getting them into the ground. Lots of work -— and are my muscles
stiff today but well worth it in the Spring, if the results are as brilliant as we
had this past year.
-
My best to Barbara and the children.
Sincerely yours,
�
Dublin Core
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Correspondence to: Irwin, Peter
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mfp-05-00-030-4-086
Date
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1983
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
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en-US
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Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/962e85794ac4add28146ea374e64e3ce.pdf
5e80803a3a6bb58bc3fc46cf5e0f09b0
PDF Text
Text
..
_.
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.
.—
av
whammy
January 25, 1983
Prof. Dr. T. Vossenaar
Organon
Oss, Holland
Dear Jack,
1 have been in
touch with Roger Finder, and have arranged to visit 055 on
February 22/23, as part of my return trip from holidays in Israel. Martha and I will
be spending 10 days as tourists. She will leave for New York from Tel
Aviv,
however, as she has to get back to school, so she cannot visit this time.
u.
a“
“an“..-
Roger is making up my schedule.
opportunity to meet with you.
I
would be most pleased to have an
mwmw-nwww
My
best regards to the family.
.
.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-3-081
Date
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1983
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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en-US
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/e83cefffb7ad6fbe0bcb053b6cb6014d.pdf
578c0742472c9cc8ed6ddbcc74cbefaf
PDF Text
Text
r,
,
muwm~
January 25, 1983
Dr. Roger Pinder
Scientific Development Group
Organon
Oss, Holland
Dear Roger,
I have made reservations to arrive at Schiphol at 1550 on Tuesday
afternoon, February 22 on KLM 2%, after a 1445 departure from Frankfurt; and
also for the KLM 6‘53 flight to New York, departing Schiphol at 1700 on Wednesday
afternoon. (I can extend the latter for the next day, if that is useful for us.)
I would be grateful if you would arrange for a car and driver at Schiphol,
and for a hotel in 055 for Tuesday evening. 1 will leave the programme up to you.
Thank you for the recommendation regarding the mianserin meetings in
am scheduled to give a paper at the Society of Biological Psychiatry
sessions in New York on April 29 - May 1. l have asked the Program Committee
chairman to schedule the lecture during the latter two days, if possible.
Ireland.
I
My
best regards.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
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mfp-05-00-030-3-080
Date
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1983
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Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
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en-US
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application/pdf
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Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/711f28e20fa78875f8829888e0346a0d.pdf
5dd4c329816d58c64eb004395888f814
PDF Text
Text
November 15, 1982
Ms. Gabriele Kleindienst
Medizinische Abteilung
Hoechst Aktiengesellschaft
Postfach 80 03 20
6230 Frankfurt am Main 80
West Germany
Dear Gabriele,
Following our telephone discussions last week, we have begun a crossover
of
the EEG and behavioral effects of l—penbutolol at 100 mg and placebo in
study
12 normal male volunteers, following the specifications of the protocol dated
October 6, 1982, which we sent you on October 15. The data collection will require
about eight weeks; but because of the year-end holidays, these may not be
completed until January and the data analyses by late February.
enclose a draft of the sum mary report of our dose-ranging studies with _l_penbutolol. These data provide the basis for our recommendation for a placebo
controlled trial at 100 mg.
I
This assessment required 15 sessions, and I enclose a statement of our
reimbursable expenses in the amount of $3,630. Would please request a check be
sent us ?
For the placebo-crossover study, using the same budgetary allowances
(February 13, 1982) of $20/hour for experiments and $60/hour for computer time, I
suggest an allowance of $4,240.
My
best regards.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�January 28, 1983
Gabriele Kleindjenst
Medizirflsche Abteflung
Hoechst Aktisngeseflschaf‘t
Postfach 80 03 20
6230
am Main 80
West Germany
Ms.
mm
Dear Gabriele,
The artist's drawings for the Betapreasin report were done today, sooner
thanIexpected, solhasten to send a draft foryour-neview.
Ilook forward to seeing you on February 20.
My
baa: regards.
Sincerely yours,
Max Fink, M.D.
Profemor of Psychiatry
�'
"
«Va-wmm'
January 25, 1983
Ms. Gabriele Kleindienst
Medizinische Abteilung
Hoechst Aktiengesellschaft
Postfach 80 03 20
6230 Frankfurt am Main 80
West Germany
Dear Gabriele,
The penbutolol study report is now typed, lacking only the artist's
drawings for the draft to be sent to you. The EEG profile is clearly most similar to
that which we elicited for clonidine. We expect the figures to be ready by
February 4, and I will send a copy promptly.
have made reservations to fly from Tel Aviv on Sunday evening,
February 20, on Luithansa605 arriving in Frankfurt at 1950. I also have reserved a
flight to Amsterdam on Tuesday afternoon, February 22 at 1445 on KLM 21m.
I
Thank you for your and Dr. Grigoleit‘s letter of January 17. I shall
continue to do whatever I can to assist you in your studies and in developing the
pharmaco-EEG program at Hoechst. Reimbursement for services rendered are
acceptable, although probably more expensive for you than on a consulting basis.
Reimbursement for the direct costs of studies (volunteer fees, technicians, gig.)
and for travel are billed as expended. The consultation fee for the design and
implementation of a pharmaco-EEG study is $5,000. Hourly charges vary with locus
in New York, $100 and abroad, $150, with a daily basis of $800 in New York and
$1,200 abroad.
-
I
trust this is acceptable.
My
best regards.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
Dublin Core
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Title
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Title
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Correspondence to: Kleindienst, Gabriele
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mfp-05-00-030-3-079
Date
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1983
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
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en-US
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application/pdf
Publisher
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Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/1a54b88d1c34a9e9d616bc7be771b1e4.pdf
b98d3a3e5e5b1a2184f76de95ffd4fbf
PDF Text
Text
February 3, 1983
Ms. Gabriele Kieindienst
Medizinische Abteiiung
Hoechst Aktiengeseiischaft
Postfach 80 03 20
6230 Frankfurt am Main 80
West Germany
Dear Gabriele,
Thank you for your letter of January 20, describing the arrangements for
visit
on
February 20/22. By now, you should have received a draft report of the
my
findings in the crossover pharmaco-EEG study of i-penbutoioi and placebo in 12
volunteers. 1 mailed it on January 28. i will be prepared to discuss this study during
my visit.
Attached is a statement of reimbursable expenses for this study. The
15, 1982 is exceeded, due mainly to the increased computer
time, since we carried out separate analyses for each measure and checked the
individual frequencies and different frequency bands. if there is any question, we
can discuss it during my visit.
estimate of November
My best regards.
Sincerely yours,
Max Fink, Md).
Professor of Psychiatry
�
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Correspondence to: Kleindienst, Gabriele
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mfp-05-00-030-3-077
Date
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1983
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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en-US
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/2ee2f5e0e3b28672e37d9276fb0a19e4.pdf
4b9bfd0e70678640a7290df171163c9b
PDF Text
Text
March 1, 1983
Penelope Bowers, MD.
Boehringer lngelheim, Ltd.
90 East Ridge
P.O. Box 368
Ridgefield, CT 06877
Dear Penny,
Enclosed are draft copies of the report, "Pharmaco-EEG Analysis of
clonidine (Catapres): Comparison with l-Penbutolol (Betapressin)". The report
summarizes the experiences in the two studies of Catapres which we have
completed in normal male volunteers.
Catapres exhibits central effects at single doses of 0.075 mg which peak
at two hours after dosing and are no longer measurable at four hours. The EEG
pattern are those of a sedative or hypnotic, and are not consistent with the changes
seen with typical antipsychotic, antidepressant (thymoleptic), or anxiolytic
psychoactive substances. In these trials, Catapres elicited some lowering of
systolic and diastolic blood pressures and a slowing of the heart rate.
These findings suggest that Catapres elicits direct effects in the CNS, in
doses which may be clinically relevant.
A summary of the first study was presented at the ACNP session on
organized by Dr. Richard Resnick, and was published in
Psychooharmacology Bulletin (31:16-17, 1981). Do you think a more detailed report
Catapres
should be prepared for publication based on these findings
'?
Thank you for the opportunity to carry out these trials with this
interesting and useful medicinal. My best regards.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
~
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m-
;..
Mn":
mytno-ppxmmww.“marginaqwng
�
Dublin Core
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Correspondence to: Bowers, Penelope
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mfp-05-00-030-3-075
Date
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1983
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
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en-US
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/ff27fb6a8d2a0fcab81399d1adc0ebf2.pdf
0b96375da310fb0c654c35d7559c1b22
PDF Text
Text
March 3, 1983
Ms. Gabriele Kleindienst
g
5;
:
;
‘E
E
Medizinische Abteilung
Hoechst Aktiengesellschaft
Postfach 80 03 20
6 230 Frankfurt am Main 80
West Germany
Dear Gabriele,
It was a pleasure to visit with you on February 21/22. Once again, you are
to be commended on the quality of the work that you have shown me. Keep it up ! I
hope that the discussion was useful.
We have received the reimbursement of expenses in the Betapressin study
in the amount of $7,990. Thank you. I attach a statement of additional expenses for
the latest visit.
My
best regards.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
:gn
ll
‘.I'
.
m-"I'
.-;w
v;
..
"W‘A‘I’H'
�
Dublin Core
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Title
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Correspondence to: Kleindienst, Gabriele
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mfp-05-00-030-3-074
Date
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1982
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
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en-US
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application/pdf
Publisher
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Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/080330ac1e043ab18cb1e26defd3df1e.pdf
9625d41a916074218f4455fc526e5af0
PDF Text
Text
March
ll,
1983
Aaron T. Beck, MB.
406 Wynmere Road
Wynnewood, PA 19096
Dear Aaron,
Congratulations, again,
PsychopathologicalAssociation.
on
your
award
from
the
American
As I listened to your presentation, and the sense of the sessions enquiring
into the relations between drug therapy and psychotherapy, I was mindful of the
linguistic studies of the 1950‘s. The work of Rioch, Weinstein and Kahn, and Sapir,
sought to define behavioral change in measures of language. Many authors (Jafie,
Birdwhistle, Strupp, among others) went into microlingusitics, speech pauses, typetoken-ratios and mechanical aspects of speech, but others sought to measure
definable entities like first and third person speech, denial, minimization, and
displacement. I found these ideas useful as I sought to define the behavioral
changes of patients undergoing ECT and drug therapies. In one study, Jaffe (l)
sought to define the type of psychotherapy that would be enhanced during ECT. I
reviewed that work in a presentation to the APPA in 1974 (2). I commend it, and
the interesting work of Weinstein and Kahn (3), as complements to your present
thoughts.
My regards.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
(1)
Jafie, 3. An objective study of communication in psychiatric interviews.
3, Hillside Hosp. g: 207-216, 1957.
Jafie, 3., Esecover, H., Kahn, R.L. and Fink,
psychotherapeutic transactions by altered brain
Psychothe ._l_53 46—55, 1961.
M.
Modification of
function. 5.3} g.
(2)
Fink, M. Brain function, verbal behavior, and psychotherapy. Comprehens.
Psychia . 12: 257-266, 19701.
(3)
Weinstein, E.A. and Kahn, R.L. Denial 91 Illness. C. C Thomas,
Springfield, 111., 1955.
v!
,1,
u
rm,»
um;
rmsw
“nun-warm“
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2%,
March 25, 1983
Samuel H. Rubin, MD.
Provost 6: Dean
New York Medical College
Valhalla, New York 10595
Dear Dr. Rubin,
When I accepted an appointment at SUNY at Stony Brook in 1972,
it was
with the understanding that my concurrent appointment at the New York Medical
College would terminate after two years, in 1974. l was under the impression that
my resignation was effective in the fall of 197‘}.
Your letter of February 1, 1983, reappointing me to the Adjunct
reminded me of these earlier events. While I would be pleased to continue faculty
on the
faculty of the College, my present appointment is full-time and precludes other
concurrent appointments. Please accept this letter as a note of resignation.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
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WW"ear-fr.
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March 25, 1983
Robert Arnot, M.D.
Wellesley Hills Medical Center
#22 Worcester Street
Wellesley Hills, Massachusetts 02181
Dear Dr. Arnot,
Thank you for bringing your two recent reports on the mode of action of
ECT to my attention. Your support of an electrical theory of the ECT process is
indeed interesting. However, as we and others have noted, the concept that the
electric current or the seizure 'is to interrupt the ongoing cerebral circuits so that
the brain may then start to function a ain in a more normal manner with the
disturbing pathological circuits omitted' pg 303) fails to detail how the brain (or
the seizure) knows which circuits are normal and which are disturbing. Such a
theory is reminiscent of the 'bad cell' hypothesis of insulin coma therapy espoused
by Manfred Sakel, and seems to require some additional operational details.
Such concepts help us to picture the events of the process. I note that you
Nervous System after
planned to publish two additional reports in Diseases
and Chemical
issues
the
Physical
Have
on
factors.
the one on psychological
?
Results
and
Clinical
appeared
observations,
_o__f_
My
_t_i_1_§_
regards.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
.
�
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1982
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March 25, 1983
David Behar, MD.
V.A. Medical Center
University 6: Woodland Avenues
Philadelphia, Pa. l9l04
Dear Dr. Behar,
As a start on your questions of 3/21/83, you may search the APA Task
Force Report #14 (1978) or my book (Convulsive Therapy: Theory and Practice,
Raven Press, N.Y., 1979). Both present the incidence of mortality in ECT. It is very
low, and as a consequence, it is very difficult to define 'risk factors'.
For morbidity, the question must be refined, since there are many
consequences of the ECT process, from hematoma at the injection site or postseizure excitement to complaints of amnesia. Again, the two books will help you
refine your question.
know of no studies of ECT in right (? _v_§ left) cerebral lesions since EC!”
is not ordinarily used in individuals with brain lesions. There is an extensive
I
literature of the safety and efficacy of ECT among diabetics, patients with thyroid
dysfunction, and hypertensives; and some case reports of patients successfully
treated in the absence of adrenals, with Cushing's syndrome, 939. Again, some
focus can be gleaned from these two volumes. For more recent material, you may
wish to write to Dr. Arthur Gabriel at the Mount Sinai Hospital in New York City.
He is an electrotherapist with an extensive experience with medically ill patients.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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1982
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March 31, 1983
Mr. Mark Robertson
Blackwell Scientific Publications
99 Barry Street
Carlton, Victoria
Australia 3053
Dear Mr. Robertson,
have long admired the reports by Professor Kiloh, and would welcome a
book on Physical Treatments in Psychiatry under his editorship. Having just
completed a review of the Kalinowsky and Hippius volume, it is easy to conclude
that a more authoritative and technically sophisticated volume is still needed.
1
would be pleased to assist such a venture in the way that you request.
However, would it not be more acceptable for Professor Kiloh (and Dr. SydneySmith) to accept the selection of a reviewer (or to select their own reviewer) ‘? If
you explore such a mission with the authors, and they are agreeable, I believe it
would be equally useful for your needs if the criticism is made with their
knowledge. To the extent that the criticism may be justified, it would allow the
authors to consider the suggestions in revisions.
I
in either instance, anonymous or with their consent, 1 am agreeable. It
would be helpful to know what remuneration you may have in mind.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
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1982
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—wa\
l
March 31, 1983
Dennis Charney, MD.
Department of Psychiatry
Connecticut Mental Health Center
34 Park Street
New Haven, CT 06508
Dear Dennis,
Some weeks ago, we discussed your favorable experience with mianserin
and lithium, and you told me of a report which has been submitted and accepted by
the Archives 9_f_ General Psychiatry. We are treating a depressed patient with
evidence of long standing brain damage. We have failed to alter her state with
courses of imipramine, mianserin, and she is now in a trial of lithium. Following
your suggestion, we would like to consider treatment with lithium and mianserin,
should the lithium alone fail.
Would you be able to send me a
draft of your accepted report
?
Many thanks.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
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—
«n
72,-
May 21;, 1982
Walter Sannita, Mi).
Laboratory of Neurophysiology
Ospedale San Martino
16132 Genoa, italy
Dear Walter,
First, I don't write for months, and here are two letters within a week.
write so soon to again ask a favor.
I
In today's mail, I received a letter from Prof. Franco
Angeleri of the
Ospedale Generaie Regionale in Torrette, Ancona, recommending Dr.
Marco Guidi
for a fellowship in electrophysiology in my laboratory
by
supported
a
scholarship
from the Italian government. After looking at the
and seeing that Ancona is
map
closer to Genoa than to New York, by far, i took the liberty of
writing to Dr.
Angeleri, asking that Dr. Guidi meet you.
.
Would you interview him for us ? Since
you know the situation here and
have been through a fellowship, you can explain our
principles and help Dr. Guidi
understand what he is asking.
Please be free to tell him what you recall of the laboratory. As I
wrote
last week, most of my time is now spent in
clinical activities, but we do have an
active EEG program, devoted almost exclusively to patients. We will be
doing some
pharmaco-EEG studies, but very few. You should explain the
nature of our
computer.
On the other side, I would be interested in Dr. Guidi's
facility with
English; a description of his training; a discussion of his aims, and
if you
especially
think that he will be able to achieve them here. Dr. Angeleri writes
he needs
that
an answer before June 5 to apply for a fellowship.
Thank yOu again. My best regards.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
‘
�
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mfp-05-00-030-3-063
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1980
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May 25, 1983
Prof. Franco Angeleri
Instituto Policattedra delle Malattie
del Sistema Nervoso
Ospedale Generale Regionale
60020 Torrette
Ancona, Italy
Dear Prof. Angeleri,
Thank you for your letter of May 12 regarding an appointment for Dr.
Marco Guidi as research fellow in electrophysiology. We would be pleased to
consider his application for an appointment for one year. Since Dr. Guidi has not
yet established a publication record, it would be important that he be interviewed
before a decision could be made.
A few years ago, Dr. Walter Sannita of the Ospedale San Martino in Genoa
was resident as a research fellow in this laboratory. if Dr. Guidi could visit Dr.
Sannita, it would be helpful. i enclose a copy of a letter which i have addressed to
Dr. Sannita, in the hope that he would be willing to discuss our programs, our
location, the costs of living in the U.S., and the importance of defining a project
before Dr. Guidi comes to the U.S.
For many years, my laboratory was dedicated to pharmaco-EEG studies in
normal male volunteers. These studies have, in the last year, been replaced by
studies of the. effects of drugs and convulsive therapy in patients, with the aim of
relating changes in EEG parameters to clinical outcome. The principal clinical
study is that of the mode of action of convulsive therapy. Within the Department,
there is an active sleep EEG laboratory, and it may be possible for Dr. Guidl to
work in that unit as well.
Thank you for your inquiry.
Sincerely yours,
Max Fink,
Ml).
Professor of Psychiatry
�
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1980
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May 25, 1983
Turan M. itil, M.D.
HZI Research
150
White Plains Road
Tarrytown, New York 10591
Dear Turan,
l have been puzzled by the evidence for the nobtropic class of
psychoactive substances. Using pharmaco-EEG methods, I studied a number of the
peptides for which a nobtropic status has been claimed. I was unable to elicit either
an EEG profile or evidence of behavioral effects. I have also read the literature,
and found the published data until 1981 thin and unpromising.
Lately, you have published an editorial supporting such a classification -but the editorial lacked the evidence for the claim.
I recently came across the citation list for the special issue of Drug
Development Research (2 (5), 1982) which has a number of titles which suggest
that they might contain the evidence for such a classification. 1 requested a copy.
of the journal from our library, and we have no subscription; I requested an
interlibrary loan, but as an unbound journal, it is not available. Hence this letter.
Do you have a copy of the issue ? Would you lend
Many thanks.
it to me for a few days
?
We began our first patient on Sertraline on Monday of this week. (We
actually began two, but when I checked the inclusion criteria, one patient was 70
years of age, and Dr. Gholly rejected her.) I also sent a protocol for an EEG study
for BHT 933 (azepexole) to Penny, and hope to examine it this Fall.
I trust Ellen and the children are well. We expect Jon next week, and
Rachel said that she may fly up to visit with her brother as well. I cannot get to
the NCDEU meetings this year, so will miss all the sunshine.
My
best regards.
Sincerely yours,
Max Fink, M.D.
�
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Correspondence to: Itil, Turan M.
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mfp-05-00-030-3-061
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1980
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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http://exhibits.library.stonybrook.edu/mfp/files/original/de2e5bbf85903d05b773c78f3746a4b7.pdf
81f6b922a9cf58c2e44bf3367571b02b
PDF Text
Text
December 21, 1982
Ms. Gabriele Kleindienst
Medizinische Abteilung
Hoechst Aktiengesellschait
Postiach 80 03 20
6230 Frankfurt am Main 80
West Germany
Dear Gabriele,
it was a pleasure to work with you in San Juan. Your records were
excellent, and I am delighted that you are working with such a centrally active
drug.
am planning a holiday in Israel in February. We will be leaving Tel Aviv
on Monday morning, February 21. The flight connections are difficult, but it should
be possible to be in Frankfurt that evening, and to work with you on Tuesday,
February 22. After Frankfurt, l plan to visit Peter.
I
It is also possible to visit Basie first (on Tuesday) and come to Frankfurt
on Wednesday.
Please let me know whether such a visit would be helpful, and if so, which
date(s) are the best.
,
Emily told me that the last subject in the penbutolol study is scheduled
for December 22. If that goes well, we should have the data analyses by late
January, and I could defend our findings, in person, in February. She asked me to
extend her best wishes for 1983.
mvx—x.
V~
My
best wishes for a happy, healthy, and successful 1983
l
A
'm.’
.v;
Sincerely yours,
-
.
.
”A
in.
“.1..-
1
”flora",
-""L'."‘
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7""
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fifi“’¢{‘fi'i"7‘t’fillrfl‘w€'
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Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-2-059
Date
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1980
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/2cc7a13664333e6ae81825cae590ff5b.pdf
b22e4586dcc0ecfebd2fbe4c133f4a5d
PDF Text
Text
December 21, 1982
Dr. Warren Stern
Burroughs Wellcome Co.
Triangle Park, North Carolina 27709
Dear Warren,
It was a pleasure to discuss clinical problems with you in San Juan. I
enclose a number of recent reprints of our pharmaco—EEG studies, as examples of
the power of this methodology. The study of flutroline predicted the clinical profile
more accurately than preclinical studies; and it is my expectation that the same
will be true for our study of 6-azamianserin. The pharmacodynamic study of
brotizolam is a replication of Itil's findings, indicating the reliability of the
methods. And the study of aspirin is a tour de force which we undertook as a
challenge and which has turned out to be one of our most popular and controversial
studies.
As we discussed,
I
am in charge of a l5-bed acute admission and
treatment unit and the CPD affective disorders clinic at University Hospital. 1 am
interested in assaying new entities for their psychoactive properties. While it would
be interesting to do so after their pharmaco-EEG profiles have been explicated,
this is not a necessary step. I have facilities to assess entities in patients with
severe depressive disorders, manic states, and acute sch120phrenia.
I look forward to hearing from
you. Thank you for a pleasant breakfast,
and my best wishes for a successful 1983 !
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
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Text
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mfp-05-00-030-2-058
Date
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1976
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
Subject
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/8b0c07eefd6d63479512187ab6035ab5.pdf
2d9d0e6e20d592de12695b40b3b06212
PDF Text
Text
December 30, 1982
Joseph Schildkraut, M.D.
Massachusetts Mental Health Center
74 Fenwood Road
Boston, MA 02115
Dear Joe,
Congratulations on your appointment as editor of the Journal 9!;
Psychiatric gesearch. It must be a good challenge to direct an ongoing enterprise,
and I am confident that you and Merton will work hard to maintain its reputation.
Your invitation to ‘share views about growing points in psychiatric
research, as well as areas not well covered by other journals' stimulates my reply.
Convulsive therapy remains an active treatment in psychiatry. In 1984, it will have
been used for 50 years -- a remarkable longevity when we consider that the
average half-life of medical treatments is much shorter. In the 1940's and 1950‘s,
there was the Electroshock Research Association which focussed issues about ECT,
and they published their annual proceedings in Confinia Neurologica. When that
association was prematurely digested by the Society of Biological Psychiatry in the
mid-1960's, the central focus ended. Of course, we expected the treatment to be
replaced by drugs. But that has not happened.
There is a significant gap. No journal and no society has taken the
leadership as a focus for convulsive therapy research. As a consequence, the papers
are scattered. Recently, i did a survey of the Medline citations under
'electroconvulsive therapy', and the attached data resulted.
ECT is an important treatment of depression. Indeed, I cannot see how
any research into the mode of action of antidepressants or the pathophysiology of
depressive illness can ignore the ECT process.
Considering your fling into convulsive therapy research, perhaps you and
your co—editor would want to consider a trial period in which you would establish a
section on ECT and invite review papers, conference reports, etc. My estimate of
the literature is a publication rate of 11 papers/month and increasing.
My
best wishes for your and the Journal's success.
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
�
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Correspondence to: Schildkraut, Joseph J.
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mfp-05-00-030-2-057
Date
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1980
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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http://exhibits.library.stonybrook.edu/mfp/files/original/2f944966488f9300a4b1b96e7920924f.pdf
e3df26500448a21dedfc04b831029920
PDF Text
Text
December 30, 1982
Prof. Dr. Helmut Kiinkel
Medizinische Hochschule
Karl-Wiechert-Allee 9
D—3000 Hannover-Kleefeld
West Germany
Dear Helmut,
Attached is a suggestion for an editorial for our new journal. By all
means, make corrections and additions. I tried to get the essential issues for the
journal, as I see them, in the last paragraphs. I also think it is a good idea to
separate our aims from those of clinical EEG.
"Work here is progressing well. As you may have heard, there has been
some political pressure, again in California, to stop the use of convulsive therapy. I
am busy defending this treatment, and particularly its continued research. Our
pharmaco—EEG studies continue, although a bit more slowly now that Mr. Irwin is in
Basie. I understand that there is a misunderstanding about our paper on placebo
effects in EEG. He wished to complete the report himself, and I hope that he has
done so, and sent you a copy in time.
My
best wishes for a healthy and successful 1983.
Sincerely yours,
Max Fink,
BALD.
Professor of Psychiatry
�
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Correspondence to: Kunkel, Helmut
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mfp-05-00-030-2-056
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1980
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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13d72a316b5e38a513a9c21474007c98
PDF Text
Text
StonYBrOOk
Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook.
Stony Brook, NY 11794
telephone: (516) 246-2413
v
October 18, 1982"
Paul Leber, M.D.
Division of Neuropharmacological Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20 857
Ref: IND 8,569
-
~ACTH4_10 (OI-63)
Dear Sir:
The sponsorship of IND 8,569 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
Sinc ely yours,
JM
Max Fink, M.D.
Professor of Psychiatry
�Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook.
Stony Brook, NY 11794
telephone; (516)246-2413
StonyBrook
October I 8,
19 82
Paul Leber, M.D.
Division of Neuropharmacological Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20857
Ref: IND 12,238 —- GC-46
Dear Sir:
The sponsorship of IND 12,238 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
Si
M
erelgours,
£14»!
V
Max Fink, M.D.
Professor of Psychiatry
�Department of Psychiatry and Behavioral Science
State University of New York at Stony BrookStony Brook, NY 11794
telephone: (516) 246-2413
StOHYBIOOk
October 18, l982
Paul Leber, MD.
Division of Neuropharmacological Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20857
Ref: IND 12,987 .- ACTH4_9 (ORG 2766)
Dear Sir:
The sponsorship of IND 12,987 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
fl!
Sin
relgurs,
M—
Max Fink, MD.
Professor of Psychiatry
�Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook.
Stony Brook, NY 11794
telephone: (5 l 6) 246-2413
Stan-YEW0k
October 18, 1982
Paul Leber, MD.
Division of Neuropharmacological Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20857
Ref:
1ND
13,059 -'ORG 2566
Dear Sir:
The sponsorship of IND 13,059 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
W
erelyjurs,
Max Fink, MD.
Professor of Psychiatry
�Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook.
Stony Brook, NY 11794
telephone: (516)246-2413
StonYBl-‘OOk
October 18, 1982
Paul Leber, MD.
Division of Neuropharmacological Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20 857
Ref: IND 13,060 — ORG 2313
Dear Sir:
The sponsorship of IND 13,060 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
Lia,“
//
Si
erely yours,
Max Fink, MD.
Professor of Psychiatry
�Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook
Stony Brook, NY 11794
StonyBrook
telephone=(516)246.2413
October 18, 1982
Paul Leber, M.D.
Division of Neuropharmacological Products
Food 6c Drug Administration
5600 Fishers Lane
Rockville, Maryland 20857
Ref: IND 14,915
-' ORG 3770 (6-azamianserin)
Dear Sir:
The sponsorship of IND 14,915 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
’
d“
Sinc ely yours,
/./l‘
1
,
Max Fink, M.D.
Professor of Psychiatry
�Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook
Stony Brook, NY 11794
telephone: (516)246-2413
StonYBIOOk
October 18, 1982
Paul Leber, MD.
Division of Neuropharmacological Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20 857
Ref: IND 14,963 -~ ORG 2305
Dear Sir:
The sponsorship of IND 14,963 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
Si
/
erelyJ/ours,
'
,
Max Fink, MD.
Professor of Psychiatry
�Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook.
Stony Brook, NY 11794
telephone: (516) 246-2413
StonYBIOOk
October 1 8,
19 82
Paul Leber, MD.
Division of Neuropharmacoiogical Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20857
Ref: IND 16,111
-' GK-78
Dear Sir:
The sponsorship of IND 16,111 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
-
S/i
cerely yours,
Max Fink, MD.
Professor of Psychiatry
�Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook.
Stony Brook, NY 11794
(516) 246.2413
1b
StonyBrook
October 18,
1982‘
Paul Leber, MD.
Division of Neuropharmacological Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20 857
Ref: IND 16,195 -.- ORG 2408
Dear Sir:
The sponsorship of IND 16,195 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
j
/”
SiZerely
ours ,
-
Max Fink, MD.
Professor of Psychiatry
�StonyBrook
Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook.
Stony Brook, NY 11794
telephone; (516)2462413
,
October l8,
19 82
Paul Leber, MD.
Division of Neuropharmacological Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20857
Ref: IND 16,905 -‘- ORG 6582
Dear Sir:
The sponsorship of IND 16,905 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
rely
yours,
:4
3,914.4;
//Z
Sin
Max Fink, MD.
Professor of Psychiatry
�Department of Psychiatry and BehavioralScience
State University of New York at Stony Brook.
Stony Brook, NY 11794
telephone: (516) 246-2413
StOHYBm0k
October 18, 1982
Paul Leber, MD.
Division of Neuropharmacological Products
Food 6( Drug Administration
5600 Fishers Lane
Rockville, Maryland 20857
Ref: IND 16,906
-
DGAVP
Dear Sir:
The sponsorship of IND 16,906 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this
informed of this transfer.
1ND
are being
Sinc ely yours,
M
Max Fink, MD.
Professor of Psychiatry
�Department of Psychiatry and Behavioral Science
State University of New York at Stony Brook.
Stony Brook, NY 11794
telephone: (516) 2462413
StonyBrook
October 18, 1982
Paul Leber, MD.
Division of Neuropharmacological Products
Food 6: Drug Administration
5600 Fishers Lane
Rockville, Maryland 20 857
Ref: IND 17,365 -.Mianserin
Dear Sir:
The sponsorship of 1ND 17,365 is transferred to the Pharmaceutical
Research Institute of Worthington, Ohio, effective this date.
Other investigators studying this compound under this IND are being
informed of this transfer.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence
Text
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Title
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Correspondence to: Leber, Paul
Type
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Text
Identifier
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mfp-05-00-030-2-055
Date
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1980
Creator
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
Language
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en-US
Format
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application/pdf
Publisher
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Contributor
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Correspondence
-
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ed8c055150cb32b1971ec8ff5c432a75
PDF Text
Text
July 21, 1982
Paul Leber, M.D.
Acting Director
Division of Neuropharmacological Drug Products
Food dt Drug Administration
5600 Fishers Lane
Rockville, Maryland 20 857
Ref:
1ND
12,987 (ORG 2766)
Dear Dr. Leber,
Please allow the scientists at the Pharmaceutical Research Institute of
Worthington, Ohio to cross—reference the information in our files of the ACTH4.9
fragment known as ORG 2766 (IND 12,9 87), effective immediately.
Thank you.
Sincerely yours,
Max Fink, Md).
Professor of Psychiatry
�
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1980
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1f43f549c1c33a6a7a11cbfe93c09b74
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July 15, 1982
Division of Neuropharmacologlcal Drug Products
Food a: ~{Mug Administration
5600 Fishers Lane
Rockvllle, Maryland 20857
Gentlemen:
REF: 1ND 12,987
ACTH,-9 (ORG 2766)
Enclosed is an amendment to 1ND 12,987 for a clinical trial of this ACTH
fragment analog in the treatment of patients with pituitary hormone deficiency, to
be undertaken by Dr. L. P. Kapcala of the Division of Endocrinology, Department
of Medicine, Cleveland Metropolitan General Hospltal. Copies of his protocol,
consent forms, and curriculum vitae are «closed.
Sincorely yours,
“wr
a:,:yuw'\'wvwnyqu'r:-
"'
mem
Max Fink,
Ml).
Professor of Psychiatry
�
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mfp-05-00-030-2-053
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1980
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8519111993a93691aaa3164da0cca5a9
PDF Text
Text
June 28, 1982
Mr. G. Weiss
Cardiorenal Division
Food 6: Drug Administration
5600 Fishers Lame
Rockville, Maryland 20857
Ref: IND 20,310 (kpenbutolol)
Dear Mr. Weiss,
to Hoe‘chst on 23 June regarding the dosage of
be
used
in
advised that the capsules in use are #0 mg in
our studies,
l-penbutolol
all
and
doses
dose;
test
are multiple: of this formulation.
In reference to your can
Sincerely yours,
Max Fink, Md).
Professor of Psychiatry
cc: A. Yacobow, Hoechst'
�
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mfp-05-00-030-2-052
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1980
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5b233d92d70d9a168e22eff67acc4cf7
PDF Text
Text
~,
9.»... ,n
..
.—
_..,.W_.W“ . W “m- .m-w~_
,r
V
..
.vm..-
,..
.
.
a“, ”.7. .7 Va.
mw—
'—
72'.
v
#1) 4
<-———v
-—
«w
mv—"-vmfiu’llr
er—vvwrv-r‘vv
.r—
.
March 1, 1982
w-w_.y..~_wv_..—_r
Mr. C. Prettyman
.
Ail,_“w,wm.
Division of Neuropharmacological Products
FDA
5600 Fishers Lane
Rockville, Maryland 20857
Ref:
A'WHNWW
”WV
- Mianserin
Dear Sir:
The following is in response to your inquiry of February 24, 1982.
-m<wmt=-mV—nwww"7
""1"“
1ND 17,365
in 1981, five TCA non-responding patients were inducted to courses of
mianserin. The first two patients began their treatment as in—patients at University
Hospital. Doses ranged from 20 to 160 rag/day in one patient, and 20 to 60 mg in
the second. Their clinical response was not outstanding and both went on to receive
successful courses of ECT.
Three patients received mianserin as outpatients, with doses of 20 to
nag/day. In one, the response was considered very satisfactory and the
treatment was discontinued on 2/ 15/82. In two others, the results were not
one was readmitted to a chronic hospital and the second was
outstanding
successfully treated with ECT.
120
-
Two patients have been inducted in 1982 and are now doing well under
treatment at maximum dosages of
120 mg/day.
In none of the live completed patients (and in neither of the two in
progress) have we recorded any untoward effects of the medication at these
dosages, either in the self reports, observations, or laboratory tests.
I
trust that this information is useful.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
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mfp-05-00-030-2-050
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1980
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f3bbffe66aef0cbf6a659a2555192f95
PDF Text
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February 8, 1980
Barrett Scovillo,
M.D.
HINCDS
Bethesda, Maryland
Dear
Barrett,
Thank you for the articles on barbiturate withdrawal. I raised
tho question in answer to the suggestion, made by Dr. Tyrer, that misnserin
may have epileptogonic features. His case report was flawed, however, by
the fact that the patient had had lorszepsm withdrawn two days before
the seizure.
In the recent issue of Lancet (January 19, 1980, p.151), Einsrson
four
cases of withdrawal seizures with bansodissepines in one year.
reports
Dr. Tyror’s response is also included.
It is clear
the paucity of literature and the persistence
of the question of bensodiszopine withdrawal seizures that systematic
studies in man need to be done.
from
Insidentally, I had dinner a few nights ago with Dr. John
Davis of ColuMbus, Ohio, who remarked on your work and some association
with him. I thund him most pleasant and particularly knowledgeable about
FDA and drug regulatory matters.
My
regards and
my
thanks.
Sincerely ydurs,
Fink, M.D.
Professor of Psychiatry
M3:
�
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mfp-05-00-030-1-049
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1980
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14f3de75fb50d7435b99b2cfa80ddeed
PDF Text
Text
r”
an
nwywmgp—snvr
"MW“V‘VI‘JK"
«-
~
April 6, 1980
Morris B. Bender, M.D.
Department of Neurology
Mt.
Sinai Hospital
City
New York
Dear Morris,
Belatedly, I heard of the birthday party planned for you
Orleans. I regret that I cannotaattend, and trust that Martin will
extend my best wishes in person.on the occasion, as I do now in good
spirit and with all my heart. May you have many more such happy
occasions.
in
New
We have finally moved from Great Neck, to a smaller
home in Nissequoge. Where is Nissequogue, you will ask ? In Suffolk County,
among the horse fanciers and the farms, near the University. But
is
a part of the land that is like Great Neck was soon after the second
World War, quite rural. We have yet to become acclimated (we moved at
it
the end of January) but the opening of University Hospital provided the
needed spur.o I now have an active service in addition to my laboratory and
teaching. When next you come East. let us know and I will be honored and
pleased to show you around.
Have a happy
in sending our best.
birthday and
many more.
Martha
joins
4933’:-
LEAV'F3IWV
Sincerely yours,
WW7"
'
Fxm'm'”
wwwsun
'~
~'
mz-mvwflwr
"‘t‘r’v‘ewfit-m“
new"
Fink, M.D.
Professor of Psychiatry
Max
me
�
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mfp-05-00-030-1-043
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1980
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3237127ca9d63e6af986edc24dfe106f
PDF Text
Text
April 6, 1980
Dre. R.
Jaffe,
Krieger,
H.
Sencer
Department of Neurology
8 W.
Mt.
New
Sinai Hospital
City
York
Dear Bob, Howie and Wally,
Nothing would please
me
more than to honor Morris on
his 75th birthday, and to meet with all my old comrades-in~ training.
I cannot attend, but in good spirit, and recognizing that you will
surely find something appropriate to record our debt to Morris, I
enclose the check requested.
Have a good
time.
Despite Morris' aversion to EEG, both then and now,
experience has served me well and my laboratory, which has been
dedicated to determining the effects of psychoactive drugs on the EEG
continues to be productive. Lately, we determined the normal profile
of phenytoin, aspirin, and are now working on some olfactory stimulants.
The experience at Sinai also led me to examine HOT and after 25 years,
I have put together a book which reports the clinical and theoretic
knowledge. I am most delighted with the latest theories, which hold
some promise for an improved understanding of the mode of action of this
treatment. The book, "Convuslisve Therapy~ Theory and Practice" was issued
by Raven Press in early 1979, and is already completed the first printing.
(It has also received an international award of the Anna Monika Foundation
for contribution to our understanding of endogenous depression.)
my
My
.v:
,
best regards.
Sincerely yours,
mgr
,.EV;W’hfl-'P
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-030-1-042
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1980
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6b1ad564cea89706fe2405aafee8d3fa
PDF Text
Text
.
<$I
”A.
.
September 19, 1979
"m'l-M‘WI‘WW—vv
WWW'mefl-w
Leopold Bellak, M.D.
Bronx Municipal Hospital Center
Bronx, New York
Dear Leo,
Thank you for your informative letter of September in.
I checked my file, and find that the report I submitted as a review of
the role of BCT in schizophrenia is dated July 13, 1977. Since that time,
there have been some additional publications, some noted "in press' have
been published, and what is more important, the attitude to ECT in schizo—
phrenia has crystallized-~ in part, because of the publications, and in
part because of a meeting sponsored by NIMH in February, 1978.
draft will need editing and revising. Some can be
that such an opportunity will be given
us. Otherwise, I regret to say, the publication will be outdated before
it appears in print.
done in
galley,
The
and I do hope
Let
My
me know how we
can
rectify this problem.
regards.
Sincerely yours,
Max
Fink, M.D.
Professor of Psychiatry
�Leopold Bellak, M.D.
August 17, 1977
Albert Einstein College of Medicine
Bronx,
New
York
Dear Leo,
Thank you for your comments on the report, "EST and Other
Somatic Therapies in Schizophrenia".
suggestion regarding page l,is good. Would the following
penicillin therapy successfully replaced fever therapy
for neurosyphilis, populations of misdiagnosed'schizophrenics' disappeared".
This suggestion comes from my experience at Bellevue. I came to learn about
neurosyphilis and psychosis in lean-us, just when one treatment was
replacing another. Fever therapy was used in patients where syphilis was
presumed, even if the findings were unclear (as was true for the use of
ECT). I am only trying to suggest that diagnosis issa difficult
art,
and that as new modalities are developed, we change our criteria of
diagnosis. If the sentence offends, delete it.
be
better:
The
"When
Page 11: "Whether ssuch a sanguine
an improvement.
justified" is
perhaps
therapeutic outlook is
Page 15:”These are a few questions posed by the EST
it is
Ibis sentence
time to reassess the usefulness of
removes the offending phrases.
EST
data;
in schizophrenia.‘
Page 2: The criticism of NIMH is meant to stay. I am chagrined
that the millions of dollars spent by the schizophrenia research branch
are often wasted on psychosocial approached for a syndrome whose principal characteristics are as clear as a brain disorder as are the
characteristics of brain tumors and epilepsy. The discussion of biological
research is largely biochemical and pharmacological, usually of a limited
kind. I mean to be upset by the absence of supported research in therapies
of schizophrenia. I have listened to Loren Masher and his social views
and I fins them particularly weak. Unless you insist that the paragraph
be deleted for political reasons (very sad, if you do) I would prefer
that it remain on page 2. It states a fact which I believe to be accurate
and
it
suggest
is not out of place.
My
thanks for your critique. Are there any additions you would
My
regards.
?
Sincerely yours,
Max
Fink,
M.D.
�Mme-n
w,—
.
—-
—\-.-w
V‘vr'“:
July 16, 1977
w-w-m
anwn’,"'w“f
Dr. Leopold Bellak
Bronx Municipal Hospital
Bronx, New York 10u61
Dear Leo,
Enclosed are two copies of the report, "EST and Other
Spmatic Therapies in Schizophrenia" for the next volume in the
reviews of schizophrenia.
raised not for the
ridiculously small and
in
previous ventures, byt to spell out the
quite unimportant
usual questions of reprints, author's reductions in additional
question of ’royalties'
The
amounts involved, which have been
was
volumes purchased, and complimentary copies of the volume. These
are quite customary, and it is unusual to carry out a venture
without the usual details written. For example, as a gentlemen, I
know that you will supply each author with a fuse copy of the final
volume and 100 reprints of the chapter. Yes ? And that additional
copies of the book can be obtained from the publisher at a 30%
discount ? Yes ? And that royalties will be given to the editor's
favorite charity. Yes ? (Hopefully, the royalties do not go to
the publisher who is making too much already.)
No,
In any case, I assume the above 'usual' conditions apply.
I do not need any subvention for the costs of the article. Yes,
you may have
it
for your
volume as a
gift.
I look forward to seeing the whole; I enjoyed working on
this part.
My
best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�August 3, 1978
Leapold
Ballet,
M.D.
22.Rockvood Drive
Larehnont, N. Y. 10538
Dear Leo:
Enoloeed are some notes as you requested
report in your forthcoming volume
these additions are useful.
My
to update my
I trust
on achiaophrenie.
regards.
Sincerely yours,
Fink, M.D.
Profeeeor of Psychiatry
Mn:
Mszc
Encl.
�
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mfp-05-00-030-1-041
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1980
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33bcc6e382a9c92948e278de18b5ad21
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relax-nary 25 1980
,
Dr. Samuel Bailine and
Dr. John Reu
Department of psychiatry
Long
Island Jewish-Hillside Hospital
Glen Oaks,
New
York 1100a
Deer Dre. Bailine end Ran,
to attend your presentation on February 13. The
topic is of interest to me. in large part because of my experience at
Hillside with ECT and insulin come in the 1950's. I am writing to
request a copy of your report, when it is available.
I
was unable
Thank you
for your cooperation.
,Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-030-1-037
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1980
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ed53a70736a9f436f38f60e40a1544e3
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For‘i 91.28
Adm.
State of New York
Department of Mental Hygiene
5}"
41
LONG ISLAND RESEARCH INSTITUTE
State University of New York at Stony Brook
.
fIifij/
5L
y "hf/WI}
”X?
Health Sciences Center 101'
9
IL
Stony Brook, New York 11794
STANLEY F. YOLLES. M.D.
.
DIVISION OF CLINICAL SCIENCES
MAX FINK, M.D.. DIRECTOR
M.P.H. , F.A.C.P.
INSTITUTE DIRECTOR
(516) 444-2447
(516) 444-2163
February 29, 1980
Florentine
Cambridge University Press
New York City 10022
Mr. Harry
Dear Mr.
My
Florentine,
reasons for cancelling the subscription
to Psychological
Medicine are many, some general and some quite specific. The general
reasons are the usual-- I find few articles of interest to me, and
these are generally those of a review type. Such articles are often
reproduced elsewhere so that the failure to read the article in this
journal is rarely a handicap.
for specifics, I have found the attitude of the editors to one
issue in medicine, that of convulsive therapy, quite inconsistent with
the prevailing experience. The editors seem to find the treatment
repugnant and seem to have made efforts to discredit it. In the past
As
article
on ECI' was published by Dr. Crow. I found
done, and wrote a critique addressed to the editors as a
year,
an
it
poorly
letter. It
rejected with the statement that letters are not accepted by the
journal. If true, then how can the readers redress the balance of bias
that may creep into any editorial board or correct errors that may
was
occur in any
article,
no
matter
how
well reviewed
?
I recently wrote a book on convulsive therapy, which has been
reviewed rather favorably by a number of journals, including Lancet,
New England Journal of Medicine,
and the American Journal of
Psychiatry. Yet, your reviewers chose to combine a review of this
volume, the result of more than 25 years of research, with a review of
an earlier published diatribe written by a psychotic medical
resident. In combining the two reviews, the editors did my serious
volume a distinct disservice, but more importantly, they exposed what
is clearly their bias.
�Last year, Professor Ottosson of the University of Goteborg and I
submitted a review article on a theory of the mode of action of ECT to
the journal. It was rejected as too speculative. While we accepted
this response as reasoned, the Crow article appeared subsequently. Its
quality is so inferior to our effort, that I believe bias also entered
into this decision. (The article has since been published in a fine
journal, needless to say.)
This experience follows an
earlier experience with the editor.
In 1977, I co-edited a volume on the effects of chronic hashish use.
The study was undertaken by a team of scientists working in two
countries over six years. The data were presented carefully. The
editors could not agree as to the significance of one of the findings
and it was my burden to write a concluding chapter. To indicate the
difference in opinion, I entered
a
footnote that the opinions stated
were mine alone. It was this fact that piqued the excitement of Dr.
Shepherd, and which was the highlight of the review. At an
international meeting I: met Dr. Shepherd before the review appeared
and he was gleeful that the reviewer would highlight this point. His
glee was matched by my later discomfiture at having a serious effort
distorted by the reviewer and the Editor.
These are some of the reasons
longer interests me.
why
Psychological Medicine
Thank you for your inquiry.
Sincerely yours,
Max
Fink,
M—
M.D.
Professor of Psychiatry
cc:Prof.
M.
Shepherd
no
�
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mfp-05-00-030-1-036
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1980
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51e744687b75af3629e08f27b79deaca
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March
1, 1980
Dr. Lawrence J. Lewis, M.D.
Anclote Manor Hospital
Tarpon Springs, Florida
33589
Dear Dr. Lewis,
It was kind of you to send me a copy of the evaluation summary
of the progress of Ms. Judith Parnam. She is qpito ill, and your efforts
on her behalf are interesting and described well. I hope that some progress
witl be achievod.
Thank you
for keeping
me
informod.
Sincerely yours,
Fink, H.D.
Professor of Psychiatry
Max
�
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mfp-05-00-030-1-035
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1981
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ef9fce72ff98fb209a961a187bd853e0
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December 4, 1979
Ms. Hertha Baird
University Hospital
Stony Brook, N‘Y'
Ref: Leon Hankoff, M.D.
Dear Ms. Baird,
I am pleased to write the following on behalf of the
application of Dr. Leon Hsnkoff for privileges at University
Hospital. I have known of his work in psychopyarmecology for more than
two decades, and have come to work with him in the Department at
SUNY at Stony Brook during the past two years, both in the invitation
and planning phase and in his present position as clinical director this
year.
Dr. Hankoff is a skilled researcher in psychophermacology
and in clinical sciences. He has written a fine treatise on suicide,
which has lately received excellent reviews. In the past year, he
has developed the clinical programs at University Hospital and in
this regard, he has impressed me with his patience, clarity of'
purpose, administrative and clinical skills, and reliability. He
is a skilled teacher of medical students and residents; and he has
organized a fine clinical staff which should do a credible job in
the development of the Psychiatry Service at University Hospital.
I am pleased to racemmend him for appointment to the
Psychiatry Service of University Hospital.
Sincerely yours,
Mex
Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-1-034
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1981
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74adafcec401995c0211bc32f792e914
PDF Text
Text
‘
Form ”91.28 Adm.
_
State of New York
Department of Mental Hygiene
LONG ISLAND RESEARCH INSTITUIIE
State University of New York at Stony Brook
2
"
,
'
‘
If fl)?
,5
-
._\
’
My!”
Health Sciences Center 101'
Stony Brook, New York 11794
STANLEY F. YOLLES.
DIVISION OF CLINICAL SCIENCES
MAX FINK. M.D.. DIRECTOR
M.D.. M.P.H.. F.A.C.P.
INSTITUTE DIRECTOR
(516) 444-2447
(516) 444-2163
March 20, 1980
Stanley F. Yolles, M.D.
Professor and Chairman
Department of Psychiatry
Health Sciences Center
SUNY at Stony Brook
Stony Brook, NY 11790
Dear Stan,
I have known of Leon Hankoff since the early 1960's when he was
a research associate of David Engelhardt and Norbert Freedman and
published articles in Psychopharmacology. After that research period,
I
he assumed more administrative roles. Our first working association
began last year, when he joined the Stony Brook faculty to enhance
'
the clinical services of the Department.
Since coming to Stony Brook, he has organized the clinical
services and is responsible for their continued management. In this
service, we have gained from his experience.
His principal interest is in psychiatric history and he is
studying both the phenomenon of suicide and the interrelations of
religion and mental illness. I am unable to assess this scholarship or
his teaching ability since I have had no occasion to review or observe
either. Despite the demands of the clinical service, he has continued
his studies and has published an interesting book on suicide. I have
often participated with him on committies of the Department, and recall
that he is usually with the majority.
In personality, he is friendly, out—going, and soft spoken. He is a
am encouraged to recommend the
dedicated member of the Department, and I
renewal of his term appointment.
Sincerely yours,
W
Fink, M.D.
Professor of Psychiatry
Max
MFzsl
�
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mfp-05-00-030-1-033
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1981
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d4f68394fe8170888faefd935a102657
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/
Form 91.28 Adm.
11wa
State of New York
Department of Mental Hygiene
LONG ISLAND RESEARCH INSTITUTE
State University of New York at Stony Brook
Health Sciences Center IOT
Stony Brook, New York 11794
STANLEY F. YOLLES. M.D.
.
DIVISION OF CLINICAL SCIENCES
MAX FINK. M.D.. DIRECTOR
M.P.H.. F.A.C.P.
INSTITUTE DIRECTOR
(516) 444-2447
(516) 444-2163
April 2, l980
Dr. Heinz Lehmann
Associate Director for Research
Office of Mental Health
hh Holland Avenue
Albany, NY 12229
Dear Heinz,
The tragic death of a patient undergoing ECT at Manhattan State HoSpital
month should be a stimulus to an improvement in ECT practice at MSH and
at other state hospitals. Some time ago, in October, in response to an
OMH
request for suggestions for "technology transfer", I submitted a
proposal for ECT training and monitoring. (I sent it to R. Whalen and
s. F. Yolles at LIRI. )
last
No response has been forthcoming, and of
course, such is not unusual.
However, one element of that recommendation was an invitation for ECT
therapists and nurses to attend an ECT.training session. Three are
scheduled —— in Chicago on April
at Stony Brook on April 25, and at the
APA Meeting in San Francisco in May.
ll,
I enclose copies of the Stony Brook program. Perhaps you will wish to
take credit for the application of some LIRI research to improve state
hospital services, by recommending, to the appropriate officers at OMH, that
designated users of ECT attend the session at Stony Brook.
I trust there will be an Opportunity for you to
’
regards.
visit
us soon.
.
Sincerely yours,
Max Wink, M.D.
Professor of Psychiatry
MF:sl
Encs.
My
best
�
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mfp-05-00-030-1-031
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1979
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93456237c571d75987687dccf1622471
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April 5, 1980
Corbett Thigpen, M.D.
Sebastian Way
820
Augusta, Georgia 30902
Dear Dr. Thigpen,
It
was kind
of you to send me a copy of your film, which
viewed on Monday. I have since sent the film
my associates
separately, and I trust that it will arrive safely. We found the
film interesting and a historical gem. The discussion of the history of
BCT, the experience with different modifications, the assurance of the
reporters in describing your clinical experience did make a good report
of the type of practice that has become a hallmark of modern American
psychiatry.
We were disappointed with the actual treatment, however.
I and some of
to
you
unusually busy, serving as psychiatrist, anesthetist,
seemed unfortunate that the presentation was made
as a 'modern' method of therapy. Neither the task Force report nor my own
The
and
therapist
was
physiologist. It
work would be as sanguine about such
practice in major medical centers.
would hope that such practice would be limited to those parts of the
nation where psychiatrists serve alone and where the usual support services,
so common now in major cities, were unavailable.
One
I also thank you for your letter and the reprints. I
assured that you find the use of pentelenetetrazol (Metrazol) useful in
securing a seizure in some patients, for this application is not widely
known or practiced. However, the large number of seizures you ppopose for
schizophrenic patients is a conclusion that is not supported by the data
available to us in the literature. Indeed, the conclusion is that ECT is
only occasionally useful in cases of schizophrenia, and that the use of
many treatments, spaced at three times a week is of limited usefulness.
The recommendation of the use of regressive treatment, howuumn,remains open,
following the work of Exner and Murillo who seem to find that such multiple
treatments particularly useful in therapy resistant psychotic patients. But
in their experience it is not the total number of seizures that seems to
be the controlling variable, but the frequency of the seizures and the
organic mental syndrome induced.
am
I,”
.3
-,
.1
,.
c
,uyy.
,
v
.
-1r'w[/r4._w'y:
“u
—.
i‘fiw‘ww.
-
wannvu-n-uv
WW
,p...w
film.
My
regards.
Again,
my
thanks for the opportunity to see this historic
Sincerely yours,
Max
Fink,
M.D.
�
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mfp-05-00-030-1-030
Date
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1979
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
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en-US
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/7b620a469247ce10155f70d095e07c62.pdf
ada76515877c33e23f2321ce5427efc0
PDF Text
Text
-
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sun
April 16, 1980
Barry Reisberg,
New
New
York
York
M.D.
Unietrsity College of
City
Medicine
Dear Barry,-
Please excuse the delay in answering your letter of March
24. There is no misunderstanding regarding reimbursement for BEG analyyes,
and I am well satssfied that our relationship is sound.
We
ask for reimbursement where investigators have funds
in their grants; or if they have private (industry) funds, we expect a
higher rate of reimbursement. It has been my understanding that the
studies by Gregory and Burt have not been funded and that our contribution
was in the national interest. We are pleased to have been of service, and
will continue to do so, when possible.
Call us
when you have
digested the data in hand.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-030-1-028
Date
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1979
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/7b9a5eb1c1d7111e0cfe7d595b0b5662.pdf
212e5c3d16394b4355d4416f1feb153b
PDF Text
Text
WrflaV‘m‘m
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Wvuv—u—r.
2m
“0"“,
w.
A,
m
May
5, 1980
Dr. Salvatore Manuzza
Senior Psychometrician
Child Development Clinic
Long
Island JewishéHillside Medical Center
271-11 Union Turnpike
Glen Oaks,
NY
lthO
Dear Doctor Manuzza:
The
literature
on ECT, including my own
large that I wrote an exhaustive review in
sent to the Heany Lorand library.
so
contributions,
1979.
A
became
copy was
You may also wish to see the APA Task Force report #lh published
in 1978. Between the two volumes, you should get a good grasp of ECT
issues for 1980.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
MF:sl
�
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Correspondence to: Manuzza, Salvatore
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mfp-05-00-030-1-027
Date
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1979
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/144da45f4199c94e51d3f924c1bebcc0.pdf
1ddd1081a7d7a4f43a7c83852631c53d
PDF Text
Text
May
7, 1965
Iwm
:4
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""V-
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Mr. Milan Matejcek
Sandoz A.G.
CH—h002
Basel, Switzerland
VII"?
”9‘"
mu
«raw-w»,
Dear Milan,
For your examination of the EEG effects of ngptropic drugs,
you mmyujfigrto write to Per Mindus (Department of Neurophysiology,
Karolinska Institute, Stockholm). I understand he has some reports
on piracetam which are inconclusive.
My
best.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
MFzsl
�WI
WHOM
1’
May
5, 1980
Mr. Milan Matejcek
Sandoz A.G.
CH-QOOZ
Basel. Switzerland
Dear Milan,
have never developed a special program of analysis for
'nootropic' drugs. In our work, we have taken compounds of different
structure, and sought to assess their EEG profiles against the known
active compounds for different mental conditions. In the absence of
any effective compounds for the alleviation of the memory changes seen
in the elderly, we have not been able to define a nootropic profile.
I have enclosed copies of our most recent reports, including the summary
We
wv
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New:
-
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111'
-
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prepared for the
1978 EEG
congress.
two occasions, we analyzed tapes prepared by others in their
study of supposed vasodilators. These reports were negative, but I enclose
copies of the data summary for your information. While these are unpublished, you may quote them if you wish as personal communications.
On
that the evidence presented so far,
for a definite profile for a nootropic class of drugs is unconvincing. I
have yet to see a definite report of either EEG or clinical activity for
piracetam, and the data for other such agenst is equally weak. In a
similar vein, we have been uanble to define activity for the fragments
of ACTH and it is unlikely that the slight behavioral effects will have
As
any
when
an opinion, I would say
clinical utility.
it is
Good luck
completed.
My
in your review. I look forward to reading a copy
best regards.
W
a
.
Sincerely yours,
Max
Fink,
M.D.
�
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mfp-05-00-030-1-026
Date
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1979
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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en-US
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/c2c2dfb7bb346adb52598b6971e8d9b9.pdf
04f1a81c2137da712f07c8735cbab196
PDF Text
Text
May
[
8, 1980
Dr. Mary Jasti, M.D.
thOhO Queens Boulevard
Forest Hills, New York
Dear Dr.
Jesti,
I regret to tell you that we lack facilities to support the
studies of lithium that you propose on behalf of yuur sister. Such
studies could be undzrtaken by the many laboratories dedicated to
lithium research.
Thank you
for your interest.
,
E
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-030-1-024
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1979
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/ded6393ec11db912f42db4ffab2fd56b.pdf
ea8ff6eb4d1cb4e82bd3f23caaf117ba
PDF Text
Text
.m
FWVlmVr-z
November 17, 1981
Dr. Richard A. Hrachovy, MD.
Department of Neurology
Epilepsy Research Center
Baylor College of Medicine
6516 Bertner Avenue
Houston, Texas 77030
Dear Dr. Hrachovy,
l was sorry to hear of the problem in patient recruitment. The amendment
is acceptable end has been filed.
to the
enclosed for your records.
1ND
A
copy of the letter of submission is
if you are coming to the ARNMD meetings in New York in December,
perhaps we could meet ? i plan to attend the afternoon session on Friday and will
look for you at the registration desk at the end of the session.
Good luck.
Sincerely yours,
raw—r
Max Fink, M.D.
Professor of Psychiatry
�
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mfp-05-00-030-1-020
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1979
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http://exhibits.library.stonybrook.edu/mfp/files/original/083b1eba2dccc162cb3eeeb96cdf3da0.pdf
4949af8c87a5d5a15086d17736eb572c
PDF Text
Text
wruvlr‘
‘
-..,
m
mwmmmww-v
November 18, 1981
Solomon Sobel, MD.
Division of Metabolism
and Endocrine Drug Products, HFD~130
FDA
5600 Fishers Lane
Rockville, Maryland 20857
Dear Dr. Sobel,
This letter is in response to your letter of October 30, regarding 1ND
16,906, and our study of DGAVP. l have written to the manufacturers in Holland
and requested their advice as to whether they have made
any further in assaying
the 34% of material not identifies in the present DGAVP formulation.
Their reply
will be sent as soon as received.
To date, in our normal volunteers, we have observed no untoward effects
of the use of this formulation in acute trials.
Sincerely yours,
Max Fink, MD.
Professor of Psychiatry
�
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mfp-05-00-030-1-019
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1979
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http://exhibits.library.stonybrook.edu/mfp/files/original/fc6914a13ae34955cf6b62288fea897d.pdf
71284e82ac0d488732388eae40700914
PDF Text
Text
n"..-
wwwmmgv
“W
Wrwv-Vt
~r.-
umm‘qu-Wl-wv
wuv-wvw
3*
WW
\W
October 1, 1979
Prof. Dr.
H. Helmchen
Nussbaumallee
1000 Berlin
36
19
Dear Helmchen,
for the reprints of your studies of the behavioral
changes in epilepsy. I found the work quite good and complementary to
our own interest in the effects of seizures in ECT. Over the years,
I have often wondered why more epileptologists did not take advantage of
the natural experiments which psychiatrists provide in the BCT process, in
aleowing a study of the interrelations between degree of brain change,
number and frequency of seizures, and psychopathology. When I did my
principal studies of psychopathology, in the late 1950’s, not as much was
known about the assessment of behavior and our work was quite coarse.Were
we to do the same studies today, our methods would be more detailed and
would parallel your efforts more closely.
Thank you
I also enclose a reprint of our recent study of the EEG
effects of phenytoin. It shows clearly that there is an intimate relation
between plasma level of phenytoin and BEG response. I think the failure
of many physicians to get behavioral effects in patients with neurosis may
be due to the low levels they used.
Again,
my
thanks for your help.
My
best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-8-305
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1979
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/1fdb5e009877e1de6cbd14bc2c55c9b1.pdf
e62742f96ebb6d89f768c477afd00b6a
PDF Text
Text
yr.
,
‘rww-v fl...“ 1. «w, ”w . .2...‘_-..,..
,
~
v...”
,nmuvwm...wnmww.-m
,e-
,P\,.—
WWW...
Sctober-l2, 1979
a...
Theodore R. Waugh, M.D.
Department of orthopedic Surgery
York University Medical Center
New
New
York
City
Dear Dr. Waugh,
RE:
Jan Volavka,
M.D.
I am pleased to write this letter of recommendation in
support of the appointment of Jan Volavka, M.D. as Professor of Psychiatry.
I have known of his work since 1966, and I was instrumental in providing
a place for him in the United States when the Russians overran Czechoslovakia
in 1957. He joined my staff at the New York Medical College and worked with
me until I left in 1972. Thereafter he moved to Missouri, where he worked
in the laboratories-at the Missouri Institute of Psychiatry which I had
established in 1962~ 1966.‘
He
Volavka is a personable and unusually talented researcher.
is a trained psychiatrist and physiologist, and has skills in computer
vDr.
sciences, electroencephalography and statistics. While with me, he made
interesting contributions to our studies of the effects of ECT on brain
function, the.EBG effects of cannabis, and the relations between EEG
measures and behavior. He has since made important contributions in the
study of opioids and endorphins, and he is best known for his studies of
the relations between genetic markers (XXY and XYY) and EEG variables. The
latter studies have been in progress in Denmark for mere than a decade.
He is an independent investigator, with innovative ideas
and unusual skills and talents. His writings are clear and definitive. He
has managed patients and treatment units with ease, and he is well liked
by his co-workers.
I commend him, without reservation, for appointment as
Professor. (Indeed, I did the same in recommending him for a position
at this University a few years ago, when he decided to go to St. Louis.)
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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Correspondence to: Waugh, Theodore W.
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mfp-05-00-029-8-303
Date
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1979
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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Source
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1503e128e6ef7ce06ceb6281ecf1a30b
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Text
October 15, 1979
Peter J. Knott, Ph.D.
Marshall University
Huntington, West Virginia
Dear Dr. Knott,
principal recent publication devoted to studies of
mianserin is the special issue of the British Journal of Clinical
Pharmacology, Supplement 1, volume 5, 1978, titled "Proceedings of
a Symposium on Mianserin- October 1977". This should be in your library.
The
As
best as I can
tell,
the spondors of mianserin are
clinical trials necessary to establish an NDA in this
country. I have no knowledge as to when it is likely that it will
doing the
be introduced.
Thank you
for your interest.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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év
October 15, 1979
Jose Carranza, M.D.
University of Mississippi Medical Center
Jackson, Mississippi 39216
Dear
New
Jose,
I was sorry to hear that the arrangements
York did not work out. I enclose a copy of the
requested.
for the move to
report which you
During the past year, I have curtailed my travel since
I have been away from my laboratory more than it could bear. If you
wish to arrange a lecture in Jackson, I would make the time in the
late spring of 1980 or the early fall.
Thank you
for thinking of
me.
My
regards.
Sincerely yours,
Pink, M.D.
Professor of Psychiatry
Max
�
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my”
u
vi,—
s,
mmwwrw-qryq
a-m
October 15 , 1979
Jerome Levine, M.D.
Chief, Psychopharmacology Research Branch
NIMH
--
-
Rockville, Maryland 20857
Dear
Jerry,
-Thank.you for the copy of "Coordinating Clinical Trials
in Psychopharmacology", which I was able to read this past week-end.
to the earlier guidelines which have been
It is an excellent addition
and
provides an enViable standard for
issued by the Institute,
it some
of the sponsors of our studies of
notified
have
future trials. I
and
am sure that they will find it
I
of
the
volume,
the publication
useful.
I also want to thank you for the assistance you have given
of Organon. He has accepted the responsibility for
of
guidelines for the clinical trials sponsored by that
developing a set
he
has
and
written
a number of recommendations which clearly
company,
NCDEU
these will be adopted by his masters
believe
I
standards.
meet
well
as world-wide (although they have some
0.8.
the
as
for studies in
in countries where the AMP system
the
with
coordinating
trials
problems
Dr. Hank van Riezen
is standard).
:
Our own
-
-.
.
laboratories continue to assess new drugs in
we have identified three new putative psychoactive
phase I trials, and
3770, is
drugs in the past 18 months which have much promise. One, Org EEG
and
active than mianserin and tields a similar
behavioral profile, promising to be even safer than mianserin in lack
frustrated by
of cardiotoxicity and anticholinergic effects. We have been 1980
studies
the
ACTH
and
that
optimistic
are
fragments,
the studies of
My book on
DGAVP)
he
rewarding.
and
(DTVE
will
tore
of other peptides
BCT (Cbnvulsive Therapy: Theory and Practice) has been well received and
the first reviews were most kind. It also receiVed.0he of the 1979 Anna
Monika Foundation awards, so I am rather pleased.
clearly
much more
Again; thank you for sending the Volume.
My
best regards.
Sincerely‘yours,
'
"‘I-vw-rc
Max
Fink,_M.D.
Professor of Psychiatry
�
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mfp-05-00-029-8-300
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1979
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d303f7247c39a5abc72e39d71c661960
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m... V"...we:
November
2, 1979
Peter T. Loosen, M.D.
Dorothea Dix Hospital
Raleigh, NC 27611
Dear
Peter.
Thank you for the two articles, on the oral treatment
of depressed patients with 80 mg TRH and the review of peptide effects.
I had seen the Karlberg et al article, but in light of our discussion,
I should be disappointed and assume that the likelihood that TRH over
three weeks would be significantly antidepressant. Yet, the many observations
including the three patients who responded in this series, suggests that
we may be close, as close as the early workers were with l-dopa in parkin-
son patients.
For the meanwhile, I have decided not to replicate the study;
but rather to try with two of the newer peptides, DGAVP and des-Tyr-gammaendorphin, to assess their central (EEG) effects.
My associate, Yiannis Papakostas has been carrying out
stimulation tests and dexamethadone—cortisol tests in every one
of our depressed patients, referred for drug therapy or BCT. So far, in
the first 15 patients, he has found more consistent DM-cortisol abnormalities which resolve with treatment, than TRH-TSH but the latter do occur
in about 1/3 the cases, and he is confirming the observations of TSH blunted
response in some depressed. He is using our schizophrenic patients as
controls, and we are particularly interested in the ECT group.
TRH-TSH
It
was kind
of
you
to think of
me, and my
thanks.
Sincerely yours,
Pink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-8-296
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1979
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cffa51d34daeb806ae302986ce50bc13
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E’ ,7 wn
,
-~-
—.
-
“er—w.“
v
www.mm u.‘
~
.
u
77x-
_,_, awe—mm
, Wu-“'~"AV‘—W1m’
av ‘I'run‘rrr-w—Mc'
'Vw-v-mr'w.u-r“-u-.mmw “cw-«ww’ww‘
v.
,
mummy» Mm..." ”WWW". "HM", _-,,
a—nwmw-eu-r-vmrv-“v—hw.’»-~»
.
__
.
WM”
November 3, 1979
E
g
g
E
Alan
Frazer,
Ph.D.
Depression Research Unit
Hospital
Philadepphia,
VA
PA.
Dear Alan,
Thank you
;
E
'
’
E
n
{
E
I
i
r
for sending
of beta-adrenergic receptors as a
me
your report on the subsensitivity
test for antidepressant drug activity.
report is quite interesting and well done, but like other such
efforts,which seek a single test to define 'antidepressant' activity,
seems to fail in not being inclusive. The problems with such efforts
are many, but the principal one highlighted by this report is the
expectation that a single system is involved in treatments as diverse
as BCT, TCAD, MAOI, stimulants, etc., just because these various systems
seem to be useful in relieving a single symptom. Is it not likely that
the various 'depression' syndromes reflect different mechanills, just
like fever and headache may reflect different underlying pathophysiologies
The
course, that mianserin did not fit within the model leads
to the speculation that perhaps mianserin is not an antidepressant But,
as you are well aware, it is also possible that the single system studied
is not general enough to be related to the syndrome of depression. I
am confident that mianserin is an antidepressant, not because of its
clinical evidence, but because its EEG profile in man is so like amitryptiline,
that it will have the same or similar effects on brain function, and in
depressed patients, should have the same behavioral effects as seen fiith
amitryptiline. To the extent that amitryptiline is "antidepressant', so
is mianserin.
Of
I
I
b
E
?
liberty of sending your report to my
studies, Dr. J. J. de Ridder of Gas, Holland,
with a note that he may write to you if he wishes additional information.
I would be grateful if you would oblige his inquiries, if any.
I
am taking the
my mianserin
collaborator in
My
regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-8-295
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1979
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http://exhibits.library.stonybrook.edu/mfp/files/original/0f0542033598988f757d372cbe9ffe6a.pdf
d65a2269cfaf7a4741779df955fd1993
PDF Text
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November 5, 1979
Mark S. Beaubien, M.D.
Assistant Chief, International Cooperation
and Geographic Studies Branch
Fogarty International Center
Dept. of Health, Education & Welfare
Rational Institutes of Health
Bethesda, Maryland 20205
Dear Dr. Beaubien,
Dr. Drigoltav V. Ereegovse visited our facilities during
week of October 29. He toured our Health Sciences Center,
observed EEG recording sessions in volunteers and discussed our
EEG methodology; visited our V.A. clinical study unit and observed
modern methods of ECT and discussed principles and theories of ECT.
we fOund him to be a delightful visitor and guest, and we hope that
the
we
contributed to his
Thank you
"ETA".
for referring
'
him
to us.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
MF:bo
�£1239£0537
9’9
R
,
$0M];
/
@950 75% 30’
§:P
A
{90
(7‘94:
I
0'
f/if?
q
5951
71/
.
July 17.
MBrk
1979
8. Beaubien, M.D.
Assistant Chief, International Cooperation
and Geographic Studies Branch
Fogarty International Center
Dept. of Health, Eaucation & Welfare
National Institutes of Health
Bethesda, Marylanfi 20205
,Dear Dr. Beaubien,
We would be pleased to hava Dr. Ercegovac visit our laboratorics
during the week of Octdber 29, 197§. It would be helpful for
Dr. Ercegovac to let me know what aspect of our studies interest him.
the
I suggest he call
visit.
me
at
516~hhh~2hh7
'
in September to discuss
Sincerely yours,
Fink, 14.1»;
Professor of Psychiatry
Max
MF:bc
3,?
�
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mfp-05-00-029-8-294
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1979
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-
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08bd5f56dfe8bf9c06a0f4c7d3ccafd5
PDF Text
Text
November 5, 1979
Richard
D.
Weiner, M.D., Ph.D.
V.A. Hospital
Durham, North
Carolina 27705
Dear Rich,
After a hectic few months, I have finally had the time to
read the many reports and papers that have been on my desk since my
holidays. Among these, was the report "ECT and Seizure Threshold" as
presented at the Society of Biological Psychiatry. The paper is quite
good, reflecting many more cases than I thought had been studied.
There is little that I can argue with in the data, but there
questions inherent in the attitudes expressed. As I understand
the study. it is an assessment of two aspects of induction, electrode
placement and electric currents, with a number of criteria—- duration
of seizure (or seizure threshold). degree of amnesia, total energy,
are
some
clinical efficacy. Others have carefully documented that electrode
placement alters clinical outcome little, but does reduce the degree of
amnesia and alters the type of disorganization in neuropsychological
tests. But the evidence for different effects for brief stimuli is
still sparse. In Weaver's recent studies, he found that his LEBS delivered
less joules to the 'head', but he could not demonstrate a difference either
in clinical assessments or in degree or type of amnesia. In similar
and
.
fashion, the present report also fails to define such differences.
Yet, in a number of places, the implication is raised that
brief stimulus treatment (MBCTA) is 'better'. For example, on page 1, you
combine two thoughts in one sentence: "Two modifications of BCT technique;
lateralized brain stimulation via unilateral electrode placement and the
use of brief pulse stimuli have made it possible to diminish the
severity of side-effects . . ." Again, on page 8: "No difference in
suprathreshold seizure duration on the basis of stimulus waveform
was
found, suggesting that not only are the seizures with brief pulse stimuli
produced by lower amount of electrical energy, but also that they are
equivalent in terms of potency. . ." Now, the word 'potency' is not defined;
I know you mean potency to deliver a seizure, but then, could it not mean
potency in clinical terms ? This is compounded by the phrase (page 9, top)
".
.
and thereby possibly
less therapeutically potent.9
I agree that a detailed test of the MECTA machine (or other
brief stimulus) is needed, but the assessment should indicate the number
of patients treated, the number of missed inductions, the number of seizure
�Richard D. Weiner, M.D., Ph.D.
......
November 5, 1979
.........
page
2
seconds, changes in depression ratings, tests of neuropsychological
functions, etc. Much of this has already been done for unilateral
and bilateral electrode placements, and the evidence is quite compelling.
Similar assessments need be done for brief stimuli, and until these are
done cleanly, the equivalent efficacy of brief stimuli and safety in side—
effects will remain open questions.
Perhaps, such an assessment can be the basis of a collaborative
and I would urge you to work with Dick Abrams to fermulate a useful
protocol. I would hope that the issues (induction factors, assessment
factors) will be defined carefully.
effort,
Again,
My
thanks for sharing these progress reports with
for the delay in reading.
my
me, and my apologies
regards.
Sincerely yours,
-
.
-
u
A.
Fink, M.D.
Professor of Psychiatry
Max
~m-aw>r-w~.W;w--—m—.——W<Wmnwp
that a bill regulating the consent procedures for
psychosurgery and convulsive therapy is being prepared for the Assnmbly
of the State of New York. I have read a preliminary draft, and it is clearly
modelled upon the recent Califbrnia statutes. It is probable that the APA
will be asked for its help by a committee in New York headed by Dr. Hurray
P.S.
W>w‘a\w"'
.w
wan—,v.
w,.._..——wy
v
V
w.»
.v
You should know
Glusman of the New York State Psychiatric
fitter from him or from the APA.
Institute;
and you may be hearing
�
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mfp-05-00-029-8-293
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1979
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6c351587bb117bd009d25e0e5ae8da5f
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November 5, 1979
Dr. P. Tyrer
Department of Psychiatry
University of Southampton
Southampton, 509
hPE
Deer Drs. Tyrer, Steinberg and Watson,
The report of the possible epileptOgenic effect of misnserin
(Lancet, October 13, 1979) is for from compelling. You note that the
patient. with a long history of recurrent depressive illness, received
nitrezepam, lorszepsm, and misuserin on admission for "a further episode
or depression precipitated by the death of her husband." Hitresepsm was
stepped soon thereafter; and for six weeks she received lorszepem and
misneerin. Three days before a seizure, she stopped her lorszepsm.
You conclude that this episode suggests that misnserin may have
epileptogenic features, and caution physicians in prescribing misnserin
in patients with a history of seizures.
Was the possibility of the seisure as secondary to the withdrawal
of benzodissepines ruled out as an explanation for the seizure? If so,
how?
If
she presumably had no history of seizures, how can one conclude
that misnoerin should not be given to patients with a history of seizures?
�Dr. P. Tyrer
‘
2.
Nov. 5, 1979
'
have examined the EEG effects of mienserin in volunteer subjects
in patients.“ we have described systematic EEG effects, but these
are unlike those usually seen with compounds inducing seizures. While
such studies do not preclude seizure induction, the likelihood is
remote, and we suggest the alternate explanation, of benzodiezepine
We
and
withdrawal, as more likely.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Mex
“Fink, M., Irwin, Pi, Gastpar, M. and do Bidder, H.: EEG, Blood Level, and
Behavioral effects of the Antidepressant Mienserin (Org GB 9h).
Psychoghermacologggigg; 2h9—25h, 1977.
Irwin, P. and Fink, M. EEG Study of Misuserin (GB 9h) in Depressed Patients.
Brit. J. Clin. Phamacol. 2: (Suppl.): h38-h93, 1978.
MF:bc
�
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mfp-05-00-029-8-292
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d9ad64bb56fd52237d4ee40a735383dc
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November
Paul G. Meyer,
7,
1979
M.D.
Texas Tech University School of Medicine
79u30
Lubbock, Texas
Dear Dr. Meyer,
Thank you for the invitation to apply for the position of
chairman of the Department of Psychiatry at the Texas Tech University
Health Sciences Center. I am not unhappy at my present location and
am not available for such an eppointment; I am honored that you thought
of
me.
'
Two of my students and co-workers, Dre. Michael Allen
Taylor and Richard Abrams are now at the Chicago Medical School. I
believe that they are restive and that either one would be a fine
academic leader.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-8-291
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1979
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‘55“:
._
November 7, 1979
Hon. May w. Newburger
N.Y.S. Assembly
Albany,
New
York
Dear Ms. Newburger,
It was kind of you to remark on my award for my 25 years
of research into the mode of action if convulsive therapy. I hesitate to
presume on this kindness, but in the same mail, copies of legislation
being considered by the Assembly Ways 8 Means Committee came to my attention
which led to this flatter. The proposed legislation ire amendments to the
mental hygiene law establishing standards for consent and disclosure for
the administration of psychosurgery and convulsive therapy (Amendments to
Sections 33.03).
The amendments for ECT are badly intentione-, seeking to
deprive the mentally ill of the State of this specifically effective and
safe form of treatment. The regulations propose to make more difficult
the task of administering treatments to voluntary hespdtdiized patients
and to render almost impossible to administer the treatment to involuntary
patients. The law is patterned after legislation in California, which has
led to the present traffic of patients from California going to Oregon
and New Mexico for treatment. This, of course, provides that only the
wealthy and self—insured are able to obtain this treatment. The legislation
is based on the erroneous belief that convulsive therapy is unsafe and
ineffective; the contrary being true, since all evidence finds that this
therapy is the most effective and the safest for endogenous depression.
In our 1976 survey, 5% of admissions to University centers in New York
City received this treatment (and only 1% of admissions in V.A. and
State facilities; clearly evidence of some reasoned use at University
settings.)
The amendment
for psychosurgery is also flawed. This
treatment is still an experimental one, and is at present only available
in Descarch setting where cases are reviewed by Institutional Review Boards.
The legislation adds additional onerous requirements for consent, making
the research even more difficult. At this time, the reports from Great
Britain suggest that this therapy has a usefulness with patients with severe
obsessive compulsive and phobic states. Thése data need verification. The
legislation will serve to reduce the studies, not encourage them.
�Hon. May
Newburger.........
November
7, 1979
..........
page
2
I hope that you will have an opportununity to review
these proposed laws and do what you can to prevent their adoption. If
there is any question regarding theta objections, I will be pleased to
meet with you in Great Neck to discuss it further.
Thank you
for your consideration.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
39
Arleigh
Great Neck,
Road
516 #66 sunu
New
York
�
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mfp-05-00-029-8-289
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1979
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64be78e179cb4891b20b9e29b892fe5c
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November 1n, 1979
E. Kielkopf, Chief
Contract Review Unit
Ms. Mary
NIDA
5600
Fishers Lane
Rockvfille,
ND
Dear Ms. Kielkopf,
I am willing to participate in the NIDA contract review
I
enclose
system.
a short resume which highlights my professional
experience, oaitting the publication list which is a bit long. My
publications in drug abuse encompass the long term effects of cannabis,
narcotic antagonists, EEG effects of opioide and antagonists, methadone
and levomethadyl therapy, among others.
Thank you
for the invitation.
Sincerely,yours,
‘flé:§¢”fifiifilfir
Pink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-8-286
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1979
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11df0ad7e126ea056f19f37658592cef
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November 1n, 1979
Sigurd Aokermen, M.D.
Montefiore Hospital
Bronx, New York 10MB?
Dear Sig,
Enclosed are the two
reprints concerning our
studies of lactate in anxiety. The letter was a way to indicate that
we-had replicated the findings of Pitts and McClure. We did not go
further as the proposals, sent to NIMH, were not accepted. (Since
then, the reviewers have undertaken very similar studies.)
sample.
The EEG
report
summarizes our few records
in the
.
I hope these are of interest.
discussing your work.
My
It
was a
pleasure
regards.
Sincerely yours,
"fife-w
Fink, M.D.
Professor of Psychiatry
Mex
first
�
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mfp-05-00-029-8-285
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1979
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65fafa09f33f224d65ac92f327de17c4
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November 20, 1979
Dr. Henry H. Work, H.D.
Deputy Medical Director
APA
1700 Eighteenth
washington, D.C.
St.
N.W.
Dear Henry,
EEG
Thank you
Society guidelines
for the opportunity to
in
EEG,
1976.
comment on
the American
Clinical electroencephalography is a discipline which is
more than 50 years old. Mich information has been extracted from EEG
recordings by clinical and research neurologists and psychiatrists; and
yet, there remains a divergence of opinion in different centers retarding
the applications of this methodology. The disagreements are not related to
technical equipment, since these are quite sophisticated and reasonably
foolproof. Much of the discordance seems to relate to the differences
in montages used, controls for recording, location of electrodes, and
measurements made. The awareness of the divergence in skills of recordists
and eiectroencephalographers led.the American EEG Society to establish a
Board for qualification, training courses for recordists and readeree and
these guidelines.
The guidelines are an amalgam of many opinions, and there
are many fine points with which one could argue. In breadth of detail,
in sensitivity to the need for adequate training and the realities of
what the marketplace would hear, and as a service to our profession, the
guidelines seem excellent and servicable. I believe they should be
adopted by the APA,~and recommended to our membership. There are many
institutions, particularly those proprietary hospitals without academic
affiliations, and the State and V.A. hospital systems which may find the
recommendations onerous, even expensive, but in fairness to their patients
and with the optimism that the best medical care should be provided all
Americans, these guidelines are a small step in upgrading an important
service.
I
recommend endorsement.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-8-282
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1979
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85c74f3e9c73d9b2c1661f8e9a4a1061
PDF Text
Text
November 10,
Dr. Barend
ter
luA Regent
Street
Editor,
TINS
Hear
-
ter
\
\
'
Balbridge, England.
Dear Dr.
me
L
‘
Hear,
Since submitting an article on.the neuroendocrine aspects
of convulsive therapy in early August, the BCT scene in Great Britain
has been noticed by the editorial writers of Lancet, British Medical
Journal. and Psychological Medicine, making our article in TINS more
timely.
note in
What
file is
is the publication dtttus.of the report
dated
an additional paragraph.
my
23 August 1979 and acknowledges
? The
Sincerely yours,
Pink, M.D.
Professor of Psychiatry
Max
last
receipt of
�
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mfp-05-00-029-8-281
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1979
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c8457ec344ab1bb8f185274eab5f2688
PDF Text
Text
‘
m»
December 4, 1979
Mb.
Hertha Baird
University Hospital
Stony Brook, flew York
Dear Ms. Baird,
Re: Dr. Sherman
Kieffer
I hate known Dr. Kdeffer since 1972, as a fellow Professor in
the Department of Psychiatry and Behavioral Science at SUNY at
Stony Brook. In that time, I have worked closely with him in
Departmental matters and have come to know his skill as administrator,
clinician, and teacher.
Dr. Koiffier has an extensive experience In the U.S.
Public Health Service, and his knowledge has been most useful in the
development of programs in drug therapy. He is a kind and gentle
man, with infinite patience, tolerance, and reliability. Hie
expertise is in the study and management of drug abusers and in
this regard, he is one of our nation's fieaders.
I
am pleased to recommend him for appointment to the
of University Hospital.
service
Psychiatry
:v.
:,
Py-w-vw‘u
Sincerely yours,
«fly-32:"
wwmmW—rMa—vn-w
"W
'
=-=
ELY!
m
rmL-m
‘rvggw;
a”
wawvsvmvrw-wbw
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-8-279
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1979
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Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/6fc1db21879a352f15410a95c6319267.pdf
a5a16d6c080eab9ee171e2fca9136c11
PDF Text
Text
->«
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-
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h
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19 December 1979
-
John T. Brauchi, M D
Professor and Chairman
Department of Psychiatry
Louisiana State University Medica1 Center
P. 0. Box 33932
Shreveport, Louisiana 71130
Re: Dr. D1iver T. Nikd1ovSki
‘
Dear Dr. Brauchi:
Dr. 01iver Niko1ovski was a member of the staff at the New York Medica1\
Co11ege during my tenure in 1966 to 1972.1nitia11y, he served as a
research psychiatrist in psychopharmaco1ogic studies; 1ater. he was the
c1inician in the
Day
Hospita1.
.
“
=
During the time he worked with me. I found him a 10ya1 and dedicated .\.
worker. He is Sincere, honest, and responsibie. He was we11 1iked by
the Staff and the patients and he was enthusiastic to carry out the studies
we designed.
Dr. Niko1ovski is an exce11ent member of a c1inica1 team. and he has the
ski11s to carry out c1inica1 functions in the management of the treatment
of the menta11y'i11. I recommend him for a c1inica1 position. without,
hesitation. 'With regard to his capacity—as a residency trdhing director.
I am unabie to give'you any definite opinion. since_he did not function
in this ro1e during his tenure with us; nor was I ab1e to observe his
teaching sessions, since these were 1arge1y part of the c1inica1 teaching
sessions.
I
,
trust this information is useful.
Sbncere1y yours,
MF:BK
Fink, M.D.
Professor of Psychiatry
Max
'
.
_.
\
�
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mfp-05-00-029-8-275
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1979
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
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918af09b310b8cdcfb0bf8e99ce4b55f
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A
lav/W
,9
111
r.
fl
.
4-.
we.-.
m.
7‘
v..._,..__,.,.,..y,w..._
19 December 1979
Hubert A. Carbone, M.D.
Chief of C1inica1 Affairs
Northviiie Regiona1 Psychiatric Hospitai
_
41001 Seven Miie Road
Northvi11e, Michigan 48167
mu”
1-
Re:
n
01iver T. Niko1ovski, M.D., D.P.M.
'Dear Dr. Carbone:
mmru—w—uow'uw
01iver Nik010vski was a member of the staff at the New York Medicai
Co11ege during my tenure in 1966 to 1972.1nitia11y, he served as a
research psychiatrist in psychopharmacoIogic studies; Iater, he was
’Dr.
the c1inician in the
Day
Hospitai
During the time he worked with me. I found him a ona1 and dedicated
worker. He is sincere. honest. and responsib1e. He was we11 1iked by
the staff and the patients and he was enthusiastic to carry out the
studies we designed.
DrI'Niko1ovski is an exceIIent member of a c1inica1 team, and he has
the sk1115 to carry out ciinicaI functions in the management of the
,treatment of the menta11y i119 I recommend him for a c1inica1 position,
_without hesitation. VWith regard to his capacity as a residency training
director. I am unabie to give you any definite opinien, since he did not
function in this ro1e dUring his tenure with us; nor was I ab1e to
observe his teaching sessions. since these were 1arge1y part of the
c11nica1 teaching sessions.
I
,
trust this information is usefui.
,
Sincerer yours,
'
In“,
Ame
yarn—m“...
'
“always“
g‘v'
-~
.
2.»
WWW—"we,
0.,..,}...V
Wmm—
MFzBK
'
.
.g
.
Max Fink, M. D.
-Professor of Psythiatry
'
�
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mfp-05-00-029-8-274
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1979
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http://exhibits.library.stonybrook.edu/mfp/files/original/4de71a7437deef8161ba90c16c13f187.pdf
5611f37f0ca0dff25f85e6570fdea4d8
PDF Text
Text
~
'
July 5.
1979
Simha Tyk
1651 h7 St.
Brooklyn, N.Y. 1120b
Dear Mt. Tyk,
referred to in your letter of June 18, 1979 is
not yet in trial in the U.S. we are required to undertake extensive
clinical trials in hospitalized patients to verify the European
claimn before the U.S. Government will allow the compound in
'The compound
clinical use
—
if it is
this material will
It is not likely that
in the U.S. before 1982.
safe and effective.
be available
Regretfullx,
Me: Pink, M.D.
‘
MF:bo
Professor 5: Psychiatry
�
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mfp-05-00-029-7-272
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1979
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http://exhibits.library.stonybrook.edu/mfp/files/original/a5f4d25e8a07a244ad0fd4387348a12e.pdf
f4240166e54ab657ee9d34c5962ff705
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Text
July 10.
1979
Dr. C. L. Faingold
P.O. Box 3926
Springfield, IL 62708
Dear Dr. Faingold,
for sending me a copy of your report on the
I found it interesting and
of
antihistamines.
action
therapeutic
when
me
studied
the effects of antireminded
I
that
helpful. It
induced
slow
in the EEG by induced
waves
the
on
cholinergic drugs
seizures (ECT), I found that a series of central anticholinergics
(atropine, diethazine, benactyzine, diethaidlsuld reduce slow wave
activity dramatically. At the time, Dias-Guerrero, Feinstein and
Thank you
Gottleib (Electroenceph. clin. Neurophysiol. §5299-306, 1956)
reported that diphenhydramine also reduced EEG slow wave activity
after ECT. We believed then that this effect was related to central
anticholinergic effects of diphenhydramine-- perhaps that was a
reasonable guess.
have not continued our studies of antihistaminics,
back
but may get
to it if terfenadine gets to the marketplace.
We
My
thanks again.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-7-271
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1979
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1700ea176b4caf8911f70d05a27225f4
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July 20, 1979
John Mann, M.D.
Department of Psychiatry
New York University College of Medicine
New
York City 10016
Dear Dr. Mann,
I
returning the EEG samples sent me. As we discussed,
these samples seem to represent the four montages of a single session
in each of four subjects. It is not possible to determine 'drug effects'
from such a sample, and when you reach the investigators again, you
may indicate that the need is for serial records, taken with bee same
montage, preferably at the same time of day and with some control for
the state of vigilance of the subject. (It does us little good to
get records with subjects asleep on one occasion, awake the next; one
hour after dosing on one occasion, and six hours on anther; etc.).
I am sorry about the crossing of the two protocols for the
study of depression, but look forward to your combining the best of
both. Let
am
me know
My
what tou decide.
regards.
Sincerely yours,
v
.,
.
v
.
..‘.v..:..
w,‘.,_,-,-.~.,..v
”A
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-7-268
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1979
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http://exhibits.library.stonybrook.edu/mfp/files/original/79d1b4b00c5d60f51bc3693952085d5c.pdf
535d842cbe0e4aa450ef8a78f0cb0c1b
PDF Text
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Joly 20,
1979
Dr. Joe Tacos
Department of Psychiatry
Tufts University
Boston, Massachusetts
Dear Joe,
was kind of you to write and to send your latest
have Just cited your work id a summary of the
Dahlem Conference on pattern recognition, in which we were
interested in different methods to describe the changes induced
in behavior by various stresses or agents.
It
.reprint. I
Enclosed are some examples of our recent EEG studies.
For the most part, these reflect the two themes of our EEG
work, the characterization of new drug profiles and the
determination of the pharmsoodynsmio activity of psychoactive
drugs. The DPH paper is particularly illuminating, indicating that
even when some authors fail to find a profile for a psychoactive
grog, determination Ind cognizance of the pharmacokinetics will
win
it
out.
I aid complete 3 book on
has been well received.
My
regards,
and
I
EDT
this year,
earlier
*
do look forgard
to
and
San Juan.
sincerely yours,
Fink, M.D.
Pfofeasor of Psychiatry
Mix
�
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mfp-05-00-029-7-267
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1979
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/37183291d1a937714fde41612b9a3fc6.pdf
116b2052eefac476ff66969c76e58c66
PDF Text
Text
1".'~——-..,»m
..
‘
var.-
r-‘(uV—V'V mar-Hr
v.
wr-Irw“'
Hm
-
mw-
.r-I“
wu-
——u-——mv—_l—,‘
w—m—m—rw—
"WW—w
.npmww—quur
;
;
E
July 28,
Dr. Barend ter Hear
Trends in Neurosciences
Elsevier/ North Holland
1979
Cambridge CB2 lDB, U.K.
Dear Dr.
ter
Hear,
Enclosed is a draft copy of the revised report on the
in convulsive therapy, re—titled, A Neuroendbcrine Theory
of’aonvuleive Therapy. I am grateful for the clarifications resulting
from the questions raised by your reviewers, and I believe the paper
clearly separates what is established by research and experience and
mechanisms
what
is speculation
on my
part.
the criticism of the lack of citations and yet,
I have noted that all
citations to the experience with convulsive therapy are to my volume;
to
To answer
meet the normal standards of the Journal,
all the statements regarding the
neuroendocrine hypothesis are
supported by references to the work of others. Almost all the
citations to articles to the end of 1978 are also included in my
volume, but the ones in 1979 are not. It seems that this solution
to the questions may be manageable.
I look forward to your review..
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
~v.‘lw-uwunm.vw—.'—Fv—
�
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mfp-05-00-029-7-265
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1979
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34f1693f315fe966ec3f3a023c115d81
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Text
‘
IV_'
{4.
i
v?!“
”mum‘s.”
-‘l."!£
..
Must I.
Philip
R.A.M&y, M.D.
U.C.L.A.
~:
1979
Lon Angeles,
California
9002h
wreamatrm-“w
Dear
Phil,
.‘h'
'1‘
I was pleased ta submit a letter on your behalf for
pramotion to Professor in Residence V. I did so at the request of
Milt Greenblatt. I hope you get the promotion.
my
.vys—n
~
best regards.
Sincerely yours,
Fink, M.D.
Pgofessor of Psychiatry
Mg;
‘
.
rmi‘m‘i‘iw"’
"'
x
mar,
-—.v
�
Dublin Core
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Correspondence to: May, Philip R.A.
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mfp-05-00-029-7-263
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1979
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Correspondence
-
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Milton Grocnhlatt, M.D.
Department of Psychiatry & Behavioral Sciences
U. California, Los Angeles
Los Angeles, California 9002h
Deni-
Milt ,
It
an
;. following on behalf of the
preposed. advancement of "
Professor in Residence V.
My acquaintance 175th Dr. ?..
q'
his
publications and in
our activities in the American Collcge of Neuropsychopharmacology.
'
.
.
Dr. May's outstanding contribution has been a study of the
treatment of the severe mentally ill by drugs, milieu and ECT. This
work clearly demonstrated the efficacy and safety of drug therapy in
those patients. Surprisingly. the efficacy of ECT was also demonstrated
and in this regard, the reports are among the more important in the
literature. For this contribution, he was awarded the Paul Book Award
of the American Psychopathologicnl Association.
His breadth of intsreat is seen in his writings in such
topics as statistics, prediction of treatncnt response, paychologicll
teats, rehabilitation, mantel health care delivery and nursing. He
has also written on natural history topics, particularly in the habits
of woodpeckers.
In addition to his teaching of residents in training and
modical students, Dr. Mhy is an authority on the treatment of
schizophrenia and has preparcd cassette tapes for post graduate education
on
this topic.
He
has served as President of the Amcrican College of
serving that socioty wall for a number of years.
Rouropnychophnrmacology,
Dr. May in well known in this nation and overseas for his
contributions, erudition, and divcrsc inteiesta. It is a pleasure to
recommend him highly for promotion to Professor in Residence V.
Sincerely yours,
Fink, M.D.
Pfofccsor of Psychiatry
Max
�
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awn, u...“
m: “grew”.—
<
1:
August 16, 1979
Richard Friedenberg, M.D.
New York Radical College
Valhalla,
New
York 10595
RE:
‘
Rhea Dornbush, Ph.D.
Dear Dr. Friedenberg
I have known Dr. Dornbush since she Joined me at the College
in 1967, to participate in an HIMH supported study of the effects of
ECT on memory function and behavior. In this study, she developed
sensitive
memory
tests
which were applicable to studies in elderly and
depressed patients, and her contributions were invaluable.
we then worked on the problem of the long-term egfects'of
cannabis use, both in studies at the College and in a special population
in Greece. In this study, she became the principal organizer of the studies,
made many trips to Athens,,developed the data analyses, and formulated
" Hashish:
many of the publications which resulted, including the volume,
Raven
1977.
in
Press
Studies of Long-Term Use", which was published by
flew
York
the
She also organized a conference on chronic cannabis use at
Academy of Sciences and published the Iolume of the proceedings.
left New York to work as research director for the Masters~
Johnson institute in St. Louis. Apparently, that was an unfortunate choice
because it was seemingly impossible to provide a scientific basis for the
heuristic clinical skills and dogma expressed by these chiarismatic teachers.
NINE
She
She
returned to
New
supported study of
York a few years ago, and has since developed an
memory
effects of peptides, in collaboration with
other investigators working
on
this interesting problem.
me
and
is a skilled, dedicated, experienced, and talented researcher.
She has exhibited skills in teaching, organisation of experiments, writing,
and in her professional talents, in the design of experiments and their
Rhea
She is well liked by her co-workers and has the
experience and knowledge which are required for a position as Professor
statistical analysis.
of Psychiatry (Psychology). I
recommend
her highly.
Sincerely yours,
Me: Pink, M.D.
Professor of Psychiatry
�
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mfp-05-00-029-7-261
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1979
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http://exhibits.library.stonybrook.edu/mfp/files/original/aedd1c160ca39d1e016d1076b2e79a3f.pdf
da33a21cc99745d88bcfe40f07c27602
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F752“
WM'Wv—ww—Frmiwfl"
__
August 16, 1979
Ming T. Tsuang, M.D.
University of Iowa
Iowa City, Iowa
Dear Ming,
Thank you for letting me read the report on death and suicide
in schizoaffective patients. It is an important contribution to our
growing awareness that ECT may have some long-term etfects on behavior
and death rates. Mbst impressive, is the careful follow-up and the
contribution to our assessment of schisopffective disorders. I
interpret the finding as another clue to the inclusion of schizoaffective
disorders under the rubric of depressive disorders, and not schizophrenia.
I look fbrward to the succeeding reports cited in the article.
Good luck in your year in England. I hope that you will have
opportunity to consult with those scientidts assessing the effects
of ECT in Britain. Apparently, the Royal College has received a grant
to assess the long-term effects of ECT and your skills would surely
some
be
helpful.
My
best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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mfp-05-00-029-7-260
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1979
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5f3ded2326e00d788868f02c2f9c34eb
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Deanery 28, 1979
Drs.
J.
Knowle
Gill
Lambourn and D.
Hospital
Fareham, Hants , England
Gill,
Dear Drs. Inmbourn and
I have read your interesting report comparing simulated and
in the latest issue of the British Journal of Psychiatry. As
you know, the findings seem contrary to the studies which we and
Ulett gg_al. published in the 1950's. A principal difference in the
studies is the use of different electrode placements to induce seizures.
It is possible that this difference may explain the findings.
real
ECT
The procedure
notes that "Those in the active group received
a
brief pulse stimulus of approximately
a
bilateral seizure
to produce
a
How
the seizures
10
Joules.
bilateral modified convulsion on
was
the seizure monitored
. . . This was noted
every occasion."
? How
was
this assurance of
documented ? What was the average duration of
so induced ? And, was there a measure of total seiture
time for each patient
?
Another way to these data may be in the interseizure
measurements. Were any measures of brain function, as EEG or psychological
tests,
done before and
after
6
treatments, or after the final series
I would be grateful for any additional data
to help explain the unusual findings of this study.
Thank you
you may provide
for your help.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
?
�
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mfp-05-00-029-7-259
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1979
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63ef38735aa469957fb5c961b418ca83
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r—w—
.
.‘mw—wWWWWlW “we"...‘
...v
1mww‘ we .
,
.
1mm.'~v
w-—‘-—mm——qu
.. _is .Vr
w-v—
wriv
-u-v:
C
l
August 17 . 1979
Drs.J.
Lambourn
Harrison Hospital
Dorset, England
Dear Dr. Lambourn,
me a
ECT.
letter is in the nature of a belated thank you for sending
detailed version of your ECT study comparing full ECT with simulated
It is difficult to fault your study, for some of the controls which
This
seemed necessary (and omitted from the BJP article) were included in
your study, notably measurement of seizure duration and evidence of
bilaterality of seizures. Your findings remain inexplicable in the face
of our experience, and perhaps the best explanation may lie in the
question raised by Jan-Otto Ottosson. He notes that not every seizure
is full in the brain, and indeed, in our studies of the EEG effects of
ECT and flurothyl seizures, we did find patients in whom the EEG changes
were astonishingly small compared to others; yet we believed we had
achieved full seizures and had measured their duration. While this
remains a conjecture at this Junction.
may be an explanation,
it
In our study of subconvulsive—convulsive ECT, we used a minimum
of 12 seizures and our data fell compellingly on the side of sonvulsive
therapy being more effective than subconvulsive. The best description is
found in my book which has Just been published by Raven Press.
Your data are puzzling and one would hope that in addition
to your further studies of differenttcurrents on the ECT process, that
the mesurement of the seizure itself may be done to assess whether the
differences in outcome may be related to ancettbeal difference—~ shorter
EEG seizure time, less spiking activity, gtg_as suggested by Ottosson.
regret that I find in the aftermath of your study is
Dr.
Kalinowsky to harangue the psychiatric readership
the opportunity given
with his antipathy to unilateral ECT. I cannot believe that this factor
alone explained the difference in outcome, but perhaps it was a factor.
(Our studies and those of Ulett were with bilateral electrodes.)
The only
These thoughts are inconclusive, as you can tell. I think
your study well done and I congratulate you and Dr. Gill on carrying
out. I can only hope that you will persevere to explain the difference
between your findings and some of the others in the literature.
it
Good
luck in your work.
Sincerely yours,
Max
Fim‘,
MOD.
-
raw
.
w n-rw
"
v
�
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mfp-05-00-029-7-258
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1979
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ec72b17156175228660cba42efa2e022
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h
<:l$>
July 16,
1979
Dr. Candace B. Pert
Clinical Center,
Bethesda,
MD
Dear Dr.
Pert,
I
NIMH
20205
embarrassed that other committments kept me from
my associates were kind enough to keep notes and
me. I have sent your expensesvouchers to the
administrative assistant, Mr. Vacnon, and you will be reimbtrsed
am
your lecture, but
shared these with
in
due course.
Our studies of des—Tyr-ypendorphin are on 'Hold', pending
re-assessment of the pharmacologic data. The material prepared by the
chemists in Holland meets all the chemical standards for purity, but
has not shown the pharmacologic activity claimed in the initial samples.
Our studies will wait on the re-assessment and possibly another batch
production. Perhaps these experiences are a caution to the workers
in this field, that chemical purity may not be a guarantee of
pharmacologic equivalence.
him
Have you thought of writing to Dr. David de Wied and asking
for samples of his original material to test in your test systems ?
I trust we will meet on another occasion, and have the
opportunity to discuss this exciting work.
My
regards.
Sincerely yours,
Anal“
th Fink, M.D.
‘WW‘WMLVWJ
‘v'a
*LWJV.
A
4
{MM
know if my associate showed you the book on ECT that
I published earlier this year. I took a flyer in that work to
suggest that the mode of action of convulsive therapy was bound up in
its liberation and stimulation of brain peptides with behavioral
effects. I emphasized the experiences with TRH and ACTH more than
with the endorphins, however.
P.S..I don't
�«we. .m-n—
wiwvwv-m—v-
W~wwmw~v~v~w
..._,.
v”
a,..,.-.rm.._....-....._.-.w—~-w
.._
May
.1
~_
1*.
,— “H...”
1979
Candice Pert, Ph.D.
NIH
Bethesda, Maryland
Dear Dr.
Pert,
It was kind of you to accept our invitation, and I
look forward to your visit on June 25. Separately, you will receive
a formal invitation and details regarding the arrangements for your
lecture. I am writing to give you some background to our present
needs and our wishes for your contribution to our program.
The Long Island Research Institute is the youngest and
smallest of the three research institutes in mental health in New
York, having been established three years ago. Many members of the
staff are involved in research efforts which had their origins in the
enthusiasms of the past two decades. The Division Directors have
recognized the nature of these ifforts, and seek to broaden the ex—
perience of the staff. One of the issues which has been prominent this
year, is that of the developments in psychoneuroendocrinology. In this
regard, we have invited Peter Stokes, Arthur Prange, Bernard Carroll to
lecture to our staff.
Both Dr. Harvey Karten and I have been interested in
studies of the effects of peptides on behavior and we are interested
in your experiences and the development of the concepts underlying
the activity of endorphinsfi:opiate receptoss with their possible
effects on behavior. No work of this kind is in progress at this
time. The closest is our EEG studies of ACTH fragments and the studies
of des-Tyr—f-endorphin which will begin in the next few weeks.
we would be delighted to have you describe your present
theories. It would be particularly helpful if you could help
us see this work in the context of the developing science.
work and
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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1979
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b9e1bc1b73aa742dc2073156bf223015
PDF Text
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mum-~-<m-..,.
1.3:":
Ww
July 16, 1979
Dr. Harry G. Pars
SISA
Incorporated
Cambridge, Mass. 02138
Dear Harry,
It
to chat with
you again
in Baltimore. I
interesting, particularly the reports of the
antidepressant effects of endorphin.
I enclose two reprints- one, our assessment of DH-52h
suggesting that its EEG profile was more similar to that of
cannabis derivatives and therefore of psychopharmacologic interest;
and a recent summary of the EEG profile methods, indicating that
the methodology seems to have a place in phase-1 evaluation of
new putative psychotherapeutic moieties.
mg.-
A—w
was good
found the sessions very
EEG
Let
enhancer'
place).
-
My
me know
it
if you
come
across a viable 'alpha
clinic (and the market-
should be useful in the
regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
é /7« 3f“ 2J3";
�
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1979
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-
http://exhibits.library.stonybrook.edu/mfp/files/original/8a26029ef4b979d79207eb9b36fa32f5.pdf
507fd73b4f7ce18d05137ecefe1ef820
PDF Text
Text
77......
.
,._v-w.-,~.
.
a
.,
.
-.-.rr 'W-v<
-
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.—
»
-Vrl'-v—v—vv.‘I—v'~-—y--w--...» «.7...
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September 5, 1979
Tom G.
Bolwig, M.D.
University Hospital
Copenhagen, Denmark
Dear Tom,
St. Moritz,
Your
where
letter
I had
was waiting
some pleasant
for me when I returned from
meetings, with among others,
Dr. Rafaelson. I will be pleased to have you visit anytime between
October 25 and 31, as I shall be at the University during that period.
The University is about an hour from my home, and about 1.6 hours tram
midtown New York. If you will let me know what other arrangements you
want to make during your stay in the city, I can suggest arrangements
that would be most convenient for your stay.
The study of the the MECTA and other currents is needed.
One such study is underway by Dr. Richard Weiner (V.A. Hospital,
Durham, North Carolina 27705) and a few others have been talked about,
but I do not know that they are actually in progress. Dr. Weiner has
you may
some data already, and
your visit to the U.S. allows
want
to
meet with him.
it,
if
few weeks ago, I received a careful letter from Dr.
that I had mix-read the European usage of ECT in
delirium. He clarified the issue for me, much as you have done. I think
any report in the U.S. Journals which indicates that delirium may be
A
Heshe, indicating
ECT is needed. I regret that the Amer. J. Psychiat.
editors rejected the article. If you would like to have it published
in the U.S., perhaps you should try Dr. Fritz Freyhan (2015 R.Street, N.W.,
Washington, D.C. 20009) who is editor of Comprehensive Psychiatry. If
you decide to submit it to him, indicate that the usage is different in
the two countries, that my book needs amplification, and that I suggested
referral to him. Good luck
an indication for
1
Would you be willing to discuss your work with some of
our residents during your visit 1
Give my regards
pleasant dinner.
My
regards.
to Dr. Rafeelson and thank
him
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
for a
most
7.. e 7,,
v... w _
new—3...".
�
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mfp-05-00-029-7-251
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1979
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c2e4684e8e1d98ad6455b5f09b152161
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July 2.
TO:
Stanley F. Yolles,
FROM:
Max
SUBJECT:
Fink,
1979
M.D.
M.D.
Proposal by N.S. Lehrman, M.D.: "Psychotherapy with a
Recidivist Chronic Schizophrenic Population..."
This
is
l.
description of the characteristics of the
an ambitious treatment program dedicated
to a
psychotherapeutic interaction in chronic, relapsing schizophrenic
patients. The study is based on an uncontrolled, impressionistic
study in which "More than 30 chronic, repeatedly admitted...
patients have been receiving treatment in this fashion... since
November 1978, with apparently excellent results so far...".
Since neither the case description, the intervention, nor the
outcome criteria are described, it is not possible to assess the
success of this "intervention". If the therapy is so rapidly
(November 1978 — May 1979) effective, it must be powerful indeed,
and we are entitled to a better description. Specific questions
that should he answered to allow a reasoned review are the
“
following:
selected.
A
°
30
patients.
'
.
2. Number, frequency, duration of interventions .
3. were medications maintained at pro-therapy leVels, or
changed? If changed, how often, by shat criteria and with what
outcomes?
.
,
u
,
b. What are range of changes,
which are the basis
their incidence,
for' 'excellent results".
duration,
and
f?
-\
*
a
*R
.
}
are the characteristics of the panposed psycho—
therapeutic interventions, particularly, how are these distinguished
5.
from
What
established therapies ordinarily available in the
institutions.
:
OMB
]IX
.
I
'.:\A\.“
\
�~
If; i d
\‘r
89F. Y°1.QB,
Until such
for support.
MF2bc
2.
MOD.
data. are provided,
'
«1111?
2! 1979
the study cannot be recomended
�may
To:
8. F. Yolles, M.D.
FROM:
Mex
SUBJECT:
Fink,
9. 1979
M.D.
Replacement for Mr. Robert Bienatook
I
would like to recommend the appointment of two young
women, Miss Stephanie Orson and Miss Jane Engele to replace
Mr. Robert Bienetock. Each of these appointees is recommended
on a half time basis, effective June 2, 1979. Attached are
copies of
their
Thank you
Mszc
Att.
Curriculum Vitae.
for your help.
�October 13, 1978
Stanley F. Yolles,
HSC
SUNY
at Stony
M.D.
Brook
Dear Stan,
I am writing this letter on behalf of Dr. Kenneth Tardiff,
in support of his application for promotion to Associate Professor.
I have known him since he Joined our faculty in 1975 and while I have
had little opportunity to assess his clinical or research
ability, I
have worked with him th the Psychobiology System, and
is
that
it
I came to appreciate his skill as a teacher and his interest there
in the
students. In the year that we worked together, I found him enthusiastic,
dependable, and appreciative of the problems of the students. He worked
well with
us on the committee and
facilitated
my
teaching.
It is from his record that I have to assess his research
clinical skills. It is clear that he has the academic training and
interest, and his publication list and independence of research efforts
and
during the past year indicate that he has the basis for a research
contributions of high quality and innovative creativity.
fellow
of the Department, I have found him
and quiet. In the committee, he has
been prepared and presented his work welll I believe he carried outalways
this assignnent to our satisfaction; I surely have no awareness of any
deficiency in the training program or in the appreciation of the students.
warm,
As a
member
interested, restrained,
From a number of points of vies, I believe he has achieved
the record which will Justify an enthusiastic recommendation for promotion
to Associate Professor of Psychiatry.
.Sincerely yours,
_
Fink, M.D.
Professor of Psychiatry
Max
�April 11,
8. F. Yolles,
Pink
1973
Institute Director
T0:
From:
N.
Subject:
Appointment of Dr.
Y.
Papakestos
will complete his third year of residency
has applied to me to join the LIRI research
programs and I would be pleased to have him work with us, if we
could generate the support necessary.
Dr. Papakostos
training in June.
He
In 1977, Dr. Asnis was a full time employee of the
Division of Clinical Science. When he went to the V.A., he went
as half-time LIRI and half—time VA. When he resigned in January,
I recohmended that John Lee, then on 'soft money', be appointed to
his half-line at
LIRI.
Dr. Lee will be appointed to 5/8 VA in order to take
advantage of the rules that only employees at the VA who are 5/8
or more can apply for VA grants. That will occur in May/June and
will leave 1/8 of a line free at LIRI.
Whatever happened to the
other half of Asnis' line
?
it permanently 'lost' ? Is it possible to use that half a
line plus the 1/8 from John Lee to create a 5/8 LIRI line, possibly
for Dr. Papakostoa ?
Is
Two issues are at hand: the abailability of the 5/8
line and the possibility of appointing Dr. Papakostos to that line
if available.
�){1
£11in
March 23. 1978
MEMORANDUM
TO:
Dr. S. F. Yolles
mom Dr.
Max
Fink
I am writing to recommend the appointment of Dr. Leon D. Hankoff to
the Department of Psychiatry. at the rank appropriate to his experience.
I have known Leon for two decades, primarily as an administrative physician
who headed local hospital departments of
psychiatry. Three
ago, he
consulted me with regard to the development of a study of theyears
behavioral
and EEG effects of benedialysis. A grant application was
prepared but was
not approved. In working through the details of the protocol, I came to
respect ht! clinical experience and judgement, and his enthusiasm for
research. He is skilled in the administration of a psychiatric clinical
service, has an interest in clinical research and has supported research
studies of members of his staff. He would be a valuable
addition to our
clinical service.
He has served as a teacher at the various schools with which
he has
been affiliated—- Downstate Medical Center and New York Medical College,
and has taught social work students. His skills as a teacher would be
most
useful.
It is a pleasure to recommend his appointment to a senior position in
the faculty of the Department of Psychiatry and Behavioral Science.
bc
�February 20, 1978
TO:
S.F. Yolles,
Fink
M.D.
From:
Max
Subject:
Leb~0ffice Building
are completely out of the Lab—Office building as
of today; except for the air conditioning unit in Room 8323.
As soon as this is disconnected, I vill arrange to have it stored
in Great Neck.
We
to have the
Brookdale.
is a better source of payment, I will arrange
paid for from the Psychopharmacology funds at
Unless there
move
�
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Correspondence to: Yolles, Stanley F.
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mfp-05-00-029-7-250
Date
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1979
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5725b69986cdfe793fcebabf5039b81b
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C3¢.:
‘/:/ici;€§xéd’
September 6. 1979
Dr. Jack weinberg
Chairman, A.P.A. Nominating Committee
c/o American Psychiatric Association
1700 Eighteenth Street, N.W.
Washington, D.c. 20009
Dear Dr. Weinberg:
I
would
like to endorse the nomination of Stanley F. Yolles,
as candidate for the position of Treasurer of the
Association.
American
M.D.
Psychiatric
both nationally and internationally for
his contributions to the prevention or and treatment for the mentally
National Institute of Mental Health, he
ill. As Director of thewhich
made the Clinical Center one of the
provided the leadership
and
training sites; and in his eight years at
world's finest research
Stony Brook, he has stimulated the development of a leading Department,
research institute, and training center. In all these years, he has
been an active supporter of the A.P.A.
Dr. Yolles is currently Professor and Chairman of the Department
or Medicine of the
of Psychiatry and Behavioral Science in the School
He
held this post
has
Brook.
New
York
at Stony
State University of
and developed its
school
medical
new
when
he opened a
since April 1971
Director of
been
the
has
he
1975
also
Since
programs in psychiatry.
N.Y. State
or
the
arm
research
the Long Island Research Institute, a
Brook
campus.
Stony
on
the
located
Office of Mental Health, which is
in
he
a
completed
career
Chair
Brook,
at Stony
Prior to assuming the
with
internship
an
Service
beginning
the United States Public Health
in his appoint—
at one of its hospitals on Staten Island andHe culminating
from
the Service
l96h.
retired
ment as Director of the H.I.M.H. in
Admiral)
1971.
in
(Rear
General
with the rank of Assistant Surgeon
the P.H.S.
in
Bureau
status
achieved
N.I.M.H.
Under his stewardship, the
500
million
over
was
slightly
with resources reflected in a budget that
Stanley Yolles
dollars
when he
is
left.
known
�Dr. Jack weinbcrg
I have
known
“
'
2.
Stan Yolles since 1962,
Sept. 6, 1979
when
I
first
worked with him
is an outstanding administrator and a dedicated and
He has been a menber of the A.P.A. since 1953 and
worker.
tireless
active in A.P.A. budgetary affairs since 1970. This background in
at N.I.M.H.
He
administration and finance qualifies him uniquely among the A.P.A.
for the position of Treasurer. A copy of his Curriculum
Vitae is attached.
membership
I an pleased to endorse his nomination and commend him to the
Nominating Committee.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
MF:bc
Encl.
�
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1979
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75377629cc54150c4541efc55131b0f7
PDF Text
Text
September 9, 1979
Dr. R.
M. Hodges
3720 Hampton Road
Pasadena, Cal. 91107
Dear Dr. Hodges,
of the
Enclosed are a number of reprints of our recent studies
effects of drugs.
We have two applications of these methods—and classify putative psychoactive agents, and to describe
the phramacddynamics of the compounds.
EEG
to identify
In our work, we use an IBM 1800 which was programmed mar
machine language more than 12 years ago. I fear that these programs are
of little merit to any investigator wishing to program modern machines.
The logic of power spectral density is published in engineering volumes,
particulary by Blackman and Tukey (Measurement of Power Spectra, Dover,
N.Y., 1958) and that of period analysis by Burch et al (Ann. N. Y.
Acad. Sci. 115: 827—893, 1964). The most recent descriptions of programs
(HZI Research,
for small computers were those written by Dr. T.
150 White Plains Road, Tarrytown, N.Y.) and Dr. D. M. Shapiro (2 Hemlock
Drive, Kings Point, NY 11023). Dr. Shapiro is a computer consultant who
programmed my machine and a number of successors, and you may wish to
write to him for the availability of programs and their translation for
your instrument and purposes.He would be particularly helpful in advising
you as to the feasibility of doing BEG spectral work on small instruments
of the kind that you describe.
Itil
Thank you
for your kind
Good luck
in your work.
comments on my book on ECT.
It
has
received a favorable review in Lancet and has been awarded the 1979 prize
by the Anna Monika Foundation of Germany for its contribution to the
study and understanding of endogenous depression.
Sincerely yours,
Max
Fink,
M.D.
PRofessor of Psychiatry
�
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mfp-05-00-029-7-247
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1977
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Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
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41fd04b3a71c2eae424ecb53bd80ceff
PDF Text
Text
WWW—"ww
-s—FVV‘m—u—rw.
w
"w...““wwraw—w—q—Tv—
W"
ram—-
WWW
{is
September 12, 1979
;
l
Mrs. E. L. DeRnbeis
5
McLean Hospital
115 Mill Street
g
l
Belmont, Massachusetts
'
i
,
E
:
é
i
F
i
i
02178
Dear Mrs. DeRubeis,
I am pleased to recommend the election of Dr, Philip
Skolnick for membership as a-Scientific Associate of the ACNP. Dr.
Skolnick is a senior investigator at the NAIMDD in Bethesda and
despite his years, has already made an excellent reputation as a
pharmacologist. He has published more than #0 papers and his work
has been accepted as pioneering.
Dr. Skolnick has developed a methodology
to demonstrate
that brain tissues have henzodiazepine receptors. This striking finding
(Did God really anticipate that Hoffmann La Roche would develop and
sell benzodiazepines ?) has been replicated by others and is the subject
of a 0.8. patent held by Dr. Skolnick.
i
E
5
f
f
I have
known
of his work for the past two years, and have
heard him present his findings with
clarity
and enthusiasm. He
E
I
i
Sincerely yours,
I
i
I
|
E
i
I
i
Q
i
I
t
I
is
an
experienced investigator and his contributions to the ACNP could be
important. I would welcome him as a member of the College.
Max
Fink,
Fellow,
M.D.
ACNP
Professor of Psychiatry
�
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Correspondence to: DeRubeis, Eleanor L.
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mfp-05-00-029-7-242
Date
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1978
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caa69d73bcedfd949754488e0791b69b
PDF Text
Text
iW'
/
"WT—w.“
Am‘mm‘
‘7
September 12, 1979
“mm—WWW-
Corbett H. Thigpen, M.D.
820 St. Sebastian Way
Augusta, Georgia
30902
Dear Dr. Thigpen,
Would it be possible to boorow a
of your film
for a review at my University ? I would becopy
interested
in
the opportunity to see your way of treatment and will accept
responsibility for careful handling here.
on ECT
Good luck
in your presentation at the
APA.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
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Correspondence
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence to: Thigpen, Corbett H.
Type
The nature or genre of the resource
Text
Identifier
An unambiguous reference to the resource within a given context
mfp-05-00-029-7-239
Date
A point or period of time associated with an event in the lifecycle of the resource
1979
Creator
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<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
Subject
The topic of the resource
Correspondence -- Correspondence
Relation
A related resource
The Max Fink Collection
Description
An account of the resource
Rights
Information about rights held in and over the resource
<a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a>
Source
A related resource from which the described resource is derived
Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
Language
A language of the resource
en-US
Format
The file format, physical medium, or dimensions of the resource
application/pdf
Publisher
An entity responsible for making the resource available
Contributor
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Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/76690204694bf2ac1b9e1a557d91fc64.pdf
ac221d84063ee8c340548bbd75b6c554
PDF Text
Text
September 12, 1979
Prof. Dr. J. Angst
Psychiatric Clinic
Zurich, Switzerland
Dear
Jules,
Thank you for your kind letter, congratulating me on
election as President of the Association of Academic Psychiatry. I
regret to say that I have not been so honored, and I imagine you are
thinking of Paul Fink of Philadelphia.
my
and
my
I have been honored, however, by the Anna Monika Foundation,
just passed through your city on route St. Moritz. The award, for
efforts in developing a theory of convulsive therapy and my 25 years
of research, was a special honor, as I believe
award to BCT since 1958.
me know
it
was
the
first
such
I await your reprints and will probably read them. Let
whether I should send them on, and to whom.
My
best regards.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Max
�
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence to: Angst, Jules
Type
The nature or genre of the resource
Text
Identifier
An unambiguous reference to the resource within a given context
mfp-05-00-029-7-238
Date
A point or period of time associated with an event in the lifecycle of the resource
1979
Creator
An entity primarily responsible for making the resource
<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
Subject
The topic of the resource
Correspondence -- Correspondence
Relation
A related resource
The Max Fink Collection
Description
An account of the resource
Rights
Information about rights held in and over the resource
<a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a>
Source
A related resource from which the described resource is derived
Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
Language
A language of the resource
en-US
Format
The file format, physical medium, or dimensions of the resource
application/pdf
Publisher
An entity responsible for making the resource available
Contributor
An entity responsible for making contributions to the resource
Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/bb581e78418b8a2e194295b8d87af140.pdf
071d7ee07a508e4afdfa5b9427a77afa
PDF Text
Text
September 18, 1979
Mrs. K. Hildreth
Dept.
OB/GYN
630 West 168 Street
York City
New
Dear Mrs.
Hildreth,
u have received the invitation to continue participation
in the Neuroendocrine Journal Club, and have been asked to monitor two
journals, Brain
and Experimental Neurology.
I regret to say that I shall be moving my home to the
University, and it will be unlikely that I will be able to continue to
attend the meetings of the Club, or to participate further.
Please thank Drs. Ferin and Krieger for thinking of
Sincerely yours,
Max Fink, M.D.
Professor of Psychiatry
me.
�
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence to: Hildreth, K.
Type
The nature or genre of the resource
Text
Identifier
An unambiguous reference to the resource within a given context
mfp-05-00-029-7-235
Date
A point or period of time associated with an event in the lifecycle of the resource
1979
Creator
An entity primarily responsible for making the resource
<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
Subject
The topic of the resource
Correspondence -- Correspondence
Relation
A related resource
The Max Fink Collection
Description
An account of the resource
Rights
Information about rights held in and over the resource
<a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a>
Source
A related resource from which the described resource is derived
Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
Language
A language of the resource
en-US
Format
The file format, physical medium, or dimensions of the resource
application/pdf
Publisher
An entity responsible for making the resource available
Contributor
An entity responsible for making contributions to the resource
Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/60f88d30be23b1a800cb8debc78d4ebf.pdf
dcafe7e35431e3db547a9f9a3382505a
PDF Text
Text
9,495“
...
,.
-_.
.7.
-m-Wmu-r
.
mum."
3,“...
September 26, 1977
Dr. H. van Duijn
Valeriuskiiniek
Valeriusplein
9
Amsterdam, The Netherlands
a
-
Dear Dr. van DuiJn,
.W"...a~uw.,
,"flw
_.__
the
EEG
for the careful editing of my contribution to
issue.
I accept each of your suggestions and make
special
Than you
the following amendments.
pg 6,
par.
3: Replace sentence 1 with:
In the past ten years, approximately 70
have been studied by
~
<
:."'-'m'
*n’4.~“'lI-'me.w‘llsar
quantitative
EEG
new chemical
methods (Table
III).
entities
pg,8 and others: I have checked the dosage schedule as reported by
Itil in a number of reports and the proper dosages are
20 to 300 milligrams orally given; and 500, 600, 1000 and 1200
micrograms. Please correct the text using the proper symbols for the
measures.
-
Also, page 8,
v-'
uW'
With TRH,
.—
report
.
.
.
Itil
line
6 should be
(197ha) and
corrected to read:
Itil
and
his
co—vorkers (197ha, 1975)
va'wl-JW‘DV'
‘
:-
Table 2: The coreection can be made by adding to the top of the table,
the following phrase, centered under the heading:
"aver—um.“
(As
Vaw‘wrvwn
defined in Table I)
l. Abuzzahab. The correct citation is
Clinical Research $39-15, 1970.
Reference #
American Journal of
mr
v.-
date on the volume by Matecjek and Schenk is 1975.
page 12:
The only
page 16:
Blackman and Tukey (1958)
is correct.
Citations: Deletedthe citation
errors.
citation list.
by Irwin and Fink (1975) from the
The sentence above, page 8, corrects the other
I trust these corrections are helpful.
Many
thanks.
Sincerely yours,
,
,
rvmwm
Max
Fink,
M.D.
�
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence to: van Duijn, Haus
Type
The nature or genre of the resource
Text
Identifier
An unambiguous reference to the resource within a given context
mfp-05-00-029-7-233
Date
A point or period of time associated with an event in the lifecycle of the resource
1979
Creator
An entity primarily responsible for making the resource
<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
Subject
The topic of the resource
Correspondence -- Correspondence
Relation
A related resource
The Max Fink Collection
Description
An account of the resource
Rights
Information about rights held in and over the resource
<a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a>
Source
A related resource from which the described resource is derived
Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
Language
A language of the resource
en-US
Format
The file format, physical medium, or dimensions of the resource
application/pdf
Publisher
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Contributor
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Correspondence
-
http://exhibits.library.stonybrook.edu/mfp/files/original/21f5c0e67c66a46ed86997977ac1838c.pdf
03aa7093af368094d7e96a245b179bd2
PDF Text
Text
mwmfl
April
A,
1979
Laura Bossi M.D. and
V.
Bettellochi,
L.E.R.S.
75013
Deer
Ph.D.
Paris, France
Drs.,
studies of new drugs and their classification
spread throughout the scientific literature. Many
reports bear the names of M. Fink, T. Itil, B. Seletu, J. Roubicek,
and M. Metecjek, among others. Some of the papers are cited in the
paper which I enclose. This represents the latest end most complete
summery 5f the methodology and its applications. For an earlier
set of papers, I suggeet you obtain a copy of "Psychotropic Drugs
and the Human EEG", edited by T. 1:11, 3. Kerger, 1974.
by
The
EEG
criteria are
If you are planning to undertake the assessment of
using quantitative EEG (camputerised EEG), I suggest that
.you visit one of the laboratories that ere using the method. The
techniques are distinctly different than conventional EEG, sleep EEG,
and averaged evoked potentials, and it is en edventage to see a
»
new compounds
system in operation.
Good
luck.
Sincerely yours,
Fink, M.D.
Professor of Psychiatry
Mex
�
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Correspondence to: Bossi, Laura
Type
The nature or genre of the resource
Text
Identifier
An unambiguous reference to the resource within a given context
mfp-05-00-029-6-230
Date
A point or period of time associated with an event in the lifecycle of the resource
1979
Creator
An entity primarily responsible for making the resource
<a title="Fink, Max, 1923-" href="http://id.loc.gov/authorities/names/n79039548" target="_blank">Fink, Max, 1923-</a>
Subject
The topic of the resource
Correspondence -- Correspondence
Relation
A related resource
The Max Fink Collection
Description
An account of the resource
Rights
Information about rights held in and over the resource
<a title="IN COPYRIGHT - EDUCATIONAL USE PERMITTED" href="http://rightsstatements.org/vocab/InC-EDU/1.0/" target="_blank">IN COPYRIGHT - EDUCATIONAL USE PERMITTED</a>
Source
A related resource from which the described resource is derived
Special Collections and University Archives, University Libraries. Stony Brook University Libraries (State University of New York).
Language
A language of the resource
en-US
Format
The file format, physical medium, or dimensions of the resource
application/pdf
Publisher
An entity responsible for making the resource available
Contributor
An entity responsible for making contributions to the resource
Correspondence